Michael Cowley

Q: What Schools Are Affiliated With Michael Cowley

Michael Cowley is affiliated with the following schools: University of Melbourne, Oregon Health & Science University, Monash University

Michael Cowley's AcademicInfluence.com Rankings

Michael Cowley

Biology

#5598

World Rank

#8114

Historical Rank

Physiology

#262

World Rank

#463

Historical Rank

biology Degrees

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Biology

Michael Cowley's Degrees

PhD Exercise Physiology University of Melbourne

Why Is Michael Cowley Influential?

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According to Wikipedia, Michael Cowley FTSE is an Australian physiologist. He is best known for his mapping of the neural circuits involved in metabolism and obesity and diabetes treatment. He is a professor in the Department of Physiology at Monash University in the Faculty of Biomedical and Psychological Sciences. He is also a director of the Australian diabetes drug development company, Verva Inc, and director of the Monash Obesity & Diabetes Institute] .

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Michael Cowley's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Gut hormone PYY3-36 physiologically inhibits food intake (2002) (2237)
Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus (2001) (2199)
The Distribution and Mechanism of Action of Ghrelin in the CNS Demonstrates a Novel Hypothalamic Circuit Regulating Energy Homeostasis (2003) (1599)
Mechanisms of leptin action and leptin resistance. (2008) (983)
Leptin Directly Activates SF1 Neurons in the VMH, and This Action by Leptin Is Required for Normal Body-Weight Homeostasis (2006) (716)
Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity (2007) (665)
Insulin action in AgRP-expressing neurons is required for suppression of hepatic glucose production. (2007) (638)
Integration of NPY, AGRP, and Melanocortin Signals in the Hypothalamic Paraventricular Nucleus Evidence of a Cellular Basis for the Adipostat (1999) (598)
The arcuate nucleus as a conduit for diverse signals relevant to energy homeostasis (2001) (578)
The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss. (2014) (545)
Diet-induced obesity causes severe but reversible leptin resistance in arcuate melanocortin neurons. (2007) (538)
Activation of Central Melanocortin Pathways by Fenfluramine (2002) (466)
Synaptic input organization of the melanocortin system predicts diet-induced hypothalamic reactive gliosis and obesity (2010) (380)
Serotonin Reciprocally Regulates Melanocortin Neurons to Modulate Food Intake (2006) (375)
Ghrelin (2015) (371)
Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice. (2008) (340)
Leptin Resistance and Obesity (2006) (308)
Hypothalamic POMC neurons promote cannabinoid-induced feeding (2015) (307)
Leptin and Insulin Act on POMC Neurons to Promote the Browning of White Fat (2015) (305)
Leptin Mediates the Increase in Blood Pressure Associated with Obesity (2014) (283)
Disruption of neurotransmission in Drosophila mushroom body blocks retrieval but not acquisition of memory (273)
Rational Design of a Combination Medication for the Treatment of Obesity (2009) (270)
Diet-induced obesity causes ghrelin resistance in arcuate NPY/AgRP neurons. (2010) (258)
Leptin Action in the Dorsomedial Hypothalamus Increases Sympathetic Tone to Brown Adipose Tissue in Spite of Systemic Leptin Resistance (2011) (255)
Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance. (2011) (170)
Chronic Treatment With a Melanocortin-4 Receptor Agonist Causes Weight Loss, Reduces Insulin Resistance, and Improves Cardiovascular Function in Diet-Induced Obese Rhesus Macaques (2013) (165)
Central Serotonin and Melanocortin Pathways Regulating Energy Homeostasis (2003) (162)
Comparison of combined bupropion and naltrexone therapy for obesity with monotherapy and placebo. (2009) (158)
Peptide YY is a regulator of energy homeostasis in obese children before and after weight loss. (2005) (152)
Early overnutrition results in early-onset arcuate leptin resistance and increased sensitivity to high-fat diet. (2010) (147)
The electrophysiology of feeding circuits (2004) (146)
Regulation of central melanocortin signaling by interleukin-1 beta. (2007) (134)
Hypothalamic Circuitry of Neuropeptide Y Regulation of Neuroendocrine Function and Food Intake via the Y5 Receptor Subtype (2001) (131)
Electrophysiological Actions of Peripheral Hormones on Melanocortin Neurons (2003) (122)
Naltrexone/bupropion for obesity: an investigational combination pharmacotherapy for weight loss. (2014) (119)
Starvation after AgRP neuron ablation is independent of melanocortin signaling (2008) (116)
Physiological Evidence for the Involvement of Peptide YY in the Regulation of Energy Homeostasis in Humans (2006) (115)
Coenzyme Q induces nigral mitochondrial uncoupling and prevents dopamine cell loss in a primate model of Parkinson's disease. (2003) (114)
The Role of Thermogenesis in Antipsychotic Drug‐induced Weight Gain (2009) (107)
Peptide YY(3-36) inhibits morning, but not evening, food intake and decreases body weight in rhesus macaques. (2005) (99)
Excess weight gain during the early postnatal period is associated with permanent reprogramming of brown adipose tissue adaptive thermogenesis. (2007) (96)
Estradiol prevents fat accumulation and overcomes leptin resistance in female high-fat diet mice. (2014) (88)
Hypothalamic melanocortin neurons integrate signals of energy state. (2003) (85)
New insights in leptin resistance mechanisms in mice (2015) (83)
Regulation of agouti-related protein messenger ribonucleic acid transcription and peptide secretion by acute and chronic inflammation. (2008) (82)
Appropriate Inhibition of Orexigenic Hypothalamic Arcuate Nucleus Neurons Independently of Leptin Receptor/STAT3 Signaling (2007) (78)
Developmental Switch in Neuropeptide Y and Melanocortin Effects in the Paraventricular Nucleus of the Hypothalamus (2007) (73)
Leptin Stimulates Neuropeptide Y and Cocaine Amphetamine-Regulated Transcript Coexpressing Neuronal Activity in the Dorsomedial Hypothalamus in Diet-Induced Obese Mice (2013) (69)
Insulin regulates POMC neuronal plasticity to control glucose metabolism (2018) (67)
The melanocortin pathway and energy homeostasis: From discovery to obesity therapy (2021) (64)
Developmental Switch of Leptin Signaling in Arcuate Nucleus Neurons (2014) (64)
Hypothalamic Insulin Resistance in Obesity: Effects on Glucose Homeostasis (2017) (63)
Ghrelin--satisfying a hunger for the mechanism. (2004) (60)
Is ghrelin a signal for the development of metabolic systems? (2005) (56)
Characterization of brainstem peptide YY (PYY) neurons (2008) (55)
Hypertension in obesity: is leptin the culprit? (2013) (52)
Physiology: Does gut hormone PYY3–36 decrease food intake in rodents? (reply) (2004) (52)
Neuropeptide Y Y5 receptor protein in the cortical/limbic system and brainstem of the rat: expression on γ-aminobutyric acid and corticotropin-releasing hormone neurons (2000) (50)
Inhibition of Dopamine and Norepinephrine Reuptake Produces Additive Effects on Energy Balance in Lean and Obese Mice (2007) (50)
Abdominal fat analyzed by DEXA scan reflects visceral body fat and improves the phenotype description and the assessment of metabolic risk in mice. (2012) (49)
Feeding Induced by Cannabinoids Is Mediated Independently of the Melanocortin System (2008) (48)
Catecholamine Reuptake Inhibition Causes Weight Loss by Increasing Locomotor Activity and Thermogenesis (2008) (46)
Pancreatic polypeptide in obese children before and after weight loss (2006) (45)
Suppression of basal spontaneous gonadotropin-releasing hormone neuronal activity during lactation: role of inhibitory effects of neuropeptide Y. (2009) (44)
Leptin reduces food intake via a dopamine D2 receptor-dependent mechanism. (2012) (44)
Changes of peripheral alpha-melanocyte-stimulating hormone in childhood obesity. (2010) (44)
Treatment of type 2 diabetes with the designer cytokine IC7Fc (2019) (42)
Zonisamide Prevents Olanzapine-Associated Hyperphagia, Weight Gain, and Elevated Blood Glucose in Rats (2008) (42)
Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus. (2018) (40)
Intranasal Targeting of Hypothalamic PTP1B and TCPTP Reinstates Leptin and Insulin Sensitivity and Promotes Weight Loss in Obesity. (2019) (40)
Serotonergic pathways converge upon central melanocortin systems to regulate energy balance (2005) (40)
Celastrol-Induced Weight Loss Is Driven by Hypophagia and Independent From UCP1 (2018) (37)
Deletion of hepatic carbohydrate response element binding protein (ChREBP) impairs glucose homeostasis and hepatic insulin sensitivity in mice (2017) (36)
A Hypothalamic Phosphatase Switch Coordinates Energy Expenditure with Feeding. (2017) (36)
Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes (2018) (35)
α-Melanocyte stimulating hormone promotes muscle glucose uptake via melanocortin 5 receptors (2016) (33)
Evidence for differential regulation of multiple transcripts of the gonadotropin releasing hormone receptor in the ovine pituitary gland; effect of estrogen (1998) (33)
Effects of Bariatric Surgery on Liver Function Tests in Patients with Nonalcoholic Fatty Liver Disease (2017) (33)
A BAT-Centric Approach to the Treatment of Diabetes: Turn on the Brain. (2016) (32)
Leptin increasing sympathetic nerve outflow in obesity (2012) (32)
To be or NUCB2, is nesfatin the answer? (2006) (31)
Sex differences in the metabolic effects of testosterone in sheep. (2012) (30)
Short‐term high‐fat diet increases the presence of astrocytes in the hypothalamus of C57BL6 mice without altering leptin sensitivity (2017) (30)
Modified thresholds for fibrosis risk scores in nonalcoholic fatty liver disease are necessary in the obese (2016) (29)
Leptin Signaling in the Arcuate Nucleus Reduces Insulin's Capacity to Suppress Hepatic Glucose Production in Obese Mice. (2019) (27)
Paradoxical Effect of Gonadotrophin‐Inhibiting Hormone to Negatively Regulate Neuropeptide Y Neurones in Mouse Arcuate Nucleus (2013) (26)
Brain Feeding Circuits after Roux-en-Y Gastric Bypass (2018) (22)
Hyperphagia in male melanocortin 4 receptor deficient mice promotes growth independently of growth hormone (2016) (19)
Excess of nerve growth factor in the ovary causes a polycystic ovary-like syndrome in mice, which closely resembles both reproductive and metabolic aspects of the human syndrome. (2014) (19)
A Pre-Hospital Patient Education Program Improves Outcomes of Bariatric Surgery (2016) (19)
Does leptin cause an increase in blood pressure in animals and humans? (2017) (18)
Estrogen Transiently Increases Delayed Rectifier, Voltage-Dependent Potassium Currents in Ovine Gonadotropes (1999) (17)
Repeated weight cycling in obese mice causes increased appetite and glucose intolerance (2018) (15)
Plasticity of calcium-permeable AMPA glutamate receptors in Pro-opiomelanocortin neurons (2017) (14)
Persistent Leptin Signaling in the Arcuate Nucleus Impairs Hypothalamic Insulin Signaling and Glucose Homeostasis in Obese Mice (2019) (13)
Prevention of the adverse effects of olanzapine on lipid metabolism with the antiepileptic zonisamide (2017) (13)
GLP-1 analogs: satiety without malaise? (2007) (13)
Dapagliflozin restores insulin and growth hormone secretion in obese mice. (2020) (12)
Mitochondrial uncoupling in the melanocortin system differentially regulates NPY and POMC neurons to promote weight-loss (2017) (12)
Weight loss after laparoscopic adjustable gastric band and resolution of the metabolic syndrome and its components (2017) (12)
Changes in the binding characteristics of the μ, δ and κ subtypes of the opioid receptor in the hypothalamus of the normal cyclic ewe and in the ovariectomised ewe following treatment with ovarian steroids (1996) (11)
To be or NUCB 2 , is nesfatin the answer ? (10)
Dietary Macronutrient Composition Directs ChREBP Isoform Expression and Glucose Metabolism in Mice (2016) (10)
Hypothalamic regulatory pathways and potential obesity treatment targets (2006) (9)
Deficient melanocortin-4 receptor causes abnormal reproductive neuroendocrine profile in female mice. (2017) (9)
α-MSH Stimulates Glucose Uptake in Mouse Muscle and Phosphorylates Rab-GTPase-Activating Protein TBC1D1 Independently of AMPK (2016) (8)
Erratum: A Hypothalamic Phosphatase Switch Coordinates Energy Expenditure with Feeding (Cell Metabolism (2017) 26(2) (375–393.e7) (S1550413117304345) (10.1016/j.cmet.2017.07.013)) (2017) (8)
Current and emerging pharmacotherapies for obesity in Australia. (2017) (8)
A Double-Blind, Placebo-, Bupropion- and Naltrexone-Controlled Study of the Efficacy and Safety of Three Doses of Naltrexone-Bupropion SR Combination Therapy in Obesity: Effects on Total and Visceral Adipose Tissue and CV Risk Markers (2006) (7)
The role of pharmacotherapy in the prevention and treatment of paediatric metabolic syndrome--Implications for long-term health: part of a series on Pediatric Pharmacology, guest edited by Gianvincenzo Zuccotti, Emilio Clementi, and Massimo Molteni. (2012) (7)
Transmitter time: synaptic plasticity and metabolic memory in the hypothalamus. (2012) (7)
A Hypothalamic Phosphatase Switch Coordinates Energy Expenditure with Feeding. (2017) (7)
Stimulation of endogenous pulsatile growth hormone secretion by activation of growth hormone secretagogue receptor reduces the fat accumulation and improves the insulin sensitivity in obese mice (2020) (6)
Determining the Effects of Combined Liraglutide and Phentermine on Metabolic Parameters, Blood Pressure, and Heart Rate in Lean and Obese Male Mice (2019) (6)
Obesity: The Problem and Its Management (2010) (6)
Reelin is modulated by diet-induced obesity and has direct actions on arcuate proopiomelanocortin neurons (2019) (5)
Effects of nutritional manipulation on body composition in the developing marsupial, Macropus eugenii (2016) (5)
Changes in the binding characteristics of the mu, delta and kappa subtypes of the opioid receptor in the hypothalamus of the normal cyclic ewe and in the ovariectomised ewe following treatment with ovarian steroids. (1996) (4)
Speed-dieting: dopamine agonists promote weight loss (2019) (3)
Leptin Effects on DAT Neurons To Control Energy Homeostasis. (2017) (2)
Time-Restricted Feeding Restored Insulin-Growth Hormone Balance and Improved Substrate and Energy Metabolism in MC4RKO Obese Mice (2021) (2)
Elevated Hypothalamic TCPTP in Obesity Contributes to Cellular Leptin Resistance. (2012) (2)
WITHDRAWN: The VTA modulates feeding behavior induced by cannabinoid receptor antagonists in both wild-type and Agouti mice (2006) (1)
Universitet-MSH stimulates glucose uptake in mouse muscle and phosphorylates Rab-GTPase-activating protein TBC 1 D 1 independently of AMPK (2016) (1)
Suppression of Basal Spontaneous GnRH Neuronal Activity during Lactation: Role of Inhibitory Effects of NPY (2008) (1)
SUN-672 SGLT2 Inhibitor Reduces Hyperinsulinemia and Restores Pulsatile Growth Hormone Secretion in Obese MC4RKO Mice (2020) (1)
CHAPTER 26 – Practical Approaches to Pharmacological Studies in Nonhuman Primates (2005) (1)
Ghrelin: Neuropeptide Regulator of Metabolism (2012) (1)
Endocrinology of Fat, Metabolism, and Appetite (2005) (1)
The role of leptin signalling in the development of cardiovascular diseases in obesity (2017) (1)
Publisher Correction: Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes (2018) (1)
Erratum. Celastrol-Induced Weight Loss Is Driven by Hypophagia and Independent From UCP1. Diabetes 2018;67:2456–2465 (2019) (1)
Title: Regulation of AgRP mRNA transcription and peptide secretion by acute and chronic inflammation (2008) (1)
Using intranasal lidocaine to reduce food intake (2007) (1)
Antipsychotic drug induced metabolic dysfunction and its amelioration using zonisamide (2011) (0)
Publisher Correction: Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes (2018) (0)
Crosstalk between hypothalamic leptin and insulin signalling in obesity (2019) (0)
Intranasal Targeting of Hy pothalamic PTP 1 B and TCPTP Reinstates Leptin and Insulin Sensitivity and Promotes Weight Loss in Obesity Graphical Abstract Highlights (2019) (0)
Leptin is a key regulator of glucose homeostasis in obesity (2019) (0)
The role of leptin in leptin resistance and obesity (2006) (0)
225 IF LEPTIN IS THE CULPRIT, IS ESTROGEN THE ANTAGONIST IN OBESITY ASSOCIATED HYPERTENSION? (2012) (0)
Non-humanoid primate model of diet-induced obesity: model validation for biomarker discovery (2019) (0)
How does PYY 3-36 improve glucose tolerance? (2016) (0)
Constitutive knockout of Gpr21 inhibits the ex vivo migration of mouse immune cells (2017) (0)
The Gut Hormone Peptide YY3-36 (PYY3-36) Regulates Appetite in Normal and Overweight Volunteers (2003) (0)
Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes (2018) (0)
Melanocortin circuits in obese mice do not respond to leptin (2006) (0)
Compositions that affect weight loss. (2004) (0)
WITHDRAWN: Dopamine and norepinephrine reuptake inhibition both contribute to bupropion-induced hypophagia in obese mice (2006) (0)
ORIGINAL ARTICLE Using intranasal lidocaine to reduce food intake (2007) (0)
Food hypersensitivity-induced chronic gastrointestinal inflammation in a non-human primate model of diet-induced obesity (2019) (0)
Persistent leptin signalling in the arcuate nucleus reduces insulin's capacity to suppress hepatic glucose production in obese mice (2019) (0)
assessment of metabolic risk in mice body fat and improves the phenotype description and the Abdominal fat analyzed by DEXA scan reflects visceral (2012) (0)
PEDIATRIC HIGHLIGHT Pancreatic polypeptide in obese children before and after weight loss (2006) (0)
GP1-6: Metabolic requirements to sustain NEFA and glucose homeostasis overrides the role of growth hormone in promoting rapid linear growth in hyperphagic MC4RKO mice (2014) (0)
Peripheral alpha MSH in childhood obesity and craniopharyngioma (2008) (0)
Pyy3-36 pour pour la reduction ou la prevention de l'obesite (2002) (0)
Novel insights into central regulation of food intake (2016) (0)
Changes of peripheral [alpha]-melanocortin stimulating hormone ([alpha]-MSH) in childhood craniopharyngioma patients in comparison with other forms of childhood obesity (2012) (0)
The role of thermogenesis in antipsychotic drug-induced obesity (2008) (0)
Correction: α-MSH Stimulates Glucose Uptake in Mouse Muscle and Phosphorylates Rab-GTPase-Activating Protein TBC1D1 Independently of AMPK (2016) (0)
Author response: Plasticity of calcium-permeable AMPA glutamate receptors in Pro-opiomelanocortin neurons (2017) (0)
Brain control of blood glucose (2019) (0)
Does activation of TRPM8 with menthol or icilin reduce blood glucose and body weight? (2019) (0)

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What Schools Are Affiliated With Michael Cowley?

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