Michael Elowitz

Q: What Schools Are Affiliated With Michael Elowitz

Michael Elowitz is affiliated with the following schools: University of California, Berkeley, McGill University, Weizmann Institute of Science, California Institute of Technology, Princeton University, Rockefeller University, Columbia University, University of Texas Southwestern Medical Center

Michael Elowitz's AcademicInfluence.com Rankings

Michael Elowitz

Biology

#1804

World Rank

#2926

Historical Rank

#862

USA Rank

Systems Biology

#11

World Rank

#11

Historical Rank

USA Rank

Molecular Biology

#459

World Rank

#468

Historical Rank

#147

USA Rank

biology Degrees

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Biology

Michael Elowitz's Degrees

PhD Physics Princeton University

Why Is Michael Elowitz Influential?

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According to Wikipedia, Michael B. Elowitz is a biologist and professor of Biology, Bioengineering, and Applied Physics at the California Institute of Technology, and investigator at the Howard Hughes Medical Institute. In 2007 he was the recipient of the Genius grant, better known as the MacArthur Fellows Program for the design of a synthetic gene regulatory network, the Repressilator, which helped initiate the field of synthetic biology. He was the first to show how inherently random effects, or 'noise', in gene expression could be detected and quantified in living cells, leading to a growing recognition of the many roles that noise plays in living cells. His work in Synthetic Biology and Noise represent two foundations of the field of Systems Biology. Since then, his laboratory has contributed to the development of synthetic biological circuits that perform a range of functions inside cells, and revealed biological circuit design principles underlying epigenetic memory, cell fate control, cell-cell communication, and multicellular behaviors.

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Michael Elowitz's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

A synthetic oscillatory network of transcriptional regulators (2000) (4352)
Stochastic Gene Expression in a Single Cell (2002) (3068)
Intrinsic and extrinsic contributions to stochasticity in gene expression (2002) (1599)
Functional roles for noise in genetic circuits (2010) (1406)
Gene Regulation at the Single-Cell Level (2005) (1119)
Dynamics of the p53-Mdm2 feedback loop in individual cells (2004) (1010)
An excitable gene regulatory circuit induces transient cellular differentiation (2006) (752)
Negative autoregulation speeds the response times of transcription networks. (2002) (705)
Protein Mobility in the Cytoplasm ofEscherichia coli (1999) (603)
Cis Interactions between Notch and Delta Generate Mutually Exclusive Signaling States (2010) (574)
Modeling a synthetic multicellular clock: repressilators coupled by quorum sensing. (2004) (563)
Combinatorial Synthesis of Genetic Networks (2002) (544)
Frequency-modulated nuclear localization bursts coordinate gene regulation (2008) (482)
Tunability and Noise Dependence in Differentiation Dynamics (2007) (462)
Reconstruction of genetic circuits (2005) (365)
Programming gene expression with combinatorial promoters (2007) (362)
Functional Roles of Pulsing in Genetic Circuits (2013) (348)
Dynamics of epigenetic regulation at the single-cell level (2016) (335)
Measuring single-cell gene expression dynamics in bacteria using fluorescence time-lapse microscopy (2011) (334)
Synthetic recording and in situ readout of lineage information in single cells (2016) (329)
Synthetic Biology: Integrated Gene Circuits (2011) (292)
Architecture-Dependent Noise Discriminates Functionally Analogous Differentiation Circuits (2009) (269)
Dynamic Heterogeneity and DNA Methylation in Embryonic Stem Cells (2014) (268)
Regulatory activity revealed by dynamic correlations in gene expression noise (2008) (249)
Using movies to analyse gene circuit dynamics in single cells (2009) (239)
Positive Feedback Between PU.1 and the Cell Cycle Controls Myeloid Differentiation (2013) (232)
Challenges and emerging directions in single-cell analysis (2017) (223)
Dynamic Ligand Discrimination in the Notch Signaling Pathway (2018) (211)
Realizing the potential of synthetic biology (2014) (208)
Build life to understand it (2010) (200)
Stochastic Pulse Regulation in Bacterial Stress Response (2011) (195)
The ePetri dish, an on-chip cell imaging platform based on subpixel perspective sweeping microscopy (SPSM) (2011) (194)
Programmable protein circuits in living cells (2018) (188)
The presence of p53 mutations in human osteosarcomas correlates with high levels of genomic instability (2003) (187)
Combinatorial Signal Perception in the BMP Pathway (2017) (166)
Photoactivation turns green fluorescent protein red (1997) (156)
Single-cell transcriptome analysis reveals dynamic changes in lncRNA expression during reprogramming. (2015) (144)
Mutual Inactivation of Notch Receptors and Ligands Facilitates Developmental Patterning (2011) (135)
Partial penetrance facilitates developmental evolution in bacteria (2009) (131)
Rate of environmental change determines stress response specificity (2013) (130)
Chromophore-assisted light inactivation and self-organization of microtubules and motors. (1998) (127)
Combinatorial gene regulation by modulation of relative pulse timing (2015) (120)
Fringe proteins modulate Notch-ligand cis and trans interactions to specify signaling states (2014) (120)
Asynchronous combinatorial action of four regulatory factors activates Bcl11b for T cell commitment (2016) (110)
Pulsed Feedback Defers Cellular Differentiation (2012) (104)
A General Mechanism for Network-Dosage Compensation in Gene Circuits (2010) (95)
A fluctuation method to quantify in vivo fluorescence data. (2006) (89)
Morphogen gradient reconstitution reveals Hedgehog pathway design principles (2018) (82)
Accurate prediction of gene feedback circuit behavior from component properties (2007) (80)
A synthetic three-color scaffold for monitoring genetic regulation and noise (2010) (74)
Inferring Cell-State Transition Dynamics from Lineage Trees and Endpoint Single-Cell Measurements. (2016) (71)
The evolutionary dynamics of the Saccharomyces cerevisiae protein interaction network after duplication (2008) (69)
What Is Your Conceptual Definition of "Cell Type" in the Context of a Mature Organism? (2017) (66)
Pulsatile Dynamics in the Yeast Proteome (2014) (64)
Metabolic interactions between dynamic bacterial subpopulations (2017) (60)
Imaging cell lineage with a synthetic digital recording system (2020) (57)
Cis-activation in the Notch signaling pathway (2018) (54)
An STM study of molecular-beam epitaxy growth of GaAs (1993) (52)
Communication codes in developmental signaling pathways (2019) (51)
A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment (2018) (51)
Tracking Cell Signals in Fluorescent Images (2005) (46)
An operational view of intercellular signaling pathways (2017) (45)
In situ readout of DNA barcodes and single base edits facilitated by in vitro transcription (2019) (39)
Constitutive splicing and economies of scale in gene expression (2019) (34)
Synthetic multistability in mammalian cells (2021) (34)
Embryo model completes gastrulation to neurulation and organogenesis (2022) (33)
Nutritional supplement chromium picolinate causes sterility and lethal mutations in Drosophila melanogaster (2003) (32)
Brf1 posttranscriptionally regulates pluripotency and differentiation responses downstream of Erk MAP kinase (2014) (27)
Programmable protein circuit design (2021) (27)
Molecular Time Sharing through Dynamic Pulsing in Single Cells (2018) (26)
Ligand-receptor promiscuity enables cellular addressing (2020) (26)
Synthetic mammalian signaling circuits for robust cell population control (2020) (22)
Benchmarked approaches for reconstruction of in vitro cell lineages and in silico models of C. elegans and M. musculus developmental trees. (2021) (20)
Dynamical Consequences of Bandpass Feedback Loops in a Bacterial Phosphorelay (2011) (19)
A simple direct RT-LAMP SARS-CoV-2 saliva diagnostic (2020) (19)
Synthetic biology of multicellular systems: new platforms and applications for animal cells and organisms. (2014) (16)
The context-dependent, combinatorial logic of BMP signaling (2020) (14)
Polyphasic feedback enables tunable cellular timers (2014) (13)
Transport, assembly, and dynamics in systems of interacting proteins (1999) (11)
Self-Amplifying Pulsatile Protein Dynamics without Positive Feedback. (2018) (10)
Following evolution of bacterial antibiotic resistance in real time (2011) (9)
Erratum: The presence of p53 mutations in human osteosarcomas correlates with high levels of genomic instability (Proceedings of the National Academy of Sciences of the United States of America (September 30, 2003) 100:20 (11547-11552)) (2003) (8)
Synthetic biology: Precision timing in a cell (2016) (8)
Dynamics and functional roles of splicing factor autoregulation (2020) (7)
Protease-controlled secretion and display of intercellular signals (2021) (6)
Central Dogma Goes Digital. (2016) (6)
Systems biology: Deviations in mating (2005) (5)
Advancing towards a global mammalian gene regulation model through single-cell analysis and synthetic biology (2017) (5)
Supporting Online Material for Tunability and Noise Dependence in Differentiation Dynamics (2007) (4)
The sound of silence: Transgene silencing in mammalian cell engineering. (2022) (4)
Periodic spatial patterning with a single morphogen (2022) (3)
Challenges and emerging directions in single-cell analysis (2017) (3)
Correction: Fringe proteins modulate Notch-ligand cis and trans interactions to specify signaling states (2014) (3)
A synthetic protein-level neural network in mammalian cells (2022) (3)
Mixed messages: how bacteria resolve conflicting signals. (2011) (2)
Mutual inactivation of Notch and Delta permits a simple mechanism for lateral inhibition patterning (2010) (2)
Supporting Online Material for Stochastic Pulse Regulation in Bacterial Stress Response (2011) (2)
Engineering multiple levels of specificity in an RNA viral vector (2020) (1)
Molecular Cell Resource Dynamic Heterogeneity and DNA Methylation in Embryonic Stem Cells (2014) (1)
Combinatorial expression motifs in signaling pathways (2022) (1)
Single cell biology—a Keystone Symposia report (2021) (1)
Quantitative single-cell splicing analysis reveals an ‘economy of scale’ filter for gene expression (2018) (0)
Molecular Cell Technology Preview Central Dogma Goes Digital (2016) (0)
Benchmarked approaches for cell lineage reconstructions of in vitro dividing cells and in 1 silico models of Caenorhabditis elegans and Mus musculus developmental trees (2021) (0)
Author response: Cis-activation in the Notch signaling pathway (2018) (0)
Constitutive splicing and economies of scale in gene expression (2019) (0)
Abstract 1984: Cell fate reprogramming of liver tumor-initiating stem-like cells via phosphorylated NUMB and TBC1D15 (2018) (0)
Report Pulsatile Dynamics in the Yeast Proteome (2014) (0)
Regulation and Fluctuation of a Genetic Element at the Single-Cell Level (2004) (0)
Publisher Correction: In situ readout of DNA barcodes and single base edits facilitated by in vitro transcription (2020) (0)
Cis-activation in the Notch signaling pathway 1 (0)
Publisher Correction: In situ readout of DNA barcodes and single base edits facilitated by in vitro transcription (2020) (0)
COMET P/19 (1999) (0)
Molecular Cell Previews Mixed Messages : How Bacteria Resolve Conflicting Signals (2011) (0)
Regulation Revealed by Correlations in Gene Expression Noise (0)
Alternative splicing of GSDMB modulates killer lymphocyte–triggered pyroptosis (2023) (0)
Author response: Metabolic interactions between dynamic bacterial subpopulations (2018) (0)
The repressilator: a synthetic oscillatory network in E. coli (2002) (0)
Novel NOTCH-Binding Protein Directs Self-Renewal of Tumor-Initiating Stem-like Cells and HCC Development through Cell Fate Reprogramming (2018) (0)
Signaling Dynamics at the Single Cell Level (2010) (0)
HoxA3 Controls Notch Pathway to Repress Blood Development (2014) (0)
Chip-scale Microscopy for On-chip Cell Monitoring (2012) (0)
Structural Insights into the Assembly and Function of the SAGA Deubiquitinating Module (2010) (0)
Mutual inactivation of Notch and Delta amplifies differences between neighboring cells (2009) (0)
Principles of gene circuit design (2017) (0)
Ratiometric RNA labeling allows dynamic multiplexed analysis of gene circuits in single cells (2021) (0)
Supplementary Materials for Programmable protein circuits in living cells (2018) (0)
Cell signaling at the single-cell level (2013) (0)
Report in the Yeast Proteome (2014) (0)
Dissecting the transcriptional regulatory network for early T-cell commitment (2016) (0)
Protease-controlled secretion and display of intercellular signals (2022) (0)
In situ readout of DNA barcodes and single base edits facilitated by in vitro transcription (2019) (0)
NCBS SYMPOSIUM ON MOLECULES, MACHINES AND NETWORKS (2003) (0)
Macrophage and T-cell fate control: insights from tracking transcription factor dynamics in single cells (2014) (0)

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Other Resources About Michael Elowitz

en.wikipedia.org

What Schools Are Affiliated With Michael Elowitz?

Michael Elowitz is affiliated with the following schools:

Michael Elowitz's Academic­Influence.com Rankings

Michael Elowitz's Degrees

Why Is Michael Elowitz Influential?

Michael Elowitz's Published Works

Published Works

Other Resources About Michael Elowitz

What Schools Are Affiliated With Michael Elowitz?

Michael Elowitz's AcademicInfluence.com Rankings