Michael Fischbach
#62,171
Most Influential Person Now
American chemist, microbiologist, and geneticist
Michael Fischbach's AcademicInfluence.com Rankings
Michael Fischbachbiology Degrees
Biology
#4121
World Rank
#6192
Historical Rank
Microbiology
#605
World Rank
#673
Historical Rank
Genetics
#1162
World Rank
#1261
Historical Rank
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Chemistry Biology
Michael Fischbach's Degrees
- PhD Chemistry Stanford University
Why Is Michael Fischbach Influential?
(Suggest an Edit or Addition)According to Wikipedia, Michael Andrew Fischbach is an American chemist, microbiologist, and geneticist. He is an associate professor of Bioengineering and ChEM-H Faculty Fellow at Stanford University and a Chan Zuckerberg Biohub Investigator.
Michael Fischbach's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Diet rapidly and reproducibly alters the human gut microbiome (2013) (6748)
- A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations (2010) (2088)
- antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters (2015) (1653)
- Antibiotics for Emerging Pathogens (2009) (1596)
- antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences (2011) (1435)
- Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. (2013) (1360)
- Genome sequence and analysis of the Irish potato famine pathogen Phytophthora infestans (2009) (1305)
- Assembly-line enzymology for polyketide and nonribosomal Peptide antibiotics: logic, machinery, and mechanisms. (2006) (1208)
- antiSMASH 2.0—a versatile platform for genome mining of secondary metabolite producers (2013) (777)
- Insights into Secondary Metabolism from a Global Analysis of Prokaryotic Biosynthetic Gene Clusters (2014) (677)
- A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites (2017) (617)
- Minimum Information about a Biosynthetic Gene cluster. (2015) (600)
- New antibiotics from bacterial natural products (2006) (570)
- Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis. (2008) (519)
- A Systematic Analysis of Biosynthetic Gene Clusters in the Human Microbiome Reveals a Common Family of Antibiotics (2014) (518)
- Small molecules from the human microbiota (2015) (508)
- Bile acid metabolites control Th17 and Treg cell differentiation (2018) (455)
- Natural products version 2.0: connecting genes to molecules. (2010) (400)
- Eating for two: how metabolism establishes interspecies interactions in the gut. (2011) (387)
- A Wave of Regulatory T Cells into Neonatal Skin Mediates Tolerance to Commensal Microbes. (2015) (384)
- Synthetic biology to access and expand nature's chemical diversity (2016) (369)
- Discovery and characterization of gut microbiota decarboxylases that can produce the neurotransmitter tryptamine. (2014) (362)
- Skin microbiota–host interactions (2018) (352)
- Cell-Based Therapeutics: The Next Pillar of Medicine (2013) (351)
- Computational approaches to natural product discovery. (2015) (341)
- Structurally diverse natural products that cause potassium leakage trigger multicellularity in Bacillus subtilis (2009) (340)
- A mass spectrometry-guided genome mining approach for natural product peptidogenomics (2011) (323)
- Dynamic control of liquid-core/liquid-cladding optical waveguides (2004) (297)
- How pathogenic bacteria evade mammalian sabotage in the battle for iron (2006) (297)
- A metabolomic view of how the human gut microbiota impacts the host metabolome using humanized and gnotobiotic mice (2013) (279)
- The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2 (2006) (279)
- The natural history of antibiotics (2009) (271)
- A Cardiovascular Disease-Linked Gut Microbial Metabolite Acts via Adrenergic Receptors (2020) (263)
- MAIT cells are imprinted by the microbiota in early life and promote tissue repair (2019) (262)
- A biosynthetic pathway for a prominent class of microbiota-derived bile acids (2015) (253)
- The evolution of gene collectives: How natural selection drives chemical innovation (2008) (249)
- Dysbiosis-Induced Secondary Bile Acid Deficiency Promotes Intestinal Inflammation. (2020) (244)
- The identification of bacillaene, the product of the PksX megacomplex in Bacillus subtilis (2007) (233)
- Microbiota-Targeted Therapies: An Ecological Perspective (2012) (224)
- Production of α-Galactosylceramide by a Prominent Member of the Human Gut Microbiota (2013) (197)
- Gut Microbiota-Produced Tryptamine Activates an Epithelial G-Protein-Coupled Receptor to Increase Colonic Secretion. (2018) (193)
- Mapping the Genetic Landscape of Human Cells (2018) (186)
- Combination therapies for combating antimicrobial resistance. (2011) (182)
- Thirteen posttranslational modifications convert a 14-residue peptide into the antibiotic thiocillin (2009) (175)
- One pathway, many products. (2007) (167)
- In vitro characterization of salmochelin and enterobactin trilactone hydrolases IroD, IroE, and Fes. (2005) (165)
- A singular enzymatic megacomplex from Bacillus subtilis (2007) (163)
- Discovery of Reactive Microbiota-Derived Metabolites that Inhibit Host Proteases (2017) (162)
- Modulation of a Circulating Uremic Solute via Rational Genetic Manipulation of the Gut Microbiota. (2016) (162)
- A metabolic pathway for bile acid dehydroxylation by the gut microbiome (2019) (162)
- Microbiome: Focus on Causation and Mechanism (2018) (160)
- A Systematic Computational Analysis of Biosynthetic Gene Cluster Evolution: Lessons for Engineering Biosynthesis (2014) (148)
- In vitro characterization of IroB, a pathogen-associated C-glycosyltransferase. (2005) (148)
- Mixing with bubbles: a practical technology for use with portable microfluidic devices. (2006) (138)
- What Lives On Our Skin: Ecology, Genomics and Therapeutic Opportunities Of the Skin Microbiome. (2013) (133)
- Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians (2021) (129)
- Total biosynthesis: in vitro reconstitution of polyketide and nonribosomal peptide pathways. (2008) (127)
- Metagenomic compendium of 189,680 DNA viruses from the human gut microbiome (2021) (125)
- Directed evolution can rapidly improve the activity of chimeric assembly-line enzymes (2007) (120)
- “Oncogenic Shock”: Explaining Oncogene Addiction through Differential Signal Attenuation (2006) (114)
- A metabolomics pipeline for the mechanistic interrogation of the gut microbiome (2021) (114)
- A biosynthetic gene cluster for the acetyl-CoA carboxylase inhibitor andrimid. (2006) (111)
- Recovery of the Gut Microbiota after Antibiotics Depends on Host Diet, Community Context, and Environmental Reservoirs. (2019) (111)
- Contextual control of skin immunity and inflammation by Corynebacterium (2018) (110)
- Signaling in Host-Associated Microbial Communities (2016) (109)
- Synthetic Microbes As Drug Delivery Systems (2014) (105)
- A Pressure Test to Make 10 Molecules in 90 Days: External Evaluation of Methods to Engineer Biology. (2018) (99)
- Community Health Care: Therapeutic Opportunities in the Human Microbiome (2011) (96)
- Experimental realization of a quantum quincunx by use of linear optical elements (2005) (94)
- IMG-ABC: A Knowledge Base To Fuel Discovery of Biosynthetic Gene Clusters and Novel Secondary Metabolites (2015) (93)
- Microbial Transplantation With Human Gut Commensals Containing CutC Is Sufficient to Transmit Enhanced Platelet Reactivity and Thrombosis Potential (2018) (92)
- The Prevalence of Species and Strains in the Human Microbiome: A Resource for Experimental Efforts (2014) (87)
- Design for mixing using bubbles in branched microfluidic channels (2005) (85)
- Role of dietary fiber in the recovery of the human gut microbiome and its metabolome. (2021) (80)
- A gut-derived metabolite alters brain activity and anxiety behaviour in mice (2022) (79)
- Bifidobacterium alters the gut microbiota and modulates the functional metabolism of T regulatory cells in the context of immune checkpoint blockade (2020) (76)
- Propionibacterium-Produced Coproporphyrin III Induces Staphylococcus aureus Aggregation and Biofilm Formation (2014) (76)
- Depletion of microbiome-derived molecules in the host using Clostridium genetics (2018) (71)
- Trehalose Biosynthesis Promotes Pseudomonas aeruginosa Pathogenicity in Plants (2013) (70)
- A family of pyrazinone natural products from a conserved nonribosomal peptide synthetase in Staphylococcus aureus. (2010) (69)
- Prokaryotic gene clusters: A rich toolbox for synthetic biology (2010) (69)
- Antibiotics from microbes: converging to kill. (2009) (67)
- A protein interaction surface in nonribosomal peptide synthesis mapped by combinatorial mutagenesis and selection. (2006) (65)
- Mammalian Lipopolysaccharide Receptors Incorporated into the Retroviral Envelope Augment Virus Transmission. (2015) (64)
- Molecular analysis of model gut microbiotas by imaging mass spectrometry and nanodesorption electrospray ionization reveals dietary metabolite transformations. (2012) (63)
- Biosynthetic tailoring of microcin E492m: post-translational modification affords an antibacterial siderophore-peptide conjugate. (2007) (61)
- Activity screening of carrier domains within nonribosomal peptide synthetases using complex substrate mixtures and large molecule mass spectrometry. (2006) (59)
- Genome-Directed Lead Discovery: Biosynthesis, Structure Elucidation, and Biological Evaluation of Two Families of Polyene Macrolactams against Trypanosoma brucei. (2015) (56)
- A Cutibacterium acnes antibiotic modulates human skin microbiota composition in hair follicles (2020) (54)
- Draft Genome Sequence of Streptomyces clavuligerus NRRL 3585, a Producer of Diverse Secondary Metabolites (2010) (52)
- Localized protein interaction surfaces on the EntB carrier protein revealed by combinatorial mutagenesis and selection. (2006) (48)
- MetaQuery: a web server for rapid annotation and quantitative analysis of specific genes in the human gut microbiome (2015) (48)
- Molecular insights into the biosynthesis of guadinomine: a type III secretion system inhibitor. (2012) (47)
- Expansion of RiPP biosynthetic space through integration of pan-genomics and machine learning uncovers a novel class of lantibiotics. (2020) (43)
- Enzymatic tailoring of enterobactin alters membrane partitioning and iron acquisition. (2006) (43)
- Key Applications of Plant Metabolic Engineering (2014) (42)
- Observing the invisible through imaging mass spectrometry, a window into the metabolic exchange patterns of microbes. (2012) (41)
- Endogenous retroviruses promote homeostatic and inflammatory responses to the microbiota (2021) (41)
- Gut microbes impact stroke severity via the trimethylamine N-oxide pathway. (2021) (41)
- Bile acids profile, histopathological indices and genetic variants for non-alcoholic fatty liver disease progression. (2020) (40)
- Structural characterization of enterobactin hydrolase IroE. (2006) (39)
- Total Biosynthesis: in vitro Reconstitution of Polyketide and Nonribosomal Peptide Pathways (2008) (39)
- The Biosynthesis of Lipooligosaccharide from Bacteroides thetaiotaomicron (2018) (35)
- Dapdiamides, Tripeptide Antibiotics Formed by Unconventional Amide Ligases† (2009) (34)
- Repurposing libraries of eukaryotic protein kinase inhibitors for antibiotic discovery (2009) (33)
- New ways to squash superbugs. (2009) (30)
- Quantification of bile acids: a mass spectrometry platform for studying gut microbe connection to metabolic diseases[S] (2019) (29)
- The gutSMASH web server: automated identification of primary metabolic gene clusters from the gut microbiota (2021) (21)
- Design, construction, and in vivo augmentation of a complex gut microbiome (2022) (21)
- Directing Biosynthesis (2006) (19)
- Specific biochemical inactivation of oncogenic Ras proteins by nucleoside diphosphate kinase. (2003) (19)
- Bacterially Derived Tryptamine Increases Mucus Release by Activating a Host Receptor in a Mouse Model of Inflammatory Bowel Disease (2020) (17)
- The next frontier of systems biology: higher-order and interspecies interactions (2010) (17)
- Recovery of the Gut Microbiota after Antibiotics Depends on Host Diet, Community Context, and Environmental Reservoirs. (2020) (16)
- A method for detection of SARS-CoV-2 RNA in healthy human stool: a validation study (2021) (16)
- esized and post-translationally modi fi ed peptide natural products : overview and recommendations for a universal nomenclature (2012) (15)
- Erratum: Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature (Natural Product Reports (2013) 30 (108-160) DOI:10.1039/C2NP20085F) (2013) (15)
- Inhibitors of sterol biosynthesis as Staphylococcus aureus antibiotics. (2008) (14)
- Bile acid metabolites control TH17 and Treg cell differentiation (2019) (13)
- Author Correction: Bile acid metabolites control TH17 and Treg cell differentiation (2020) (13)
- Cutibacterium acnes antibiotic production shapes niche competition in the human skin microbiome (2019) (12)
- Assembly‐Line Enzymology for Polyketide and Nonribosomal Peptide Antibiotics: Logic, Machinery, and Mechanisms (2006) (12)
- A Phase-Variable Surface Layer from the Gut Symbiont Bacteroides thetaiotaomicron (2015) (11)
- A systematic analysis of metabolic pathways in the human gut microbiota (2021) (11)
- Characterization of serine hydrolases across clinical isolates of commensal skin bacteria Staphylococcus epidermidis using activity-based protein profiling. (2020) (10)
- Bromoenterobactins as potent inhibitors of a pathogen-associated, siderophore-modifying C-glycosyltransferase. (2006) (9)
- BiG-MAP: an Automated Pipeline To Profile Metabolic Gene Cluster Abundance and Expression in Microbiomes (2020) (9)
- Recovery of the gut microbiota after antibiotics depends on host diet and environmental reservoirs (2019) (8)
- In vivo augmentation of a complex gut bacterial community (2021) (7)
- Decoding commensal-host communication through genetic engineering of Staphylococcus epidermidis (2019) (7)
- Impact of a 7-day homogeneous diet on interpersonal variation in human gut microbiomes and metabolomes. (2022) (7)
- Systematic dissection of a complex gut bacterial community (2021) (7)
- Computational genomic discovery of diverse gene clusters harbouring Fe-S flavoenzymes in anaerobic gut microbiota (2020) (5)
- Regulation of the nucleotide state of oncogenic ras proteins by nucleoside diphosphate kinase. (2006) (5)
- Erratum: Skin microbiota–host interactions (2018) (5)
- Validation and testing of a method for detection of SARS-CoV-2 RNA in healthy human stool (2020) (4)
- New Ways to Squash Superbugs: Scientists are using new tools and tactics in the race to discover novel antibiotics (2009) (4)
- Mapping the T cell repertoire to a complex gut bacterial community (2022) (3)
- Integration of machine learning and pan-genomics expands the biosynthetic landscape of RiPP natural products (2020) (3)
- Host-microbe co-metabolism via MCAD generates circulating metabolites including hippuric acid (2023) (2)
- Two distinct gut microbial pathways contribute to meta-organismal production of phenylacetylglutamine with links to cardiovascular disease. (2022) (2)
- Bacteroides thetaiotaomicron rough-type lipopolysaccharide: The chemical structure and the immunological activity. (2022) (2)
- Supervised topic modeling for predicting molecular substructure from mass spectrometry (2021) (2)
- CRISPR-based functional genomics in human dendritic cells (2020) (2)
- gutSMASH predicts specialized primary metabolic pathways from the human gut microbiota. (2023) (2)
- Identification of unique bile acid-metabolizing bacteria from the microbiome of centenarians (2020) (2)
- Strain dropouts reveal interactions that govern the metabolic output of the gut microbiome (2022) (2)
- A metabolomics pipeline enables mechanistic interrogation of the gut microbiome (2021) (2)
- Author response: CRISPR-based functional genomics in human dendritic cells (2021) (1)
- Bacillus subtilisA singular enzymatic megacomplex from Kolter (2007) (1)
- Eliciting a potent antitumor immune response by expressing tumor antigens in a skin commensal (2021) (1)
- Dyeing to learn more about the gut microbiota. (2013) (1)
- Natural Products: An Overview (2008) (1)
- Impact of a 7-day homogeneous diet on interpersonal variation in human gut microbiomes and metabolomes (2021) (1)
- tripeptide antibiotics formed by unconventional amide ligases. (2010) (1)
- Insights from a global view of secondary metabolism: Small molecules from the human microbiota (2015) (1)
- Gut commensal bacteria enhance pathogenesis of a tumorigenic murine retrovirus (2022) (1)
- Engineered skin bacteria induce antitumor T cell responses against melanoma (2023) (1)
- Production of an NKT cell stimulatory glycosphingolipid by a prominent member of the human gut microbiota (55.22) (2012) (1)
- Mycobacterium tuberculosis on the evolution of marinum Mycobacterium Insights from the complete genome sequence of Material Supplemental (2008) (0)
- Tryptamine Activates 5‐HT4 GPCR to Increase Secretion in the Mouse Proximal Colon (2018) (0)
- A Limited Effect of Chronic Renal Insufficiency on the Colon Microbiome. (2023) (0)
- -glycosyltransferase C characterization of IroB, a pathogen-associated In vitro From The Cover: (2006) (0)
- Qualitative model for the evolution of NRPS/PKS domains. (2014) (0)
- Large protein folds observed by NMR (2005) (0)
- 448 Understanding commensal-host communication through genetic engineering of Staphylococcus epidermidis (2019) (0)
- Computational genomic discovery of diverse gene clusters harboring Fe-S flavoenzymes in anaerobic gut microbiota (2020) (0)
- mutagenesis and selection A protein interaction surface in nonribosomal peptide synthesis mapped by combinatorial (2006) (0)
- Correction for ‘ ‘ HDAC 2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment (2009) (0)
- Correction for ‘‘Genome-wide expression profiling reveals distinct clusters of transcriptional regulation during bovine preimplantation development in vivo,’’ by W. A. Kues, S. Sud- (2009) (0)
- IMG-ABC: An Atlas of Biosynthetic Gene Clusters to Fuel the Discovery of Novel Secondary Metabolites (2014) (0)
- Identification of unique bile acid-metabolizing bacteria from the 1 microbiome of centenarians 2 3 (2020) (0)
- Decision letter: Microbiota functional activity biosensors for characterizing nutrient metabolism in vivo (2020) (0)
- GENERATION OF ANTIGEN-SPECIFIC REGULATORY T CELLS BYLACTOBACILLUS SPECIES (2022) (0)
- Resource Mapping the Genetic Landscape of Human Cells Graphical (2018) (0)
- Formation Aggregation and Biofilm Staphylococcus aureus Induces-Produced Coproporphyrin III Propionibacterium 2014 (2014) (0)
- Inhibitors of Sterol Biosynthesis as Staphylococcus aureus Antibiotics (2008) (0)
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What Schools Are Affiliated With Michael Fischbach?
Michael Fischbach is affiliated with the following schools:
