Michael Groll
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Researcher ORCID ID = 0000-0002-1660-340X
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Michael Grollcomputer-science Degrees
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Computer Science
Michael Groll's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science University of California, Berkeley
- Bachelors Computer Science University of California, Berkeley
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(Suggest an Edit or Addition)Michael Groll's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Structure of 20S proteasome from yeast at 2.4Å resolution (1997) (2245)
- A gated channel into the proteasome core particle (2000) (808)
- Crystal structure of the boronic acid-based proteasome inhibitor bortezomib in complex with the yeast 20S proteasome. (2006) (420)
- Immuno- and Constitutive Proteasome Crystal Structures Reveal Differences in Substrate and Inhibitor Specificity (2012) (416)
- Cleavage motifs of the yeast 20S proteasome beta subunits deduced from digests of enolase 1. (1998) (355)
- 20S proteasome and its inhibitors: crystallographic knowledge for drug development. (2007) (345)
- Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction (2008) (329)
- A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism (2008) (293)
- The catalytic sites of 20S proteasomes and their role in subunit maturation: a mutational and crystallographic study. (1999) (279)
- Crystal structures of Salinosporamide A (NPI-0052) and B (NPI-0047) in complex with the 20S proteasome reveal important consequences of beta-lactone ring opening and a mechanism for irreversible binding. (2006) (275)
- Contribution of Proteasomal β-Subunits to the Cleavage of Peptide Substrates Analyzed with Yeast Mutants* (1998) (263)
- Crystal Structure of Epoxomicin:20S Proteasome reveals a molecular basis for selectivity of alpha,beta-Epoxyketone Proteasome Inhibitors (2000) (261)
- The architecture of functional modules in the Hsp90 co‐chaperone Sti1/Hop (2012) (209)
- Marizomib, a proteasome inhibitor for all seasons: preclinical profile and a framework for clinical trials. (2011) (204)
- The 26S proteasome: assembly and function of a destructive machine. (2010) (198)
- Molecular Machines for Protein Degradation (2005) (195)
- Inhibitors of the eukaryotic 20S proteasome core particle: a structural approach. (2004) (190)
- Substrate access and processing by the 20S proteasome core particle. (2003) (184)
- Crystal structure of heat shock locus V (HslV) from Escherichia coli. (1997) (181)
- How an Inhibitor of the HIV-I Protease Modulates Proteasome Activity* (1999) (177)
- Crystal structure of the 20 S proteasome:TMC-95A complex: a non-covalent proteasome inhibitor. (2001) (168)
- RecA-like motor ATPases--lessons from structures. (2004) (160)
- Mechanism and Regulation of DNA-Protein Crosslink Repair by the DNA-Dependent Metalloprotease SPRTN (2016) (156)
- Induced-fit mechanism in class I terpene cyclases. (2014) (136)
- Proteasome beta-type subunits: unequal roles of propeptides in core particle maturation and a hierarchy of active site function. (1999) (121)
- Conformational constraints for protein self-cleavage in the proteasome. (1998) (120)
- Structure and function of Tim14 and Tim16, the J and J‐like components of the mitochondrial protein import motor (2006) (117)
- Inhibitors for the immuno- and constitutive proteasome: current and future trends in drug development. (2012) (116)
- Alternative bacterial two-component small heat shock protein systems (2012) (106)
- Probing the reaction mechanism of IspH protein by x-ray structure analysis (2009) (100)
- Spatial and temporal distribution of the dust deposition in Central Asia – results from a long term monitoring program (2013) (94)
- The Methylerythritol Phosphate Pathway to Isoprenoids. (2017) (93)
- Molecular shredders: how proteasomes fulfill their role. (2003) (92)
- Bivalency as a principle for proteasome inhibition. (1999) (91)
- Proteasome inhibition by fellutamide B induces nerve growth factor synthesis. (2008) (89)
- Synthetic and structural studies on syringolin A and B reveal critical determinants of selectivity and potency of proteasome inhibition (2009) (88)
- Crystal structure of the tricorn protease reveals a protein disassembly line (2001) (87)
- Investigations on the maturation and regulation of archaebacterial proteasomes. (2003) (87)
- Biochemistry of the non-mevalonate isoprenoid pathway (2011) (85)
- Functional and Phylogenetic Properties of the Pore-forming β-Barrel Transporters of the Omp85 Family* (2007) (84)
- A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome (2016) (82)
- Probing structural determinants distal to the site of hydrolysis that control substrate specificity of the 20S proteasome. (2002) (81)
- Covalent and non-covalent reversible proteasome inhibition (2012) (81)
- Good governance in international sport organizations: an analysis of the 35 Olympic sport governing bodies (2014) (80)
- Endometriosis and spontaneous abortion. (1984) (77)
- Incorporation of non-natural amino acids improves cell permeability and potency of specific inhibitors of proteasome trypsin-like sites. (2013) (76)
- Structure of active IspH enzyme from Escherichia coli provides mechanistic insights into substrate reduction. (2009) (76)
- Structure-based design of β1i or β5i specific inhibitors of human immunoproteasomes. (2014) (75)
- The proteasome. (1999) (73)
- The persisting challenge of selective and specific proteasome inhibition (2009) (73)
- TMC-95-based inhibitor design provides evidence for the catalytic versatility of the proteasome. (2006) (73)
- High-resolution structures of the IgM Fc domains reveal principles of its hexamer formation (2013) (72)
- Systematic comparison of peptidic proteasome inhibitors highlights the α-ketoamide electrophile as an auspicious reversible lead motif. (2014) (69)
- Tripeptide Mimetics Inhibit the 20 S Proteasome by Covalent Bonding to the Active Threonines* (2005) (69)
- The core structure of TMC-95A is a promising lead for reversible proteasome inhibition. (2002) (67)
- Crystal structure of TET protease reveals complementary protein degradation pathways in prokaryotes. (2005) (67)
- Thiazolopyrimidine Inhibitors of 2‐Methylerythritol 2,4‐Cyclodiphosphate Synthase (IspF) from Mycobacterium tuberculosis and Plasmodium falciparum (2010) (65)
- Biosynthesis of isoprenoids: crystal structure of the [4Fe-4S] cluster protein IspG. (2010) (65)
- The substrate translocation channel of the proteasome. (2001) (65)
- Bifunctional inhibitors of the trypsin-like activity of eukaryotic proteasomes. (1999) (63)
- 20S Proteasome and Its Inhibitors: Crystallographic Knowledge for Drug Development (2007) (63)
- Inhibitor-binding mode of homobelactosin C to proteasomes: new insights into class I MHC ligand generation. (2006) (62)
- Hydroxyureas as noncovalent proteasome inhibitors. (2012) (61)
- Bortezomib-resistant mutant proteasomes: structural and biochemical evaluation with carfilzomib and ONX 0914. (2015) (61)
- Syringolin A Selectively Labels the 20 S Proteasome in Murine EL4 and Wild‐Type and Bortezomib‐Adapted Leukaemic Cell Lines (2009) (61)
- Ferredoxin:NADPH oxidoreductase is recruited to thylakoids by binding to a polyproline type II helix in a pH-dependent manner (2010) (60)
- The structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins (2014) (60)
- Insights into Structural Network Responsible for Oligomerization and Activity of Bacterial Virulence Regulator Caseinolytic Protease P (ClpP) Protein* (2012) (58)
- Structural and functional insights into caseinolytic proteases reveal an unprecedented regulation principle of their catalytic triad (2013) (58)
- Hedycaryol Synthase in Complex with Nerolidol Reveals Terpene Cyclase Mechanism (2014) (56)
- Selective inhibition of the immunoproteasome by ligand-induced crosslinking of the active site. (2014) (55)
- Common Fibril Structures Imply Systemically Conserved Protein Misfolding Pathways In Vivo. (2017) (54)
- Diversity of proteasomal missions: fine tuning of the immune response (2007) (54)
- Exploiting nature's rich source of proteasome inhibitors as starting points in drug development. (2012) (54)
- Structure-based design of beta 1i or beta 5i specific inhibitors of human immunoproteasomes (2014) (54)
- Purification, crystallization, and X-ray analysis of the yeast 20S proteasome. (2005) (53)
- Peptido sulfonyl fluorides as new powerful proteasome inhibitors. (2012) (53)
- One-shot NMR analysis of microbial secretions identifies highly potent proteasome inhibitor (2012) (52)
- Aeolian dust deposition in the southern Aral Sea region (Uzbekistan): Ground-based monitoring results from the LUCA project (2017) (52)
- Inhibitors for the Immuno‐ and Constitutive Proteasome: Current and Future Trends in Drug Development (2012) (51)
- Structure of the Dioxygenase AsqJ: Mechanistic Insights into a One-Pot Multistep Quinolone Antibiotic Biosynthesis. (2016) (51)
- Pseudilins: halogenated, allosteric inhibitors of the non-mevalonate pathway enzyme IspD. (2014) (51)
- Convergent Synthesis and Biological Evaluation of Syringolin A and Derivatives as Eukaryotic 20S Proteasome Inhibitors (2010) (50)
- DNA minor groove sensing and widening by the CCAAT-binding complex. (2012) (50)
- Leaving groups prolong the duration of 20S proteasome inhibition and enhance the potency of salinosporamides. (2008) (50)
- Discovery of the First-in-Class Dual Histone Deacetylase-Proteasome Inhibitor. (2018) (48)
- The Chaperone Activity of the Developmental Small Heat Shock Protein Sip1 Is Regulated by pH-Dependent Conformational Changes. (2015) (47)
- Reverse fosmidomycin derivatives against the antimalarial drug target IspC (Dxr). (2011) (47)
- Structures of the tricorn‐interacting aminopeptidase F1 with different ligands explain its catalytic mechanism (2002) (46)
- ATP-induced Structural Transitions in PAN, the Proteasome-regulatory ATPase Complex in Archaea* (2007) (46)
- Proteasome structure, function, and lessons learned from beta-lactone inhibitors. (2011) (46)
- The Mammalian Proteasome Activator PA28 Forms an Asymmetric α4β3 Complex. (2017) (46)
- 20S Proteasome Inhibition: Designing Noncovalent Linear Peptide Mimics of the Natural Product TMC‐95A (2010) (44)
- Binding Mode of TMC‐95A Analogues to Eukaryotic 20S Proteasome (2004) (44)
- Crystal Structure of the Yersinia enterocolitica Type III Secretion Chaperone SycT* (2005) (43)
- Crystal structure of methylornithine synthase (PylB): insights into the pyrrolysine biosynthesis. (2012) (43)
- The natural product hybrid of Syringolin A and Glidobactin A synergizes proteasome inhibition potency with subsite selectivity. (2011) (42)
- Disruption of oligomerization and dehydroalanine formation as mechanisms for ClpP protease inhibition. (2014) (42)
- Innovative Trend Analysis of Precipitation in the Lake Issyk-Kul Basin, Kyrgyzstan (2020) (41)
- The CCAAT-binding complex (CBC) in Aspergillus species. (2017) (41)
- TMC‐95A Analogues with Endocyclic Biphenyl Ether Group as Proteasome Inhibitors (2004) (41)
- Quinone reductase acts as a redox switch of the 20S yeast proteasome (2009) (40)
- Synthesis of a TMC-95A ketomethylene analogue by cyclization via intramolecular Suzuki coupling. (2003) (40)
- Are free radicals involved in IspH catalysis? An EPR and crystallographic investigation. (2012) (40)
- Hydrops fetalis due to infantile Gaucher's disease. (1973) (40)
- Reversible Inhibitors Arrest ClpP in a Defined Conformational State that Can Be Revoked by ClpX Association. (2015) (39)
- Harnessing the evolvability of tricyclic microviridins to dissect protease-inhibitor interactions. (2014) (39)
- Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB (2018) (38)
- Crystal structures of mutant IspH proteins reveal a rotation of the substrate's hydroxymethyl group during catalysis. (2012) (38)
- Flavoenzyme-catalyzed formation of disulfide bonds in natural products. (2014) (37)
- Discovery of acetylene hydratase activity of the iron–sulphur protein IspH (2012) (36)
- Dimerized linear mimics of a natural cyclopeptide (TMC-95A) are potent noncovalent inhibitors of the eukaryotic 20S proteasome. (2013) (36)
- Potent proteasome inhibitors derived from the unnatural cis-cyclopropane isomer of Belactosin A: synthesis, biological activity, and mode of action. (2013) (35)
- Structural analysis of spiro beta-lactone proteasome inhibitors. (2008) (35)
- IspC as target for antiinfective drug discovery: synthesis, enantiomeric separation, and structural biology of fosmidomycin thia isosters. (2013) (35)
- Characterization of a Cyanobacterial Haloperoxidase and Evaluation of its Biocatalytic Halogenation Potential (2016) (33)
- Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors. (2015) (33)
- Snapshots of the fluorosalinosporamide/20S complex offer mechanistic insights for fine tuning proteasome inhibition. (2009) (32)
- An Uncommon Type II PKS Catalyzes Biosynthesis of Aryl Polyene Pigments. (2019) (31)
- Structure and mechanism of the caseinolytic protease ClpP1/2 heterocomplex from Listeria monocytogenes. (2015) (30)
- Elucidation of the α-keto-aldehyde binding mechanism: a lead structure motif for proteasome inhibition. (2011) (30)
- Impacts of dam draining on the mobility of heavy metals and arsenic in water and basin bottom sediments of three studied dams in Germany. (2018) (30)
- Menstrual function in Turner's syndrome. (1976) (29)
- Fatal amyloid formation in a patient’s antibody light chain is caused by a single point mutation (2020) (28)
- Land cover-adjusted index for the former Aral Sea using Landsat images (2021) (28)
- Macyranones: Structure, Biosynthesis, and Binding Mode of an Unprecedented Epoxyketone that Targets the 20S Proteasome. (2015) (28)
- Differential global structural changes in the core particle of yeast and mouse proteasome induced by ligand binding (2014) (27)
- System Dynamics Modeling of Water Level Variations of Lake Issyk-Kul, Kyrgyzstan (2017) (27)
- A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit β5i (2016) (27)
- Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor. (2014) (25)
- Indolo-phakellins as β5-specific noncovalent proteasome inhibitors. (2015) (25)
- Navigation inside a protease: substrate selection and product exit in the tricorn protease from Thermoplasma acidophilum. (2002) (25)
- Reductive dehydroxylation of allyl alcohols by IspH protein. (2010) (25)
- PINK1-dependent phosphorylation of Serine111 within the SF3 motif of Rab GTPases impairs effector interactions and LRRK2-mediated phosphorylation at Threonine72 (2019) (24)
- Changes in intra-annual runoff and its response to climate variability and anthropogenic activity in the Lake Issyk-Kul Basin, Kyrgyzstan (2020) (24)
- Selective Inhibition of the Immunoproteasome by Structure-Based Targeting of a Non-catalytic Cysteine. (2015) (23)
- Structures of fluoro, amino, and thiol inhibitors bound to the [Fe4S4] protein IspH. (2013) (23)
- Assessment of the distribution and activity of dunes in Iran based on mobility indices and ground data (2019) (23)
- Synthesis of bivalent inhibitors of eucaryotic proteasomes (2000) (23)
- The protease GtgE from Salmonella exclusively targets inactive Rab GTPases (2018) (22)
- Synthesis and Antiplasmodial Activity of Highly Active Reverse Analogues of the Antimalarial Drug Candidate Fosmidomycin (2010) (22)
- X-ray Snapshots of Peptide Processing in Mutants of Tricorn-interacting Factor F1 from Thermoplasma acidophilum* (2005) (22)
- Omuralide and vibralactone: differences in the proteasome- β-lactone-γ-lactam binding scaffold alter target preferences. (2014) (21)
- Catalytic mechanism and molecular engineering of quinolone biosynthesis in dioxygenase AsqJ (2018) (21)
- Insights into the Binding of Pyridines to the Iron–Sulfur Enzyme IspH (2014) (21)
- Applied techniques for mining natural proteasome inhibitors. (2014) (21)
- Synthesis and biological activity of optimized belactosin C congeners. (2011) (21)
- Status quo and present challenges of the sustainable use and management of water and land resources in Central Asian irrigation zones - The example of the Navoi region (Uzbekistan) (2017) (21)
- Analysing properties of proteasome inhibitors using kinetic and X-ray crystallographic studies. (2012) (20)
- Cryptic indole hydroxylation by a non-canonical terpenoid cyclase parallels bacterial xenobiotic detoxification (2017) (20)
- Structural snapshots of the minimal PKS system responsible for octaketide biosynthesis (2020) (20)
- Receptor-bound conformation of cilengitide better represented by its solution-state structure than the solid-state structure. (2014) (20)
- Activity enhancement of the synthetic syrbactin proteasome inhibitor hybrid and biological evaluation in tumor cells. (2012) (19)
- Gliotoxin Biosynthesis: Structure, Mechanism, and Metal Promiscuity of Carboxypeptidase GliJ. (2017) (19)
- Sequential Inactivation of Gliotoxin by the S-Methyltransferase TmtA. (2016) (17)
- Structural Elucidation of a Nonpeptidic Inhibitor Specific for the Human Immunoproteasome (2017) (17)
- The Co-chaperone Cns1 and the Recruiter Protein Hgh1 Link Hsp90 to Translation Elongation via Chaperoning Elongation Factor 2. (2019) (17)
- Identification and Experimental Characterization of an Extremophilic Brine Pool Alcohol Dehydrogenase from Single Amplified Genomes. (2017) (17)
- Structure-Based Design of β5c Selective Inhibitors of Human Constitutive Proteasomes. (2016) (17)
- A Predictive Approach for the Optical Control of Carbonic Anhydrase II Activity. (2018) (17)
- Estimation of soil erosion and sediment yield concentration across the Kolleru Lake catchment using GIS (2021) (16)
- A mass spectrometry platform for a streamlined investigation of proteasome integrity, posttranslational modifications, and inhibitor binding. (2015) (16)
- Engineering a Polyspecific Pyrrolysyl-tRNA Synthetase by a High Throughput FACS Screen (2019) (16)
- The Modern Problems of Sustainable Use and Management of Irrigated Lands on the Example of the Bukhara Region (Uzbekistan) (2015) (16)
- Azobenzene-based inhibitors of human carbonic anhydrase II (2015) (16)
- Global analysis of biosynthetic gene clusters reveals conserved and unique natural products in entomopathogenic nematode-symbiotic bacteria (2022) (16)
- Legionella effector AnkX displaces the switch II region for Rab1b phosphocholination (2020) (15)
- Structure-Based Design of Inhibitors Selective for Human Proteasome β2c or β2i Subunits (2019) (15)
- Selective activators of protein phosphatase 5 target the auto-inhibitory mechanism (2015) (15)
- Biosynthesis of the 22nd genetically encoded amino acid pyrrolysine: structure and reaction mechanism of PylC at 1.5Å resolution. (2012) (15)
- Mapping of Major Land-Use Changes in the Kolleru Lake Freshwater Ecosystem by Using Landsat Satellite Images in Google Earth Engine (2020) (14)
- Structural basis of HapEP88L-linked antifungal triazole resistance in Aspergillus fumigatus (2020) (14)
- Crystal Structure and Active Site Engineering of a Halophilic γ-Carbonic Anhydrase (2020) (13)
- Structural Basis for the Processive Protein Degradation by Tricorn Protease (2002) (13)
- Spatial and temporal variation of the aeolian sediment transport in the ephemeral Baringak Lake (Sistan Plain, Iran) using field measurements and geostatistical analyses (2018) (13)
- α‐Keto Phenylamides as P1′‐Extended Proteasome Inhibitors (2014) (13)
- The passive river restoration approach as an efficient tool to improve the hydromorphological diversity of rivers – Case study from two river restoration projects in the German lower mountain range (2017) (13)
- Molecular machines for protein degradation. Protein Degradation (2005) (13)
- A monodomain class II terpene cyclase assembles complex isoprenoid scaffolds (2020) (13)
- Versatile C(3)-symmetric scaffolds and their use for covalent stabilization of the foldon trimer. (2014) (13)
- Atomic-Resolution Structures of Discrete Stages on the Reaction Coordinate of the [Fe4S4] Enzyme IspG (GcpE). (2015) (12)
- Molecular mechanism of polyketide shortening in anthraquinone biosynthesis of Photorhabdus luminescens† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc00749k (2019) (12)
- The 19S cap puzzle: a new jigsaw piece. (2012) (12)
- Yersinia enterocolitica type III secretion chaperone SycH. Recombinant expression, purification, characterisation, and crystallisation. (2004) (12)
- The substrate translocation channel of the proteasome. (2001) (12)
- Identification of a β1/β2-specific sulfonamide proteasome ligand by crystallographic screening. (2015) (11)
- Mapping of Potential Groundwater Recharge Zones in the Kolleru Lake Catchment, India, by Using Remote Sensing and GIS Techniques (2020) (11)
- A Nut for Every Bolt: Subunit-Selective Inhibitors of the Immunoproteasome and Their Therapeutic Potential (2021) (11)
- Structural and Mechanistic Features of ClyA-Like α-Pore-Forming Toxins (2018) (10)
- Structure and reaction mechanism of pyrrolysine synthase (PylD). (2013) (10)
- Mechanism of Allosteric Inhibition of the Enzyme IspD by Three Different Classes of Ligands. (2017) (10)
- Functional Characterisation of ClpP Mutations Conferring Resistance to Acyldepsipeptide Antibiotics in Firmicutes (2020) (10)
- Rational Design of Proteasome Inhibitors as Antimalarial Drugs. (2016) (10)
- The Mammalian Proteasome Activator PA28 Forms an Asymmetric alpha 4 beta 3 Complex. (2017) (9)
- Good governance in International Non-Governmental Sports Organisations: an empirical study on accountability, participation and executive body members in Sport Governing Bodies (2013) (9)
- Iron Scavenging in Aspergillus Species: Structural and Biochemical Insights into Fungal Siderophore Esterases. (2018) (9)
- Defective immuno- and thymoproteasome assembly causes severe immunodeficiency (2018) (9)
- Interactions of the natural product kendomycin and the 20S proteasome. (2014) (8)
- CRYSTAL STRUCTURE OF THE 20S PROTEASOME FROM YEAST AT 2.4 ANGSTROMS RESOLUTION (1998) (8)
- Definition , Classification , Preservation and Dissemination of Traditional Sports & Games in Europe (2015) (8)
- Kristallstruktur der Methylornithin‐Synthase (PylB): Einblicke in die Biosynthese von Pyrrolysin (2012) (7)
- Investigation of Aeolian Dust Deposition Rates in Different Climate Zones of Southwestern Iran (2021) (7)
- Physical and Chemical Characterization of Dust Deposited in the Turan Lowland (Central Asia) (2019) (7)
- Evaluation of WRF-Chem Predictions for Dust Deposition in Southwestern Iran (2020) (7)
- Tunable Probes with Direct Fluorescence Signals for the Constitutive and Immunoproteasome. (2016) (7)
- Chemical Characterization of Aeolian Dust Deposition in Southern and Western Iran (2019) (6)
- Pathogenic bacteria remodel central metabolic enzyme to build a cyclopropanol warhead (2022) (6)
- Design of buried charged networks in artificial proteins (2021) (6)
- Causes and Effects of Sand and Dust Storms: What Has Past Research Taught Us? A Survey (2021) (6)
- Typology of Riverbed Structures and Habitats (TRiSHa) – A new method for a high resolution characterization of the spatial distribution and temporal dynamic of riverbed substrates and microhabitats (2016) (5)
- (−)-Homosalinosporamide A and Its Mode of Proteasome Inhibition: An X-ray Crystallographic Study (2018) (5)
- The Y. bercovieri Anbu crystal structure sheds light on the evolution of highly (pseudo)symmetric multimers (2017) (5)
- Design, synthesis, and evaluation of cystargolide-based β-lactones as potent proteasome inhibitors. (2018) (5)
- Spatial and temporal gradients in the rate of dust deposition and aerosol optical thickness in southwestern Iran (2020) (5)
- Assessment of Water Quality of the Trans-Boundary Zarafshan River in the Territory of Uzbekistan (2013) (5)
- Activation, Structure, Biosynthesis and Bioactivity of Glidobactin‐like Proteasome Inhibitors from Photorhabdus laumondii (2021) (5)
- Lake-catchment interactions and their responses to hydrological extremes (2018) (5)
- A Robust and Versatile Host Protein for the Design and Evaluation of Artificial Metal Centers (2019) (5)
- UEFA Football Competitions as European Sites of Memory — Cups of Identity? (2015) (5)
- On the Trails of the Proteasome Fold: Structural and Functional Analysis of the Ancestral β-Subunit Protein Anbu. (2018) (5)
- Identification of Critical Diffuse Pollution Sources in an Ungauged Catchment by Using the Swat Model- A Case Study of Kolleru Lake, East Coast of India (2020) (4)
- Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits. (2019) (4)
- Cultural aspects of traditional sports and games (2015) (4)
- Reductive Dehydroxylation of Allyl Alcohols by IspH Protein (2011) (4)
- Crystal structure of the yeast 20S proteasome in complex with bortezomib (2006) (4)
- Structural and Mechanistic Insights into C−S Bond Formation in Gliotoxin (2021) (4)
- Robust and Versatile Host Protein for the Design and Evaluation of Artificial Metal Centers (2019) (3)
- Structural Analysis of Spiro β-Lactone Proteasome Inhibitors (2008) (3)
- Managing Central Asia’s Transboundary Rivers: Case Studies Of The Zarafshan (Tajikistan/Uzbekistan) And Tarim (Kyrgyzstan/China) Rivers (2015) (3)
- Relations between the microscale riverbed morphology and the macrozoobenthos – implications for the ecological quality assessment and the definition of reference conditions (2018) (3)
- Impact of the Aral Sea Syndrome - the Aralkum as a Man-Made Dust Source (2019) (3)
- Synthesis, Kinetic Characterization and X-Ray Analysis of Peptide Aldehydes as Inhibitors of the 20S Proteasomes from Thermoplasma acidophilum and Saccharomyces cerevisiae (1997) (3)
- Ecological, socio-economic and demographic analyses as prerequisites for sewage treatment problem solutions in rural areas. The case study of Dirlammen, Vogelsberg, Germany (2018) (2)
- How ATPases unravel a mystery. (2009) (2)
- The formation of pyrroline and tetrahydropyridine rings in amino acids catalyzed by pyrrolysine synthase (PylD). (2014) (2)
- Ground-Based Dust Deposition Monitoring in the Aral Sea Basin (2021) (2)
- Good Governance in International Sports Organisations (2013) (2)
- Targeted Delivery of Proteasome Inhibitors to Somatostatin‐Receptor‐Expressing Cancer Cells by Octreotide Conjugation (2015) (2)
- Lawrence Berkeley National Laboratory Recent Work Title Mechanism and Regulation of DNA-Protein Crosslink Repair by the DNA-Dependent Metalloprotease (2)
- A Minimal beta-Lactone Fragment for Selective beta 5c or beta 5i Proteasome Inhibitors. (2015) (2)
- Inhibitors of the eukaryotic 20S proteasome core particle: a structural approach (2005) (1)
- Good Governance in International Non-Governmental Sport Organisations: An analysis based on empirical data on accountability, participation and executive body members in Sport Governing Bodies (2013) (1)
- Engineering a promiscuous pyrrolysyl-tRNA synthetase by a high throughput FACS screen (2017) (1)
- Mouse constitutive 20S proteasome (2012) (1)
- Cover Picture: Crystal Structure of Methylornithine Synthase (PylB): Insights into the Pyrrolysine Biosynthesis (Angew. Chem. Int. Ed. 6/2012) (2012) (1)
- Structural insights into cooperative DNA recognition by the CCAAT-binding complex and its bZIP transcription factor HapX. (2022) (1)
- Genetically Encoded Biotin Analogues: Incorporation and Application in Bacterial and Mammalian Cells (2019) (1)
- Proteasome Inhibitors in Experimental Cardiac Transplantation (2015) (1)
- The Chaperone Activity of the Developmental Small Heat Shock Protein Sip 1 Is Regulated by pH-Dependent Conformational Changes Graphical (2015) (1)
- Corrigendum to “Crystal Structure of TET Protease Reveals Complementary Protein Degradation Pathways in Prokaryotes” [J. Mol. Biol. (2005) 346, 1207–1219] (2005) (1)
- Cyclic biphenyl ether tripeptides as proteasome inhibitors (2003) (1)
- Crystal structure of the tricorn protease (2001) (1)
- Water resources in Central Asia - status quo and future conflicts in transboundary river catchments - the example of the Zarafshan River (Tajikistan-Uzbekistan) (2014) (1)
- Selinadiene Synthase in complex with dihydrofarnesyl pyrophosphate (2014) (1)
- Gonadotropic Patterns in Psychogenic Amenorrhea (1978) (1)
- Yeast 20S proteasome at 2.3 A resolution (2016) (1)
- Rat PP5 co-crystallized with P5SA-2 (2014) (1)
- A set of closely related methyltransferases for site-specific tailoring of anthraquinone pigments. (2023) (1)
- Crystal structure of ClpP from Staphylococcus aureus in the active, extended conformation (2012) (0)
- Yeast 20S proteasome in complex with the peptidic epoxyketone inhibitor 15 (2016) (0)
- Cooperative DNA base and shape recognition by the CCAAT-binding complex and its bZIP transcription factor HapX (2021) (0)
- The current status of international sports governance. Results of a test study by AGGIS-partners among international federations in 2012 (2013) (0)
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- Yeast 20S proteasome in complex with PR-957 (epoxide) (2012) (0)
- Stress-induced protein 1 from Caenorhabditis elegans (2015) (0)
- Yeast 20S proteasome beta2-H114D mutant (2015) (0)
- Glutathione-S-transferase GliG mutant N27A (2021) (0)
- Arabidopsis thaliana IspD Glu258Ala Mutant (2017) (0)
- Human Rab32:GDP in complex with Salmonella GtgE C45A mutant (2018) (0)
- Hsp17.7 from Deinococcus radiodurans (2012) (0)
- Inside Cover: Syringolin A Selectively Labels the 20 S Proteasome in Murine EL4 and Wild‐Type and Bortezomib‐Adapted Leukaemic Cell Lines (ChemBioChem 16/2009) (2009) (0)
- Yeast 20S proteasome with mouse beta5i (1-138) and mouse beta6 (97-111; 118-133) in complex with carfilzomib (2016) (0)
- Eukaryotic 20S Proteasome (2013) (0)
- Scientific ArticlesEndometriosis and spontaneous abortion (1985) (0)
- Yeast 20S proteasome in complex with Ac-PAE-ep (2015) (0)
- PylC in complex with D-ornithine and AMPPNP (2012) (0)
- Constitutive and immunoproteasome crystal structures reveal differences in substrate and inhibitor specificity (2012) (0)
- Ketosynthase (ApeO) in Complex with its Chain Length Factor (ApeC) from Xenorhabdus doucetiae (2019) (0)
- Structural and Biochemical Insights into Post-Translational Arginine-to-Ornithine Peptide Modifications by an Atypical Arginase (2023) (0)
- IspH:HMBPP (substrate) structure of the E126D mutant (2011) (0)
- yCP beta5-A49S-mutant in complex with bortezomib (2015) (0)
- Yeast 20S proteasome in complex with Ac-APLL-ep (2015) (0)
- Crystal structure of active site F1-mutant E213Q soaked with peptide Ala-Phe (2005) (0)
- A method for measuring a robot arm of an industrial robot (2010) (0)
- Gamma-Carbonic Anhydrase from the Haloarchaeon Halobacterium sp. (2020) (0)
- IspC in complex with an N-methyl-substituted hydroxamic acid (2011) (0)
- Crystal structure of 20S proteasome in complex with hydroxylated salinosporamide (2009) (0)
- Bovine trypsin in complex with microviridin J at pH 8.5 (2014) (0)
- Methyltransferase MtgA from Desulfitobacterium hafniense in complex with methyl-tetrahydrofolate (P212121) (2019) (0)
- Yeast 20S proteasome in complex with Ac-LAE-ep (2015) (0)
- CCAAT-binding complex from Aspergillus fumigatus with cycA DNA (2020) (0)
- Ec_IspH in complex with but-2-ynyl diphosphate (1086) (2012) (0)
- Identification and characterization of a novel proteasome inhibitor with apoptotic properties in neuroblastoma (2008) (0)
- Arabidopsis thaliana IspD in complex with pentabromo-pseudilin (2014) (0)
- AntF (apo): type II PKS acyl-carrier protein (2020) (0)
- Yeast 20S proteasome beta5-H(-2)A-T1A-K81R triple mutant in complex with Carfilzomib (2016) (0)
- PylD cocrystallized with L-Lysine-Ne-3S-methyl-L-ornithine and NAD+ (2014) (0)
- Yeast 20S proteasome with mouse beta5i (1-138) and mouse beta6 (97-111; 118-133) in complex with epoxyketone inhibitor 18 (2016) (0)
- Glutathione-S-transferase GliG in complex with cyclo[L-Phe-L-Ser]-bis-glutathione-adduct (2021) (0)
- Use of Landsat EVI in Determining the Degradation of Agroirriation Landscapes Adjacent to the Aydar-Arnasay Lakes System (2021) (0)
- Yeast 20S proteasome beta5-G48C mutant (2015) (0)
- 20S proteasome in complex with calpain-Inhibitor I from archaeoglobus fulgidus (2003) (0)
- Yeast 20S proteasome in complex with Ac-LAI-ep (2015) (0)
- Crystal structure of F1-mutant S105A complex with PRO-LEU-GLY-GLY (2005) (0)
- PylD cocrystallized with L-Ornithine-Nd-D-lysine and NAD+ (2014) (0)
- Structures in Tetrahydrofolate Methylation in Desulfitobacterial Glycine Betaine Metabolism at Atomic Resolution (2019) (0)
- High resolution NMR structure of the C mu3 domain from IgM (2013) (0)
- Yeast 20S proteasome in complex with Ac-LAF-ep (2015) (0)
- Yeast 20S proteasome in Complex with Kendomycin (2014) (0)
- Structure of Plasmodium IspC in complex with a beta-thia-isostere derivative of Fosmidomycin (2013) (0)
- Bortezomib and ONX0914 in Experimental Heart Transplantation (2016) (0)
- Human carboanhydrase F131C_C206S double mutant in complex with SA-2 (2017) (0)
- Human carbonic anhydrase II G132C_C206S double mutant in complex with SA-2 (2017) (0)
- Ligand-induced aziridine-formation at subunit beta5 of the yeast 20S proteasome (2014) (0)
- Yeast 20S proteasome in complex with Ac-LLL-ep (2015) (0)
- Structure of type II terpene cyclase MstE_D109N from Scytonema in complex with geranylgeranyl dihydroxybenzoate (substrate) (2020) (0)
- YaxB from Yersinia enterocolitica (2018) (0)
- Crystal Structure of the archaeal halo-thermophilic Red Sea brine pool alcohol dehydrogenase ADH/D1 bound to NADP (2017) (0)
- yCP beta5-C52F mutant in complex with Omuralide (2015) (0)
- Siderophore hydrolase EstB from Aspergillus fumigatus in complex with TAFC (2018) (0)
- yCP beta5-A49S mutant in complex with the epoxyketone inhibitor ONX 0914 (2015) (0)
- Test survey into the governance of certain international sports organisations (2012) (0)
- Yeast 20S proteasome with human beta2c (S171G) in complex with ONX 0914 (2019) (0)
- Glutathione-S-transferase GliG mutant E82A (2021) (0)
- Yeast 20S proteasome in complex with Ac-LAL-ep (2015) (0)
- A Dust Case Study of the Aral Sea Syndrome (2019) (0)
- Yeast 20S proteasome in complex with Ac-PAL-ep (2015) (0)
- Methyltransferase of the MtgA D102A mutant from Desulfitobacterium hafniense in complex with methyl-tetrahydrofolate (2019) (0)
- PylD cocrystallized with L-Ornithine-Nd-D-ornithine and NAD+ (2014) (0)
- Methyltransferase MtgA from Desulfitobacterium hafniense in complex with tetrahydrofolate (2019) (0)
- yCP in complex with Z-Leu-Leu-Leu-ketoaldehyde (2014) (0)
- SeMet-labeled PylC (remote) (2012) (0)
- Yeast 20S proteasome beta5-K33A mutant (propeptide expressed in trans) in complex with Carfilzomib (2016) (0)
- Structural determinants for 20S proteasome inhibition by TMC-95A (2005) (0)
- Method and system for testing the accuracy of a sensor (2008) (0)
- Arabidopsis thaliana IspD apo (2014) (0)
- Toward an understanding of the cellular role of yeast quinone reductase Lot6p (Vincent Massey Award Lecture) (2008) (0)
- Yeast 20S proteasome with human beta5i (1-138; V31M) and human beta6 (97-111; 118-133) in complex with epoxyketone inhibitor 17 (2016) (0)
- Rat PP5 apo (2014) (0)
- Ec_IspH in complex with 4-oxobutyl diphosphate (1302) (2012) (0)
- Siderophore hydrolase EstB from Aspergillus nidulans (2018) (0)
- Crystal structure of the yeast 20S proteasome in complex with ligand 2c (2011) (0)
- Crystal structure of yeast 20S proteasome in complex with the natural product carmaphycin A (2014) (0)
- Front Cover: Structures in Tetrahydrofolate Methylation in Desulfitobacterial Glycine Betaine Metabolism at Atomic Resolution (ChemBioChem 6/2020) (2020) (0)
- Exploiting Nature′s Rich Source of Proteasome Inhibitors as Starting Points in Drug Development (2012) (0)
- IspH in complex with 6-chloropyridin-3-ylmethyl diphosphate (2014) (0)
- Crystal structure of the yeast 20S proteasome in complex with syringolin B (2009) (0)
- Yeast 20S proteasome beta5-G48C mutant in complex with alpha-chloroacetamide 5 (2015) (0)
- PylD in complex with pyrroline-carboxy-lysine and NADH (2013) (0)
- Yeast 20S proteasome with human beta5c (1-138) and human beta6 (97-111; 118-133) in complex with epoxyketone inhibitor 16 (2016) (0)
- AntF (holo): type II PKS acyl-carrier protein (2020) (0)
- Heterocomplex structure of a polyketide synthase component involved in modular backbone halogenation. (2023) (0)
- Yeast 20S proteasome in complex with H-APLL-ep (2015) (0)
- The crystal structure of the mutant ClpP S98A (Staphylococcus aureus) (2012) (0)
- yCP in complex with Z-Leu-Leu-Leu-vinylsulfone (2014) (0)
- Yeast 20S proteasome with human beta5c (1-138) and human beta6 (97-111; 118-133) in complex with carfilzomib (2016) (0)
- Hsp90 co-chaperone Cns1 from Saccharomyces cerevisiae (delta69) (2019) (0)
- Solution structure of the yeast Sti1 DP2 domain (2012) (0)
- Siderophore hydrolase EstB mutant E211Q from Aspergillus fumigatus (2018) (0)
- Crystal structure of Vanadium-dependent Haloperoxidase from A. marina (2016) (0)
- Yeast 20S proteasome beta1-T1A beta2-T1A double mutant in complex with Carfilzomib (2016) (0)
- IgNAR antibody domain C2 (2014) (0)
- Yeast 20S proteasome in complex with the dimerized linear mimetic of TMC-95A - yCP:3a (2013) (0)
- PaxB from Photorhabdus luminescens (2018) (0)
- Yeast 20S proteasome in complex with 13 (2019) (0)
- ClpP2 from Listeria monocytogenes (2013) (0)
- yeast 20S proteasome in complex with the Syringolin-Glidobactin chimera (2012) (0)
- Fe(II)/(alpha)ketoglutarate-dependent dioxygenase AsqJ (2015) (0)
- Yeast 20S proteasome with human beta5c (1-138) and human beta6 (97-111; 118-133) (2016) (0)
- Crystal structure of active site F1-mutant E213Q soaked with peptide Pro-Leu-Gly-Gly (2005) (0)
- yCP in complex with Z-Leu-Leu-Leu-B(OH)2 (2014) (0)
- Yeast 20S proteasome beta7-delta7_Cter mutant (2015) (0)
- Yeast 20S proteasome in complex with N3-APnLL-ep (2015) (0)
- Evolution Inspired Engineering of Megasynthetases (2022) (0)
- Homobelactosin C bound to the yeast 20S proteasome (2006) (0)
- Crystal structure of the tetrahedral aminopeptidase from P. horikoshii (2005) (0)
- TPR2AB-domain:pHSP90-complex of yeast Sti1 (2012) (0)
- foldon domain wild type C-conjugate (2014) (0)
- yeast 20S proteasome:syringolin A-complex (2008) (0)
- Human Hsp90 co-chaperone TTC4 C-domain (2019) (0)
- Yeast 20S proteasome beta5-G48C mutant in complex with alpha-chloroacetamide 1 (2015) (0)
- Yeast 20S proteasome in complex with the peptidic non-covalent binding inhibitor RTS-V5 (2018) (0)
- Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB (2018) (0)
- Molecular assemblies of protein degradation pathways in prokaryotes and eukaryotes (2007) (0)
- Yeast 20S proteasome in complex with 20 (2019) (0)
- yCP in complex with MG132 (2014) (0)
- Human Rab8a phosphorylated at Ser111 in complex with GPPNP (2020) (0)
- 'Yeast 20S proteasome with human beta5i (1-138; V31M) and human beta6 (97-111; 118-133) in complex with epoxyketone inhibitor 18 (2016) (0)
- tricorn protease in complex with a tridecapeptide chloromethyl ketone derivative (2002) (0)
- PylD in complex with L-lysine-Ne-D-ornithine and NADH (2013) (0)
- Glutathione-S-transferase GliG with partially disordered active site (2021) (0)
- Titelbild: Kristallstruktur der Methylornithin‐Synthase (PylB): Einblicke in die Biosynthese von Pyrrolysin (Angew. Chem. 6/2012) (2012) (0)
- IspH:HMBPP complex structure of E126Q mutant (2011) (0)
- Spotlights on our sister journals: ChemistryOpen 1/2014 (2014) (0)
- Front Cover: Activation, Structure, Biosynthesis and Bioactivity of Glidobactin‐like Proteasome Inhibitors from Photorhabdus laumondii (ChemBioChem 9/2021) (2021) (0)
- Glutathione-S-transferase GliG mutant K127R (2021) (0)
- CRYSTAL STRUCTURE OF HSLV (CLPQ) AT 3.8 ANGSTROMS RESOLUTION (1998) (0)
- Defective immuno- and thymoproteasome assembly causes severe immunodeficiency (2018) (0)
- Yeast 20S proteasome beta5-T1A mutant in complex with Syringolin A, propeptide expressed in trans (2016) (0)
- Crystal structure of yeast 20S proteasome in complex with ligand 2a (2011) (0)
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What Schools Are Affiliated With Michael Groll?
Michael Groll is affiliated with the following schools:
