Michael J. Quon
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Engineering Computer Science
Michael J. Quon's Degrees
- PhD Computer Science Stanford University
- Masters Electrical Engineering University of California, Berkeley
- Bachelors Computer Engineering University of California, Berkeley
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(Suggest an Edit or Addition)Michael J. Quon's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans. (2000) (3598)
- Reciprocal Relationships Between Insulin Resistance and Endothelial Dysfunction: Molecular and Pathophysiological Mechanisms (2006) (1546)
- Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage. (2008) (1313)
- Adiponectin Stimulates Production of Nitric Oxide in Vascular Endothelial Cells* (2003) (998)
- Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells. (1996) (770)
- Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells. (2000) (756)
- Cardiovascular actions of insulin. (2007) (755)
- Serine Phosphorylation of Insulin Receptor Substrate 1 by Inhibitor κB Kinase Complex* 210 (2002) (651)
- Amyloid beta oligomers induce impairment of neuronal insulin receptors (2008) (566)
- New insights into the mechanisms of polyphenols beyond antioxidant properties; lessons from the green tea polyphenol, epigallocatechin 3-gallate (2014) (564)
- Insulin-stimulated Activation of eNOS Is Independent of Ca2+ but Requires Phosphorylation by Akt at Ser1179 * (2001) (537)
- Brain Insulin Receptors and Spatial Memory (1999) (519)
- Insulin and the insulin receptor in experimental models of learning and memory. (2004) (466)
- Leptin and Cardiovascular Disease: Response to Therapeutic Interventions (2008) (431)
- Serine phosphorylation of insulin receptor substrate 1 by inhibitor kappa B kinase complex. (2002) (393)
- High Density Lipoprotein-induced Endothelial Nitric-oxide Synthase Activation Is Mediated by Akt and MAP Kinases* (2003) (385)
- Inflammatory markers and the metabolic syndrome: insights from therapeutic interventions. (2005) (365)
- Repeatability characteristics of simple indices of insulin resistance: implications for research applications. (2001) (364)
- EGCG, a green tea polyphenol, improves endothelial function and insulin sensitivity, reduces blood pressure, and protects against myocardial I/R injury in SHR. (2007) (361)
- Physiological role of Akt in insulin-stimulated translocation of GLUT4 in transfected rat adipose cells. (1997) (354)
- Inhibition of Phosphatidylinositol 3-Kinase Enhances Mitogenic Actions of Insulin in Endothelial Cells* (2002) (353)
- Inhibition of insulin sensitivity by free fatty acids requires activation of multiple serine kinases in 3T3-L1 adipocytes. (2004) (350)
- Insulin stimulates both endothelin and nitric oxide activity in the human forearm. (1999) (303)
- Insulin resistance in spontaneously hypertensive rats is associated with endothelial dysfunction characterized by imbalance between NO and ET-1 production. (2005) (303)
- Epigallocatechin-3-gallate (EGCG), A Green Tea Polyphenol, Suppresses Hepatic Gluconeogenesis through 5′-AMP-activated Protein Kinase* (2007) (288)
- Use of bismannose photolabel to elucidate insulin-regulated GLUT4 subcellular trafficking kinetics in rat adipose cells. Evidence that exocytosis is a critical site of hormone action. (1993) (283)
- Additive Beneficial Effects of Losartan Combined With Simvastatin in the Treatment of Hypercholesterolemic, Hypertensive Patients (2004) (279)
- S6K Directly Phosphorylates IRS-1 on Ser-270 to Promote Insulin Resistance in Response to TNF-α Signaling through IKK2* (2008) (271)
- Aspirin Inhibits Serine Phosphorylation of Insulin Receptor Substrate 1 in Tumor Necrosis Factor-treated Cells through Targeting Multiple Serine Kinases* (2003) (266)
- Assessing the predictive accuracy of QUICKI as a surrogate index for insulin sensitivity using a calibration model. (2005) (256)
- Citrus polyphenol hesperidin stimulates production of nitric oxide in endothelial cells while improving endothelial function and reducing inflammatory markers in patients with metabolic syndrome. (2011) (237)
- Insulin receptor substrate-1 and phosphoinositide-dependent kinase-1 are required for insulin-stimulated production of nitric oxide in endothelial cells. (2002) (237)
- Adiponectin and Cardiovascular Disease (2007) (235)
- Molecular and physiologic actions of insulin related to production of nitric oxide in vascular endothelium (2003) (228)
- Mutations in the insulin receptor gene. (1992) (228)
- Protein Kinase C-ζ Phosphorylates Insulin Receptor Substrate-1 and Impairs Its Ability to Activate Phosphatidylinositol 3-Kinase in Response to Insulin* (2001) (226)
- Atorvastatin causes insulin resistance and increases ambient glycemia in hypercholesterolemic patients. (2010) (218)
- A mathematical model of metabolic insulin signaling pathways. (2002) (211)
- Epigallocatechin Gallate, a Green Tea Polyphenol, Mediates NO-dependent Vasodilation Using Signaling Pathways in Vascular Endothelium Requiring Reactive Oxygen Species and Fyn* (2007) (205)
- Insulin signalling: metabolic pathways and mechanisms for specificity. (1999) (204)
- Additive beneficial effects of fenofibrate combined with atorvastatin in the treatment of combined hyperlipidemia. (2005) (203)
- Caveolin-1 interacts with the insulin receptor and can differentially modulate insulin signaling in transfected Cos-7 cells and rat adipose cells. (1999) (195)
- FOXO1 Represses Peroxisome Proliferator-activated Receptor-γ1 and -γ2 Gene Promoters in Primary Adipocytes (2006) (188)
- Adiponectin and cardiovascular disease: response to therapeutic interventions. (2007) (188)
- An integrated view of insulin resistance and endothelial dysfunction. (2008) (184)
- Beneficial effects of fenofibrate to improve endothelial dysfunction and raise adiponectin levels in patients with primary hypertriglyceridemia. (2005) (175)
- High-dose oral vitamin C partially replenishes vitamin C levels in patients with Type 2 diabetes and low vitamin C levels but does not improve endothelial dysfunction or insulin resistance. (2006) (170)
- Insulin action and insulin resistance in vascular endothelium (2007) (170)
- Paternal versus maternal transmission of a stimulatory G-protein alpha subunit knockout produces opposite effects on energy metabolism. (2000) (165)
- Limitations of the fasting glucose to insulin ratio as an index of insulin sensitivity. (2001) (161)
- The Mouse obese Gene (1995) (160)
- Comparison between surrogate indexes of insulin sensitivity/resistance and hyperinsulinemic euglycemic clamp estimates in rats. (2008) (159)
- Cocoa consumption for 2 wk enhances insulin-mediated vasodilatation without improving blood pressure or insulin resistance in essential hypertension. (2008) (158)
- Regulation of leptin promoter function by Sp1, C/EBP, and a novel factor. (1998) (150)
- Roles of 1-phosphatidylinositol 3-kinase and ras in regulating translocation of GLUT4 in transfected rat adipose cells (1995) (149)
- Vascular and Metabolic Effects of Combined Therapy With Ramipril and Simvastatin in Patients With Type 2 Diabetes (2005) (147)
- Insulin receptor substrate 1 mediates the stimulatory effect of insulin on GLUT4 translocation in transfected rat adipose cells. (1994) (137)
- Differential metabolic effects of distinct statins. (2011) (133)
- Phosphorylation of PTP1B at Ser(50) by Akt impairs its ability to dephosphorylate the insulin receptor. (2001) (130)
- Protein-tyrosine Phosphatases PTP1B and Syp Are Modulators of Insulin-stimulated Translocation of GLUT4 in Transfected Rat Adipose Cells* (1997) (130)
- Insulin Receptor Dysfunction Impairs Cellular Clearance of Neurotoxic Oligomeric Aβ* (2009) (130)
- FOXO1 represses peroxisome proliferator-activated receptor-gamma1 and -gamma2 gene promoters in primary adipocytes. A novel paradigm to increase insulin sensitivity. (2006) (129)
- SirT1 enhances survival of human osteoarthritic chondrocytes by repressing protein tyrosine phosphatase 1B and activating the insulin-like growth factor receptor pathway. (2010) (128)
- Peroxisome Proliferator-activated Receptor-γ Represses GLUT4 Promoter Activity in Primary Adipocytes, and Rosiglitazone Alleviates This Effect* (2003) (124)
- Diagnosing insulin resistance by simple quantitative methods in subjects with normal glucose metabolism. (2004) (123)
- Impaired insulin secretion in the Turner metabolic syndrome. (2004) (122)
- Differential metabolic effects of pravastatin and simvastatin in hypercholesterolemic patients. (2009) (121)
- Consequences of Lipid Droplet Coat Protein Downregulation in Liver Cells (2008) (120)
- Comparison between surrogate indexes of insulin sensitivity and resistance and hyperinsulinemic euglycemic clamp estimates in mice. (2008) (120)
- Modulation of adiponectin as a potential therapeutic strategy. (2014) (119)
- Non-Insulin-Mediated Glucose Disappearance in Subjects With IDDM: Discordance Between Experimental Results and Minimal Model Analysis (1994) (113)
- Fish oil supplementation improves endothelial function in normoglycemic offspring of patients with type 2 diabetes. (2009) (112)
- Protein Kinase C-ζ and Phosphoinositide-dependent Protein Kinase-1 Are Required for Insulin-induced Activation of ERK in Rat Adipocytes* (1999) (110)
- Ghrelin has novel vascular actions that mimic PI 3-kinase-dependent actions of insulin to stimulate production of NO from endothelial cells. (2007) (109)
- Dehydroepiandrosterone mimics acute actions of insulin to stimulate production of both nitric oxide and endothelin 1 via distinct phosphatidylinositol 3-kinase- and mitogen-activated protein kinase-dependent pathways in vascular endothelium. (2006) (106)
- Insulin action in vascular endothelium: potential mechanisms linking insulin resistance with hypertension (2000) (103)
- Treatment of Spontaneously Hypertensive Rats With Rosiglitazone and/or Enalapril Restores Balance Between Vasodilator and Vasoconstrictor Actions of Insulin With Simultaneous Improvement in Hypertension and Insulin Resistance (2006) (98)
- Dependence of insulin-stimulated glucose transporter 4 translocation on 3-phosphoinositide-dependent protein kinase-1 and its target threonine-410 in the activation loop of protein kinase C-zeta. (1999) (95)
- Distinct vascular and metabolic effects of different classes of anti-hypertensive drugs. (2010) (95)
- Tyr612 and Tyr632 in Human Insulin Receptor Substrate-1 Are Important for Full Activation of Insulin-Stimulated Phosphatidylinositol 3-Kinase Activity and Translocation of GLUT4 in Adipose Cells. (2001) (94)
- Green tea polyphenol epigallocatechin gallate reduces endothelin-1 expression and secretion in vascular endothelial cells: roles for AMP-activated protein kinase, Akt, and FOXO1. (2010) (93)
- Anti-inflammatory and metabolic effects of candesartan in hypertensive patients. (2006) (93)
- Beneficial vascular and metabolic effects of peroxisome proliferator-activated receptor-alpha activators. (2005) (93)
- Role of lipotoxicity in endothelial dysfunction. (2012) (90)
- Epigallocatechin gallate induces expression of heme oxygenase-1 in endothelial cells via p38 MAPK and Nrf-2 that suppresses proinflammatory actions of TNF-α. (2012) (89)
- The union of vascular and metabolic actions of insulin in sickness and in health. (2005) (88)
- Consequences of lipid droplet coat proteins down – regulation in liver cells : Abnormal lipid droplet metabolism and induction of insulin resistance (2008) (88)
- Does reversal of oxidative stress and inflammation provide vascular protection? (2008) (88)
- Tyrosine kinase-deficient mutant human insulin receptors (Met1153-->Ile) overexpressed in transfected rat adipose cells fail to mediate translocation of epitope-tagged GLUT4. (1994) (88)
- Mechanisms for food polyphenols to ameliorate insulin resistance and endothelial dysfunction: therapeutic implications for diabetes and its cardiovascular complications. (2013) (87)
- Tyr(612) and Tyr(632) in human insulin receptor substrate-1 are important for full activation of insulin-stimulated phosphatidylinositol 3-kinase activity and translocation of GLUT4 in adipose cells. (2001) (84)
- Vascular and Metabolic Actions of the Green Tea Polyphenol Epigallocatechin Gallate (2014) (78)
- Reciprocal relationships between abnormal metabolic parameters and endothelial dysfunction (2007) (74)
- Transfection of DNA into isolated rat adipose cells by electroporation: evaluation of promoter activity in transfected adipose cells which are highly responsive to insulin after one day in culture. (1993) (73)
- Phosphorylation of Critical Serine Residues in Gem Separates Cytoskeletal Reorganization from Down-Regulation of Calcium Channel Activity (2004) (73)
- Phosphorylation of Ser24 in the Pleckstrin Homology Domain of Insulin Receptor Substrate-1 by Mouse Pelle-like Kinase/Interleukin-1 Receptor-associated Kinase (2005) (72)
- PKC-zeta mediates insulin effects on glucose transport in cultured preadipocyte-derived human adipocytes. (2002) (71)
- Glucose activates protein kinase C-zeta /lambda through proline-rich tyrosine kinase-2, extracellular signal-regulated kinase, and phospholipase D: a novel mechanism for activating glucose transporter translocation. (2001) (68)
- Action of insulin receptor substrate-3 (IRS-3) and IRS-4 to stimulate translocation of GLUT4 in rat adipose cells. (1999) (68)
- Oral Glucosamine for 6 Weeks at Standard Doses Does Not Cause or Worsen Insulin Resistance or Endothelial Dysfunction in Lean or Obese Subjects (2006) (67)
- Escherichia coli K1 Internalization via Caveolae Requires Caveolin-1 and Protein Kinase Cα Interaction in Human Brain Microvascular Endothelial Cells* (2002) (66)
- Endothelial dysfunction in mice with streptozotocin-induced type 1 diabetes is opposed by compensatory overexpression of cyclooxygenase-2 in the vasculature. (2009) (65)
- Glucose Activates Mitogen-activated Protein Kinase (Extracellular Signal-regulated Kinase) through Proline-rich Tyrosine Kinase-2 and the Glut1 Glucose Transporter* (2000) (64)
- Okadaic acid activates atypical protein kinase C (zeta/lambda) in rat and 3T3/L1 adipocytes. An apparent requirement for activation of Glut4 translocation and glucose transport. (1999) (64)
- Mouse 3-Phosphoinositide-dependent Protein Kinase-1 Undergoes Dimerization and trans-Phosphorylation in the Activation Loop* (2003) (63)
- Exenatide Treatment for 6 Months Improves Insulin Sensitivity in Adults With Type 1 Diabetes (2014) (63)
- Effects of overexpression of glutamine:fructose-6-phosphate amidotransferase (GFAT) and glucosamine treatment on translocation of GLUT4 in rat adipose cells (1997) (61)
- Overestimation of minimal model glucose effectiveness in presence of insulin response is due to undermodeling. (1998) (60)
- Cellular Stress, Excessive Apoptosis, and the Effect of Metformin in a Mouse Model of Type 2 Diabetic Embryopathy (2015) (58)
- Additive beneficial effects of fenofibrate combined with candesartan in the treatment of hypertriglyceridemic hypertensive patients. (2006) (58)
- Secretion of Annexin II via Activation of Insulin Receptor and Insulin-like Growth Factor Receptor* (2003) (57)
- Combination therapy for treatment or prevention of atherosclerosis: focus on the lipid-RAAS interaction. (2010) (56)
- Vasodilator response to systemic but not to local hyperinsulinemia in the human forearm. (1998) (56)
- Differential metabolic effects of rosuvastatin and pravastatin in hypercholesterolemic patients. (2010) (55)
- Additive beneficial cardiovascular and metabolic effects of combination therapy with ramipril and candesartan in hypertensive patients. (2006) (55)
- Negative regulation of insulin-stimulated mitogen-activated protein kinase signaling by Grb10. (2004) (54)
- Cyclic Nucleotide Phosphodiesterase 3B Is a Downstream Target of Protein Kinase B and May Be Involved in Regulation of Effects of Protein Kinase B on Thymidine Incorporation in FDCP2 Cells1 (2000) (53)
- Sorbitol activates atypical protein kinase C and GLUT4 glucose transporter translocation/glucose transport through proline-rich tyrosine kinase-2, the extracellular signal-regulated kinase pathway and phospholipase D. (2002) (52)
- Significant differential effects of omega-3 fatty acids and fenofibrate in patients with hypertriglyceridemia. (2012) (50)
- C-Reactive Protein Inhibits Insulin Activation of Endothelial Nitric Oxide Synthase via the Immunoreceptor Tyrosine-Based Inhibition Motif of FcγRIIB and SHIP-1 (2009) (50)
- A novel T608R missense mutation in insulin receptor substrate-1 identified in a subject with type 2 diabetes impairs metabolic insulin signaling. (2003) (50)
- Insulin impairs endothelium-dependent vasodilation independent of insulin sensitivity or lipid profile. (2004) (50)
- Insulin Receptor Substrate-2 (IRS-2) Can Mediate the Action of Insulin to Stimulate Translocation of GLUT4 to the Cell Surface in Rat Adipose Cells* (1997) (49)
- The Luteinizing Hormone-releasing Hormone Inhibits the Anti-apoptotic Activity of Insulin-like Growth Factor-1 in Pituitary αT3 Cells by Protein Kinase Cα-mediated Negative Regulation of Akt* (2004) (48)
- The effects of simvastatin, losartan, and combined therapy on soluble CD40 ligand in hypercholesterolemic, hypertensive patients. (2007) (48)
- Vascular and metabolic effects of treatment of combined hyperlipidemia: focus on statins and fibrates. (2008) (48)
- Toll-like receptor 2 mediates high-fat diet-induced impairment of vasodilator actions of insulin. (2013) (47)
- Tumor Necrosis Factor-α Antagonism Improves Vasodilation During Hyperinsulinemia in Metabolic Syndrome (2008) (47)
- Deterioration of glucose homeostasis in type 2 diabetic patients one year after beginning of statins therapy. (2012) (47)
- Treatment of spontaneously hypertensive rats with rosiglitazone ameliorates cardiovascular pathophysiology via antioxidant mechanisms in the vasculature. (2009) (46)
- PKCδ-mediated IRS-1 Ser24 phosphorylation negatively regulates IRS-1 function (2006) (46)
- Dehydroepiandrosterone Stimulates Phosphorylation of FoxO1 in Vascular Endothelial Cells via Phosphatidylinositol 3-Kinase- and Protein Kinase A-dependent Signaling Pathways to Regulate ET-1 Synthesis and Secretion* (2008) (45)
- Substitution of isoleucine for methionine at position 1153 in the beta-subunit of the human insulin receptor. A mutation that impairs receptor tyrosine kinase activity, receptor endocytosis, and insulin action. (1992) (44)
- Evidence for several independent genetic variants affecting lipoprotein (a) cholesterol levels. (2015) (44)
- Vascular, metabolic, and inflammatory abnormalities in normoglycemic offspring of patients with type 2 diabetes mellitus. (2007) (43)
- A phosphotyrosyl mimetic peptide reverses impairment of insulin-stimulated translocation of GLUT4 caused by overexpression of PTP1B in rat adipose cells. (1999) (43)
- Protein Kinase A-α Directly Phosphorylates FoxO1 in Vascular Endothelial Cells to Regulate Expression of Vascular Cellular Adhesion Molecule-1 mRNA* (2010) (43)
- Assessing Insulin Sensitivity and Resistance in Humans (2015) (42)
- Insulin signal transduction pathways (1994) (41)
- Substitution of the Autophosphorylation Site Thr516with a Negatively Charged Residue Confers Constitutive Activity to Mouse 3-Phosphoinositide-dependent Protein Kinase-1 in Cells* (2002) (41)
- QUICKI is a useful and accurate index of insulin sensitivity. (2002) (41)
- MKR mice are resistant to the metabolic actions of both insulin and adiponectin: discordance between insulin resistance and adiponectin responsiveness. (2006) (41)
- Epigallocatechin-3-gallate (EGCG), A Green Tea Polyphenol, Suppresses Hepatic Gluconeogenesis through (2007) (41)
- Are statins effective for simultaneously treating dyslipidemias and hypertension? (2008) (41)
- Anticoagulant Use and Risk of Ischemic Stroke and Bleeding in Patients With Secondary Atrial Fibrillation Associated With Acute Coronary Syndromes, Acute Pulmonary Disease, or Sepsis. (2017) (41)
- Reciprocal relationships between insulin resistance and endothelial dysfunction: insights from therapeutic interventions. (2006) (41)
- Globular adiponectin counteracts VCAM-1-mediated monocyte adhesion via AdipoR1/NF-κB/COX-2 signaling in human aortic endothelial cells. (2011) (39)
- G(s)alpha deficiency in adipose tissue leads to a lean phenotype with divergent effects on cold tolerance and diet-induced thermogenesis. (2010) (37)
- ASK1 mediates the teratogenicity of diabetes in the developing heart by inducing ER stress and inhibiting critical factors essential for cardiac development. (2015) (36)
- Essential role for membrane lipid rafts in interleukin-1beta-induced nitric oxide release from insulin-secreting cells: potential regulation by caveolin-1+. (2005) (36)
- Improvement of vascular insulin sensitivity by downregulation of GRK2 mediates exercise-induced alleviation of hypertension in spontaneously hypertensive rats. (2013) (36)
- NIPPV: Prevalence, Approach and Barriers to Use at Canadian ALS Centres (2010) (35)
- Protein kinase C-zeta phosphorylates insulin receptor substrate-1, -3, and -4 but not -2: isoform specific determinants of specificity in insulin signaling. (2008) (35)
- Direct Evidence that Myocardial Insulin Resistance following Myocardial Ischemia Contributes to Post-Ischemic Heart Failure (2015) (34)
- B4GALNT3 expression predicts a favorable prognosis and suppresses cell migration and invasion via β₁ integrin signaling in neuroblastoma. (2011) (34)
- Potentially important considerations in choosing specific statin treatments to reduce overall morbidity and mortality. (2013) (33)
- PAX3/forkhead homolog in rhabdomyosarcoma oncoprotein activates glucose transporter 4 gene expression in vivo and in vitro. (2002) (32)
- Effects of fenofibrate therapy on circulating adipocytokines in patients with primary hypertriglyceridemia. (2011) (32)
- Insulin stimulates increased catalytic activity of phosphoinositide-dependent kinase-1 by a phosphorylation-dependent mechanism. (2001) (32)
- Overexpression of Protein Tyrosine Phosphatase-α (PTP-α) but not PTP-κ Inhibits Translocation of GLUT4 in Rat Adipose Cells (1999) (31)
- Effects of overexpressing wild-type and mutant PDGF receptors on translocation of GLUT4 in transfected rat adipose cells. (1996) (31)
- Substitution of glutamic acid for alanine 1135 in the putative "catalytic loop" of the tyrosine kinase domain of the human insulin receptor. A mutation that impairs proteolytic processing into subunits and inhibits receptor tyrosine kinase activity. (1993) (31)
- Combination Pravastatin and Valsartan Treatment Has Additive Beneficial Effects to Simultaneously Improve Both Metabolic and Cardiovascular Phenotypes Beyond That of Monotherapy With Either Drug in Patients With Primary Hypercholesterolemia (2013) (30)
- Direct comparison of standard and insulin modified protocols for minimal model estimation of insulin sensitivity in normal subjects. (1994) (29)
- Additive beneficial effects of atorvastatin combined with amlodipine in patients with mild-to-moderate hypertension. (2011) (28)
- GENOMIC ORGANIZATION, PROMOTER ACTIVITY, AND ACTIVATION BY CCAAT/ENHANCER-BINDING PROTEIN a* (1995) (28)
- Endothelial dysfunction due to selective insulin resistance in vascular endothelium: insights from mechanistic modeling. (2020) (28)
- Comparison between surrogate indexes of insulin sensitivity/resistance and hyperinsulinemic euglycemic glucose clamps in rhesus monkeys. (2011) (27)
- Characterization of a mutant GLUT4 lacking the N-glycosylation site: studies in transfected rat adipose cells. (1996) (26)
- Deletion of interleukin 1 receptor-associated kinase 1 (Irak1) improves glucose tolerance primarily by increasing insulin sensitivity in skeletal muscle (2017) (26)
- Postbinding characterization of five naturally occurring mutations in the human insulin receptor gene: impaired insulin-stimulated c-jun expression and thymidine incorporation despite normal receptor autophosphorylation. (1992) (24)
- PKCdelta-mediated IRS-1 Ser24 phosphorylation negatively regulates IRS-1 function. (2006) (24)
- Vascular and metabolic effects of candesartan: insights from therapeutic interventions (2006) (24)
- Overestimation of minimal model glucose effectiveness in presence of insulin response is due to undermodeling. (1998) (24)
- Combined therapy with ramipril and simvastatin has beneficial additive effects on tissue factor activity and prothrombin fragment 1+2 in patients with type 2 diabetes. (2007) (23)
- α2-Heremans Schmid Glycoprotein Inhibits Insulin-Stimulated Elk-1 Phosphorylation, But Not Glucose Transport, in Rat Adipose Cells1 (1998) (23)
- Caveats to aggressive lowering of lipids by specific statins. (2012) (21)
- Effects of simvastatin therapy on circulating adipocytokines in patients with hypercholesterolemia. (2011) (20)
- Mechanisms of hormone resistance: lessons from insulin‐resistant patients (1994) (20)
- Differential metabolic actions of specific statins: clinical and therapeutic considerations. (2014) (19)
- Role of pleckstrin homology domain in regulating membrane targeting and metabolic function of insulin receptor substrate 3. (2003) (19)
- Cyclic Nucleotide Phosphodiesterase 3B Is a Downstream Target of Protein Kinase B and May Be Involved in Regulation of Effects of Protein Kinase B on Thymidine Incorporation in FDCP2 Cells (2000) (18)
- Race affects the association of obesity measures with insulin sensitivity. (2019) (18)
- PTEN does not modulate GLUT4 translocation in rat adipose cells under physiological conditions. (2001) (18)
- Simvastatin Treatment Protects Myocardium in Noncoronary Artery Cardiac Surgery by Inhibiting Apoptosis Through miR-15a-5p Targeting (2018) (16)
- Combining Potent Statin Therapy with Other Drugs to Optimize Simultaneous Cardiovascular and Metabolic Benefits while Minimizing Adverse Events (2017) (16)
- Limited predictive ability of surrogate indices of insulin sensitivity/resistance in Asian-Indian men. (2010) (15)
- Advances in kinetic analysis of insulin-stimulated GLUT-4 translocation in adipose cells. (1994) (15)
- Infliximab therapy restores adiponectin expression in perivascular adipose tissue and improves endothelial nitric oxide-mediated vasodilation in mice with type 1 diabetes. (2016) (15)
- Dominant negative FADD dissipates the proapoptotic signalosome of the unfolded protein response in diabetic embryopathy. (2015) (15)
- Targeting converging therapeutic pathways to overcome hypertension. (2009) (14)
- Estrogen deprivation in primate pregnancy leads to insulin resistance in offspring. (2016) (13)
- Two mutant alleles of the insulin receptor gene in a family with a genetic form of insulin resistance: a 10 base pair deletion in exon 1 and a mutation substituting serine for asparagine-462 (1995) (11)
- Alpha2-Heremans Schmid glycoprotein inhibits insulin-stimulated Elk-1 phosphorylation, but not glucose transport, in rat adipose cells. (1998) (11)
- Overexpression of protein tyrosine phosphatase-alpha (PTP-alpha) but not PTP-kappa inhibits translocation of GLUT4 in rat adipose cells. (1999) (11)
- Okadaic Acid Activates Atypical Protein Kinase C (ζ/λ) in Rat and 3T3/L1 Adipocytes (1999) (10)
- Acute vascular and metabolic actions of the green tea polyphenol epigallocatechin 3-gallate in rat skeletal muscle. (2017) (10)
- Additive Beneficial Effects of Fenofibrate Combined with Atorvastatin in the Treatment of Patients with Combined Hyperlipidemia(Lipid Disorders 1 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society) (2005) (10)
- Extracellular conversion of adiponectin hexamers into trimers (2012) (10)
- Molecular and Cellular Aspects of Insulin Resistance: Implications for Diabetes (2003) (9)
- The importance of considering alternative or combination strategies for lowering LDL-C. (2009) (8)
- Insulin Signaling Pathways Regulating Translocation of GLUT4 (2005) (8)
- Hormone Signaling (2002) (8)
- Monocyte DPP4 Expression in Human Atherosclerosis Is Associated With Obesity and Dyslipidemia (2017) (8)
- Glucose Activates Protein Kinase C-ζ/λ through Proline-rich Tyrosine Kinase-2, Extracellular Signal-regulated Kinase, and Phospholipase D (2001) (7)
- Simple modeling allows prediction of steady-state glucose disposal rate from early data in hyperinsulinemic glucose clamps. (2010) (7)
- EFFECTS OF FENOFIBRATE THERAPY ON CIRCULATING ADIPOCYTOKINES IN PATIENTS WITH PRIMARY HYPERTRIGLYCERIDEMIA (2011) (7)
- Combination therapy for treatment or prevention of atherosclerosis. (2008) (6)
- Role of renin-angiotensin system blockades in reciprocal relationship between insulin resistance and endothelial dysfunction. (2010) (6)
- Dynamic changes in plasma proinsulin/insulin ratio during insulin secretion influence correlation between radioimmunoassay (RIA) and IMX measurements of insulin. (1999) (5)
- Insulin Action and Endothelial Function (2008) (5)
- α2-Heremans Schmid Glycoprotein Inhibits Insulin-Stimulated Elk-1 Phosphorylation, But Not Glucose Transport, in Rat Adipose Cells* * This work was supported in part by a Research Award grant from the American Diabetes Association (to M.J.Q.). (1998) (5)
- Distinct mechanisms for globular adiponectin that integrate vascular and metabolic actions of insulin to help maintain coordinated cardiovascular and glucose homeostasis. (2013) (4)
- When MINMOD Artifactually Interprets Strong Insulin Secretion as Weak Insulin Action (2021) (4)
- Phosphorylation of Ser 24 in the Pleckstrin Homology Domain of Insulin Receptor Substrate-1 by Mouse Pelle-like Kinase / Interleukin-1 Receptor-associated Kinase CROSS-TALK BETWEEN INFLAMMATORY SIGNALING AND INSULIN SIGNALING (2005) (4)
- Letter re: Limited accuracy of surrogates of insulin resistance during puberty in obese and lean children at risk for altered glucoregulation. (2005) (3)
- Insulin signaling and the link to endothelial dysfunction. (2003) (3)
- complicationsfor diabetes and its cardiovascular resistance and endothelial dysfunction: therapeutic Mechanisms for food polyphenols to ameliorate insulin (2013) (2)
- Insulin and Insulin-Like Growth Factor-1 Receptors and Signaling Pathways: Similarities and Differences (2002) (2)
- Preventive cardiologyAdditive Beneficial Effects of Fenofibrate Combined With Atorvastatin in the Treatment of Combined Hyperlipidemia (2005) (2)
- indexes? of glucose effectiveness and insulin sensitivity The hot IVGTT two-compartment minimal model: (2011) (2)
- SIMVASTATIN IMPROVES ENDOTHELIUM-DEPENDENT DILATION, BUT REDUCES ADIPONECTIN LEVELS AND INSULIN SENSITIVITY IN HYPERCHOLESTEROLEMIC PATIENTS (2010) (1)
- Local hyperinsulinemia increases endothelin activity in the human forearm circulation (1998) (1)
- INSULIN ACTION IN VASCULAR ENDOTHELIUM (2002) (1)
- Man shall not live by bread alone. (2015) (1)
- Table 1, Methods for Assessing Insulin Sensitivity and Resistance In Humans (2015) (1)
- Letter by Koh and Quon regarding article, "Evidence mandating earlier and more aggressive treatment of hypercholesterolemia". (2009) (1)
- Does Reversible AF Exist? Or is AF Just AF? (2018) (1)
- Is further research needed on glucosamine? (2007) (1)
- Obesity modifies the effects of the Asp905Tyr variant of PPP1R3A on risk of type 2 diabetes and insulin sensitivity (2007) (1)
- Effects of insulin resistance on flow: Mediated dilation of conduit vessels (2003) (1)
- COMBINATION THERAPY WITH PRAVASTATIN AND VALSARTAN HAS ADDITIVE EFFECTS TO IMPROVE METABOLIC PHENOTYPES OVER MONOTHERAPY IN PATIENTS WITH HYPERCHOLESTEROLEMIA (2013) (1)
- Novel Anti-inflammatory and Metabolic Effects of Candesartan In Hypertensive Patients(Hypertension, Clinical 7 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society) (2005) (0)
- PE-157 Significant Differential Metabolic Effects of Atorvastatin, Atorvastatin Combined with Amlodipine, and Amlodipine Therapy in Hypertensive Patients(Atherosclerosis, clinical(05)(IHD),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society) (2008) (0)
- PE-448 Significant Differential Effects of Anti-hypertensive Drugs on Plasma Adiponectin Levels In Hypertensive Patients(Hypertension, clinical-04, The 71st Annual Scientific Meeting of the Japanese Circulation Society) (2007) (0)
- Fenofibrate Improves Endothelial Function by Enhancing Insulin Sensitivity in Hypertriglyceridemic Patients(Lipid Disorders 1 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society) (2005) (0)
- Dipeptidyl Peptidase 4/Midline‐1 Axis Promotes T Lymphocyte Motility in Atherosclerosis (2023) (0)
- Significant Differential Metabolic Effects of Losartan and Simvastatin in Hypercholesterolemic, Hypertensive Patients(Diabetes/Obesity 4 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society) (2005) (0)
- SIGNIFICANT DIFFERENTIAL EFFECTS OF OMEGA-3 FATTY ACIDS AND FENOFIBRATE IN PATIENTS WITH HYPERTRIGLYCERIDEMIA (2012) (0)
- ATORVASTATIN WORSENS GLUCOSE METABOLISM AND INSULIN SENSITIVITY IN PATIENTS WITH METABOLIC SYNDROME/TYPE 2 DIABETES (2010) (0)
- LHRH inhibits the anti-apoptotic activity of IGF-1 in pituitary T3 cells by PKC -mediated negative regulation of Akt (2004) (0)
- The Luteinizing Hormone-releasing Hormone Inhibits the Anti-apoptotic Activity of Insulin-like Growth Factor-1 in Pituitary (cid:1) T3 Cells by Protein Kinase C (cid:1) -mediated Negative Regulation of Akt* □ S (2004) (0)
- in presence of insulin response is due to undermodeling Overestimation of minimal model glucose effectiveness (2011) (0)
- PE-356 Simvastatin Improves Flow-Mediated Dilation, but Reduces Adiponectin Levels and Insulin Sensitivity in Overweight Hypercholesterolemic Patients(Lipid disorders(03)(H),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society) (2008) (0)
- Pathophysiology of Hypertension Improvement of vascular insulin sensitivity by downregulation of GRK 2 mediates exercise-induced alleviation of hypertension in spontaneously hypertensive rats (2013) (0)
- Abstract 3623: Ramipril Combined with Candesartan Improves Vascular and Metabolic Responses to a Greater Extent Than Monotherapy In the Treatment of Hypertensive Patients (2006) (0)
- ATORVASTATIN WORSENS GLUCOSE METABOLISM AND INSULIN SENSITIVITY IN HYPERCHOLESTEROLEMIC PATIENTS (2010) (0)
- IRAK-1/IRS-1 Signaling Cross Talk in Human Skeletal Muscle—Role in Insulin Resistance (2018) (0)
- Predicted effects of hemoglobin A1c assay precision on a patient population distribution of serial hemoglobin A1c difference values. (2007) (0)
- 103 FISH OIL SUPPLEMENTATION IMPROVES ENDOTHELIAL FUNCTION IN NORMOGLYCEMIC OFFSPRING OF PATIENTS WITH TYPE 2 DIABETES (2008) (0)
- IL-1 Receptor Associated Kinase-1 (IRAK-1) Null Mice have Increased Glucose Tolerance and Insulin Sensitivity (2014) (0)
- two-compartment model underestimation: improved accuracy by a Bayesian I overestimation and S G Minimal model S (2011) (0)
- Abstract 3204: Direct Vascular Effects of Ghrelin to Improve Endothelial Function by Restoring the Endothelin/Nitric Oxide Balance in Patients with Central Obesity (2006) (0)
- Dipeptidyl Peptidase 4/Midline‐1 Axis Promotes T Lymphocyte Motility in Atherosclerosis (Adv. Sci. 9/2023) (2023) (0)
- Additive Beneficial Effects of Ramipril Combined with Simvastatin in the Treatment of Type II Diabetic Patients(Atherosclerosis, Clinical 14 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society) (2005) (0)
- Abstract 3927: Comparative Effects of Ramipril and Candesartan on Plasma Leptin and Resistin Levels In the Treatment of Hypertensive Patients (2006) (0)
- PE-393 Significant Differential Metabolic Effects of Pravastatin and Simvastatin in Hypercholesterolemic Patients(PE066,Diabetes 2 (H),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese Circulation Society) (2009) (0)
- Abstract 2461: Leptin Stimulates both Endothelin and Nitric Oxide Activity in the Human Forearm Circulation (2008) (0)
- nflammatory Markers and the Metabolic Syndrome nsights From Therapeutic Interventions (2016) (0)
- 922 SIGNIFICANT DIFFERENTIAL METABOLIC EFFECTS OF ROSUVASTATIN AND PRAVASTATIN IN HYPERCHOLESTEROLEMIC PATIENTS (2012) (0)
- PE-241 Comparative Metabolic Effects of Ramipril and Candesartan in the Treatment of Hypertensive Patients(Diabetes/Obesity/Metabolic syndrome-8 (H) PE41,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society) (2006) (0)
- Siginificant Differential Metabolic Effects of Fenofibrate and Atorvastatin in Patients with Combined Hyperlipidemia(Diabetes/Obesity 5 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society) (2005) (0)
- Editorial Board (1992) (0)
- Reply: Limitations of Administrative Data for Examining Secondary Atrial Fibrillation. (2018) (0)
- Abstract 14163: Pravastatin Combined with Valsartan Shows Additive Beneficial Vascular Effects in Patients with Hypercholesterolemia (2012) (0)
- Improved insulin sensitivity and reduced adiposity with aP2 driven TLR4 overexpression in transgenic mice (2013) (0)
- 5 Insulin and Insulin-Like Growth Factor-1 Receptors and Signaling Pathways : Similarities and Differences (0)
- Response to Comment on Sarkar et al. Exenatide Treatment for 6 Months Improves Insulin Sensitivity in Adults With Type 1 Diabetes. Diabetes Care 2014;37:666–670 (2014) (0)
- Transgenic mice with ectopic expression of constitutively active TLR4 in adipose tissues do not show impaired insulin sensitivity (2017) (0)
- PE-378 Efonidipine Simultaneously Improves Endothelial Function and Metabolic Parameters In Patients with Hypertension(Atherosclerosis, clinical-08, The 71st Annual Scientific Meeting of the Japanese Circulation Society) (2007) (0)
- PE-368 Amlodipine Improves Endothelial Function and Metabolic Parameters in Patients with Hypertension(PE062,Atherosclerosis (Clinical/Treatment) (IHD),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society) (2009) (0)
- Reply: Reversible or Provoked Atrial Fibrillation? The Devil in the Details. (2018) (0)
- Insulin Action: Molecular Mechanisms and Determinants of Specificity (2000) (0)
- Immunoreceptor Tyrosine-Based Inhibition Motif of Fc C-Reactive Protein Inhibits Insulin Activation of Endothelial Nitric Oxide Synthase via the Print (2009) (0)
- transfected rat adipose cells. ras in regulating translocation of GLUT4 in Roles of 1-phosphatidylinositol 3-kinase and (2013) (0)
- impairment of vasodilator actions of insulin Toll-like receptor 2 mediates high-fat diet-induced (2013) (0)
- OE-172 Ramipril Combined with Candesartan Improves Vascular and Metabolic Responses to Greater Extent Than Monotherapy In Treatment of Hypertensive Patients(Hypertension, clinical-02, The 71st Annual Scientific Meeting of the Japanese Circulation Society) (2007) (0)
- FRS-070 Additive Beneficial Effects of Atorvastatin Combined with Amlodipine Therapy In Hypertensive Patients(FRS14,New Aspects for Hypertension (H),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society) (2009) (0)
- from a two-compartment model Undermodeling affects minimal model indexes: insights (2011) (0)
- ANTICOAGULANT USE AND THE RISK OF THROMBOEMBOLISM AND BLEEDING IN PATIENTS WITH NEW ATRIAL FIBRILLATION FOLLOWING NON-CARDIAC SURGERY (2019) (0)
- We-P14:486 Epigallocatechin gallate reduces blood pressure, improves insulin sensitivity, and protects against myocardial ischemia/reperfusion injury in SHR (2006) (0)
- 1105-169 Vascular endothelin-1 activity correlates with low-density lipoprotein cholesterol levels, but not with insulin sensitivity in hypercholesterolemic patients (2004) (0)
- 209 SIGNIFICANT DIFFERENTIAL EFFECTS OF OMEGA-3 FATTY ACIDS AND FENOFIBRATE IN PATIENTS WITH HYPERTRIGLYCERIDEMIA (2012) (0)
- Insulin Signaling in Vascular Endothelium (2006) (0)
- Hyperinsulinemic Euglycemic Glucose Clamps in Rhesus Monkeys Comparison between Surrogate Indexes of Insulin Sensitivity/Resistance and (2011) (0)
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What Schools Are Affiliated With Michael J. Quon?
Michael J. Quon is affiliated with the following schools:
