Michael J. Welsh

Q: What Schools Are Affiliated With Michael J. Welsh

Michael J. Welsh is affiliated with the following schools: University of California, Berkeley, California Institute of Technology, University of Michigan, Vanderbilt University, Stanford University, Columbia College Chicago, Baylor College of Medicine, University of Iowa, University of California, San Francisco, Duke University

Michael J. Welsh 's AcademicInfluence.com Rankings

Michael J. Welsh

Physics

#2375

World Rank

#3524

Historical Rank

physics Degrees

Download Badge

Physics

Michael J. Welsh 's Degrees

Masters Physics Stanford University

Why Is Michael J. Welsh Influential?

(Suggest an Edit or Addition)

According to Wikipedia, Michael James Welsh is an American pulmonologist. He is the current Roy J. Carver Chair in Biomedical Research, the Professor of Internal Medicine in Pulmonary, Critical Care and Occupational Medicine at the Department of Internal Medicine, and the Director of Pappajohn Biomedical Institute, Roy J. and Lucille A. Carver College of Medicine, University of Iowa. He is also a professor at the Department of Neurosurgery, Department of Neurology, and Department of Molecular Physiology and Biophysics. He received the 2022 Shaw Prize in Life science and Medicine, together with Paul A. Negulescu, for their work that uncovered the etiology of cystic fibrosis and developed effective medications.

(See a Problem?)

Michael J. Welsh 's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms (2000) (1517)
Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis (1993) (1447)
Cellular and Molecular Barriers to Gene Transfer by a Cationic Lipid (*) (1995) (1322)
Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive (1992) (1254)
Cystic Fibrosis Airway Epithelia Fail to Kill Bacteria Because of Abnormal Airway Surface Fluid (1996) (1113)
Demonstration that CFTR is a chloride channel by alteration of its anion selectivity. (1991) (1060)
A component of innate immunity prevents bacterial biofilm development (2002) (1016)
Structure and function of the CFTR chloride channel. (1999) (970)
Neuroprotection in Ischemia Blocking Calcium-Permeable Acid-Sensing Ion Channels (2004) (953)
Disruption of the CFTR Gene Produces a Model of Cystic Fibrosis in Newborn Pigs (2008) (742)
Reduced Airway Surface pH Impairs Bacterial Killing in the Porcine Cystic Fibrosis Lung (2012) (713)
Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis (1993) (649)
Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel (1991) (621)
Motile Cilia of Human Airway Epithelia Are Chemosensory (2009) (620)
Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells (1990) (616)
The Acid-Activated Ion Channel ASIC Contributes to Synaptic Plasticity, Learning, and Memory (2002) (596)
Production of β-defensins by human airway epithelia (1998) (559)
Acid-sensing ion channels: advances, questions and therapeutic opportunities (2006) (530)
Generation of cAMP-activated chloride currents by expression of CFTR. (1991) (528)
The mammalian sodium channel BNC1 is required for normal touch sensation (2000) (493)
Nucleoside triphosphates are required to open the CFTR chloride channel (1991) (482)
Mutations in CFTR associated with mild-disease-form CI- channels with altered pore properties (1993) (473)
Cystic Fibrosis Pigs Develop Lung Disease and Exhibit Defective Bacterial Eradication at Birth (2010) (463)
Origins of cystic fibrosis lung disease. (2015) (442)
A C-terminal motif found in the beta2-adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na+/H+ exchanger regulatory factor family of PDZ proteins. (1998) (428)
Chronic hyperalgesia induced by repeated acid injections in muscle is abolished by the loss of ASIC3, but not ASIC1 (2003) (425)
Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na+ channel (1995) (412)
Adenovirus Fiber Disrupts CAR-Mediated Intercellular Adhesion Allowing Virus Escape (2002) (402)
Cyclic AMP-dependent protein kinase opens chloride channels in normal but not cystic fibrosis airway epithelium (1988) (398)
Acid-Sensing Ion Channel 1 Is Localized in Brain Regions with High Synaptic Density and Contributes to Fear Conditioning (2003) (397)
Basolateral Localization of Fiber Receptors Limits Adenovirus Infection from the Apical Surface of Airway Epithelia* (1999) (391)
Chloride and potassium channels in cystic fibrosis airway epithelia (1986) (383)
Segregation of receptor and ligand regulates activation of epithelial growth factor receptor (2003) (381)
Electrolyte transport by airway epithelia. (1987) (380)
Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system (2007) (380)
Crypts are the site of intestinal fluid and electrolyte secretion. (1982) (368)
Calcium and cAMP activate different chloride channels in the apical membrane of normal and cystic fibrosis epithelia. (1991) (368)
Extracellular acidosis increases neuronal cell calcium by activating acid-sensing ion channel 1a. (2004) (365)
Binding of Adeno-associated Virus Type 5 to 2,3-Linked Sialic Acid Is Required for Gene Transfer* (2001) (361)
Heteromultimers of DEG/ENaC subunits form H+-gated channels in mouse sensory neurons (2002) (355)
The Amygdala Is a Chemosensor that Detects Carbon Dioxide and Acidosis to Elicit Fear Behavior (2009) (352)
Synergistic and additive killing by antimicrobial factors found in human airway surface liquid. (2000) (347)
The DRASIC Cation Channel Contributes to the Detection of Cutaneous Touch and Acid Stimuli in Mice (2001) (340)
An in vitro model of differentiated human airway epithelia. Methods for establishing primary cultures. (2002) (336)
Effect of ATP-sensitive K+ channel regulators on cystic fibrosis transmembrane conductance regulator chloride currents (1992) (333)
Production of CFTR-null and CFTR-DeltaF508 heterozygous pigs by adeno-associated virus-mediated gene targeting and somatic cell nuclear transfer. (2008) (329)
Expression and characterization of the cystic fibrosis transmembrane conductance regulator (1990) (314)
Cloning and Expression of a Novel Human Brain Na Channel (*) (1996) (313)
Impaired mucus detachment disrupts mucociliary transport in a piglet model of cystic fibrosis (2014) (313)
Inactivation of a Pseudomonas aeruginosa quorum-sensing signal by human airway epithelia. (2004) (279)
The DRASIC Cation Channel Contributes to the Detection of Cutaneous Touch and Acid Stimuli in Mice (2002) (275)
cAMP stimulates bicarbonate secretion across normal, but not cystic fibrosis airway epithelia. (1992) (275)
Production of beta-defensins by human airway epithelia. (1998) (274)
The Two Nucleotide-binding Domains of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Have Distinct Functions in Controlling Channel Activity (*) (1995) (272)
Loss of CFTR chloride channels alters salt absorption by cystic fibrosis airway epithelia in vitro. (1998) (265)
Ripped Pocket and Pickpocket, Novel Drosophila DEG/ENaC Subunits Expressed in Early Development and in Mechanosensory Neurons (1998) (263)
Electrophysiological and Biochemical Evidence That DEG/ENaC Cation Channels Are Composed of Nine Subunits* (1998) (252)
Disruption of the beta subunit of the epithelial Na+ channel in mice: hyperkalemia and neonatal death associated with a pseudohypoaldosteronism phenotype. (1999) (249)
Effect of deleting the R domain on CFTR-generated chloride channels. (1991) (247)
Chloride channels in the apical membrane of normal and cystic fibrosis airway and intestinal epithelia. (1992) (245)
Identification and regulation of the cystic fibrosis transmembrane conductance regulator-generated chloride channel. (1991) (242)
Fear and panic in humans with bilateral amygdala damage (2013) (242)
Regulation of the testis sertoli cell by follicle stimulating hormone. (1980) (241)
Maturation and function of cystic fibrosis transmembrane conductance regulator variants bearing mutations in putative nucleotide-binding domains 1 and 2 (1991) (241)
Regulation of the cystic fibrosis transmembrane conductance regulator Cl- channel by specific protein kinases and protein phosphatases. (1993) (240)
Activity of abundant antimicrobials of the human airway. (1999) (239)
Airway acidification initiates host defense abnormalities in cystic fibrosis mice (2016) (239)
Restoring Cystic Fibrosis Transmembrane Conductance Regulator Function Reduces Airway Bacteria and Inflammation in People with Cystic Fibrosis and Chronic Lung Infections (2017) (235)
Localization of cystic fibrosis transmembrane conductance regulator in chloride secretory epithelia. (1992) (233)
Regulation by ATP and ADP of CFTR chloride channels that contain mutant nucleotide-binding domains. (1992) (233)
Calcium-dependent regulator protein: localization in mitotic apparatus of eukaryotic cells. (1978) (232)
Loss of Anion Transport without Increased Sodium Absorption Characterizes Newborn Porcine Cystic Fibrosis Airway Epithelia (2010) (231)
Abnormal regulation of ion channels in cystic fibrosis epithelia (1990) (227)
Membrane topology of the amiloride-sensitive epithelial sodium channel. (1994) (224)
Isolation, characterization, and localization of the inositol 1,4,5-trisphosphate receptor protein in Xenopus laevis oocytes. (1992) (223)
Cloning and expression of the beta- and gamma-subunits of the human epithelial sodium channel. (1995) (221)
The porcine lung as a potential model for cystic fibrosis. (2008) (221)
Characterization of human tracheal epithelial cells transformed by an origin-defective simian virus 40. (1988) (219)
Neuropeptide FF and FMRFamide Potentiate Acid-Evoked Currents from Sensory Neurons and Proton-Gated DEG/ENaC Channels (2000) (218)
Acid-sensing Ion Channel 2 (ASIC2) Modulates ASIC1 H+-activated Currents in Hippocampal Neurons* (2004) (216)
Safety and efficacy of repetitive adenovirus–mediated transfer of CFTR cDNA to airway epithelia of primates and cotton rats (1994) (213)
Cystic fibrosis transmembrane conductance regulator: A chloride channel with novel regulation (1992) (213)
Seizure termination by acidosis depends on ASIC1a (2008) (210)
An apical-membrane chloride channel in human tracheal epithelium. (1986) (206)
A Molecular Component of the Arterial Baroreceptor Mechanotransducer (1998) (205)
Overexpression of acid-sensing ion channel 1a in transgenic mice increases acquired fear-related behavior. (2004) (199)
Protons are a neurotransmitter that regulates synaptic plasticity in the lateral amygdala (2014) (197)
Enhanced Locomotion Caused by Loss of the Drosophila DEG/ENaC Protein Pickpocket1 (2003) (197)
The ΔF508 Mutation Causes CFTR Misprocessing and Cystic Fibrosis–Like Disease in Pigs (2011) (195)
Acid-sensing ion channel 1a is a postsynaptic proton receptor that affects the density of dendritic spines (2006) (187)
Cystic fibrosis decreases the apical membrane chloride permeability of monolayers cultured from cells of tracheal epithelium. (1985) (186)
Acidic pH increases airway surface liquid viscosity in cystic fibrosis. (2016) (184)
Identification of revertants for the cystic fibrosis ΔF508 mutation using STE6-CFTR chimeras in yeast (1993) (182)
Tubulin and calmodulin. Effects of microtubule and microfilament inhibitors on localization in the mitotic apparatus (1979) (181)
Development of cystic fibrosis and noncystic fibrosis airway cell lines. (2003) (179)
Loss of cystic fibrosis transmembrane conductance regulator function produces abnormalities in tracheal development in neonatal pigs and young children. (2010) (179)
Drosophila hygrosensation requires the TRP channels water witch and nanchung (2007) (174)
DEG/ENaC ion channels involved in sensory transduction are modulated by cold temperature (2001) (171)
Hormone-free mouse glucocorticoid receptors overexpressed in Chinese hamster ovary cells are localized to the nucleus and are associated with both hsp70 and hsp90. (1990) (171)
The Ion Channel ASIC2 Is Required for Baroreceptor and Autonomic Control of the Circulation (2009) (169)
pH modulates the activity and synergism of the airway surface liquid antimicrobials β-defensin-3 and LL-37 (2014) (168)
Heat shock protein 90-dependent (geldanamycin-inhibited) movement of the glucocorticoid receptor through the cytoplasm to the nucleus requires intact cytoskeleton. (1998) (167)
Contribution of Drosophila DEG/ENaC Genes to Salt Taste (2003) (167)
Abnormal localization of cystic fibrosis transmembrane conductance regulator in primary cultures of cystic fibrosis airway epithelia (1992) (164)
Small Heat‐Shock Protein Family: Function in Health and Disease (1998) (164)
Development and analysis of recombinant adenoviruses for gene therapy of cystic fibrosis. (1993) (163)
Identification and function of thermosensory neurons in Drosophila larvae (2003) (163)
Calcium‐activated potassium channels in canine airway smooth muscle. (1986) (163)
Breathing Inhibited When Seizures Spread to the Amygdala and upon Amygdala Stimulation (2015) (161)
Rat sertoli cells: a rapid method for obtaining viable cells. (1975) (161)
Cadmium in vivo causes disruption of tight junction-associated microfilaments in rat Sertoli cells. (1993) (158)
Ca2+-dependent regulator. Production and characterization of a monospecific antibody. (1978) (158)
Cloning, expression, and tissue distribution of a human amiloride-sensitive Na+ channel. (1994) (155)
The ion channel ASIC1 contributes to visceral but not cutaneous mechanoreceptor function. (2004) (153)
The Respiratory Epithelium (1986) (152)
Oxidants increase paracellular permeability in a cultured epithelial cell line. (1985) (152)
Acid-sensing ion channels contribute to synaptic transmission and inhibit cocaine-evoked plasticity (2014) (151)
Regulation of the cystic fibrosis transmembrane conductance regulator Cl- channel by negative charge in the R domain. (1993) (151)
Stimulation of CFTR activity by its phosphorylated R domain (1997) (150)
TRPA channels distinguish gravity sensing from hearing in Johnston's organ (2009) (145)
The sperm outer dense fiber protein is the 10th member of the superfamily of mammalian small stress proteins (2003) (145)
Number of Subunits Comprising the Epithelial Sodium Channel* (1999) (143)
Interactions between Subunits of the Human Epithelial Sodium Channel* (1997) (140)
Detecting activity-evoked pH changes in human brain (2012) (140)
A single low cadmium dose causes failure of spermiation in the rat. (1993) (139)
Antimicrobial peptides and proteins in the innate defense of the airway surface. (2001) (139)
Pathology of gastrointestinal organs in a porcine model of cystic fibrosis. (2010) (136)
HSP22, a New Member of the Small Heat Shock Protein Superfamily, Interacts with Mimic of Phosphorylated HSP27 (3DHSP27) (2001) (134)
Functional activation of the cystic fibrosis trafficking mutant delta F508-CFTR by overexpression. (1995) (133)
The osmolyte xylitol reduces the salt concentration of airway surface liquid and may enhance bacterial killing. (2000) (133)
Interaction of Human HSP22 (HSPB8) with Other Small Heat Shock Proteins* (2004) (130)
Gene transfer of CFTR to airway epithelia: low levels of expression are sufficient to correct Cl- transport and overexpression can generate basolateral CFTR. (2005) (130)
Evidence that the FK506-binding immunophilin heat shock protein 56 is required for trafficking of the glucocorticoid receptor from the cytoplasm to the nucleus. (1995) (129)
ppk23-Dependent Chemosensory Functions Contribute to Courtship Behavior in Drosophila melanogaster (2012) (129)
Antisense inhibition of glial S100 beta production results in alterations in cell morphology, cytoskeletal organization, and cell proliferation (1990) (128)
Podocyte alpha-actinin induction precedes foot process effacement in experimental nephrotic syndrome. (1997) (128)
Biochemical Basis of Touch Perception: Mechanosensory Function of Degenerin/Epithelial Na+ Channels* (2002) (127)
A severe phenotype in mice with a duplication of exon 3 in the cystic fibrosis locus. (1993) (126)
Stoichiometry of recombinant cystic fibrosis transmembrane conductance regulator in epithelial cells and its functional reconstitution into cells in vitro. (1994) (123)
Interaction of the synaptic protein PICK1 (protein interacting with C kinase 1) with the non-voltage gated sodium channels BNC1 (brain Na+ channel 1) and ASIC (acid-sensing ion channel). (2002) (122)
Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator Cl− Channel by Its R Domain* (2001) (122)
Effect of ATP concentration on CFTR Cl- channels: a kinetic analysis of channel regulation. (1994) (121)
Ca2+ and cyclic AMP in regulation of intestinal Na, K, and Cl transport. (1986) (119)
Identification and regulation of whole-cell chloride currents in airway epithelium (1989) (116)
Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs. (2013) (115)
The amino-terminal portion of CFTR forms a regulated CI− channel (1994) (115)
Lysozyme secretion by submucosal glands protects the airway from bacterial infection. (2005) (114)
Human cystic fibrosis airway epithelia have reduced Cl− conductance but not increased Na+ conductance (2011) (113)
Processing and function of CFTR-ΔF508 are species-dependent (2007) (112)
Gel-forming mucins form distinct morphologic structures in airways (2017) (112)
Regulation of Cl- and K+ channels in airway epithelium. (1990) (111)
Cystic Fibrosis-associated Mutations at Arginine 347 Alter the Pore Architecture of CFTR (1999) (110)
Chemosensory functions for pulmonary neuroendocrine cells. (2014) (109)
Cystic fibrosis transmembrane conductance regulator splice variants are not conserved and fail to produce chloride channels (1993) (108)
Localization of β and γ subunits of ENaC in sensory nerve endings in the rat foot pad (2000) (108)
Loss of Bardet–Biedl syndrome proteins alters the morphology and function of motile cilia in airway epithelia (2008) (107)
Evidence that the 90-kilodalton heat shock protein is associated with tubulin-containing complexes in L cell cytosol and in intact PtK cells. (1988) (107)
Chaperone functions of the heat shock proteins associated with steroid receptors. (1994) (107)
Inositol trisphosphate isomers, but not inositol 1,3,4,5-tetrakisphosphate, induce calcium influx in Xenopus laevis oocytes. (1988) (106)
Enhancing glycolysis attenuates Parkinson's disease progression in models and clinical databases. (2019) (105)
Molecular Biology of Membrane Transport Disorders (1996) (104)
A functional R domain from cystic fibrosis transmembrane conductance regulator is predominantly unstructured in solution. (2000) (104)
Expression of normal and cystic fibrosis phenotypes by continuous airway epithelial cell lines. (1990) (103)
Pigs and humans with cystic fibrosis have reduced insulin-like growth factor 1 (IGF1) levels at birth (2010) (101)
Fatty acids inhibit apical membrane chloride channels in airway epithelia. (1990) (101)
Drosophila DEG/ENaC pickpocket genes are expressed in the tracheal system, where they may be involved in liquid clearance (2003) (101)
ASIC2 Subunits Target Acid-Sensing Ion Channels to the Synapse via an Association with PSD-95 (2009) (100)
Inositol trisphosphate is required for the propagation of calcium waves in Xenopus oocytes. (1992) (99)
Curcumin Stimulates Cystic Fibrosis Transmembrane Conductance Regulator Cl– Channel Activity* (2005) (98)
Changes in either Cytosolic or Nucleoplasmic Inositol 1,4,5-Trisphosphate Levels Can Control Nuclear Ca2+ Concentration (*) (1995) (98)
ENaC Subunits Are Molecular Components of the Arterial Baroreceptor Complex (2001) (95)
Normal gating of CFTR requires ATP binding to both nucleotide-binding domains and hydrolysis at the second nucleotide-binding domain. (2005) (95)
Mechanism of dysfunction of two nucleotide binding domain mutations in cystic fibrosis transmembrane conductance regulator that are associated with pancreatic sufficiency. (1995) (94)
Effect of Cystic Fibrosis-associated Mutations in the Fourth Intracellular Loop of Cystic Fibrosis Transmembrane Conductance Regulator* (1996) (93)
A shortened adeno-associated virus expression cassette for CFTR gene transfer to cystic fibrosis airway epithelia. (2005) (93)
Normal sweat chloride values do not exclude the diagnosis of cystic fibrosis. (1995) (90)
HSP27 in signal transduction and association with contractile proteins in smooth muscle cells. (1999) (89)
Post-transcriptional regulation of cystic fibrosis transmembrane conductance regulator expression and function by microRNAs. (2013) (89)
Group D Adenoviruses Infect Primary Central Nervous System Cells More Efficiently than Those from Group C (1999) (89)
Development of a porcine model of cystic fibrosis. (2009) (88)
DRASIC contributes to pH-gated currents in large dorsal root ganglion sensory neurons by forming heteromultimeric channels. (2002) (87)
ASIC3 and ASIC1 mediate FMRFamide-related peptide enhancement of H+-gated currents in cultured dorsal root ganglion neurons. (2003) (87)
Defective fluid transport by cystic fibrosis airway epithelia. (1994) (86)
Voltage-dependent and Ca2(+)-activated ion channels in human neutrophils. (1990) (85)
The distribution of calmodulin in living mitotic cells. (1983) (85)
Fluid and electrolyte transport by cultured human airway epithelia. (1993) (84)
HSP27 expression regulates CCK-induced changes of the actin cytoskeleton in CHO-CCK-A cells. (1999) (84)
cAMP-dependent protein kinase phosphorylation of the acid-sensing ion channel-1 regulates its binding to the protein interacting with C-kinase-1 (2003) (84)
Interactions of HSP22 (HSPB8) with HSP20, αB-crystallin, and HSPB3 (2005) (83)
Regulation of CFTR Cl- channel gating by ATP binding and hydrolysis. (2000) (83)
Localization of epithelial sodium channel subunit mRNAs in adult rat lung by in situ hybridization. (1996) (83)
Ischemic acute renal failure induces differential expression of small heat shock proteins. (2000) (83)
rENaC is the predominant Na+ channel in the apical membrane of the rat renal inner medullary collecting duct. (1995) (82)
Overexpression of heat shock protein Hsp27 protects against cerulein-induced pancreatitis. (2004) (82)
Intracellular chloride activities in canine tracheal epithelium. Direct evidence for sodium-coupled intracellular chloride accumulation in a chloride-secreting epithelium. (1983) (81)
Immunofluorescence localization of the 90-kDa heat-shock protein to cytoskeleton. (1996) (80)
The hsp56 immunophilin component of untransformed steroid receptor complexes is localized both to microtubules in the cytoplasm and to the same nonrandom regions within the nucleus as the steroid receptor. (1994) (77)
Cystic fibrosis carriers are at increased risk for a wide range of cystic fibrosis-related conditions (2019) (76)
Protons Activate Brain Na+ Channel 1 by Inducing a Conformational Change That Exposes a Residue Associated with Neurodegeneration* (1998) (76)
Antibacterial properties of the CFTR potentiator ivacaftor. (2014) (76)
Intracellular calcium regulates basolateral potassium channels in a chloride-secreting epithelium. (1985) (76)
Interaction of the glucocorticoid receptor with the Mr 90,000 heat shock protein: an evolving model of ligand-mediated receptor transformation and translocation. (1989) (75)
Mutation of R555 in CFTR-delta F508 enhances function and partially corrects defective processing. (1996) (75)
Association of domains within the cystic fibrosis transmembrane conductance regulator. (1997) (75)
Protein phosphatase 2C dephosphorylates and inactivates cystic fibrosis transmembrane conductance regulator. (1997) (75)
Fluid transport across the canine tracheal epithelium. (1980) (74)
CFTR gene transfer with AAV improves early cystic fibrosis pig phenotypes. (2016) (74)
Future directions in early cystic fibrosis lung disease research: an NHLBI workshop report. (2012) (74)
Human gene marker/therapy clinical protocols. (1996) (73)
The calcium signal and neutrophil activation. (1990) (73)
Localization and behaviors in null mice suggest that ASIC1 and ASIC2 modulate responses to aversive stimuli (2014) (72)
Neonates with cystic fibrosis have a reduced nasal liquid pH; a small pilot study. (2014) (71)
Effects of C-terminal deletions on cystic fibrosis transmembrane conductance regulator function in cystic fibrosis airway epithelia (2003) (70)
Lentiviral-mediated phenotypic correction of cystic fibrosis pigs. (2016) (70)
Cystic fibrosis gene therapy using an adenovirus vector: in vivo safety and efficacy in nasal epithelium. (1994) (70)
Endothelial barrier dysfunction caused by LPS correlates with phosphorylation of HSP27in vivo (2004) (70)
Simultaneous Disruption of Mouse ASIC1a, ASIC2 and ASIC3 Genes Enhances Cutaneous Mechanosensitivity (2012) (70)
Assessing mucociliary transport of single particles in vivo shows variable speed and preference for the ventral trachea in newborn pigs (2014) (68)
Altered expression of glomerular heat shock protein 27 in experimental nephrotic syndrome. (1996) (68)
Expression of cystic fibrosis transmembrane conductance regulator in a model epithelium. (1994) (67)
Expression of the 25-kDa heat-shock protein (HSP27) correlates with resistance to the toxicity of cadmium chloride, mercuric chloride, cis-platinum(II)-diammine dichloride, or sodium arsenite in mouse embryonic stem cells transfected with sense or antisense HSP27 cDNA. (1996) (67)
Ion transport by dog tracheal epithelium. (1980) (67)
PSD-95 and Lin-7b Interact with Acid-sensing Ion Channel-3 and Have Opposite Effects on H+-gated Current* (2004) (66)
Block by MOPS reveals a conformation change in the CFTR pore produced by ATP hydrolysis. (1997) (66)
Immunofluorescence colocalization of the 90-kDa heat-shock protein and microtubules in interphase and mitotic mammalian cells. (1989) (66)
Processing and function of CFTR-DeltaF508 are species-dependent. (2007) (65)
Oxidant regulated inter-subunit disulfide bond formation between ASIC1a subunits (2009) (63)
Sinus Hypoplasia Precedes Sinus Infection in a Porcine Model of Cystic Fibrosis (2012) (62)
Paradoxical Stimulation of a DEG/ENaC Channel by Amiloride* (1999) (61)
Pyrophosphate Stimulates Wild-type and Mutant Cystic Fibrosis Transmembrane Conductance Regulator Cl− Channels (*) (1995) (60)
Depletion of c-myc with specific antisense sequences reverses the transformed phenotype in ras oncogene-transformed NIH 3T3 cells (1991) (60)
Contribution of Proline Residues in the Membrane-spanning Domains of Cystic Fibrosis Transmembrane Conductance Regulator to Chloride Channel Function* (1996) (60)
Glycaemic regulation and insulin secretion are abnormal in cystic fibrosis pigs despite sparing of islet cell mass. (2015) (59)
Small molecule ion channels increase host defenses in cystic fibrosis airway epithelia (2019) (59)
Cell surface expression and biosynthesis of epithelial Na+ channels. (1998) (59)
Basolateral K+ channels in airway epithelia. II. Role in Cl- secretion and evidence for two types of K+ channel. (1990) (59)
Acute regulation of tight junction ion selectivity in human airway epithelia (2009) (58)
Concentration of the antibacterial precursor thiocyanate in cystic fibrosis airway secretions. (2011) (58)
p38 MAPK/HSP25 signaling mediates cadmium-induced contraction of mesangial cells and renal glomeruli. (2005) (58)
Relationships among CFTR expression, HCO3− secretion, and host defense may inform gene- and cell-based cystic fibrosis therapies (2016) (58)
Apical Localization of the Coxsackie-Adenovirus Receptor by Glycosyl-Phosphatidylinositol Modification Is Sufficient for Adenovirus-Mediated Gene Transfer through the Apical Surface of Human Airway Epithelia (2001) (57)
Propagation of infectious human papillomavirus type 16 by using an adenovirus and Cre/LoxP mechanism (2004) (57)
An Intrinsic Adenylate Kinase Activity Regulates Gating of the ABC Transporter CFTR (2003) (57)
Germ cell stimulation of Sertoli cell protein phosphorylation. (1987) (57)
CFTR with a partially deleted R domain corrects the cystic fibrosis chloride transport defect in human airway epithelia in vitro and in mouse nasal mucosa in vivo (2002) (57)
Sertoli cells from immature rats : in vitro stimulation of steroid metabolism by FSH. (1976) (55)
Expression of inositol 1,4,5-trisphosphate receptors changes the Ca2+ signal of Xenopus oocytes. (1996) (55)
Interaction of nucleotides with membrane-associated cystic fibrosis transmembrane conductance regulator. (1993) (55)
Covalent Modification of the Regulatory Domain Irreversibly Stimulates Cystic Fibrosis Transmembrane Conductance Regulator* (1997) (54)
Eukaryotic operon-like transcription of functionally related genes in Drosophila (2007) (53)
Induction of Hsp22 (HspB8) by estrogen and the metalloestrogen cadmium in estrogen receptor– positive breast cancer cells (2007) (53)
Myopathy-associated αB-crystallin Mutants (2007) (53)
Chloride secretion by canine tracheal epithelium: III. Membrane resistances and electromotive forces (2005) (53)
Cyclic AMP-dependent protein kinase activation of cystic fibrosis transmembrane conductance regulator chloride channels in planar lipid bilayers. (1992) (53)
Structural and functional similarities between the nucleotide-binding domains of CFTR and GTP-binding proteins. (1995) (53)
Human gene marker/therapy clinical protocols. (1999) (51)
Pancreatic damage in fetal and newborn cystic fibrosis pigs involves the activation of inflammatory and remodeling pathways. (2012) (50)
Effect of deletion mutations on the function of CFTR chloride channels. (1993) (50)
Sertoli cell capacity to metabolize C19 steroids: variation with age and the effect of follicle-stimulating hormone. (1978) (50)
TNF-α potentiates oxidant and reperfusion-induced endothelial cell injury (1996) (50)
Effect of inositol trisphosphate and calcium on oscillating elevations of intracellular calcium in Xenopus oocytes. (1990) (50)
Regulation of sodium absorption by canine tracheal epithelium. (1987) (50)
Assembly of the Epithelial Na+ Channel Evaluated Using Sucrose Gradient Sedimentation Analysis* (1998) (49)
Efficient killing of inhaled bacteria in ΔF508 mice: role of airway surface liquid composition. (1999) (49)
Cigarette smoke inhibition of ion transport in canine tracheal epithelium. (1983) (49)
Gene transfer for cystic fibrosis. (1999) (49)
Function of Xenopus Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Cl− Channels and Use of Human-Xenopus Chimeras to Investigate the Pore Properties of CFTR* (1996) (49)
Chloride secretion by canine tracheal epithelium: II. The cellular electrical potential profile (2005) (48)
Activation of MAP kinase and translocation with HSP27 in bombesin-induced contraction of rectosigmoid smooth muscle. (1995) (48)
Inhibition of the Cystic Fibrosis Transmembrane Conductance Regulator By ATP‐Sensitive K+ Channel Regulators a (1993) (47)
Basolateral K+ channels in airway epithelia. I. Regulation by Ca2+ and block by charybdotoxin. (1990) (47)
Evidence for basolateral membrane potassium conductance in canine tracheal epithelium. (1983) (47)
Effect of phorbol ester and calcium ionophore on chloride secretion in canine tracheal epithelium. (1987) (47)
Effect of subunit composition and Liddle's syndrome mutations on biosynthesis of ENaC. (1999) (47)
Localization of beta and gamma subunits of ENaC in sensory nerve endings in the rat foot pad. (2000) (46)
Variation in expression of hsp27 messenger ribonucleic acid during the cycle of the seminiferous epithelium and co-localization of hsp27 and microfilaments in Sertoli cells of the rat. (1996) (46)
Identification of a site of Hsp27 binding with Hsp27 and alpha B-crystallin as indicated by the yeast two-hybrid system. (1999) (45)
Calcium-dependent regulation of airway epithelial chloride channels. (1990) (45)
CFTR-deficient pigs display peripheral nervous system defects at birth (2013) (43)
Interactions of HSP22 (HSPB8) with HSP20, alphaB-crystallin, and HSPB3. (2005) (43)
Neuroleptics antagonize a calcium-activated potassium channel in airway smooth muscle (1987) (42)
Chloride secretion by canine tracheal epithelium: I. Role of intracellular cAMP levels (2005) (42)
Incorporation of Adeno-Associated Virus in a Calcium Phosphate Coprecipitate Improves Gene Transfer to Airway Epithelia In Vitro and In Vivo (2000) (42)
Nucleotide and deduced amino acid sequences of the matrix (M) and fusion (F) protein genes of cetacean morbilliviruses isolated from a porpoise and a dolphin. (1994) (42)
Fate of microfilaments in vero cells infected with measles virus and herpes simplex virus type 1 (1983) (41)
Sodium arsenite exposure alters cell migration, focal adhesion localization and decreases tyrosine phosphorylation of focal adhesion kinase in H9C2 myoblasts. (2005) (41)
Loss of Acid Sensing Ion Channel-1a and Bicarbonate Administration Attenuate the Severity of Traumatic Brain Injury (2013) (41)
The Cytoskeletal Protein α-Actinin Regulates Acid-sensing Ion Channel 1a through a C-terminal Interaction* (2009) (41)
Release of intracellular calcium by two different second messengers in airway epithelium. (1989) (41)
The evolution of morbilliviruses: a comparison of nucleocapsid gene sequences including a porpoise morbillivirus. (1995) (40)
Mucosal adenosine stimulates chloride secretion in canine tracheal epithelium. (1986) (40)
KGF alters gene expression in human airway epithelia: potential regulation of the inflammatory response. (2001) (40)
Bradykinin stimulates airway epithelial Cl- secretion via two second messenger pathways. (1990) (39)
Electrolyte transport properties in distal small airways from cystic fibrosis pigs with implications for host defense. (2016) (39)
Barium inhibition of basolateral membrane potassium conductance in tracheal epithelium. (1983) (39)
Activation of normal and cystic fibrosis Cl- channels by voltage, temperature, and trypsin. (1989) (39)
Acid-sensing ion channels interact with and inhibit BK K+ channels (2008) (38)
HORMONAL CONTROL OF CHLORIDE SECRETION BY CANINE TRACHEAL EPITHELIUM: AN ELECTROPHYSIOLOGIC ANALYSIS * (1981) (37)
Pancreatic and biliary secretion are both altered in cystic fibrosis pigs. (2012) (37)
Expression of CFTR and a cAMP-stimulated chloride secretory current in cultured human fetal alveolar epithelial cells. (1993) (37)
Abnormal interaction of motor neuropathy-associated mutant HspB8 (Hsp22) forms with the RNA helicase Ddx20 (gemin3) (2010) (36)
CFTR is required for maximal transepithelial liquid transport in pig alveolar epithelia. (2012) (36)
Adenovirus-Mediated Gene Transfer for Cystic Fibrosis: Part A. Safety of Dose and Repeat Administration in the Nasal Epithelium. Part B. Clinical Efficacy in the Maxillary Sinus. Howard Hughes Medical Institute, Iowa City, Iowa (1995) (36)
Hormonal Regulation of Sertoli Cells (1978) (35)
Dysfunction of CFTR bearing the delta F508 mutation. (1993) (35)
Shocking degeneration (2004) (34)
Mucus strands from submucosal glands initiate mucociliary transport of large particles. (2019) (34)
Inhibition of chloride secretion by furosemide in canine tracheal epithelium (2005) (34)
The effect of 2-methoxyethanol and methoxyacetic acid on Sertoli cell lactate production and protein synthesis in vitro. (1984) (34)
Neuronal necrosis is regulated by a conserved chromatin-modifying cascade (2014) (33)
Regulation of protein kinase inhibitor by follicle-stimulating hormone in Sertoli cells in vitro. (1981) (33)
cAMP and inositol 1,4,5-trisphosphate increase Ca2+ in HT-29 cells by activating different Ca2+ influx pathways. (1994) (33)
Processing of CFTR bearing the P574H mutation differs from wild-type and deltaF508-CFTR. (1999) (33)
Apical membrane Cl- channels in airway epithelia: anion selectivity and effect of an inhibitor. (1990) (33)
Ivacaftor-Induced Proteomic Changes Suggest Monocyte Defects May Contribute to the Pathogenesis of Cystic Fibrosis. (2016) (32)
Acute administration of ivacaftor to people with cystic fibrosis and a G551D-CFTR mutation reveals smooth muscle abnormalities. (2016) (32)
Cystic Fibrosis Transmembrane Conductance Regulator Cl− Channels with R Domain Deletions and Translocations Show Phosphorylation-dependent and -independent Activity* (2001) (32)
cAMP stimulation of HCO3- secretion across airway epithelia. (2001) (32)
Newborn Cystic Fibrosis Pigs Have a Blunted Early Response to an Inflammatory Stimulus. (2016) (31)
Protein inhibitor of cAMP-dependent protein kinase: Production and characterization of antibodies and intracellular localization (1980) (30)
Immunohistochemical Detection of Markers for Translational Studies of Lung Disease in Pigs and Humans (2016) (30)
Anion selectivity of the chloride-transport process in dog tracheal epithelium. (1980) (30)
Dysfunction of CFTR bearing the ΔF508 mutation (1993) (30)
Research on cystic fibrosis: a journey from the Heart House. (1998) (29)
Covalent Modification of the Nucleotide Binding Domains of Cystic Fibrosis Transmembrane Conductance Regulator* (1998) (29)
Myopathy-associated alphaB-crystallin mutants: abnormal phosphorylation, intracellular location, and interactions with other small heat shock proteins. (2007) (29)
Acid-sensing ion channel 3 (ASIC3) cell surface expression is modulated by PSD-95 within lipid rafts. (2008) (29)
Celebixanthone : A combined chemical and crystallographic structure proof (1963) (29)
The Drosophila Gene CheB42a Is a Novel Modifier of Deg/ENaC Channel Function (2010) (29)
Rapid Coomassie blue staining and destaining of polyacrylamide gels. (1996) (28)
Genetic factors of importance for β‐cell proliferation (1993) (28)
Large-scale gene discovery in human airway epithelia reveals novel transcripts. (2004) (28)
Variability of functional characteristics of MDCK cells. (1986) (26)
Spectrin and calmodulin in spreading mouse blastomeres. (1988) (26)
Lack of cystic fibrosis transmembrane conductance regulator disrupts fetal airway development in pigs (2018) (26)
Organic Functional Group Playing Card Deck (2003) (26)
An Activated Immune and Inflammatory Response Targets the Pancreas of Newborn Pigs with Cystic Fibrosis (2011) (26)
Motile cilia of human airway epithelia contain hedgehog signaling components that mediate noncanonical hedgehog signaling (2018) (26)
Polarized distribution of bradykinin receptors on airway epithelial cells and independent coupling to second messenger pathways. (1991) (26)
Mutations That Change the Position of the Putative γ-Phosphate Linker in the Nucleotide Binding Domains of CFTR Alter Channel Gating* (2002) (26)
Single apical membrane anion channels in primary cultures of canine tracheal epithelium (2004) (25)
Expressing acid-sensing ion channel 3 in the brain alters acid-evoked currents and impairs fear conditioning (2011) (25)
Calmodulin stabilization of kinetochore microtubule structure to the effect of nocodazole (1988) (25)
Pathways of ion movement in the canine tracheal epithelium. (1980) (25)
Human–mouse cystic fibrosis transmembrane conductance regulator (CFTR) chimeras identify regions that partially rescue CFTR-ΔF508 processing and alter its gating defect (2011) (25)
Vaccinia Virus Entry, Exit, and Interaction with Differentiated Human Airway Epithelia (2007) (25)
Effect of cAMP on intracellular and extracellular ATP content of Cl- -secreting epithelia and 3T3 fibroblasts. (1994) (25)
Acid-Sensing Ion Channels (ASICs) and pH in Synapse Physiology (2008) (25)
Alterations in calmodulin content and localization in areas of rat brain after repeated intermittent amphetamine (1991) (25)
ADP inhibits function of the ABC transporter cystic fibrosis transmembrane conductance regulator via its adenylate kinase activity. (2005) (24)
5'-Adenylylimidodiphosphate does not activate CFTR chloride channels in cell-free patches of membrane. (1993) (23)
Acid-Sensing Ion Channel 1a Contributes to Airway Hyperreactivity in Mice (2016) (23)
Repurposing tromethamine as inhaled therapy to treat CF airway disease. (2016) (23)
Chronic amphetamine treatment increases striatal calmodulin in rats (1986) (23)
TNF-alpha potentiates oxidant and reperfusion-induced endothelial cell injury. (1996) (23)
Intracellular chloride activities in the isolated perfused shark rectal gland. (1983) (23)
Developing fetal alveolar epithelial cells secrete fluid in primary culture. (1991) (23)
Conformational changes resulting from pseudophosphorylation of mammalian small heat shock proteins—a two-hybrid study (2006) (22)
Efficient killing of inhaled bacteria in DeltaF508 mice: role of airway surface liquid composition. (1999) (22)
Energetics of chloride secretion in canine tracheal epithelium. Comparison of the metabolic cost of chloride transport with the metabolic cost of sodium transport. (1984) (22)
Stimulation of rat Sertoli cell adenylate cyclase by germ cells in vitro. (1985) (22)
Association of Glycolysis-Enhancing α-1 Blockers With Risk of Developing Parkinson Disease (2021) (22)
Adenovirus-mediated gene transfer for cystic fibrosis: Part A. Safety of dose and repeat administration in the nasal epithelium. Part B. Clinical efficacy in the maxillary sinus. (1995) (22)
Adenylate Kinase Activity in ABC Transporters* (2005) (22)
Staphylococcus aureus alpha-toxin permeabilizes the basolateral membrane of a Cl(-)-secreting epithelium. (1992) (21)
Second messenger specificity of the inositol trisphosphate receptor: reappraisal based on novel inositol phosphates. (1994) (21)
Mechanisms of airway epithelial ion transport. (1986) (20)
InsP3 and Ins(1,3,4,5)P4 act in synergy to stimulate influx of extracellular Ca2+ in Xenopus oocytes. (1992) (20)
Dynamics of a fluorescent calmodulin analog in the mammalian mitotic spindle at metaphase. (1988) (20)
The low molecular weight heat shock protein (hsp27) in rat Sertoli cells: evidence for identity of hsp27 with a germ cell-responsive phosphoprotein. (1992) (20)
Transient acidosis while retrieving a fear-related memory enhances its lability (2017) (20)
Enamel Pathology Resulting from Loss of Function in the Cystic Fibrosis Transmembrane Conductance Regulator in a Porcine Animal Model (2011) (20)
Cystic fibrosis. (1995) (20)
Intracellular potassium activities in canine tracheal epithelium. (1983) (19)
Binding of the proline-rich region of the epithelial Na+ channel to SH3 domains and its association with specific cellular proteins. (1995) (19)
The second messenger pathway for germ cell-mediated stimulation of Sertoli cells. (1992) (18)
Ivacaftor-induced sweat chloride reductions correlate with increases in airway surface liquid pH in cystic fibrosis. (2018) (18)
The path of discovery in understanding the biology of cystic fibrosis and approaches to therapy. (1994) (18)
Localization of the viral and cellular Src kinases to perinuclear vesicles in fibroblasts. (1992) (18)
Targeting the basic defect in cystic fibrosis. (2010) (18)
Partial purification of the cystic fibrosis transmembrane conductance regulator. (1992) (18)
Localization of calmodulin and calmodulin acceptor sites by fluorescence methods. (1983) (17)
Combining Ivacaftor and Intensive Antibiotics Achieves Limited Clearance of Cystic Fibrosis Infections (2021) (17)
Phosphate stimulates CFTR Cl- channels. (1994) (17)
erbB1 Functions as a Sensor of Airway Epithelial Integrity by Regulation of Protein Phosphatase 2A Activity* (2006) (17)
AJRCCM: 100-Year Anniversary. Progress along the Pathway of Discovery Leading to Treatment and Cure of Cystic Fibrosis. (2017) (17)
Lack of airway submucosal glands impairs respiratory host defenses (2020) (17)
A study of vehicles for dosing rodent whole embryo culture with non aqueous soluble compounds. (2004) (16)
Basolateral chloride current in human airway epithelia. (2007) (16)
Inflammatory cytokines TNFα and IL-17 enhance the efficacy of cystic fibrosis transmembrane conductance regulator modulators. (2021) (16)
A conditional probability analysis of cystic fibrosis transmembrane conductance regulator gating indicates that ATP has multiple effects during the gating cycle (2001) (16)
Primary rat sertoli and interstitial cells exhibit a differential response to cadmium (2004) (16)
Two-dimensional gel analysis of Sertoli cell protein phosphorylation: effect of short term exposure to follicle-stimulating hormone. (1986) (16)
Calmodulin colocalization with cold-stable and nocodazole-stable microtubules in living PtK1 cells. (1988) (15)
Effect of lead acetate on Sertoli cell lactate production and protein synthesis in vitro (1986) (15)
Cell interactions in the rat seminiferous epithelium with special reference to the cellular distribution of calmodulin. (1986) (15)
Ion transport by primary cultures of canine tracheal epithelium: Methodology, morphology, and electrophysiology (2005) (15)
Cystic fibrosis transmembrane conductance regulator with a shortened R domain rescues the intestinal phenotype of CFTR−/− mice (2011) (15)
A method for purification of DNA species by high-speed centrifugation of agarose gel slices. (1995) (15)
Tetraethylammonium block of the BNC1 channel. (1999) (15)
Cystic fibrosis problem probed by proteolysis (1998) (14)
TNFα and IL-17 alkalinize airway surface liquid through CFTR and pendrin (2020) (14)
Anthracene-9-carboxylic acid inhibits an apical membrane, chloride conductance in canine tracheal epithelium (2005) (14)
Acidic Submucosal Gland pH and Elevated Protein Concentration Produce Abnormal Cystic Fibrosis Mucus. (2020) (14)
Electrophysiology of chloride-secreting epithelia. (1981) (14)
Fluoride stimulates cystic fibrosis transmembrane conductance regulator Cl- channel activity. (1998) (13)
PP2C gamma: a human protein phosphatase with a unique acidic domain. (1997) (13)
Protein phosphatase 2 C dephosphorylates and inactivates cystic fibrosis transmembrane conductance regulator (1997) (13)
A genomic signature approach to rescue ΔF508-cystic fibrosis transmembrane conductance regulator biosynthesis and function. (2014) (13)
Expression and Activity of Acid-Sensing Ion Channels in the Mouse Anterior Pituitary (2014) (12)
Repeat administration of an adenovirus vector encoding cftr to the nasal epithelium of patients with cystic fibrosis (1996) (12)
Differences between Cystic Fibrosis Transmembrane Conductance Regulator and HisP in the Interaction with the Adenine Ring of ATP* (2000) (12)
A COMPARATIVE STUDY OF SOME PYRIDINIUM OXIMES AS REACTIVATORS OF PHOSPHORYLATED ACETYLCHOLINESTERASE AND AS ANTIDOTES IN SARIN POISONING. (1963) (12)
Calmodulin is associated with microtubules forming in PTK1 cells upon release from nocodazole treatment. (1989) (11)
Inositol phosphate structural requisites for Ca2+ influx. (1995) (11)
HSP 27 in signal transduction and association with contractile proteins in smooth muscle cells (1999) (11)
Cystic fibrosis, CFTR, and abnormal electrolyte transport (1993) (10)
Effects of age, photoperiod and follicle-stimulating hormone on lactate production by cultured Sertoli cells from prepubertal Siberian hamsters (Phodopus sungorus). (1992) (9)
Role of CFTR’s intrinsic adenylate kinase activity in gating of the Cl− channel (2007) (9)
Human gene marker/therapy clinical protocols. (1997) (9)
Origins of cystic fibrosis lung disease. (2015) (9)
Cystic fibrosis. (1987) (9)
REGULATION OF SPINDLE MICROTUBULE ASSEMBLY-DISASSEMBLY: LOCALIZATION AND POSSIBLE FUNCTIONAL ROLE OF CALCIUM DEPENDENT REGULATOR PROTEIN (1978) (9)
Antisense Approaches to the Function of Glial Cell Proteins a (1992) (9)
Phosphorylation‐Dependent Regulation of Apical Membrane Chloride Channels in Normal and Cystic Fibrosis Airway Epithelium a (1989) (8)
Genetic factors of importance for beta-cell proliferation. (1993) (8)
Isoproterenol, cAMP, and bradykinin stimulate diacylglycerol production in airway epithelium. (1990) (8)
The vagal ganglia transcriptome identifies candidate therapeutics for airway hyperreactivity (2018) (8)
Nominal carbonic anhydrase activity minimizes airway‐surface liquid pH changes during breathing (2018) (8)
Neuron , Volume 64 Supplemental Data The Ion Channel ASIC 2 Is Required for Baroreceptor and Autonomic Control of the Circulation (2009) (8)
Evidence for a molecular mechanism of teratogenicity of SB-236057, a 5-HT1B receptor inverse agonist that alters axial formation. (2004) (7)
Mutating the Conserved Q-loop Glutamine 1291 Selectively Disrupts Adenylate Kinase-dependent Channel Gating of the ATP-binding Cassette (ABC) Adenylate Kinase Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and Reduces Channel Function in Primary Human Airway Epithelia* (2015) (7)
Characteristics of a cetacean morbillivirus isolated from a porpoise (Phocoena phocoena) (2005) (7)
A Mouse Model for the AF 508 Allele of Cystic Fibrosis (2013) (7)
Basolateral membrane potassium conductance is independent of sodium pump activity and membrane voltage in canine tracheal epithelium (2005) (7)
ThemammaliansodiumchannelBNC 1 is required for normal touch sensation (2000) (7)
Demonstration of Phosphoryl Group Transfer Indicates That the ATP-binding Cassette (ABC) Transporter Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Exhibits Adenylate Kinase Activity* (2012) (7)
Processing of CFTR bearing the P 574 H mutation differs from wild-type and ∆ F 508-CFTR (7)
Paracellular bicarbonate flux across human cystic fibrosis airway epithelia tempers changes in airway surface liquid pH (2020) (7)
Regulation of the cystic fibrosis transmembrane conductance regulator chloride channel by MgATP. (1993) (6)
The structure of celebixanthone (1962) (6)
Adrenergic regulation of ion transport by primary cultures of canine tracheal epithelium: Cellular electrophysiology (2005) (6)
Adrenergic stimulation of inositol phosphate accumulation in tracheal epithelium. (1989) (6)
Ion channels lose the rhythm (1995) (6)
Presence of matrix-specific antibodies in affinity-purified polyclonal antibodies. (1991) (6)
Cellular and molecular architecture of submucosal glands in wild-type and cystic fibrosis pigs (2022) (6)
Cystic fibrosis. Acidification indication. (1991) (5)
Chapter 7 The CFTR Chloride Channel (1994) (5)
A mutation in CFTR modifies the effects of the adenylate kinase inhibitor Ap5A on channel gating. (2008) (5)
Chapter 14 – Localization of Calmodulin in Tissue Culture Cells (1982) (5)
Amphotericin B induces epithelial voltage responses in people with cystic fibrosis. (2020) (5)
Mechanisms of airway epithelial ion transport. (1986) (5)
Membrane Resistances and Electromotive Forces during Stimulation of Chloride Secretion in the Canine Tracheal Epithelium (1982) (5)
Chemistry of Art and Color Sudoku Puzzles (2007) (5)
Beta-adrenergic-mediated Cl secretion: evidence for additional non-cAMP-dependent pathway of effect. (1990) (5)
Myopathy-associated B-crystallin Mutants ABNORMALPHOSPHORYLATION,INTRACELLULARLOCATION,ANDINTERACTIONS WITHOTHERSMALLHEATSHOCKPROTEINS * (2007) (5)
ATP and AMP Mutually Influence Their Interaction with the ATP-binding Cassette (ABC) Adenylate Kinase Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) at Separate Binding Sites* (2013) (5)
Short Communication Antibacterial properties of the CFTR potentiator ivacaftor (2014) (5)
FSH stimulation of protein kinase inhibitor: regulation of cellular metabolism. (1980) (5)
Cultured human endothelial cells and atherosclerosis. (1977) (4)
Cystic Fibrosis The genetic defects underlying this lethal disease have now been shown to eliminate or hobble a critical channel through which a constituent of salt enters and leaves cells (1995) (4)
Acidification indication (1991) (4)
Electrophysiological properties of human neutrophils. (1991) (4)
Identification and Characterization of hic-5 / ARA 55 as an hsp 27 Binding Protein * (2001) (4)
dT diaphorase: increased enzyme activity and mRNA expression in oxidant stress of skin. (1994) (4)
Cationic lipid mediated gene transfer of CFTR: safety of a single administration to the nasal epithelia. (1999) (4)
190 Mechanism for Sudden Unexpected Death in Epilepsy: The Amygdala as a Pathway to Seizure-Induced Apnea, Respiratory Agnosia and Sudden Death (2014) (4)
Speculations on the Role of the 90 kDa Heat Shock Protein in Glucocorticoid Receptor Transport and Function (1989) (4)
Elastic mucus strands impair mucociliary clearance in cystic fibrosis pigs (2022) (4)
Safety assessment of nebulized xylitol in beagle dogs (2012) (4)
AMP-PNP does not activate CFTR chloride channels in cell-free patches of membrane (1993) (3)
Abnormalities in baroreflex sensitivity and autonomic control in conscious ASIC2‐/‐ mice (2006) (3)
The Mechanism of Active Chloride Secretion by Airway Epithelia (1982) (3)
Pulmonary innate immunity and cystic fibrosis (2009) (3)
Adenovirus Calcium Phosphate Coprecipitates Enhance Squamous Cell Carcinoma Gene Transfer (2001) (3)
Interaction of the glucocorticoid receptor with the M(r) 90,000 heat shock protein (1989) (3)
The development of gene transfer for cystic fibrosis. (1995) (3)
WNK Inhibition Increases Surface Liquid pH and Host Defense in Cystic Fibrosis Airway Epithelia (2022) (2)
Fluoride stimulates cystic fibrosis transmembrane conductance regulator Cl- channel activity. (1998) (2)
Block by MOPS reveals a conformation change in the CFTR pore produced by ATP hydrolysis. (1997) (2)
Subcloning Of Genes Or Dna Fragments (2003) (2)
271* Pancreatic and biliary secretion differ in cystic fibrosis and wild-type pigs (2011) (2)
HSP27 expression regulates CCK-induced changes of the actin cytoskeleton in CHO-CCK-A cells. (1999) (2)
Regulation of the cystic fibrosis transmembrane conductance regulator Cl- channel by negative charge in the R domain. (1994) (2)
The development of gene transfer for cystic fibrosis. (1995) (2)
EFFECT OF HALOTHANE ON THE CELLULAR CYTOSKELETAL SYSTEM (1982) (2)
NaCl Transport in Tracheal Epithelium (1988) (2)
Pancreatic and Biliary Secretion Differ in Cystic Fibrosis and Wild-Type Pigs (2011) (2)
Role of Airway Epithelial Ion Transport in Pulmonary Mucociliary Clearance (1984) (2)
Postnatal airway growth in cystic fibrosis piglets. (2017) (2)
Early SFAS 106 adopters provide revealing healthcare data. (1993) (1)
Vaccinia Virus Entry, Exit, and Interaction with Differentiated Human Airway Epithelia (2007) (1)
Large-scale Expression And Purification Of Recombinant Proteins In Cultured Cells (2003) (1)
Abnormalities of airway epithelial chloride transport in cystic fibrosis (1994) (1)
New Strategies For Gene Knockout (2003) (1)
Small heat shock protein speciation: novel non-canonical 44 kDa HspB5-related protein species in rat and human tissues (2018) (1)
The ASIC1a antagonist PcTX‐1 reduces fear‐related behavior (2006) (1)
Gene Biotechnology, Second Edition (2003) (1)
Evidence that Ca2(+)-dependent activation of airway epithelia Cl- channels is not dependent on phosphorylation. (1990) (1)
Acid sensing ion channel 1 contributes to axonal degeneration in autoimmune CNS inflammation and provides a novel target for neuroprotection in multiple sclerosis (2008) (1)
WS02.4 Short-term and long-term effects of ivacaftor treatment on sputum microbiota in people with the G551D CFTR mutation (2015) (1)
The Pathway of Discovery in Pursuit of a Genetic Disease (1994) (1)
Bioinformation Superhighway and Computer Databases of Nucleic Acids and Proteins (2003) (1)
Molecular cardiology. Ion channels lose the rhythm. (1995) (1)
Author response: Transient acidosis while retrieving a fear-related memory enhances its lability (2017) (1)
Computational identification of operon-like transcriptional loci in eukaryotes (2013) (1)
Cystic fibrosis. Acidification indication. (1991) (0)
ASIC ion channels contribute to colonic mechanosensory function in mice (2003) (0)
Preparation of sterno from blackboard chalk: A "safe" student-teacher activity (1990) (0)
Title Intestinal CFTR expression alleviates meconium ileus in cysticfibrosis pigs (2013) (0)
Abstract 817: ASIC2 Expression Is an Important Determinant of Mechanotransduction in Nodose Neurons (2007) (0)
Construction and Screening of Subtracted and Complete Expression cDNA Libraries (2016) (0)
Down-Regulation of Gene Expression in Mammalian Systems via Current siRNA Technology (2003) (0)
VERSION ASIC 3 and ASIC 1 Mediate FMRFamide-Related Peptide Enhancement of H +-Gated Currents in Cultured Dorsal Root Ganglion Neurons (2003) (0)
High-Throughput Analysis of Gene Expression by Cutting- Edge Technology — DNA Microarrays (Gene Chips) (2003) (0)
Heteromultimers of DEG/ENa H+-gated channels in mouse (2016) (0)
Quantitative Analysis of Functional Genome by Real-Time RT-PCR (2016) (0)
Complexes adenovirus - molecules cationiques (1997) (0)
Human gene marker/therapy clinical protocols. (1996) (0)
Correction (1992) (0)
Analysis of Cellular DNA or Abundance of mRNA by Radioactivity in Situ Hybridization (RISH) (2003) (0)
Application of Correlative Microscopy to Genetic Therapy Research of Cystic Fibrosis and Other Human Diseases (2001) (0)
PARTICULATE MATERIAL STORAGE STRUCTURE BACKGROUND OF THE INVENTION (2017) (0)
Efficiently than Those from Group C Central Nervous System Cells More Group D Adenoviruses Infect Primary (2013) (0)
Acid‐sensing ion channel‐1a (ASIC1a) contributes to fear and associated autonomic/cardiovascular responses (2008) (0)
Corrections and Clarifications (1992) (0)
Rapid Isolation Of Specific cDNAs Or Genes by PCR (2003) (0)
HSP27 in signal transduction and association with contractile proteins in smooth muscle cells. (1999) (0)
Elevated Intracellular Calcium Transiently Increases Tight Junction Na+ Conductance in Human Airway Epithelia (2008) (0)
contractile proteins in smooth muscle cells HSP27 in signal transduction and association with (2016) (0)
Analysis Of Gene Expression At The Proteomic Level (2003) (0)
Altered esophageal mechanosensory function and pharmacology in mice lacking the ASIC ion channel (2003) (0)
CAREER SYMPOSIA : WHAT THE PROCESS TEACHES (1991) (0)
Localization of DNA or Abundance of mRNA by in situ Fluorescence Hybridization (FISH) (2003) (0)
Pickpocket is a novel DEG/ENaC protein expressed in drosophila mechanosensory neurons (1998) (0)
Transepithelial Electrolyte And Fluid Transport In Type II Alveolar Epithelia In A Porcine Model Of Cystic Fibrosis (2010) (0)
Introduction of François M. Abboud. (2010) (0)
Characterization of DNA or Genes by Southern Blot Hybridization (2003) (0)
Study of the effects of saturated fatty acids on the porcine epitheloid ileum IPI-2I cell line (2014) (0)
Corrections and Clarifications (1992) (0)
Correction (1992) (0)
The Capacity Of Rat Sertoli Cells In Vitro To Metabolize C19 Steroids And The Age Related Variation And Fsh Effect On Steroidogenic Enzyme Activities (1977) (0)
Chapter-19 Emotional Factors in Infertility and its Treatment (2012) (0)
Can type I diabetes mellitus be cured by enhanced b-cell replication induced by gene therapy? (1995) (0)
Culture Of Mouse Embryonic Stem Cells As A Model Mammalian Cell Line For Gene Expression (2003) (0)
New blood: Creative funding of disease-specific research (2015) (0)
Gene Overexpression by Sense RNA in Mammalian Systems (2016) (0)
Chair's Introduction (2008) (0)
Nominal Carbonic Anhydrase Activity Mitigates Airway‐Surface Liquid pH Changes During the Respiratory Cycle (2017) (0)
Nonisotopic and Isotopic DNA or RNA Sequencing (2003) (0)
Strategies For Novel Research Projects (2003) (0)
Human gene marker/therapy clinical protocols. (2000) (0)
Compositions comprising cationic amphiphilic lipids and co-facilitating administration via intracellular therapeutic molecules. (1997) (0)
531 Focal adhesion and cytoskeleton disruption by sodium arsenite reduces cell migration rates in muscle myoblasts (2003) (0)
In Reply: Chloride Channels in Cystic Fibrosis Patients (1990) (0)
Chapter 2 Membrane Topology, Subunit Composition, and Stoichiometry of the Epithelial Na+Channel (1999) (0)
SPECIES DEPENDENT SEVERITY OF CYSTIC FIBROSIS PHENOTYPE: RELATIONSHIP TO CALCIUM INDUCED ANION SECRETION? (2010) (0)
Function and Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator (1992) (0)
DrosophilaEukaryotic operon-like transcription of functionally related genes in Welsh (2006) (0)
Topography-dependent gene expression and function of common cell archetypes in large and small porcine airways (2021) (0)
Inositol phosphate production by cultured canine tracheal epithelium (1987) (0)
human airway epithelial permeability Histamine alters E-cadherin cell adhesion to increase (2015) (0)
110. Helper-Dependent Adenovirus with the Cytokeratin-18 Promoter Produces Greater Transepithelial Chloride Current and More Persistent Transgene Expression Than the CMV Promoter in Differentiated Human Airway Epithelia (2004) (0)
Research on cystic fibrosis: step 3? (1985) (0)
Response Chloride Channels in Cystic Fibrosis Patients (1990) (0)
Poster 9: A New Method to Quantitate Tumor Volume in a Mouse Model of Head and Neck Squamous Cell Carcinoma Involving Secreted Human Growth Hormone by a Transduced Cell Line (1996) (0)
Contents page,Editorial Board (2006) (0)
FateofMicrofilaments inVeroCells Infected withMeasles Virus andHerpesSimplex Virus Type1 (1983) (0)
ASIC1 expression contributes to demyelination and axonal injury in EAE and MS (2009) (0)
Isolation And Characterization Of Genes From Genomic Dna Libraries (2003) (0)
Author response: Lack of airway submucosal glands impairs respiratory host defenses (2020) (0)
Protective effects by overexpression of Hsp27 against caerulein-induced acute pancreatitis (2003) (0)
Identification of candidate protein biomarkers for BPI3V diagnosis using an in vitro infection model (2016) (0)
Stone babies still occur. (1989) (0)
Overexpression of human HSP27 enhances amylase secretion and stabilizes the actin cytoskeleton in isolated pancreatic acini (2000) (0)
Analysis of Gene Expression at the Functional Genomic Level (2003) (0)
Insights into the pathogenesis of cystic fibrosis (1997) (0)
Emergency medicine and family physicians. (1997) (0)
In Situ PCR Hybridization of Low Copy Genes and in situ RT-PCR Detection of Low Abundance mRNAs (2003) (0)
High Pressure NMR Studies of Supercooled Viscous Fluids (1987) (0)
Compositions with cationic amphiphilic and colipids for intracellular delivery of therapeutic molecules (1997) (0)
7. Lentiviral Vector-Mediated CFTR Gene Transfer to CF Pig Airways Corrects the Anion Transport Defect In Vivo (2015) (0)
Quantitative Analysis Of Functional Genome By Current Real-time RT-PCR (2003) (0)
Human gene marker/therapy clinical protocols. (1999) (0)
SERTOLI CELL BY FOLLICLE STIMULATING HORMONE (1980) (0)
Erratum: Vaccinia virus entry, exit, and interaction with differentiated human airway epithelia (Journal of Virology (2007) 81, 18, (9891-9899)) (2007) (0)
SPECIES DEPENDENT SEVERITY OF CYSTIC FIBROSIS PHENOTYPE (2010) (0)
potential regulation of the inflammatory response KGF alters gene expression in human airway epithelia (2015) (0)
CALPROTECTIN EXPRESSION IS CONSTITUTIVELY ALTERED IN THE CF PIG AT BIRTH PRIOR TO THE ONSET OF NEUTROPHIL-MEDIATED INFLAMMATION (2015) (0)
Construction and Screening of Human Antibody Libraries: Using State-of-the-Art Technology — Phage Display (2003) (0)
Gene Underexpression in Cultured Cells and Animals by Antisense DNA and RNA Strategies (2003) (0)

This paper list is powered by the following services:

Other Resources About Michael J. Welsh

en.wikipedia.org

What Schools Are Affiliated With Michael J. Welsh ?

Michael J. Welsh is affiliated with the following schools:

Michael J. Welsh 's Academic­Influence.com Rankings