Michael Jeltsch

Q: What Schools Are Affiliated With Michael Jeltsch

Michael Jeltsch is affiliated with the following schools: University of California, Berkeley, Stanford University, University of Helsinki

Michael Jeltsch's AcademicInfluence.com Rankings

Michael Jeltsch

Biology

#12791

World Rank

#16290

Historical Rank

Biochemistry

#2635

World Rank

#2811

Historical Rank

biology Degrees

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Biology

Michael Jeltsch's Degrees

PhD Biochemistry University of California, Berkeley
Masters Chemistry Stanford University
Bachelors Chemistry Stanford University

Why Is Michael Jeltsch Influential?

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According to Wikipedia, Michael Jeltsch is a German-Finnish researcher in the field of Biochemistry. He is an associate professor at the University of Helsinki, Finland. He has more than 70 publications. Jeltsch was the first to show that VEGF-C and VEGF-D are the principal growth factors for the lymphatic vasculature and his research focuses on cancer drug targets and lymphangiogenesis. He has also contributed to other seminal publications in cell biology with transgenesis, protein engineering, recombinant production and purification. In 2006, he developed a synthetic super-VEGF, using a library of VEGF hybrid molecules using a novel, non-random DNA family shuffling method.

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Michael Jeltsch's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia (2003) (2714)
Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins (2004) (1346)
Hyperplasia of lymphatic vessels in VEGF-C transgenic mice. (1997) (1291)
Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4). (1998) (1185)
Vascular endothelial growth factor‐C‐mediated lymphangiogenesis promotes tumour metastasis (2001) (961)
Proteolytic processing regulates receptor specificity and activity of VEGF‐C (1997) (806)
VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development. (1996) (707)
Signalling via vascular endothelial growth factor receptor‐3 is sufficient for lymphangiogenesis in transgenic mice (2001) (665)
Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation. (2005) (595)
Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells. (1998) (562)
VEGF and VEGF-C: specific induction of angiogenesis and lymphangiogenesis in the differentiated avian chorioallantoic membrane. (1997) (498)
Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels. (2005) (394)
Functional interaction of VEGF‐C and VEGF‐D with neuropilin receptors (2006) (307)
Adenoviral Expression of Vascular Endothelial Growth Factor-C Induces Lymphangiogenesis in the Skin (2001) (228)
Genomic Organization of Human and Mouse Genes for Vascular Endothelial Growth Factor C* (1997) (219)
Vascular endothelial growth factor (VEGF)‐C synergizes with basic fibroblast growth factor and VEGF in the induction of angiogenesis in vitro and alters endothelial cell extracellular proteolytic activity (1998) (205)
CCBE1 Enhances Lymphangiogenesis via A Disintegrin and Metalloprotease With Thrombospondin Motifs-3–Mediated Vascular Endothelial Growth Factor-C Activation (2014) (188)
Current biology of VEGF-B and VEGF-C. (1999) (188)
Adenoviral VEGF‐C overexpression induces blood vessel enlargement, tortuosity, and leakiness but no sprouting angiogenesis in the skin or mucous membranes (2002) (180)
Structural determinants of growth factor binding and specificity by VEGF receptor 2 (2010) (178)
Vascular endothelial growth factor D ( VEGF-D ) is a ligand for the tyrosine kinases VEGF receptor 2 ( Flk 1 ) and VEGF receptor 3 ( Flt 4 ) (1998) (175)
Vascular endothelial growth factors VEGF‐B and VEGF‐C (1997) (147)
Intravascular Adenovirus-Mediated VEGF-C Gene Transfer Reduces Neointima Formation in Balloon-Denuded Rabbit Aorta (2000) (143)
Vascular Endothelial Growth Factor-B Acts as a Coronary Growth Factor in Transgenic Rats Without Inducing Angiogenesis, Vascular Leak, or Inflammation (2010) (141)
Overexpression of Vascular Endothelial Growth Factor-B in Mouse Heart Alters Cardiac Lipid Metabolism and Induces Myocardial Hypertrophy (2008) (141)
Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization. (2010) (140)
Receptor tyrosine kinase-mediated angiogenesis. (2013) (139)
Reevaluation of the Role of VEGF-B Suggests a Restricted Role in the Revascularization of the Ischemic Myocardium (2008) (112)
Activated Forms of VEGF-C and VEGF-D Provide Improved Vascular Function in Skeletal Muscle (2009) (110)
A truncation allele in vascular endothelial growth factor c reveals distinct modes of signaling during lymphatic and vascular development (2013) (107)
The tyrosine kinase inhibitor cediranib blocks ligand-induced vascular endothelial growth factor receptor-3 activity and lymphangiogenesis. (2008) (104)
Genesis and pathogenesis of lymphatic vessels (2003) (100)
CCBE1 Enhances Lymphangiogenesis via ADAMTS3-Mediated VEGF-C Activation (2014) (97)
Structural determinants of vascular endothelial growth factor-D receptor binding and specificity. (2011) (96)
Structural and mechanistic insights into VEGF receptor 3 ligand binding and activation (2013) (81)
Intrinsic versus microenvironmental regulation of lymphatic endothelial cell phenotype and function (2003) (78)
Efficient activation of the lymphangiogenic growth factor VEGF-C requires the C-terminal domain of VEGF-C and the N-terminal domain of CCBE1 (2017) (70)
Biology of Vascular Endothelial Growth Factor C in the Morphogenesis of Lymphatic Vessels (2018) (69)
The Basis for the Distinct Biological Activities of Vascular Endothelial Growth Factor Receptor–1 Ligands (2013) (54)
Suppressive Effects of Vascular Endothelial Growth Factor-B on Tumor Growth in a Mouse Model of Pancreatic Neuroendocrine Tumorigenesis (2010) (52)
Vascular Endothelial Growth Factor-Angiopoietin Chimera With Improved Properties for Therapeutic Angiogenesis (2013) (51)
Vascular Endothelial Growth Factor (VEGF)/VEGF-C Mosaic Molecules Reveal Specificity Determinants and Feature Novel Receptor Binding Patterns* (2006) (45)
Critical role of VEGF-C/VEGFR-3 signaling in innate and adaptive immune responses in experimental obliterative bronchiolitis. (2012) (44)
Key molecules in lymphatic development, function, and identification. (2018) (39)
Distinct Architecture of Lymphatic Vessels Induced by Chimeric Vascular Endothelial Growth Factor-C/Vascular Endothelial Growth Factor Heparin-Binding Domain Fusion Proteins (2007) (39)
Functional Dissection of the CCBE1 Protein: A Crucial Requirement for the Collagen Repeat Domain. (2015) (38)
Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development. (2010) (36)
Ischemia–Reperfusion Injury Enhances Lymphatic Endothelial VEGFR3 and Rejection in Cardiac Allografts (2016) (30)
KLK3/PSA and cathepsin D activate VEGF-C and VEGF-D (2019) (28)
Functional Importance of a Proteoglycan Coreceptor in Pathologic Lymphangiogenesis (2016) (27)
Lymphatic Vessels in Regenerative Medicine and Tissue Engineering. (2016) (27)
VEGF-C Protects the Integrity of Bone Marrow Perivascular Niche. (2020) (23)
Proteolytic Cleavages in the VEGF Family: Generating Diversity among Angiogenic VEGFs, Essential for the Activation of Lymphangiogenic VEGFs (2021) (17)
Factors regulating the substrate specificity of cytosolic phospholipase A2-alpha in vitro. (2016) (14)
Enhanced Capillary Formation Stimulated by a Chimeric Vascular Endothelial Growth Factor/Vascular Endothelial Growth Factor-C Silk Domain Fusion Protein (2007) (14)
Substrate Efflux Propensity Is the Key Determinant of Ca2+-independent Phospholipase A-β (iPLAβ)-mediated Glycerophospholipid Hydrolysis* (2015) (12)
The TIE Receptor Family (2015) (8)
Investigation on the role of biallelic variants in VEGF‐C found in a patient affected by Milroy‐like lymphedema (2020) (4)
KLK3 in the Regulation of Angiogenesis—Tumorigenic or Not? (2021) (4)
The Proteolytic Activation of Vascular Endothelial Growth Factors (2021) (3)
The lymphangiogenic growth factors VEGF-C and VEGF-D Part 1 : Fundamentals and embryonic development (2015) (2)
341 VEGF-C/VEGFR-3 Signaling Regulates Inflammatory Response in Development of Obliterative Airway Disease (2011) (1)
The lymphangiogenic growth factors VEGF-C and VEGF-D Part 2 : The role ofVEGF-C and VEGF-D in diseases involving the lymphatic system (2015) (1)
Bioactive VEGF-C from E. coli (2022) (1)
Inhibition of VEGF-C-induced VEGFR-3 activity and lymphatic endothelial cell function by the tyrosine kinase inhibitor AZD2171 (2007) (1)
Heterogeneity of the origin of the lymphatic system (2016) (1)
receptor 2 (Flk1) and VEGF receptor 3 (Flt4) Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF (2007) (1)
Outside in and brakes off for lymphatic growth (2021) (1)
Lymphatic-to-blood vessel transdifferentiation in zebrafish (2022) (1)
Expansion and collapse of VEGF diversity in major clades of the animal kingdom (2023) (0)
Vascular Endothelial Growth Factor (VEGF)/VEGF-C Mosaic Molecules Reveal Specificity Determinants and Feature Novel (2006) (0)
VEGF-C adenovirus gene transfer reduces intima formation in rabbits (2000) (0)
Crystal structure of VEGF-C in complex with VEGFR-3 domains D1-2 (2013) (0)
Lymphangiogenesis in Health and Disease (2015) (0)
Author response: KLK3/PSA and cathepsin D activate VEGF-C and VEGF-D (2019) (0)
From Molecular Genetics and Biology to Effective Treatments of Lymphatic Disorders (2016) (0)
Efficient activation of the lymphangiogenic growth factor VEGF-C requires the C-terminal domain of VEGF-C and the N-terminal domain of CCBE1 (2017) (0)
binding and specificity Structural determinants of vascular endothelial growth factor-D receptor (2011) (0)
VEGFR-3 Ligands and Lymphangiogenesis (2002) (0)
Crystal structure of vascular endothelial growth factor D (2011) (0)
Crystal Structure of VEGF-C in Complex with Domains 2 and 3 of VEGFR2 (2010) (0)
Crystal structure of VEGFR-3 extracellular domains D4-5 (2013) (0)
Lymphangiogenesis VEGFR-3 Ligands (2002) (0)
CRYSTAL STRUCTURE OF VEGF-C IN COMPLEX WITH DOMAINS 2 AND 3 OF VEGFR2 IN A TETRAGONAL CRYSTAL FORM (2010) (0)

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What Schools Are Affiliated With Michael Jeltsch?

Michael Jeltsch is affiliated with the following schools:

Michael Jeltsch's Academic­Influence.com Rankings