Michael L. Shelanski
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Biology
Michael L. Shelanski's Degrees
- Masters Biology Stanford University
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(Suggest an Edit or Addition)Michael L. Shelanski's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Microtubule assembly in the absence of added nucleotides. (1973) (1812)
- Common variants in MS4A4/MS4A6E, CD2uAP, CD33, and EPHA1 are associated with late-onset Alzheimer’s disease (2011) (1656)
- Primary age-related tauopathy (PART): a common pathology associated with human aging (2014) (988)
- Primary care outcomes in patients treated by nurse practitioners or physicians: a randomized trial. (2000) (958)
- Turbidimetric studies of the in vitro assembly and disassembly of porcine neurotubules. (1974) (695)
- Synergistic Effects of Traumatic Head Injury and Apolipoprotein-epsilon4 in Patients With Alzheimer's Disease (1995) (584)
- Astroglia in CNS injury (1991) (520)
- Amyloid β-peptide inhibition of the PKA/CREB pathway and long-term potentiation: Reversibility by drugs that enhance cAMP signaling (2002) (509)
- Persistent improvement in synaptic and cognitive functions in an Alzheimer mouse model after rolipram treatment. (2004) (421)
- Ubiquitin Hydrolase Uch-L1 Rescues β-Amyloid-Induced Decreases in Synaptic Function and Contextual Memory (2006) (386)
- EFFECTS OF MITOTIC SPINDLE INHIBITORS ON NEUROTUBULES AND NEUROFILAMENTS IN ANTERIOR HORN CELLS (1968) (368)
- Caspase-2 Mediates Neuronal Cell Death Induced by β-Amyloid (2000) (334)
- ISOLATION OF A PROTEIN SUBUNIT FROM MICROTUBULES (1967) (293)
- Common variants at MS 4 A 4 / MS 4 A 6 E , CD 2 AP , CD 33 and EPHA 1 are associated with late-onset Alzheimer ’ s disease (2011) (274)
- Cyclin-dependent Kinases Participate in Death of Neurons Evoked by DNA-damaging Agents (1998) (269)
- Role of Cell Cycle Regulatory Proteins in Cerebellar Granule Neuron Apoptosis (1999) (251)
- Synaptic changes in Alzheimer’s disease and its models (2013) (249)
- Isolation and characterization of amyloid P component from Alzheimer's disease and other types of cerebral amyloidosis. (1988) (247)
- Suppression by antisense mRNA demonstrates a requirement for the glial fibrillary acidic protein in the formation of stable astrocytic processes in response to neurons (1991) (241)
- β‐Amyloid‐induced neuronal apoptosis requires c‐Jun N‐terminal kinase activation (2001) (240)
- Dendrite and dendritic spine alterations in alzheimer models (2004) (240)
- Primary structure of high molecular weight tau present in the peripheral nervous system. (1992) (227)
- Highly Efficient Small Interfering RNA Delivery to Primary Mammalian Neurons Induces MicroRNA-Like Effects before mRNA Degradation (2004) (226)
- PROPERTIES OF THE PROTEIN SUBUNIT OF CENTRAL-PAIR AND OUTER-DOUBLET MICROTUBULES OF SEA URCHIN FLAGELLA (1968) (214)
- Reversal of long-term dendritic spine alterations in Alzheimer disease models (2009) (213)
- Interactions between neurofilaments and microtubule-associated proteins: a possible mechanism for intraorganellar bridging (1982) (213)
- Neurogenic Effect of β-Amyloid Peptide in the Development of Neural Stem Cells (2004) (202)
- Vinblastine-Induced Precipitation of Microtubule Protein (1969) (195)
- Regulation of a high molecular weight microtubule-associated protein in PC12 cells by nerve growth factor (1983) (181)
- Microinjection of Ca++-calmodulin causes a localized depolymerization of microtubules (1983) (176)
- Defects in Nuclear and Cytoskeletal Morphology and Mitochondrial Localization in Spermatozoa of Mice Lacking Nectin-2, a Component of Cell-Cell Adherens Junctions (2000) (174)
- Increased neurogenesis in young transgenic mice overexpressing human APP(Sw, Ind). (2007) (172)
- Two separate 18-amino acid domains of tau promote the polymerization of tubulin. (1989) (169)
- Biochemistry of the filaments of brain. (1976) (164)
- Caspase-2 mediates neuronal cell death induced by beta-amyloid. (2000) (164)
- Induction of CPP32-like Activity in PC12 Cells by Withdrawal of Trophic Support (1996) (164)
- Involvement of Retinoblastoma Family Members and E2F/DP Complexes in the Death of Neurons Evoked by DNA Damage (2000) (164)
- Nedd2 Is Required for Apoptosis after Trophic Factor Withdrawal, But Not Superoxide Dismutase (SOD1) Downregulation, in Sympathetic Neurons and PC12 Cells (1997) (159)
- Alzheimer's neurofibrillary tangles contain unique epitopes and epitopes in common with the heat-stable microtubule associated proteins tau and MAP2. (1987) (152)
- Local cytoplasmic calcium gradients in living mitotic cells (1985) (151)
- Astrocyte process growth induction by actin breakdown (1992) (151)
- Regulation of peripherin and neurofilament expression in regenerating rat motor neurons (1990) (151)
- Dysregulation of microRNA-219 promotes neurodegeneration through post-transcriptional regulation of tau. (2015) (146)
- Death in the Balance: Alternative Participation of the Caspase-2 and -9 Pathways in Neuronal Death Induced by Nerve Growth Factor Deprivation (2001) (146)
- A dynein‐like protein associated with neurotubules (1974) (140)
- Induction in vitro of Microtubular Crystals by Vinca Alkaloids (1969) (136)
- MICROTUBULE PROTEIN : Identification in and Transport to Nerve Endings (1971) (136)
- Cytosolic free calcium and cell spreading decrease in fibroblasts from aged and Alzheimer donors. (1986) (135)
- Isolation of Filaments from Brain (1971) (132)
- Neurofibrillary degeneration induced by vincristine therapy. (1969) (127)
- Protein changes in senile dementia. (1974) (115)
- Heterogeneity of tubulin subunits. (1971) (114)
- Biochemical and immunological characterization of neurofilaments in experimental neurofibrillary degeneration induced by aluminum (1979) (113)
- STRUCTURE OF MICROTUBULAR CRYSTALS INDUCED BY VINBLASTINE IN VITRO (1970) (111)
- On the association between microtubules and mitochondria within axons. (1971) (105)
- Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer’s disease-like pathologies and cognitive deficits (2017) (98)
- Neurogenic effect of beta-amyloid peptide in the development of neural stem cells. (2004) (98)
- β-Amyloid (Aβ) Oligomers Impair Brain-derived Neurotrophic Factor Retrograde Trafficking by Down-regulating Ubiquitin C-terminal Hydrolase, UCH-L1* (2013) (94)
- High molecular weight tau: preferential localization in the peripheral nervous system. (1991) (92)
- Transition from metaphase to anaphase is accompanied by local changes in cytoplasmic free calcium in Pt K2 kidney epithelial cells. (1986) (91)
- Microtubule-associated proteins bind specifically to the 70-kDa neurofilament protein. (1985) (91)
- Direct visualization of fluorescein-labeled microtubules in vitro and in microinjected fibroblasts (1981) (89)
- Expression of high molecular weight tau in the central and peripheral nervous systems. (1993) (84)
- Interactions of tubulin with vinblastine and guanosine triphosphate. (1972) (83)
- Cytoplasmic filaments and tubules. (1968) (81)
- Comparison of surface membranes isolated from cultured murine neuroblastoma cells in the differentiated or undifferentiated state. (1974) (80)
- A circular dichroism study of microtubule protein. (1972) (78)
- Assembly and Interrogation of Alzheimer’s Disease Genetic Networks Reveal Novel Regulators of Progression (2015) (77)
- Caspase-2 is required for dendritic spine and behavioral alterations in J20 APP transgenic mice (2013) (77)
- Altered response of fibroblasts from aged and Alzheimer donors to drugs that elevate cytosolic free calcium (1988) (74)
- Preferential phosphorylation of the 150,000 molecular weight component of neurofilaments by a cyclic AMP-dependent, microtubule-associated protein kinase (1981) (73)
- Long-lasting and rapid calcium changes during mitosis (1988) (72)
- Specific downregulation of hippocampal ATF4 reveals a necessary role in synaptic plasticity and memory. (2015) (71)
- Gene-Wise Association of Variants in Four Lysosomal Storage Disorder Genes in Neuropathologically Confirmed Lewy Body Disease (2015) (70)
- RTP801/REDD1 Regulates the Timing of Cortical Neurogenesis and Neuron Migration (2011) (62)
- Distribution of the Protease Inhibitor α1Antichymotrypsin in Cerebral and Systemic Amyloid (1990) (61)
- Is tubulin a glycoprotein? (1975) (55)
- Stabilization of dynamic microtubules by mDia1 drives Tau-dependent Aβ1–42 synaptotoxicity (2017) (51)
- CHEMISTRY OF THE FILAMENTS AND TUBULES OF BRAIN (1973) (50)
- Activating transcription factor 4 (ATF4) modulates post-synaptic development and dendritic spine morphology (2014) (44)
- Protection against β-amyloid induced abnormal synaptic function and cell death by Ginkgolide J (2009) (44)
- Microtubules and intermediate filaments. (1976) (43)
- Intracellular free calcium levels are reduced in mitotic Pt K2 epithelial cells. (1985) (40)
- β-Protein deposition: a pathogenetic link between Alzheimer's disease and cerebral amyloid angiopathies (1988) (40)
- Characterization of a PC12 cell sub-clone (PC12-C41) with enhanced neurite outgrowth capacity: implications for a modulatory role of high molecular weight tau in neuritogenesis. (1993) (40)
- Interaction of nerve growth factor with pheochromocytoma cells. Evidence for tight binding and sequestration (1980) (38)
- Cross-Linking of Cell Surface Amyloid Precursor Protein Leads to Increased β-Amyloid Peptide Production in Hippocampal Neurons: Implications for Alzheimer's Disease (2012) (35)
- 2 – Filaments and Tubules in the Nervous System (1972) (34)
- Resting [Ca2+]i and [Ca2+]i transients are similar in fibroblasts from normal and Alzheimer's donors (1992) (33)
- Glycoproteins released into the culture medium of differentiating murine neuroblastoma cells. (1975) (32)
- Observations on axoplasmic transport in rabbits with aluminum-induced neurofibrillary tangles. (1974) (32)
- Effects of neurotoxic industrial solvents on cultured neuroblastoma cells: methyl n-butyl ketone, n-hexane and derivatives. (1978) (32)
- Biochemical correlates of astrocytic proliferation in the mutant Staggerer mouse (1977) (32)
- tau Regulation of microtubule-microtubule spacing and bundling. (1994) (31)
- The carbohydrate composition of brain microtubule protein. (1972) (31)
- Peripherin: a novel marker for the immunohistochemical study of malformations of the enteric nervous system. (1996) (29)
- Dibutyryl cyclic AMP-induced process formation in astrocytes is associated with a decrease in tyrosine phosphorylation of focal adhesion kinase and paxillin. (1999) (29)
- Generation of iPSC lines from archived non-cryoprotected biobanked dura mater (2014) (28)
- Identity of the major protein in ‘native’ glial fibrillary acidic protein preparation with tubulin (1978) (27)
- Promotion of Microtubule Assembly by Neurofilament‐Associated Microtubule‐Associated Proteins (1984) (27)
- Anomalous function of vimentin in chronic lymphocytic leukemia lymphocytes. (1984) (25)
- Neuron-astroglial interactions in vitro and their implications for repair of CNS injury. (1984) (24)
- C17, a retrovirally immortalized neuronal cell line, inhibits the proliferation of astrocytes and astrocytoma cells by a contact‐mediated mechanism (1990) (22)
- Activating Transcription Factor 4 (ATF4) Regulates Neuronal Activity by Controlling GABABR Trafficking (2018) (20)
- Calcium and Calmodulin in the Regulation of the Microtubular Cytoskeleton a (1986) (20)
- Divergence of the apoptotic pathways induced by 4-hydroxynonenal and amyloid β-protein (2004) (19)
- Membrane linked proteins at CNS synapses (1977) (19)
- Chemistry and biology of neuronal and glial intermediate filaments. (1982) (19)
- EACH COMPONENT OF NEUROFILAMENT ASSEMBLES ITSELF TO MAKE COMPONENT-SPECIFIC FILAMENT (1984) (18)
- Protein differences associated with the absence of granule cells in the cerebella from the mutant weaver mouse and from X‐irradiated rat (1974) (17)
- Immunological and biochemical comparison of tubulin and intermediate brain filament protein (1977) (17)
- SYNTHESIS OF A COLCHICINE-BINDING PROTEIN DURING THE HELA CELL LIFE CYCLE (1969) (16)
- Intracellular Ionic Calcium and the Cytoskeleton in Living Cells (1989) (15)
- NEUROFILAMENTS (1979) (15)
- Evidence for interactions between neurofilaments and microtubules. (1981) (14)
- Methods for the Neurochemical Study of Microtubules (1974) (13)
- The multiple molecular forms of acetylcholinesterase in “motor end-plate disease” in the mouse (medJ and med allelic forms): Sensitivity of the 10 S form to partial or total loss of muscle activity (1983) (13)
- Brain-Derived Neurotrophic Factor Elevates Activating Transcription Factor 4 (ATF4) in Neurons and Promotes ATF4-Dependent Induction of Sesn2 (2018) (12)
- Some features of the vinblastine-induced assembly of porcine tubulin. (1975) (9)
- Activating Transcription Factor 4 (ATF4) modulates Rho GTPase levels and function via regulation of RhoGDIα (2016) (8)
- Rapid purification of intact tonofilaments from newborn rats. Comparison with glial filaments and neurofilaments. (1980) (8)
- Process Formation in Astrocytes: Modulation of Cytoskeletal Proteins (1998) (7)
- A Systems Approach to Drug Discovery in Alzheimer’s Disease (2015) (7)
- Structural Implications of a cDNA Clone Encoding Mouse Glial Fibrillary Acidic Protein (1985) (7)
- Some biochemical aspects of neurotubule and neurofilament proteins. (1972) (7)
- Mechanisms of the Promotion of Neurite Outgrowth by Nerve Growth Factor (1984) (7)
- Caspase-2 and tau—a toxic partnership? (2016) (7)
- Functional Role of RNA Polymerase II and P70 S6 Kinase in KCl Withdrawal-induced Cerebellar Granule Neuron Apoptosis* (2015) (7)
- Distribution of the protease inhibitor alpha 1-antichymotrypsin in cerebral and systemic amyloid. (1990) (6)
- Transition from metaphase to anaphase is accompanied by local changes in-cytoplasmic free calcium in Pt K 2 kidney epithelial cells ( fura-2 / digital image processing / mitosis / microtubules / ATP permeabilization ) (6)
- Regulation of a High Molecular Microtu bu le-associated Protein by Nerve Growth Factor Weight in PC12 Cells (1983) (6)
- Collagenase-induced alteration in mouse 16S acetylcholinesterase (1979) (6)
- IMMUNOHISTOLOGICAL LOCALIZATION OF THE NEUROFILAMENT PROTEIN IN THE HOUSE: 93 (1976) (5)
- The Cytoskeleton and Neuronal Disease (1981) (5)
- A circular dichroism study of microtubule protein. (1972) (4)
- MICROTUBULE PROTEIN (1971) (4)
- New insights on the composition of neurofilaments. (1979) (4)
- The formation of filamentous structures from iodinated neurotubules. (1975) (3)
- Neurofibrillary degeneration induced by Vinca alkaloids: clinical and experimental. (1968) (3)
- A Method for the Isolation of Mammalian Neurofilaments (1970) (2)
- Cytoskeletons of central and peripheral neurons (1994) (2)
- 48 NEUROFILAMENTS: PURIFICATION AND PHOSPHOPROTEIN KINASE ACTIVITY (1981) (2)
- Cytoskeleton and NGF in the pathogenesis and treatment of Alzheimer's disease (1989) (2)
- THE NEUROFILAMENT AND GLIAL FILAMENT ARE BIOCHEMICALLY DISTINCT (1978) (2)
- The Cytoskeleton in Neurological Disease (1990) (2)
- Rapid ATF4 Depletion Resets Synaptic Responsiveness after cLTP (2021) (2)
- The use of microinjection and video microscopy for the study of calmodulin and calcium in living cells. (1987) (2)
- Neurofibrillary Degeneration: The Role of Aluminum (1986) (1)
- Antisense Methods for Probing Intermediate Filament Function (1993) (1)
- The Fibrous Proteins of Brain: A Primer for Gerontologists (1977) (1)
- Calcium and the Cytoskeleton in Alzheimer’s Disease (1989) (1)
- Stuck in the Mire (2015) (1)
- Anomalous Function of Vimentin in Chronic Lymphocytic (2005) (1)
- Apolipoprotein E and Alzheimer's Disease: Ethnic Variation in Genotypic Rsks (2004) (1)
- P3-311 Beta-amyloid protein causes impairment of the ubiquitin-proteasome pathway and synaptic plasticity (2004) (0)
- Training Neuropathologists—Two Viewpoints (1981) (0)
- Growth and Trophic Factors. Progress in Clinical and Biological Research, Volume 118 (1983) (0)
- P1-043 UCH-L1 is a critical regulator of synaptic and memory functions following amyloid elevation (2006) (0)
- Biochemistry of Neurofilaments and Neurotubules (2008) (0)
- Neurofibrillary proliferation revisited. (1991) (0)
- 38 DIRECT VISUALIZATION OF THE MICROTUBULES OF LIVING NEURONS (1981) (0)
- Generation of iPSC lines from archived non-cryoprotected biobanked dura mater (2014) (0)
- Robert D. Terry, MDThe Passing of a Titan of Neuropathology (2017) (0)
- Preliminary isolation and fine structure analysis of the Alzheimer neurofilament. (1971) (0)
- Caspase 2 is required for Aβ-induced spine loss (2010) (0)
- The contrasting roles of ICE family proteases and interleukin-1,8 in apoptosis induced by trophic factor withdrawal and by copper/zinc superoxide dismutase down-regulation (oxidative stress/neuronal cells/nerve factor/antisense (2005) (0)
- Heterogeneity of Tubulin Subunits ( sea urchin / Strogylocentrotus / pig brain / acrylamide gel electrophoresis (0)
- Alpha-internexin immunoreactivity: A useful marker in tumors of the pineal region? (1990) (0)
- Antiamyloid therapy—a distant horizon (1989) (0)
- Pol II and P 70S 6 K activation in neuronal apoptosis 1 Functional role of RNA polymerase II and P 70 S 6 kinase in KCl withdrawal-induced cerebellar granule neuron apoptosis (2015) (0)
- The proteins of plaques and tangles: How much do they tell us about the biology of Alzheimer's disease? (1986) (0)
- Apoptosis and its role in Alzheimer’s disease (2002) (0)
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