Michael Meyer-Hermann
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Researcher theoretical biology and university teacher
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Biology
Michael Meyer-Hermann's Degrees
- PhD Theoretical Biology Otto von Guericke University Magdeburg
- Masters Physics Otto von Guericke University Magdeburg
Why Is Michael Meyer-Hermann Influential?
(Suggest an Edit or Addition)According to Wikipedia, Michael Meyer-Hermann is a professor at the Technical University of Braunschweig and head of the department of Systems Immunology at the Helmholtz Centre for Infection Research. Career Meyer-Hermann studied Physics, Mathematics and Philosophy in Frankfurt and Paris. His diploma thesis titled "QCD-Summenregeln mit Massen" about Quantum chromodynamics was published in 1993. In 1997, he finished his doctorate in theoretical Particle Physics at the Goethe University Frankfurt. He founded the research group "Theoretical Biophysics" at the Technical University Dresden in 1998 which he headed until 2003. He worked at the University of Oxford during 2004. From 2005 to 2010, he had the role of a Fellow at the Frankfurt Institute for Advanced Studies . Since 2010, he is a professor at the Technical University of Braunschweig and head of the department of Systems Immunology at the Helmholtz Centre for Infection Research.
Michael Meyer-Hermann's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Germinal Center Dynamics Revealed by Multiphoton Microscopy with a Photoactivatable Fluorescent Reporter (2010) (1026)
- Visualizing antibody affinity maturation in germinal centers (2016) (324)
- Class-Switch Recombination Occurs Infrequently in Germinal Centers. (2019) (256)
- Germinal center B cells govern their own fate via antibody feedback (2013) (239)
- Multicellular tumor spheroid in an off-lattice Voronoi-Delaunay cell model. (2004) (207)
- In Vivo Killing Capacity of Cytotoxic T Cells Is Limited and Involves Dynamic Interactions and T Cell Cooperativity (2016) (180)
- A theory of germinal center B cell selection, division, and exit. (2012) (160)
- An analysis of B cell selection mechanisms in germinal centers. (2006) (136)
- Avian photoreceptor patterns represent a disordered hyperuniform solution to a multiscale packing problem. (2014) (127)
- From Useful Algorithms for Slowly Convergent Series to Physical Predictions Based on Divergent Perturbative Expansions (2007) (119)
- The distinctive germinal center phase of IgE+ B lymphocytes limits their contribution to the classical memory response (2013) (117)
- Modeling Influenza Virus Infection: A Roadmap for Influenza Research (2015) (110)
- Toll-like receptor 4 signaling by follicular dendritic cells is pivotal for germinal center onset and affinity maturation. (2010) (105)
- TFH-derived dopamine accelerates productive synapses in germinal centres (2017) (105)
- Effects of Aging on Influenza Virus Infection Dynamics (2014) (95)
- Recycling probability and dynamical properties of germinal center reactions. (2001) (88)
- Deriving a germinal center lymphocyte migration model from two-photon data (2008) (87)
- Deceleration of Fusion–Fission Cycles Improves Mitochondrial Quality Control during Aging (2012) (82)
- A mathematical model for the germinal center morphology and affinity maturation. (2002) (70)
- Emergence of the Mitochondrial Reticulum from Fission and Fusion Dynamics (2012) (68)
- Novel standards in the measurement of rat insulin granules combining electron microscopy, high-content image analysis and in silico modelling (2012) (66)
- Possible Role of Interleukin-1β in Type 2 Diabetes Onset and Implications for Anti-inflammatory Therapy Strategies (2014) (64)
- Aged insulin granules display reduced microtubule-dependent mobility and are disposed within actin-positive multigranular bodies (2015) (59)
- High SARS-CoV-2 seroprevalence in children and adults in the Austrian ski resort of Ischgl (2020) (58)
- Ebola virus infection modeling and identifiability problems (2015) (57)
- Continuum versus discrete model: a comparison for multicellular tumour spheroids (2006) (55)
- Cutting Edge: Back to “One-Way” Germinal Centers1 (2005) (53)
- Kinetic and dynamic Delaunay tetrahedralizations in three dimensions (2003) (52)
- Development of the reproduction number from coronavirus SARS-CoV-2 case data in Germany and implications for political measures (2020) (51)
- Estimate of the development of the epidemic reproduction number Rt from Coronavirus SARS-CoV-2 case data and implications for political measures based on prognostics (2020) (51)
- Epileptogenesis due to glia-mediated synaptic scaling (2009) (49)
- Interpreting two-photon imaging data of lymphocyte motility. (2005) (48)
- Germinal centres seen through the mathematical eye: B-cell models on the catwalk. (2009) (47)
- Inoculation density and nutrient level determine the formation of mushroom-shaped structures in Pseudomonas aeruginosa biofilms (2016) (45)
- MicroRNA-155 controls affinity-based selection by protecting c-MYC+ B cells from apoptosis. (2016) (43)
- Mathematical modeling of the circadian rhythm of key neuroendocrine-immune system players in rheumatoid arthritis: a systems biology approach. (2009) (42)
- The molecular basis of synergism between carboplatin and ABT-737 therapy targeting ovarian carcinomas. (2011) (42)
- A modelling approach towards epidermal homoeostasis control. (2005) (41)
- Regulatory roles of IL-10–producing human follicular T cells (2019) (41)
- Author Correction: A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals (2020) (37)
- In Silico Analysis of Cell Cycle Synchronisation Effects in Radiotherapy of Tumour Spheroids (2013) (36)
- Spatio-temporal cell dynamics in tumour spheroid irradiation (2010) (36)
- Characterization of CTLA4 Trafficking and Implications for Its Function. (2018) (36)
- The electrophysiology of the beta-cell based on single transmembrane protein characteristics. (2007) (35)
- IR-renormalon contribution to the longitudinal structure function FL (1996) (35)
- Parallel dynamic and kinetic regular triangulation in three dimensions (2005) (34)
- A Spatial Model of Insulin‐Granule Dynamics in Pancreatic β‐Cells (2015) (33)
- Identification of B and T cells in human spleen sections by infrared microspectroscopic imaging (2005) (33)
- Decreased plasma phospholipid concentrations and increased acid sphingomyelinase activity are accurate biomarkers for community-acquired pneumonia (2019) (32)
- Permissive selection followed by affinity-based proliferation of GC light zone B cells dictates cell fate and ensures clonal breadth (2021) (31)
- Overcoming the Dichotomy of Quantity and Quality in Antibody Responses (2014) (28)
- A possible role of chemotaxis in germinal center formation. (2002) (28)
- Induction of broadly neutralizing antibodies in Germinal Centre simulations. (2018) (27)
- Delaunay-Object-Dynamics: cell mechanics with a 3D kinetic and dynamic weighted Delaunay-triangulation. (2008) (26)
- Geometrically Repatterned Immunological Synapses Uncover Formation Mechanisms (2006) (25)
- Cyclin D3 drives inertial cell cycling in dark zone germinal center B cells (2020) (25)
- Modeling emergent tissue organization involving high-speed migrating cells in a flow equilibrium. (2006) (25)
- Injection of Antibodies against Immunodominant Epitopes Tunes Germinal Centers to Generate Broadly Neutralizing Antibodies. (2019) (25)
- A Mathematical Model of Immune Activation with a Unified Self-Nonself Concept (2013) (24)
- Structural Heterogeneity of Mitochondria Induced by the Microtubule Cytoskeleton (2015) (24)
- The common interests of health protection and the economy: evidence from scenario calculations of COVID-19 containment policies (2020) (24)
- Multiscale modeling of cell mechanics and tissue organization (2009) (24)
- A Mathematical Model of T Lymphocyte Calcium Dynamics Derived from Single Transmembrane Protein Properties (2013) (23)
- Signatures of T and B Cell Development, Functional Responses and PD-1 Upregulation After HCMV Latent Infections and Reactivations in Nod.Rag.Gamma Mice Humanized With Cord Blood CD34+ Cells (2018) (21)
- Spatio-Temporal Dynamics of Hypoxia during Radiotherapy (2015) (21)
- F-Actin-Driven CD28-CD80 Localization in the Immune Synapse. (2018) (20)
- Implications of Intravital Imaging of Murine Germinal Centers on the Control of B Cell Selection and Division (2016) (19)
- Multidimensional Analysis Integrating Human T-Cell Signatures in Lymphatic Tissues with Sex of Humanized Mice for Prediction of Responses after Dendritic Cell Immunization (2017) (19)
- How to Simulate a Germinal Center. (2017) (19)
- The F-actin modifier villin regulates insulin granule dynamics and exocytosis downstream of islet cell autoantigen 512 (2016) (18)
- Does recycling in germinal centres exist? (2001) (18)
- Computer Simulation of Multi-Color Brainbow Staining and Clonal Evolution of B Cells in Germinal Centers (2018) (18)
- Assessment of effective mitigation and prediction of the spread of SARS-CoV-2 in Germany using demographic information and spatial resolution (2020) (18)
- The type of seeder cells determines the efficiency of germinal center reactions (2002) (18)
- Antigen Feast or Famine (2012) (17)
- Erratum: IR-renormalon contribution to the polarized structure function g1 (1996) (17)
- A Signal Integration Model of Thymic Selection and Natural Regulatory T Cell Commitment (2014) (16)
- Cell transmembrane receptors determine tissue pattern stability. (2008) (16)
- Cancer therapeutic potential of combinatorial immuno- and vasomodulatory interventions (2015) (16)
- A mathematical model of β‐cells in an islet of Langerhans sensing a glucose gradient (2010) (15)
- Exploiting the Synergy between Carboplatin and ABT-737 in the Treatment of Ovarian Carcinomas (2014) (15)
- Mechanisms of organogenesis of primary lymphoid follicles. (2006) (15)
- PD-1 Blockade Aggravates Epstein–Barr Virus+ Post-Transplant Lymphoproliferative Disorder in Humanized Mice Resulting in Central Nervous System Involvement and CD4+ T Cell Dysregulations (2021) (15)
- Population Dynamics of Borrelia burgdorferi in Lyme Disease (2012) (15)
- Ymir: A 3D structural affinity model for multi-epitope vaccine simulations (2020) (15)
- A quantitative model for presynaptic free Ca2+ dynamics during different stimulation protocols (2002) (14)
- Conclusions from Two Model Concepts on Germinal Center Dynamics and Morphology (2002) (14)
- Case Numbers Beyond Contact Tracing Capacity Are Endangering the Containment of COVID-19. (2020) (14)
- Multiscale Modeling of Germinal Center Recapitulates the Temporal Transition From Memory B Cells to Plasma Cells Differentiation as Regulated by Antigen Affinity-Based Tfh Cell Help (2021) (13)
- A Theory of Plasma Membrane Calcium Pump Stimulation and Activity (2003) (13)
- Innate Immune System Dynamics to Influenza Virus (2012) (13)
- Competition for refuelling rather than cyclic re-entry initiation evident in germinal centers (2022) (13)
- Modelling cellular aggregation induced by chemotaxis and phototaxis. (2010) (13)
- B Cell Speed and B-FDC Contacts in Germinal Centers Determine Plasma Cell Output via Swiprosin-1/EFhd2. (2020) (13)
- The foreshadow of a second wave: An analysis of current COVID-19 fatalities in Germany (2020) (13)
- Functional modules of sigma factor regulons guarantee adaptability and evolvability (2016) (13)
- A concerted Action of B Cell Selection Mechanisms (2007) (13)
- Modeling receptor-ligand binding kinetics in immunological synapse formation (2009) (12)
- Therapeutic Potential of Bacteria against Solid Tumors. (2017) (12)
- Improving personalized tumor growth predictions using a Bayesian combination of mechanistic modeling and machine learning (2021) (12)
- Synchronous Germinal Center Onset Impacts the Efficiency of Antibody Responses (2019) (12)
- Surface reconstruction using Delaunay triangulation for applications in life sciences (2011) (12)
- Repertoire characterization and validation of gB-specific human IgGs directly cloned from humanized mice vaccinated with dendritic cells and protected against HCMV (2020) (12)
- Foxp3+ regulatory T‐cell homeostasis quantitatively differs in murine peripheral lymph nodes and spleen (2015) (11)
- CD2 expression acts as a quantitative checkpoint for immunological synapse structure and T-cell activation (2019) (11)
- Rate of Immune Complex Cycling in Follicular Dendritic Cells Determines the Extent of Protecting Antigen Integrity and Availability to Germinal Center B Cells (2020) (10)
- A mathematical model of the impact of insulin secretion dynamics on selective hepatic insulin resistance (2017) (10)
- Computational Study to Determine When to Initiate and Alternate Therapy in HIV Infection (2014) (9)
- Nitric oxide controls proliferation of Leishmania major by inhibiting the recruitment of permissive host cells (2021) (9)
- On the Immunological Consequences of Conventionally Fractionated Radiotherapy (2020) (9)
- The Quest for System-Theoretical Medicine in the COVID-19 Era (2021) (9)
- Intrinsic defects in lymph node stromal cells underpin poor germinal center responses during aging (2020) (9)
- IR-Renormalon Contribution to the Polarized Structure Function $g_1$ (1996) (8)
- PK/PD-based adaptive tailoring of oseltamivir doses to treat within-host influenza viral infections. (2018) (8)
- A molecular theory of germinal center B cell selection and division. (2021) (8)
- Are T cells at the origin of B cell lymphomas? (2007) (7)
- A least microenvironmental uncertainty principle (LEUP) as a generative model of collective cell migration mechanisms (2018) (7)
- A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals (2020) (7)
- Germinal Centre Shutdown (2021) (7)
- Regional opening strategies with commuter testing and containment of new SARS-CoV-2 variants in Germany (2021) (7)
- Potential benefits of delaying the second mRNA COVID-19 vaccine dose (2021) (6)
- Delaunay Object Dynamics for Tissues Involving Highly Motile Cells (2010) (6)
- Reducing complexity: An iterative strategy for parameter determination in biological networks (2015) (6)
- Differential control of immune cell homeostasis by Foxp3(+) regulatory T cells in murine peripheral lymph nodes and spleen. (2014) (5)
- Modelling Intravital Two-Photon Data of Lymphocyte Migration and Interaction (2011) (5)
- An Adaptive Control Scheme for Interleukin-2 Therapy (2020) (5)
- Evaluation of CD8 T cell killing models with computer simulations of 2-photon imaging experiments (2019) (5)
- Graph-based description of tertiary lymphoid organs at single-cell level (2020) (5)
- On the Impact of Chemo-Mechanically Induced Phenotypic Transitions in Gliomas (2018) (5)
- Entropy-driven cell decision-making predicts ‘fluid-to-solid’ transition in multicellular systems (2020) (4)
- Mathematical Modeling of Synaptic Patterns. (2017) (4)
- A quantitative model for presynaptic free calcium dynamics during the induction of long-term effects (2002) (4)
- Mathematical model shows how sleep may affect amyloid β fibrillization (2019) (4)
- Appropriate relaxation of non-pharmaceutical interventions minimizes the risk of a resurgence in SARS-CoV-2 infections in spite of the Delta variant (2021) (4)
- Mathematical Model Shows How Sleep May Affect Amyloid-β Fibrillization (2020) (4)
- Dynamic Delaunay tetrahedralizations and Voronoi tessellations in three dimensions (2003) (4)
- A 3D structural affinity model for multi-epitope in silico germinal center simulations (2019) (4)
- A minimal modeling framework of radiation and immune system synergy to assist radiotherapy planning. (2019) (4)
- Postprandial Metabolic Effects of Fiber Mixes Revealed by in vivo Stable Isotope Labeling in Humans (2019) (4)
- Estimation of the cancer risk induced by therapies targeting stem cell replication and treatment recommendations (2018) (3)
- BTG1 mutation yields supercompetitive B cells primed for malignant transformation (2023) (3)
- Towards Sub-cellular Modeling with Delaunay Triangulation (2010) (3)
- Coupled Antigen and BLIMP1 Asymmetric Division With a Large Segregation Between Daughter Cells Recapitulates the Temporal Transition From Memory B Cells to Plasma Cells and a DZ-to-LZ Ratio in the Germinal Center (2021) (3)
- Presynaptic Calcium Dynamics of Neurons in Answer to Various Stimulation Protocols (2004) (3)
- Diversity of coupled oscillators can enhance their synchronization. (2016) (3)
- Injection of antibodies against immunodominant epitopes tunes germinal centres to generate broadly neutralizing antibodies (2018) (3)
- Influenza A virus-induced thymus atrophy differentially affects dynamics of conventional and regulatory T cell development (2020) (3)
- Epidermal homeostasis control in an off-lattice agent-based model (2005) (2)
- [The contribution of epidemiological models to the description of the outbreak of the COVID-19 pandemic]. (2021) (2)
- In silico characterization of mechanisms positioning costimulatory and checkpoint complexes in immune synapses (2020) (2)
- Germinal center B cells separate signals for selection and division like compact discs (2020) (2)
- Tingible body macrophages arise from lymph node-resident precursors and uptake B cells by dendrites. (2023) (2)
- MoonFit, a minimal interface for fitting ODE dynamical models, bridging simulation by experimentalists and customization by C++ programmers (2018) (2)
- Estimating the small-x exponent of the structure function g1NS from the Bjorken sum rule (2002) (2)
- Characterization of mechanisms positioning costimulatory complexes in immune synapses (2021) (2)
- Apoptotic cell fragments locally activate tingible body macrophages in the germinal center (2023) (2)
- Author Correction: A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals (2020) (2)
- Recover from non-flippable configurations in parallel approaches to three dimensional kinetic regular triangulations (2006) (1)
- Estimation of the cancer risk induced by therapies targeting stem cell replication and treatment recommendations (2018) (1)
- Agent-Based Modeling of T Cell Receptor Cooperativity (2020) (1)
- COVID-19 in Italy: targeted testing as a proxy of limited health care facilities and a key to reducing hospitalization rate and the death toll. (2020) (1)
- The renormalon contribution to the current product jμ5jS (1999) (1)
- Models of Cell Migration (2012) (1)
- Antibody Mediated Intercommunication of Germinal Centers (2022) (1)
- QCD sum rules with finite masses (1995) (1)
- Modeling bacteria-based therapy in tumor spheroids (2019) (1)
- Bayesian combination of mechanistic modeling and machine learning (BaM3): improving clinical tumor growth predictions (2020) (1)
- Investigating the Mechanism of Germinal Center Shutdown (2022) (1)
- AGENT-BASED MODELS OR DIFFERENTIAL EQUATIONS: TWO WAYS TO LEARN ABOUT SELECTION MECHANISMS IN GERMINAL CENTRES (2008) (1)
- The 16th International Conference on Lymphatic Tissues and Germinal Centers in Immune Responses. (2009) (1)
- Quantitative characterization of CTLA4 trafficking and turnover using a combined in vitro and in silico approach (2017) (1)
- Reprogramming of Amino Acid Metabolism Differs between Community-Acquired Pneumonia and Infection-Associated Exacerbation of Chronic Obstructive Pulmonary Disease (2022) (1)
- In Silico Analysis of the Longevity and Timeline of Individual Germinal Center Reactions in a Primary Immune Response (2021) (1)
- Improving personalized tumor growth predictions using a Bayesian combination of mechanistic modeling and machine learning. (2021) (0)
- The relation of morphology and affinity maturation in germinal centers (2002) (0)
- Amount of antigen, T follicular helper cells and quality of seeder cells shape the diversity of germinal center B cells (2022) (0)
- A Molecular Theory of Germinal Centerb Cell Selection and Division (2020) (0)
- An Agent-Based Model of T Helper Cell Fate Decisions in the Thymus (2021) (0)
- Rescue Ebola Patients in silico (2020) (0)
- Investigating the Physical Effects in Bacterial Therapies for Avascular Tumors (2019) (0)
- Testing and isolation to prevent overloaded healthcare facilities and reduce death rates in the SARS-CoV-2 pandemic in Italy (2022) (0)
- Decreased plasma phospholipid concentrations and increased acid sphingomyelinase activity are accurate biomarkers for community-acquired pneumonia (2019) (0)
- Developing Vaccines For Fast-Evolving Viruses: We Need The Help Of Computers! (2018) (0)
- The actin binding protein villin controls accessibility of insulin granules to their docking sites (2018) (0)
- Multi-Scale Modeling Recapitulates the Effect of Genetic Alterations Associated With Diffuse Large B-Cell Lymphoma in the Germinal Center Dynamics (2022) (0)
- Machine learning identifies immune profile to predict virological relapse after stopping nucleos(t)ide analogue therapy in HBeAg negative chronic hepatitis B (2020) (0)
- Analysis of B cell selection mechanisms in the adaptive immune response (2005) (0)
- CommitmentSelection and Natural Regulatory T Cell A Signal Integration Model of Thymic (2014) (0)
- Mathematical Modeling of T-Cell Electrophysiology (2012) (0)
- Adaptive strategies to contain the COVID 19 epidemic Summary (2020) (0)
- What can we learn on germinal centre reactions from in silico experiments ? (0)
- Understanding repertoire sequencing data through a multiscale computational model of the germinal center (2023) (0)
- The transition between acute and chronic infections in light of energy control: a mathematical model of energy flow in response to infection (2022) (0)
- Presynaptic calcium dynamics of learning neurons (2002) (0)
- From affinity selection to kinetic selection in Germinal Centre modelling (2022) (0)
- ESID: A Visual Analytics Tool to Epidemiological Emergencies (2023) (0)
- Identification of predictive response and resistance factors to targeted therapy in gastric cancer using a systems medicine approach (2016) (0)
- The 16th International Conference on Lymphatic Tissues and Germinal Centers in Immune Responses (2009) (0)
- Correction. (2020) (0)
- Brain geometry matters in Alzheimer’s disease progression: a simulation study (2020) (0)
- Nonuniqueness of the $\lambda\Phi^4$-vacuum (2000) (0)
- T FH -derived dopamine accelerates productive T:B synapses in 1 human germinal centres 2 (2017) (0)
- Addendum to: "On the anomalous dimension for the transversity distribution" (2000) (0)
- Murine Staphylococcus aureus chronic infection is cured by theory-driven therapy (2020) (0)
- A Graph-Based Digital Pathology Approach To Describe Lymphocyte Clustering Patterns After Renal Transplantation (2016) (0)
- Proceedings SY 14 . 02 | Image Analysis III A GRAPH-BASED DIGITAL PATHOLOGY APPROACH TO DESCRIBE LYMPHOCYTE CLUSTERING PATTERNS AFTER RENAL TRANSPLANTATION (2016) (0)
- the Bjorken sum rule (2002) (0)
- A mathematical model of the impact of insulin secretion dynamics on selective hepatic insulin resistance (2017) (0)
- Systemic Lactate Acts as a Metabolic Buffer in Humans and Prevents Nutrient Overflow in the Postprandial Phase (2022) (0)
- Characterization of Mechanisms Positioning Costimulatory and Checkpoint Complexes in Immune Synapses (2021) (0)
- Quality in Antibody Responses Overcoming the Dichotomy of Quantity and (2017) (0)
- In silico predicted therapy against chronic Staphylococcus aureus infection leads to bacterial clearance in vivo (2022) (0)
- Correction: Repertoire characterization and validation of gB-specific human IgGs directly cloned from humanized mice vaccinated with dendritic cells and protected against HCMV (2021) (0)
- Renormalons and Higher-Twist Contributions to Structure Functions (1997) (0)
- Functional Analysis Of Intravital Two-photon Cell Motility Data (2009) (0)
- BTG1 Mutation Promotes Aggressive Lymphoma Development By Lowering the Threshold to MYC Activation and Generating "Super-Competitor" B Cells (2021) (0)
- 00 02 09 5 v 3 2 1 M ay 2 00 1 Non-uniqueness of the λ Φ 4-vacuum (2021) (0)
- THE MASS OF A QUARK–SQUARK BOUND STATE FROM QCD SUM RULES (1999) (0)
- The Chiral odd distribution function h-1: IR renormalon contribution and alpha-s correction (1997) (0)
- The Chiral-Odd Distribution Function h 1 : IR-Renormalon Contribution and α s-Correction (1997) (0)
- Estimation of the cancer risk induced by rejuvenation therapy with young blood and treatment recommendations (2018) (0)
- Amount of antigen, T follicular helper cells and affinity of founder cells shape the diversity of germinal center B cells: A computational study (2023) (0)
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