Michael N. G. James

Michael N. G. James's AcademicInfluence.com Rankings

Michael N. G. James

Earth Sciences

#906

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#1409

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Crystallography

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#12

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earth-sciences Degrees

Michael N. G. James

Mathematics

#5497

World Rank

#7729

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Measure Theory

#764

World Rank

#1023

Historical Rank

mathematics Degrees

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Michael N. G. James's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Crystal structures of the helix-loop-helix calcium-binding proteins. (1989) (772)
Structure of the calcium regulatory muscle protein troponin-C at 2.8 Å resolution (1985) (517)
Molecular structure of the acyl-enzyme intermediate in β-lactam hydrolysis at 1.7 Å resolution (1992) (486)
Structure and refinement of penicillopepsin at 1.8 A resolution. (1983) (372)
Structural evidence for gene duplication in the evolution of the acid proteases (1978) (368)
Structure of Shiga Toxin Type 2 (Stx2) from Escherichia coli O157:H7* (2004) (288)
Picornaviral 3C cysteine proteinases have a fold similar to chymotrypsin-like serine proteinases (1994) (285)
Structural comparison of two serine proteinase-protein inhibitor complexes: eglin-c-subtilisin Carlsberg and CI-2-subtilisin Novo. (1988) (275)
Refined crystal structure of troponin C from turkey skeletal muscle at 2.0 A resolution. (1988) (272)
A model for the Ca2+-induced conformational transition of troponin C. A trigger for muscle contraction. (1986) (270)
Molecular structure of an aspartic proteinase zymogen, porcine pepsinogen, at 1.8 Å resolution (1986) (259)
An algorithm for determining the conformation of polypeptide segments in proteins by systematic search (1986) (246)
Crystallographic Evidence for Substrate-assisted Catalysis in a Bacterial β-Hexosaminidase* (2001) (230)
Calcium-binding sites in proteins: a structural perspective. (1991) (228)
Molecular and crystal structures of monoclinic porcine pepsin refined at 1.8 A resolution. (1990) (226)
Crystal and molecular structure of the serine proteinase inhibitor CI-2 from barley seeds. (1988) (222)
Lysozyme revisited: crystallographic evidence for distortion of an N-acetylmuramic acid residue bound in site D. (1991) (210)
Crystal and molecular structures of the complex of α-chymotrypsin with its inhibitor Turkey ovomucoid third domain at 1.8 Å resolution (1987) (204)
Structure of recombinant human renin, a target for cardiovascular-active drugs, at 2.5 A resolution. (1989) (190)
Structures of product and inhibitor complexes of Streptomyces griseus protease A at 1.8 A resolution. A model for serine protease catalysis. (1980) (188)
Structure of the complex of Streptomyces griseus protease B and the third domain of the turkey ovomucoid inhibitor at 1.8-A resolution. (1983) (188)
Crystal Structures of the RNA-dependent RNA Polymerase Genotype 2a of Hepatitis C Virus Reveal Two Conformations and Suggest Mechanisms of Inhibition by Non-nucleoside Inhibitors* (2005) (187)
The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein (2013) (186)
Crystal structure of human beta-hexosaminidase B: understanding the molecular basis of Sandhoff and Tay-Sachs disease. (2003) (179)
Crystal structure of the holotoxin from Shigella dysenteriae at 2.5 A resolution. (1994) (172)
The POM Monoclonals: A Comprehensive Set of Antibodies to Non-Overlapping Prion Protein Epitopes (2008) (168)
Crystal Structures of Active and Inactive Conformations of a Caliciviral RNA-dependent RNA Polymerase* (2002) (167)
Refined X-ray crystallographic structure of the poliovirus 3C gene product. (1997) (165)
Refined structure of alpha-lytic protease at 1.7 A resolution. Analysis of hydrogen bonding and solvent structure. (1985) (161)
Crystallographic structure of human beta-hexosaminidase A: interpretation of Tay-Sachs mutations and loss of GM2 ganglioside hydrolysis. (2006) (154)
Crystal structure of the holotoxino from Shigella dysenteriae at 2.5 Å resolution (1994) (152)
Non-nucleoside Analogue Inhibitors Bind to an Allosteric Site on HCV NS5B Polymerase (2003) (152)
The refined crystal structure of the 3C gene product from hepatitis A virus: specific proteinase activity and RNA recognition (1997) (149)
The crystal structure of the rhomboid peptidase from Haemophilus influenzae provides insight into intramembrane proteolysis (2007) (149)
Crystal Structures of the Main Peptidase from the SARS Coronavirus Inhibited by a Substrate-like Aza-peptide Epoxide (2005) (148)
The crystal structure of PR3, a neutrophil serine proteinase antigen of Wegener's granulomatosis antibodies. (1996) (146)
Crystal Structure of the Tumor-promoter Okadaic Acid Bound to Protein Phosphatase-1* (2001) (134)
Penicillopepsin from Penicillium janthinellum crystal structure at 2.8 Å and sequence homology with porcine pepsin (1977) (132)
Conformational flexibility in the active sites of aspartyl proteinases revealed by a pepstatin fragment binding to penicillopepsin. (1982) (130)
A potent new mode of β-lactamase inhibition revealed by the 1.7 Å X-ray crystallographic structure of the TEM-1–BLIP complex (1996) (129)
A critical assessment of comparative molecular modeling of tertiary structures of proteins * (1995) (129)
The crystal structure of succinyl-CoA synthetase from Escherichia coli at 2.5-A resolution. (1995) (127)
2-Phenyl-2-(1-hydroxycycloalkyl)ethylamine derivatives: synthesis and antidepressant activity. (1990) (126)
Aspartate 313 in the Streptomyces plicatusHexosaminidase Plays a Critical Role in Substrate-assisted Catalysis by Orienting the 2-Acetamido Group and Stabilizing the Transition State* (2002) (121)
The structure of the 2A proteinase from a common cold virus: a proteinase responsible for the shut‐off of host‐cell protein synthesis (1999) (120)
Crystal structure of human pepsin and its complex with pepstatin (1995) (118)
Stereochemical analysis of peptide bond hydrolysis catalyzed by the aspartic proteinase penicillopepsin. (1985) (117)
Tertiary structural differences between microbial serine proteases and pancreatic serine enzymes (1975) (113)
The molecular structure and catalytic mechanism of a novel carboxyl peptidase from Scytalidium lignicolum. (2004) (113)
Structural details of a calcium-induced molecular switch: X-ray crystallographic analysis of the calcium-saturated N-terminal domain of troponin C at 1.75 A resolution. (1997) (112)
Molecular docking programs successfully predict the binding of a β-lactamase inhibitory protein to TEM-1 β-lactamase (1996) (111)
Rat submaxillary gland serine protease, tonin. Structure solution and refinement at 1.8 A resolution. (1987) (111)
Lowering the entropic barrier for binding conformationally flexible inhibitors to enzymes. (1998) (109)
Refined 1.7 A X-ray crystallographic structure of P-30 protein, an amphibian ribonuclease with anti-tumor activity. (1994) (109)
Crystal and molecular structure of chymotrypsin inhibitor 2 from barley seeds in complex with subtilisin Novo. (1985) (109)
Crystallographic analysis of transition state mimics bound to penicillopepsin: difluorostatine- and difluorostatone-containing peptides. (1994) (109)
Structural and kinetic characterization of a β-lactamase-inhibitor protein (1994) (103)
X-ray crystallography of the binding of the bacterial cell wall trisaccharide NAM-NAG-NAM to lysozyme (1979) (102)
Refined crystal structure of Streptomyces griseus trypsin at 1.7 A resolution. (1988) (96)
The crystal and molecular structures of a cathepsin K:chondroitin sulfate complex. (2008) (96)
Refined structure of porcine pepsinogen at 1.8 A resolution. (1991) (96)
Predicting the reactivity of proteins from their sequence alone: Kazal family of protein inhibitors of serine proteinases. (2001) (93)
Protein structure refinement: Streptomyces griseus serine protease A at 1.8 A resolution. (1979) (92)
Mechanism of acid protease catalysis based on the crystal structure of penicillopepsin (1977) (92)
Crystal structure of sulfide:quinone oxidoreductase from Acidithiobacillus ferrooxidans: insights into sulfidotrophic respiration and detoxification. (2010) (89)
Serine and threonine beta-lactones: a new class of hepatitis A virus 3C cysteine proteinase inhibitors. (2002) (88)
Synthesis and evaluation of keto-glutamine analogues as potent inhibitors of severe acute respiratory syndrome 3CLpro. (2004) (88)
Crystal structures of protein phosphatase-1 bound to motuporin and dihydromicrocystin-LA: elucidation of the mechanism of enzyme inhibition by cyanobacterial toxins. (2006) (83)
Carboxyl–carboxylate interactions in proteins (1982) (83)
Common structural framework of the two Ca2+/Mg2+ binding loops of troponin C and other Ca2+ binding proteins. (1985) (83)
Amino acid sequence alignment of bacterial and mammalian pancreatic serine proteases based on topological equivalences. (1978) (81)
Structure of the complex of Streptomyces griseus proteinase B and polypeptide chymotrypsin inhibitor-1 from Russet Burbank potato tubers at 2.1 A resolution. (1989) (81)
Crystal and molecular structure of the inhibitor eglin from leeches in complex with subtilisin Carlsberg (1985) (81)
The Molecular and Crystal Structure of an Oxindole Alkaloid (6-Hydroxy-2′-(2-methylpropyl)-3,3′-spirotetrahydropyrrolidino-oxindole) (1972) (80)
Non-nucleoside inhibitors binding to hepatitis C virus NS5B polymerase reveal a novel mechanism of inhibition. (2006) (79)
A refinement of the crystal structure of maleic acid (1974) (78)
A detailed structural description of Escherichia coli succinyl-CoA synthetase. (1999) (78)
Comparative molecular model building of two serine proteinases from cytotoxic T lymphocytes (1990) (77)
Critical evaluation of comparative model building of Streptomyces griseus trypsin. (1984) (75)
Water molecules participate in proteinase‐inhibitor interactions: Crystal structures of Leu18, Ala18, and Gly18 variants of turkey ovomucoid inhibitor third domain complexed with Streptomyces griseus proteinase B (1995) (75)
Conversion of the substrate specificity of mouse proteinase granzyme B (1994) (73)
The molecular structure of the complex of Ascaris chymotrypsin/elastase inhibitor with porcine elastase. (1994) (72)
Two trifluoperazine‐binding sites on calmodulin predicted from comparative molecular modeling with troponin‐C (1988) (70)
The Crystal Structure of 1-D-myo-Inosityl 2-Acetamido-2-deoxy-α-D-glucopyranoside Deacetylase (MshB) from Mycobacterium tuberculosis Reveals a Zinc Hydrolase with a Lactate Dehydrogenase Fold* (2003) (70)
Structural insights into stereochemical inversion by diaminopimelate epimerase: an antibacterial drug target. (2006) (69)
Molecular structure of the α-lytic protease from Myxobacter 495 at 2·8 Å resolution☆ (1979) (69)
X-ray crystallographic structure of recombinant eosinophil-derived neurotoxin at 1.83 A resolution. (1996) (66)
Design, synthesis, and evaluation of inhibitors for severe acute respiratory syndrome 3C-like protease based on phthalhydrazide ketones or heteroaromatic esters. (2007) (65)
Structural basis for the inhibition of porcine pepsin by Ascaris pepsin inhibitor-3 (2000) (64)
Crystal structure of the novel aspartic proteinase zymogen proplasmepsin II from Plasmodium falciparum (1999) (63)
Interscaffolding additivity. Association of P1 variants of eglin c and of turkey ovomucoid third domain with serine proteinases. (1997) (62)
Synthesis and evaluation of keto-glutamine analogues as inhibitors of hepatitis A virus 3C proteinase. (2002) (61)
Structural and Functional Characterization of Streptomyces plicatus β-N-Acetylhexosaminidase by Comparative Molecular Modeling and Site-directed Mutagenesis* (1998) (60)
Structural basis of prion inhibition by phenothiazine compounds. (2014) (59)
Structural aspects of activation pathways of aspartic protease zymogens and viral 3C protease precursors. (1999) (59)
Refined crystal structure of the molecular complex of Streptomyces griseus protease B, a serine protease, with the third domain of the ovomucoid inhibitor from turkey. (1982) (59)
Molecular structure of crystalline Streptomyces griseus protease A at 2.8 A resolution. II. Molecular conformation, comparison with alpha-chymotrypsin and active-site geometry. (1978) (59)
Comparison of the solution and X-ray structures of barley serine proteinase inhibitor 2. (1987) (58)
Structure of Arterivirus nsp4 (2002) (56)
Crystal and molecular structures of human progastricsin at 1.62 A resolution. (1995) (55)
The TB Structural Genomics Consortium: a decade of progress. (2011) (55)
Phosphorylated and dephosphorylated structures of pig heart, GTP-specific succinyl-CoA synthetase. (2000) (52)
Effects of disease-modifying anti-rheumatic drugs (DMARDs) on the activities of rheumatoid arthritis-associated cathepsins K and S (2007) (52)
[4]Annulene system. Direct proof for its rectangular geometry (1975) (51)
Model for the interaction of amphiphilic helices with troponin C and calmodulin (1990) (51)
Plant protein proteinase inhibitors: structure and mechanism of inhibition. (2011) (51)
Insights into Mucopolysaccharidosis I from the structure and action of α-L-Iduronidase (2013) (51)
Karplus relation and the correlation of two anomalous carbon-13 vicinal proton coupling constants with bonding electron density distribution found by accurate x-ray analysis (1973) (50)
Towards an understanding of the effects of calcium on protein structure and function (1991) (50)
Molecular dynamics study of the structure and dynamics of a protein molecule in a crystalline ionic environment, Streptomyces griseus protease A. (1990) (49)
Crystallographic analysis of transition-state mimics bound to penicillopepsin: phosphorus-containing peptide analogues. (1993) (48)
Crystal structure of an inhibitor complex of the 3C proteinase from hepatitis A virus (HAV) and implications for the polyprotein processing in HAV. (1999) (47)
Structural insights into the activation of P. vivax plasmepsin. (2003) (47)
Crystal Structures Reveal an Induced-fit Binding of a Substrate-like Aza-peptide Epoxide to SARS Coronavirus Main Peptidase (2006) (46)
Structural Basis of Inhibition Revealed by a 1:2 Complex of the Two-headed Tomato Inhibitor-II and Subtilisin Carlsberg* (2003) (45)
Effect of pH on the activities of penicillopepsin and Rhizopus pepsin and a proposal for the productive substrate binding mode in penicillopepsin. (1984) (45)
Dual Modes of Modification of Hepatitis A Virus 3C Protease by a Serine-derived β-Lactone: Selective Crystallization and Formation of a Functional Catalytic Triad in the Active Site (2005) (44)
Crystal structure of β-hexosaminidase B in complex with pyrimethamine, a potential pharmacological chaperone. (2011) (43)
Crystal structure of LL-diaminopimelate aminotransferase from Arabidopsis thaliana: a recently discovered enzyme in the biosynthesis of L-lysine by plants and Chlamydia. (2007) (43)
ADP-binding site of Escherichia coli succinyl-CoA synthetase revealed by x-ray crystallography. (2000) (43)
The molecular structure of epoxide hydrolase B from Mycobacterium tuberculosis and its complex with a urea-based inhibitor. (2008) (42)
Electron density calculations as an extension of protein structure refinement. Streptomyces griseus protease A at 1.5 A resolution. (1983) (42)
Biochemical and Structural Assessment of the 1-N-Azasugar GalNAc-isofagomine as a Potent Family 20 β-N-Acetylhexosaminidase Inhibitor* (2001) (42)
High throughput crystallography of TB drug targets. (2007) (42)
Molecular docking programs successfully predict the binding of a beta-lactamase inhibitory protein to TEM-1 beta-lactamase. (1996) (42)
The molecular biology of human renin and its gene. (1989) (42)
A Mechanistic View of Enzyme Inhibition and Peptide Hydrolysis in the Active Site of the SARS-CoV 3C-like Peptidase (2007) (41)
Molecular enzymology underlying regulation of protein phosphatase-1 by natural toxins. (2002) (37)
Crystal structure of N-Methyl-N-phenylretinal iminium perchlorate: A structural model for the bacteriorhodopsin chromophore (1990) (37)
Comparison of the predicted model of α-lytic protease with the X-ray structure (1979) (37)
Crystal structure studies and inhibition kinetics of tripeptide chloromethyl ketone inhibitors with Streptomyces griseus protease B. (1980) (37)
Crystal structure of scytalidoglutamic peptidase with its first potent inhibitor provides insights into substrate specificity and catalysis. (2007) (36)
Phosphorylation Status of 72 kDa MMP-2 Determines Its Structure and Activity in Response to Peroxynitrite (2013) (36)
Structure and Function of Picornavirus Proteinases (2002) (35)
Molecular docking identifies the binding of 3-chloropyridine moieties specifically to the S1 pocket of SARS-CoV Mpro (2007) (35)
Structure-Activity Analysis of Cathepsin K/Chondroitin 4-Sulfate Interactions* (2010) (35)
Electrostatic reversal of serine proteinase substrate specificity (1999) (35)
Catalytic residues and substrate specificity of scytalidoglutamic peptidase, the first member of the eqolisin in family (G1) of peptidases (2005) (35)
Regular ArticleRefined Crystal Structure of Rat Parvalbumin, a Mammalian α-lineage Parvalbumin, at 2·0 Å Resolution (1994) (34)
Macrocyclic Inhibitors of Penicillopepsin. 2. X-ray Crystallographic Analyses of Penicillopepsin Complexed with a P3−P1 Macrocyclic Peptidyl Inhibitor and with Its Two Acyclic Analogues (1998) (34)
Crystal structure of diaminopimelate epimerase from Arabidopsis thaliana, an amino acid racemase critical for L-lysine biosynthesis. (2009) (34)
Lysozyme: a model enzyme in protein crystallography. (1996) (34)
X-ray crystallographic analyses of complexes between bovine beta-trypsin and Schiff base copper(II) or iron(III) chelates. (2001) (34)
SQ 14,225: 1-(d-3-mercapto-2-methylpropionyl)-l-proline (1980) (33)
Aryl methylene ketones and fluorinated methylene ketones as reversible inhibitors for severe acute respiratory syndrome (SARS) 3C-like proteinase (2008) (32)
The stereoselective synthesis of aziridine analogues of diaminopimelic acid (DAP) and their interaction with dap epimerase. (2005) (32)
Structure-activity characterization of sulfide:quinone oxidoreductase variants. (2012) (32)
Crystal structure and nucleotide sequence of an anionic trypsin from chum salmon (Oncorhynchus keta) in comparison with Atlantic salmon (Salmo salar) and bovine trypsin. (2002) (30)
Crystalline Modifications of Ampicillin I: the Trihydrate (1968) (30)
Crystal Structure of the Vitamin B12 Biosynthetic Cobaltochelatase, CbiXS, from Archaeoglobus Fulgidus (2006) (30)
Crystal Structure and Mutagenesis of a Protein Phosphatase-1:Calcineurin Hybrid Elucidate the Role of the β12-β13 Loop in Inhibitor Binding* (2004) (30)
The crystal and molecular structure of a potent neuromuscular blocking agent: d-tubocurarine dichloride pentahydrate (1973) (30)
Active Site of α-Lytic Protease (1981) (30)
Binding of adenine to Stx2, the protein toxin from Escherichia coli O157:H7. (2006) (30)
An Episulfide Cation (Thiiranium Ring) Trapped in the Active Site of HAV 3C Proteinase Inactivated by Peptide-based Ketone Inhibitors (2006) (29)
Nucleic acid related compounds. 41. Restricted furanose conformations of 3′,5′-O-(1,1,3,3-tetraisopropyldisilox-1,3-diyl)nucleosides provide a convenient evaluation of anomeric configuration (1983) (29)
X-ray crystal structure of Mycobacterium tuberculosis haloalkane dehalogenase Rv2579. (2008) (29)
The 2.8 A resolution structure of Streptomyces griseus protease B and its homology with alpha-chymotrypsin and Streptomyces griseus protease A. (1979) (28)
Crystallization of a soluble, catalytically active form of Escherichia coli leader peptidase (1995) (28)
The Crystal Structure of Shiga Toxin Type 2 with Bound Disaccharide Guides the Design of a Heterobifunctional Toxin Inhibitor* (2013) (27)
Probing the nucleotide-binding site of Escherichia coli succinyl-CoA synthetase. (1999) (27)
Crystallographic and kinetic investigations of the covalent complex formed by a specific tetrapeptide aldehyde and the serine protease from Streptomyces griseus. (1979) (27)
An X-ray crystallographic approach to enzyme structure and function. (1980) (26)
Structural studies on the folded domain of the human prion protein bound to the Fab fragment of the antibody POM1. (2012) (26)
Comparative modeling of the three‐dimensional structure of the calmodulin‐related TCH2 protein from arabidopsis (1997) (26)
Structural Studies of Histamine H1 Effector Molecules: The Crystal Structure of the Antihistamine Drug (+)-Chlorpheniramine Maleate; [(+)-S-1-(p-Chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpropylamine maleate] (1974) (26)
Molecular mechanisms underlying the interaction of protein phosphatase-1c with ASPP proteins. (2013) (25)
Studies on the Catalytic Mechanism of a Glutamic Peptidase* (2010) (25)
Structural characterization of activation ‘intermediate 2’ on the pathway to human gastricsin (1997) (25)
Contribution of peptide bonds to inhibitor-protease binding: crystal structures of the turkey ovomucoid third domain backbone variants OMTKY3-Pro18I and OMTKY3-psi[COO]-Leu18I in complex with Streptomyces griseus proteinase B (SGPB) and the structure of the free inhibitor, OMTKY-3-psi[CH2NH2+]-Asp19 (2001) (24)
The crystal structure of the arsenite complex of dithiothreitol (1972) (23)
Crystal structure of the yeast cell-cycle control protein, p13suc1, in a strand-exchanged dimer. (1996) (23)
Crystal and molecular structure of [tris(4,5-diisopropylimidazol-2-yl)phosphine]dichlorozinc(II)-bis[N,N-dimethylformamide] (1981) (23)
Mechanism of substrate recognition and PLP-induced conformational changes in LL-diaminopimelate aminotransferase from Arabidopsis thaliana. (2008) (23)
Unbound Form of Tomato Inhibitor-II Reveals Interdomain Flexibility and Conformational Variability in the Reactive Site Loops* (2003) (23)
Aspartic proteinases : retroviral and cellular enzymes (1998) (23)
Catalytic pathway of aspartic peptidases (2004) (23)
Crystal structure of a flavoprotein related to the subunits of bacterial luciferase. (1993) (23)
A dimeric form of Escherichia coli succinyl-CoA synthetase produced by site-directed mutagenesis. (1999) (23)
Why does pepsin have a negative charge at very low pH? An analysis of conserved charged residues in aspartic proteinases. (1991) (22)
Transition of the prion protein from a structured cellular form (PrPC) to the infectious scrapie agent (PrPSc) (2019) (22)
Anchimeric assistance in hexosaminidases (2002) (22)
Accurate dimensions of the maleate mono-anion in a symmetric environment not dictated by crystallographic symmetry: imidazolium maleate (1976) (22)
Dynamics of catalysis revealed from the crystal structures of mutants of diaminopimelate epimerase. (2007) (22)
Structural refinement of the non-fluorescent flavoprotein from Photobacterium leiognathi at 1.60 A resolution. (1995) (22)
Crystal structure of N-acetyl-gamma-glutamyl-phosphate reductase from Mycobacterium tuberculosis in complex with NADP(+). (2006) (21)
The molecular and crystal structure of disodium uridine‐3'‐phosphate tetrahydrate (1972) (21)
X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins. (2015) (21)
Comparative NMR studies on cardiac troponin C and a mutant incapable of binding calcium at site II. (1991) (21)
Structural study of the complex between human pepsin and a phosphorus-containing peptidic -transition-state analog. (2000) (20)
Crystal and molecular structures of the complex of alpha-chymotrypsin with its inhibitor turkey ovomucoid third domain at 1.8 A resolution. (1987) (20)
Thermodynamic criterion for the conformation of P1 residues of substrates and of inhibitors in complexes with serine proteinases. (1999) (19)
Structure of the subtilisin Carlsberg-OMTKY3 complex reveals two different ovomucoid conformations. (2005) (19)
The molecular structure of Rv2074, a probable pyridoxine 5'-phosphate oxidase from Mycobacterium tuberculosis, at 1.6 angstroms resolution. (2006) (19)
The crystal structures of ornithine carbamoyltransferase from Mycobacterium tuberculosis and its ternary complex with carbamoyl phosphate and L-norvaline reveal the enzyme's catalytic mechanism. (2008) (19)
Molecular structure of crystalline Streptomyces griseus protease A at 2.8 A resolution. I. Crystallization, data collection and structural analysis. (1978) (19)
Comparative molecular modeling and crystallization of P‐30 protein: A novel antitumor protein of Rana pipiens oocytes and early embryos (1992) (19)
Molecular structure of troponin C and its implications for the Ca2+ triggering of muscle contraction. (1987) (18)
The structure of LL-diaminopimelate aminotransferase from Chlamydia trachomatis: implications for its broad substrate specificity. (2011) (18)
Heteroaromatic ester inhibitors of hepatitis A virus 3C proteinase: Evaluation of mode of action (2008) (18)
The molecular structure of ornithine acetyltransferase from Mycobacterium tuberculosis bound to ornithine, a competitive inhibitor. (2010) (17)
Structures of Mycobacterium tuberculosis pyridoxine 5′‐phosphate oxidase and its complexes with flavin mononucleotide and pyridoxal 5′‐phosphate (2005) (16)
The structures of Thermoplasma volcanium phosphoribosyl pyrophosphate synthetase bound to ribose-5-phosphate and ATP analogs. (2011) (16)
Calcium binding to skeletal muscle troponin C and the regulation of muscle contraction. (2007) (16)
Deleterious effects of β‐branched residues in the S1 specificity pocket of Streptomyces griseus proteinase B (SGPB): Crystal structures of the turkey ovomucoid third domain variants Ile18I, Val18I, Thr18I, and Ser18I in complex with SGPB (2008) (15)
The 4.5 Å Resolution Structure of a Bacterial Serine Protease from Streptomyces Griseus (1974) (15)
Crystal structure of the arginine repressor protein in complex with the DNA operator from Mycobacterium tuberculosis. (2008) (15)
Separation of porcine pepsinogen A and progastricsin. Sequencing of the first 73 amino acid residues in progastricsin. (1992) (15)
Chemistry of micrococcin P. IX. The crystal and molecular structure of micrococcinic acid bis-4-bromoanilide. (1966) (15)
Common structural features of the luxF protein and the subunits of bacterial luciferase: Evidence for a (βα)8 fold in luciferase (1994) (15)
Purification and crystallization of Shiga toxin from Shigella dysenteriae. (1993) (15)
A crystallographic re-investigation into the structure of Streptomyces griseus proteinase A reveals an acyl-enzyme intermediate. (1994) (14)
Site-directed mutagenesis of histidine 69 and glutamic acid 148 alters the ribonuclease activity of pea ABR17 (PR10.4). (2011) (14)
Pig heart CoA transferase exists as two oligomeric forms separated by a large kinetic barrier. (2000) (14)
The structure of the arginine repressor from Mycobacterium tuberculosis bound with its DNA operator and Co-repressor, L-arginine. (2009) (14)
Crystallization of succinyl-CoA synthetase from Escherichia coli. (1984) (13)
Cloning, expression, purification, crystallization and preliminary X-ray studies of epoxide hydrolases A and B from Mycobacterium tuberculosis. (2006) (13)
Penicillopepsin: 2.8 A structure, active site conformation and mechanistic implications. (1977) (13)
The crystal structure of Rv0793, a hypothetical monooxygenase from M.␣tuberculosis (2006) (13)
A charge-transfer complex: bis(2,4,6-trimethyl-1-pyridyl)iodonium perchlorate (1982) (13)
Cysteine proteases: evolution, function, and inhibitor design. (1996) (13)
Structural and kinetic characterization of a beta-lactamase-inhibitor protein. (1994) (12)
Crystal structure of dl-brompheniramine maleate (1-(p-bromophenyl)-1-(2-pyridyl)-3-N,N-dimethylpropylamine maleate). (1971) (12)
X-ray diffraction studies on penicillopepsin and its complexes: the hydrolytic mechanism (1985) (12)
Structural insights for the substrate recognition mechanism of LL-diaminopimelate aminotransferase. (2011) (11)
1.2A-resolution crystal structures reveal the second tetrahedral intermediates of streptogrisin B (SGPB). (2008) (11)
The crystal and molecular structure of disodium maleate monohydrate (1974) (11)
Crystal structure of Mycobacterium tuberculosis Rv0760c at 1.50 A resolution, a structural homolog of Delta(5)-3-ketosteroid isomerase. (2008) (11)
Crystal structure of gamma-chymotrypsin in complex with 7-hydroxycoumarin. (2001) (11)
Computational analysis of the binding of P1 variants of domain 3 of turkey ovomucoid inhibitor to Streptomyces griseus protease B. (1998) (10)
Structural and functional characterization of Streptomyces plicatus beta-N-acetylhexosaminidase by comparative molecular modeling and site-directed mutagenesis. (1998) (10)
Refined crystal structure of rat parvalbumin, a mammalian alpha-lineage parvalbumin, at 2.0 A resolution. (1994) (10)
The peptidases from fungi and viruses (2006) (10)
Crystallographic data for troponin C from turkey skeletal muscle. (1984) (10)
Proteolytic Enzymes of the Viruses of the Family Picornaviridae (1999) (10)
On the bond distance between bromine and aromatic carbon atoms (1973) (10)
Synthesis of pseudoxazolones and their inhibition of the 3C cysteine proteinases from hepatitis A virus and human rhinovirus-14 (2002) (10)
Crystal structure of 2,4-diselenouracil. (1966) (10)
RELATIONSHIP BETWEEN THE STRUCTURES AND ACTIVITIES OF SOME MICROBIAL SERINE PROTEASES. II. COMPARISON OF THE TERTIARY STRUCTURES OF MICROBIAL AND PANCREATIC SERINE PROTEASES (1976) (9)
Crystallographic structure of human beta-Hexosaminidase A (2006) (9)
Structural insights into the non-additivity effects in the sequence-to-reactivity algorithm for serine peptidases and their inhibitors. (2007) (9)
Crystal structure of human pepsinogen A. (1998) (9)
The structure of pilocarpine hydrochloride, C11H17N2O2+.Cl−: a muscarinic alkaloid (1984) (9)
The Crystal and Molecular Structure of the Antihistaminic Drug Triprolidine Hydrochloride Monohydrate [trans-1-(p-Tolyl)-1-(2-pyridyl)-3-(1-pyrrolidino)-prop-1-ene] (1974) (9)
Crystallization of human β-hexosaminidase B (1992) (9)
Structure of the C-terminal domain of the arginine repressor protein from Mycobacterium tuberculosis. (2008) (9)
Crystal structure of the intermediate complex of the arginine repressor from Mycobacterium tuberculosis bound with its DNA operator reveals detailed mechanism of arginine repression. (2010) (8)
The molecular geometry of 2',3'-dideoxy-2',3'-didehydroadenosine from an X-ray crystal structure determination (1974) (8)
The crystal structure of an octapeptide repeat of the Prion protein in complex with a Fab fragment of the POM2 antibody (2013) (8)
Crystal Data for a Bacterial Serine Protease (1969) (8)
Crystallization and preliminary X-ray diffraction analysis of prion protein bound to the Fab fragment of the POM1 antibody. (2011) (8)
The crystal and molecular structures of 2,2'-anhydro-1-β-d-arabino-furanosyl uracil (1973) (8)
Molecular structure of the alpha-lytic protease from Myxobacter 495 at 2.8 Angstroms resolution. (1979) (8)
An algorithm which predicts the conformation of short lengths of chain in proteins (1986) (8)
ChemInform Abstract: Serine and Threonine β-Lactones: A New Class of Hepatitis A Virus 3C Cysteine Proteinase Inhibitors. (2002) (7)
Crystal Structure of Human β-Hexosaminidase B: Understanding the Molecular Basis of Sandhoff and Tay–Sachs Disease (2018) (7)
Molecular conformation of (+)-tubocurarine chloride, a mono-quaternary curare alkaloid (1972) (7)
The 3C Proteinases of Picornaviruses and Other Positive-Sense, Single-Stranded RNA Viruses (2000) (7)
Preliminary X-ray crystallographic analysis of sulfide:quinone oxidoreductase from Acidithiobacillus ferrooxidans. (2009) (7)
HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE GENOTYPE 2a (2005) (7)
Hepatitis A virus 3C proteinase: some properties, crystallization and preliminary crystallographic characterization. (1993) (6)
Crystallization of glycogen debranching enzyme. (1984) (6)
The molecular structure of gutierolide, a novel chloro-diterpenoid lactone (1971) (6)
REFINED CRYSTAL STRUCTURE OF TROPONIN C FROM TURKEY SKELETAL MUSCLE AT 2.0 ANGSTROMS RESOLUTION (1988) (6)
Characterization of the phosphoserine of pepsinogen using 31P nuclear magnetic resonance: corroboration of X-ray crystallographic results. (1986) (6)
The Molecular Conformation of 1e,2a,6e-Trimethyl-4e-phenyl-4a-acetoxypiperidine Hydrobomide in the Crystalline State (1973) (6)
Structural characterization of POM6 Fab and mouse prion protein complex identifies key regions for prions conformational conversion (2018) (6)
Crystallographic Analysis of a Pepstatin Analogue Binding to the Aspartyl Proteinase Penicillopepsin at 1.8 Angstroms Resolution (1994) (5)
Crystallographic determination of lanthanide ion binding to troponin C (1986) (5)
Structural Studies of Histamine RB Effector Molecules: The Crystal Structure of the Antihistaminic Drug (+)-Chlorpheniramine Maleate; (1974) (5)
Crystal data for tonin, an enzyme involved in the formation of angiotensin II. (1978) (5)
X-ray crystallographic studies of the complex between porcine pepsin and the aspartic proteinase inhibitor PI-3 from the nematode Ascaris suum. (1998) (5)
The crystal structure of 2,2'-anhydro-2-hydroxy-1-(β-d-arabino-pentofuranosyl)4-pyridone (1977) (5)
A Detailed Structural Description of Escherichia coli (1999) (5)
The crystal and molecular structure of 2,5'-anhydro-2',3'-isopropylidene cyclouridine (1974) (4)
Pseudoxazolones, a new class of inhibitors for cysteine proteinases: inhibition of hepatitis A virus and human rhinovirus 3C proteinases (2001) (4)
Preliminary X-ray crystallographic analysis of ornithine acetyltransferase (Rv1653) from Mycobacterium tuberculosis. (2009) (4)
Shiga toxin type 2 (2004) (4)
Crystallization of Photobacterium leiognathi non-fluorescent flavoprotein, an unusual flavoprotein with limited sequence identity to bacterial luciferase. (1992) (4)
Molecular biology of human renin and its gene. (1991) (4)
Overcoming the unfavourable entropic contribution of ligand binding with a macrocyclic inhibitor bound to penicillopepsin. (1998) (4)
The molecular and crystal structure of N-(-D-ribofuranosyl)imidazole (1973) (4)
Expression, purification and preliminary X-ray analysis of the C-terminal domain of an arginine repressor protein from Mycobacterium tuberculosis. (2007) (4)
Expression, purification and preliminary crystallographic analysis of Rv3002c, the regulatory subunit of acetolactate synthase (IlvH) from Mycobacterium tuberculosis. (2011) (3)
Preliminary crystallographic data for the serine protease inhibitor CI-2 from barley seeds. (1983) (3)
Crystal structure of the yeast cell-cycle control protein, P13suc1, in a strand-exchanged dimer (1996) (3)
Expression, purification, crystallization and preliminary X-ray analysis of two arginine-biosynthetic enzymes from Mycobacterium tuberculosis. (2006) (3)
The crystal structure of 3‐deazacytidine (1977) (3)
Crystal structure of sulfide:quinone oxidoreductase from Acidithiobacillus ferrooxidans (2010) (3)
Expression, purification and preliminary crystallographic analysis of Rv2247, the β subunit of acyl-CoA carboxylase (ACCD6) from Mycobacterium tuberculosis. (2011) (3)
Conformational flexibility in the third domain of the turkey ovomucoid inhibitor bound to SGPB and α-chymotrypsin (1984) (3)
The crystal structure of penicillopepsin at 6Åresolution (1976) (3)
Expression, purification and preliminary crystallographic analysis of O-acetylhomoserine sulfhydrylase from Mycobacterium tuberculosis. (2011) (3)
The molecular structure of human progastricsin and its comparison with that of porcine pepsinogen. (1995) (3)
A detailed description of the structure of Succinyl-COA synthetase from Escherichia coli (1999) (3)
Structure of the Mengo virion. VII. Crystallization and preliminary X-ray diffraction analysis. (1984) (3)
Crystal structure of LL-Diaminopimelate Aminotransferase from Arabidopsis thaliana complexed with L-malate ion (2007) (2)
Active site of alpha-lytic protease: enzyme-substrate interactions. (1981) (2)
Crystal structure of LL-Diaminopimelate Aminotransferase from Arabidopsis thaliana (2007) (2)
Expression, purification and preliminary crystallographic analysis of N-acetylglucosamine-1-phosphate uridylyltransferase from Mycobacterium tuberculosis. (2008) (2)
CONFORMATIONAL FLEXIBILITY OF TROPONIN C11Supported by the Medical Research Council of Canada, an Alberta Heritage Foundation of Medical Research Fellowship (to O.H.) and an Alberta Heritage Foundation for Medical Research Visiting Scientist Fellowship (to J.M.). (1987) (2)
Structure of arterivirus nsp4-The smallest chymotrypsin- like protease with an / -C-terminal extension and alternate conformations of the oxyanion hole (2008) (2)
Structures of Mycobacterium tuberculosispyridoxine 5'-phosphate oxidase and its complexes with flavin mononucleotide and pyridoxal 5'-phosphate. (2005) (2)
P13SUC1 IN A STRAND-EXCHANGED DIMER (1996) (2)
Structure of (+)-(5R,6R)-5-chloro-6-methoxy-5,6-dihydro-1-(2',3'-didehydro-2',3'-dideoxy-β-d-glycero-2-enopentofuranosyl)thymine (1993) (2)
Studies on Glycogen Phosphorylase in Solution and in the Crystalline State (1972) (2)
Expression, purification, crystallization and preliminary X-ray analysis of Rv3117, a probable thiosulfate sulfurtransferase (CysA3) from Mycobacterium tuberculosis. (2008) (2)
Synthesis and Evaluation of Keto-Glutamine Analogues as Inhibitors of Hepatitis A Virus 3 C Proteinase (2)
Structure of (+)‐(5R,6R)‐5‐Chloro‐6‐methoxy‐5,6‐dihydro‐1‐(2′,3′‐ didehydro‐2′,3′‐dideoxy‐β‐D‐glycero‐2‐enopentofuranosyl)thymine (1993) (1)
The molecular structure of Rv1873, a conserved hypothetical protein from Mycobacterium tuberculosis, at 1.38 A resolution. (2006) (1)
Racemic isopropyl 1,4-dihydro-2,6-dimethyl-4-(6-methyl-2-pyridyl)-3- nitropyridine-5-carboxylate hemibenzene solvate. (2000) (1)
Application of translation functions to the direct methods solution of an unknown structure (1973) (1)
1,2-Dimethyl-4-hydroxy-4-phenylpiperidine hydrochloride (1974) (1)
Structure of N‐ethylmaleimide, C6H7NO2 (1983) (1)
Structure of 1-(2-deoxy-β-D-ribofuranosyl)-5-[(1S)-2,2-dibromocyclopropyl]uracil (1989) (1)
Structure determination of Ascaris pepsin inhibitor-3 by MAD phasing (2000) (1)
Crystal structure of an active-site model for carbonic anhydrase: [tris-2(4,5-diisopropylimidazolyl)phosphine]dichlorozinc(II).Â·2[N,N-dimethylformamide] (1981) (1)
Insights into the mutations that cause mucopolysaccharidosis I (MPS I) based on the structure and mechanism of α-l-iduronidase (2013) (1)
COMPARATIVE MOLECULAR MODELLING OF THE Ca++ SENSITIVE REGULATORY PROTEIN CALMODULIN BASED ON TURKEY SKELETAL TNC (1987) (1)
Viral Cysteine Peptidases and Cysteine Peptidase Inhibitors (2008) (1)
Analysis and prediction of solvent structures in protein crystals (1984) (1)
(E)-1-(2'-deoxy-beta-D-ribofuranosyl)-2,4-difluoro-5-(2-iodovinyl)benzene. (2001) (1)
Crystal structure of sulfide:quinone oxidoreductase Ser126Ala variant from Acidithiobacillus ferrooxidans (2012) (1)
Handbook of proteolytic enzymes, edited by A. J. Barrett, N. D. Rawlings, and J. F. Woessner. 1998. London: Academic Press. 1666 pp. $250.00. $90.00 for the CD-ROM (2008) (1)
CRYSTAL STRUCTURE OF SGPB:OMTKY3-COO-LEU18I (2001) (1)
Crystal Structure of the Subtilisin Carlsberg:OMTKY3 Complex (2005) (1)
The crystal structure of the cathepsin K Variant M5 in complex with chondroitin-4-sulfate (2010) (1)
Crystal structure of HAV 3C protease complexed with a β-lactone inhibitor: a new crystal form of HAV 3C and its application for studying enzyme-inhibitor interaction (2005) (1)
Crystal structure of Human Cathepsin K in complex with myocrisin (2006) (1)
The crystal structure of troponin C from turkey skeletal muscle at 2.8 Ã resolution (1984) (1)
1‐Methyl‐5‐fluoro‐6‐methoxy‐5,6‐dihydrouracil (1976) (1)
CRYSTAL STRUCTURE OF DEPHOSPHORYLATED PIG HEART, GTP-SPECIFIC SUCCINYL-COA SYNTHETASE (2000) (0)
ACID PROTEINASE (PENICILLOPEPSIN) (E.C.3.4.23.20) COMPLEX WITH PHOSPHONATE INHIBITOR: METHYL (2S)-[1-(((N-FORMYL)-L-VALYL)AMINO-2-(2-NAPHTHYL)ETHYL) HYDROXYPHOSPHINYLOXY]-3-PHENYLPROPANOATE, SODIUM SALT (1998) (0)
CRYSTAL STRUCTURE OF DEPHOSPHORYLATED E. COLI SUCCINYL-COA SYNTHETASE (2000) (0)
Crystal structure of the C217S mutant of diaminopimelate epimerase (2007) (0)
ChemInform Abstract: Synthesis of Pseudoxazolones and Their Inhibition of the 3C Cysteine Proteinases from Hepatitis A Virus and Human Rhinovirus-14. (2002) (0)
Crystal structure of the C-terminal domain hexamer of ArgR from Mycobacterium tuberculosis (2008) (0)
Molecular basis for Tay-Sachs revealed by the crystal structure of human β-hexosaminidaseA (2005) (0)
Poliovirus 3C protease crystallization and structure solution (1996) (0)
Anionic Trypsin from Pacific Chum Salmon (2002) (0)
Crystal structure of hypothetical protein af0721 from Archaeoglobus fulgidus (2004) (0)
ASP 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 10.7 (2003) (0)
Crystal Structure of Ornithine Carbamoyltransferase from Mycobacterium Tuberculosis (Rv1656): Orthorhombic Form (2007) (0)
Crystal structure of GlpG, Rhomboid Peptidase from Haemophilus influenzae (2006) (0)
Non-nucleoside inhibitors of NS5B polymerase from HCV, genotypes 1b and 2a (2005) (0)
X-ray crystal structure of mycobacterium tuberculosis pyridoxine 5'-phosphate oxidase complexed with flavin mononucleotide at 2.2 a resolution (2005) (0)
CRYSTAL STRUCTURE OF ASCARIS PEPSIN INHIBITOR-3 (2001) (0)
Crystal Structure of Ornithine Carbamoyltransferase complexed with Carbamoyl Phosphate and L-Norvaline from Mycobacterium tuberculosis (Rv1656) at 2.2 A (2007) (0)
THE (4)ANNULENE SYSTEM, DIRECT PROOF FOR ITS RECTANGULAR GEOMETRY (1975) (0)
Molecular structures of the complexes of SGPB with OMTKY3 aromatic P1 variants Trp18I, His18I, Phe18I, and Tyr18I (2006) (0)
Crystal Structure of the Complex of ADP and MG2+ with Dephosphorylated E. Coli Succinyl-CoA Synthetase (2000) (0)
Structural Basis of Prion Protein Conformation Conversion Inhibition (2014) (0)
Crystal structure of apo-LL-diaminopimelate aminotransferase from Arabidopsis thaliana (no PLP) (2008) (0)
CRYSTAL STRUCTURE OF TEM-1 BETA-LACTAMASE / BETA-LACTAMASE INHIBITOR PROTEIN COMPLEX (2001) (0)
CALMODULIN-TYPE TCH2 PROTEIN FROM ARABIDOPSIS, THEORETICAL MODEL (1998) (0)
ACID PROTEINASE (PENICILLOPEPSIN) COMPLEX WITH PHOSPHONATE INHIBITOR. (1998) (0)
Human lysosomal beta-hexosaminidase isoform B in complex with intermediate analogue NAG-thiazoline (2003) (0)
X-ray crystal structure of RV0760c from Mycobacterium tuberculosis at 2.10 Angstrom resolution (2007) (0)
Prediction of the conformation of short segments of polypeptide chain in proteins (1987) (0)
MIRAS phasing of the crystal structure of the glycogen debranching enzyme from mammalian muscle (1996) (0)
Crystal structure of sulfide:quinone oxidoreductase Cys128Ala variant from Acidithiobacillus ferrooxidans complexed with decylubiquinone (2012) (0)
Crystal structure of diaminopimelate epimerase from Arabidopsis thaliana in complex with LL-AziDAP (2009) (0)
Crystal structure of SARS coronavirus main peptidase (with an additional Ala at the N-terminus of each protomer) in the space group P43212 (2006) (0)
Crystal structure of the C-terminal domain hexamer of ArgR from Mycobacterium tuberculosis in complex with arginine (2008) (0)
Native human lysosomal beta-hexosaminidase isoform B (2003) (0)
LYS 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH ALPHA-CHYMOTRYPSIN (1998) (0)
ACID PROTEINASE (PENICILLOPEPSIN) (E.C.3.4.23.20) COMPLEX WITH PHOSPHONATE INHIBITOR: METHYL(2S)-[1-(((N-(1-NAPHTHALENEACETYL))-L-VALYL)AMINOMETHYL)HYDROXY PHOSPHINYLOXY]-3-PHENYLPROPANOATE, SODIUM SALT (1998) (0)
THE KARPLUS RELATIONSHIP AND THE CORRELATION OF TWO ANOMALOUS (13)C-VICINAL (1)H COUPLING CONSTANTS WITH BONDING ELECTRON DENSITY DISTRIBUTION FOUND BY ACCURATE X-RAY ANALYSIS (1974) (0)
Crystal structure of the P. vivax aspartic proteinase plasmepsin complexed with the inhibitor pepstatin A (1999) (0)
REFINED STRUCTURE OF PORCINE PEPSINOGEN AT 1.8 ANGSTROMS RESOLUTION (1992) (0)
Crystal structure of apo-iduronidase in the R3 form (2013) (0)
The crystal structure of Stx2 and a disaccharide ligand (2013) (0)
Crystal structure of the arginine repressor protein from Mycobacterium tuberculosis in complex with the DNA operator (2008) (0)
Structure of an octapeptide repeat of the prion protein bound to the POM2 Fab antibody fragment (2013) (0)
The structural basis for Ser/Thr protein phosphatase inhibition (2005) (0)
Crystal Structure of Beta-Lactamse Inhibitory Protein-I (BLIP-I) in Apo Form (2009) (0)
POLIOVIRUS 3C PROTEINASE (2002) (0)
Human iduronidase apo structure P21 form (2013) (0)
Comparison of the predicted model of alpha-lytic protease with the x-ray structure. (1979) (0)
Protein inhibitors of subtilisins A structural comparison (1995) (0)
Using the 3D structures of the viral proteinases of porcine epidemic diarrhoea virus (PEDV) to design anti-PEDV drugs (2018) (0)
Crystal structure of sulfide:quinone oxidoreductase Ser126Ala variant from Acidithiobacillus ferrooxidans using 7.0 keV diffraction data (2012) (0)
Crystal structure of mouse prion protein complexed with Chlorpromazine (2014) (0)
Crystal structure of proplasmepsin from the human malarial pathogen Plasmodium vivax (2002) (0)
Crystal structure of K270N variant of LL-diaminopimelate aminotransferase from Arabidopsis thaliana complexed with LL-DAP: External aldimine form (2008) (0)
Crystal structure of human alpha-L-iduronidase complex with [2R,3R,4R,5S]-2-carboxy-3,4,5-trihydroxy-piperidine (2013) (0)
Hepatitis C virus RNA polymerase in complex with non-nucleoside analogue inhibitor (2003) (0)
The mechanism of activation of porcine pepsinogen (reply) (1986) (0)
Unbound form of Tomato Inhibitor-II (2003) (0)
PROPLASMEPSIN II FROM PLASMODIUM FALCIPARUM (1999) (0)
Structure of SCP-B the first member of the Eqolisin family of Peptidases to have its structure determined (2004) (0)
Crystal structure of human pepsinogen A (1996) (0)
Pseudoxazolones, a New Class of Inhibitors for Cysteine Proteinases: Inhibition of Hepatitis A Virus and Human Rhinovirus 3C Proteinases. (2002) (0)
X-ray Crystal Structure of dihydromicrocystin-LA bound to Protein Phosphatase-1 (2006) (0)
Crystal structure of N-Acetyl-gamma-Glutamyl-Phosphate Reductase (Rv1652) from Mycobacterium tuberculosis at 1.58 A resolution (2006) (0)
Structure of POM1 FAB fragment complexed with human PrPc Fragment 120-230 (2012) (0)
Crystal structure of Syrian hamster prion protein complexed with POM1 FAB (2015) (0)
Table of Contents (1993) (0)
The Crystal Structure of Ornithine Acetyltransferase complexed with Ornithine from Mycobacterium tuberculosis (Rv1653) at 2.4 A (2010) (0)
STRUCTURAL COMPARISONS OF TWO SERINE PROTEINASE(COLON)*PROTEIN INHIBITOR COMPLEXES-EGLIN-C(COLON)*SUBTILISIN CARLSBERG AND /CI$-2(COLON)*SUBTILISIN NOVO (1988) (0)
Crystal structure of Scytalido-glutamic peptidase with a peptide based transition state analog (2006) (0)
ACID PROTEINASE (PENICILLOPEPSIN) (E.C.3.4.23.20) COMPLEX WITH PHOSPHONATE INHIBITOR: METHYL(2S)-[1-(((N-FORMYL)-L-VALYL)AMINO-2-(2-NAPHTHYL)ETHYL)HYDROXYPHOSPHINYLOXY]-3-PHENYLPROPANOATE, SODIUM SALT (1998) (0)
CRYSTAL COMPLEX OF THE 3C PROTEINASE FROM HEPATITIS A VIRUS WITH ITS INHIBITOR AND IMPLICATIONS FOR THE POLYPROTEIN PROCESSING IN HAV (1999) (0)
Human lysosomal beta-hexosaminidase isoform B in complex with (2R,3R,4S,5R)-2-Acetamido-3,4-Dihydroxy-5-Hydroxymethyl-Piperidinium Chloride (GalNAc-isofagomine) (2003) (0)
Crystal structure of N-Acetyl-gamma-Glutamyl-Phosphate Reductase (Rv1652) from Mycobacterium tuberculosis (2006) (0)
Crystal structure of sulfide:quinone oxidoreductase Cys128Ala variant from Acidithiobacillus ferrooxidans with bound trisulfane (2012) (0)
The Crystal Structure of beta-hexosaminidase B in complex with Pyrimethamine (2011) (0)
ACID PROTEINASE (PENICILLOPEPSIN) (E.C.3.4.23.20) COMPLEX WITH PHOSPHONATE INHIBITOR: METHYL CYCLO[(2S)-2-[[(1R)-1-(N-(L-N-(3-METHYLBUTANOYL)VALYL-L-ASPARTYL)AMINO)-3-METHYLBUT YL] HYDROXYPHOSPHINYLOXY]-3-(3-AMINOMETHYL) PHENYLPROPANOATE (1998) (0)
The crystal structure of the complex of porcine pancreatic elastase with C/E-1 inhibitor, a member of a novel inhibitor family of serine proteinases (1993) (0)
Theoretical Studies of the Energetics and Dynamics of the Aqueous and Ionic Environment about Proteins: Crystals of Streptomyces Griseus Protease A (1989) (0)
Structural studies of conformationally-restricted ligands binding to aspartic peptidases. (2017) (0)
COMPLEX OF ASCARIS CHYMOTRPSIN/ELASTASE INHIBITOR WITH PORCINE ELASTASE (1999) (0)
Crystal structure of the second tetrahedral intermediates of SGPB at pH 4.2 (2007) (0)
X-ray crystal structure of mycobacterium tuberculosis pyridoxine 5'-phosphate oxidase at 1.8 a resolution (2004) (0)
Crystal Structure of Rabbit Hemorrhagic Disease Virus RNA-dependent RNA polymerase complexed with Lu3+ (2002) (0)
Crystal structure of sulfide:quinone oxidoreductase Cys356Ala variant from Acidithiobacillus ferrooxidans complexed with decylubiquinone (2012) (0)
Dual modes of modification of Hepatitis A virus 3C protease by a serine derived beta-lactone: selective crytstallization and high resolution structure of the His102 adduct (2005) (0)
Crystal structure of the phosphoribosylpyrophosphate (PRPP) synthetase from Thermoplasma volcanium in complex with an ATP analog (AMPCPP). (2011) (0)
Crystal structure of Bovine prion protein complexed with POM1 FAB (2015) (0)
Protein Structure and Biology (2013) (0)
X-ray crystal structure of RV0760c from Mycobacterium tuberculosis at 1.82 Angstrom resolution (2007) (0)
Crystal structure of human alpha-L-iduronidase in the P212121 form (2015) (0)
A stereochemical analysis of the aspartyl proteinase hydrolytic mechanism (1984) (0)
X-ray crystal structure of mycobacterium tuberculosis pyridoxine 5'-phosphate oxidase complexed with pyridoxal 5'-phosphate at 1.7 a resolution (2005) (0)
The Crystal Structure of Ornithine Acetyltransferase from Mycobacterium tuberculosis (Rv1653) at 1.7 A (2010) (0)
Crystal structure of sulfide:quinone oxidoreductase Cys128Ser variant from Acidithiobacillus ferrooxidans in complex with decylubiquinone (2012) (0)
Crystal structure of the oligomerization domain hexamer of the arginine repressor protein from Mycobacterium tuberculosis in complex with 9 arginines. (2008) (0)
X-ray crystal structure of Protein Phosphatase-1 with the marine toxin motuporin bound (2006) (0)
X-ray crystal structure of RV0760c from Mycobacterium tuberculosis in complex with estradiol-17beta-hemisuccinate (2007) (0)
Crystal structure of sulfide:quinone oxidoreductase from Acidithiobacillus ferrooxidans, C160A mutant (2010) (0)
THE MOLECULAR AND CRYSTAL STRUCTURES OF MONOCLINIC PORCINE PEPSIN REFINED AT 1.8 ANGSTROMS RESOLUTION (1990) (0)
Crystal structure of the N-terminally truncated OMTKY3-del(1-5) (2007) (0)
Crystal structure of sulfide:quinone oxidoreductase H198A variant from Acidithiobacillus ferrooxidans in complex with bound trisulfide and decylubiquinone (2012) (0)
Crystal structure of sulfide:quinone oxidoreductase from Acidithiobacillus ferrooxidans in complex with sodium selenide (2012) (0)
Crystallization and preliminary X‐ray diffraction studies of two mutants of lactate dehydrogenase from Bacillus stearothermophilus (1992) (0)
Bovine beta-trypsin bound to meta-diguanidino schiff base copper (II) chelate (2001) (0)
CRYSTAL STRUCTURE OF THE OMTKY3 P1 VARIANT OMTKY3-ILE18I IN COMPLEX WITH SGPB (2000) (0)
X-ray crystal structure of NGT-bound HexA (2006) (0)
Rationalization of inhibitor binding in serine/threonine phosphatases (2002) (0)
Crystal Structure of Haloalkane Dehalogenase Rv2579 from Mycobacterium tuberculosis (2008) (0)
CRYSTAL STRUCTURE OF OMTKY3-CH2-ASP19I (2001) (0)
Crystal structure ofa flavoprotein related tothe subunits ofbacterial luciferase (1993) (0)
Streptomyces plicatus beta-N-acetylhexosaminidase in Complex with (2R,3R,4S,5R)-2-acetamido-3,4-dihydroxy-5-hydroxymethyl-piperidinium chloride (IFG) (2001) (0)
Crystal structures of SARS coronavirus main peptidase inhibited by an aza-peptide epoxide in space group P212121 (2005) (0)
The importance of refined structures to the understanding of enzyme function (1981) (0)
Crystal structure of haloalkane dehalogenase Rv2579 from Mycobacterium tuberculosis complexed with 1,2-dichloroethane (2007) (0)
Crystallographic Analyses of Peptide Inhibitors of Aspartic Proteinases (1991) (0)
The structure-based design of three potent inhibitors of TEM-1 β-lactamase (1996) (0)
X-ray crystal structure of hepatitis C virus RNA dependent RNA polymerase in complex with non-nucleoside analogue inhibitor (2006) (0)
GLY 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B (1995) (0)
Crystal structure of tomato inhibitor-II in a ternary complex with subtilisin Carlsberg (2003) (0)
ACTIVATION INTERMEDIATE 2 OF HUMAN GASTRICSIN FROM HUMAN STOMACH (1998) (0)
Crystal structures of the Glu18, Gln18, Asp18 and Asn18 variants of turkey ovomucoid inhibitor third domain complexed with Streptomyces griseus proteinase B at various pHs (1996) (0)
Crystal structure of sulfide:quinone oxidoreductase from Acidithiobacillus ferrooxidans in complex with decylubiquinone (2010) (0)
ALA 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B (1995) (0)
The structure of N‐(3‐bromo‐1‐methyl‐2‐piperidylidene)benzenesulfonamide (1987) (0)
Structure of SCP-B a member of the Eqolisin family of Peptidases in a complex with a Tripeptide Ala-Ile-His (2004) (0)
Crystal structure of LL-diaminopimelate aminotransferase from Arabidopsis thaliana complexed with PLP-DAP: an external aldimine mimic (2008) (0)
LEU 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B (1995) (0)
Crystal structure of sulfide:quinone oxidoreductase from Acidithiobacillus ferrooxidans with bound trisulfide and decylubiquinone (2012) (0)
Reaction pathway of aspartic proteinases supported by substrate analogue binding to penicillopepsin (1987) (0)
Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I (2006) (0)
Structure of 5-[(1S,2S)-2-chlorocyclopropyl]-1-(2-deoxy-β-d-ribofuranosyl)uracil (1990) (0)
A proposal for a substrate-assisted catalytic mechanism for serine peptidases (2018) (0)
The Structure of the Intermediate Complex of the Arginine Repressor from Mycobacterium tuberculosis Bound to its DNA Operator and L-canavanine. (2010) (0)
Crystal structure of the conserved hypothetical protein Rv1873 from Mycobacterium tuberculosis at 1.58 A (2005) (0)
Crystal structure of the SGPB:P14'-Ala32 OMTKY3-del(1-5) complex (2007) (0)
The 4.5 Angstrom resolution structure of a bacterial serine protease from Streptomyces griseus. (1974) (0)
Crystal structure of scytalido-glutamic peptidase with a transition state analog inhibitor (2006) (0)
Crystal structure of PLP-bound LL-diaminopimelate aminotransferase from Chlamydia trachomatis (2011) (0)
STRUCTURE AND REFINEMENT OF PENICILLOPEPSIN AT 1.8 ANGSTROMS RESOLUTION (1983) (0)
Crystal structure of probable thiosulfate sulfurtransferase CYSA3 (RV3117) from Mycobacterium tuberculosis: orthorhombic form (2009) (0)
BOVINE BETA-TRYPSIN BOUND TO META-AMIDINO SCHIFF BASE MAGNESIUM(II) CHELATE (2001) (0)
Crystal structure of the P14'-Ala32 variant of the N-terminally truncated OMTKY3-del(1-5) (2007) (0)
ACID PROTEINASE (PENICILLOPEPSIN) (E.C.3.4.23.20) COMPLEX WITH PHOSPHONATE MACROCYCLIC INHIBITOR:METHYL[CYCLO-7[(2R)-((N-VALYL)AMINO)-2-(HYDROXYL-(1S)-1-METHYOXYCARBONYL-2-PHENYLETHOXY)PHOSPHINYLOXY-ETHYL]-1-NAPHTHALENEACETAMIDE], SODIUM SALT (1998) (0)
Consequences of intramolecular ionic interactions for the activation rate of human pepsinogens A and C as revealed by molecular modelling. (1991) (0)
NSP4 proteinase from Equine Arteritis Virus (2002) (0)
Crystal structure of the cathepsin K : chondroitin sulfate complex. (2008) (0)
Wildtype Streptomyces plicatus beta-hexosaminidase in complex with product (GlcNAc) (2003) (0)
Crystal structure of human alpha-L-iduronidase complex with 2-deoxy-2-fluoro-alpha-L-idopyranosyluronic acid fluoride (2013) (0)
Crystallization of human beta-hexosaminidase B. (1992) (0)
Crystal structure of the phosphoribosyl pyrophosphate (PRPP) synthetase from Thermoplasma volcanium in complex with ADP. (2011) (0)
Mechanism of stereospecific substrate recognition by LL-diaminopimelate aminotransferase (2008) (0)
Protein–protein recognition: the interfaces of protein inhibitors and the serine proteinases (1987) (0)
Crystal structure of the conserved hypothetical protein Rv2074 from Mycobacterium tuberculosis 1.6 A (2005) (0)
2A CYSTEINE PROTEINASE FROM HUMAN RHINOVIRUS 2 (2000) (0)
ACID PROTEINASE (PENICILLOPEPSIN) (E.C.3.4.23.20) COMPLEX WITH PHOSPHONATE MACROCYCLIC INHIBITOR: METHYL[CYCLO-7[(2R)-((N-VALYL)AMINO)-2-(HYDROXYL-(1S)-1-METHYOXYCARBONYL-2-PHENYLETHOXY) PHOSPHINYLOXY-ETHYL]-1-NAPHTHALENEACETAMIDE] SODIUM SALT (1998) (0)
Crystal structure of haloalkane dehalogenase Rv2579 from Mycobacterium tuberculosis complexed with 1,3-propandiol (2007) (0)
Crystal structure of a Protein Phosphatase-1: Calcineurin Hybrid Bound to Okadaic Acid (2004) (0)
PHE 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B (2003) (0)
Crystal structure of the conserved hypothetical protein Rv1873 from Mycobacterium tuberculosis at 1.38 A (2007) (0)
Crystal structure of human alpha-L-iduronidase complex with alpha-L-iduronic acid (2015) (0)
Structure of Rv0793 from Mycobacterium tuberculosis (2004) (0)
ASN 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B (2003) (0)
Crystal structure of unbound SARS coronavirus main peptidase in the space group C2 (2005) (0)
Regulatory RNA elements. Preface. (2009) (0)
Crystal structure of SARS coronavirus main peptidase at pH 6.0 in the space group P21 (2006) (0)
Molecular mechanisms underlying the interaction of protein phosphatase-1 c with ASPP proteins (2012) (0)
Biochemical and structural assessment of the 1-N-azasugar GalNAc-isofagomine as a potent family 20 β-hexosaminidase inhibitor (2002) (0)
Crystal structure of the second tetrahedral intermediates of SGPB at pH 7.3 (2007) (0)
Crystal structure of human alpha-L-iduronidase, rhombohedral form (2013) (0)
Genetic algorithms and macromolecular phasing (1996) (0)
Progress in the refinement of the structure of α-lytic protease at 1.8 Å resolution (1981) (0)
THE MOLECULAR CONFORMATION OF 1E,2A,6E-TRIMETHYL-4E-PHENYL-4A-ACETOXYPIPERIDINE HYDROBROMIDE IN THE CRYSTALLINE STATE (1973) (0)
Crystal structure of the phosphoribosylpyrophosphate (PRPP) synthetase from Thermoplasma volcanium in complex with ADP-Mg2+ and ribose 5-phosphate (2011) (0)
Contribution of crystallography to the elucidation of hydrolytic enzyme mechanisms (1993) (0)
Crystallographic studies of an activation intermediate of human gastricsin. (1998) (0)
Hepatitis C Virus RNA Polymerase Genotype 2a In Complex With Non- Nucleoside Analogue Inhibitor (2005) (0)
Crystal structure of K270N variant of LL-diaminopimelate aminotransferase from Arabidopsis thaliana (2008) (0)
Mutant Streptomyces plicatus beta-hexosaminidase (D313A) in complex with product (GlcNAc) (2002) (0)
The Crystal Structure of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside Deacetylase (MshB) (2003) (0)
X-RAY CRYSTALLOGRAPHIC STUDY OF CALCIUM-SATURATED N-TERMINAL DOMAIN OF TROPONIN C (1997) (0)
Crystal structure of diaminopimelate epimerase form arabidopsis thaliana in complex with irreversible inhibitor DL-AziDAP (2009) (0)
Crystal structure of diaminopimelate epimerase in complex with an irreversible inhibitor DL-AZIDAP (2006) (0)
Structure of POM6 FAB fragment complexed with mouse PrPc (2018) (0)
X-ray Crystal Structure of RV0760 from Mycobacterium Tuberculosis at 1.68 Angstrom Resolution (2005) (0)
Crystal structure of beta subunit of acyl-CoA carboxylase AccD1 from Mycobacterium tuberculosis (2016) (0)
THE REFINED 1.7 ANGSTROMS X-RAY CRYSTALLOGRAPHIC STRUCTURE OF P-30, AN AMPHIBIAN RIBONUCLEASE WITH ANTI-TUMOR ACTIVITY (1994) (0)
Human pepsin 3A in complex with a phosphonate inhibitor IVA-VAL-VAL-LEU(P)-(O)PHE-ALA-ALA-OME (1999) (0)
Crystal structure of human alpha-L-iduronidase, monoclinic form (2013) (0)
Structures of SARS coronavirus main protease bound by an Aza-peptide epoxide (2005) (0)
Expression, purification, crystallization and preliminary crystallographic analysis of the phosphoglycerate kinase from Acinetobacter baumannii. (2012) (0)
CRYSTAL STRUCTURE OF ASCARIS PEPSIN INHIBITOR-3 BOUND TO PORCINE PEPSIN (2001) (0)
A comparative molecular model of the Ca2+sensitive regulatory protein calmodulin based on turkey skeletal troponin-C (1987) (0)

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Kyoto Institute of Technology
University of Alberta
Kumamoto University

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