Michael N. Hall | Academic Influence

Michael N. Hall's AcademicInfluence.com Rankings

Michael N. Hall

Biology

#1069

World Rank

#1840

Historical Rank

#559

USA Rank

Molecular Biology

#164

World Rank

#168

Historical Rank

#84

USA Rank

biology Degrees

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Biology

Michael N. Hall's Degrees

PhD Biochemistry University of Basel

Why Is Michael N. Hall Influential?

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According to Wikipedia, Michael Nip Hall is an American-Swiss molecular biologist and professor at the Biozentrum of the University of Basel, Switzerland. He discovered TOR, a protein central for regulating cell growth. Early life and education Hall was born in Puerto Rico. His parents liked Latin American culture, so they moved to Peru when he was three years old, and then to Venezuela a few years later. When Hall was 13, he went to the United States for boarding school, at St. Mark's School in Southborough, Massachusetts.

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Michael N. Hall's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

TOR Signaling in Growth and Metabolism (2006) (5669)
Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive (2004) (2094)
TOR, a Central Controller of Cell Growth (2000) (2005)
Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. (2002) (1794)
The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors (1999) (976)
Making new contacts: the mTOR network in metabolism and signalling crosstalk (2014) (918)
Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression (1993) (843)
Rapamycin passes the torch: a new generation of mTOR inhibitors (2011) (836)
Target of Rapamycin (TOR) in Nutrient Signaling and Growth Control (2011) (778)
Sch9 is a major target of TORC1 in Saccharomyces cerevisiae. (2007) (768)
TOR controls translation initiation and early G1 progression in yeast. (1996) (749)
Activation of mTORC2 by Association with the Ribosome (2011) (641)
Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy. (2008) (620)
Glutaminolysis activates Rag-mTORC1 signaling. (2012) (569)
TOR signalling in bugs, brain and brawn (2003) (563)
mTOR signalling and cellular metabolism are mutual determinants in cancer (2018) (522)
The expanding TOR signaling network. (2005) (522)
TOR signalling and control of cell growth. (1997) (514)
Nuclear protein localization. (1991) (510)
Nutrient sensing and TOR signaling in yeast and mammals (2017) (488)
Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c. (2012) (477)
Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration. (2008) (473)
TOR Regulates Ribosomal Protein Gene Expression via PKA and the Forkhead Transcription Factor FHL1 (2004) (466)
Where is mTOR and what is it doing there? (2013) (463)
mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice. (2011) (461)
Signaling to the actin cytoskeleton. (1998) (454)
Role of mTOR in podocyte function and diabetic nephropathy in humans and mice. (2011) (453)
Quantitative Phosphoproteomics Reveal mTORC1 Activates de Novo Pyrimidine Synthesis (2013) (442)
mTOR signaling in disease. (2011) (430)
mTOR in aging, metabolism, and cancer. (2013) (425)
TOR1 and TOR2 are structurally and functionally similar but not identical phosphatidylinositol kinase homologues in yeast. (1994) (392)
mTOR complex 2-Akt signaling at mitochondria-associated endoplasmic reticulum membranes (MAM) regulates mitochondrial physiology (2013) (377)
Elucidating TOR Signaling and Rapamycin Action: Lessons from Saccharomyces cerevisiae (2002) (367)
The TOR-controlled transcription activators GLN3, RTG1, and RTG3 are regulated in response to intracellular levels of glutamine (2002) (352)
The TOR nutrient signalling pathway phosphorylates NPR1 and inhibits turnover of the tryptophan permease (1998) (334)
The Yeast Phosphatidylinositol Kinase Homolog TOR2 Activates RHO1 and RHO2 via the Exchange Factor ROM2 (1997) (328)
Targeting of E. coli β-galactosidase to the nucleus in yeast (1984) (308)
Starvation Induces Vacuolar Targeting and Degradation of the Tryptophan Permease in Yeast (1999) (305)
mTOR and the control of whole body metabolism. (2009) (301)
Cell Wall Stress Depolarizes Cell Growth via Hyperactivation of Rho1 (1999) (298)
Genetic analysis of protein export in Escherichia coli K12. (1985) (297)
PRAS40 and PRR5-Like Protein Are New mTOR Interactors that Regulate Apoptosis (2007) (297)
The ompB locus and the regulation of the major outer membrane porin proteins of Escherichia coli K12. (1981) (297)
The Search for Antiaging Interventions: From Elixirs to Fasting Regimens (2014) (293)
AMPK and TOR: The Yin and Yang of Cellular Nutrient Sensing and Growth Control. (2020) (289)
Bidirectional crosstalk between endoplasmic reticulum stress and mTOR signaling. (2012) (289)
A role for mRNA secondary structure in the control of translation initiation (1982) (288)
Inhibition of mTOR with sirolimus slows disease progression in Han:SPRD rats with autosomal dominant polycystic kidney disease (ADPKD). (2006) (287)
TOR complex 2: a signaling pathway of its own. (2009) (287)
TOR2 is required for organization of the actin cytoskeleton in yeast. (1996) (279)
FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae. (1991) (272)
Genetic analysis of the ompB locus in Escherichia coli K-12. (1981) (263)
Activation of the RAS/Cyclic AMP Pathway Suppresses a TOR Deficiency in Yeast (2004) (262)
Cyclosporin A, FK506 and rapamycin: more than just immunosuppression. (1993) (261)
mTORC1 mediated translational elongation limits intestinal tumour initiation and growth (2014) (258)
Architecture of human mTOR complex 1 (2016) (258)
mTOR signaling in cellular and organismal energetics. (2015) (252)
Insulin resistance causes inflammation in adipose tissue (2018) (244)
Molecular Organization of Target of Rapamycin Complex 2* (2005) (239)
The Rapamycin-sensitive Phosphoproteome Reveals That TOR Controls Protein Kinase A Toward Some But Not All Substrates (2010) (236)
mTORC2 Promotes Tumorigenesis via Lipid Synthesis. (2017) (235)
TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway. (2001) (229)
Tor2 Directly Phosphorylates the AGC Kinase Ypk2 To Regulate Actin Polarization (2005) (228)
AKT Promotes rRNA Synthesis and Cooperates with c-MYC to Stimulate Ribosome Biogenesis in Cancer (2011) (220)
Cardiac Raptor Ablation Impairs Adaptive Hypertrophy, Alters Metabolic Gene Expression, and Causes Heart Failure in Mice (2011) (216)
Growth and aging: a common molecular mechanism (2009) (214)
MSS4, a Phosphatidylinositol-4-phosphate 5-Kinase Required for Organization of the Actin Cytoskeleton in Saccharomyces cerevisiae * (1998) (210)
Inhibition of mTORC1 by Astrin and Stress Granules Prevents Apoptosis in Cancer Cells (2013) (204)
The stress-activated phosphatidylinositol 3-phosphate 5-kinase Fab1p is essential for vacuole function in S. cerevisiae (1998) (203)
TOR2 is part of two related signaling pathways coordinating cell growth in Saccharomyces cerevisiae. (1998) (193)
Cell wall integrity modulates RHO1 activity via the exchange factor ROM2 (1998) (190)
Sphingoid base signaling via Pkh kinases is required for endocytosis in yeast (2001) (186)
mTOR complex 2 in adipose tissue negatively controls whole-body growth (2009) (176)
Dual Inhibition of the Lactate Transporters MCT1 and MCT4 Is Synthetic Lethal with Metformin due to NAD+ Depletion in Cancer Cells (2018) (175)
Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease (2008) (169)
The Rho1 effector Pkc1, but not Bni1, mediates signalling from Tor2 to the actin cytoskeleton (1998) (167)
mTOR-what does it do? (2008) (167)
Two FK506 resistance-conferring genes in Saccharomyces cerevisiae, TAT1 and TAT2, encode amino acid permeases mediating tyrosine and tryptophan uptake. (1994) (164)
Multiple amino acid sensing inputs to mTORC1 (2015) (161)
HEAT Repeats Mediate Plasma Membrane Localization of Tor2p in Yeast* (2000) (156)
TOR1 and TOR2 Have Distinct Locations in Live Cells (2008) (152)
PDK1 Homologs Activate the Pkc1–Mitogen-Activated Protein Kinase Pathway in Yeast (1999) (149)
Yeast Protein Kinases and the RHO1 Exchange Factor TUS1 Are Novel Components of the Cell Integrity Pathway in Yeast (2002) (145)
Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition. (2014) (143)
mTORC1 Directly Phosphorylates and Regulates Human MAF1 (2010) (143)
The T-DNA-linked VirD2 protein contains two distinct functional nuclear localization signals. (1992) (143)
Genome‐wide lethality screen identifies new PI4,5P2 effectors that regulate the actin cytoskeleton (2004) (141)
Genetic analysis of the major outer membrane proteins of Escherichia coli. (1981) (140)
Nitrogen Source Activates TOR (Target of Rapamycin) Complex 1 via Glutamine and Independently of Gtr/Rag Proteins* (2014) (140)
The Solution Structure of the FATC Domain of the Protein Kinase Target of Rapamycin Suggests a Role for Redox-dependent Structural and Cellular Stability* (2005) (138)
Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21 (2014) (136)
Transcriptional regulation of Escherichia coli K-12 major outer membrane protein 1b (1979) (135)
Hypoxia-Induced Endothelial Proliferation Requires Both mTORC1 and mTORC2 (2007) (135)
Eap1p, a Novel Eukaryotic Translation Initiation Factor 4E-Associated Protein in Saccharomyces cerevisiae (2000) (133)
Cell growth : control of cell size (2004) (132)
Balanced mTORC1 Activity in Oligodendrocytes Is Required for Accurate CNS Myelination (2014) (131)
The protein histidine phosphatase LHPP is a tumour suppressor (2018) (125)
Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy (2013) (124)
PIK1, an essential phosphatidylinositol 4‐kinase associated with the yeast nucleus. (1994) (119)
WNT7B Promotes Bone Formation in part through mTORC1 (2014) (118)
HIF-independent role of prolyl hydroxylases in the cellular response to amino acids (2012) (117)
TOR signaling in invertebrates. (2009) (113)
Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice. (2015) (111)
The TSC-mTOR Pathway Mediates Translational Activation of TOP mRNAs by Insulin Largely in a Raptor- or Rictor-Independent Manner (2008) (107)
Quantitation of changes in protein phosphorylation: A simple method based on stable isotope labeling and mass spectrometry (2003) (106)
The opposing actions of target of rapamycin and AMP-activated protein kinase in cell growth control. (2015) (105)
Proline isomerases at the crossroads of protein folding, signal transduction, and immunosuppression. (1992) (105)
The GATA Transcription Factors GLN3 and GAT1 Link TOR to Salt Stress in Saccharomyces cerevisiae * (2001) (104)
Sch 9 Is a Major Target of TORC 1 in Saccharomyces cerevisiae (104)
mTORC2 sustains thermogenesis via Akt‐induced glucose uptake and glycolysis in brown adipose tissue (2016) (103)
Homeo domain of the yeast repressor alpha 2 is a sequence-specific DNA-binding domain but is not sufficient for repression. (1987) (102)
A mechanism of protein localization: the signal hypothesis and bacteria (1980) (102)
Regulation of TOR by small GTPases (2012) (100)
Mitochondria‐Endoplasmic Reticulum Contact Sites Function as Immunometabolic Hubs that Orchestrate the Rapid Recall Response of Memory CD8+ T Cells (2018) (100)
Network-based integration of multi-omics data for prioritizing cancer genes (2018) (99)
Loss of mTORC1 signalling impairs β-cell homeostasis and insulin processing (2017) (99)
mTORC1 controls PNS myelination along the mTORC1-RXRγ-SREBP-lipid biosynthesis axis in Schwann cells. (2014) (98)
TORC1-regulated protein kinase Npr1 phosphorylates Orm to stimulate complex sphingolipid synthesis (2013) (95)
Mammalian Target of Rapamycin Complex 2 Controls CD8 T Cell Memory Differentiation in a Foxo1-Dependent Manner. (2016) (95)
The immunosuppressant FK506 inhibits amino acid import in Saccharomyces cerevisiae (1993) (91)
The Early days of yeast genetics (1993) (90)
mTORC1 Plays an Important Role in Skeletal Development by Controlling Preosteoblast Differentiation (2017) (87)
Mutual Antagonism of Target of Rapamycin and Calcineurin Signaling* (2006) (82)
Brief Report: The Differential Roles of mTORC1 and mTORC2 in Mesenchymal Stem Cell Differentiation (2015) (80)
mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress (2014) (76)
Homeodomain of yeast repressor alpha 2 contains a nuclear localization signal. (1990) (75)
Third target of rapamycin complex negatively regulates development of quiescence in Trypanosoma brucei (2012) (75)
TORC1 Promotes Phosphorylation of Ribosomal Protein S6 via the AGC Kinase Ypk3 in Saccharomyces cerevisiae (2015) (72)
Inhibition of mTORC 1 by Astrin and Stress Granules Prevents Apoptosis in Cancer Cells (2013) (71)
Sequence information within the lamB genes in required for proper routing of the bacteriophage lambda receptor protein to the outer membrane of Escherichia coli K-12. (1982) (71)
Regulation of mTORC2 Signaling (2020) (71)
Activation of mTORC 2 by Association with the Ribosome (2011) (67)
Mammalian Target of Rapamycin Complex 1 Orchestrates Invariant NKT Cell Differentiation and Effector Function (2014) (66)
Zim17, a Novel Zinc Finger Protein Essential for Protein Import into Mitochondria* (2004) (65)
Combined inhibition of PI3K-related DNA damage response kinases and mTORC1 induces apoptosis in MYC-driven B-cell lymphomas. (2013) (65)
TOR: the first 10 years. (2004) (64)
Glutaminolysis feeds mTORC1 (2012) (62)
mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation (2016) (62)
mTOR Signaling Confers Resistance to Targeted Cancer Drugs. (2016) (62)
TOR regulates late steps of ribosome maturation in the nucleoplasm via Nog1 in response to nutrients (2006) (62)
A yeast cyclophilin gene essential for lactate metabolism at high temperature. (1992) (61)
Quantitative proteomics and phosphoproteomics on serial tumor biopsies from a sorafenib-treated HCC patient (2016) (56)
The TOR signalling pathway and growth control in yeast. (1996) (56)
Identification of OmpR: a positive regulatory protein controlling expression of the major outer membrane matrix porin proteins of Escherichia coli K-12 (1981) (55)
mTOR in health and in sickness (2015) (55)
mTORC2 Caught in a SINful Akt. (2006) (55)
mTORC2 Signaling Drives the Development and Progression of Pancreatic Cancer. (2016) (55)
An Amino Acid Shuffle Activates mTORC1 (2009) (54)
Regulation of ribosome biogenesis: where is TOR? (2006) (53)
NPR1 Kinase and RSP5-BUL1/2 Ubiquitin Ligase Control GLN3-dependent Transcription in Saccharomyces cerevisiae* (2004) (53)
CLIP and cohibin separate rDNA from nucleolar proteins destined for degradation by nucleophagy (2018) (53)
SnapShot: mTOR Signaling (2007) (53)
Architecture of the human mTORC2 core complex (2018) (52)
CLN3 expression is sufficient to restore G1-to-S-phase progression in Saccharomyces cerevisiae mutants defective in translation initiation factor eIF4E. (1999) (51)
Cardiac mTOR complex 2 preserves ventricular function in pressure-overload hypertrophy. (2016) (49)
Calmodulin controls organization of the actin cytoskeleton via regulation of phosphatidylinositol (4,5)-bisphosphate synthesis in Saccharomyces cerevisiae. (2002) (48)
Isolation and characterization of mutations altering expression of the major outer membrane porin proteins using the local anaesthetic procaine. (1983) (47)
Genome-wide shRNA screen reveals increased mitochondrial dependence upon mTORC2 addiction (2011) (44)
The 3.2-Å resolution structure of human mTORC2 (2020) (42)
Impact papers on aging in 2009 (2010) (40)
Inducible raptor and rictor knockout mouse embryonic fibroblasts. (2012) (38)
Activating Mutations in TOR Are in Similar Structures As Oncogenic Mutations in PI3KCα (2009) (38)
Identification of immunosuppressive drug targets in yeast (1993) (38)
Rictor in Perivascular Adipose Tissue Controls Vascular Function by Regulating Inflammatory Molecule Expression (2013) (36)
mTOR substrate phosphorylation in growth control (2022) (36)
Syrosingopine sensitizes cancer cells to killing by metformin (2016) (36)
Rank Difference Analysis of Microarrays (RDAM), a novel approach to statistical analysis of microarray expression profiling data (2004) (36)
Loss of mTORC1 signaling alters pancreatic &agr; cell mass and impairs glucagon secretion (2017) (35)
Targeting of E. coli beta-galactosidase to the nucleus in yeast. (1984) (35)
The TSC-mTOR Pathway Mediates Translational Activation of TOP mRNAs by Insulin Largely in a Raptor- or Rictor-Independent Manner (2009) (34)
mTORC 1 Controls PNS Myelination along the mTORC 1-RXR gamma-SREBP-Lipid Biosynthesis Axis in Schwann Cells (33)
TOR signalling in bugs, brain and brawn (2003) (32)
mTORC2 critically regulates renal potassium handling. (2016) (31)
Transport of proteins into the nucleus (1988) (31)
Inferring causal metabolic signals that regulate the dynamic TORC1-dependent transcriptome (2015) (31)
Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase. (2008) (30)
LATS1 but not LATS2 represses autophagy by a kinase-independent scaffold function (2019) (29)
Proximity Ligation Assay for High-content Profiling of Cell Signaling Pathways on a Microfluidic Chip* (2013) (26)
NGS-pipe: a flexible, easily extendable and highly configurable framework for NGS analysis (2017) (26)
Loss of mTOR signaling affects cone function, cone structure and expression of cone specific proteins without affecting cone survival. (2015) (26)
Target of rapamycin (TOR) kinase in Trypanosoma brucei: an extended family. (2013) (25)
Conditional disruption of rictor demonstrates a direct requirement for mTORC2 in skin tumor development and continued growth of established tumors. (2015) (24)
mTORC1: Turning Off Is Just as Important as Turning On (2014) (24)
Inhibition of mTORC1 by Astrin and Stress Granules Prevents Apoptosis in Cancer Cells (2013) (23)
FAP1, a homologue of human transcription factor NF‐X1, competes with rapamycin for binding to FKBP12 in yeast (2000) (22)
TOR : target of rapamycin (2004) (22)
Negative Regulation of Phosphatidylinositol 4,5-Bisphosphate Levels by the INP51-associated Proteins TAX4 and IRS4* (2004) (22)
Leucyl-tRNA synthetase: double duty in amino acid sensing (2012) (21)
Talks about TORCs: recent advancesin target of rapamycin signalling. On mTOR nomenclature. (2013) (21)
USP29-mediated HIF1α stabilization is associated with Sorafenib resistance of hepatocellular carcinoma cells by upregulating glycolysis (2021) (21)
Expression of the Bacterial Type III Effector DspA/E in Saccharomyces cerevisiae Down-regulates the Sphingolipid Biosynthetic Pathway Leading to Growth Arrest* (2014) (20)
Mammalian Target of Rapamycin Complex 2 Modulates αβTCR Processing and Surface Expression during Thymocyte Development (2014) (20)
WNT 7 B promotes bone formation in part through mTORC 1 (2015) (19)
Analysis of deletion phenotypes and GFP fusions of 21 novel Saccharomyces cerevisiae open reading frames (2000) (19)
The dynamic mechanism of 4E-BP1 recognition and phosphorylation by mTORC1. (2021) (19)
Active transport of proteins into the nucleus (1990) (19)
TOR signaling in yeast : temporal and spatial control of cell growth (2004) (18)
Proteomic Landscape of Aldosterone-Producing Adenoma (2019) (18)
Signal transduction: Linking nutrients to growth (2008) (17)
PAS Kinase Promotes Cell Survival and Growth Through Activation of Rho1 (2012) (17)
Epidermal mTORC2 controls lipid synthesis and filaggrin processing in epidermal barrier formation. (2019) (17)
TOR and paradigm change: cell growth is controlled (2016) (17)
Endothelial Rictor is crucial for midgestational development and sustained and extensive FGF2-induced neovascularization in the adult (2015) (17)
mTORC1 signaling in Agrp neurons mediates circadian expression of Agrp and NPY but is dispensable for regulation of feeding behavior. (2015) (17)
Shared Molecular Targets Confer Resistance over Short and Long Evolutionary Timescales. (2019) (16)
Selective ATP-competitive inhibitors of TOR suppress rapamycin-insensitive function of TORC2 in Saccharomyces cerevisiae. (2012) (16)
Maximizing the Efficacy of MAPK-Targeted Treatment in PTENLOF/BRAFMUT Melanoma through PI3K and IGF1R Inhibition. (2016) (16)
TSC on the peroxisome controls mTORC1 (2013) (16)
Yeast cell-free nuclear protein import requires ATP hydrolysis. (1991) (16)
mTORC1 plays an important role in osteoblastic regulation of B-lymphopoiesis (2018) (15)
Indirect monitoring of TORC1 signalling pathway reveals molecular diversity among different yeast strains (2018) (12)
TOR signaling and control of cell growth (2007) (12)
Nuclear protein transport is functionally conserved between yeast and higher eukaryotes (1993) (12)
An Amazing Turn of Events (2017) (11)
Impact papers on aging in 2009 - eScholarship (2010) (11)
Raptor ablation in skeletal muscle decreases Cav1.1 expression and affects the function of the excitation-contraction coupling supramolecular complex. (2015) (11)
Conserved sequence motifs and the structure of the mTOR kinase domain. (2013) (11)
Deletion of Rictor in Brain and Fat Alters Peripheral Clock Gene Expression and Increases Blood Pressure (2015) (11)
Nuclear import substrates compete for a limited number of binding sites. Evidence for different classes of yeast nuclear import receptors. (1991) (11)
Genetic studies on mechanisms of protein localization in Escherichia coli K-12. (1980) (10)
Talks About TORCs: Recent Advances in Target of Rapamycin Signalling (2013) (10)
Integrative proteogenomic characterization of hepatocellular carcinoma across etiologies and stages (2022) (10)
Holding back TOR advances mitosis (2007) (10)
Evolution of TOR and Translation Control (2016) (10)
Landmark papers in yeast biology (2006) (9)
Reconsidering the early steps of protein secretion. (1982) (9)
Control of the actin cytoskeleton by extracellular signals. (2001) (9)
Signal sequence mutations that alter coupling of secretion and translation of an Escherichia coli outer membrane protein (1987) (9)
Regional bivalent-univalent pairing versus trivalent pairing of a trisomic chromosome in Saccharomyces cerevisiae. (1996) (9)
mTORC 2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue (2016) (9)
Nuclear protein localization signals in yeast (1986) (8)
Architecture of the human mTORC 2 core complex (2018) (8)
Structure, function and regulation of TOR complexes from yeasts to mammals (2010) (8)
Translational control by amino acids and energy (2009) (8)
Leucyl-tRNA synthetase: double duty in amino acid sensing (2012) (8)
mTOR signaling mediates ILC3-driven immunopathology (2021) (7)
A reference map of sphingolipids in murine tissues. (2021) (7)
KAE1 Allelic Variants Affect TORC1 Activation and Fermentation Kinetics in Saccharomyces cerevisiae (2019) (7)
TOR complexes : composition, structure and phosphorylation (2010) (7)
Faculty Opinions recommendation of Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis. (2005) (6)
Multi-omics data integration reveals novel drug targets in hepatocellular carcinoma (2021) (6)
Loss of TSC complex enhances gluconeogenesis via upregulation of Dlk1-Dio3 locus miRNAs (2020) (6)
Evaluation of the expanded Southampton pilot study (Phase 2) for use of saliva-based lamp testing in asymptomatic populations: Final report, 16th November 2020 (2020) (5)
Adipose mTORC2 is essential for sensory innervation in white adipose tissue and whole-body energy homeostasis (2022) (5)
mTORC1 Controls Synthesis of Its Activator GTP. (2017) (4)
Reduced C/EBPβ‐LIP translation improves metabolic health (2015) (4)
Correction: TOR signalling in bugs, brain and brawn (2003) (4)
Regulation of human mTOR complexes by DEPTOR (2021) (4)
Basal mTORC2 activity and expression of its components display diurnal variation in mouse perivascular adipose tissue. (2016) (4)
Treatment of Primary Aldosteronism with mTORC1 Inhibitors. (2019) (4)
The solution structure of the FATC Domain of the Protein Kinase TOR1 from yeast (2005) (3)
cerevisiae Saccharomyces Action : Lessons from Elucidating TOR Signaling and Rapamycin (2002) (3)
Basal m diurnal variation in mouse perivascular adipose tissue TORC2 activity and expression of its components display (2016) (3)
Faculty Opinions recommendation of Akt deficiency impairs normal cell proliferation and suppresses oncogenesis in a p53-independent and mTORC1-dependent manner. (2007) (3)
A population of innate myelolymphoblastoid effector cell expanded by inactivation of mTOR complex 1 in mice (2017) (3)
mTORC1 and mTORC2 in energy homeostasis (2010) (3)
Two FK506 resistance-conferring genes in Saccharomyces cerevisiae, TAT1 and TAT2, encode amino acid permeases mediating tyrosine and tryptophan uptake (1994) (2)
Mechanism of T-DNA Transfer (1993) (2)
Transcription factors TEAD2 and E2A globally repress acetyl-CoA synthesis to promote tumorigenesis. (2022) (2)
Faculty Opinions recommendation of Extension of chronological life span in yeast by decreased TOR pathway signaling. (2006) (2)
Genetic approaches to study export of LamB to the outer membrane. (1982) (2)
Multi-omics subtyping of hepatocellular carcinoma patients using a Bayesian network mixture model (2021) (2)
Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy (2013) (2)
TORC1 phosphorylates and inhibits the ribosome preservation factor Stm1 to activate dormant ribosomes (2022) (2)
Proteogenomic characterization of hepatocellular carcinoma (2021) (2)
mTORC1 induces apoptosis in MYC-driven B-cell lymphomas Combined inhibition of PI3K-related DNA damage response kinases and (2013) (2)
An Isogenic Cell Panel Identifies Compounds That Inhibit Proliferation of mTOR-Pathway Addicted Cells by Different Mechanisms (2014) (1)
Diet-induced loss of adipose Hexokinase 2 triggers hyperglycemia (2019) (1)
Lactate jump‐starts mTORC1 in cancer cells (2019) (1)
Mediating Tyrosine and Tryptophan Uptake (1)
Is nuclear protein localization receptor-mediated? (1988) (1)
Growth grows up: COCB themed issue on cell division, growth, and death. (2011) (1)
mTOR signaling in liver disease (2015) (1)
mTOR in Metabolic and Endocrine Disorders (2016) (1)
The EU and glomerular diseases (2012) (1)
Author response: A population of innate myelolymphoblastoid effector cell expanded by inactivation of mTOR complex 1 in mice (2017) (1)
Colitis is associated with loss of LHPP and up-regulation of histidine phosphorylation in intestinal epithelial cells (2020) (1)
Selective ATP-Competitive Inhibitors of TOR Suppress Rapamycin-Insensitive Function of TORC2 in S. cerevisiae (2012) (1)
Combining metformin with lactate transport inhibitors as a treatment modality for cancer - recommendation proposal (2022) (1)
TOR SIGNALLING: FROM BENCH TO BEDSIDE (2003) (1)
Erratum: FAP1, a homologue of human transcription factor NF-X1, competes with rapamycin for binding to FKBP12 in yeast (Molecular Microbiology (2001) 37:6 (1480-1493)) (2001) (0)
Raptor Ablation in Skeletal Muscle Affects the Structure and Function of the Excitation-Contraction Coupling Macromolecular Complex (2014) (0)
Studies on the mechanism of nuclear protein localization in yeast (1985) (0)
Views eIF 4 A moonlights as an off switch for TORC 1 (2016) (0)
Considerations on the mechanism of nuclear protein localization in yeast (1986) (0)
mTORC2 controls T-cell receptor processing and surface expression during thymocyte development (115.18) (2012) (0)
Preface/Front Matter (2004) (0)
Regional Bivalent-Univalent Pairing V ' m Trivalent Pairing of a Trisomic Chromosome in Saccharomyces cerewiiae (2002) (0)
Hepatic mTORC2 compensates for loss of adipose mTORC2 in mediating energy storage and glucose homeostasis (2022) (0)
1 1 2 3 4 AMPK and TOR : the Yin and Yang of cellular nutrient sensing and growth control 5 6 (2020) (0)
Multi-omics data integration reveals novel drug targets in hepatocellular carcinoma (2021) (0)
Evolutionarily conserved mechanism of insulin resistance (2018) (0)
Abstract 2197: A robotic genome-scale shRNA screen identifies metabolic drug targets and a glioblastoma gene signature (2010) (0)
TO R: The First 10 Years (2004) (0)
Novel epithelial cell models (2013) (0)
A mechanism to couple transport and export (1985) (0)
Correction for Jiang et al., Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease (2018) (0)
LYMPHOID NEOPLASIA Combined inhibition of PI3K-related DNA damage response kinases and mTORC1 induces apoptosis in MYC-driven B-cell lymphomas (2013) (0)
mTOR dependent transformed human cells have a distinct set of essential genes from bcr-abl transformed cells (2019) (0)
mTORC2 modulates {alpha}{beta}T-cell receptor processing and surface expression during thymocyte development (P4414) (2013) (0)
Novel roles of mTORC2 in regulation of insulin secretion by actin filament remodeling. (2022) (0)
TOR and Control of Cell Growth (2001) (0)
Loss of Rictor in Adipose Cells of PVAT Results in Upregulation of Inflammatory Mediators (0)
Drug discovery : rational serendipity (1996) (0)
Faculty Opinions recommendation of mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells. (2004) (0)
Abstract IA22: Mechanisms of evasive resistance in cancer (2016) (0)
Crystal structure of Chaetomium thermophilum Raptor (2015) (0)
Faculty Opinions recommendation of A nutrient sensor mechanism controls Drosophila growth. (2003) (0)
Heart Failure Cardiac Raptor Ablation Impairs Adaptive Hypertrophy, Alters Metabolic Gene Expression, and Causes Heart Failure in Mice (2011) (0)
Cytosplasm-to-nucleus signaling in yeast: use of immunosuppressive drugs as probes (1994) (0)
Impact papers on aging in 2009 Citation (2022) (0)
Elevated arginine levels in liver tumors promote metabolic reprogramming and tumor growth (2022) (0)
Author response: Regulation of human mTOR complexes by DEPTOR (2021) (0)
Raptor Knockout Mice Do Not Increase Heart Weight and Cardiomyocyte Cross-Sectional Area After Aortic Constriction , But Atrial and Brain Natriuretic Peptides (2011) (0)
Abstract 702: IMLEC: A population of innate myelolymphoblastoid effector cell expanded by inactivation of mTOR complex 1 (2018) (0)
NPR1 kinase and RSP5-BUL1/2 ubiquitin ligase control GLN3-dependent transcription in S. cerevisiae (2004) (0)
mTOR in health and in sickness (2015) (0)
mTOR signaling controls iNKT cell differentiation and effector function (HEM3P.278) (2014) (0)
Running title : TORC 1 responds to proteotoxic stress 1 2 Title 3 TORC 1 regulates autophagy induction in response to 4 proteotoxic stress in yeast and human cells 5 6 (2019) (0)
Inhibition of mTORC2/Akt signaling to enhance the therapeutic potential of CD8 T cells (2015) (0)
Abstract 4739: Genetic predisposition to DNA double strand break repair defect defines a new class of familial colon cancer (2015) (0)
Erratum to: Evolution of TOR and Translation Control (2016) (0)
Bidirectional crosstalk 2 between endoplasmic reticulum stress and mTOR 3 4 (2014) (0)
TOR signalling and control of cell growth in yeast and mammals (2008) (0)
Handbook of Cell Signaling (2009) (0)
Differentiation and Effector Function Orchestrates Invariant NKT Cell Mammalian Target of Rapamycin Complex 1 (2014) (0)
Glycine decarboxylation by renal cortical mitochondria in relation to renal serine synthesis (1984) (0)
Architecture of human mTOR Complex 1 - 5.9 Angstrom reconstruction (2015) (0)
Views Reduced C / EBP bLIP translation improves metabolic health (2015) (0)
FAP1, a homologue of human transcription factor NF‐X1, competes with rapamycin for binding to FKBP12 in yeast (2001) (0)
Expression during Thymocyte Development TCR Processing and Surface b a Modulates Mammalian Target of Rapamycin Complex 2 (2014) (0)
Profile of Michael N . Hall , 2017 Albert Lasker Basic Medical Research Awardee : Target of rapamycin , cell growth , and translational control (2017) (0)
Abstract 17895: Rictor in Perivascular Adipose Tissue Reduces Aortic Contraction by Controlling Inflammation (2013) (0)
THE RELATIONSHIP BETWEEN BIOMARKERS OF INFLAMMATION AND LEFT VENTRICULAR STRUCTURE AND FUNCTION (2021) (0)
Expression during Thymocyte Development TCR Processing and Surface !" Modulates Target of Rapamycin Complex 2 (2014) (0)
Mechanisms of allergy/immunology Epidermal mammalian target of rapamycin complex 2 controls lipid synthesis and ﬁlaggrin processing in epidermal barrier formation (2019) (0)
Adipose mTORC2 is essential for arborization of sensory neurons in white adipose tissue and whole-body energy homeostasis (2022) (0)
PRLLLSLAEQ GVLPKCLAYV DRNGRPLLCF FVSLVFGCIG FVATSDAEEQ SRTLCSMAHQ GLIPWWFGYI DRAGRPLVGI MANSLFGLLA FLVKSGSMSE SRILFGLSKN KLAPKFLSRT TKGGVPYIAV FVTAAFGALA YMETSTGGDK SRTMVALAEQ RFLPEIFSYV DRKGRPLVGI AVTSAFGLIA FVAASKKEGE SRCMVAMAHI GNLPKFLNRV DKRGRPMNAI LLTLFFGLLS FVAASDKQAE SRVLYSLART GNAPKQFGYV TRQ (0)
Author response: Architecture of the human mTORC2 core complex (2018) (0)
More writing: mTORC1 promotes m6A mRNA methylation. (2021) (0)
CHAPTER 314 – Translational Control by Amino Acids and Energy (2003) (0)
Abstract 514: Knockout of Rictor in Adipocytes Compromises Anticontractile Function of PVAT and Increases Mean Arterial Pressure (2014) (0)
The history and perspectives of TOR research (2011) (0)
TORC1 regulates autophagy induction in response to proteotoxic stress in yeast and human cells. (2019) (0)
Patterns of selection reveal shared molecular targets over short and long evolutionary timescales (2017) (0)
Yeast cloning book cloning (1996) (0)
Chapter 3 inhibition of mtorc 1 by astrin and Stress granules prevents apoptosis in cancer cells (2018) (0)
mTOR signalling and cellular metabolism are mutual determinants in cancer (2018) (0)

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