Michael R Edwards | Academic Influence

Why Is Michael R Edwards Influential?

Michael R Edwards's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Papers

Role of deficient type III interferon-λ production in asthma exacerbations (2006) (871)
Role of deficient type III interferon-lambda production in asthma exacerbations. (2006) (605)
The Airway Epithelium: Soldier in the Fight against Respiratory Viruses (2011) (531)
IL-33-dependent type 2 inflammation during rhinovirus-induced asthma exacerbations in vivo. (2014) (448)
Experimental rhinovirus infection as a human model of chronic obstructive pulmonary disease exacerbation. (2011) (351)
Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation (2008) (350)
Loss of ACTN3 gene function alters mouse muscle metabolism and shows evidence of positive selection in humans (2007) (292)
Co-ordinated Role of TLR3, RIG-I and MDA5 in the Innate Response to Rhinovirus in Bronchial Epithelium (2010) (283)
Azithromycin induces anti-viral responses in bronchial epithelial cells (2010) (274)
Rhinovirus-induced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammation (2014) (272)
Targeting the NF-κB pathway in asthma and chronic obstructive pulmonary disease (2008) (263)
Toll-Like Receptor 3 Is Induced by and Mediates Antiviral Activity against Rhinovirus Infection of Human Bronchial Epithelial Cells (2005) (239)
Host DNA released by NETosis promotes rhinovirus-induced type-2 allergic asthma exacerbation (2017) (205)
Respiratory virus induction of alpha‐, beta‐ and lambda‐interferons in bronchial epithelial cells and peripheral blood mononuclear cells (2009) (198)
Impaired innate interferon induction in severe therapy resistant atopic asthmatic children (2012) (185)
Control of lupus nephritis by changes of gut microbiota (2017) (178)
Rhinovirus 16-induced IFN-α and IFN-β are deficient in bronchoalveolar lavage cells in asthmatic patients. (2012) (175)
The microbiology of asthma (2012) (168)
Gut Microbiota in Human Systemic Lupus Erythematosus and a Mouse Model of Lupus (2017) (161)
Viral infections in allergy and immunology: How allergic inflammation influences viral infections and illness (2017) (144)
Novel antiviral properties of azithromycin in cystic fibrosis airway epithelial cells (2015) (139)
Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations (2018) (135)
Rhinovirus-induced interferon production is not deficient in well controlled asthma (2013) (121)
Th2 cytokines impair innate immune responses to rhinovirus in respiratory epithelial cells (2015) (121)
Vitamin D increases the antiviral activity of bronchial epithelial cells in vitro (2017) (112)
Combination therapy: Synergistic suppression of virus-induced chemokines in airway epithelial cells. (2006) (105)
Rhinovirus Replication in Human Macrophages Induces NF-κB-Dependent Tumor Necrosis Factor Alpha Production (2006) (102)
Rhinovirus induces MUC5AC in a human infection model and in vitro via NF-&kgr;B and EGFR pathways (2010) (96)
The role of macrolides in asthma: current evidence and future directions. (2014) (92)
A Comprehensive Evaluation of Nasal and Bronchial Cytokines and Chemokines Following Experimental Rhinovirus Infection in Allergic Asthma: Increased Interferons (IFN-γ and IFN-λ) and Type 2 Inflammation (IL-5 and IL-13) (2017) (86)
Enteric helminth‐induced type I interferon signaling protects against pulmonary virus infection through interaction with the microbiota (2017) (83)
Increased nuclear suppressor of cytokine signaling 1 in asthmatic bronchial epithelium suppresses rhinovirus induction of innate interferons (2015) (82)
Corticosteroids and β2 Agonists Differentially Regulate Rhinovirus-induced Interleukin-6 via Distinct Cis-acting Elements* (2007) (77)
The Role of IL-15 Deficiency in the Pathogenesis of Virus-Induced Asthma Exacerbations (2011) (73)
Obesity and susceptibility to severe outcomes following respiratory viral infection (2013) (70)
Defining critical roles for NF-κB p65 and type I interferon in innate immunity to rhinovirus (2012) (70)
Cytokine Responses to Rhinovirus and Development of Asthma, Allergic Sensitization, and Respiratory Infections during Childhood (2018) (65)
RSV-induced bronchial epithelial cell PD-L1 expression inhibits CD8+ T cell nonspecific antiviral activity. (2011) (64)
Immune response to vaccines is maintained in patients treated with dimethyl fumarate (2017) (62)
Mucosal Type 2 Innate Lymphoid Cells Are a Key Component of the Allergic Response to Aeroallergens (2017) (60)
Role of Xanthine Oxidase Activation and Reduced Glutathione Depletion in Rhinovirus Induction of Inflammation in Respiratory Epithelial Cells* (2008) (58)
Bronchial mucosal IFN-α/β and pattern recognition receptor expression in patients with experimental rhinovirus-induced asthma exacerbations (2019) (58)
Inhaled corticosteroid suppression of cathelicidin drives dysbiosis and bacterial infection in chronic obstructive pulmonary disease (2019) (54)
CXC chemokines and antimicrobial peptides in rhinovirus‐induced experimental asthma exacerbations (2014) (47)
Identification of novel macrolides with antibacterial, anti-inflammatory and type I and III IFN-augmenting activity in airway epithelium (2016) (45)
The influence of asthma control on the severity of virus-induced asthma exacerbations. (2015) (44)
Our Environment Shapes Us: The Importance of Environment and Sex Differences in Regulation of Autoantibody Production (2018) (44)
Addressing unmet needs in understanding asthma mechanisms (2017) (43)
Airway Epithelial Orchestration of Innate Immune Function in Response to Virus Infection. A Focus on Asthma. (2016) (42)
Innate activation of human primary epithelial cells broadens the host response to Mycobacterium tuberculosis in the airways (2017) (42)
Retinoic Acid-inducible Gene I-inducible miR-23b Inhibits Infections by Minor Group Rhinoviruses through Down-regulation of the Very Low Density Lipoprotein Receptor* (2011) (41)
RSV infection modulates IL-15 production and MICA levels in respiratory epithelial cells (2011) (41)
TLR3, TLR4 and TLRs7–9 Induced Interferons Are Not Impaired in Airway and Blood Cells in Well Controlled Asthma (2013) (39)
Role of Interleukin-1 and MyD88-Dependent Signaling in Rhinovirus Infection (2011) (38)
Lack of an exaggerated inflammatory response on virus infection in cystic fibrosis (2011) (37)
Protein kinase R, IκB kinase-β and NF-κB are required for human rhinovirus induced pro-inflammatory cytokine production in bronchial epithelial cells (2007) (36)
Mechanisms of adverse effects of β-agonists in asthma (2009) (36)
New treatment regimes for virus-induced exacerbations of asthma (2005) (36)
The potential of anti‐infectives and immunomodulators as therapies for asthma and asthma exacerbations (2017) (35)
Human Rhinovirus Impairs the Innate Immune Response to Bacteria in Alveolar Macrophages in Chronic Obstructive Pulmonary Disease. (2019) (35)
Immunoglobulin gene rearrangement, repertoire diversity, and the allergic response. (2003) (34)
Analysis of IgE Antibodies from a Patient with Atopic Dermatitis: Biased V Gene Usage and Evidence for Polyreactive IgE Heavy Chain Complementarity-Determining Region 31 (2002) (34)
IL-1β induces IL-8 in bronchial cells via NF-κB and NF-IL6 transcription factors and can be suppressed by glucocorticoids (2005) (34)
Impaired type I and type III interferon induction and rhinovirus control in human cystic fibrosis airway epithelial cells (2012) (34)
Viral Toll Like Receptor activation of pulmonary vascular smooth muscle cells results in endothelin-1 generation; relevance to pathogenesis of pulmonary arterial hypertension. (2012) (32)
Airway Epithelial Cells Generate Pro-inflammatory Tenascin-C and Small Extracellular Vesicles in Response to TLR3 Stimuli and Rhinovirus Infection (2019) (31)
Raised interferon‐β, type 3 interferon and interferon‐stimulated genes – evidence of innate immune activation in neutrophilic asthma (2017) (31)
Human rhinoviruses enter and induce proliferation of B lymphocytes (2017) (29)
Innate Immune Response to Viral Infections in Primary Bronchial Epithelial Cells is Modified by the Atopic Status of Asthmatic Patients (2018) (28)
Interferon response of the cystic fibrosis bronchial epithelium to major and minor group rhinovirus infection (2015) (26)
The Airway Epithelium: Soldier in the Fight against Respiratory Viruses (2011) (25)
Signalling pathways mediating type I interferon gene expression. (2007) (25)
Commercial rodent diets differentially regulate autoimmune glomerulonephritis, epigenetics and microbiota in MRL/lpr mice (2017) (25)
IL-1beta induces IL-8 in bronchial cells via NF-kappaB and NF-IL6 transcription factors and can be suppressed by glucocorticoids. (2005) (24)
Structural analysis of the ErbB‐2 receptor using monoclonal antibodies: Implications for receptor signalling (2003) (20)
The effectiveness of different rat IgG subclasses as IgE‐blocking antibodies in the rat basophil leukaemia cell model (1999) (20)
Development and characterization of DNAzyme candidates demonstrating significant efficiency against human rhinoviruses (2018) (19)
Interleukin-18 is associated with protection against rhinovirus-induced colds and asthma exacerbations. (2015) (18)
Protein kinase R, IkappaB kinase-beta and NF-kappaB are required for human rhinovirus induced pro-inflammatory cytokine production in bronchial epithelial cells. (2007) (18)
Pathogen Sensing Pathways in Human Embryonic Stem Cell Derived-Endothelial Cells: Role of NOD1 Receptors (2014) (18)
Human rhinovirus-induced inflammatory responses are inhibited by phosphatidylserine containing liposomes (2016) (16)
Anti‐inflammatory effects of the novel inhaled phosphodiesterase type 4 inhibitor CHF6001 on virus‐inducible cytokines (2016) (16)
Interferon-lambda as a new approach for treatment of allergic asthma? (2011) (15)
Anti-viral agents: potential utility in exacerbations of asthma (2013) (13)
Regulation of neonatal IgA production by the maternal microbiota (2021) (12)
Reduced sputum expression of interferon-stimulated genes in severe COPD (2016) (12)
Gut Microbiota and Bacterial DNA Suppress Autoimmunity by Stimulating Regulatory B Cells in a Murine Model of Lupus (2020) (11)
&bgr;2‐Agonists Enhance Asthma‐Relevant Inflammatory Mediators in Human Airway Epithelial Cells (2018) (10)
Deficient interferon in virus‐induced asthma exacerbations (2008) (9)
Efficacy of novel antibody‐based drugs against rhinovirus infection: In vitro and in vivo results (2017) (9)
Rhinovirus-induced CCL17 and CCL22 in Asthma Exacerbations and Differential Regulation by STAT6. (2020) (8)
Pulmonary Innate Lymphoid Cell Responses during Rhinovirus-induced Asthma Exacerbations In Vivo: A Clinical Trial. (2021) (8)
The application of phage display in allergy research: characterization of IgE, identification of allergens and development of novel therapeutics. (2001) (8)
17β-Estradiol and 17α-Ethinyl Estradiol Exhibit Immunologic and Epigenetic Regulatory Effects in NZB/WF1 Female Mice. (2019) (7)
Rhinovirus induction of fractalkine (CX3CL1) in airway and peripheral blood mononuclear cells in asthma (2017) (7)
Corrigendum: Host DNA released by NETosis promotes rhinovirus-induced type-2 allergic asthma exacerbation (2017) (6)
Low-dose 17α-ethinyl estradiol (EE) exposure exacerbates lupus renal disease and modulates immune responses to TLR7/9 agonists in genetically autoimmune-prone mice (2020) (6)
miR-122 promotes virus-induced lung disease by targeting SOCS1 (2021) (6)
Anti-viral activity of macrolide antibiotics 1 Azithromycin induces anti-viral responses in bronchial epithelial cells (2015) (4)
[Production of alpha-, beta-, and lambda-interferons by epithelial and mononuclear cells during acute respiratory viral infection]. (2006) (3)
RHINOVIRUS INDUCES MUC5AC IN A HUMAN INFECTION MODEL, & IN VITRO VIA NF-κB & EGFR PATHWAYS (2010) (3)
Retraction notice to "Efficacy of novel antibody-based drugs against rhinovirus infection: In vitro and in vivo results" [Antiviral Research 142 (2017) 185-192]. (2019) (3)
Genome-wide profiling of an enhancer-associated histone modification reveals the influence of asthma on the epigenome of the airway epithelium (2018) (3)
Differential Expression Of MicroRNA In Mycobacterium Tuberculosis-Infected Human Macrophages (2012) (3)
Volatile organic compound (VOC) analysis to differentiate between bacterial and viral respiratory infections in COPD (2018) (3)
Impaired innate immunity to rhinovirus in severe asthmatic children (2011) (2)
Virus-induced Volatile Organic Compounds are Detectable in Exhaled Breath During Pulmonary Infection. (2021) (2)
Diet and Microbes in the Pathogenesis of Lupus (2017) (2)
Profiling of H3K27Ac Reveals the Influence of Asthma on the Epigenome of the Airway Epithelium (2020) (2)
Evaluation of the Abbott Architect, Roche Elecsys and Virtus S1 SARS-CoV-2 antibody tests in community-managed COVID-19 cases (2020) (2)
In vivo bronchial epithelial interferon responses are augmented in asthma on day 4 following experimental rhinovirus infection (2022) (2)
Beclomethasone Has Lesser Suppressive Effects on Inflammation and Antibacterial Immunity Than Fluticasone or Budesonide in Experimental Infection Models (2020) (2)
Deficient production of IFN-stimulated genes upon rhinovirus infection in cystic fibrosis airway epithelial cells (2011) (2)
The effect of dietary phytoestrogen content on the development of systemic lupus erythematosus in the MRL/lpr mouse. (2016) (1)
Human rhinovirus-induced inflammatory responses are inhibited by phosphatidylserine containing liposomes (2017) (1)
Sex differences in innate anti-viral immune responses to respiratory viruses and in their clinical outcomes in a birth cohort study (2020) (1)
Enteric helminth-induced type-I interferon signalling protects against pulmonary virus (2019) (1)
Exacerbations of chronic respiratory diseases (2019) (1)
Effect of CRTH2 antagonism on the response to experimental rhinovirus infection in asthma: a pilot randomised controlled trial (2021) (1)
Pulmonary Innate Lymphoid Cell Responses During Rhinovirus-Induced Asthma Exacerbations (2018) (1)
Correction: The Role of IL-15 Deficiency in the Pathogenesis of Virus-Induced Asthma Exacerbations (2012) (1)
Correction: Co-ordinated Role of TLR3, RIG-I and MDA5 in the Innate Response to Rhinovirus in Bronchial Epithelium (2012) (1)
Whole Lung Transcriptome Analysis Of A Model Of Schistosomiasis-Associated Pulmonary Hypertension (2012) (1)
Type I conventional dendritic cells relate to disease severity in virus‐induced asthma exacerbations (2022) (1)
Reduced expression of interferon stimulated genes in refractory asthma (2012) (1)
Clinically Relevant β2-agonists Induce and Augment Rhinovirus-Induction of Asthma-Relevant Pro-Inflammatory Mediators in Human Bronchial Epithelial Cells (2020) (0)
Nuclear Suppressor Of Cytokine Signalling-1 Suppresses Rhinovirus Induced Interferon Expression And Is Associated With Impaired Interferon Expression In Asthma (2012) (0)
S119 Roles of TLR3, TLR4- and TLRs7–9 in Interferon Induction in Bronchial Epithelial Cells and Peripheral Blood Mononuclear Cells from Asthmatic and Non-Asthmatic Subjects (2012) (0)
mTOR modulates host immune responses to Francisella tularensis LVS infection (2012) (0)
Modulation of the inflammatory response of the CF airway epithelium upon viral infection (2010) (0)
Anti-inflammatory effects of the novel PDE4 inhibitor CHF6001 on virus inducible cytokines (2014) (0)
LSC - 2019 - RNA degradation is a deficient antiviral mechanism in the asthmatic airway epithelium (2019) (0)
MyD 88-dependent signaling in rhinoviral infection 1 2 (2011) (0)
Soluble mediators derived from bronchial epithelium are able to drive Th2 differentiation in the context of rhinovirus infection (2013) (0)
IL-33-induced neutrophilic inflammation and NETosis underlie rhinovirus-triggered exacerbations of asthma (2022) (0)
Type I Interferon Regulates Antiviral And Inflammatory Responses To Rhinovirus Infection In Vivo (2011) (0)
Reduced NF-ºB P65 Expression Inhibits Rhinovirus-Induced Inflammation Without Compromising Antiviral Immunity (2012) (0)
Rhinovirus Induced Type 1 Interferon (-α And –β) Are Deficient In BAL Cells In Asthma But Interferon Induction Pathways Appear Intact (2012) (0)
S137 Short-acting and long-acting β2-agonists upregulate asthma-relevant pro-inflammatory mediators in human airway epithelial cells while short-acting muscarinic antagonists do not (2019) (0)
The role of suppressor of cytokine signalling 1 (SOCS1) in virus-induced asthma exacerbations (2016) (0)
RNA degradation is a deficient antiviral mechanism in the asthmatic airway epithelium (2019) (0)
Development of antirhinoviral DNAzymes for effective prevention of asthma exacerbations: 299 (2019) (0)
A systems immunology approach to investigate cytokine responses to viruses and bacteria and their association with disease (2022) (0)
Retraction (2008) (0)
Respiratory Syncytial Virus (RSV) Detection Is Associated with an Increased Inflammatory Response in Stable (non-Exacerbating) Chronic Obstructive Pulmonary Disease (COPD) Patients (2019) (0)
Interleukin-4 Modulates Rhinovirus Replication and Antiviral Immune Response in Respiratory Epithelial Cells. (2009) (0)
ATS Abstract: IKK-ß Is Required For Rhinovirus Induced IFN-ß, IFN-» And Pro-inflammatory Cytokine Production In Vitro And In Vivo (2010) (0)
Suppressor of cytokine signalling 1 (SOCS1) and asthma exacerbations (2018) (0)
Type I and Type III Interferon Expression during Rhinovirus Infection (2008) (0)
S80 The role of MyD88 in rhinovirus 1B infection (2010) (0)
The CRTH2 Antagonist Timapiprant Does Not Alter the Response Rhinovirus Infection in Asthma: A Randomized, Placebo-Controlled Trial (2020) (0)
Differential interferon response of the cystic fibrosis bronchial epithelium to major and minor group rhinovirus infection (2015) (0)
LSC Abstract – Bacterial burden in rhinovirus-induced asthma exacerbations (2015) (0)
Immunity to virus infection (excluding retroviruses) (PP-025) (2010) (0)
Gut microbiota in human SLE and a mouse model of 1 lupus 2 3 4 (2017) (0)
Rhinovirus Induces IL-4, IL-5 And IL-13 In The Airways In Asthma But Not In Non-Atopic Subjects (2012) (0)
Development and Characterization of Antisense Oligonucleotides Against Human Rhinovirus for Efficient Prevention of Asthma Exacerbation (2019) (0)
Chain Complementarity-Determining Region and Evidence for Polyreactive IgE Heavy with Atopic Dermatitis: Biased V Gene Usage Analysis of IgE Antibodies from a Patient (2002) (0)
P235 Epigenetic landscape of the asthmatic airways (2016) (0)
Cystic fibrosis : new aspects of diagnosis , inflammation and detecting exacerbation 361 Intestinal current measurement ( ICM ) as a new diagnostic test for cystic fibrosis ( CF ) (2011) (0)
Interferon Response to Human Rhinovirus Is Impaired in Alveolar Macrophages but Not Bronchial Epithelial Cells in Chronic Obstructive Pulmonary Disease (2019) (0)
Deletion of microRNA-183-96-182 Cluster in Lymphocytes Suppresses Anti-DsDNA Autoantibody Production and IgG Deposition in the Kidneys in C57BL/6-Faslpr/lpr Mice (2022) (0)
Expression of alpha-, beta- and lambda-interferon upon during respiratory virus infection (2007) (0)
Role of Interleukin-1 and MyD88-Dependent Signaling in Rhinovirus Infection (cid:1) (2011) (0)
The role of IL-1 and MyD88-dependent signaling in rhinoviral infection 1 ऀð 2 ऀð (2011) (0)
Phosphatidylserine-containing liposomes: modulators of rhinovirus induced inflammatory responses (2013) (0)

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What Schools Are Affiliated With Michael R Edwards?

Michael R Edwards is affiliated with the following schools: