Michael Reiss
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Michael Reiss's Degrees
- PhD Physics University of Oxford
- Bachelors Computer Science Imperial College London
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(Suggest an Edit or Addition)Michael Reiss's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Locoregional relapse and distant metastasis in conservatively managed triple negative early-stage breast cancer. (2006) (1019)
- MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer. (2009) (386)
- Resistance to inhibition of cell growth by transforming growth factor-beta and its role in oncogenesis. (1993) (315)
- Phase I Study of GC1008 (Fresolimumab): A Human Anti-Transforming Growth Factor-Beta (TGFβ) Monoclonal Antibody in Patients with Advanced Malignant Melanoma or Renal Cell Carcinoma (2014) (310)
- ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis. (2009) (296)
- Missense mutations of the transforming growth factor beta type II receptor in human head and neck squamous carcinoma cells. (1995) (243)
- Alterations of Smad signaling in human breast carcinoma are associated with poor outcome: a tissue microarray study. (2002) (222)
- Ipsilateral breast tumor recurrence as a predictor of distant disease: implications for systemic therapy at the time of local relapse. (1996) (209)
- TGF-beta and cancer. (1999) (199)
- Differences in oxygen metabolism of phagocytosing monocytes and neutrophils. (1978) (198)
- Amelioration of Radiation-induced Fibrosis (2004) (183)
- Targeting the Transforming Growth Factor-β pathway inhibits human basal-like breast cancer metastasis (2010) (176)
- TGF- and cancer (1999) (163)
- Smads 2 and 3 are differentially activated by TGF-β in quiescent and activated hepatic stellate cells: Constitutive nuclear localization of Smads in activated cells is TGF-β independent (2003) (157)
- Inhibition of Growth and Metastasis of Mouse Mammary Carcinoma by Selective Inhibitor of Transforming Growth Factor-β Type I Receptor Kinase In vivo (2006) (156)
- Transforming Growth Factor β Type I Receptor Kinase Mutant Associated with Metastatic Breast Cancer (1998) (147)
- Smad2 and Smad3 play different roles in rat hepatic stellate cell function and alpha-smooth muscle actin organization. (2005) (145)
- Targeting Endogenous Transforming Growth Factor β Receptor Signaling in SMAD4-Deficient Human Pancreatic Carcinoma Cells Inhibits Their Invasive Phenotype 1 (2004) (140)
- Betaglycan inhibits TGF-beta signaling by preventing type I-type II receptor complex formation. Glycosaminoglycan modifications alter betaglycan function. (2002) (140)
- Transforming growth factor-β in breast cancer: A working hypothesis (1997) (126)
- Transforming Growth Factor-β1 Regulation of Collagenase-3 Expression in Osteoblastic Cells by Cross-talk between the Smad and MAPK Signaling Pathways and Their Components, Smad2 and Runx2* (2004) (123)
- Smads 2 and 3 are differentially activated by transforming growth factor-beta (TGF-beta ) in quiescent and activated hepatic stellate cells. Constitutive nuclear localization of Smads in activated cells is TGF-beta-independent. (2003) (121)
- Tumor necrosis factor stimulates epithelial tumor cell motility. (1991) (118)
- Transforming growth factor-β signaling: emerging stem cell target in metastatic breast cancer? (2009) (118)
- Structural alterations of transforming growth factor‐β receptor genes in human cervical carcinoma (1999) (117)
- Regulation of Growth and Differentiation of Human Keratinocytes by Type β Transforming Growth Factor and Epidermal Growth Factor (1987) (117)
- Ovarian cancer detection by logical analysis of proteomic data (2004) (116)
- Loss of Smad Signaling in Human Colorectal Cancer Is Associated with Advanced Disease and Poor Prognosis (2003) (113)
- Induction of tumor cell differentiation as a therapeutic approach: preclinical models for hematopoietic and solid neoplasms. (1986) (111)
- Insulin-like Growth Factor-I Inhibits Transcriptional Responses of Transforming Growth Factor-β by Phosphatidylinositol 3-Kinase/Akt-dependent Suppression of the Activation of Smad3 but Not Smad2* (2003) (102)
- TGFBR1*6A and cancer: a meta-analysis of 12 case-control studies. (2004) (96)
- Status of the p53 tumor suppressor gene in human squamous carcinoma cell lines. (1992) (95)
- Reappraisal of the role of axillary lymph node dissection in the conservative treatment of breast cancer. (1997) (94)
- Activation of the autocrine transforming growth factor alpha pathway in human squamous carcinoma cells. (1991) (87)
- Identification of Function for CD44 Intracytoplasmic Domain (CD44-ICD) (2012) (86)
- Novel inactivating mutations of transforming growth factor‐β type I receptor gene in head‐and‐neck cancer metastases (2001) (83)
- TLP, a novel modulator of TGF‐β signaling, has opposite effects on Smad2‐ and Smad3‐dependent signaling (2003) (82)
- Transforming growth factor-beta and cancer: a love-hate relationship? (1997) (79)
- Breast cancer prognosis by combinatorial analysis of gene expression data (2006) (76)
- Gene expression profiling changes induced by a novel Gemini Vitamin D derivative during the progression of breast cancer. (2006) (75)
- Transforming growth factor beta signaling is disabled early in human endometrial carcinogenesis concomitant with loss of growth inhibition. (2002) (75)
- Phase I/II study of GC1008: A human anti-transforming growth factor-beta (TGF{beta}) monoclonal antibody (MAb) in patients with advanced malignant melanoma (MM) or renal cell carcinoma (RCC) (2008) (75)
- Mutant p53 tumor suppressor gene causes resistance to transforming growth factor beta 1 in murine keratinocytes. (1993) (75)
- Modulation of the terminal differentiation of human squamous carcinoma cells in vitro by all-trans-retinoic acid. (1985) (72)
- ImageMiner: a software system for comparative analysis of tissue microarrays using content-based image retrieval, high-performance computing, and grid technology (2011) (69)
- Frequent alterations of Smad signaling in human head and neck squamous cell carcinomas: a tissue microarray analysis. (2003) (69)
- Cloning of putative growth regulatory genes from primary human keratinocytes by subtractive hybridization. (1995) (66)
- Loss of transforming growth factor-beta type II receptor gene expression in primary human esophageal cancer. (1996) (64)
- Frequent inactivation of the transforming growth factor beta type II receptor in small-cell lung carcinoma cells. (1997) (63)
- Cancer-associated transforming growth factor beta type II receptor gene mutant causes activation of bone morphogenic protein-Smads and invasive phenotype. (2008) (61)
- A prototype for unsupervised analysis of tissue microarrays for cancer research and diagnostics (2004) (59)
- A mutation in the transforming growth factor beta type II receptor gene promoter associated with loss of gene expression. (1996) (59)
- Analysis of PTHRP binding and signal transduction mechanisms in benign and malignant squamous cells. (1992) (59)
- Transforming growth factor beta type I receptor kinase mutant associated with metastatic breast cancer. (1998) (55)
- Terfenadine (Seldane): a new drug for restoring sensitivity to multidrug resistant cancer cells. (1993) (55)
- PET with the 89Zr-Labeled Transforming Growth Factor-β Antibody Fresolimumab in Tumor Models (2011) (54)
- Functional evidence for an extracellular calcium receptor mechanism triggering tyrosine kinase activation associated with mouse keratinocyte differentiation. (1994) (49)
- Detection and viability of tumor cells in peripheral blood stem cell and bone marrow collections from breast cancer patients. (1994) (48)
- MTDH Activation by 8 q 22 Genomic Gain Promotes Chemoresistance and Metastasis of Poor-Prognosis Breast Cancer (2008) (47)
- Transforming growth factor-beta in breast cancer: a working hypothesis. (1997) (45)
- Selective inhibitors of type I receptor kinase block cellular transforming growth factor-beta signaling. (2004) (41)
- High frequency of resistance of human squamous carcinoma cells to the anti-proliferative action of transforming growth factor beta. (1990) (41)
- Extracellular calcium‐dependent regulation of transmembrane calcium fluxes in murine keratinocytes (1991) (39)
- Bcl-2 antisense oligodeoxynucleotide therapy of Epstein-Barr virus-associated lymphoproliferative disease in severe combined immunodeficient mice. (2000) (39)
- Bcl-2 antisense (G3139, Genasense) enhances the in vitro and in vivo response of Epstein-Barr virus-associated lymphoproliferative disease to rituximab. (2003) (38)
- Cloning and genomic organization of the human transforming growth factor-beta type I receptor gene. (1997) (35)
- Trifluoperazine as a modulator of multidrug resistance in refractory breast cancer (1996) (35)
- Estrogen-dependent prognostic significance of cyclooxygenase-2 expression in early-stage invasive breast cancers treated with breast-conserving surgery and radiation. (2008) (34)
- Transforming growth factor (TGF)-β expression and activation mechanisms as potential targets for anti-tumor therapy and tumor imaging. (2012) (34)
- Use of the ODD-Luciferase Transgene for the Non-Invasive Imaging of Spontaneous Tumors in Mice (2011) (34)
- Long-term assessment of cardiac function after dose-dense and -intense sequential doxorubicin (A), paclitaxel (T), and cyclophosphamide (C) as adjuvant therapy for high risk breast cancer (2007) (33)
- Detection and viability of tumor cells in peripheral blood stem cell and bone marrow collections from breast cancer patients [letter; comment] (1994) (32)
- Transfer of chromosome 18 into human head and neck squamous carcinoma cells: evidence for tumor suppression by Smad4/DPC4. (1997) (31)
- Alterations of transforming growth factor-beta 1 receptor type II occur in ulcerative colitis-associated carcinomas, sporadic colorectal neoplasms, and esophageal carcinomas, but not in gastric neoplasms. (1996) (29)
- Alterations of Smad expression and activation in defining 2 subtypes of human head and neck squamous cell carcinoma (2013) (29)
- Smad protein expression and activation in transforming growth factor-beta refractory human squamous cell carcinoma cells. (2001) (27)
- Constitutive Smad linker phosphorylation in melanoma: a mechanism of resistance to transforming growth factor‐β‐mediated growth inhibition (2011) (27)
- Luminal breast cancer metastasis is dependent on estrogen signaling (2012) (25)
- Unsupervised imaging, registration and archiving of tissue microarrays (2002) (25)
- Resistance of human squamous carcinoma cells to transforming growth factor beta 1 is a recessive trait. (1993) (24)
- Functional characterization of transforming growth factor beta type II receptor mutants in human cancer. (1998) (24)
- Regulation of growth and differentiation of human keratinocytes by type beta transforming growth factor and epidermal growth factor. (1987) (24)
- Antisense to the Epstein‐Barr virus (EBV)‐encoded latent membrane protein 1 (LMP‐1) sensitizes EBV‐immortalized B cells to transforming growth factor‐beta and chemotherapeutic agents (2001) (23)
- Wild-type p53 tumor suppressor gene restores differentiation of human squamous carcinoma cells but not the response to transforming growth factor beta. (1993) (23)
- Interferon-inducible protein 10 as a possible factor in the pathogenesis of cutaneous T-cell lymphomas. (1997) (22)
- A Novel Vitamin D Derivative Activates Bone Morphogenetic Protein Signaling in MCF10 Breast Epithelial Cells (2006) (21)
- Reversible effects of retinoic acid on glycosaminoglycan synthesis during differentiation of HL-60 leukemia cells. (1985) (20)
- Cryopreservation of human monocytes. (1981) (20)
- Modulation of cell shedding and glycosaminoglycan synthesis of human malignant keratinocytes by all-trans-retinoic acid and hydrocortisone in vitro. (1986) (18)
- Interferon-inducible protein-10 and the pathogenesis of cutaneous T-cell lymphomas. (1996) (16)
- Promoter-independent regulation of vimentin expression in mammary epithelial cells by val(12)ras and TGFbeta. (2007) (15)
- Smads 2 and 3 Are Differentially Activated by Transforming Growth Factor-β (TGF-β) in Quiescent and Activated Hepatic Stellate Cells (2003) (14)
- Betaglycan Inhibits TGF-β Signaling by Preventing Type I-Type II Receptor Complex Formation (2002) (14)
- Uncoupling of the calcium-induced terminal differentiation and the activation of membrane-associated transglutaminase in murine keratinocytes by type-beta transforming growth factor. (1989) (14)
- Separation of lymphoid-line cells according to volume and density. (1974) (13)
- Down-regulation of glucocorticoid binding sites by retinoic acid in squamous carcinoma cells resistant to the induction of keratinization by hydrocortisone. (1988) (12)
- A Clinically Motivated 2-Fold Framework for Quantifying and Classifying Immunohistochemically Stained Specimens (2007) (9)
- Five-Year Update of an Expanded Phase II Study of Dose-Dense and -Intense Doxorubicin, Paclitaxel and Cyclophosphamide (ATC) in High-Risk Breast Cancer (2005) (8)
- Transforming Growth Factor-β Signaling Strength Determines Target Gene Expression Profile in Human Keratinocytes (2008) (7)
- Adjuvant sequential dose-dense doxorubicin, paclitaxel, and cyclophosphamide (ATC) for high-risk breast cancer is feasible in the community setting. (1999) (7)
- Decentralized Data Sharing of Tissue Microarrays for Investigative Research in Oncology (2006) (6)
- A metabolic comparison between human blood monocytes and neutrophils. (1979) (6)
- Mechanisms involved in the induction of malignant cell differentiation. (1986) (6)
- Prognostic factors in primary breast cancer. (1989) (6)
- Restoration of differentiation and suppression of tumorigenicity in somatic cell hybrids of human squamous carcinoma cells and keratinocytes. (1994) (5)
- p53 polymorphisms at position 72 and development of cervical cancer (1998) (5)
- Bovine papillomavirus type I induces resistance to Ca+(+)-induced terminal differentiation in murine keratinocytes. (1989) (4)
- Reinitiation of DNA synthesis in quiescent mouse keratinocytes; Regulation by polypeptide hormones, cholera toxin, dexamethasone, and retinoic acid (1988) (4)
- Transforming Growth Factor β pathway antagonists inhibit human breast cancer metastases to lung and bone (2007) (4)
- Sequential High‐Dose Alkylating Therapy and Stem Cell Support for High‐Risk Stage III Breast Cancer (2003) (3)
- Targeting Transforming Growth Factor-β in Metastasis: In Vitro and In Vivo Mechanisms (2008) (3)
- Constitutive expression of the c-fos protooncogene in murine keratinocytes: potentiation of the mitogenic response to insulin-like growth factor 1. (1990) (3)
- Combinatorial Analysis of Breast Cancer Data from Gene Expression Microarrays (2003) (3)
- Alterations of Transforming Growth Factor-β Signaling in Squamous Cell Carcinomas (2011) (2)
- Abstract #5667: ADAMTS1 and MMP1 promote breast cancer bone metastasis through a bone stromal cell-mediated osteolytic signaling cascade (2009) (2)
- Abstract 2118: Phenotypic diversity of disease-associated transforming growth factor-β (TGF-β) type I receptor gene (TGFBR1) mutants (2011) (1)
- Advances in Brief Bcl-2 Antisense Oligodeoxynucleotide Therapy of Epstein-Barr Virus-associated Lymphoproliferative Disease in Severe Combined Immunodeficient Mice 1 (2000) (1)
- Abstract 786: Alterations of TGFβ/Smad signaling in human head and neck squamous cell carcinomas (2010) (1)
- Local-regional relapse and distant metastasis in conservatively managed triple negative early stage breast cancer. (2006) (1)
- 37 Targeting Transforming GrowthFactor-ji in Metastasis : In Vitro and In Vivo Mechanisms (0)
- Associated with Poor Outcome : A Tissue Microarray Study Alterations of Smad Signaling in Human Breast Carcinoma Are Updated (2002) (0)
- Abstract 4940: Role of Smad3 linker phosphorylation in breast cancer progression (2015) (0)
- Reversible Effects of Retinole Acid on Glycosaminoglycan Synthesis during Differentiation of HL-60 Leukemia Cells1 (2006) (0)
- Transforming Growth Factor-B Receptors in Human Breast Cancer (1998) (0)
- Small Volume Viscometer By (2007) (0)
- Estrogen-Dependent Prognostic Significance of COX-2 in Early Stage Invasive Breast Cancer (2007) (0)
- Abstract 5236: Development of chronic disease model of metastatic estrogen receptor positive (ER+) breast cancer (BC) (2011) (0)
- Chromosome 18 appears to restore response to TGFB in the squamous cell carcinoma cell line, FaDu☆ (1993) (0)
- TGFbeta Type I Receptor Kinase Inhibitors - A Novel Treatment for Breast Cancer (2001) (0)
- A Genomic Approach to the Treatment of Breast Cancer (2002) (0)
- Cells II Receptor in Human Head and Neck Squamous Carcinoma Type β Missense Mutations of the Transforming Growth Factor Updated (2006) (0)
- Morphogenic Protein-Smads and Invasive Phenotype Receptor Gene Mutant Causes Activation of Bone Type II β Cancer-Associated Transforming Growth Factor (2008) (0)
- Type I Receptor Kinase Inhibitors - A Novel Treatment for Breast Cancer (2002) (0)
- Regulation of Growth and Differentiation of Human Keratinocytes by Type ß Transforming Growth Factor and Epidermal Growth Factor1 (2006) (0)
- NUMBER DAMD 1796-1-6024 TITLE : Transforming Growth Factor-ß Receptors in Human Breast Cancer (0)
- 2036 The natural history of local regional breast cancer recurrence: Prognosis and implications for systemic therapy (1997) (0)
- Abstract 5763: VCAM1 mediates aggressive bone metastasis outbreak from tumor dormancy by engaging α4β1-positive osteoclast progenitor cells (2010) (0)
- Tumor Necrosis Factor Stimulates Epithelial Tumor Cell Motility 1 (1991) (0)
- Minute Volume Viscometer (2005) (0)
- Transforming Growth Factor-B Receptors in Humans (2001) (0)
- Transforming Growth Factor-beta Receptors in Human Breast Cancer. (1997) (0)
- Structure-function studies of disease-associated transforming growth factor type II receptor mutations (2007) (0)
- Luminal breast cancer metastasis is dependent on estrogen signaling (2012) (0)
- Third Design Minute Volume Viscometer (2007) (0)
- Preprint – To appear in the Proceedings of the American Medical Informatics Association 3 (2002) (0)
- A young woman with recurrence of breast cancer. (2002) (0)
- Abstract 4889: Transforming growth factor-β signaling in breast cancer subtypes (2010) (0)
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