Michael Steven Denison
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Michael Steven Denisonearth-sciences Degrees
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Environmental Science
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Michael Steven Denisonbiology Degrees
Biology
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Ecology
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Earth Sciences Biology
Michael Steven Denison's Degrees
- PhD Toxicology University of California, Berkeley
- Masters Environmental Science Stanford University
Why Is Michael Steven Denison Influential?
(Suggest an Edit or Addition)Michael Steven Denison's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The 2005 World Health Organization reevaluation of human and Mammalian toxic equivalency factors for dioxins and dioxin-like compounds. (2006) (3169)
- Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals. (2003) (1750)
- Aryl Hydrocarbon Receptor Antagonists Promote the Expansion of Human Hematopoietic Stem Cells (2010) (931)
- Exactly the same but different: promiscuity and diversity in the molecular mechanisms of action of the aryl hydrocarbon (dioxin) receptor. (2011) (615)
- Aryl hydrocarbon receptor control of a disease tolerance defence pathway (2014) (502)
- Ligand binding and activation of the Ah receptor. (2002) (467)
- The DNA recognition site for the dioxin-Ah receptor complex. Nucleotide sequence and functional analysis. (1988) (409)
- Species-specific recombinant cell lines as bioassay systems for the detection of 2,3,7,8-tetrachlorodibenzo-p-dioxin-like chemicals. (1996) (377)
- Ah Receptor and NF-κB Interactions, a Potential Mechanism for Dioxin Toxicity* (1999) (371)
- Xenobiotic-inducible Transcription of Cytochrome P450 Genes (*) (1995) (364)
- Chemical-activated luciferase gene expression (CALUX): a novel in vitro bioassay for Ah receptor active compounds in sediments and pore water. (1996) (358)
- In Vitro Biologic Activities of the Antimicrobials Triclocarban, Its Analogs, and Triclosan in Bioassay Screens: Receptor-Based Bioassay Screens (2008) (335)
- Activation of the Ah receptor signal transduction pathway by bilirubin and biliverdin. (1998) (294)
- Functional aspects of developmental toxicity of polyhalogenated aromatic hydrocarbons in experimental animals and human infants. (1995) (281)
- Activation of the Ah receptor by tryptophan and tryptophan metabolites. (1998) (278)
- The Ah Receptor: A Regulator of the Biochemical and Toxicological Actions of Structurally Diverse Chemicals (1998) (263)
- Comparison of Ah receptor-mediated luciferase and ethoxyresorufin-O-deethylase induction in H4IIE cells: implications for their use as bioanalytical tools for the detection of polyhalogenated aromatic hydrocarbons. (1996) (249)
- CH223191 is a ligand-selective antagonist of the Ah (Dioxin) receptor. (2010) (216)
- Inducible, receptor-dependent protein-DNA interactions at a dioxin-responsive transcriptional enhancer. (1988) (211)
- Protein-DNA interactions at recognition sites for the dioxin-Ah receptor complex. (1989) (209)
- Induction of Cyp1a1 Is a Nonspecific Biomarker of Aryl Hydrocarbon Receptor Activation: Results of Large Scale Screening of Pharmaceuticals and Toxicants in Vivo and in Vitro (2007) (201)
- Polybrominated dibenzo-p-dioxins, dibenzofurans, and biphenyls: inclusion in the toxicity equivalency factor concept for dioxin-like compounds. (2013) (178)
- Species-specific antagonism of Ah receptor action by 2,2',5,5'-tetrachloro- and 2,2',3,3'4,4'-hexachlorobiphenyl. (1995) (176)
- Ah receptor and NF-kappaB interactions, a potential mechanism for dioxin toxicity. (1999) (169)
- Structure and function of the Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Species difference in molecular properties of the receptors from mouse and rat hepatic cytosols. (1986) (168)
- Cross-talk between Aryl Hydrocarbon Receptor and the Inflammatory Response (2013) (165)
- Recombinant cell bioassays for endocrine disruptors: development of a stably transfected human ovarian cell line for the detection of estrogenic and anti-estrogenic chemicals. (2000) (156)
- Development of a bioanalytical test battery for water quality monitoring: Fingerprinting identified micropollutants and their contribution to effects in surface water. (2017) (156)
- Induction and inhibition of aromatase (CYP19) activity by natural and synthetic flavonoid compounds in H295R human adrenocortical carcinoma cells. (2004) (153)
- Activation of the Ah Receptor Signaling Pathway by Prostaglandins (2001) (144)
- Linking in Vitro Effects and Detected Organic Micropollutants in Surface Water Using Mixture-Toxicity Modeling. (2015) (141)
- Relationship between Estrogen Receptor-Binding and Estrogenic Activities of Environmental Estrogens and Suppression by Flavonoids (2002) (141)
- DNA sequence determinants for binding of transformed Ah receptor to a dioxin-responsive enhancer. (1992) (128)
- Structural and functional characterization of the aryl hydrocarbon receptor ligand binding domain by homology modeling and mutational analysis. (2007) (124)
- Activation of the Ah receptor by extracts of dietary herbal supplements, vegetables, and fruits. (2003) (123)
- Malassezia yeasts produce a collection of exceptionally potent activators of the Ah (dioxin) receptor detected in diseased human skin. (2013) (123)
- Detection of the TCDD binding-fingerprint within the Ah receptor ligand binding domain by structurally driven mutagenesis and functional analysis. (2009) (116)
- Activation of the aryl hydrocarbon receptor is essential for mediating the anti-inflammatory effects of a novel low-molecular-weight compound. (2008) (108)
- Ah receptor-based chemical screening bioassays: application and limitations for the detection of Ah receptor agonists. (2000) (107)
- Development of a green fluorescent protein-based cell bioassay for the rapid and inexpensive detection and characterization of ah receptor agonists. (2002) (107)
- Recombinant cell bioassay systems for the detection and relative quantitation of halogenated dioxins and related chemicals. (2004) (105)
- Ligand Promiscuity of Aryl Hydrocarbon Receptor Agonists and Antagonists Revealed by Site-Directed Mutagenesis (2014) (104)
- Development of basal and induced aryl hydrocarbon (benzo[a]pyrene) hydroxylase activity in the chicken embryo in ovo. (1983) (103)
- Effects of polybrominated diphenyl ethers on basal and TCDD-induced ethoxyresorufin activity and cytochrome P450-1A1 expression in MCF-7, HepG2, and H4IIE cells. (2004) (102)
- Comparative studies on the effects of green tea extracts and individual tea catechins on human CYP1A gene expression. (2000) (101)
- Comparison of recombinant cell bioassays for the detection of Ah receptor agonists (2004) (100)
- Independent actions on cyclin-dependent kinases and aryl hydrocarbon receptor mediate the antiproliferative effects of indirubins (2004) (100)
- Chemically activated luciferase gene expression (CALUX) cell bioassay analysis for the estimation of dioxin-like activity: critical parameters of the CALUX procedure that impact assay results. (2005) (98)
- Induction of drug-metabolizing enzymes: mechanisms and consequences. (1986) (96)
- alpha-Naphthoflavone-induced CYP1A1 gene expression and cytosolic aryl hydrocarbon receptor transformation. (1993) (95)
- Analysis of Ah receptor pathway activation by brominated flame retardants. (2004) (90)
- Assessing the estrogenic and dioxin-like activities of chemicals and complex mixtures using in vitro recombinant receptor-reporter gene assays. (1996) (88)
- Organization and function of a dioxin-responsive enhancer. (1990) (86)
- Ultraviolet photoproducts of tryptophan can act as dioxin agonists. (1991) (86)
- Atmospheric concentrations of polybrominated diphenyl ethers at near-source sites. (2007) (85)
- Development of toxic equivalency factors for PCB congeners and the assessment of TCDD and PCB mixtures in rainbow trout (1995) (84)
- Interactions of polybrominated diphenyl ethers with the aryl hydrocarbon receptor pathway. (2006) (81)
- Re Human and Mammalian Toxic Equivalency Factors for Dioxins and Dioxin-Like Compounds: The Who 2005 Re-Evaluation (2006) (80)
- Low inducibility of CYP1A activity by polychlorinated biphenyls (PCBs) in flounder (Platichthys flesus): characterization of the Ah receptor and the role of CYP1A inhibition. (1998) (77)
- Carbaryl, a carbamate insecticide, is a ligand for the hepatic Ah (dioxin) receptor. (1998) (76)
- Neutrophil function after exposure to polychlorinated biphenyls in vitro. (1993) (76)
- The calux (chemical‐activated luciferase expression) assay adapted and validated for measuring TCDD equivalents in blood plasma (1997) (75)
- Role of the Per/Arnt/Sim Domains in Ligand-dependent Transformation of the Aryl Hydrocarbon Receptor* (2008) (75)
- The in vivo estrogenic and in vitro anti‐estrogenic activity of permethrin and bifenthrin (2012) (73)
- New Aryl Hydrocarbon Receptor Homology Model Targeted To Improve Docking Reliability (2011) (72)
- Development and modification of a recombinant cell bioassay to directly detect halogenated and polycyclic aromatic hydrocarbons in serum. (2000) (69)
- Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin: Comparative studies in mammalian and nonmammalian species (1986) (68)
- And Now for Something Completely Different: Diversity in Ligand-Dependent Activation of Ah Receptor Responses. (2017) (68)
- Species-specific binding of transformed Ah receptor to a dioxin responsive transcriptional enhancer. (1992) (68)
- Persistent binding of ligands to the aryl hydrocarbon receptor. (2007) (66)
- Induction of Cytochrome P450 Enzymes That Metabolize Xenobiotics (1995) (66)
- Third-generation Ah receptor-responsive luciferase reporter plasmids: amplification of dioxin-responsive elements dramatically increases CALUX bioassay sensitivity and responsiveness. (2011) (66)
- Regulation of prostaglandin endoperoxide H synthase-2 expression by 2,3,7,8,-tetrachlorodibenzo-p-dioxin. (1996) (66)
- Toxicology in the Fast Lane: Application of High-Throughput Bioassays to Detect Modulation of Key Enzymes and Receptors (2009) (64)
- An in vitro rainbow trout cell bioassay for aryl hydrocarbon receptor‐mediated toxins (1997) (63)
- The silencing mediator of retinoic acid and thyroid hormone receptors can interact with the aryl hydrocarbon (Ah) receptor but fails to repress Ah receptor-dependent gene expression. (2002) (61)
- Comparative analysis of homology models of the AH receptor ligand binding domain: verification of structure-function predictions by site-directed mutagenesis of a nonfunctional receptor. (2013) (61)
- Analysis of the antiestrogenic activity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in human ovarian carcinoma BG-1 cells. (2002) (61)
- Sustained activation of the Aryl hydrocarbon Receptor transcription factor promotes resistance to BRAF-inhibitors in melanoma (2018) (60)
- Aryl hydrocarbon receptor is activated in patients and mice with chronic kidney disease. (2018) (59)
- Characterization of the interaction of transformed rat hepatic cytosolic Ah receptor with a dioxin responsive transcriptional enhancer. (1991) (57)
- Identification of the Ah receptor in selected mammalian species and induction of aryl hydrocarbon hydroxylase. (1985) (55)
- Development of Species-Specific Ah Receptor-Responsive Third Generation CALUX Cell Lines with Enhanced Responsiveness and Improved Detection Limits. (2015) (53)
- Effects of Neonicotinoids on Promoter-Specific Expression and Activity of Aromatase (CYP19) in Human Adrenocortical Carcinoma (H295R) and Primary Umbilical Vein Endothelial (HUVEC) Cells. (2016) (52)
- Effects of histone deacetylase inhibitors on the Ah receptor gene promoter. (2000) (50)
- Production of a novel recombinant cell line for use as a bioassay system for detection of 2,3,7,8‐tetrachlorodibenzo‐P‐dioxin‐like chemicals (1994) (50)
- Ah-receptor-dependent modulation of gene expression by aged and diluted sidestream cigarette smoke. (1996) (50)
- Hepatic Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Partial stabilization by molybdate. (1986) (50)
- Pelargonidin activates the AhR and induces CYP1A1 in primary human hepatocytes and human cancer cell lines HepG2 and LS174T. (2013) (48)
- Analysis of the murine AhR gene promoter (2000) (48)
- Analysis of the Aryl Hydrocarbon Receptor (AhR) Signal Transduction Pathway (2002) (48)
- Modeling the binding of diverse ligands within the Ah receptor ligand binding domain (2019) (48)
- Comparative gene responses to collected ambient particles in vitro: endothelial responses. (2011) (48)
- Identification of novel Ah receptor agonists using a high-throughput green fluorescent protein-based recombinant cell bioassay. (2002) (47)
- Pityriazepin and other potent AhR ligands isolated from Malassezia furfur yeast. (2015) (44)
- Gas-Phase Ambient Air Contaminants Exhibit Significant Dioxin-like and Estrogen-like Activity in Vitro (2005) (44)
- Binding of transformed Ah receptor complex to a dioxin responsive transcriptional enhancer: evidence for two distinct heteromeric DNA-binding forms. (1993) (44)
- Effects of estrogenic compounds on immunoglobulin production by mouse splenocytes. (2002) (43)
- A novel prenylflavone restricts breast cancer cell growth through AhR-mediated destabilization of ERα protein. (2012) (43)
- Trace contamination with dioxin-like chemicals: evaluation of bioassay-based TEQ determination for hazard assessment and regulatory responses (2001) (42)
- Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin: ontogeny in chick embryo liver. (1986) (42)
- Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Codistribution of unoccupied receptor with cytosolic marker enzymes during fractionation of mouse liver, rat liver and cultured Hepa-1c1 cells. (1986) (42)
- AHR Ligands: Promiscuity in Binding and Diversity in Response (2011) (41)
- Ligand Displaces Heat Shock Protein 90 from Overlapping Binding Sites within the Aryl Hydrocarbon Receptor Ligand-binding Domain* (2011) (41)
- Inhibition of intercellular communication by 2,3,7,8-tetrachlorodibenzo-p-dioxin and dioxin-like PCBs in mouse hepatoma cells (Hepa1c1c7): involvement of the Ah receptor. (1994) (40)
- The binding of transformed aromatic hydrocarbon (Ah) receptor to its DNA recognition site is not affected by metal depletion (1990) (40)
- Characterization and potential environmental risks of leachate from shredded rubber mulches. (2009) (40)
- From ‘Omics to Otoliths: Responses of an Estuarine Fish to Endocrine Disrupting Compounds across Biological Scales (2013) (39)
- Chemicals having estrogenic activity can be released from some bisphenol a-free, hard and clear, thermoplastic resins (2014) (39)
- Determination of PCDD/Fs, PBDD/Fs and dioxin-like PCBs in human milk from mothers residing in the rural areas in Flanders, using the CALUX bioassay and GC-HRMS. (2013) (37)
- Newspapers and newspaper ink contain agonists for the ah receptor. (2008) (37)
- Considerations for potency equivalent calculations in the Ah receptor-based CALUX bioassay: normalization of superinduction results for improved sample potency estimation. (2011) (37)
- Harmaline and harmalol inhibit the carcinogen-activating enzyme CYP1A1 via transcriptional and posttranslational mechanisms. (2012) (36)
- Selectivity of 1-phenylimidazole as a ligand for cytochrome P-450 and as an inhibitor of microsomal oxidation. (1983) (36)
- In vitro transformation of the human Ah receptor and its binding to a dioxin response element. (1992) (35)
- Transient expression of CYP1A1 in rat epithelial cells cultured in suspension. (2001) (35)
- Ah-receptor mediated luciferase expression: a tool for monitoring dioxin-like toxicity. (1993) (34)
- Enhancing the response of CALUX and CAFLUX cell bioassays for quantitative detection of dioxin-like compounds (2010) (33)
- Editor’s Highlight: Microbial-Derived 1,4-Dihydroxy-2-naphthoic Acid and Related Compounds as Aryl Hydrocarbon Receptor Agonists/Antagonists Structure–Activity Relationships and Receptor Modeling (2017) (33)
- Comparative studies of aryl hydrocarbon hydroxylase and the Ah receptor in nonmammalian species. (1985) (32)
- Dioxinlike properties of a trichloroethylene combustion-generated aerosol. (1996) (32)
- Metformin inhibits 7,12-dimethylbenz[a]anthracene-induced breast carcinogenesis and adduct formation in human breast cells by inhibiting the cytochrome P4501A1/aryl hydrocarbon receptor signaling pathway. (2015) (31)
- Identification of benzothiazole derivatives and polycyclic aromatic hydrocarbons as aryl hydrocarbon receptor agonists present in tire extracts (2011) (30)
- Identification of a Novel Cis-acting Negative Regulatory Element Affecting Expression of the CYP1A1 Gene in Rat Epidermal Cells* (1996) (30)
- Protein kinase C is not involved in Ah receptor transformation and DNA binding. (1993) (30)
- Effects of anthocyanins on the AhR-CYP1A1 signaling pathway in human hepatocytes and human cancer cell lines. (2013) (30)
- The p38 MAPK inhibitor SB203580 induces cytochrome P450 1A1 gene expression in murine and human hepatoma cell lines through ligand-dependent aryl hydrocarbon receptor activation. (2011) (29)
- Estrogenic Activity Measurements in Water Using Diffusive Gradients in Thin-Film Coupled with an Estrogen Bioassay. (2017) (29)
- Enantiospecific Effects of Ketoconazole on Aryl Hydrocarbon Receptor (2014) (29)
- Aryl hydrocarbon receptor-mediated activity of particulate organic matter from the Paso del Norte airshed along the U.S.-Mexico border. (2003) (28)
- Interaction of diuron and related substituted phenylureas with the Ah receptor pathway (2006) (28)
- Deciphering Dimerization Modes of PAS Domains: Computational and Experimental Analyses of the AhR:ARNT Complex Reveal New Insights Into the Mechanisms of AhR Transformation (2016) (28)
- Mechanism-based common reactivity pattern (COREPA) modelling of aryl hydrocarbon receptor binding affinity (2010) (27)
- The hepatic Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin: species differences in subunit dissociation. (1990) (27)
- Modulation of CYP1A expression in rainbow trout by a technical grade formulation of propiconazole (1999) (26)
- Common Commercial and Consumer Products Contain Activators of the Aryl Hydrocarbon (Dioxin) Receptor (2013) (26)
- CALUX measurements: statistical inferences for the dose-response curve. (2011) (25)
- Application of the luciferase recombinant cell culture bioassay system for the analysis of polycyclic aromatic hydrocarbons (2002) (25)
- Transcriptional and posttranslational inhibition of dioxin-mediated induction of CYP1A1 by harmine and harmol. (2012) (25)
- In situ measurement of estrogenic activity in various aquatic systems using organic diffusive gradients in thin-film coupled with ERE-CALUX bioassay. (2019) (25)
- Structure and function of the Ah receptor: sulfhydryl groups required for binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin to cytosolic receptor from rodent livers. (1987) (24)
- Determination of in vitro relative potency (REP) values for mono-ortho polychlorinated biphenyls after purification with active charcoal. (2006) (24)
- Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanisms. (2014) (24)
- Brevetoxin-6 (PbTx-6), a nonaromatic marine neurotoxin, is a ligand of the aryl hydrocarbon receptor. (1997) (24)
- Microsomal Aryl Hydrocarbon Hydroxylase Comparison of the Direct, Indirect and Radiometric Assays (1983) (24)
- In Vitro Evaluation of Mitochondrial Function and Estrogen Signaling in Cell Lines Exposed to the Antiseptic Cetylpyridinium Chloride (2017) (23)
- DNA binding of the transformed guinea pig hepatic Ah receptor complex: identification and partial characterization of two high-affinity DNA-binding forms. (1995) (23)
- Comparative In Vitro and In Silico Analysis of the Selectivity of Indirubin as a Human Ah Receptor Agonist (2018) (23)
- Production of novel recombinant cell line bioassay systems for detection of 2,3,7,8-tetrachlorodibenzo-p-dioxin-like chemicals. (1993) (22)
- 2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced MUC5AC expression: aryl hydrocarbon receptor-independent/EGFR/ERK/p38-dependent SP1-based transcription. (2011) (22)
- Characterisation and implementation of the ERE-CALUX bioassay on indoor dust samples of kindergartens to assess estrogenic potencies (2016) (22)
- Environmental Estrogens in Agricultural Drain Water from the Central Valley of California (1998) (21)
- Development of a recombinant human ovarian (BG1) cell line containing estrogen receptor α and β for improved detection of estrogenic/antiestrogenic chemicals (2016) (21)
- Persistent vitellogenin-like protein and binding of DDT in the serum of insecticide-resistant mosquitofish (Gambusia affinis). (1981) (21)
- PCBs contamination in seafood species at the Eastern Coast of Thailand. (2009) (21)
- Specific ligand binding domain residues confer low dioxin responsiveness to AHR1β of Xenopus laevis. (2013) (21)
- Induction of hepatic cytochrome P450 gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin. (1989) (20)
- Analysis of dioxins in contaminated soils with the CALUX and CAFLUX bioassays, an immunoassay, and gas chromatography/high‐resolution mass spectrometry (2007) (20)
- Reduction of vitellogenin synthesis by an aryl hydrocarbon receptor agonist in the white sturgeon (Acipenser Transmontamus) (2009) (20)
- Induction of Cyp 1 a 1 Is a Nonspecific Biomarker of Aryl Hydrocarbon Receptor Activation : Results of Large Scale Screening of Pharmaceuticals and Toxicants in Vivo and in Vitro (2007) (19)
- Micronucleus formation by single and mixed heavy metals/loids and PAH compounds in HepG2 cells. (2015) (19)
- Protamine sulfate precipitation: a new assay for the Ah receptor. (1984) (19)
- Naturally occurring marine brominated indoles are aryl hydrocarbon receptor ligands/agonists. (2015) (19)
- METHYLATED PAHS AND/OR THEIR METABOLITES ARE IMPORTANT CONTRIBUTORS TO THE OVERALL ESTROGENIC ACTIVITY OF PAH-CONTAMINATED SOILS (2017) (19)
- Effect of in utero and postnatal exposure to environmental tobacco smoke on the developmental expression of pulmonary cytochrome P450 monooxygenases (2000) (18)
- Mouse breast cancer model-dependent changes in metabolic syndrome-associated phenotypes caused by maternal dioxin exposure and dietary fat. (2009) (18)
- Effect based monitoring of seasonal ambient air exposures in Australia sampled by PUF passive air samplers. (2010) (18)
- Development of an integrated approach for comparison of in vitro and in vivo responses to particulate matter (2015) (18)
- Structural modeling of the AhR:ARNT complex in the bHLH-PASA-PASB region elucidates the key determinants of dimerization. (2017) (17)
- The Ah receptor can bind ligand in the absence of receptor-associated heat-shock protein 90. (1998) (17)
- Activation of the aryl hydrocarbon receptor by the widely used Src family kinase inhibitor 4-amino-5-(4-chlorophenyl)-7-(dimethylethyl)pyrazolo[3,4-d]pyrimidine (PP2) (2015) (17)
- Synthesis and estrogen receptor affinity of a 4-hydroxytamoxifen-labeled ligand for diagnostic imaging. (2002) (17)
- 2,3-cis-2R,3R-(−)-epiafzelechin-3-O-p-coumarate, a novel flavan-3-ol isolated from Fallopia convolvulus seed, is an estrogen receptor agonist in human cell lines (2013) (16)
- DNA Binding (Gel Retardation Assay) Analysis for Identification of Aryl Hydrocarbon (Ah) Receptor Agonists and Antagonists (2014) (16)
- Assessing the receptor-mediated activity of PAHs using AhR-, ERα- and PPARγ- CALUX bioassays. (2020) (16)
- Analysis of PCDD/Fs and dioxin-like PCBs in atmospheric deposition samples from the Flemish measurement network: Optimization and validation of a new CALUX bioassay method. (2011) (16)
- The CALUX bio-assay: analytical comparison between mouse hepatoma cell lines with a low (H1L6.1c3) and high (H1L7.5c1) number of dioxin response elements. (2011) (16)
- Application of the CALUX (chemical activated luciferase gene expression) assay for measuring TCDD-equivalents in sediment, pore water and blood plasma samples. (1996) (16)
- Dioxins, furans and dioxin-like PCBs in sediment samples and suspended particulate matter from the Scheldt estuary and the North Sea Coast: Comparison of CALUX concentration levels in historical and recent samples. (2018) (15)
- Mathematical model developed for environmental samples: prediction of GC/MS dioxin TEQ from XDS-CALUX bioassay data. (2007) (15)
- Relationship between the molecular composition, visible light absorption, and health-related properties of smoldering woodsmoke aerosols (2019) (15)
- Dietary red clover (Trifolium pratense) induces oviduct growth and decreases ovary and testes growth in Japanese quail chicks. (2009) (15)
- Application of the luciferase cell culture bioassay for the detection of refined petroleum products. (2002) (14)
- Toxicant-Receptor Interactions : Modulations of signal transduction and gene expression (1998) (14)
- Ginsenosides Are Novel Naturally-Occurring Aryl Hydrocarbon Receptor Ligands (2013) (14)
- Novel 2-amino-isoflavones exhibit aryl hydrocarbon receptor agonist or antagonist activity in a species/cell-specific context. (2012) (14)
- Nucleotide specificity of DNA binding of the aryl hydrocarbon receptor:ARNT complex is unaffected by ligand structure. (2014) (14)
- Vemurafenib acts as an aryl hydrocarbon receptor antagonist: Implications for inflammatory cutaneous adverse events (2019) (14)
- Quantification of PCDD/Fs and dioxin-like PCBs in small amounts of human serum using the sensitive H1L7.5c1 mouse hepatoma cell line: optimization and analysis of human serum samples from adolescents of the Flemish human biomonitoring program FLEHS II. (2011) (13)
- Assessing indoor air exposures using passive sampling with bioanalytical methods for estrogenicity and aryl hydrocarbon receptor activity (2009) (13)
- Endocrine activity in an urban river system and the biodegradation of estrogen-like endocrine disrupting chemicals through a bio-analytical approach using DRE- and ERE-CALUX bioassays. (2018) (12)
- Species-specific antagonism of Ah receptor action by 2,2',5,5'-tetrachlorobiphenyl. (1993) (12)
- Analysis of PCDD/Fs and dioxin-like PCBs in atmospheric deposition samples from the Flemish measurement network: correlation between the CALUX bioassay and GC-HRMS. (2012) (12)
- In vitro and in silico derived relative effect potencies of ah-receptor-mediated effects by PCDD/Fs and PCBs in rat, mouse, and guinea pig CALUX cell lines. (2014) (12)
- The molecular mechanism of action of 2,3,7,8-tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons (1991) (12)
- Elimination of interfering compounds in preparation for analysis by an Ah receptor based bioassay (2002) (12)
- An Aryl Hydrocarbon Receptor from the Salamander Ambystoma mexicanum Exhibits Low Sensitivity to 2,3,7,8-Tetrachlorodibenzo-p-dioxin. (2015) (12)
- Transitional States in Ligand-Dependent Transformation of the Aryl Hydrocarbon Receptor into Its DNA-Binding Form (2020) (12)
- Comparative studies on the effects of green tea extracts and individual tea catechins on human CYP 1 A gene expression (2000) (11)
- A biomimetic, one-step transformation of simple indolic compounds to Malassezia-related alkaloids with high AhR potency and efficacy. (2019) (11)
- Time-integrated monitoring of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/Fs) in urban and industrial wastewaters using a ceramic toximeter and the CALUX bioassay. (2014) (11)
- Methylated polycyclic aromatic hydrocarbons and/or their metabolites are important contributors to the overall estrogenic activity of polycyclic aromatic hydrocarbon–contaminated soils (2018) (10)
- Regulation of cytochrome P1-450 gene expression in mouse hepatoma cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin. (1989) (10)
- Effect of benzene and ethylbenzene on the transcription of methyl-tert-butyl ether degradation genes of Methylibium petroleiphilum PM1. (2016) (10)
- Identification of the Herbicide Surflan and Its Active Ingredient Oryzalin, a Dinitrosulfonamide, as Xenoestrogens (2005) (10)
- Differential gene expression in wild-type and arnt-defective mouse hepatoma (Hepa1c1c7) cells. (1999) (10)
- Down-regulation of cytochrome P450 1A1 by monomethylarsonous acid in human HepG2 cells. (2017) (10)
- Assessment of estrogenic compounds in paperboard for dry food packaging with the ERE-CALUX bioassay. (2019) (10)
- Lack of ligand-selective binding of the aryl hydrocarbon receptor to putative DNA binding sites regulating expression of Bax and paraoxonase 1 genes. (2014) (9)
- Rapid extraction of total lipids and lipophilic POPs from all EU-regulated foods of animal origin: Smedes’ method revisited and enhanced (2020) (9)
- Recovery determinations for bioassay analysis : Considerations and results (2002) (9)
- Heterogeneity of rat hepatic Ah receptor: identification of two receptor forms which differ in their biochemical properties. (1992) (9)
- Detection of Estrogen Receptor Endocrine Disruptor Potency of Commonly Used Organochlorine Pesticides Using The LUMI-CELL ER Bioassay (2004) (9)
- REVISED EU-CRITERIA FOR APPLYING BIOANALYTICAL METHODS FOR SCREENING OF FEED AND FOOD FOR DIOXINS AND DIOXIN-LIKE PCBS. (2010) (9)
- Dioxin analysis in water by using a passive sampler and CALUX bioassay. (2012) (9)
- Reversible stepwise negative regulation of CYP1A1 in cultured rat epidermal cells. (2003) (8)
- Cell-based assays for identification of aryl hydrocarbon receptor (AhR) activators (2014) (8)
- Assessment of estrogenic and androgenic activity in PM10 air samples from an urban, industrial and rural area in Flanders (Belgium) using the CALUX bioassay. (2016) (8)
- Detection of xenoestrogens in serum after immunoprecipitation of endogenous steroidal estrogens. (2002) (8)
- Assessment of dioxin-like activity in PM10 air samples from an industrial location in Algeria, using the DRE-CALUX bioassay (2017) (8)
- Gene mdpC plays a regulatory role in the methyl-tert-butyl ether degradation pathway of Methylibium petroleiphilum strain PM1. (2015) (8)
- Species-specific differences in Ah receptor ligand binding and transcriptional activation: implications for bioassays for the detection of dioxin-like chemicals. (1995) (8)
- Nuclear Ah receptor from mouse hepatoma cells: effect of partial proteolysis on relative molecular mass and DNA-binding properties. (1990) (8)
- Assessing the biological reactivity of organic compounds on volcanic ash: implications for human health hazard (2021) (8)
- Using Estrogenic Activity and Nontargeted Chemical Analysis to Identify Contaminants in Sewage Sludge. (2021) (8)
- Changes in Menidia beryllina Gene Expression and In Vitro Hormone-Receptor Activation After Exposure to Estuarine Waters Near Treated Wastewater Outfalls (2016) (8)
- Assessment of estrogenic activity in PM₁₀ air samples with the ERE-CALUX bioassay: Method optimization and implementation at an urban location in Flanders (Belgium). (2016) (7)
- High throughput in vitro and in vivo screening of inland waters of Southern California. (2017) (7)
- Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in rat liver: lack of sensitivity to alkaline phosphatase when compared with that of glucocorticoid receptor. (1989) (7)
- Rapid bioassay for the determination of dioxins and dioxin-like PCDFs and PCBs in meat and animal feeds. (2005) (7)
- Correlation between the high expression of C/EBPβ protein in F442A cells and their relative resistance to antiadipogenic action of TCDD in comparison to 3T3‐L1 cells (2002) (7)
- Use of nuclear receptor luciferase-based bioassays to detect endocrine active chemicals in a biosolids-biochar amended soil. (2017) (6)
- Identifying Toxicologically Significant Compounds in Urban Wildfire Ash Using In Vitro Bioassays and High-Resolution Mass Spectrometry. (2021) (6)
- The Cellular and Molecular Determinants of Naphthoquinone-Dependent Activation of the Aryl Hydrocarbon Receptor (2020) (5)
- Time-integrated monitoring of dioxin-like polychlorinated biphenyls (dl-PCBs) in aquatic environments using the ceramic toximeter and the CALUX bioassay. (2014) (5)
- Auto-induction mechanism of aryl hydrocarbon receptor 2 (AHR2) gene by TCDD-activated AHR1 and AHR2 in the red seabream (Pagrus major) (2016) (5)
- Specificity of nuclear protein binding to a CYP1A1 negative regulatory element. (2002) (5)
- Recombinant cell lines for the detection of dioxins and Ah receptor ligands : Not all assays are created equal (2002) (5)
- Persistent Organic Pollutants (POPs) and Immune Function in US Atlantic Coast Harbor Seals (Phoca vitulina concolor ) (2003) (5)
- A green fluorescent protein based recombinant cell bioassay for the detection of activators of the aryl hydrocarbon receptor : Application for screening of a 1,5-dialkylamino-2,4-dinitrobenzene combinatorial chemical library (2000) (4)
- Characterization of hsp90‐binding to the the PASB domain of the Ah receptor (2006) (4)
- Activation of AH and estrogen receptor-based cell bioassay systems by extracts of natural dietary herbal supplements (2000) (4)
- Assessing the estrogenic activity of chemicals present in resin based dental composites and in leachates of commercially available composites using the ERα-CALUX bioassay. (2021) (4)
- Mechanism based common reactivity pattern (COREPA) modeling of AhR binding affinity (2010) (4)
- Ah RECEPTOR-BASED BIOASSAYS FOR DIOXINS AND RELATED CHEMICALS: APPLICATIONS AND LIMITATIONS. (1999) (3)
- DISCREPANCIES BETWEEN BIO-ANALYTICAL AND CHEMO-ANALYTICAL RESULTS HAVE A NON-NEGLIGIBLE MESSAGE (2010) (3)
- Surrogates for dioxin analyses : Analytical, elisa and toxicological aspects (2000) (3)
- Evaluation of the dioxin-like toxicity in soil samples from Thua Thien Hue province using the AhR-CALUX bioassay - An update of Agent Orange contamination in Vietnam. (2021) (3)
- Antagonistic effects of diortho PCBs (PCB 52 and 128) on Ah receptor-mediated induction of luciferase activity by 3,3',4,4'-tetrachlorobiphenyl (PCB 77) in mouse Hepa-1c1c7 cells. (1993) (3)
- Development of a novel recombinant cell line for detection and characterization of Ah receptor nuclear translocation in intact cells. (2020) (3)
- Binding of insecticides to serum proteins in mosquitofish (Gambusia affinis). (1985) (2)
- Bioanalytical approaches for the detection of dioxin and related halogenated aromatic hydrocarbons (2002) (2)
- Short-term interactions between DDT and endrin accumulation and elimination in mosquitofish (Gambusia affinis) (1985) (2)
- DNA sequence-specific binding of transformed Ah receptor to a dioxin responsive enhancer : looks Aren't everything (1992) (2)
- Toxic Equivalency Factors for Dioxins and Dioxin-like Compounds 2 3 (2006) (2)
- Synergistic activation of ah receptor-dependent gene expression by activators of protein kinase C (2000) (2)
- Tryptophan metabolites, indole-3-pyruvic acid, DL-3- indolelactic acid, L-kynurenine, and kynurenic acid activate ah receptor signal transduction (2000) (2)
- Rosmarinus officinalis L. Leaf Extracts and Their Metabolites Inhibit the Aryl Hydrocarbon Receptor (AhR) Activation In Vitro and in Human Keratinocytes: Potential Impact on Inflammatory Skin Diseases and Skin Cancer (2022) (2)
- Analysis of PCDD/Fs and dioxin-like PCBs in sewage sludges and general bio-wastes available for agricultural land application in Belgium - comparison between GC-IDHRMS and CALUX results (2012) (2)
- Induction of hepatic microsomal cytochrome P-450 and associated monooxygenases by pentamethylbenzene in the rat. (1983) (2)
- Ah receptor mediated effects of particulate organic extracts from the Paso del Norte airshed along the U.S. - Mexico border (2000) (2)
- SMRT mediated transcriptional silencing of the AH receptor signaling pathway not observed in human MCF-7 or BG-1 cell lines (2000) (2)
- NEW CUT-OFF VALUES FOR APPLICATIONS IN BIOANALYTICAL SCREENING: DECISION OVER SAMPLE COMPLIANCE WITH LEGAL LIMITS SET BY THE EUROPEAN UNION FOR PCDD/Fs AND DIOXIN-LIKE PCBs (2010) (2)
- Nickel and nickel-conjugate metabolism and acute toxicity. (1989) (1)
- 1057 Vemurafenib acts as an aryl hydrocarbon receptor antagonist (2018) (1)
- VALIDATION OF THE LUMI-CELL™ ER RECOMBINANT BIOASSAY FOR RAPID EVALUATION OF CHEMICALS FOR POTENTIAL ESTROGENIC ACTIVITY (2003) (1)
- Woodsmoke Extracts Cross-Link Proteins and Induce Cornified Envelope Formation without Stimulating Keratinocyte Terminal Differentiation. (2021) (1)
- Correlation between the high expression of C/EBPbeta protein in F442A cells and their relative resistance to antiadipogenic action of TCDD in comparison to 3T3-L1 cells. (2002) (1)
- Identification and characterization of novel flavone agonists of the Ah receptor (2003) (1)
- onsiderations for potency equivalent calculations in the Ah receptor-based ALUX bioassay : Normalization of superinduction results for improved sample otency estimation avid (2010) (1)
- Editorial overview: The aryl hydrocarbon (Ah) receptor: From toxicology to human health (2017) (1)
- LUMI-CELL™ ER, A RECOMBINANT BIOASSAY FOR RAPID EVALUATION OF POTENTIAL ESTROGENIC ENDOCRINE DISRUPTOR CHEMICALS (2004) (1)
- Screening for aryl hydrocarbon receptor activity in ambient air using passive sampling (SPMDS) and CAFLUX (2007) (1)
- New insights into the structure of the mahr ligand binding domain (2002) (1)
- Synthesis of a ligand–quencher conjugate for the ligand binding study of the aryl hydrocarbon receptor using a FRET assay (2012) (1)
- Application of a human ovarian cell bioassay for the detection and analysis of estrogen-toxicant interactions (2000) (1)
- Validation of a cell culture bioassay for detection of petroleum exposure in mink (Mustela vison) as a model for detection in sea otters (Enhydra lutris). (2002) (1)
- Progressive silencing of CYP1A1 induction in rat keratinocytes (2000) (1)
- Testing structure-binding predictions from comparative modeling of the AHR ligand-binding domain: Studies with zebrafish AHR1a (2011) (1)
- Revealed by Site-Directed Mutagenesis Receptor Agonists and Antagonists Ligand Promiscuity of Aryl Hydrocarbon (2014) (1)
- An Aryl Hydrocarbon Receptor from the Caecilian Gymnopis multiplicata Suggests Low Dioxin Affinity in the Ancestor of All Three Amphibian Orders (2019) (1)
- Do PCDD/PCDF standard solutions used in dioxin analysis pose a risk as potentially acutely toxic to lab personnel? (2017) (1)
- Myeloperoxidase-Dependent Nitration and Oxidation ofp-Cresol: A Novel Pathway for Xenobiotic Metabolism. (2009) (0)
- Activation of the ah receptor and ah receptor signal transduction pathway by tryptophan-derived agonists (2003) (0)
- Neonicotinoids induce a promoter-switchin CYP19 expression in breast-cancer cells and alter aromatase activity and hormoneproduction in a feto-placental co-culture model (2016) (0)
- Extraction and bioanalysis of arylhydrocarbon- and estrogen- receptor active compounds (1997) (0)
- Physiocochemical characterization of the cytosolic Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) (1985) (0)
- PROCESS OF VALIDATION OF THE LUMI-CELL™ ER RECOMBINANT BIOASSAY FOR RAPID EVALUATION OF POTENTIAL ESTROGENIC ENDOCRINE DISRUPTOR CHEMICALS (2004) (0)
- Brussel Endocrine activity in waste and river waters from the Brussels Region , Belgium using the BG 1 Luc 4 E 2 CALUX Bioassay (2018) (0)
- CHARACTERIZATION OF THE CALUX AND GRAB BIOASSAYS FOR SENSITIVITY AND SPECIFICITY IN DETECTION OF PHARMACOLOGICAL AGENTS THAT ACTIVATE THE Ah RECEPTOR SIGNALING SYSTEM (2007) (0)
- Sustained activation of the Aryl hydrocarbon Receptor transcription factor promotes resistance to BRAF-inhibitors in melanoma (2018) (0)
- Combined genotoxic effect of arsenic, cadmium, chromium and four polyaromatic hydrocarbons (2015) (0)
- Archives of Biochemistry and Biophysics (2015) (0)
- Auto-induction mechanism of aryl hydrocarbon receptor 2 (AHR2) gene by TCDD-activated AHR1 and AHR2 in the red seabream (Pagrus major) (2016) (0)
- An Aryl Hydrocarbon Receptor Sequence from the Caecilian Gymnopis multiplicata Exhibits Low Responsiveness to 2,3,7,8-tetrachlorodibenzo-p-dioxin (2018) (0)
- Activation of the aryl hydrocarbon receptor by the widely used Src family kinase inhibitor 4-amino-5-(4-chlorophenyl)-7-(dimethylethyl)pyrazolo[3,4-d]pyrimidine (PP2) (2014) (0)
- Molecular characterization of the Ah-receptor pathway in flounder (Platichtys flesus). (1998) (0)
- Screening and analysis of novel naphthoflavone ligands for the Ah receptor (2003) (0)
- UC Office of the President Recent Work Title Sustained activation of the Aryl hydrocarbon Receptor transcription factor promotes resistance to BRAF-inhibitors in melanoma Permalink (2018) (0)
- States in Ligand-Dependent Transformation of the Aryl Receptor into Its DNA-Binding Form. (2020) (0)
- Bioanalytical screening of low levels of dioxins and dioxin-like PCBs in pig meat (pork) for checking compliance with EU maximum and action levels using highly sensitive “third generation” recombinant H4L7.5c2 rat hepatoma cells (2021) (0)
- Analysis of Soil Samples from a Hazardous Waste Site : Comparison of CALUX ® Bioassay TEQ Determinations with High Resolution GC / MS (2002) (0)
- Determination of Androgenic activity on a stably transfected human breast cell line (2006) (0)
- A model for functional analyses of coadaptor involvement in dioxin-inducible gene expression (2000) (0)
- Growth regulation by ahr ligands in the human mammary epithelial cell line MCF-10A (2000) (0)
- Easy transformation of indoles to substituted tryptanthrins with powerful AHR activity (2012) (0)
- Isolation of malassezia metabolites with powerful AHR activity from human skin. is there implication in skin cancer development (2012) (0)
- Molecular Mechanism of Dioxin Action: Molecular Cloning of the Ah Receptor Using a DNA Recognition Site Probe (1992) (0)
- Binding specificity of diverse AhR ligands interpreted by Molecular Modeling (2016) (0)
- Role of chelatable metal ions in aryl hydorcarbon receptor (AhR) function (2000) (0)
- Modeling the binding of diverse ligands within the Ah receptor ligand binding domain (2019) (0)
- 22nd International Symposium on Environmental Halogenated Organic Pollutants and POPs Barcelona, Spain, August 12–16, 2002 (2002) (0)
- Brussel In vitro reporter gene activity of PCDD / Fs and dl-PCBs in wood ash from domestic heating systems ( Belgium ) using the H 1 L 7 . 5 c 1 CALUX Bioassay (2018) (0)
- Deciphering the ahr:arnt dimerization process: how to assembly the functional puzzle of interacting interfaces (2016) (0)
- Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): Subunit dissociation and inactivation of ligand binding in conditions of high ionic strength (1985) (0)
- Identification of novel agonists and antagonists of the Ah receptor signal transduction pathway (2003) (0)
- Polyoxymethylene (POM) is a suitable tool for 1 effect-based hazard 2 assessment of PAC-contaminated soil (2018) (0)
- Dioxin exposure and effects assessment of red-tailed tropicbirds nesting on Johnston Island, central pacific ocean (2000) (0)
- Synthesis of a ligand–quencher conjugate for the ligand binding study of the aryl hydrocarbon receptor using a FRET assay (2011) (0)
- Brevetoxin: Biotransformation and effects on xenobiotic metabolizing enzymes (1996) (0)
- Specific amino acid residues within the ligand binding domain confer low responsiveness to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) to an aryl hydrocarbon receptor (AHR) from the frog Xenopus Laevis (2011) (0)
- FACTOR-Receptor and the Inflammatory Response : Cross-talk between Aryl Hydrocarbon Gene Regulation : (2014) (0)
- Ontogeny of the cytosolic TCDD receptor in the chick embryo and neonate (1984) (0)
- Boitano Human Hematopoietic Stem Cells Aryl Hydrocarbon Receptor Antagonists Promote the Expansion of (2012) (0)
- Development of an integrated approach for comparison of in vitro and in vivo responses to particulate matter (2015) (0)
- NF-κB is involved in cross-talk between ah-receptor and signal transduction pathways (2002) (0)
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What Schools Are Affiliated With Michael Steven Denison?
Michael Steven Denison is affiliated with the following schools: