Michael Sendtner
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Computer Science
Michael Sendtner's Degrees
- Masters Computer Science Stanford University
- Bachelors Computer Science University of California, Berkeley
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(Suggest an Edit or Addition)Michael Sendtner's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD (2011) (3746)
- Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study (2012) (1007)
- Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy (1990) (844)
- Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 (2021) (811)
- The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn(-/-) mice and results in a mouse with spinal muscular atrophy. (2000) (731)
- Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section (1992) (712)
- Inactivation of the survival motor neuron gene, a candidate gene for human spinal muscular atrophy, leads to massive cell death in early mouse embryos. (1997) (648)
- The Notch target genes Hey1 and Hey2 are required for embryonic vascular development. (2004) (648)
- Smn, the spinal muscular atrophy–determining gene product, modulates axon growth and localization of β-actin mRNA in growth cones of motoneurons (2003) (642)
- Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor (1989) (622)
- Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: comparison with other neurotrophic factors and cytokines (1990) (594)
- Disruption of the CNTF gene results in motor neuron degeneration (1993) (579)
- Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis (2011) (569)
- Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy (1992) (560)
- Na+-d-glucose Cotransporter SGLT1 is Pivotal for Intestinal Glucose Absorption and Glucose-Dependent Incretin Secretion (2011) (545)
- Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis (2016) (424)
- Gene disruption discloses role of selenoprotein P in selenium delivery to target tissues. (2003) (406)
- Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis (2014) (404)
- CNTF is a major protective factor in demyelinating CNS disease: A neurotrophic cytokine as modulator in neuroinflammation (2002) (400)
- Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration (1992) (372)
- Regional distribution, developmental changes, and cellular localization of CNTF-mRNA and protein in the rat brain (1991) (352)
- Evidence that Embryonic Neurons Regulate the Onset of Cortical Gliogenesis via Cardiotrophin-1 (2005) (350)
- Ciliary neurotrophic factor induces cholinergic differentiation of rat sympathetic neurons in culture (1989) (343)
- Ciliary neurotrophic factor induces type-2 astrocyte differentiation in culture (1988) (332)
- Essential function of LIF receptor in motor neurons (1995) (327)
- Developmental Requirement of gp130 Signaling in Neuronal Survival and Astrocyte Differentiation (1999) (325)
- Mutations in the gene encoding immunoglobulin μ-binding protein 2 cause spinal muscular atrophy with respiratory distress type 1 (2001) (311)
- Neurotrophins: from enthusiastic expectations through sobering experiences to rational therapeutic approaches (2002) (311)
- Specific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: a role for Smn in RNA processing in motor axons? (2002) (311)
- Proliferation and differentiation of embryonic chick sympathetic neurons: Effects of ciliary neurotrophic factor (1989) (296)
- Inactivation of bcl-2 Results in Progressive Degeneration of Motoneurons, Sympathetic and Sensory Neurons during Early Postnatal Development (1996) (283)
- Does oligodendrocyte survival depend on axons? (1993) (280)
- Global Deprivation of Brain-Derived Neurotrophic Factor in the CNS Reveals an Area-Specific Requirement for Dendritic Growth (2010) (275)
- Members of several gene families influence survival of rat motoneurons in vitro and in vivo (1993) (270)
- A phase I/II trial of recombinant methionyl human brain derived neurotrophic factor administered by intrathecal infusion to patients with amyotrophic lateral sclerosis (2000) (269)
- Can physical exercise in old age improve memory and hippocampal function? (2016) (246)
- Type-2 astrocyte development in rat brain cultures is initiated by a CNTF like protein produced by type-1 astrocytes (1988) (240)
- Intraocular Gene Transfer of Ciliary Neurotrophic Factor Prevents Death and Increases Responsiveness of Rod Photoreceptors in theretinal degeneration slow mouse (1998) (234)
- Relationships of peripheral IGF-1, VEGF and BDNF levels to exercise-related changes in memory, hippocampal perfusion and volumes in older adults (2016) (229)
- Ciliary neurotrophic factor. (1994) (206)
- NEK1 variants confer susceptibility to amyotrophic lateral sclerosis (2016) (195)
- Conditional gene ablation of Stat3 reveals differential signaling requirements for survival of motoneurons during development and after nerve injury in the adult (2002) (195)
- ras p21 protein promotes survival and fiber outgrowth of cultured embryonic neurons (1989) (193)
- Expression of neurotrophins in skeletal muscle: Quantitative comparison and significance for motoneuron survival and maintenance of function (1995) (192)
- Clinical characteristics of patients with familial amyotrophic lateral sclerosis carrying the pathogenic GGGGCC hexanucleotide repeat expansion of C9ORF72. (2012) (191)
- Functional role of brain-derived neurotrophic factor in neuroprotective autoimmunity: therapeutic implications in a model of multiple sclerosis. (2010) (187)
- Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease. (2011) (182)
- Reduced survival motor neuron (Smn) gene dose in mice leads to motor neuron degeneration: an animal model for spinal muscular atrophy type III. (2000) (180)
- Adenoviral gene transfer of ciliary neurotrophic factor and brain-derived neurotrophic factor leads to long-term survival of axotomized motor neurons (1997) (172)
- Ciliary neurotrophic factor: Pharmacokinetics and acute‐phase response in rat (1994) (168)
- Cryptic physiological trophic support of motoneurons by LIF revealed by double gene targeting of CNTF and LIF (1996) (168)
- Muscle-derived factors that support survival and promote fiber outgrowth from embryonic chick spinal motor neurons in culture. (1986) (159)
- Ciliary Neurotrophic Factor Enhances the Rate of Oligodendrocyte Generation (1996) (159)
- Ribosomal deficiencies in Diamond-Blackfan anemia impair translation of transcripts essential for differentiation of murine and human erythroblasts. (2012) (157)
- Reg-2 is a motoneuron neurotrophic factor and a signalling intermediate in the CNTF survival pathway (2000) (157)
- Defective Ca2+ channel clustering in axon terminals disturbs excitability in motoneurons in spinal muscular atrophy (2007) (156)
- Extracellular matrix-associated molecules collaborate with ciliary neurotrophic factor to induce type-2 astrocyte development (1990) (151)
- The CB1 Cannabinoid Receptor Mediates Excitotoxicity-induced Neural Progenitor Proliferation and Neurogenesis* (2007) (148)
- Developmental motoneuron cell death and neurotrophic factors (2000) (144)
- A transgene carrying an A2G missense mutation in the SMN gene modulates phenotypic severity in mice with severe (type I) spinal muscular atrophy (2003) (141)
- Cardiotrophin-1, a Muscle-Derived Cytokine, Is Required for the Survival of Subpopulations of Developing Motoneurons (2001) (140)
- Evidence that fibroblast growth factor 5 is a major muscle-derived survival factor for cultured spinal motoneurons (1993) (136)
- Hot-spot KIF5A mutations cause familial ALS (2018) (136)
- Toxoplasma gondii in primary rat CNS cells: differential contribution of neurons, astrocytes, and microglial cells for the intracerebral development and stage differentiation. (1999) (135)
- Endogenous Ciliary Neurotrophic Factor Is a Lesion Factor for Axotomized Motoneurons in Adult Mice (1997) (133)
- A two-stage genome-wide association study of sporadic amyotrophic lateral sclerosis. (2009) (133)
- Bag1 is essential for differentiation and survival of hematopoietic and neuronal cells (2005) (130)
- PTEN depletion rescues axonal growth defect and improves survival in SMN-deficient motor neurons. (2010) (129)
- Effect of ciliary neurotrophic factor (CNTF) on motoneuron survival (1991) (123)
- C9ORF72 interaction with cofilin modulates actin dynamics in motor neurons (2016) (122)
- A genome-wide association meta-analysis identifies a novel locus at 17q11.2 associated with sporadic amyotrophic lateral sclerosis. (2014) (121)
- The role of p75NTR in modulating neurotrophin survival effects in developing motoneurons (1999) (119)
- Novel Role for Vascular Endothelial Growth Factor (VEGF) Receptor-1 and Its Ligand VEGF-B in Motor Neuron Degeneration (2008) (117)
- Missense mutation in the tubulin-specific chaperone E (Tbce) gene in the mouse mutant progressive motor neuronopathy, a model of human motoneuron disease (2002) (116)
- Early onset of severe familial amyotrophic lateral sclerosis with a SOD-1 mutation: potential impact of CNTF as a candidate modifier gene. (2002) (114)
- Adenosine receptor A2A-R contributes to motoneuron survival by transactivating the tyrosine kinase receptor TrkB (2007) (114)
- Genetic correlation between amyotrophic lateral sclerosis and schizophrenia (2017) (107)
- Specific function of B-Raf in mediating survival of embryonic motoneurons and sensory neurons (2001) (107)
- Isolation and enrichment of embryonic mouse motoneurons from the lumbar spinal cord of individual mouse embryos (2010) (107)
- Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology (2021) (104)
- Synaptic PRG-1 Modulates Excitatory Transmission via Lipid Phosphate-Mediated Signaling (2009) (103)
- Co-regulation of survival of motor neuron (SMN) protein and its interactor SIP1 during development and in spinal muscular atrophy. (2001) (102)
- Effect of Glutamate on Dendritic Growth in Embryonic Rat Motoneurons (1998) (102)
- Leukaemia inhibitory factor gene mutations in infertile women. (1999) (101)
- Hypomorphic Sox10 alleles reveal novel protein functions and unravel developmental differences in glial lineages (2007) (99)
- Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis (2019) (98)
- Association of a null mutation in the CNTF gene with early onset of multiple sclerosis. (2002) (96)
- Progressive Postnatal Motoneuron Loss in Mice Lacking GDF-15 (2009) (94)
- The CB1 cannabinoid receptor signals striatal neuroprotection via a PI3K/Akt/mTORC1/BDNF pathway (2015) (93)
- Neurotrophin Receptor-interacting Mage Homologue Is an Inducible Inhibitor of Apoptosis Protein-interacting Protein That Augments Cell Death* (2001) (92)
- Axonal defects in mouse models of motoneuron disease. (2004) (90)
- Characterization of Ighmbp2 in motor neurons and implications for the pathomechanism in a mouse model of human spinal muscular atrophy with respiratory distress type 1 (SMARD1). (2004) (87)
- Truncated TrkB receptor-induced outgrowth of dendritic filopodia involves the p75 neurotrophin receptor (2004) (86)
- Whole transcriptome profiling reveals the RNA content of motor axons (2015) (86)
- The heterogeneous nuclear ribonucleoprotein-R is necessary for axonal beta-actin mRNA translocation in spinal motor neurons. (2010) (85)
- Trophic Support of Motoneurons: Physiological, Pathophysiological, and Therapeutic Implications (1993) (84)
- The role of neurotrophins in muscle under physiological and pathological conditions (2006) (83)
- Subcellular transcriptome alterations in a cell culture model of spinal muscular atrophy point to widespread defects in axonal growth and presynaptic differentiation (2014) (82)
- Pharmacokinetics of Intrathecally Applied BDNF and Effects on Spinal Motoneurons (1996) (79)
- Distinct and overlapping alterations in motor and sensory neurons in a mouse model of spinal muscular atrophy. (2006) (78)
- EGF transactivation of Trk receptors regulates the migration of newborn cortical neurons (2013) (77)
- Gene targeting of Gemin2 in mice reveals a correlation between defects in the biogenesis of U snRNPs and motoneuron cell death (2002) (76)
- Neuromuscular defects and breathing disorders in a new mouse model of spinal muscular atrophy (2010) (76)
- The anti-apoptotic protein ITA is essential for NGF-mediated survival of embryonic chick neurons (1999) (73)
- The p75NTR-interacting protein SC1 inhibits cell cycle progression by transcriptional repression of cyclin E (2004) (73)
- SMN deficiency alters Nrxn2 expression and splicing in zebrafish and mouse models of spinal muscular atrophy. (2014) (71)
- Local axonal function of STAT3 rescues axon degeneration in the pmn model of motoneuron disease (2012) (69)
- Triple Knock-Out of CNTF, LIF, and CT-1 Defines Cooperative and Distinct Roles of these Neurotrophic Factors for Motoneuron Maintenance and Function (2005) (68)
- The neuronal apoptosis inhibitory protein suppresses neuronal differentiation and apoptosis in PC12 cells. (2000) (67)
- Neurotrophin receptors TrkB.T1 and p75NTR cooperate in modulating both functional and structural plasticity in mature hippocampal neurons (2010) (66)
- Actions of CNTF and neurotrophins on degenerating motoneurons: Preclinical studies and clinical implications (1994) (66)
- Comprehensive analysis of the mutation spectrum in 301 German ALS families (2018) (63)
- Presynaptic Localization of Smn and hnRNP R in Axon Terminals of Embryonic and Postnatal Mouse Motoneurons (2014) (61)
- Ciliary neurotrophic factor-induced sprouting preserves motor function in a mouse model of mild spinal muscular atrophy. (2010) (60)
- Hey bHLH factors in cardiovascular development. (2002) (60)
- Dynamic Changes in C-Raf Phosphorylation and 14-3-3 Protein Binding in Response to Growth Factor Stimulation (2004) (59)
- Microencapsulated Ciliary Neurotrophic Factor: Physical Properties and Biological Activities (1996) (58)
- Haploinsufficiency of c-Met in cd44−/− Mice Identifies a Collaboration of CD44 and c-Met In Vivo (2007) (58)
- Glycinergic and GABAergic Synaptic Activity Differentially Regulate Motoneuron Survival and Skeletal Muscle Innervation (2005) (58)
- C-terminal FUS/TLS mutations in familial and sporadic ALS in Germany (2011) (56)
- The role of SMN in spinal muscular atrophy (2000) (55)
- Plekhg5-regulated autophagy of synaptic vesicles reveals a pathogenic mechanism in motoneuron disease (2017) (54)
- The response of motoneurons to neurotrophins (1996) (52)
- Vascular Signal Transducer and Activator of Transcription-3 Promotes Angiogenesis and Neuroplasticity Long-Term After Stroke (2015) (51)
- Moving towards treatments for spinal muscular atrophy: hopes and limits (2015) (49)
- Molecular mechanisms in spinal muscular atrophy: models and perspectives (2001) (48)
- Deep Proteomic Evaluation of Primary and Cell Line Motoneuron Disease Models Delineates Major Differences in Neuronal Characteristics* (2014) (47)
- Laminin induced local axonal translation of β-actin mRNA is impaired in SMN-deficient motoneurons (2012) (46)
- Heterozygous Tbk1 loss has opposing effects in early and late stages of ALS in mice (2019) (45)
- Rat ciliary neurotrophic factor (CNTF): Gene structure and regulation of mRNA levels in glial cell cultures (1993) (43)
- Large-scale pathways-based association study in amyotrophic lateral sclerosis. (2007) (41)
- Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis (2020) (40)
- Role of Na(v)1.9 in activity-dependent axon growth in motoneurons. (2012) (40)
- Up-regulation of Ciliary Neurotrophic Factor in Astrocytes by Aspirin (2013) (39)
- Loss of Tdp-43 disrupts the axonal transcriptome of motoneurons accompanied by impaired axonal translation and mitochondria function (2020) (39)
- Potential role of LIF as a modifier gene in the pathogenesis of amyotrophic lateral sclerosis (2000) (38)
- Differential roles of α-, β-, and γ-actin in axon growth and collateral branch formation in motoneurons (2017) (37)
- Vascular Stat3 Promotes Angiogenesis and Neuroplasticity Long-Term After Stroke (2015) (37)
- Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGFδ/δ mouse model of amyotrophic lateral sclerosis (2010) (36)
- Mechanisms of axonal degeneration in EAE—lessons from CNTF and MHC I knockout mice (2005) (36)
- Single-dose application of CNTF and BDNF improves remyelination of regenerating nerve fibers after C7 ventral root avulsion and replantation. (2008) (34)
- Sox10 regulates ciliary neurotrophic factor gene expression in Schwann cells (2006) (33)
- In vivo adenoviral transduction of the neonatal rat cochlea and middle ear (2001) (33)
- Defective Ca 2 + channel clustering in axon terminals disturbs excitability in motoneurons in spinal muscular atrophy (2007) (33)
- Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma. (2018) (32)
- hnRNP R and its main interactor, the noncoding RNA 7SK, coregulate the axonal transcriptome of motoneurons (2018) (31)
- Insulin-like growth factor 1 in diabetic neuropathy and amyotrophic lateral sclerosis (2017) (31)
- Therapy development in spinal muscular atrophy (2010) (31)
- Neurodegenerative Disease: Oxidative stress and motorneuron disease (1994) (30)
- Fgfr2 and Fgfr3 are not required for patterning and maintenance of the midbrain and anterior hindbrain. (2007) (30)
- The FTLD Risk Factor TMEM106B Regulates the Transport of Lysosomes at the Axon Initial Segment of Motoneurons. (2020) (29)
- The CB 1 cannabinoid receptor signals striatal neuroprotection via a PI 3 K / Akt / mTORC 1 / BDNF pathway (2015) (28)
- Autophagy in the presynaptic compartment (2018) (28)
- Synaptic PRG-1 Modulates Excitatory Transmission via Lipid Phosphate-Mediated Signaling (2011) (28)
- Contribution of Ca(2+)-permeable AMPA/KA receptors to glutamate-induced Ca(2+) rise in embryonic lumbar motoneurons in situ. (2000) (28)
- Leukemia Inhibitory Factor Deficiency Modulates the Immune Response and Limits Autoimmune Demyelination: A New Role for Neurotrophic Cytokines in Neuroinflammation1 (2008) (27)
- Association of Variants in the SPTLC1 Gene With Juvenile Amyotrophic Lateral Sclerosis (2021) (27)
- Functional improvement in mouse models of familial amyotrophic lateral sclerosis by PEGylated insulin-like growth factor I treatment depends on disease severity (2012) (26)
- Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology (2021) (26)
- Developmental regulation of SMN expression: pathophysiological implications and perspectives for therapy development in spinal muscular atrophy (2017) (26)
- Neurotrophic factors: effects in modulating properties of the neuromuscular endplate. (1998) (26)
- Leukemia Inhibitory Factor Protects Axons in Experimental Autoimmune Encephalomyelitis via an Oligodendrocyte-Independent Mechanism (2012) (26)
- Therapeutic effects of PEGylated insulin-like growth factor I in the pmn mouse model of motoneuron disease (2011) (25)
- Exome array analysis of rare and low frequency variants in amyotrophic lateral sclerosis (2019) (25)
- Dysregulated IGFBP5 expression causes axon degeneration and motoneuron loss in diabetic neuropathy (2015) (24)
- Valproic acid blocks excitability in SMA type I mouse motor neurons (2009) (24)
- Gene therapy for motor neuron disease (1997) (24)
- Early onset of degenerative changes at nodes of Ranvier in alpha‐motor axons of Cntf null (−/−) mutant mice (2003) (23)
- Ciliary neurotrophic factor in the olfactory bulb of rats and mice (2003) (23)
- Stiff person syndrome associated anti-amphiphysin antibodies reduce GABA associated [Ca2+]i rise in embryonic motoneurons (2009) (23)
- The association between hypertensive arteriopathy and cerebral amyloid angiopathy in spontaneously hypertensive stroke‐prone rats (2018) (23)
- Neurotrophic Factors and Amyotrophic Lateral Sclerosis (1999) (22)
- Motoneuron cell death and neurotrophic factors: Basic models for development of new therapeutic strategies in ALS (2001) (22)
- Molecular biology of neurotrophic factors. (1995) (22)
- Endogenous Ciliary Neurotrophic Factor Protects GABAergic, But Not Cholinergic, Septohippocam pal Neurons Following Fimbria‐fornix Transection (2003) (22)
- Regulation of TrkB cell surface expression—a mechanism for modulation of neuronal responsiveness to brain-derived neurotrophic factor (2020) (22)
- Is activation of the Na+K+ pump necessary for NGF-mediated neuronal survival? (1988) (22)
- Molecular and cellular basis of spinal muscular atrophy (2003) (21)
- A genome-wide association meta-analysis identifies a novel locus at 17 q 11 . 2 associated with sporadic amyotrophic lateral sclerosis (2014) (21)
- Does the survival motor neuron protein (SMN) interact with Bcl-2? (2000) (21)
- Lectin-based Isolation and Culture of Mouse Embryonic Motoneurons (2011) (21)
- Cooperation of Tyrosine Kinase Receptor TrkB and Epidermal Growth Factor Receptor Signaling Enhances Migration and Dispersal of Lung Tumor Cells (2014) (21)
- Pathogenic inflammation in the CNS of mice carrying human PLP1 mutations. (2016) (21)
- Induction of BDNF Expression in Layer II/III and Layer V Neurons of the Motor Cortex Is Essential for Motor Learning (2020) (21)
- P90 Ribosomal s6 kinase 2 negatively regulates axon growth in motoneurons (2009) (20)
- High-efficiency gene transfer into cultured embryonic motoneurons using recombinant lentiviruses (2007) (20)
- Neurofilament depletion improves microtubule dynamics via modulation of Stat3/stathmin signaling (2016) (20)
- Effects of root replantation and neurotrophic factor treatment on long-term motoneuron survival and axonal regeneration after C7 spinal root avulsion (2005) (20)
- Motoneuron survival after C7 nerve root avulsion and replantation in the adult rabbit: effects of local ciliary neurotrophic factor and brain-derived neurotrophic factor application. (2005) (19)
- TDP-43: multiple targets, multiple disease mechanisms? (2011) (19)
- Potential implications of a ciliary neurotrophic factor gene mutation in a german population of patients with motor neuron disease (1998) (19)
- ALS‐Associated Endoplasmic Reticulum Proteins in Denervated Skeletal Muscle: Implications for Motor Neuron Disease Pathology (2017) (19)
- Ciliary neurotrophic factor (CNTF) protects retinal cone and rod photoreceptors by suppressing excessive formation of the visual pigments (2018) (19)
- Loss of Leukemia Inhibitory Factor Receptor β or Cardiotrophin-1 Causes Similar Deficits in Preganglionic Sympathetic Neurons and Adrenal Medulla (2006) (19)
- Comparative analysis of motoneuron loss and functional deficits in PMN mice: implications for human motoneuron disease (1999) (18)
- Thymocyte‐derived BDNF influences T‐cell maturation at the DN3/DN4 transition stage (2015) (18)
- Mechanisms for axon maintenance and plasticity in motoneurons: alterations in motoneuron disease (2014) (17)
- Ciliary neurotrophic factor-immunoreactivity in olfactory sensory neurons (2005) (16)
- The Gene for Ciliary Neurotrophic Factor (CNTF) Maps to Murine Chromosome 19 and its Expression is Not Affected in the Hereditary Motoneuron Disease ‘Wobbler’ of the Mouse (1991) (16)
- Interaction of 7SK with the Smn complex modulates snRNP production (2021) (15)
- Mechanical and excitotoxic lesion of motoneurons: effects of neurotrophins and ciliary neurotrophic factor on survival and regeneration. (1999) (14)
- Therapy development for spinal muscular atrophy: perspectives for muscular dystrophies and neurodegenerative disorders (2022) (14)
- Microtubule associated tumor suppressor 1 deficient mice develop spontaneous heart hypertrophy and SLE-like lymphoproliferative disease (2011) (14)
- Drosophila RSK negatively regulates bouton number at the neuromuscular junction (2009) (13)
- Signalling mechanisms for survival of lesioned motoneurons. (2004) (13)
- CNTF, STAT3 and new therapies for axonal degeneration: what are they and what can they do? (2013) (13)
- Stem cells: Tailor-made diseased neurons (2009) (13)
- Potential implications of a ciliary neurotrophic factor gene mutation in a German population of patients with motor neuron disease. (1998) (13)
- Spiral Ganglion Outgrowth and Hearing Development in p75NTR-Deficient Mice (2008) (12)
- Optical assessment of motoneuron function in a “twenty-four-hour” acute spinal cord slice model from fetal rats (2005) (12)
- Towards a comprehensive understanding of the trophic support of motoneurons. (1993) (12)
- Differential Modulation of Neurite Growth by the S- and the L-Forms of bag1, a Co-Chaperone of Hsp70 (2007) (12)
- Erratum: The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn-/- mice and results in a mouse with spinal muscular atrophy (Human Molecular Genetics (2000) vol. 9 (333-339)) (2007) (12)
- Motoneuron disease. (2014) (11)
- Overexpression of an ALS-associated FUS mutation in C. elegans disrupts NMJ morphology and leads to defective neuromuscular transmission (2020) (10)
- Analysis of European case-control studies suggests that common inherited variation in mitochondrial DNA is not involved in susceptibility to amyotrophic lateral sclerosis (2012) (10)
- Neurotrophic factors for experimental treatment of motoneuron disease. (1996) (9)
- DeepFLaSH, a deep learning pipeline for segmentation of fluorescent labels in microscopy images (2018) (8)
- Treatment with ciliary neurotrophic factor does not improve regeneration in experimental autoimmune neuritis of the Lewis rat (1996) (8)
- An essential role of the mouse synapse-associated protein Syap1 in circuits for spontaneous motor activity and rotarod balance (2019) (7)
- Development of a Fully Implantable Stimulator for Deep Brain Stimulation in Mice (2020) (6)
- Damaging secretions: chromogranins team up with mutant SOD1 (2006) (6)
- More on motor neurons (1992) (6)
- Network topology dynamics of circulating biomarkers and cognitive performance in older Cytomegalovirus-seropositive or -seronegative men and women (2019) (5)
- CDNF rescues motor neurons in three animal models of ALS by targeting ER stress (2020) (5)
- Overexpression of an ALS-associated FUS mutation in C. elegans disrupts NMJ morphology and leads to defective neuromuscular transmission. (2020) (5)
- A cholinergic neuroskeletal interface promotes bone formation during postnatal growth and exercise (2022) (5)
- Initial characterization of a Syap1 knock-out mouse and distribution of Syap1 in mouse brain and cultured motoneurons (2016) (5)
- Regenerative medicine: Bespoke cells for the human brain (2011) (5)
- Clinical characteristics of familial ALS patients carrying the pathogenic GGGGCC hexanucleotide repeat expansion of the C9ORF72 gene (2012) (5)
- Novel SOD1 N86K mutation is associated with a severe phenotype in familial ALS (2007) (5)
- Dynamic remodeling of ribosomes and endoplasmic reticulum in axon terminals of motoneurons. (2021) (4)
- A new postal code for dendritic mRNA transport in neurons (2011) (3)
- Keeping the balance: The noncoding RNA 7SK as a master regulator for neuron development and function (2021) (3)
- Neurodegenerative Diseases: Neurotrophic factors (2005) (3)
- Workshop on Trophic Factors in the Peripheral Nervous System. Capri, October 1991 (1992) (3)
- Absence of Plekhg5 Results in Myelin Infoldings Corresponding to an Impaired Schwann Cell Autophagy, and a Reduced T-Cell Infiltration Into Peripheral Nerves (2020) (3)
- Erratum: Glycinergic and GABAergic synaptic activity differentially regulate motoneuron survival and skeletal muscle innervation (Journal of Neuroscience February 2, 2005 (1249-1259)) (2005) (3)
- Ciliary neurotrophic factor (CNTF): physiological and pharmacological effects. (1995) (3)
- Rat ciliary neurotrophic factor (CNTF) (1993) (3)
- Loss of full-length hnRNP R isoform impairs DNA damage response in motoneurons by inhibiting Yb1 recruitment to chromatin (2021) (3)
- An ALS-associated mutation in human FUS reduces neurotransmission from C. elegans motor neurons to muscles (2019) (3)
- Faculty Opinions recommendation of Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice. (2010) (2)
- Leukemia Inhibitory Factor Deficiency Modulates the Immune Response and Limits Autoimmune Demyelination : A New Role for Neurotrophic Cytokines in Neuroinflammation 1 (2008) (2)
- Plastin 3 rescues cell surface translocation and activation of TrkB in spinal muscular atrophy. (2023) (2)
- Dynamic remodeling of ribosomes and endoplasmic reticulum in axon terminals of motoneurons (2021) (2)
- articleDownregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGFδ / δ mouse model of amyotrophic lateral sclerosis (2010) (2)
- hnRNP R negatively regulates transcription by modulating the association of P‐TEFb with 7SK and BRD4 (2022) (2)
- Measurement invariance testing of longitudinal neuropsychiatric test scores distinguishes pathological from normative cognitive decline and highlights its potential in early detection research. (2021) (2)
- Late abstracts (2011) (2)
- The 3rd German-Japanese Joint Workshop. Cell Death in the CNS: Molecules and Programs (1996) (2)
- Faculty Opinions recommendation of ETS transcription factor Erm controls subsynaptic gene expression in skeletal muscles. (2007) (1)
- SMN Is Physiologically Downregulated at Wild-Type Motor Nerve Terminals but Aggregates Together with Neurofilaments in SMA Mouse Models (2022) (1)
- Ciliary Neurotrophic Factor Induces Cholinergic Differentiation of Rat (2009) (1)
- Essential role of the mouse synapse associated protein Syap1 in circuits for spontaneous motor activity and rotarod balance (2019) (1)
- Ciliary neurotrophic factor enhances the rate of oligodendrocyte generation. (1996) (1)
- Role of CDNF in SOD1-G93A Mouse Model of Amyotrophic Lateral Sclerosis (2018) (1)
- Impaired dynamic interaction of axonal endoplasmic reticulum and ribosomes contributes to defective stimulus–response in spinal muscular atrophy (2022) (1)
- Molecular basis of neural repair mechanisms (2012) (1)
- SC1/PRDM4 is a critical mediator for cell death, mitosis and differentiation of neural stem cells. (2007) (1)
- Reply: Adult-onset distal spinal muscular atrophy: a new phenotype associated with KIF5A mutations. (2019) (1)
- Analysis of mutations in Survival of Motor Neuron (SMN1) gene through model systems. (2001) (1)
- Analysis of the survival of motor neuron (SMN1) gene mutations in Spinal Muscular Atrophy through models (2002) (0)
- Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology (2022) (0)
- Ciliary neurotrophic factor (CNTF) in the retina: age and disease related expression in humans and mice (2018) (0)
- has suggested a role for neurotrophins, none could be shown to promote motoneuron survival in vitro (1992) (0)
- Mouse mutants and cell culture models of motoneuron disease (2004) (0)
- SHORT COMMUNICATION The Gene for Ciliary, Neurotrophic F,actor (CNTF) Maps (1991) (0)
- Dopamine Modulates TrkB Turnover and BDNF Sensitivity in Striatal Medium Spiny Neurons (2022) (0)
- Characterization of the SOD1-G93A mouse model of Amyotrophic lateral sclerosis and a promising treatment for the disease (2018) (0)
- Faculty Opinions recommendation of Axonal-SMN (a-SMN), a protein isoform of the survival motor neuron gene, is specifically involved in axonogenesis. (2007) (0)
- Regenerationsverhalten von Motoneuronaxonen nach Ausriss, Replantation und Applikation von CNTF (ciliary neurotrophic factor) und BDNF (brain derived neurotrophic factor) (2005) (0)
- Use of active substances for the prophylaxis and / or treatment of diseases associated with cell growth disorders and test system for finding such active substances (2001) (0)
- The method and test system for the detection of nerve cell-protective substances (2001) (0)
- Transgenic mice carrying mutated Cu/Zn superoxide dismutase genes provide insights into the pathogenesis of human motorneuron diseases and may be useful as models in the development and testing of therapies. (1994) (0)
- Vascular and neural transcriptomics reveal stage-dependent pathways to inflammation and cognitive dysfunction in a rat model of hypertension (2023) (0)
- Faculty Opinions recommendation of Spinal muscular atrophy astrocytes exhibit abnormal calcium regulation and reduced growth factor production. (2013) (0)
- CDNF rescues motor neurons in models of amyotrophic lateral sclerosis by targeting endoplasmic reticulum stress. (2023) (0)
- Neurotrophic factors (2021) (0)
- Meeting of the Gbm Study Group " Molecular Neurobiology " " Perspectives in Molecular Neurobiology " (0)
- Test system for search or examination of active substances that influence the growth and / or survival of neurons (2001) (0)
- Motor Neuron Diseases: Molecular Mechanism, Pathophysiology, and Treatments (2006) (0)
- Bacteria transformed with expression plasmids encoding for the human NEUROTHROPHEN EYELASH factor (h-CNTF), their use in the production of h-CNTF, antibodies to h-CNTF, and the use of h-CNTF in medi hissers treatment. (1990) (0)
- Optimized Whole Transcriptome Profiling of Motor Axons. (2017) (0)
- Maass et al 2015 Neuroimage SI plasticity (2015) (0)
- presynaptic differentiation muscular atrophy point to widespread defects in axonal growth and Subcellular transcriptome alterations in a cell culture model of spinal Material Supplemental (2014) (0)
- Insulin-like growth factor 5 associates with human Aß plaques and promotes cognitive impairment (2022) (0)
- Reply (1996) (0)
- RegionalDistribution,Developmental Changes, and Cellular LocalizationofCNTF-mRNA and ProteinintheRat Brain (1991) (0)
- Plekhg5-regulated autophagy of synaptic vesicles reveals a pathogenic mechanism in motoneuron disease (2017) (0)
- Correction: An essential role of the mouse synapse-associated protein Syap1 in circuits for spontaneous motor activity and rotarod balance (2020) (0)
- erythroblasts of transcripts essential for differentiation of murine and human Ribosomal deficiencies in Diamond-Blackfan anemia impair translation (2014) (0)
- Molecular basis of neural repair mechanisms (2012) (0)
- Rapid Communication Members of Several Gene Families Influence Survival of Rat Motoneurons In Vitro and In Vivo (2009) (0)
- Ciliary Neurotrophic Factor - Potenzieller Modulator der Amyotrophen Lateralsklerose (2005) (0)
- Vascular Stat3 Promotes Angiogenesis and Neuroplasticity (2015) (0)
- The postnatal expression of ciliary neurotrophic factor in the sciatic nerve of rat-an immunohistochemical study (1995) (0)
- Subject Index Vol. 13, 2008 (2008) (0)
- Morphological and functional changes in motoneurons from Smn-deficient mice, an animal model for spinal muscular atrophy (SMA) (2005) (0)
- ILIARY NEUROTROPHIC FACTOR-IMMUNOREACTIVITY IN LFACTORY SENSORY NEURONS (2005) (0)
- Laminin induced local axonal translation of β-actin mRNA is impaired in SMN-deficient motoneurons (2012) (0)
- Genotyping protocols for commonly used SMA model mice (2011) (0)
- Network topology dynamics of circulating biomarkers and cognitive performance in older Cytomegalovirus-seropositive or -seronegative men and women (2019) (0)
- Faculty Opinions recommendation of Valproic acid reduces spatial working memory and cell proliferation in the hippocampus. (2010) (0)
- Faculty Opinions recommendation of MicroRNA-mediated conversion of human fibroblasts to neurons. (2011) (0)
- Oral session 39 — Growth factors (2005) (0)
- Faculty Opinions recommendation of Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease. (2005) (0)
- Impaired dynamic interaction of axonal endoplasmic reticulum and ribosomes contributes to defective stimulus–response in spinal muscular atrophy (2022) (0)
- A 3D cell culture system for bioengineering human neuromuscular junctions to model ALS (2023) (0)
- BRAIN-DERIVED NEUROTROPHIC FACTOR (1997) (0)
- Editorial Board (2007) (0)
- Faculty Opinions recommendation of G-quadruplex RNA structure as a signal for neurite mRNA targeting. (2011) (0)
- Abstracts Second Congress of the European Society for Clinical Neuropharmacology (1995) (0)
- STAGE-DEPENDENT RESPONSES OF VASCULAR AND PARENCHYMAL CELLS IN THE HYPERTENSIVE RAT BRAIN (2022) (0)
- Analysis of the modulating effect of pegylated IGF1 (pegIGF1) on the hearing function of a mouse model for auditory neuropathy (2021) (0)
- Hyper Phototransduction of Cone and Rod Photoreceptors in Cntf-/- Mice is Underpinned by Upregulated Opsins and RPE65 (2014) (0)
- Axonal Transport of mRNAs and Organelles: Pathophysiological Role in Motoneuron Disease (2007) (0)
- Contents Vol. 13, 2008 (2008) (0)
- Insulin-like growth factor 5 associates with human Aß plaques and promotes cognitive impairment (2022) (0)
- Faculty Opinions recommendation of Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice. (2010) (0)
- System: Mechanisms and Functions Neurotrophin-Mediated Rapid Signaling in the Central Nervous (2012) (0)
- Mechanisms which regulate the cholinergic phenotype in sympathetic, central cholinergic and spinal motoneurons (1998) (0)
- Faculty Opinions recommendation of The nuclear receptor tailless is required for neurogenesis in the adult subventricular zone. (2008) (0)
- Exome array analysis of rare and low frequency variants in amyotrophic lateral sclerosis (2019) (0)
- Dynamic remodeling of presynaptic endoplasmic reticulum is coordinated through actin and microtubule crosstalk and contributes to defective stimulus-response in Spinal Muscular Atrophy (2021) (0)
- Initial characterization of a Syap1 knock-out mouse and distribution of Syap1 in mouse brain and cultured motoneurons (2016) (0)
- Incidence of germline hMLH1 and hMSH2 mutations (HNPCC patients) among newly diagnosed colorectal cancers in a Slovenian population (2000) (0)
- Genome-wide structural variant analysis identifies risk loci for non-Alzheimer’s dementias (2023) (0)
- Loss of Tdp-43 disrupts the axonal transcriptome of motoneurons accompanied by impaired axonal translation and mitochondria function (2020) (0)
- Endogenous leukaemia inhibitory factor signalling reduces axonal damage in mice with EAE (2012) (0)
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What Schools Are Affiliated With Michael Sendtner?
Michael Sendtner is affiliated with the following schools: