Michael Stratton

Q: What Schools Are Affiliated With Michael Stratton

Michael Stratton is affiliated with the following schools: Institute of Cancer Research, Imperial College London, University of Oxford, Carleton University, Utrecht University

Michael Stratton's AcademicInfluence.com Rankings

Michael Stratton

Biology

#1878

World Rank

#3043

Historical Rank

Genetics

#240

World Rank

#287

Historical Rank

Molecular Biology

#317

World Rank

#322

Historical Rank

biology Degrees

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Biology

Michael Stratton's Degrees

Bachelors Biochemistry University of Oxford

Why Is Michael Stratton Influential?

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According to Wikipedia, Sir Michael Rudolf Stratton, is a British clinical scientist and the third director of the Wellcome Trust Sanger Institute. He currently heads the Cancer Genome Project and is a leader of the International Cancer Genome Consortium.

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Michael Stratton's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Mutations of the BRAF gene in human cancer (2002) (9903)
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls (2007) (9208)
Signatures of mutational processes in human cancer (2013) (7589)
The cancer genome (2009) (3127)
A census of human cancer genes (2004) (3087)
Patterns of somatic mutation in human cancer genomes (2007) (3038)
Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium. (1998) (2846)
Identification of the breast cancer susceptibility gene BRCA2 (1995) (2451)
COSMIC: the catalogue of somatic mutations in cancer (2011) (2432)
Genome-wide association study identifies novel breast cancer susceptibility loci (2007) (2351)
COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer (2010) (2300)
COSMIC: exploring the world's knowledge of somatic mutations in human cancer (2014) (2199)
Systematic identification of genomic markers of drug sensitivity in cancer cells (2012) (2134)
Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development (2011) (2047)
Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells (2012) (1904)
International network of cancer genome projects (2010) (1839)
A serine/threonine kinase gene defective in Peutz–Jeghers syndrome (1998) (1673)
A comprehensive catalogue of somatic mutations from a human cancer genome (2010) (1626)
Mutational Processes Molding the Genomes of 21 Breast Cancers (2012) (1622)
The landscape of cancer genes and mutational processes in breast cancer (2012) (1610)
Landscape of somatic mutations in 560 breast cancer whole genome sequences (2016) (1574)
Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients (2015) (1561)
Clinical and biological implications of driver mutations in myelodysplastic syndromes. (2013) (1493)
Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia (2011) (1488)
Identification of the breast cancer susceptibility gene BRCA2 (1996) (1451)
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants (2007) (1421)
The Human Cell Atlas (2017) (1285)
The patterns and dynamics of genomic instability in metastatic pancreatic cancer (2010) (1271)
A Landscape of Pharmacogenomic Interactions in Cancer (2016) (1254)
Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets (2015) (1253)
JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis. (2007) (1251)
The Life History of 21 Breast Cancers (2012) (1180)
Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma (2010) (1176)
Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes (2009) (1161)
The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website (2004) (1146)
High burden and pervasive positive selection of somatic mutations in normal human skin (2015) (1127)
BRAF and RAS mutations in human lung cancer and melanoma. (2002) (1106)
Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts. (2011) (1090)
A small-cell lung cancer genome with complex signatures of tobacco exposure (2010) (1031)
PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene (2007) (1005)
Deciphering Signatures of Mutational Processes Operative in Human Cancer (2013) (981)
The Catalogue of Somatic Mutations in Cancer (COSMIC) (2008) (938)
Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing (2008) (879)
Prevalence of BRCA1 and BRCA2 gene mutations in patients with early-onset breast cancer. (1999) (876)
Low-penetrance susceptibility to breast cancer due to CHEK2*1100delC in noncarriers of BRCA1 or BRCA2 mutations (2002) (860)
COMPLEX LANDSCAPES OF SOMATIC REARRANGEMENT IN HUMAN BREAST CANCER GENOMES (2009) (839)
Lung cancer: Intragenic ERBB2 kinase mutations in tumours (2004) (780)
Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma. (2013) (765)
Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles (2006) (733)
Clock-like mutational processes in human somatic cells (2015) (729)
ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles (2006) (728)
Mutational signatures associated with tobacco smoking in human cancer (2016) (722)
Genome-wide association study identifies five new breast cancer susceptibility loci (2010) (716)
Multifactorial analysis of differences between sporadic breast cancers and cancers involving BRCA1 and BRCA2 mutations. (1998) (700)
Identification of the familial cylindromatosis tumour-suppressor gene (2000) (683)
Signatures of mutation and selection in the cancer genome (2010) (671)
Somatic mutant clones colonize the human esophagus with age (2018) (670)
Prediction of BRCA1 Status in Patients with Breast Cancer Using Estrogen Receptor and Basal Phenotype (2005) (667)
Exploring the Genomes of Cancer Cells: Progress and Promise (2011) (667)
Subclonal diversification of primary breast cancer revealed by multiregion sequencing (2015) (656)
Tissue-specific mutation accumulation in human adult stem cells during life (2016) (645)
HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures (2017) (644)
Universal Patterns of Selection in Cancer and Somatic Tissues (2017) (607)
Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone (2013) (605)
Pathology of familial breast cancer: differences between breast cancers in carriers of BRCA1 or BRCA2 mutations and sporadic cases (1997) (604)
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls (2010) (600)
Somatic mutations of the histone H3K27 demethylase, UTX, in human cancer (2009) (595)
A common coding variant in CASP8 is associated with breast cancer risk (2007) (591)
A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation (2009) (582)
High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma (2014) (579)
A census of amplified and overexpressed human cancer genes (2010) (557)
A comprehensive model for familial breast cancer incorporating BRCA1, BRCA2 and other genes (2002) (528)
The emerging landscape of breast cancer susceptibility (2007) (511)
Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2 (2009) (502)
Germline mutations of the BRCA1 gene in breast and ovarian cancer families provide evidence for a genotype–phenotype correlation (1995) (490)
COSMIC (the Catalogue of Somatic Mutations in Cancer): a resource to investigate acquired mutations in human cancer (2009) (484)
Somatic mutations of the protein kinase gene family in human lung cancer. (2005) (468)
Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms. (2011) (466)
Genome-wide association study of copy number variation in 16,000 cases of eight common diseases and 3,000 shared controls (2010) (465)
Variation of risks of breast and ovarian cancer associated with different germline mutations of the BRCA2 gene (1997) (465)
Genomic Evolution of Breast Cancer Metastasis and Relapse (2017) (457)
Timing, rates and spectra of human germline mutation (2015) (455)
CHEK2*1100delC and susceptibility to breast cancer: a collaborative analysis involving 10,860 breast cancer cases and 9,065 controls from 10 studies. (2004) (442)
Instability of short tandem repeats (microsatellites) in human cancers (1994) (440)
Similarity of the phenotypic patterns associated with BRAF and KRAS mutations in colorectal neoplasia. (2002) (433)
Bayesian refinement of association signals for 14 loci in 3 common diseases (2012) (416)
High-resolution analysis of DNA copy number using oligonucleotide microarrays. (2004) (407)
Mutation analysis of 24 known cancer genes in the NCI-60 cell line set (2006) (406)
Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers (2007) (405)
Universal Patterns of Selection in Cancer and Somatic Tissues (2018) (403)
A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy. (2006) (401)
Mutational signatures: the patterns of somatic mutations hidden in cancer genomes (2014) (400)
Analysis of the Genetic Phylogeny of Multifocal Prostate Cancer Identifies Multiple Independent Clonal Expansions in Neoplastic and Morphologically Normal Prostate Tissue (2015) (399)
Cancer risks in two large breast cancer families linked to BRCA2 on chromosome 13q12-13. (1997) (393)
BRCA2 mutations in primary breast and ovarian cancers (1996) (390)
X-linked protocadherin 19 mutations cause female-limited epilepsy and cognitive impairment (2008) (386)
The landscape of somatic mutation in normal colorectal epithelial cells (2018) (378)
Patterns of somatic structural variation in human cancer genomes (2020) (377)
Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing (2008) (362)
Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer (2014) (358)
Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer (2014) (358)
Population dynamics of normal human blood inferred from somatic mutations (2018) (346)
Intra-tumour diversification in colorectal cancer at the single-cell level (2018) (341)
A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer (2005) (341)
RNA editing of human microRNAs (2006) (332)
Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer (2010) (329)
A genome-wide association study of testicular germ cell tumor (2009) (322)
BLUEPRINT to decode the epigenetic signature written in blood (2012) (320)
Haplotype and phenotype analysis of nine recurrent BRCA2 mutations in 111 families: results of an international study. (1998) (316)
Frequent activating FGFR2 mutations in endometrial carcinomas parallel germline mutations associated with craniosynostosis and skeletal dysplasia syndromes (2007) (315)
DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis (2013) (312)
DICER1 syndrome: clarifying the diagnosis, clinical features and management implications of a pleiotropic tumour predisposition syndrome (2011) (308)
Pharmacogenomic agreement between two cancer cell line data sets (2015) (306)
Genomics and the continuum of cancer care. (2011) (302)
RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia (2013) (301)
The genetics of breast cancer susceptibility. (1998) (300)
Whole genome DNA copy number changes identified by high density oligonucleotide arrays (2004) (298)
Genome sequencing of normal cells reveals developmental lineages and mutational processes (2014) (297)
Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers (2015) (295)
Genome Sequencing and Analysis of the Tasmanian Devil and Its Transmissible Cancer (2012) (292)
Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes (2014) (289)
A survey of RNA editing in human brain. (2004) (276)
Localization to Xq27 of a susceptibility gene for testicular germ-cell tumours (2000) (251)
The mutational landscape of normal human endometrial epithelium (2018) (250)
Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancer (2014) (248)
Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation (2007) (248)
Characterizing Mutational Signatures in Human Cancer Cell Lines Reveals Episodic APOBEC Mutagenesis (2019) (242)
Genome-Wide Mutational Signatures of Aristolochic Acid and Its Application as a Screening Tool (2013) (241)
The pathology of familial breast cancer: histological features of cancers in families not attributable to mutations in BRCA1 or BRCA2. (2000) (239)
Recurrent PTPRB and PLCG1 mutations in angiosarcoma (2014) (238)
Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment. (2007) (233)
A germline mutation in the androgen receptor gene in two brothers with breast cancer and Reifenstein syndrome (1992) (233)
Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells (2018) (230)
Whole exome sequencing of adenoid cystic carcinoma. (2013) (226)
COSMIC 2005 (2006) (224)
Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia (2014) (224)
Atypical ductal hyperplasia of the breast: clonal proliferation with loss of heterozygosity on chromosomes 16q and 17p. (1995) (222)
Recurrent KRAS codon 146 mutations in human colorectal cancer (2006) (222)
Ovarian cancer risk in BRCA1 carriers is modified by the HRAS1 variable number of tandem repeat (VNTR) locus (1996) (222)
SLC9A6 mutations cause X-linked mental retardation, microcephaly, epilepsy, and ataxia, a phenotype mimicking Angelman syndrome. (2008) (212)
PICNIC: an algorithm to predict absolute allelic copy number variation with microarray cancer data (2009) (211)
The Y deletion gr/gr and susceptibility to testicular germ cell tumor. (2005) (208)
Mutational signatures of ionizing radiation in second malignancies (2016) (207)
Submicroscopic duplications of the hydroxysteroid dehydrogenase HSD17B10 and the E3 ubiquitin ligase HUWE1 are associated with mental retardation. (2008) (205)
Somatic mutations reveal asymmetric cellular dynamics in the early human embryo (2017) (204)
Tobacco exposure and somatic mutations in normal human bronchial epithelium (2019) (203)
Familial nontoxic multinodular thyroid goiter locus maps to chromosome 14q but does not account for familial nonmedullary thyroid cancer. (1997) (203)
Mutations in CUL4B, which encodes a ubiquitin E3 ligase subunit, cause an X-linked mental retardation syndrome associated with aggressive outbursts, seizures, relative macrocephaly, central obesity, hypogonadism, pes cavus, and tremor. (2007) (199)
The topography of mutational processes in breast cancer genomes (2016) (198)
Comprehensive molecular characterization of mitochondrial genomes in human cancers (2017) (197)
Use of cancer‐specific genomic rearrangements to quantify disease burden in plasma from patients with solid tumors (2010) (194)
Disruption at the PTCHD1 Locus on Xp22.11 in Autism Spectrum Disorder and Intellectual Disability (2010) (193)
Somatic mutations and clonal dynamics in healthy and cirrhotic human liver (2019) (191)
The BRC repeats are conserved in mammalian BRCA2 proteins. (1997) (188)
Loss of the Mismatch Repair Protein MSH6 in Human Glioblastomas Is Associated with Tumor Progression during Temozolomide Treatment (2007) (186)
Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution. (2007) (185)
Mutations in FRMD7, a newly identified member of the FERM family, cause X-linked idiopathic congenital nystagmus (2006) (184)
Distinct genomic profiles in hereditary breast tumors identified by array-based comparative genomic hybridization. (2005) (179)
Mutation of the p53 gene in human soft tissue sarcomas: association with abnormalities of the RB1 gene. (1990) (179)
A polymorphic stop codon in BRCA2 (1996) (178)
Haplotype and phenotype analysis of six recurrent BRCA1 mutations in 61 families: results of an international study. (1996) (177)
The original Lujan syndrome family has a novel missense mutation (p.N1007S) in the MED12 gene (2007) (175)
Mutation allele burden remains unchanged in chronic myelomonocytic leukaemia responding to hypomethylating agents (2016) (175)
The Life History of 21 Breast Cancers (2015) (173)
Familial male breast cancer is not linked to the BRCA1 locus on chromosome 17q (1994) (173)
The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature (2018) (172)
Mutations in the DLG3 gene cause nonsyndromic X-linked mental retardation. (2004) (170)
The gene for cherubism maps to chromosome 4p16.3. (1999) (170)
Statistical Analysis of Pathogenicity of Somatic Mutations in Cancer (2006) (167)
Genetic alterations in ‘normal’ luminal and myoepithelial cells of the breast (1999) (166)
Characterization of the human cell line TE671. (1989) (165)
The genome as a record of environmental exposure (2015) (161)
Detection of point mutations in N-ras and K-ras genes of human embryonal rhabdomyosarcomas using oligonucleotide probes and the polymerase chain reaction. (1989) (161)
Frequent mutation of the major cartilage collagen gene COL2A1 in chondrosarcoma (2013) (160)
Mutations in ZDHHC9, which encodes a palmitoyltransferase of NRAS and HRAS, cause X-linked mental retardation associated with a Marfanoid habitus. (2007) (160)
Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma (2017) (157)
The V617F JAK2 mutation is uncommon in cancers and in myeloid malignancies other than the classic myeloproliferative disorders. (2005) (157)
Cancer and genomics (2001) (156)
C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency (2014) (155)
Familial cylindromatosis (turban tumour syndrome) gene localised to chromosome 16q12–q13: evidence for its role as a tumour suppressor gene (1995) (152)
Oligosaccharyltransferase-subunit mutations in nonsyndromic mental retardation. (2008) (151)
Somatic mutation landscapes at single-molecule resolution (2021) (150)
Evidence for a familial Wilms' tumour gene (FWT1) on chromosome 17q12–q21 (1996) (150)
Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14 (2013) (149)
Variants in CHEK2 other than 1100delC do not make a major contribution to breast cancer susceptibility. (2003) (146)
A genome wide linkage search for breast cancer susceptibility genes (2006) (146)
A mutational signature in gastric cancer suggests therapeutic strategies (2015) (145)
Single-cell paired-end genome sequencing reveals structural variation per cell cycle (2013) (143)
Transmissible Dog Cancer Genome Reveals the Origin and History of an Ancient Cell Lineage (2014) (142)
SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair (2015) (140)
Mutations in the guanine nucleotide exchange factor gene IQSEC2 cause nonsyndromic intellectual disability (2010) (139)
Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro (2021) (136)
Common BRCA1 variants and susceptibility to breast and ovarian cancer in the general population. (1997) (136)
Genome-wide linkage screen for testicular germ cell tumour susceptibility loci. (2006) (133)
The frequency of germ-line mutations in the breast cancer predisposition genes BRCA1 and BRCA2 in familial prostate cancer. The Cancer Research Campaign/British Prostate Group United Kingdom Familial Prostate Cancer Study Collaborators. (2000) (131)
Extensive heterogeneity in somatic mutation and selection in the human bladder (2020) (129)
Estimation of rearrangement phylogeny for cancer genomes. (2012) (128)
Detection of allelic imbalance indicates that a proportion of mammary hyperplasia of usual type are clonal, neoplastic proliferations. (1996) (127)
Feedback Circuit among INK4 Tumor Suppressors Constrains Human Glioblastoma Development (2008) (126)
Mutations in the p53 gene in schistosomal bladder cancer: a study of 92 tumours from Egyptian patients and a comparison between mutational spectra from schistosomal and non-schistosomal urothelial tumours. (1995) (125)
LKB1/KRAS mutant lung cancers constitute a genetic subset of NSCLC with increased sensitivity to MAPK and mTOR signalling inhibition (2009) (125)
Loss of heterozygosity in ductal carcinoma in situ of the breast (1995) (124)
Low frequency of somatic mutations in the LKB1/Peutz-Jeghers syndrome gene in sporadic breast cancer. (1998) (121)
Fine-scale survey of X chromosome copy number variants and indels underlying intellectual disability. (2010) (120)
Inherited susceptibility to colorectal adenomas and carcinomas: evidence for a new predisposition gene on 15q14-q22. (1999) (116)
A proteomic chronology of gene expression through the cell cycle in human myeloid leukemia cells (2014) (116)
Biallelic BRCA2 mutations are associated with multiple malignancies in childhood including familial Wilms tumour (2005) (114)
SigProfilerMatrixGenerator: a tool for visualizing and exploring patterns of small mutational events (2019) (111)
Somatic mutation rates scale with lifespan across mammals (2021) (111)
A whole-genome sequence and transcriptome perspective on HER2-positive breast cancers (2016) (110)
Loss of heterozygosity in sporadic breast tumours at the BRCA2 locus on chromosome 13q12-q13. (1995) (110)
Evaluation of linkage of breast cancer to the putative BRCA3 locus on chromosome 13q21 in 128 multiple case families from the Breast Cancer Linkage Consortium (2002) (106)
Sequence analysis of the protein kinase gene family in human testicular germ‐cell tumors of adolescents and adults (2006) (105)
CASK mutations are frequent in males and cause X-linked nystagmus and variable XLMR phenotypes (2010) (104)
Absence of methylation of CpG dinucleotides within the promoter of the breast cancer susceptibility gene BRCA2 in normal tissues and in breast and ovarian cancers. (1997) (103)
Does a genotoxic carcinogen contribute to human breast cancer? The value of mutational spectra in unravelling the aetiology of cancer. (1993) (102)
Genome-wide screening for complete genetic loss in prostate cancer by comparative hybridization onto cDNA microarrays (2003) (102)
GLO1—A novel amplified gene in human cancer (2010) (102)
The mutational landscape of human somatic and germline cells (2020) (101)
Mutations in the gene encoding the Sigma 2 subunit of the adaptor protein 1 complex, AP1S2, cause X-linked mental retardation. (2006) (100)
A survey of homozygous deletions in human cancer genomes. (2005) (100)
Somatic mutations of KIT in familial testicular germ cell tumours (2004) (98)
Loss of heterozygosity in lobular carcinoma in situ of the breast (1995) (98)
Recurrent rearrangements of FOS and FOSB define osteoblastoma (2018) (98)
Imidazopurinones are markers of physiological genomic damage linked to DNA instability and glyoxalase 1-associated tumour multidrug resistance (2010) (97)
The driver landscape of sporadic chordoma (2017) (96)
The exon 13 duplication in the BRCA1 gene is a founder mutation present in geographically diverse populations. The BRCA1 Exon 13 Duplication Screening Group. (2000) (96)
A gene for lymphedema-distichiasis maps to 16q24.3. (1999) (96)
Processed pseudogenes acquired somatically during cancer development (2014) (87)
BRCA1 and BRCA2 mutation frequency in women evaluated in a breast cancer risk evaluation clinic. (2002) (87)
Germline mutations in BRCA1 and BRCA2 in breast-ovarian families from a breast cancer risk evaluation clinic. (2001) (87)
Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration (2016) (86)
Tandem duplication of chromosomal segments is common in ovarian and breast cancer genomes (2012) (86)
Somatic KIT mutations occur predominantly in seminoma germ cell tumors and are not predictive of bilateral disease: Report of 220 tumors and review of literature (2008) (84)
Structural alterations of the RB1 gene in human soft tissue tumours. (1989) (82)
Epilepsy and mental retardation limited to females with PCDH19 mutations can present de novo or in single generation families (2009) (81)
Somatic Evolution in Non-neoplastic IBD-Affected Colon (2019) (78)
Mutations in the BRWD3 gene cause X-linked mental retardation associated with macrocephaly. (2007) (77)
Clonal dynamics of haematopoiesis across the human lifespan (2021) (75)
Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells (2015) (75)
Evaluation of Fanconi Anemia genes in familial breast cancer predisposition. (2003) (72)
Decoding the fine-scale structure of a breast cancer genome and transcriptome. (2006) (71)
Recurrent intragenic rearrangements of EGFR and BRAF in soft tissue tumors of infants (2018) (71)
The circular RNome of primary breast cancer (2019) (70)
BRCA1 and BRCA2 mutations in breast cancer families with multiple primary cancers. (2000) (70)
A comprehensive analysis of MNG1, TCO1, fPTC, PTEN, TSHR, and TRKA in familial nonmedullary thyroid cancer: confirmation of linkage to TCO1. (2001) (69)
Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors (2017) (67)
The cylindromatosis gene (cyld1) on chromosome 16q may be the only tumour suppressor gene involved in the development of cylindromas. (1996) (67)
Predisposition gene identification in common cancers by exome sequencing: insights from familial breast cancer (2012) (67)
Whole-Genome Sequencing Reveals Breast Cancers with Mismatch Repair Deficiency. (2017) (67)
A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers (2017) (67)
Recent advances in understanding of genetic susceptibility to breast cancer. (1996) (66)
Combinations of PARP Inhibitors with Temozolomide Drive PARP1 Trapping and Apoptosis in Ewing’s Sarcoma (2015) (65)
Constitutional mutation in exon 8 of the p53 gene in a patient with multiple primary tumours: molecular and immunohistochemical findings. (1993) (65)
Cloning, chromosomal mapping and expression pattern of the mouse Brca2 gene. (1997) (64)
Heterozygosity for mutations in the ataxia telangiectasia gene is not a major cause of radiotherapy complications in breast cancer patients. (1998) (64)
Natural history of Christianson syndrome (2010) (64)
Genome resequencing and genetic variation (2008) (63)
Evaluation of RAD50 in familial breast cancer predisposition (2006) (63)
Embryonal precursors of Wilms tumor (2019) (62)
Structure of the met protein and variation of met protein kinase activity among human tumour cell lines. (1988) (62)
A Multicenter Study of Cancer Incidence in CHEK2 1100delC Mutation Carriers (2006) (61)
Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data (2019) (61)
Cytogenetic abnormalities in human ependymomas (1989) (60)
A small cell lung cancer genome reports complex tobacco exposure signatures (2009) (58)
Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor (2020) (58)
BRAF gene is somatically mutated but does not make a major contribution to malignant melanoma susceptibility: the Italian Melanoma Intergroup Study. (2004) (56)
The Human Cell Atlas White Paper (2018) (55)
Hypomorphic temperature-sensitive alleles of NSDHL cause CK syndrome. (2010) (53)
A novel Gln358Glu mutation in ectodysplasin A associated with X‐linked dominant incisor hypodontia (2007) (53)
Linkage and LOH studies in 19 cylindromatosis families show no evidence of genetic heterogeneity and refine the CYLD locus on chromosome 16q12–q13 (2000) (53)
Localisation of susceptibility genes for familial testicular germ cell tumour (2003) (53)
Evidence for susceptibility genes to familial Wilms tumour in addition to WT1, FWT1 and FWT2 (2000) (52)
Somatic evolution and global expansion of an ancient transmissible cancer lineage (2019) (52)
Constitutional translocation breakpoint mapping by genome-wide paired-end sequencing identifies HACE1 as a putative Wilms tumour susceptibility gene (2009) (52)
Identification and characterization of two novel JARID1C mutations: suggestion of an emerging genotype–phenotype correlation (2010) (52)
Extensive phylogenies of human development inferred from somatic mutations (2021) (52)
Screening for BRCA2 mutations in 81 Dutch breast–ovarian cancer families (1999) (51)
Familial cancer syndromes (1994) (51)
Testicular microlithiasis as a familial risk factor for testicular germ cell tumour (2007) (51)
Data mining using the Catalogue of Somatic Mutations in Cancer BioMart (2011) (51)
Hereditary predisposition to breast cancer. (1996) (50)
Reliable detection of somatic mutations in solid tissues by laser-capture microdissection and low-input DNA sequencing (2020) (49)
Mutations of BRAF and KRAS in gastric cancer and their association with microsatellite instability (2004) (48)
HPC2/ELAC2 polymorphisms and prostate cancer risk: analysis by age of onset of disease (2002) (47)
The International Testicular Cancer Linkage Consortium: a clinicopathologic descriptive analysis of 461 familial malignant testicular germ cell tumor kindred. (2010) (46)
Genomic evidence supports a clonal diaspora model for metastases of esophageal adenocarcinoma (2018) (45)
Absence of evidence for a familial breast cancer susceptibility gene at chromosome 8p12-p22 (2000) (45)
Rapid detection of DNA sequence variants by conformation-sensitive capillary electrophoresis. (2000) (45)
Mutational signatures in esophageal squamous cell carcinoma from eight countries with varying incidence (2021) (45)
Increased somatic mutation burdens in normal human cells due to defective DNA polymerases (2021) (44)
The genetics of familial breast cancer and their practical implications. (1994) (44)
Gene-gene interactions in breast cancer susceptibility. (2012) (42)
Novel candidate cancer genes identified by a large-scale cross-species comparative oncogenomics approach. (2010) (42)
Convergent somatic mutations in metabolism genes in chronic liver disease (2021) (42)
Confirmation of FWT1 as a Wilms’ tumour susceptibility gene and phenotypic characteristics of Wilms’ tumour attributable to FWT1 (1998) (41)
Sex differences in oncogenic mutational processes (2019) (41)
Comprehensive analysis of indels in whole-genome microsatellite regions and microsatellite instability across 21 cancer types (2018) (41)
High throughput DNA sequence variant detection by conformation sensitive capillary electrophoresis and automated peak comparison. (2006) (40)
Genetics of non-medullary thyroid cancer. (1995) (40)
Lobular carcinoma in situ of the breast is not caused by constitutional mutations in the E-cadherin gene (2000) (40)
A novel X-linked trichothiodystrophy associated with a nonsense mutation in RNF113A (2015) (39)
Analysis of the DND1 gene in men with sporadic and familial testicular germ cell tumors (2008) (39)
Estrogen Receptor Status Could Modulate the Genomic Pattern in Familial and Sporadic Breast Cancer (2007) (38)
Mutations in the RSK2(RPS6KA3) gene cause Coffin–Lowry syndrome and nonsyndromic X‐linked mental retardation (2006) (37)
Genetic heterogeneity and localization of a familial breast-ovarian cancer gene on chromosome 17q12-q21. (1993) (37)
Direct Transcriptional Consequences of Somatic Mutation in Breast Cancer (2016) (36)
Allelotype of uterine leiomyomas. (1999) (35)
Screening for ESR mutations in breast and ovarian cancer patients (1997) (32)
Somatic mutations in human cancer: insights from resequencing the protein kinase gene family. (2005) (32)
Mutation in Rpa1 results in defective DNA double-strand break repair, chromosomal instability, and cancer in mice (2004) (31)
Multi-stage genome-wide association study identifies new susceptibility locus for testicular germ cell tumour on chromosome 3q25. (2015) (31)
Breast cancer susceptibility: a complex disease unravels. (1995) (30)
A Pathogenic Mosaic TP53 Mutation in Two Germ Layers Detected by Next Generation Sequencing (2014) (29)
Somatic structural rearrangements in genetically engineered mouse mammary tumors (2010) (28)
Journeys into the genome of cancer cells (2013) (28)
The p53 gene in human cancer. (1992) (28)
Lessons learnt from large-scale exon re-sequencing of the X chromosome (2009) (27)
Misidentified cell (1989) (27)
An interstitial tandem duplication of 9p23-24 coexists with a mutation in the BRCA2 gene in the germ line of three brothers with breast cancer. (1998) (27)
Variants in CHEK 2 Other than 1100 delC Do Not Make a Major Contribution to Breast Cancer Susceptibility (2003) (27)
Linkage analysis of 56 multiplex families excludes the Cowden disease genePTEN as a major contributor to familial breast cancer (1999) (27)
Mechanisms of APOBEC3 mutagenesis in human cancer cells (2022) (25)
BRCA1 and BRCA2 germline mutations in Sardinian breast cancer families and their implications for genetic counseling. (2002) (24)
Soft tissue tumours: the genetic basis of development. (1991) (24)
A physical analysis of the Y chromosome shows no additional deletions, other than Gr/Gr, associated with testicular germ cell tumour (2007) (24)
Signatures of mutational processes in human cancer this access benefits you. Your matters (2013) (23)
Extended Data Figure 5 (2014) (22)
Universal Patterns of Selection in Cancer and Somatic Tissues (2017) (22)
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (2020) (22)
Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumors (2022) (20)
Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations (2017) (20)
Localisation of the breast‐ovarian cancer susceptibility gene (BRCAI) on 17q12–21 to an interval of ⩽IcM (1994) (19)
Development, maturation, and maintenance of human prostate inferred from somatic mutations (2021) (19)
Cancer: Understanding the target (2004) (19)
Refined mapping of X-linked reticulate pigmentary disorder and sequencing of candidate genes (2008) (19)
The familial Wilms' tumour susceptibility gene, FWT1, may not be a tumour suppressor gene (1997) (19)
Detection of transforming genes by transfection of DNA from primary soft-tissue tumours. (1991) (18)
Younger age-at-diagnosis for familial malignant testicular germ cell tumor (2009) (18)
Familial craniofacial fibrous dysplasia: absence of linkage toGNAS1 and the gene for cherubism (2000) (18)
Tissue-Biased Expansion of DNMT3A-Mutant Clones in a Mosaic Individual Is Associated with Conserved Epigenetic Erosion. (2020) (18)
Evolution and lineage dynamics of a transmissible cancer in Tasmanian devils (2020) (17)
Using gene carrier probability to select high risk families for identifying germline mutations in breast cancer susceptibility genes. (1998) (17)
Contribution of germline MLH1 and MSH2 mutations to lobular carcinoma in situ of the breast. (2001) (17)
Short inverted repeats contribute to localized mutability in human somatic cells (2017) (16)
Corrigendum: Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue (2015) (16)
In vitro differential sensitivity of melanomas to phenothiazines is based on the presence of codon 600 BRAF mutation (2008) (15)
Sequencing analysis of BRAF mutations in human cancers. (2006) (15)
Case of interstitial 12q deletion in association with Wilms tumor. (2001) (15)
AutoCSA, an algorithm for high throughput DNA sequence variant detection in cancer genomes (2007) (14)
A case of cerebellar medulloblastoma with a single chromosome abnormality. (1991) (14)
Tobacco smoking and somatic mutations in human bronchial epithelium (2020) (14)
A 45-year follow-up of kindred 107 and the search for BRCA2. (1995) (14)
A missense mutation in the BRCA2 gene in three siblings with ovarian cancer. (1998) (13)
Mutagenicity of acrylamide and glycidamide in human TP53 knock-in (Hupki) mouse embryo fibroblasts (2020) (13)
Corrigendum: Signatures of mutational processes in human cancer (2013) (13)
Mutation and association analysis of GEN1 in breast cancer susceptibility (2010) (12)
Life without mismatch repair (2021) (11)
Corrigendum: Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition (2016) (11)
Elevated somatic mutation burdens in normal human cells due to defective DNA polymerases (2020) (11)
The Gene for Cherubism Maps to Chromosome (2001) (11)
Identification and characterization of two novel JARID1C mutations: suggestion of an emerging genotype-phenotype correlation (2012) (11)
Molecular Biology for Oncologists (1993) (11)
Somatic Mutation of SF3B1, a Gene Encoding a Core Component of RNA Splicing Machinery, in Myelodysplasia with Ring Sideroblasts (2011) (10)
Author response: The Human Cell Atlas (2017) (10)
Inherited MUTYH mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells (2021) (10)
Penetrance of mutations in the familial Wilms tumor gene FWT1. (2000) (10)
Extraction and Enzymatic Amplification of DNA from Paraffin-Embedded Specimens (1991) (10)
Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences (2019) (10)
Genomics of Drug Sensitivity in Cancer (GDSC): A resource for biomarker discovery in cancer cells (2016) (9)
Mutational landscape of normal epithelial cells in Lynch Syndrome patients (2022) (7)
Recurrent deletion of ZNF630 at Xp11.23 is not associated with mental retardation (2010) (7)
Abstract 2: Metabolomics analysis reveals distinct profiles of non-muscle invasive and muscle-invasive bladder cancer (2016) (7)
Recurrent histone mutations in T‐cell acute lymphoblastic leukaemia (2018) (7)
The Genetics of Testicular Germ Cell Tumours (2002) (7)
5 Proffered Paper: The Life History of 21 Breast Cancers (2012) (6)
Familial breast cancer (1996) (6)
Corrigendum: Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells. (2016) (6)
Dinucleotide repeat polymorphism at the SIS locus. (1990) (6)
O-001 Clinical and biological implications of gene mutations in MDS (2013) (6)
Correction: Corrigendum: High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma (2016) (6)
The APOBEC3A deaminase drives episodic mutagenesis in cancer cells (2021) (6)
Familial testicular cancer: lack of evidence for trinucleotide repeat expansions and association with PKD1 in one family (1999) (5)
Erratum: The Life History of 21 Breast Cancers (Cell 149 (994-1007)) (2015) (5)
Erratum: Corrigendum: A common coding variant in CASP8 is associated with breast cancer risk (2007) (5)
The evolution of two transmissible cancers in Tasmanian devils (2022) (4)
Extended Data Table 1 (2014) (4)
Supplementary file 1. (2015) (4)
Exclusion of biglycan mutations in a cohort of patients with neuromuscular disorders (2008) (4)
Identification of Novel Somatic Mutations in SF3B1, a Gene Encoding a Core Component of RNA Splicing Machinery, in Myelodysplasia with Ring Sideroblasts and Other Common Cancers (2011) (4)
Supplementary file 3. (2014) (4)
Arena syndrome is caused by a missense mutation in PLP1 (2009) (3)
Terminology for carcinoma-in-situ of the breast (1996) (3)
Molecular biology for clinical oncologists (2nd ed.) (1996) (3)
An international report on bacterial communities in esophageal squamous cell carcinoma (2021) (3)
High Throughput Targeted Gene Sequencing in 738 Myelodysplastic Syndromes Patients Reveals Novel Oncogenic Genes, Rare Driver Mutations and Complex Molecular Signatures with Potential Impact for Patient Diagnosis and Prognosis in the Clinic (2012) (3)
The BRAF gene is frequently mutated in malignant melanoma. (2004) (3)
Mutagenicity of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP) in human TP53 knock-in (Hupki) mouse embryo fibroblasts. (2020) (3)
Personally Tailored Risk Prediction of AML Based on Comprehensive Genomic and Clinical Data (2015) (3)
Use of tumor exome analysis to reveal neo-antigen-specific T-cell reactivity in ipilimumab-responsive melanoma. (2013) (3)
TO JMG Biallelic BRCA 2 mutations are associated with multiple malignancies in childhood including familial Wilms tumour (2005) (3)
The Genomic Landscape of TEL-AML1+ (ETV6-RUNX1) Acute Lymphoblastic Leukaemia (2011) (3)
Author response: DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis (2013) (2)
Supplementary file 2. (2014) (2)
The mutational profile and clonal landscape of the inflammatory bowel disease affected colon (2019) (2)
Corrigendum: Mutations in FRMD7, a newly identified member of the FERM family, cause X-linked idiopathic congenital nystagmus (2011) (2)
Author Correction: The repertoire of mutational signatures in human cancer (2020) (2)
604 Cancer Genomics, Epigenetics and Genomic Instability. Mutational Processes Shaping the Genomes of Twenty-one Breast Cancers (2012) (2)
Extensive phylogenies of human development reveal variable embryonic patterns (2020) (2)
Mining cancer genomes in COSMIC (2012) (2)
Evolution of the cancer genome (2010) (2)
Human non-small cell lung cancer (NSCLC) cell lines with inactivated LKB1 and KRAS mutations are sensitive to MEK inhibition (2008) (2)
1804 The driver landscape of breast cancer metastasis and relapse (2015) (2)
APOBEC mutagenesis is a common process in normal human small intestine (2023) (2)
BRCA 1 and BRCA 2 Mutations in Breast Cancer Families with Multiple Primary Cancers 1 (2000) (2)
The A-T gene does not make a major contribution to familial breast cancer (1993) (2)
Mutations in a novel member of the FERM family, FRMD7 cause X-linked idiopathic congenital nystagmus (NYS1) (2008) (2)
50 The identification of novel somatic mutations in MDS by whole exome sequencing (2011) (2)
Abstract 4322: The landscape of mitochondrial DNA mutations in human cancer (2014) (2)
Corrigendum: A common coding variant in CASP8 is associated with breast cancer risk (2007) (1)
Corrigendum to: CASK mutations are frequent in males and cause X-linked nystagmus and variable XLMR phenotypes (2010) (1)
Identification of mutations of the SWI/SNF complex gene PBRM1 by exome sequencing in renal carcinoma. (2011) (1)
Whole-genome sequencing identifies recurrent mutations in chronic lymphocyticleukaemia (2011) (1)
DICER1 syndrome - a pleiotropic tumor predisposition syndrome (2010) (1)
Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences (2019) (1)
355 Cancer gene discovery (2003) (1)
Corrigendum: Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma (2012) (1)
407: Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia (2014) (1)
Abstract 62: COSMIC: Combining the world's knowledge of somatic mutation in human cancer (2015) (1)
460: COSMIC: Exploring novel cancer biomarkers (2014) (1)
The impact of the cancer genome project and high-throughput analyses on personalised oncology: today and tomorrow (2012) (1)
Genomic heterogeneity in primary breast cancer: Clinical implications. (2014) (1)
41 Genome-wide mutational signatures of aristolochic acid in urothelial cancer (2014) (1)
Abstract 5285: COSMIC: comprehensively exploring oncogenomics (2016) (1)
Abstract 2218: Genomic characterisation of 1015 cancer cell-lines (2014) (1)
DNA sequence analysis of known cancer genes in the NCI-60 cell lines. (2006) (1)
Mutational Signatures in Human Cancer (2014) (1)
35 The Genomics of Drug Sensitivity in Cancer (2012) (1)
If You Can Talk, You Can Sing. (2005) (1)
Abstract 3959: COSMIC: Mining the world's knowledge on somatic cancer mutations (2012) (1)
Supplementary File 4 (2014) (1)
The pathology of inherited breast tumours (2000) (1)
Abstract 90: Mining for cancer causing mutations in whole genome sequence data (2010) (1)
Corrigendum: Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone (2014) (1)
Author Correction: Pan-cancer analysis of whole genomes (2023) (1)
Abstract 5326: COSMIC: Enhancing the world's knowledge of somatic mutations in human cancer (2014) (1)
Clonal Dynamics of Normal Haematopoiesis with Human Ageing (2021) (1)
143 INVITED Evolution of the Cancer Genome (2011) (1)
The driver landscape of angiosarcoma. (2014) (1)
BRCA 1 / BRCA 2 prediction model (2004) (1)
GENOMIC MEDICINE Genomics and the Continuum of Cancer Care (2011) (1)
Characteristics of a single-centre series of familial testicular germ cell tumours. (2006) (1)
Resource A Landscape of Pharmacogenomic Interactions in Cancer Graphical Abstract Highlights (2016) (1)
Abstract 93: COSMIC: The catalogue of somatic mutations in cancer receives full genome variant annotations (2010) (1)
Human Lung Cancer Somatic Mutations of the Protein Kinase Gene Family in Updated (2005) (1)
Corrigendum: A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers (2017) (1)
The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature (2018) (1)
G05 : Exome sequencing of 243 liver tumors identifies new mutational signatures and potential therapeutic targets (2015) (0)
Abstract 1158: Modulation of splicing by inhibiting the kinase SRPK1 as a novel therapeutic strategy in myeloid leukemia (2017) (0)
Mutation and association analysis of in breast cancer susceptibility (2020) (0)
DOP50 The landscape of somatic mutations in non-neoplastic IBD-affected colon (2020) (0)
Mechanisms of APOBEC3 mutagenesis in human cancer cells (2022) (0)
557 The Genomic Landscape of ER Positive, HER2 Negative Breast Cancer (2012) (0)
Abstract 2342: Tobacco exposure and somatic mutations in normal bronchial epithelia (2020) (0)
Genomic evidence supports a clonal diaspora model for metastases of esophageal adenocarcinoma (2020) (0)
INVITED SESSION, SESSION 42: PARAMEDICAL INVITED SESSION – EMERGING TECHNOLOGIES IN HUMAN IVF LABORATORIES, Tuesday 5 July 2011 14:00 – 15:00 (2011) (0)
signatures related to carcinogens and DNA repair deficiency whole genome sequencing reveals mutational (2014) (0)
Abstract 1168: Mutational processes in tumour-adjacent normal kidneys across countries with varying cancer incidence rates (2023) (0)
Screening 101 renal cancers for somatic mutations in 3,726 genes (2008) (0)
Abstract A009: Benchmarking the foreign antigen space of human malignancies (2016) (0)
1818 Evolution from primary breast cancer to relapse and metastasis (2015) (0)
Tubio retrotransposition in cancer genomes Extensive transduction of nonrepetitive DNA mediated by L 1 (2014) (0)
SigProfilerMatrixGenerator: a tool for visualizing and exploring patterns of small mutational events (2019) (0)
Abstract 46: COSMIC: Enhancing the analysis of whole somatic mutant tumor genomes (2011) (0)
Abstract 5055: Exploring the subclonal architecture of breast cancer (2012) (0)
The genome as a record for environmental exposure to polycyclic aromatic hydrocarbons (2017) (0)
Opitz-Kaveggia (FG) and Lujan syndromes are allelic having mutations in the MED12 gene (2007) (0)
Author Correction: Inferring structural variant cancer cell fraction (2022) (0)
A systematic somatic mutation screen of 680Mb of renal cancer DNA (2008) (0)
Abstract 226: Recurrent trisomies, variable selection and precancerous evolution in the normal gastric epithelium (2022) (0)
Author Correction: Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors (2018) (0)
NIHMS662581-supplement-Supplementary data (2016) (0)
853 Pharmacogenomic Profiling of Drugs in Cancer Cells Identifies Novel Biomarkers of Sensitivity (2012) (0)
NIHMS662581-supplement-Supplementary data (2016) (0)
Towards the next-generation of cancer cell lines: Derivation of an organoid biobank (2016) (0)
Recurrent rearrangements of FOS and FOSB define osteoblastoma (2018) (0)
Genes, chromosomes and disease (2009) (0)
The V617F JAK2 Mutation Is Uncommon in Cancers and Mutations in STAT5A, STAT5B and the JAK Family Genes Do Not Account for V617F Negative Myeloproliferative Disorders. (2005) (0)
Abstract SP147: Aging (2021) (0)
P37 Convergent somatic mutations in effectors of insulin signalling in chronic liver disease (2020) (0)
Supplementary file 6. (2014) (0)
The driver landscape of sporadic chordoma (2017) (0)
Author Correction: Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors (2019) (0)
FAT tumour suppressor gene is mutated by both homozygous deletion and point mutation in a variety of different cancer types (2008) (0)
Abstract 3967: The Cancer Genome Project high throughput analysis pipeline (2012) (0)
Combined Hardening of Composite Materials Based on Aluminum (2002) (0)
Mutations in FRMD7, a Novel Gene, Cause X-Linked Congenital Idiopathic Nystagmus (2007) (0)
SY-7-2 Oestrogen receptor mutations and variant forms (1996) (0)
Somatic variation in early development (2011) (0)
588 Exome Sequencing of Adenoid Cystic Carcinoma (2012) (0)
Murchison of an Ancient Cell Lineage Transmissable Dog Cancer Genome Reveals the Origin and History (2014) (0)
Publisher Correction: Genomic reconstruction of the SARS CoV-2 epidemic in England (2022) (0)
Abstract 4836: In vitro drug sensitivity testing along with full genome and transcriptome sequencing and phosphoproteomics: Comprehensive “next-generation” molecular oncology portrait of a sarcoma for facilitating treatment decisions (2011) (0)
Terminology for carcinoma-in-situ of the breast. (1996) (0)
Exploring the subclonal architecture of breast cancer (2012) (0)
Large scale immunoediting is not a hallmark of human melanoma (2016) (0)
792 The cancer cell line project – systematic resequencing of known cancer genes in over 750 cancer cell lines (2010) (0)
Poon Application as a Screening Tool Genome-Wide Mutational Signatures of Aristolochic Acid and Its (2013) (0)
Supplementary file 5. (2014) (0)
Abstract 2805: Exome sequencing identifies frequent mutation of the SWI/SNF complex genePBRM1in renal carcinoma (2011) (0)
Hunting for breast cancer genes (2006) (0)
Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors (2017) (0)
Genetic heterogeneity in familial Wilms tumour (1999) (0)
HRDetect : A mutational signature based predictor of BRCA 1 and BRCA 2 deficiency (2017) (0)
Mechanisms of activation and inactivation of dominant oncogenes and tumour suppressor genes (1996) (0)
Author Correction: Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors (2018) (0)
Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation (2019) (0)
4 High throughput genome sequencing for cancer gene discovery: BRAF and beyond (2004) (0)
Population dynamics of normal human blood inferred from somatic mutations (2018) (0)
Abstract IA36: Signatures of mutational processes (2016) (0)
Author Correction: Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro (2022) (0)
Extended Data Legend (2014) (0)
Molecular analyses of in situ breast cancer. (1993) (0)
Clonal Diaspora in Metastatic Esophageal Adenocarcinoma Describes a New Model of Cancer Progression (2018) (0)
167 Genomic characterisation of 1003 cancer cell-lines (2014) (0)
Bruges, a Record and an Impression (2010) (0)
Joyful Food. Spotlight: Physical Development. (2000) (0)
Book Reviews (2001) (0)
Abstract LB-161: Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells (2015) (0)
Comparative genomic hybridisation and next-generation sequencing: powerful tools to investigate chromosome number and structure in human embryos (2011) (0)
Abstract 611: AID/APOBEC cytidine deaminases can mimic the phenomenon of localized hypermutation in cancer orkataegis. (2013) (0)
1212 POSTER Testicular germ cell tumour and testicular microlithiasis; a familial association? (2007) (0)
Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data (2019) (0)
45 Use of somatically acquired genomic rearrangements as biomarkers in solid tumours (2010) (0)
Decoding the fine-scale structure of a breast cancer genome and data (2006) (0)
Author response: A proteomic chronology of gene expression through the cell cycle in human myeloid leukemia cells (2014) (0)
Abstract B022: Properties of T-cell-recognized neoantigens (2019) (0)
Wishing On A Star (2015) (0)
Barcoding of human haematopoietic stem and progenitor cells by whole genome sequencing reveals clonal dynamics of haematopoiesis (2017) (0)
The Genetics Feature Article of Familial Breast Cancer and Their Practical Implications (1994) (0)
1. The Genetics of Testicular Germ Cell Tumours (2002) (0)
gene MED12 missense mutation (p.N1007S) in the The original Lujan syndrome family has a novel (2008) (0)
Genome-wide screening for complete genetic loss in prostate cancer using cDNA microarrays (2003) (0)
Normal tissue clones preceding childhood kidney cancer (2019) (0)
Erratum: Identification and characterization of two novel JARID1C mutations: Suggestion of an emerging genotype-phenotype correlation (European Journal of Human Genetics (2010) 18 (330-335) DOI: 10.1038/ejhg.2009.175) (2012) (0)
462: Mutational characterisation of 400 breast cancers genomes (2014) (0)
Abstract 5142: COSMIC: Exploring the world's knowledge of somatic mutations in cancer. (2013) (0)
Genome‐Wide Searches for Mutations in Human Cancer (2005) (0)
Intra-tumour diversification in colorectal cancer at the single-cell level (2018) (0)
Recurrent intragenic rearrangements of EGFR and BRAF in soft tissue tumors of infants (2018) (0)
Initial Sequencing of Breast Cancer Genomes (2012) (0)
Abstract P6-08-10: Mutational signatures impact the breast cancer transcriptome and distinguish mitotic from immune response pathways (2016) (0)
Author Correction: Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors (2019) (0)
Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (2020) (0)
COLLECTED ABSTRACTS FIRST INTERNATIONAL WORKSHOP ON THE FUNCTION OF BRCAI AND BRCA2 (2014) (0)
Kataegis and other somatic mutational signatures in cancer (2013) (0)
ALTERED c-H-ras GENE IN NON-NEOPLASTIC TISSUE (1989) (0)
MSMA New Member Spotlight. (2020) (0)
Abstract 5143: From sequencing data to mutation spectra: a high throughput analysis pipeline. (2013) (0)
Mosaic DNMT3A Germline Mutation As a Model for Mutant DNMT3A Competitive Advantage in the Blood Lineage (2018) (0)
HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures (2017) (0)
Author Correction: Patterns of somatic structural variation in human cancer genomes (2020) (0)
COSMIC, curating the cancer variome (2008) (0)
Molecular biology for clinical oncologists. (1993) (0)
Abstract PL02-01: The pathogenesis of cancer susceptibility due to inherited DNA repair defects (2022) (0)
Author Correction: The evolutionary history of 2,658 cancers (2023) (0)
Title A mutational signature in gastric cancer suggests therapeuticstrategies (2015) (0)
Abstract 2973: Exome sequencing of 243 liver tumors identifies new mutational signatures and potential therapeutic targets (2015) (0)
Sequencing of Breast Cancer Genomes. (2009) (0)
Session 3 S6. The cancer genome project (2002) (0)

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