Michal Hocek
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Czech chemist
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Michal Hocekchemistry Degrees
Chemistry
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Organic Chemistry
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Chemistry
Michal Hocek's Degrees
- PhD Chemistry Charles University
- Masters Chemistry Charles University
- Bachelors Chemistry Charles University
Why Is Michal Hocek Influential?
(Suggest an Edit or Addition)According to Wikipedia, Michal Hocek is a Czech chemist. He is a group leader at the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and a professor of organic chemistry at Charles University in Prague. He specializes in the chemistry and chemical biology of nucleosides, nucleotides, and nucleic acids.
Michal Hocek's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- C-nucleosides: synthetic strategies and biological applications. (2009) (235)
- Synthesis and cytostatic activity of substituted 6-phenylpurine bases and nucleosides: application of the Suzuki-Miyaura cross-coupling reactions of 6-chloropurine derivatives with phenylboronic acids. (2000) (173)
- Cytostatic 6-arylpurine nucleosides. 6. SAR in anti-HCV and cytostatic activity of extended series of 6-hetarylpurine ribonucleosides. (2005) (125)
- Cross-coupling reactions of nucleoside triphosphates followed by polymerase incorporation. Construction and applications of base-functionalized nucleic acids. (2008) (119)
- An efficient method for the construction of functionalized DNA bearing amino acid groups through cross-coupling reactions of nucleoside triphosphates followed by primer extension or PCR. (2007) (119)
- Nucleobase modification as redox DNA labelling for electrochemical detection. (2011) (118)
- Aminophenyl- and nitrophenyl-labeled nucleoside triphosphates: synthesis, enzymatic incorporation, and electrochemical detection. (2008) (115)
- Synthesis of base-modified 2'-deoxyribonucleoside triphosphates and their use in enzymatic synthesis of modified DNA for applications in bioanalysis and chemical biology. (2014) (113)
- Syntheses of Purines Bearing Carbon Substituents in Positions 2, 6 or 8 by Metal- or Organometal-Mediated C−C Bond-Forming Reactions (2003) (110)
- Ferrocenylethynyl derivatives of nucleoside triphosphates: synthesis, incorporation, electrochemistry, and bioanalytical applications. (2007) (105)
- Cross-coupling reactions of unprotected halopurine bases, nucleosides, nucleotides and nucleoside triphosphates with 4-boronophenylalanine in water. Synthesis of (purin-8-yl)- and (purin-6-yl)phenylalanines. (2006) (97)
- Direct C-H arylation of purines: development of methodology and its use in regioselective synthesis of 2,6,8-trisubstituted purines. (2006) (96)
- A Rotational BODIPY Nucleotide: An Environment-Sensitive Fluorescence-Lifetime Probe for DNA Interactions and Applications in Live-Cell Microscopy. (2015) (93)
- Direct polymerase synthesis of reactive aldehyde-functionalized DNA and its conjugation and staining with hydrazines. (2010) (91)
- Base-modified DNA labeled by [Ru(bpy)(3)](2+) and [Os(bpy)(3)](2+) complexes: construction by polymerase incorporation of modified nucleoside triphosphates, electrochemical and luminescent properties, and applications. (2009) (90)
- Synthesis and significant cytostatic activity of 7-hetaryl-7-deazaadenosines. (2011) (87)
- Cytostatic 6-Arylpurine Nucleosides III. Synthesis and Structure-Activity Relationship Study in Cytostatic Activity of 6-Aryl-, 6-Hetaryl- and 6-Benzylpurine Ribonucleosides (2001) (81)
- Synthesis and photophysical properties of biaryl-substituted nucleos(t)ides. Polymerase synthesis of DNA probes bearing solvatochromic and pH-sensitive dual fluorescent and 19F NMR labels. (2012) (74)
- Synthesis of aldehyde-linked nucleotides and DNA and their bioconjugations with lysine and peptides through reductive amination. (2012) (68)
- 6-(Het)aryl-7-deazapurine ribonucleosides as novel potent cytostatic agents. (2010) (66)
- Vinylsulfonamide and acrylamide modification of DNA for cross-linking with proteins. (2013) (66)
- An efficient synthesis of 2-substituted 6-methylpurine bases and nucleosides by Fe- or Pd-catalyzed cross-coupling reactions of 2,6-dichloropurines. (2003) (65)
- GFP-like fluorophores as DNA labels for studying DNA-protein interactions. (2012) (65)
- Labelling of nucleosides and oligonucleotides by solvatochromic 4-aminophthalimide fluorophore for studying DNA–protein interactions (2012) (65)
- Synthesis of 6,8,9-tri- and 2,6,8,9-tetrasubstituted purines by a combination of the Suzuki cross-coupling, N-arylation, and direct C-H arylation reactions. (2008) (59)
- Pyrrolo[2,3‐d]pyrimidine (7‐deazapurine) as a privileged scaffold in design of antitumor and antiviral nucleosides (2017) (58)
- Systematic exploration of a class of hydrophobic unnatural base pairs yields multiple new candidates for the expansion of the genetic alphabet (2014) (57)
- Modular and practical synthesis of 6-substituted pyridin-3-yl C-nucleosides. (2007) (54)
- The Suzuki-Miyaura Cross-Coupling Reactions of 2-, 6- or 8-Halopurines with Boronic Acids Leading to 2-, 6- or 8-Aryl- and -Alkenylpurine Derivatives (2001) (53)
- Anthraquinone as a redox label for DNA: synthesis, enzymatic incorporation, and electrochemistry of anthraquinone-modified nucleosides, nucleotides, and DNA. (2011) (53)
- Synthesis, cytostatic, antimicrobial, and anti-HCV activity of 6-substituted 7-(het)aryl-7-deazapurine ribonucleosides. (2014) (53)
- Regioselective direct C-H arylations of protected uracils. Synthesis of 5- and 6-aryluracil bases. (2011) (53)
- 7-Aryl-7-deazaadenine 2'-deoxyribonucleoside triphosphates (dNTPs): better substrates for DNA polymerases than dATP in competitive incorporations. (2014) (52)
- Intramolecular direct C-H arylation approach to fused purines. Synthesis of purino[8,9-f]phenanthridines and 5,6-dihydropurino[8,9-a]isoquinolines. (2010) (52)
- Direct C-H sulfenylation of purines and deazapurines. (2013) (52)
- Cleavage of adenine-modified functionalized DNA by type II restriction endonucleases (2009) (52)
- Ferrocene-modified purines as potential electrochemical markers: synthesis, crystal structures, electrochemistry and cytostatic activity of (ferrocenylethynyl)- and (ferrocenylethyl)purines. (2004) (51)
- The first direct C-H arylation of purine nucleosides. (2007) (49)
- 5-Substituted Pyrimidine and 7-Substituted 7-Deazapurine dNTPs as Substrates for DNA Polymerases in Competitive Primer Extension in the Presence of Natural dNTPs. (2016) (49)
- The Suzuki-Miyaura Cross-Coupling Reactions of 6-Halopurines with Boronic Acids Leading to 6-Aryl- and 6-Alkenylpurines (1999) (47)
- Transient and switchable (triethylsilyl)ethynyl protection of DNA against cleavage by restriction endonucleases. (2011) (47)
- Effect of spin-orbit coupling on reduction potentials of octahedral ruthenium(II/III) and osmium(II/III) complexes. (2008) (47)
- Enzymatic Synthesis of Base-Functionalized Nucleic Acids for Sensing, Cross-linking, and Modulation of Protein-DNA Binding and Transcription. (2019) (46)
- Cleavage of Functionalized DNA Containing 5‐Modified Pyrimidines by Type II Restriction Endonucleases (2011) (46)
- Tail-labelling of DNA probes using modified deoxynucleotide triphosphates and terminal deoxynucleotidyl transferase. Application in electrochemical DNA hybridization and protein-DNA binding assays. (2011) (46)
- Benzofurazane as a new redox label for electrochemical detection of DNA: towards multipotential redox coding of DNA bases. (2013) (45)
- 2‐Substituted dATP Derivatives as Building Blocks for Polymerase‐Catalyzed Synthesis of DNA Modified in the Minor Groove (2016) (44)
- Direct determination of tautomerism in purine derivatives by low-temperature NMR spectroscopy (2004) (42)
- Scope and limitations of the nicking enzyme amplification reaction for the synthesis of base-modified oligonucleotides and primers for PCR. (2013) (42)
- Understanding the NMR chemical shifts for 6-halopurines: role of structure, solvent and relativistic effects. (2010) (40)
- Synthesis of nucleoside and nucleotide conjugates of bile acids, and polymerase construction of bile acid-functionalized DNA. (2010) (40)
- Synthesis of C-aryldeoxyribosides by [2 + 2 + 2]-cyclotrimerization catalyzed by Rh, Ni, Co, and Ru complexes. (2006) (40)
- Human DNA polymerase alpha uses a combination of positive and negative selectivity to polymerize purine dNTPs with high fidelity. (2006) (40)
- Synthesis of 2'-deoxyadenosine nucleosides bearing bipyridine-type ligands and their Ru-complexes in position 8 through cross-coupling reactions. (2007) (39)
- Purines Bearing Phenanthroline or Bipyridine Ligands and Their RuII Complexes in Position 8 as Model Compounds for Electrochemical DNA Labeling – Synthesis, Crystal Structure, Electrochemistry, Quantum Chemical Calculations, Cytostatic and Antiviral Activity (2007) (39)
- Cytostatic and antiviral 6-arylpurine ribonucleosides. Part 7: synthesis and evaluation of 6-substituted purine l-ribonucleosides. (2006) (39)
- Synthesis and antiviral activity of 4,6-disubstituted pyrimido[4,5-b]indole ribonucleosides. (2012) (39)
- Synthesis and photophysical properties of 7-deaza-2'-deoxyadenosines bearing bipyridine ligands and their Ru(II)-complexes in position 7. (2008) (38)
- Polymerase synthesis of photocaged DNA resistant against cleavage by restriction endonucleases. (2014) (38)
- Direct C-H borylation and C-H arylation of pyrrolo[2,3-d]pyrimidines: synthesis of 6,8-disubstituted 7-deazapurines. (2009) (38)
- Synthesis of 8-bromo-, 8-methyl- and 8-phenyl-dATP and their polymerase incorporation into DNA. (2008) (37)
- Facile and efficient synthesis of 6-(hydroxymethyl)purines. (2004) (37)
- Synthesis of enantiomerically pure (purin-6-yl)phenylalanines and their nucleosides, a novel type of purine-amino acid conjugates. (2005) (37)
- Switching the Regioselectivity of Direct C–H Arylation of 1,3‐Dimethyluracil (2009) (36)
- Synthesis of carba-analogues of myoseverin by regioselective cross-coupling reactions of 2,6-dichloro-9-isopropylpurine (2003) (35)
- Bodipy-labeled nucleoside triphosphates for polymerase synthesis of fluorescent DNA. (2014) (35)
- Polymerase synthesis of DNA labelled with benzylidene cyanoacetamide-based fluorescent molecular rotors: fluorescent light-up probes for DNA-binding proteins. (2015) (34)
- Dichotomy in Regioselective Cross-Coupling Reactions of 6,8-Dichloropurines with Phenylboronic Acid and Methylmagnesium Chloride: Synthesis of 6,8-Disubstituted Purines (2004) (33)
- Alkylsulfanylphenyl derivatives of cytosine and 7-deazaadenine nucleosides, nucleotides and nucleoside triphosphates: synthesis, polymerase incorporation to DNA and electrochemical study. (2011) (33)
- CycloSal‐phosphate Pronucleotides of Cytostatic 6‐(Het)aryl‐7‐deazapurine Ribonucleosides: Synthesis, Cytostatic Activity, and Inhibition of Adenosine Kinases (2010) (33)
- Synthesis of Acyclic Nucleotide Analogues Derived from 2-Amino-6- C -substituted Purines via Cross-Coupling Reactions of 2-Amino-9-{2-[(diisopropoxyphosphoryl)methoxy]ethyl}-6-halopurines with Diverse Organometallic Reagents (2000) (32)
- Regioselectivity in Cross-Coupling Reactions of 2,6,8-Trichloro-9-(tetrahydropyran-2-yl)purine: Synthesis of 2,6,8-Trisubstituted Purine Bases (2004) (32)
- New modular and efficient approach to 6-substituted pyridin-2-yl C-nucleosides. (2006) (32)
- The first synthesis and cytostatic activity of novel 6-(fluoromethyl)purine bases and nucleosides. (2005) (31)
- Synthesis of acetylene linked double-nucleobase nucleos(t)ide building blocks and polymerase construction of DNA containing cytosines in the major groove. (2011) (30)
- Synthesis and cytostatic activity of nucleosides and acyclic nucleoside analogues derived from 6-(trifluoromethyl)purines (1999) (30)
- Cytostatic 6-Arylpurine Nucleosides II. Synthesis of Sugar-Modified Derivatives: 9-(2-Deoxy-β-D- erythro -pentofuranosyl)-, 9-(5-Deoxy-β-D-ribofuranosyl)- and 9-(2,3-Dihydroxypropyl)-6-phenylpurines (2000) (30)
- Reactive modifications of DNA nucleobases for labelling, bioconjugations, and cross-linking. (2019) (29)
- Aqueous Heck cross-coupling preparation of acrylate-modified nucleotides and nucleoside triphosphates for polymerase synthesis of acrylate-labeled DNA. (2013) (29)
- Covalent analogues of DNA base-pairs and triplets. Part 2: synthesis and cytostatic activity of bis(purin-6-yl)acetylenes,-diacetylenes and related compounds. (2002) (29)
- A New Modular and Practical Methodology for the Synthesis of 4‐ or 3‐Substituted Phenyl C‐Nucleosides (2005) (29)
- Co- and homocyclotrimerization reactions of protected 1-alkynyl-2-deoxyribofuranose. Synthesis of C-nucleosides, C-di- and C-trisaccharide analogues (2008) (28)
- Polymerase Synthesis and Restriction Enzyme Cleavage of DNA Containing 7‐Substituted 7‐Deazaguanine Nucleobases (2015) (27)
- Strategies toward protecting group-free glycosylation through selective activation of the anomeric center (2017) (27)
- CYTOSTATIC 6-ARYLPURINE NUCLEOSIDES IV + . SYNTHESIS OF 2-SUBSTITUTED 6-PHENYLPURINE RIBONUCLEOSIDES (2002) (27)
- Direct One-Pot Synthesis of Nucleosides from Unprotected or 5-O-Monoprotected D-Ribose. (2015) (27)
- Interpretation of indirect nuclear spin-spin couplings in isomers of adenine: novel approach to analyze coupling electron deformation density using localized molecular orbitals. (2010) (26)
- Switching transcription with bacterial RNA polymerase through photocaging, photorelease and phosphorylation reactions in the major groove of DNA† †Electronic supplementary information (ESI) available: Contains detailed experimental procedures, characterization data and additional figures and gels. S (2019) (26)
- Interpretation of substituent effects on 13C and 15N NMR chemical shifts in 6-substituted purines. (2011) (26)
- Structural basis for inhibition of mycobacterial and human adenosine kinase by 7-substituted 7-(Het)aryl-7-deazaadenine ribonucleosides. (2014) (25)
- Synthesis and Cytostatic and Antiviral Profiling of Thieno-Fused 7-Deazapurine Ribonucleosides. (2017) (25)
- Polymerase synthesis of oligonucleotides containing a single chemically modified nucleobase for site-specific redox labelling. (2013) (25)
- Cocyclotrimerization of 6-Alkynylpurines with α,ω-Diynes as a Novel Approach to Biologically Active 6-Arylpurines (2004) (25)
- Sugar-modified derivatives of cytostatic 7-(het)aryl-7-deazaadenosines: 2'-C-methylribonucleosides, 2'-deoxy-2'-fluoroarabinonucleosides, arabinonucleosides and 2'-deoxyribonucleosides. (2012) (25)
- Synthesis of 2-Substituted 6-(Hydroxymethyl)purine Bases and Nucleosides (2005) (24)
- Herpes simplex virus-1 DNA primase: a remarkably inaccurate yet selective polymerase. (2009) (23)
- Optimization of the Pyridyl Nucleobase Scaffold for Polymerase Recognition and Unnatural Base Pair Replication (2008) (23)
- A facile and efficient synthesis of (Purin-6-yl)alanines. (2004) (23)
- Phosphoramidate pronucleotides of cytostatic 6-aryl-7-deazapurine ribonucleosides. (2011) (23)
- Preparation of short cytosine-modified oligonucleotides by nicking enzyme amplification reaction. (2012) (23)
- Furan-oxidation-triggered inducible DNA cross-linking: acyclic versus cyclic furan-containing building blocks--on the benefit of restoring the cyclic sugar backbone. (2011) (23)
- [2+2+2]-Co-cyclotrimerization 6-alkynylpurines with diynes: a method for preparation of 6-arylpurines (2003) (23)
- Synthesis and Antiviral Activity of Acyclic Nucleotide Analogues Derived from 6-(Aminomethyl)purines and Purine-6-carboxamidines (1996) (23)
- Inhibition of non-templated nucleotide addition by DNA polymerases in primer extension using twisted intercalating nucleic acid modified templates. (2016) (23)
- Synthesis of Nucleosides through Direct Glycosylation of Nucleobases with 5-O-Monoprotected or 5-Modified Ribose: Improved Protocol, Scope, and Mechanism. (2017) (22)
- Tetrathiafulvalene-Labelled Nucleosides and Nucleoside Triphosphates: Synthesis, Electrochemistry and the Scope of Their Polymerase Incorporation into DNA (2009) (22)
- Synthesis of Hydrazone‐Modified Nucleotides and Their Polymerase Incorporation onto DNA for Redox Labeling (2012) (21)
- Synthesis and biological activity of benzo-fused 7-deazaadenosine analogues. 5- and 6-substituted 4-amino- or 4-alkylpyrimido[4,5-b]indole ribonucleosides. (2013) (21)
- Chloroacetamide-Linked Nucleotides and DNA for Cross-Linking with Peptides and Proteins. (2016) (21)
- A modular approach to aryl-C-ribonucleosides via the allylic substitution and ring-closing metathesis sequence. a stereocontrolled synthesis of all four α-/β- and D-/L-C-nucleoside stereoisomers. (2011) (21)
- Synthesis of 2,4‐Disubstituted Pyrimidin‐5‐yl C‐2′‐Deoxyribonucleosides by Sequential Regioselective Reactions of 2,4‐Dichloropyrimidine Nucleosides (2010) (21)
- Tuning of Oxidation Potential of Ferrocene for Ratiometric Redox Labeling and Coding of Nucleotides and DNA (2019) (21)
- Mechanisms by which human DNA primase chooses to polymerize a nucleoside triphosphate. (2010) (21)
- A Facile Synthesis of 6-Cyanopurine Bases (1995) (21)
- Highly Methylated Purines and Purinium Salts as Analogues of Heteromines (2005) (20)
- Perfluoroalkylation of 6-Iodopurines by Trimethyl(perfluoroalkyl)silanes. Synthesis of 6-(Perfluoroalkyl)purine Bases, Nucleosides and Acyclic Nucleotide Analogues (1999) (20)
- A general and efficient synthesis of pyridin-2-yl C-ribonucleosides bearing diverse alkyl, aryl, amino, and carbamoyl groups in position 6. (2010) (20)
- Preparation of highly substituted 6-arylpurine ribonucleosides by Ni-catalyzed cyclotrimerization. Scope of the reaction. (2006) (20)
- Synthesis of (purin-6-yl)acetates and 6-(2-hydroxyethyl)purines via cross-couplings of 6-chloropurines with the Reformatsky reagent (2007) (19)
- Synthesis of Purines Bearing Functionalized C‐Substituents by the Conjugate Addition of Nucleophiles to 6‐Vinylpurines and 6‐Ethynylpurines (2006) (19)
- Synthesis, cytostatic and anti-HCV activity of 6-(N-substituted aminomethyl)-, 6-(O-substituted hydroxymethyl)- and 6-(S-substituted sulfanylmethyl)purine nucleosides. (2008) (19)
- Synthesis of Acyclic Nucleotide Analogues Derived from 6-Hetarylpurines via Cross-Coupling Reactions of 9-[2-(Diethoxyphosphonylmethoxy)ethyl]-6-iodopurine with Hetaryl Organometallic Reagents (1997) (19)
- 7-(2-Thienyl)-7-Deazaadenosine (AB61), a New Potent Nucleoside Cytostatic with a Complex Mode of Action (2016) (19)
- CYTOSTATIC 6-ARYLPURINE NUCLEOSIDES V. + SYNTHESIS OF 8-SUBSTITUTED 6-PHENYLPURINE RIBONUCLEOSIDES (2003) (19)
- Modular synthesis of 5-substituted thiophen-2-yl C-2'-deoxyribonucleosides. (2008) (18)
- Exceptional thermodynamic stability of DNA duplexes modified by nonpolar base analogues is due to increased stacking interactions and favorable solvation: Correlated ab initio calculations and molecular dynamics simulations. (2006) (18)
- C-H Phosphonation of Pyrrolopyrimidines: Synthesis of Substituted 7- and 9-Deazapurine-8-phosphonate Derivatives. (2016) (18)
- Cobalt‐Induced Synthesis of 6‐(Pyridin‐2‐yl)purines by Microwave‐Enhanced [2+2+2] Cyclotrimerization (2008) (18)
- Squaramate‐Modified Nucleotides and DNA for Specific Cross‐Linking with Lysine‐Containing Peptides and Proteins (2019) (18)
- Synthesis of acyclic nucleotide analogues derived from N-substituted 6-(1-aminoethyl)purines via 6-acetylpurine derivatives (1997) (18)
- Brightly Fluorescent 2'-Deoxyribonucleoside Triphosphates Bearing Methylated Bodipy Fluorophore for in Cellulo Incorporation to DNA, Imaging, and Flow Cytometry. (2018) (18)
- Synthesis of Protected (Purin-6-yl)glycines via Pd-Catalyzed a-Arylation of Ethyl N-(Diphenylmethylidene)glycinate with 6-Iodopurines (2004) (18)
- Synthesis of benzamide-C-ribonucleosides by Pd-catalyzed aminocarbonylations (2009) (18)
- Covalent Analogues of DNA Base-Pairs and Triplets V. Synthesis of Purine-Purine and Purine-Pyrimidine Conjugates Connected by Diverse Types of Acyclic Carbon Linkages (2002) (18)
- Carborane- or Metallacarborane-Linked Nucleotides for Redox Labeling. Orthogonal Multipotential Coding of all Four DNA Bases for Electrochemical Analysis and Sequencing. (2021) (17)
- Azidopropylvinylsulfonamide as a New Bifunctional Click Reagent for Bioorthogonal Conjugations: Application for DNA-Protein Cross-Linking. (2015) (17)
- Turning Off Transcription with Bacterial RNA Polymerase through CuAAC Click Reactions of DNA Containing 5-Ethynyluracil. (2018) (17)
- Electrochemical genosensor for the direct detection of tailed PCR amplicons incorporating ferrocene labelled dATP. (2019) (17)
- Flexible Alkyne-Linked Thymidine Phosphoramidites and Triphosphates for Chemical or Polymerase Synthesis and Fast Postsynthetic DNA Functionalization through Copper-Catalyzed Alkyne-Azide 1,3-Dipolar Cycloaddition. (2018) (17)
- Nucleobase Protection Strategy for Gene Cloning and Expression (2013) (17)
- Redox Labels and Indicators Based on Transition Metals and Organic Electroactive Moieties for Electrochemical Nucleic Acids Sensing (2011) (17)
- Synthesis of nucleoside mono- and triphosphates bearing oligopyridine ligands, their incorporation into DNA and complexation with transition metals. (2012) (16)
- A Modular Methodology for the Synthesis of 4‐ and 3‐Substituted Benzene and Aniline C‐Ribonucleosides (2008) (16)
- General and modular synthesis of isomeric 5-substituted pyridin-2-yl and 6-substituted pyridin-3-yl C-ribonucleosides bearing diverse alkyl, aryl, hetaryl, amino, carbamoyl, and hydroxy groups. (2011) (16)
- Synthesis, cytostatic, and antiviral activity of novel 6-[2-(dialkylamino)ethyl]-, 6-(2-alkoxyethyl)-, 6-[2-(alkylsulfanyl)ethyl]-, and 6-[2-(dialkylamino)vinyl]purine nucleosides. (2008) (16)
- 6-Alkyl-, 6-aryl- or 6-hetaryl-7-deazapurine ribonucleosides as inhibitors of human or MTB adenosine kinase and potential antimycobacterial agents (2013) (16)
- Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides. (2018) (16)
- Modular Synthesis of 5‐Substituted Furan‐2‐yl C‐2′‐Deoxyribonucleosides and Biaryl Covalent Base‐Pair Analogues (2010) (15)
- Synthesis of Dihydroxyalkynyl and Dihydroxyalkyl Nucleotides as Building Blocks or Precursors for Introduction of Diol or Aldehyde Groups to DNA for Bioconjugations. (2018) (15)
- Cyclotrimerization of 6-ethynylpurines. Synthesis of 1,2,4- and 1,3,5-tris(purin-6-yl)benzenes as novel Hoogsteen-triplet analogues (2001) (15)
- 2‐Allyl‐ and Propargylamino‐dATPs for Site‐Specific Enzymatic Introduction of a Single Modification in the Minor Groove of DNA (2018) (14)
- Covalent Analogues of DNA Base-Pairs and Triplets IV. Synthesis of Trisubstituted Benzenes Bearing Purine and/or Pyrimidine Rings by Cyclotrimerization of 6-Ethynylpurines and/or 5-Ethynyl-1,3-dimethyluracil (2002) (14)
- Sugar-modified derivatives of cytostatic 6-(het)aryl-7-deazapurine nucleosides: 2′-C-methylribonucleosides, arabinonucleosides and 2′-deoxy-2′-fluoroarabinonucleosides (2011) (14)
- Modification of Pyrrolo[2,3‐d]pyrimidines by C–H Borylation Followed by Cross‐Coupling or Other Transformations: Synthesis of 6,8‐Disubstituted 7‐Deazapurine Bases (2015) (14)
- Chemoselective Synthesis of 4,5‐Diarylpyrrolo[2,3‐d]pyrimidines (6,7‐Diaryl‐7‐deazapurines) by Consecutive Suzuki and Liebeskind–Srogl Cross‐Couplings (2014) (14)
- Protected 5-(hydroxymethyl)uracil nucleotides bearing visible-light photocleavable groups as building blocks for polymerase synthesis of photocaged DNA. (2018) (14)
- Synthesis and Cytostatic and Antiviral Activities of 2′‐Deoxy‐2′,2′‐difluororibo‐ and 2′‐Deoxy‐2′‐fluororibonucleosides Derived from 7‐(Het)aryl‐7‐deazaadenines (2013) (14)
- Synthesis of 2,6-disubstituted pyridin-3-yl C-2'-deoxyribonucleosides through chemoselective transformations of bromo-chloropyridine C-nucleosides. (2013) (14)
- Influence of major-groove chemical modifications of DNA on transcription by bacterial RNA polymerases (2016) (14)
- Cytostatic and Antiviral 6-Arylpurine Ribonucleosides IX. Synthesis and Evaluation of 6-Substituted 3-Deazapurine Ribonucleosides (2008) (13)
- Covalent analogues of DNA base-pairs and triplets. Part 3: Synthesis of 1,4- and 1,3-bis(purin-6-yl)benzenes and 1-(1,3-dimethyluracil-5-yl)-3 or 4-(purin-9-yl)benzenes ☆ (2002) (13)
- Electrochemical behaviour of 2,4-dinitrophenylhydrazi(o)ne as multi-redox centre DNA label at mercury meniscus modified silver solid amalgam electrode (2014) (13)
- Electrochemical behaviour of 2,4-dinitrophenylhydrazi(o)ne as multi-redox centre DNA label at mercury meniscus modified silver solid amalgam electrode (2014) (13)
- B family DNA polymerases asymmetrically recognize pyrimidines and purines. (2011) (13)
- Methoxyphenol and Dihydrobenzofuran as Oxidizable Labels for Electrochemical Detection of DNA (2014) (13)
- Polymerase Synthesis of DNAs Bearing Vinyl Groups in the Major Groove and their Cleavage by Restriction Endonucleases (2014) (13)
- Flexible double-headed cytosine-linked 2'-deoxycytidine nucleotides. Synthesis, polymerase incorporation to DNA and interaction with DNA methyltransferases. (2016) (12)
- Enzymatic synthesis of base-modified RNA by T7 RNA polymerase. A systematic study and comparison of 5-substituted pyrimidine and 7-substituted 7-deazapurine nucleoside triphosphates as substrates. (2018) (12)
- Protected 2'-deoxyribonucleoside triphosphate building blocks for the photocaging of epigenetic 5-(hydroxymethyl)cytosine in DNA. (2018) (12)
- Antiviral Activity of 7-Substituted 7-Deazapurine Ribonucleosides, Monophosphate Prodrugs, and Triphoshates against Emerging RNA Viruses. (2021) (12)
- 5-(Hydroxymethyl)uracil and -cytosine as potential epigenetic marks enhancing or inhibiting transcription with bacterial RNA polymerase. (2017) (12)
- Synthesis of 2′-deoxy-2′-fluororibo- and 2′-deoxy-2′,2′-difluororibonucleosides derived from 6-(het)aryl-7-deazapurines (2012) (12)
- Sonogashira reactions of α- and β-1-ethynyl-2-deoxyribosides: synthesis of acetylene-extended C-nucleosides (2010) (11)
- Voltammetric Study of dsDNA Modified by Multi-redox Label Based on N-methyl-4-hydrazino-7-nitrobenzofurazan (2014) (11)
- Additions of Thiols to 7-Vinyl-7-deazaadenine Nucleosides and Nucleotides. Synthesis of Hydrophobic Derivatives of 2'-Deoxyadenosine, dATP and DNA. (2016) (11)
- Voltammetric Study of dsDNA Modified by Multi-redox Label Based on N-methyl-4-hydrazino-7-nitrobenzofurazan (2014) (11)
- Modular synthesis of 1-α- and 1-β-(indol-2-yl)-2'-deoxyribose C-nucleosides. (2011) (11)
- COVALENT ANALOGUES OF DNA BASE-PAIRS AND TRIPLETS VII. + SYNTHESIS AND CYTOSTATIC ACTIVITY OF BIS(PURIN-6-YL)ACETYLENE AND -DIACETYLENE NUCLEOSIDES (2004) (11)
- Nucleotide‐Bearing Benzylidene‐Tetrahydroxanthylium Near‐IR Fluorophore for Sensing DNA Replication, Secondary Structures and Interactions (2020) (11)
- Synthesis of substituted 6-cyclopropylpurine bases and nucleosides by cross-coupling reactions or cyclopropanations. (2008) (11)
- Synthesis of (purin-6-yl)methylphosphonate bases and nucleosides (2010) (10)
- Synthesis of Fluorescent 2-Substituted 6-(Het)aryl-7-deazapurine Bases {4-(Het)aryl-pyrrolo[2,3-d]pyrimidines} by Aqueous Suzuki–Miyaura Cross-Coupling Reactions (2016) (10)
- Carborane-linked 2'-deoxyuridine 5'-O-triphosphate as building block for polymerase synthesis of carborane-modified DNA. (2017) (10)
- Synthesis of 6-Amino-, 6-Methyl- and 6-Aryl-2-(hydroxymethyl)purine Bases and Nucleosides (2006) (10)
- Direct C–H amination and C–H chloroamination of 7-deazapurines (2014) (10)
- Trifluoroacetophenone-Linked Nucleotides and DNA for Studying of DNA-Protein Interactions by 19F NMR Spectroscopy. (2017) (10)
- Acetophenyl-thienyl-aniline-linked nucleotide for construction of solvatochromic fluorescence light-up DNA probes sensing protein-DNA interactions. (2021) (10)
- A General Regioselective Synthesis of 2,4-Diarylpyrimidines from 2- Thiouracil through Two Orthogonal Cross-Coupling Reactions (2012) (9)
- 2‐Substituted 6‐(Het)aryl‐7‐deazapurine Ribonucleosides: Synthesis, Inhibition of Adenosine Kinases, and Antimycobacterial Activity (2015) (9)
- Isomeric Naphtho‐Fused 7‐Deazapurine Nucleosides and Nucleotides: Synthesis, Biological Activity, Photophysical Properties and Enzymatic Incorporation to Nucleic Acids (2018) (9)
- Voltammetric and adsorption study of 4-nitrophenyl-triazole-labeled 2′-deoxycytidine and 7-deazaadenosine nucleosides at boron-doped diamond electrode (2018) (9)
- Synthesis of 2′-deoxycytidine and its triphosphate bearing tryptophan-based imidazolinone fluorophore for environment sensitive fluorescent labelling of DNA (2018) (9)
- Synthesis of diverse 6-(1,2-disubstituted ethyl)purine bases and nucleosides via 6-(oxiran-2-yl)purines (2008) (9)
- Synthesis of nucleosides and dNTPs bearing oligopyridine ligands linked through an octadiyne tether, their incorporation into DNA and complexation with transition metal cations. (2013) (9)
- Cytostatic and Antiviral 6-Arylpurine Ribonucleosides VIII. Synthesis and Evaluation of 6-Substituted Purine 3'-Deoxyribonucleosides (2006) (9)
- Synthesis and cytostatic activity of 7-arylsulfanyl-7-deazapurine bases and ribonucleosides (2015) (9)
- Oxidative DNA Cleavage with Clip‐Phenanthroline Triplex‐Forming Oligonucleotide Hybrids (2020) (9)
- Thiophene-linked tetramethylbodipy-labeled nucleotide for viscosity-sensitive oligonucleotide probes of hybridization and protein-DNA interactions. (2020) (9)
- Synthesis and biological profiling of 6- or 7-(het)aryl-7-deazapurine 4'-C-methylribonucleosides. (2015) (9)
- Enzymatic synthesis of hypermodified DNA polymers for sequence-specific display of four different hydrophobic groups (2020) (9)
- Innentitelbild: A Rotational BODIPY Nucleotide: An Environment‐Sensitive Fluorescence‐Lifetime Probe for DNA Interactions and Applications in Live‐Cell Microscopy (Angew. Chem. 1/2016) (2016) (8)
- Fluorescence quenching in oligonucleotides containing 7-substituted 7-deazaguanine bases prepared by the nicking enzyme amplification reaction. (2015) (8)
- Synthesis of 6-Substituted 2(1H)-Pyridon-3-yl C-2′-Deoxyribonucleosides (2012) (8)
- Novel Method for Preparation of Highly Substituted 6-Arylpurines by Reactions of 6-Alkynylpurines with Zirconacyclopentadienes (2005) (8)
- C–H Imidation of 7-Deazapurines (2018) (8)
- Synthesis of Benzene and Pyridine 2′- C -Methyl- C -ribonucleosides and -nucleotides (2015) (8)
- Duplex Electrochemical DNA Sensor to Detect Bacillus anthracis CAP and PAG DNA Targets Based on the Incorporation of Tailed Primers and Ferrocene-Labeled dATP (2019) (8)
- Cross-Coupling Reactions ofHalopurines with Aryl- and Alkyltrifluoroborates; TheScope and Limitations in the Synthesis of Modified Purines (2009) (8)
- Ir-catalyzed C–H silylations of phenyldeazapurines (2015) (8)
- Innentitelbild: A Rotational BODIPY Nucleotide: An Environment‐Sensitive Fluorescence‐Lifetime Probe for DNA Interactions and Applications in Live‐Cell Microscopy (Angew. Chem. 1/2016) (2016) (8)
- Copper-mediated arylsulfanylations and arylselanylations of pyrimidine or 7-deazapurine nucleosides and nucleotides. (2016) (8)
- 6-Aryl-4-amino-pyrimido[4,5-b]indole 2'-deoxyribonucleoside triphosphates (benzo-fused 7-deaza-dATP analogues): Synthesis, fluorescent properties, enzymatic incorporation into DNA and DNA-protein binding study. (2016) (7)
- Voltammetric analysis of 5-(4-Azidophenyl)-2′-deoxycytidine nucleoside and azidophenyl-labelled single- and double-stranded DNAs (2016) (7)
- A General Regioselective Approachto 2,4-Disubstituted Pyrimidin-5-yl C-2-Deoxyribonucleosides (2012) (7)
- Synthesis of 6‐(4,5‐Dihydrofuran‐2‐yl)‐ and 6‐(Tetrahydrofuran‐2‐yl)purine Bases and Nucleosides (2008) (7)
- Voltammetric analysis of 5-(4-Azidophenyl)-2′-deoxycytidine nucleoside and azidophenyl-labelled single- and double-stranded DNAs (2016) (7)
- Phenothiazine-linked nucleosides and nucleotides for redox labelling of DNA. (2017) (7)
- Synthesis and Cytotoxic and Antiviral Activity Profiling of All-Four Isomeric Series of Pyrido-Fused 7-Deazapurine Ribonucleosides. (2020) (6)
- Synthesis of 2′-Deoxyuridineand 2′-Deoxycytidine Nucleosides Bearing Bipyridineand Terpyridine Ligands at Position 5 (2009) (6)
- SYNTHESIS OF ACYCLIC NUCLEOTIDE ANALOGUES DERIVED FROM 2-(AMINOMETHYL)ADENINE AND 2-(AMINOMETHYL)HYPOXANTHINE (1995) (6)
- 2-Substituted 2'-deoxyinosine 5'-triphosphates as substrates for polymerase synthesis of minor-groove-modified DNA and effects on restriction endonuclease cleavage. (2019) (6)
- Aqueous-phase suzuki-miyaura cross-coupling reactions of free halopurine bases (2006) (6)
- Synthesis and Cytostatic Activity of Novel 6-(Difluoromethyl)purine Bases and Nucleosides (2006) (6)
- 2-Formyl-dATP as Substrate for Polymerase Synthesis of Reactive DNA Bearing an Aldehyde Group in the Minor Groove. (2020) (6)
- Cross‐Coupling Modification of Nucleoside Triphosphates, PEX, and PCR Construction of Base‐Modified DNA (2010) (6)
- Modular Synthesis of 4-Aryl-and 4-Amino-Substituted Benzene C-2'-Deoxyribonucleosides (2008) (6)
- C‐Nucleosides: Synthetic Strategies and Biological Applications (2010) (6)
- Vicinal Diol‐Tethered Nucleobases as Targets for DNA Redox Labeling with Osmate Complexes (2020) (5)
- Synthesis of Substituted Benzyl Homo‐C‐Ribonucleosides and ‐Nucleotides as Carba Analogues of Phosphoribosylanthranilate (2012) (5)
- Solid-phase recombinase polymerase amplification using ferrocene-labelled dNTPs for electrochemical detection of single nucleotide polymorphisms (2021) (5)
- Photocolouration of 2,4,4,6-Tetraaryl-1,4-dihydropyridines: A Semiempirical Quantum Chemical Study (1994) (5)
- Hydroxymethylations of Aryl Halides by Pd-Catalyzed Cross-Couplings with (Benzoyloxy)methylzinc Iodide - Scope and Limitations of the Reaction (2008) (5)
- 1,3‐Diketone‐Modified Nucleotides and DNA for Cross‐Linking with Arginine‐Containing Peptides and Proteins (2021) (5)
- SYNTHESIS OF (PURIN-6-YL)ACETATES AND THEIR TRANSFORMATIONS TO 6-(2-HYDROXYETHYL)- AND 6-(CARBAMOYLMETHYL)PURINES (2009) (4)
- Theoretical study of the stability of the DNA duplexes modified by a series of hydrophobic base analogues. (2009) (4)
- Cytostatic 6-Arylpurine Nucleosides. Part 3. Synthesis and Structure—Activity Relationship Study in Cytostatic Activity of 6-Aryl-, 6-Hetaryl-, and 6-Benzylpurine Ribonucleosides. (2001) (4)
- Polymerase Synthesis of Base-Modified DNA (2016) (4)
- Electrochemical Detection of Single-Nucleotide Polymorphism Associated with Rifampicin Resistance in Mycobacterium tuberculosis Using Solid-Phase Primer Elongation with Ferrocene-Linked Redox-Labeled Nucleotides (2021) (4)
- Cleavage of DNA containing 5-fluorocytosine or 5-fluorouracil by type II restriction endonucleases. (2015) (4)
- Synthesis, Photophysical Properties and Biological Profiling of Benzothieno-Fused 7-Deazapurine Ribonucleosides. (2020) (4)
- Dual redox labeling of DNA as a tool for electrochemical detection of p53 protein-DNA interactions. (2019) (4)
- Electrochemical reduction of azidophenyl-deoxynucleoside conjugates at mercury surface (2018) (3)
- Preparation and Spectroscopic Properties of Spirocyclic 1-Methyl-2,4,4,6-tetraaryl-1,4-dihydropyridines (1994) (3)
- Butylacrylate‐nucleobase Conjugates as Targets for Two‐step Redox Labeling of DNA with an Osmium Tetroxide Complex (2018) (3)
- A Facile Synthesis of 2-(Aminomethyl)purines (1994) (3)
- Covalent Analogues of Nucleobase-Pairs (2003) (3)
- Efficient One-Step Synthesis of Optically Pure (Adenin-8-yl)phenylalanine Nucleosides. (2006) (3)
- Synthesis and Biological Profiling of Pyrazolo-fused 7-Deazapurine Nucleosides. (2020) (3)
- Synthesis and Antitrypanosomal Activity of 6-Substituted 7-Methyl-7-deazapurine Nucleosides. (2021) (3)
- Dichotomy in Regioselective Cross-Coupling Reactions of 6,8-Dichloropurines with Phenylboronic Acid and Methylmagnesium Chloride: Synthesis of 6,8-Disubstituted Purines. (2004) (3)
- Nucleotides bearing aminophenyl- or aminonaphthyl-3-methoxychromone solvatochromic fluorophores for the enzymatic construction of DNA probes for the detection of protein-DNA binding. (2021) (3)
- Polymerase Synthesis of DNA Containing Iodinated Pyrimidine or 7‐Deazapurine Nucleobases and Their Post‐synthetic Modifications through the Suzuki‐Miyaura Cross‐Coupling Reactions (2021) (3)
- Aqueous-Phase Suzuki—Miyaura Cross-Coupling Reactions of Free Halopurine Bases. (2007) (3)
- ChemInform Abstract: The Suzuki-Miyaura Cross-Coupling Reactions of 2-, 6-, or 8-Halopurines with Boronic Acids Leading to 2-, 6-, or 8-Aryl- and -Alkenylpurine Derivatives. (2002) (2)
- A Facile Synthesis of 6‐Cyanopurine Bases. (1996) (2)
- Synthesis and Cytostatic Activity of Nucleosides and Acyclic Nucleoside Analogues Derived from 6-(Trifluoromethyl)purines. (2000) (2)
- Photocaged 5-(Hydroxymethyl)pyrimidine Nucleoside Phosphoramidites for Specific Photoactivatable Epigenetic Labeling of DNA. (2020) (2)
- Glucosylated 5-hydroxymethylpyrimidines as epigenetic DNA bases regulating transcription and restriction cleavage. (2022) (2)
- Cyclotrimerization of 6-Ethynylpurines. Synthesis of 1,2,4- and 1,3,5-Tris(purin-6-yl)benzenes as Novel Hoogsteen-Triplet Analogues. (2001) (2)
- Synthesis and Anti-trypanosomal Activity of 3'-Fluororibonucleosides Derived from 7-Deazapurine Nucleosides. (2021) (2)
- [2+2+2]-Cocyclotrimerization of 6-Alkynyl-7-benzylpurines with α,ω-Diynes (2010) (2)
- Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists (2022) (2)
- Synthesis and Antiviral Activity of Acyclic Nucleotide Analogues Derived from 6‐(Aminomethyl)purines and Purine‐6‐carboxamidines. (1997) (2)
- Synthesis of Acyclic Nucleotide Analogues Derived from 2-Amino-6-C-Substituted Purines via Cross-Coupling Reactions of 2-Amino-9-{2-[(diisopropoxyphosphoryl)methoxy]ethyl}-6-halopurines with Diverse Organometallic Reagents. (2001) (2)
- Synthesis of 2-Substituted 6-(Hydroxymethyl)purine Bases and Nucleosides. (2006) (2)
- Cross‐Coupling Reactions of Halopurines with Aryl‐ and Alkyltrifluoroborates. The Scope and Limitations in the Synthesis of Modified Purines. (2009) (2)
- Sugar-Modified Derivatives of Cytostatic 6-(Het)aryl-7-deazapurine Nucleosides: 2′-C-Methylribonucleosides, Arabinonucleosides and 2′-Deoxy-2′-fluoroarabinonucleosides. (2011) (2)
- Ferrocene-Containing DNA Monolayers: Influence of Electrostatics on the Electron Transfer Dynamics (2021) (2)
- Cytostatic and Antiviral 6-Arylpurine Ribonucleosides. Part 8. Synthesis and Evaluation of 6-Substituted Purine 3′-Deoxyribonucleosides. (2007) (1)
- C—H Trifluoromethylations of 1,3‐Dimethyluracil and Reactivity of the Products in C—H Arylations. (2014) (1)
- Direct C—H Arylation of Purines: Development of Methodology and Its Use in Regioselective Synthesis of 2,6,8-Trisubstituted Purines. (2007) (1)
- ChemInform Abstract: The Suzuki-Miyaura Cross-Coupling Reactions of 6-Halopurines with Boronic Acids Leading to 6-Aryl- and 6-Alkenylpurines. (1999) (1)
- Glyoxal-Linked Nucleotides and DNA for Bioconjugations and Cross-Linking with Arginine-Containing Peptides and Proteins. (2022) (1)
- Cross-coupling reactions of 2-amino-6-halopurine derivatives with organometallic reagents leading to 6-alkylated purine acyclic nucleotide analogues (1999) (1)
- Tvorba C-C a C-X vazeb cross-coupling reakcemi katalyzovanymi komplexy přechodnych kovů (2003) (1)
- Novel modified purine bases and nucleosides: new methodologies of synthesis and biological activity. (2005) (1)
- Efficient One-Step Synthesis of Optically Pure (Adenin-8-yl)phenylalanine Nucleosides (2005) (1)
- Traceless enzymatic synthesis of monodispersed hypermodified oligodeoxyribonucleotide polymers from RNA templates. (2022) (1)
- Faculty Opinions recommendation of Oxetane grafts site-selectively installed on native disulfides enhance protein stability and activity in vivo. (2017) (1)
- Cobalt-Induced Synthesis of 6-(Pyridin-2-yl)purines by Microwave-Enhanced [2 + 2 + 2] Cyclotrimerization. (2008) (1)
- MTB adenosine kinase in complex with gamma-Thio-ATP (2014) (1)
- Cocyclotrimerization of 6-alkynylpurines with diynes as a novel approach to biologically active 6-arylpurines (2005) (1)
- Homologues of epigenetic pyrimidines: 5-alkyl-, 5-hydroxyalkyl and 5-acyluracil and -cytosine nucleotides: synthesis, enzymatic incorporation into DNA and effect on transcription with bacterial RNA polymerase (2022) (1)
- Novel Modified Purine Bases and Nucleosides: New Methodologies of Synthesis and Biological Activity (2008) (1)
- Synthesis of Phenol and Pyridone C-Ribo- and 2′-Deoxyribonucleosidesby Palladium-Catalyzed Hydroxylations of Haloaryl C-Nucleosides (2010) (1)
- Modular synthesis of 5-substituted thiophen-2-yl C-2'-deoxyribonucleosides (2008) (1)
- Regioselective Cross-Coupling Reactions in the Synthesis of Multisubstituted Purine Bases and Nucleosides (2006) (1)
- Intramolecular Direct C—H Arylation Approach to Fused Purines. Synthesis of Purino[8,9-f]phenanthridines and 5,6-Dihydropurino[8,9-a]isoquinolines. (2010) (1)
- Direct C–H arylation of purines and purine nucleosides (2008) (1)
- Synthesis of 2,6-Substituted 7-(Het)aryl-7-deazapurine Nucleobases (2,4-Disubstituted 5-(Het)aryl-pyrrolo[2,3-d]pyrimidines) (2017) (1)
- Acyclic nucleotide analogues derived from 6-(1-aminoalkyl)purines (1996) (1)
- Novel base-functionalized DNA. Efficient methodology for construction and bioanalytical applications. (2008) (1)
- The first direct CH arylation of purine nucleosides (2008) (1)
- Synthesis of modified nucleosides and oligonucleotides bearing bipyridine or phenanthroline ligands (2005) (1)
- Palladium‐Catalyzed Cross‐Coupling Reactions in C6 Modifications of Purine Nucleosides (2007) (1)
- Epigenetic Pyrimidine Nucleotides in Competition with Natural dNTPs as Substrates for Diverse DNA Polymerases (2022) (1)
- Nucleotides Bearing Red Viscosity-Sensitive Dimethoxy-Bodipy Fluorophore for Enzymatic Incorporation and DNA Labeling. (2022) (1)
- Redox labeling and redox coding of nucleic acids (2014) (1)
- Thienopyrrolo[2, 3-d ]pyrimidines, New Tricyclic Nucleobase Analogues: Synthesis and Biological Activities (2018) (1)
- Regioselectivity in Cross‐Coupling Reactions of 2,6,8‐Trichloro‐9‐(tetrahydropyran‐2‐yl)purine: Synthesis of 2,6,8‐Trisubstituted Purine Bases. (2005) (1)
- Covalent Analogues of DNA Base‐Pairs and Triplets. Part 2. Synthesis and Cytostatic Activity of Bis(purin‐6‐yl)acetylenes, ‐diacetylenes and Related Compounds. (2002) (1)
- Synthesis of Cyclic and Acyclic Nucleoside Phosphonates and Sulfonamides Derived from 6-(Thiophen-2-yl)-7-fluoro-7-deazapurine (2019) (1)
- Synthesis of Acyclic Nucleotide Analogues Derived from 6- Hetarylpurines via Cross-Coupling Reactions of 9-(2-( Diethoxyphosphonylmethoxy)ethyl)-6-iodopurine with Hetaryl Organometallic Reagents. (1997) (1)
- Cocyclotrimerization of 6-alkynylpurines with alpha,omega-diynes as a novel approach to biologically active 6-arylpurines. (2004) (1)
- Modular and Practical Synthesis of 6‐Substituted Pyridin‐3‐yl C‐Nucleosides. (2008) (1)
- Redox labelling of nucleic acids for analyzing nucleotide sequences and monitoring DNA-protein interactions (2011) (1)
- Nucleobase Modification as Redox DNA Labeling for Electrochemical Detection (2012) (1)
- Correction to “Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides” (2019) (0)
- Lipid-linked nucleoside triphosphates for enzymatic synthesis of hydrophobic oligonucleotides with enhanced membrane anchoring efficiency (2023) (0)
- Synthesis of (Purin‐6‐yl)acetates and Their Transformations to 6‐(2‐Hydroxyethyl)‐ and 6‐(Carbamoylmethyl)purines. (2010) (0)
- The selection of a hydrophobic 7-phenylbutyl-7-deazaadenine-modified DNA aptamer with high binding affinity for the Heat Shock Protein 70 (2023) (0)
- Preparation and Spectroscopic Properties of Spirocyclic 1-Methyl-2,4,4, 6-tetraaryl-1,4-dihydropyridines. (1994) (0)
- New approaches to synthesis of C -deoxyribosides starting from C -alkynyldeoxyribosides (2008) (0)
- Cover Feature: Tuning of Oxidation Potential of Ferrocene for Ratiometric Redox Labeling and Coding of Nucleotides and DNA (Chem. Eur. J. 6/2020) (2020) (0)
- [2+2+2]-co-Cyclotrimerization of 6-alkynylpurines with diynes: A method for preparation 6-arylpurines (2002) (0)
- Purine bases and nucleosides bearing functionalized C-substituents in position 6. Synthesis and biological activities (2008) (0)
- Synthesis of acyclic nucleotide analogues derived from 6-(aminomethyl)purines and purine-6-carboxamidines (1996) (0)
- Synthesis of C-arylribosides by catalytic [2+2+2]-cyclotrimerization reaction (2005) (0)
- Synthesis of Polycyclic Hetero-Fused 7-Deazapurine Heterocycles and Nucleosides through C–H Dibenzothiophenation and Negishi Coupling (2022) (0)
- transformable redox label of DNA suitable for electrochemical detection of DNA – protein interactions † (2014) (0)
- Cocyclotrimerization of 6‐Alkynylpurines with α,ω‐Diynes as a Novel Approach to Biologically Active 6‐Arylpurines. (2005) (0)
- 2-SUBSTITUTED dATP DERIVATIVES AS BUILDING BLOCKS FOR ENZYMATIC SYNTHESIS OF DNA MODIFIED IN THE MINOR GROOVE (2019) (0)
- Aminophenyl- and nitrophenyl-labeled DNA. Synthesis by polymerase incorporation of nucleoside triphosphates and electrochemical properties (2008) (0)
- Faculty Opinions recommendation of A small-molecule fusion inhibitor of influenza virus is orally active in mice. (2019) (0)
- Micobacterial Adenosine Kinase in complex with inhibitor (2014) (0)
- Tail labelled oligonucleotide probes for the detection of DNA-protein interactions (2011) (0)
- Preparation of modified oligonucleotides by nicking enzyme amplification reaction (2014) (0)
- Synthesis of acyclic nucleotide analogues derived from 2-(aminomethyl)purine bases (1995) (0)
- Utilisation of enzymatic labelling with 4-aminophtalimide and 4-hydroxybenzylideneimidazolinone fluorescent derivates for monitoring of DNA-protein interaction (2014) (0)
- Faculty Opinions recommendation of A synthetic genetic polymer with an uncharged backbone chemistry based on alkyl phosphonate nucleic acids. (2019) (0)
- A Facile Synthesis of 2-(Aminomethyl)purines. (1995) (0)
- Synthesis of Purines Bearing Functionalized C-Substituents by the Conjugate Addition of Nucleophiles to 6-Vinylpurines and 6-Ethynylpurines. (2007) (0)
- Covalently linked purine dimers or trimers and purine–pyrimidine conjugates – analogues of nucleobase-pairs or triplets (2002) (0)
- Syntheses of Purines Bearing Carbon Substituents in Positions 2, 6 or 8 by Metal- or Organometal-Mediated C—C Bond-Forming Reactions (2003) (0)
- Synthesis of modified fluorescent nucleosides (2008) (0)
- Studium tautomerních rovnováh purinových derivátů pomocínízkoteplotní NMR spektroskopie a kvantově chemických výpočtů (2003) (0)
- Synthesis of (Purin‐6‐yl)acetates and 6‐(2‐Hydroxyethyl)purines via Cross‐Couplings of 6‐Chloropurines with the Reformatsky Reagent. (2007) (0)
- Synthesis of Protected (Purin-6-yl)glycines via Pd-Catalyzed α-Arylation of Ethyl N-(Diphenylmethylidene)glycinate with 6-Iodopurines. (2004) (0)
- Towards a novel approach to C-nucleosides (2005) (0)
- ChemInform Abstract: Regioselective Direct C-H Arylations of Protected Uracils. Synthesis of 5- and 6-Aryluracil Bases. (2011) (0)
- Cytostatic and Antiviral 6-Arylpurine Ribonucleosides. Part 9. Synthesis and Evaluation of 6-Substituted 3-Deazapurine Ribonucleosides. (2009) (0)
- Editorial: A Smooth Transition … (2013) (0)
- Faculty Opinions recommendation of Synthesis of proteins by automated flow chemistry. (2020) (0)
- Novel Method for Preparation of Highly Substituted 6‐Arylpurines by Reactions of 6‐Alkynylpurines with Zirconacyclopentadienes. (2005) (0)
- ChemInform Abstract: Cross-Coupling Reactions of Nucleoside Triphosphates Followed by Polymerase Incorporation. Construction and Applications of Base-Functionalized Nucleic Acids. (2008) (0)
- Faculty Opinions recommendation of Fluorescent Isoindole Crosslink (FlICk) Chemistry: A Rapid, User-friendly Stapling Reaction. (2019) (0)
- Purine derivatives: Substituent effects as monitored by NMR (2007) (0)
- Faculty Opinions recommendation of A synthetic molecular system capable of mirror-image genetic replication and transcription. (2016) (0)
- Synthesis of modified nucleosides and nucleoside triphosphates bearing oligopyridine ligands (2008) (0)
- Polymerase synthesis of base-modified DNA: new methods and new applications (2014) (0)
- Mechanisms by which Human DNA Primase Chooses to Polymerize a NTP † (2010) (0)
- Faculty of 1000 evaluation for RNA control by photoreversible acylation. (2018) (0)
- Hetaryl derivatives of 7-deazapurine ribonucleosides: potent cytostatic agents (2011) (0)
- Dichotomy in regioselectivity of Pd-catalyzed direct C–H arylation of protected uracils (2011) (0)
- Synthesis of (purin-6-yl)amino acids (2005) (0)
- Development of a general and modular approach to C -nucleosides (2011) (0)
- Cytostatic 6-Arylpurine Nucleosides. Part 2. Synthesis of Sugar-Modified Derivatives: 9-(2-Deoxy-β-D-erythro-pentofuranosyl)-, 9-(5-Deoxy-β-D-ribofuranosyl)- and 9-(2,3-Dihydroxypropyl)-6-phenylpurines. (2001) (0)
- Covalent Analogues of DNA Base‐Pairs and Triplets. Part 5. Synthesis of Purine‐Purine and Purine‐Pyrimidine Conjugates Connected by Diverse Types of Acyclic Carbon Linkages. (2003) (0)
- Faculty Opinions recommendation of Dinucleoside polyphosphates act as 5'-RNA caps in bacteria. (2020) (0)
- Chemoselective Synthesis of 4,5‐Diarylpyrrolo[2,3‐d]pyrimidines (6,7‐Diaryl‐7‐deazapurines) by Consecutive Suzuki and Liebeskind—Srogl Cross‐Couplings. (2015) (0)
- Synthesis of (purin-6-yl)acetates and their transformations (2008) (0)
- New oxidative labels for electrochemical detection of DNA (2014) (0)
- Synthesis of 6-phenylpurine bases and nucleosides by Suzuki–Miyaura cross-coupling reactions of 6-chloropurines with substituted phenylboronic acids (1999) (0)
- ChemInform Abstract: Synthesis of Benzamide-C-ribonucleosides by Pd-Catalyzed Aminocarbonylations. (2009) (0)
- Polymerase synthesis of modified DNA containing cytosine in major groove (2011) (0)
- Synthesis of biaryl-substituted fluorescent nucleosides and nucleoside triphosphates and their incorporation to DNA (2011) (0)
- Sonogashira Reactions of α- and β-1-Ethynyl-2-deoxyribosides: Synthesis of Acetylene-Extended C-Nucleosides. (2010) (0)
- Modular synthesis of 5-substituted thiophene and furan C -nucleosides and their analogues (2011) (0)
- trans-Cyclooctene- and Bicyclononyne-Linked Nucleotides for Click Modification of DNA with Fluorogenic Tetrazines and Live Cell Metabolic Labeling and Imaging (2023) (0)
- Competitive incorporations of modified versus natural nucleotides by DNA polymerases (2014) (0)
- SYNTHESIS OF NOVEL HETERO-FUSED 7-DEAZAPURINE RIBONUCLEOSIDES (2019) (0)
- New 7-deazapurinnukleotider for therapeutic uses (2010) (0)
- Ir‐Catalyzed C—H Silylations of Phenyldeazapurines. (2016) (0)
- Faculty Opinions recommendation of Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA. (2014) (0)
- Synthesis of Enantiomerically Pure (Purin‐6‐yl)phenylalanines and Their Nucleosides, a Novel Type of Purine‐Amino Acid Conjugates. (2005) (0)
- Progress in Acyclic Nucleoside and Nucleotide Chemistry and Application (1998) (0)
- Perfluoroalkylation of 6‐Iodopurines by Trimethyl(perfluoroalkyl)silanes. Synthesis of 6‐(Perfluoroalkyl)purine Bases, Nucleosides and Acyclic Nucleotide Analogues. (1999) (0)
- 6-Aryl- and 6-heteroarylpurines via cyclotrimerization. (2008) (0)
- Synthesis of 2,6-Disubstituted Pyridin-3-yl C-2′-Deoxyribonucleosides Through Chemoselective Transformations of Bromo-chloropyridine C-Nucleosides. (2013) (0)
- Tautomerism of Purine Derivatives Investigated byLow-Temperature NMR and Theoretical Calculations (2003) (0)
- Direct C—H Sulfenylation of Purines and Deazapurines. (2013) (0)
- Faculty Opinions recommendation of Synthesis and fluorescence characteristics of ATP-based FRET probes. (2013) (0)
- Inside Cover: Butylacrylate-nucleobase Conjugates as Targets for Two-step Redox Labeling of DNA with an Osmium Tetroxide Complex (Electroanalysis 2/2018) (2018) (0)
- Synthesis of nucleotides bearing oligopyridine ligands and their incorporation into DNA (2011) (0)
- A New Modular and Practical Methodology for the Synthesis of 4‐ or 3‐Substituted Phenyl C‐Nucleosides. (2006) (0)
- Synthesis of Base-Modified dNTPs Through Cross-Coupling Reactions and Their Polymerase Incorporation to DNA. (2019) (0)
- Vinyl-modified DNA and its cleavage by restriction endonucleases (2014) (0)
- Abstract 3657: 6-(Het)aryl-7-Deazapurine Ribonucleosides as Potent Novel Cytostatic Agents that Interfere with RNA Synthesis (2010) (0)
- Cytostatic 6-Arylpurine Nucleosides. Part 5. Synthesis of 8-Substituted 6-Phenylpurine Ribonucleosides. (2003) (0)
- Cover Feature: Nucleotide‐Bearing Benzylidene‐Tetrahydroxanthylium Near‐IR Fluorophore for Sensing DNA Replication, Secondary Structures and Interactions (Chem. Eur. J. 52/2020) (2020) (0)
- Celebrating Czech Chemistry. (2020) (0)
- Correction: Traceless enzymatic synthesis of monodispersed hypermodified oligodeoxyribonucleotide polymers from RNA templates. (2022) (0)
- Direct C—H Borylation and C—H Arylation of Pyrrolo[2,3-d]pyrimidines: Synthesis of 6,8-Disubstituted 7-Deazapurines. (2009) (0)
- Cross-Coupling Reactions of Halopurines with Aryl- and Alkyltrifluoro- borates; The Scope and Limitations in the Synthesis of Modified Purines Cross-Coupling Reactions of Halopurines with Aryl- and Alkyltrifluoroborates (2009) (0)
- Synthesis and biological activity of thiophene fused 7-deazapurine ribonucleosides (2014) (0)
- Covalent Analogues of DNA Base-Pairs and Triplets. Part 4. Synthesis of Trisubstituted Benzenes Bearing Purine and/or Pyrimidine Rings by Cyclotrimerization of 6-Ethynylpurines and/or 5-Ethynyl-1,3-dimethyluracil. (2003) (0)
- Study of DNA-protein interactions by cross-link formation using aqueous Michael addition (2014) (0)
- A General Regioselective Approach to 2,4-Disubstituted Pyrimidin-5-yl C-2-Deoxyribonucleosides. (2012) (0)
- Polymerase construction of base-modified DNA for chemical biology (2011) (0)
- A modular methodology for the synthesis of 3- and 4-substituted benzene and aniline C-ribonucleosides (2008) (0)
- Polymerase synthesis of new photocaged DNA (2014) (0)
- [2 + 2 + 2]-Cocyclotrimerization of 6-Alkynyl-7-benzylpurines with α,ω-Diynes. (2011) (0)
- Modular methodology for the syntheses of various aryl C-2'-deoxyribonucleosides (2008) (0)
- Synthesis of purines bearing functionalized C-substituents by nucleophilic additions to 6-ethynyl- or 6-vinylpurines (2005) (0)
- Nouveaux nucléosides 7-déazapurine à des fins thérapeutiques (2010) (0)
- Synthesis and transformations of 6-(hydroxymethyl)purines (2005) (0)
- Synthesis of 4-(het)aryl pyrimido[4,5-b]indole ribonucleosides (2011) (0)
- Synthesis of carba-analogues of myoseverin (2002) (0)
- Hydroxymethylations of Aryl Halides by Pd‐Catalyzed Cross‐Couplings with (Benzoyloxy)methylzinc Iodide — Scope and Limitations of the Reaction. (2008) (0)
- Faculty Opinions recommendation of A short de novo synthesis of nucleoside analogs. (2020) (0)
- Pyrido-Fused Deazapurine Bases: Synthesis and Glycosylation of 4-Substituted 9H-Pyrido[2′,3′:4,5]- and Pyrido[4′,3′:4,5]pyrrolo[2,3-d]pyrimidines (2020) (0)
- Covalent Analogues of DNA Base‐Pairs and Triplets. Part 7. Synthesis and Cytostatic Activity of Bis(purin‐6‐yl)acetylene and ‐diacetylene Nucleosides. (2005) (0)
- Cover Feature: Synthesis of Dihydroxyalkynyl and Dihydroxyalkyl Nucleotides as Building Blocks or Precursors for Introduction of Diol or Aldehyde Groups to DNA for Bioconjugations (Chem. Eur. J. 46/2018) (2018) (0)
- Switching the Regioselectivity of Direct C—H Arylation of 1,3-Dimethyluracil. (2009) (0)
- C-C and C-X Bond Formation by Cross-coupling Reactions Catalyzed by Transition Metal Complexes (2003) (0)
- Synthesis of Acyclic Nucleotide Analogues Derived from N-Substituted 6- (1-Aminoethyl)purines via 6-Acetylpurine Derivatives. (1997) (0)
- Faculty Opinions recommendation of New codons for efficient production of unnatural proteins in a semisynthetic organism. (2020) (0)
- Synthesis of modified nucleosides, nucleotides and oligonucleotides bearing metal complexes (2008) (0)
- Synthesis of Acyclic Nucleotide Analogues Derived from 2-(Aminomethyl) adenine and 2-(Aminomethyl)hypoxanthine. (1995) (0)
- Direct enzymatic synthesis of aldehyde-functionalized DNA and its conjugation with hydrazines and amines (2011) (0)
- Abstract 5100: AB61, a new potent nucleoside cytostatic: Molecular mechanisms of action and preclinical activity (2017) (0)
- Studium struktury a NMR parametrů N-substituovaných derivátůpurinu (2003) (0)
- Synthesis of (Purin-6-yl)methylphosphonate Bases and Nucleosides. (2010) (0)
- Front Cover: Institute Feature: IOCB Prague (Eur. J. Org. Chem. 37/2018) (2018) (0)
- Electrochemical analysis of DNA using switchable redox moieties (2014) (0)
- Synthesis of 6,8,9-Tri- and 2,6,8,9-Tetrasubstituted Purines by a Combination of the Suzuki Cross-Coupling, N-Arylation, and Direct C—H Arylation Reactions. (2009) (0)
- Synthesis of nucleosides and nucleoside triphosphates bearing anthraquinone substituents as redox probes and their enzymatic incorporation to DNA (2011) (0)
- SYNTHESIS AND EVALUATION OF 6-SUBSTITUTED 3-DEAZAPURINE (2008) (0)
- Synthesis and BiologicalProfiling of Pyrazolo-Fused7‑Deazapurine Nucleosides (2020) (0)
- Synthesis of 6-Amino-, 6-Methyl- and 6-Aryl-2-(hydroxymethyl)purine Bases and Nucleosides. (2006) (0)
- [2 + 2 + 2]-Co-cyclotrimerization 6-Alkynylpurines with Diynes: A Method for Preparation of 6-Arylpurines. (2003) (0)
- Chloroacetamide-Modified Nucleotide and RNA for Bioconjugations and Cross-Linking with RNA-Binding Proteins. (2022) (0)
- Cover Feature: Institute Feature: IOCB Prague (Eur. J. Org. Chem. 37/2018) (2018) (0)
- Co‐ and Homocyclotrimerization Reactions of Protected 1‐Alkynyl‐2‐deoxyribofuranose. Synthesis of C‐Nucleosides, C‐Di‐ and C‐Trisaccharide Analogues. (2008) (0)
- Cytostatic 6-Arylpurine Nucleosides. Part 4. Synthesis of 2-Substituted 6-Phenylpurine Ribonucleosides. (2002) (0)
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