Michel Chrétien

Q: What Schools Are Affiliated With Michel Chrétien

Michel Chrétien is affiliated with the following schools: University of California, San Francisco, Harvard University, University of Western Ontario, Humboldt University of Berlin, University of California, Berkeley, McGill University, Université de Montréal, University of Oxford, University of Ottawa, Royal Postgraduate Medical School, University of Manitoba

Michel Chrétien's AcademicInfluence.com Rankings

Michel Chrétien

Law

#1775

World Rank

#2216

Historical Rank

Common Law

#54

World Rank

#61

Historical Rank

International Law

#272

World Rank

#362

Historical Rank

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Michel Chrétien's Degrees

Doctorate Medicine Université de Montréal
PhD Biochemistry Université de Montréal

Why Is Michel Chrétien Influential?

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According to Wikipedia, Michel Chrétien is a Canadian medical researcher specializing in neuroendocrinology research at the Institut de recherches cliniques de Montréal, or Clinical Research Institute of Montreal, . He is a younger brother of former Canadian prime minister, Jean Chrétien.

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Michel Chrétien's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): Liver regeneration and neuronal differentiation (2003) (1062)
Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides 1 Published on the World Wide Web on 17 August 1999. 1 (1999) (786)
PC1 and PC2 are proprotein convertases capable of cleaving proopiomelanocortin at distinct pairs of basic residues. (1991) (567)
NARC-1/PCSK9 and Its Natural Mutants (2004) (461)
PCSK9: A Key Modulator of Cardiovascular Health (2014) (452)
cDNA sequence of two distinct pituitary proteins homologous to Kex2 and furin gene products: tissue-specific mRNAs encoding candidates for pro-hormone processing proteinases. (1990) (425)
Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2. (1991) (421)
The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions. (1994) (378)
Cellular processing of the neurotrophin precursors of NT3 and BDNF by the mammalian proprotein convertases (1996) (358)
Mammalian subtilisin/kexin isozyme SKI-1: A widely expressed proprotein convertase with a unique cleavage specificity and cellular localization. (1999) (292)
Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases. (1996) (292)
Amino acids of the Torpedo marmorata acetylcholine receptor alpha subunit labeled by a photoaffinity ligand for the acetylcholine binding site. (1988) (282)
Eukaryotic protein processing: endoproteolysis of precursor proteins. (1997) (282)
Post-translational Processing of β-Secretase (β-Amyloid-converting Enzyme) and Its Ectodomain Shedding (2001) (260)
Distribution and regulation of the prohormone convertases PC1 and PC2 in the rat pituitary. (1992) (244)
cDNA structure, tissue distribution, and chromosomal localization of rat PC7, a novel mammalian proprotein convertase closest to yeast kexin-like proteinases. (1996) (241)
Isolation and Amino-acid Sequence of β-LPH from Sheep Pituitary Glands (1965) (237)
The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis. (2003) (224)
Proprotein convertases: lessons from knockouts (2006) (223)
Gene expression of prohormone and proprotein convertases in the rat CNS: a comparative in situ hybridization analysis (1993) (220)
cDNA structure of the mouse and rat subtilisin/kexin-like PC5: a candidate proprotein convertase expressed in endocrine and nonendocrine cells. (1993) (215)
Proprotein convertases in tumor progression and malignancy: novel targets in cancer therapy. (2002) (208)
Plasma PCSK9 levels are significantly modified by statins and fibrates in humans (2008) (207)
Immunohistochemical Localization of β-Lipotropic Hormone in the Pituitary Gland (1977) (206)
Post-translational processing of b -secretase (BACE) and its ectodomain shedding: the pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid A b production (2000) (199)
Selective inhibition of heme oxygenase, without inhibition of nitric oxide synthase or soluble guanylyl cyclase, by metalloporphyrins at low concentrations. (1999) (192)
Precursor Convertases: An Evolutionary Ancient, Cell‐Specific, Combinatorial Mechanism Yielding Diverse Bioactive Peptides and Proteins (1998) (188)
Amino acid sequence of homologous rat atrial peptides: natriuretic activity of native and synthetic forms. (1984) (186)
Amino acid sequence of rabbit kidney neutral endopeptidase 24.11 (enkephalinase) deduced from a complementary DNA. (1987) (184)
PCSK9‐deficient mice exhibit impaired glucose tolerance and pancreatic islet abnormalities (2010) (183)
Neuroendocrine secretory protein 7B2: structure, expression and functions. (2001) (182)
An infant with deletion of the distal long arm of chromosome 15 (q26.1----qter) and loss of insulin-like growth factor 1 receptor gene. (1991) (181)
Impaired fertility in mice deficient for the testicular germ-cell protease PC4. (1997) (180)
Inhibition of Proprotein Convertases Is Associated with Loss of Growth and Tumorigenicity of HT-29 Human Colon Carcinoma Cells (2001) (179)
Testicular expression of PC4 in the rat: molecular diversity of a novel germ cell-specific Kex2/subtilisin-like proprotein convertase. (1992) (176)
Comparative biosynthesis, covalent post-translational modifications and efficiency of prosegment cleavage of the prohormone convertases PC1 and PC2: glycosylation, sulphation and identification of the intracellular site of prosegment cleavage of PC1 and PC2. (1993) (172)
Action of testosterone on the differentiation and secretory activity of a target organ: the submaxillary gland of the mouse. (1977) (170)
Proprotein and prohormone convertases of the subtilisin family Recent developments and future perspectives (1992) (161)
The Multifaceted Proprotein Convertases: Their Unique, Redundant, Complementary, and Opposite Functions* (2013) (156)
Erratum: Isolation, purification, and characterization of γ-lipotropic hormone from sheep pituitary glands (1967) (156)
Identification of a biologically active circulating form of rat atrial natriuretic factor. (1985) (152)
The Subtilisin/Kexin Family of Precursor Convertases: Emphasis on PC1, PC2/7B2, POMC and the Novel Enzyme SKI‐1 (1999) (140)
Pro‐protein convertase gene expression in human breast cancer (1997) (140)
Biosynthesis of beta-endorphin from beta-lipotropin and a larger molecular weight precursor in rat pars intermedia. (1978) (140)
Crimean-Congo Hemorrhagic Fever Virus Glycoprotein Proteolytic Processing by Subtilase SKI-1 (2003) (135)
The Prosegments of Furin and PC7 as Potent Inhibitors of Proprotein Convertases (1999) (130)
Ontogeny of the prohormone convertases PC1 and PC2 in the mouse hypophysis and their colocalization with corticotropin and alpha-melanotropin. (1993) (130)
The propeptide Asn1-Tyr126 is the storage form of rat atrial natriuretic factor. (1987) (128)
Inhibition of Chikungunya Virus Infection in Cultured Human Muscle Cells by Furin Inhibitors (2008) (127)
Proteases and posttranslational processing of prohormones: a review. (1983) (127)
Isolation of peptides with opiate activity from sheep and human pituitaries: relationship to beta-lipotropin. (1976) (127)
Proprotein conversion is determined by a multiplicity of factors including convertase processing, substrate specificity, and intracellular environment. Cell type-specific processing of human prorenin by the convertase PC1. (1992) (126)
Isolation and NH2‐terminal sequence of a novel porcine anterior pituitary polypeptide (1982) (126)
Isolation and NH2-terminal sequence of a highly conserved human and porcine pituitary protein belonging to a new superfamily. Immunocytochemical localization in pars distalis and pars nervosa of the pituitary and in the supraoptic nucleus of the hypothalamus. (1983) (123)
CNS connections with the median raphe nucleus: Retrograde tracing with WGA‐apoHRP‐gold complex in the rat (1989) (123)
From β-lipotropin to β-endorphin and 'pro-opio-melanocortin' (1979) (122)
Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding. The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production. (2001) (118)
NH2-terminal fragment of rat pro-atrial natriuretic factor in the circulation: Identification, radioimmunoassay and half-life (1988) (113)
Furin-Like Proprotein Convertases Are Central Regulators of the Membrane Type Matrix Metalloproteinase–Pro-Matrix Metalloproteinase-2 Proteolytic Cascade in Atherosclerosis (2005) (108)
Novel loss-of-function PCSK9 variant is associated with low plasma LDL cholesterol in a French-Canadian family and with impaired processing and secretion in cell culture. (2011) (108)
Primary structure of a high M r form of rat atrial natriuretic factor (1984) (107)
Complete amino acid sequence of human seminal plasma β‐inhibin (1984) (106)
Molecular cloning and characterization of DNA sequences encoding rat and human atrial natriuretic factors. (1984) (106)
Inhibition of proprotein convertases-1, -7 and furin by diterpines of Andrographis paniculata and their succinoyl esters. (1999) (105)
Endoproteolytic processing of integrin pro-alpha subunits involves the redundant function of furin and proprotein convertase (PC) 5A, but not paired basic amino acid converting enzyme (PACE) 4, PC5B or PC7. (2000) (104)
Regulation of matrix metalloproteinase MT1-MMP/MMP-2 in cardiac fibroblasts by TGF-beta1 involves furin-convertase. (2004) (104)
Tissue distribution and molecular forms of a novel pituitary protein in the rat. (1984) (104)
The mouse homeoprotein mLIM-3 is expressed early in cells derived from the neuroepithelium and persists in adult pituitary. (1994) (100)
Complete amino acid sequence of BSP-A3 from bovine seminal plasma. Homology to PDC-109 and to the collagen-binding domain of fibronectin. (1987) (100)
Cellular Localization of the Prohormone Convertases in the Hypothalamic Paraventricular and Supraoptic Nuclei: Selective Regulation of PC1 in Corticotrophin-Releasing Hormone Parvocellular Neurons Mediated by Glucocorticoids (1997) (97)
Involvement of matrix metalloproteinases in the adipose conversion of 3T3-L1 preadipocytes. (2002) (94)
A specific homologous radioimmunoassay for human beta-endorphin: direct measurement in biological fluids. (1980) (94)
Chromogranin B (secretogranin I), a putative precursor of two novel pituitary peptides through processing at paired basic residues (1987) (93)
Developmental expression of the prohormone convertases PC1 and PC2 in mouse pancreatic islets. (1994) (91)
Plasma PCSK9 levels correlate with cholesterol in men but not in women. (2007) (89)
The proteolytic processing of pro-platelet-derived growth factor-A at RRKR(86) by members of the proprotein convertase family is functionally correlated to platelet-derived growth factor-A-induced functions and tumorigenicity. (2003) (89)
cDNA sequence of two distinct pituitary proteins homologous to Kex2 and furin gene products: tissue-specific mRNAs encoding candidates for pro-hormone processing proteinases. (1990) (89)
Mammalian neural and endocrine pro-protein and pro-hormone convertases belonging to the subtilisin family of serine proteinases. (1991) (88)
Pro-protein convertases of subtilisin/kexin family. (1994) (88)
Comparative cellular processing of the human immunodeficiency virus (HIV-1) envelope glycoprotein gp160 by the mammalian subtilisin/kexin-like convertases. (1996) (88)
7B2 Is a Specific Intracellular Binding Protein of the Prohormone Convertase PC2 (1995) (87)
The neuroendocrine precursor 7B2 is a sulfated protein proteolytically processed by a ubiquitous furin-like convertase. (1994) (86)
Biosynthesis and Enzymatic Characterization of Human SKI-1/S1P and the Processing of Its Inhibitory Prosegment* (2000) (86)
Human pituitary tryptase: molecular forms, NH2-terminal sequence, immunocytochemical localization, and specificity with prohormone and fluorogenic substrates. (1987) (86)
α1-Antitrypsin Portland Inhibits Processing of Precursors Mediated by Proprotein Convertases Primarily within the Constitutive Secretory Pathway* (1997) (86)
Deletion of the Gene Encoding Proprotein Convertase 5/6 Causes Early Embryonic Lethality in the Mouse (2006) (86)
Complete structure of the porcine pro-opiomelanocortin mRNA derived from the nucleotide sequence of cloned cDNA. (1983) (84)
In Vitro Characterization of the Novel Proprotein Convertase PC7* (1997) (84)
Structure-activity relationships of atrial natriuretic factor (ANF). I. Natriuretic activity and relaxation of intestinal smooth muscle. (1984) (83)
Enzymic characterization of murine and human prohormone convertase-1 (mPC1 and hPC1) expressed in mammalian GH4C1 cells. (1993) (82)
Mammalian Paired Basic Amino Acid Convertases of Prohormones and Proproteins a (1993) (81)
Chromogranin A can act as a reversible processing enzyme inhibitor (1987) (80)
Purification of three rat atrial natriuretic factors and their amino acid composition (1983) (80)
Electron microscopic immunocytochemical evidence for the involvement of the convertases PC1 and PC2 in the processing of proinsulin in pancreatic beta-cells. (1995) (78)
Distinct mRNA expression of the highly homologous convertases PC5 and PACE4 in the rat brain and pituitary (1995) (78)
Characterization of structural determinants and molecular mechanisms involved in pro-stromelysin-3 activation by 4-aminophenylmercuric acetate and furin-type convertases. (1996) (78)
Processing of prodynorphin by the prohormone convertase PC1 results in high molecular weight intermediate forms (1994) (77)
Implication of the proprotein convertases furin, PC5 and PC7 in the cleavage of surface glycoproteins of Hong Kong, Ebola and respiratory syncytial viruses: a comparative analysis with fluorogenic peptides. (2001) (74)
Primary structure of the major human pituitary pro-opiomelanocortin NH2-terminal glycopeptide. Evidence for an aldosterone-stimulating activity. (1981) (73)
Apolipoprotein A-I binds to a family of bovine seminal plasma proteins. (1989) (73)
Gene structure and chromosomal localization of plasma kallikrein. (1991) (73)
PCSK9 is phosphorylated by a Golgi casein kinase‐like kinase ex vivo and circulates as a phosphoprotein in humans (2008) (72)
Bovine adrenal chromaffin granules are a site of synthesis of atrial natriuretic factor. (1987) (71)
Implication of proprotein convertases in the processing and spread of severe acute respiratory syndrome coronavirus (2004) (71)
Concomitant synthesis of beta-endorphin and alpha-melanotropin from two forms of pro-opiomelanocortin in the rat pars intermedia. (1979) (70)
Isolation, structure, and synthesis of a human seminal plasma peptide with inhibin-like activity. (1984) (70)
Reduced cerebrospinal fluid levels of immunoreactive pro-opiomelanocortin related peptides (including beta-endorphin) in anorexia nervosa. (1987) (70)
Complete amino acid sequence of Shigella toxin B-chain. A novel polypeptide containing 69 amino acids and one disulfide bridge. (1986) (69)
Isolation from human seminal plasma of an abundant 16-kDa protein originating from the prostate, its identification with a 94-residue peptide originally described as beta-inhibin. (1987) (69)
The family of pro-hormone and pro-protein convertases. (1993) (67)
Structure-activity relationships of atrial natriuretic factor (ANF). II. Effect of chain-length modifications on vascular reactivity. (1985) (64)
STUDIES ON THE RENIN-ANGIOTENSIN SYSTEM IN HYPERTENSIVE PATIENTS. (1964) (63)
Prophylactic Efficacy of Quercetin 3-β-O-d-Glucoside against Ebola Virus Infection (2016) (62)
Immunocytochemical localization of a novel pituitary protein (7B2) within the rat brain and hypophysis. (1985) (62)
Primary structure determination of Escherichia coli heat-stable enterotoxin of porcine origin. (1983) (61)
Loss- and Gain-of-function PCSK9 Variants (2012) (61)
A rapid high-performance liquid chromatography purification method of lodinated polypeptide hormones (1980) (61)
Corticotropin releasing factor (CRF): effects on the release of pro-opiomelanocortin (POMC)-related peptides by human anterior pituitary cells in vitro. (1982) (60)
Quercetin-3-glucoside increases low-density lipoprotein receptor (LDLR) expression, attenuates proprotein convertase subtilisin/kexin 9 (PCSK9) secretion, and stimulates LDL uptake by Huh7 human hepatocytes in culture (2014) (58)
Complete amino acid sequence of a human pituitary glycopeptide: an important maturation product of pro-opiomelanocortin. (1981) (57)
Content of beta-LPH and its fragments (including endorphins) in anterior and intermediate lobes of the bovine pituitary gland. (1978) (57)
Nerve growth factor and proprotein convertases furin and PC7 in transected sciatic nerves and in nerve segments cultured in conditioned media: Their presence in Schwann cells, macrophages, and smooth muscle cells (1999) (56)
Antiviral activity of quercetin-3-β-O-D-glucoside against Zika virus infection (2017) (56)
Region specific expression of furin mRNA in the rat brain (1993) (56)
Inhibitory Specificity and Potency of proSAAS-derived Peptides toward Proprotein Convertase 1* (2001) (56)
Diversity of Novel Proteins in Gonadal Fluids (1988) (55)
Structure-Function Analysis of the Prosegment of the Proprotein Convertase PC5A* (2003) (55)
Differential effects of PCSK9 loss of function variants on serum lipid and PCSK9 levels in Caucasian and African Canadian populations (2013) (54)
The missing fragment of the pro-sequence of human pro-opiomelanocortin: sequence and evidence for C-terminal amidation. (1981) (52)
Atrial pronatriodilatin: a precursor for natriuretic factor and cardiodilatin (1984) (52)
The integrity of the RRGDL sequence of the proprotein convertase PC1 is critical for its zymogen and C-terminal processing and for its cellular trafficking. (1997) (51)
Adrenocortical Hormones in Human Hypertension and Their Relation to Angiotensin (1961) (50)
cDNA sequence of neuroendocrine protein 7B2 expressed in beta cell tumors of transgenic mice. (2009) (49)
Effects of Angiotensin Infusions on Aldosterone and Electrolyte Excretion in Normal Subjects and Patients with Hypertension and Adrenocortical Disorders* (1962) (49)
In vitro biosynthesis and chemical characterization of beta-lipotropin, gamma-lipotropin, and beta-endorphin in rat pars intermedia. (1978) (49)
Physiological variables measured under field conditions according to age and state of training in French Trotters. (2010) (48)
Effect of N-terminal portion of pro-opiomelanocortin on aldosterone release by human adrenal adenoma in vitro. (1981) (48)
Measurement of N-terminal (1-76) of human proopiomelanocortin in human plasma: correlation with adrenocorticotropin. (1983) (48)
The complete sequence of a novel human pituitary glycopeptide homologous to pig posterior pituitary glycopeptide. (1981) (48)
Sequence homologies between tonin, nerve growth factor γ-subunit, epidermal growth factor-binding protein and serine proteases (1981) (48)
Enzymic characterization in vitro of recombinant proprotein convertase PC4. (1999) (47)
Chronic ethanol treatment alters the biosynthesis of beta-endorphin by the rat neurointermediate lobe. (1983) (46)
Structure of the carboxyl propeptide of chicken type II procollagen determined by DNA and protein sequence analysis (1984) (46)
Chromosomal assignments of the genes for neuroendocrine convertase PC1 (NEC1) to human 5q15-21, neuroendocrine convertase PC2 (NEC2) to human 20p11.1-11.2, and furin (mouse 7[D1-E2] region). (1991) (45)
Isolation, purification, and characterization of gamma-lipotropic hormone from sheep pituitary glands. (1967) (45)
The amino acid sequences of frog heart atrial natriuretic‐like peptide and mammalian ANF are closely related (1988) (45)
β-endorphin induced akinesia in rats: Effect of apomorphine and α-methyl-p-tyrosine and related modifications of dopamine turnover in the basal ganglia (1977) (45)
Gene organization of the mouse pro-hormone and pro-protein convertase PC1. (1994) (44)
The cDNA sequence of the human pro-hormone and pro-protein convertase PC1. (1992) (44)
The testicular germ-cell protease PC4 is also expressed in macrophage-like cells of the ovary. (2001) (44)
Identification of the Released form of Atrial Natriuretic Factor by the Perfused Rat Heart (1986) (44)
Structure-activity relationships of atrial natriuretic factor (ANF). III. Correlation of receptor affinity with relative potency on aldosterone production in zona glomerulosa cells. (1985) (43)
Studies of the pathogenesis of human hypertension. The adrenal cortex and renal pressor mechanism. (1961) (43)
Biosynthesis of beta-endorphin by the neurointermediate lobes from rats treated with morphine or alcohol. (1981) (42)
Structure of the gene for the testis-specific proprotein convertase 4 and of its alternate messenger RNA isoforms. (1994) (41)
Lipotropin: localization by radioimmunoassay of endorphin precursors in pituitary and brain. (1977) (41)
A novel serine protease (IRCM-serine protease 1) from porcine neurointermediate and anterior pituitary lobes. Isolation, polypeptide chain structure, inhibitor sensitivity, and substrate specificity with fluorogenic peptide substrates. (1986) (40)
Expression of PCSK1 (PC1/3), PCSK2 (PC2) and PCSK3 (furin) in mouse small intestine (2009) (40)
β‐Amyloid protein converting enzyme 1 and brain‐specific type II membrane protein BRI3: binding partners processed by furin (2005) (40)
Biosynthesis and characterization of adrenocorticotropic hormone, alpha-melanocyte-stimulating hormone, and an NH2-terminal fragment of the adrenocorticotropic hormone/beta-lipotropin precursor from rat pars intermedia. (1979) (40)
60 YEARS OF POMC: From the prohormone theory to pro-opiomelanocortin and to proprotein convertases (PCSK1 to PCSK9). (2016) (39)
Selective cleavage of human ACTH, beta-lipotropin, and the N-terminal glycopeptide at pairs of basic residues by IRCM-serine protease 1. Subcellular localization in small and large vesicles. (1986) (39)
The major 40‐kDa glycoprotein in human prostatic fluid is identical to Zn‐α2‐glycoprotein (1987) (39)
Implication of the proprotein convertases furin, PC5 and PC7 in the cleavage of surface glycoproteins of Hong Kong, Ebola and respiratory syncytial viruses: a comparative analysis with fluorogenic peptides (2001) (38)
β-Endorphin concentrations in serum, hypothalamus and central gray of hypophysectomized and mediobasal hypothalamus lesioned rats (1982) (38)
Regulation of prohepcidin processing and activity by the subtilisin-like proprotein convertases Furin, PC5, PACE4 and PC7 (2008) (38)
Evidence for a novel pituitary protein (7B2) in human brain, cerebrospinal fluid and plasma: Brain concentrations in controls and patients with Alzheimer's disease (1987) (38)
The RGD Motif and the C-terminal Segment of Proprotein Convertase 1 Are Critical for Its Cellular Trafficking but Not for Its Intracellular Binding to Integrin α5β1 * (1999) (37)
In vitro elucidation of substrate specificity and bioassay of proprotein convertase 4 using intramolecularly quenched fluorogenic peptides. (2004) (37)
The distinct gene expression of the pro-hormone convertases in the rat heart suggests potential substrates (1995) (37)
Isolation and purification of Escherichia coli heat-stable enterotoxin of porcine origin. (1982) (37)
Partial amino acid sequence of a human seminal plasma peptide with inhibin‐like activity (1984) (36)
Regional distribution of a novel pituitary protein (7B2) in the rat brain (1985) (36)
Lipotropin, Melanotropin and Endorphin: In Vivo Catabolism and Entry into Cerebrospinal Fluid (1978) (36)
The major androgen‐dependent protease in dog prostate belongs to the kallikrein family: confirmation by partial amino acid sequencing (1984) (36)
Homologous IRCM-Serine Protease 1 from pituitary, heart atrium and ventricle: A common pro-hormone maturation enzyme? (1986) (36)
A targeted deletion/insertion in the mouse Pcsk1 locus is associated with homozygous embryo preimplantation lethality, mutant allele preferential transmission and heterozygous female susceptibility to dietary fat. (2007) (36)
The cDNA structure of the porcine pro‐hormone convertase PC2 and the comparative processing by PC1 and PC2 of the N‐terminal glycopeptide segment of porcine POMC (1992) (36)
Biosynthesis of beta-endorphin, beta-lipotropin and the putative ACTH-LPH precursor in the frog pars intermedia. (1978) (35)
pH‐induced conformational transitions of a molten–globule–like state of the inhibitory prodomain of furin: Implications for zymogen activation (2001) (35)
PRESENCE OF A PRE‐SEQUENCE (SIGNAL SEQUENCE) IN THE COMMON PRECURSOR TO ACTH AND ENDORPHIN AND THE ROLE OF GLYCOSYLATION IN PROCESSING OF THE PRECURSOR AND SECRETION OF ACTH AND ENDORPHIN * (1980) (35)
Selective Expression of the Proprotein Convertases Furin, PC5, and PC7 in Proliferating Vascular Smooth Muscle Cells of the Rat Aorta In Vitro (2001) (34)
The carboxy terminus of the precursor to vasopressin and neurophysin: immunocytochemistry in rat brain. (1982) (34)
Endoproteolytic Activation of &agr;v Integrin by Proprotein Convertase PC5 Is Required for Vascular Smooth Muscle Cell Adhesion to Vitronectin and Integrin-Dependent Signaling (2004) (34)
GAWK, a novel human pituitary polypeptide: isolation, immunocytochemical localization and complete amino acid sequence. (1985) (34)
Mechanotransduction by endothelial cells is locally generated, direction‐dependent, and ligand‐specific (2010) (34)
Kainic acid increases the expression of the prohormone convertases furin and PC1 in the mouse hippocampus (1996) (34)
A rapid fluorometric assay for the proteolytic activity of SKI‐1/S1P based on the surface glycoprotein of the hemorrhagic fever Lassa virus (2002) (34)
A novel human pituitary peptide containing the γ-MSH sequence (1980) (34)
Abnormal expression and processing of the proprotein convertases PC1 and PC2 in human colorectal liver metastases (2005) (34)
Proprotein convertases and the pathophysiology of human diseases: prospective considerations. (1995) (33)
Proprotein Convertase PC5 Regulation by PDGF-BB Involves PI3-Kinase/p70s6-Kinase Activation in Vascular Smooth Muscle Cells (2002) (33)
Molecular characterization, enzymatic analysis, and purification of murine proprotein convertase-1/3 (PC1/PC3) secreted from recombinant baculovirus-infected insect cells. (1998) (33)
In vitro biosynthesis of beta-endorphin, gamma-lipoprotein, and beta-lipotropin by the pars intermedia of beef pituitary glands. (1977) (32)
Aldosterone secretion inhibitory factor: a novel neuropeptide in bovine chromaffin cells. (1989) (32)
Amino acid sequence of rat submaxillary tonin reveals similarities to serine proteases (1984) (32)
Effect of chronic morphine treatment on beta-endorphin biosynthesis by the rat neurointermediate lobe. (1981) (32)
Molecular Biology of Brain and Endocrine Peptidergic Systems (2013) (32)
Evidence for proprotein convertase activity in the endoplasmic reticulum/early Golgi (2005) (32)
Neuropeptides in human cerebrospinal fluid. (1985) (31)
Purification and characterization of the N-terminal fragment of pro-opiomelanocortin from human pituitaries: homology to the bovine sequence. (1980) (31)
Reversed-phase high-performance liquid chromatographic purification and characterization of the adrenocorticotropin/lipotropin precursor and its fragments. (1980) (31)
Application of the multiple antigenic peptides (MAP) strategy to the production of prophormone convertases antibodies: Synthesis, characterization and use of 8‐branched immunogenic peptides (1995) (31)
The use of biomarkers in the prediction of survival in patients with pulmonary carcinoma (1990) (31)
Residues unique to the pro‐hormone convertase PC2 modulate its autoactivation, binding to 7B2 and enzymatic activity (1998) (31)
Proprotein convertases regulate insulin-like growth factor 1-induced membrane-type 1 matrix metalloproteinase in VSMCs via endoproteolytic activation of the insulin-like growth factor-1 receptor. (2004) (30)
Isolation and characterization of beta-lipolytic hormone from porcine pituitary gland. (1970) (30)
Chemistry and biosynthesis of pro-opiomelanocortin (1981) (30)
Malignant hypertension with hypokalemia in a patient with renin-producing pulmonary carcinoma. (1975) (30)
Regional heterogeneity in the processing of pro-opiomelanocortin in rat brain. (1983) (30)
Ostrich MSEL-neurophysin belongs to the class of two-domain "big" neurophysin as indicated by complete amino acid sequence of the neurophysin/copeptin. (2009) (29)
Rapid evolution of prostatic protein PSP94 suggested by sequence divergence between rhesus monkey and human cDNAs. (1991) (29)
Specific release of a novel pituitary polypeptide, 7B2, from rat anterior pituitary cells in vitro by luteinizing hormone-releasing hormone. (1986) (29)
In vitro biosynthesis of beta-endorphin in pituitary glands. (1977) (29)
Potentiation of carbon monoxide-induced relaxation of rat aorta by YC-1 [3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole]. (2000) (29)
The Effect of PCSK9 Loss‐of‐Function Variants on the Postprandial Lipid and ApoB‐Lipoprotein Response (2017) (29)
Proprotein Convertases Subtilisin/Kexin Type 9, an enzyme turned escort protein: Hepatic and extra hepatic functions (第9型前蛋白转换酶—枯草溶菌素/蛋白酶K，一种酶转变的护送蛋白：在肝脏与肝外的功能) (2013) (29)
Presence of vasopressin, oxytocin and neurophysin in the retina of mammals, effect of light and darkness, comparison with the neuropeptide content of the neurohypophysis and the pineal gland (1983) (28)
Partial N-terminal amino acid sequence of pro-opio-melanocortin (ACTH/beta-LPH precursor) from rat pars intermedia. (1980) (28)
Expression of the prohormone convertase PC2 correlates with the presence of corticotropin-like intermediate lobe peptide in human adrenocorticotropin-secreting tumors. (1994) (28)
Immunohistochemical localization of subtilisin/kexin-like proprotein convertases in human atherosclerosis (2005) (28)
Pilocarpine-induced seizures are accompanied by a transient elevation in the messenger RNA expression of the prohormone convertase PC1 in rat hippocampus: Comparison with nerve growth factor and brain-derived neurotrophic factor expression (1997) (28)
Specific cleavage of beta-LPH and ACTH by tonin: release of an opiate-like peptide beta-LPH (61-78). (1979) (27)
Characterization of multiple forms of porcine anterior pituitary proopiomelanocortin amino-terminal glycopeptide. (1982) (27)
Prostatic secretory protein PSP94: gene organization and promoter sequence in rhesus monkey and human. (1991) (27)
Maintained PC1 and PC2 expression in the AtT-20 variant cell line 6T3 lacking regulated secretion and POMC: restored POMC expression and regulated secretion after cAMP treatment. (1995) (27)
Localization of the human prostatic secretory protein PSP94 and its mRNA in the epithelial cells of the prostate. (1988) (27)
Identification and localization of 7B2 protein in human, porcine, and rat thyroid gland and in human medullary carcinoma. (1988) (27)
Reinvestigation of the disulfide bridge arrangement in human pro-opiomelanocortin N-terminal segment (hNT 1-76). (2009) (27)
Relationship between testosterone, estradiol and circulating PCSK9: Cross-sectional and interventional studies in humans. (2015) (26)
Effect of beta-lipotropin on aldosterone production in the isolated rat adrenal cell preparation. (1982) (26)
Proprotein convertases as therapeutic targets. (2008) (26)
Corticotropin (ACTH) and the N-terminal fragment of pro-opiomelanocortin are located in the same granules in cells of rat pituitary gland. (1983) (26)
Immunological characterization of β-lipotropin fragments (endorphin, β-MSH, and N-fragment) from fish pituitaries (1978) (26)
Characterization of β-endorphin immunoreactive peptides in rat pituitary and brain by coupled gel and reversed-phase high-performance liquid chromatography (1983) (26)
The ever-expanding saga of the proprotein convertases and their roles in body homeostasis: emphasis on novel proprotein convertase subtilisin kexin number 9 functions and regulation (2018) (26)
Selective cleavage of proenkephalin-derived peptides (less than 23,300 daltons) by plasma kallikrein. (1988) (25)
The cDNA structure of rat plasma kallikrein. (1989) (25)
Distribution and Regulation of Proconvertases PC1 and PC2 in Human Pituitary Adenomas (1999) (25)
Elevated expression of proprotein convertases alters breast cancer cell growth in response to estrogen and tamoxifen. (2001) (25)
Mice Fed a High‐Cholesterol Diet Supplemented with Quercetin‐3‐Glucoside Show Attenuated Hyperlipidemia and Hyperinsulinemia Associated with Differential Regulation of PCSK9 and LDLR in their Liver and Pancreas (2018) (25)
Fragmentation of bovine chromogranin A by plasma kallikrein. (1990) (24)
Presence of the Novel Pituitary Protein „7B2” in Bovine Chromaffin Granules: Possible Co‐Release of 7B2 and Catecholamine as Induced by Nicotine (1987) (24)
A β‐LPH PRECURSOR MODEL: RECENT DEVELOPMENTS CONCERNING MORPHINE‐LIKE SUBSTANCES (1977) (24)
Intranuclear Rodlets in the Substantia Nigra: Interactions with Marinesco Bodies, Ubiquitin, and Promyelocytic Leukemia Protein (2004) (24)
Processing of Two Forms of the Common Precursor to α‐Melanotropin and β‐Endorphin in the Rat Pars Intermedia (1980) (24)
Variable effects of gender and Western diet on lipid and glucose homeostasis in aged PCSK9‐deficient C57BL/6 mice 性别与西方饮食对CSK9基因缺陷的PC57BL/6老龄小鼠的脂质以及葡萄糖内稳态的不同影响 (2015) (24)
Secretory protein 7B2 is associated with pancreatic hormones within normal islets and some experimentally induced tumors. (1988) (24)
Chromosomal assignment of the genes for proprotein convertases PC4, PC5, and PACE 4 in mouse and human. (1995) (24)
Inhibitory activity and structural characterization of a C-terminal peptide fragment derived from the prosegment of the proprotein convertase PC7. (2000) (24)
The apoB-to-PCSK9 ratio: A new index for metabolic risk in humans. (2015) (23)
The ostrich pituitary contains a major peptide homologous to mammalian chromogranin A(1–76) (1990) (23)
Two-dimensional immunoblotting analysis and immunocytochemical localization of the secretory polypeptide 7B2 in adrenal medulla (1988) (23)
Prohormone Convertases in Mouse Submandibular Gland: Co-localization of Furin and Nerve Growth Factor (1997) (23)
Multiple endocrine neoplasia with Cushing's syndrome due to paraganglioma producing corticotropin-releasing factor and adrenocorticotropin. (1986) (23)
Tissue-specific expression of the prostatic secretory protein PSP94 in cynomolgus monkey (Macaca fascicularis. (1988) (23)
Purification and sequence determination of bovine atrial natriuretic factor. (1986) (23)
Proprotein convertases are important mediators of the adipocyte differentiation of mouse 3T3-L1 cells. (2002) (23)
Peptidyl substrates containing unnatural amino acid at the P'1 position are potent inhibitors of prohormone convertases. (2009) (22)
The prohormone and proprotein processing enzymes PC1 and PC2: structure, selective cleavage of mouse POMC and human renin at pairs of basic residues, cellular expression, tissue distribution, and mRNA regulation. (1992) (22)
Structure‐function studies on the biosynthesis and bioactivity of the precursor convertase PC2 and the formation of the PC2/7B2 complex (1995) (22)
Immunological identification and sequence characterization of a peptide derived from the processing of neuroendocrine protein 7B2 (1991) (22)
Regulation of carbonic anhydrase III by thyroid hormone: opposite modulation in slow- and fast-twitch skeletal muscle. (1987) (21)
Response of human aldosteronoma cells in culture to the N-terminal glycopeptide of pro-opiomelanocortin and gamma 3-MSH. (1983) (21)
Pro-opiomelanocortin-related peptides in cerebrospinal fluid: A study of manic-depressive disorder (1985) (21)
Complete sequence of the glycosylated amino terminal segment of porcine pro-opiomelanocortin. (2009) (21)
Effects of proopiomelanocortin-derived peptides, methionine-enkephalin and forskolin on the maturation of ovine fetal adrenal cells in culture. (1984) (21)
Purification of radiolabeled and native polypeptides by gel permeation high-performance liquid chromatography. (1982) (21)
Neuroanatomical and functional studies of peptide precursor-processing enzymes. (1991) (20)
Regional localization of three convertases, PC1 (Nec-1), PC2 (Nec-2), and furin (Fur), on mouse chromosomes. (1992) (20)
Substrate specificity of the enzyme tonin: cleavage of substance P (1980) (20)
Developmental Changes in Immunoreactive Content of Novel Pituitary Protein 7B2 in Human Pancreas and Its Identification in Pancreatic Tumors (1987) (20)
Processed forms of neuroendocrine proteins 7B2 and secretogranin II are found in porcine pituitary extracts. (2009) (20)
N-Terminal amino acid sequence of rat tonin: homology with serine proteases. (1978) (20)
Primary structure of mouse chromogranin B deduced from cDNA sequence. (1990) (20)
Increased stress-induced analgesia in mice lacking the proneuropeptide convertase PC2 (2006) (20)
Propressophysin is present in neurones at multiple sites in wistar and homozygous brattleboro rat brain (1986) (20)
Demonstration of the vasopressin associated glycopeptide in the brain and peripheral tissues of the Brattleboro rat (1986) (20)
My road to Damascus: how I converted to the prohormone theory and the proprotein convertases. (2012) (20)
Quantitative proteomic analysis of PCSK9 gain of function in human hepatic HuH7 cells. (2011) (19)
Expression of neuroendocrine secretory protein 7B2 mRNA in the mouse and rat pituitary gland. (1993) (19)
Concomitant changes of ACTH, beta-endorphin and N-terminal portion of pro-opiomelanocortin in rats. (1982) (19)
Differences of pancreatic expression of 7B2 between C57BL/6J and C3H/HeJ mice and genetic polymorphisms at its locus (Sgne1). (2006) (19)
Implications of the subtilisin/kexin-like precursor convertases in the development and function of nervous tissues. (1996) (19)
The loss-of-function PCSK9Q152H variant increases ER chaperones GRP78 and GRP94 and protects against liver injury. (2020) (19)
Of PCSK9, cholesterol homeostasis and parasitic infections: possible survival benefits of loss-of-function PCSK9 genetic polymorphisms. (2007) (19)
Mouse plasma kallikrein: cDNA structure, enzyme characterization, and comparison of protein and mRNA levels among species. (1990) (19)
Pan-neuronal mRNA expression of the secretory polypeptide 7B2 (1994) (18)
Regional distribution of a novel pituitary protein (7B2) in the rat spinal cord: Effect of neonatal capsaicin treatment and thoracic cord transection (1985) (18)
Assignment of the gene for neuroendocrine protein 7B2 (SGNE1 locus) to mouse chromosome region 2[E3-F3] and to human chromosome region 15q11-q15. (1990) (18)
Structural and immunological homology of human and porcine pituitary and plasma IRCM-serine protease 1 to plasma kallikrein: marked selectivity for pairs of basic residues suggests a widespread role in pro-hormone and pro-enzyme processing. (1988) (18)
Proprotein convertases as therapeutic targets (2008) (18)
Ethnic differences in the frequency of the cardioprotective C679X PCSK9 mutation in a West African population. (2008) (18)
Inhibition by beta-endorphin of dopamine-sensitive adenylate cyclase in rat striatum. (1977) (18)
Elevation of a novel pituitary protein (7B2) in the plasma in small cell carcinoma of the lung. (1989) (17)
Purification and partial chemical characterization of human pituitary lipolytic hormone. (1976) (17)
From beta-lipotropin to beta-endorphin and 'pro-opio-melanocortin'. (1979) (17)
Evidence for the release of a novel pituitary polypeptide (7B2) from the growth hormone-producing pituitary adenoma of patients with acromegaly. (1988) (17)
Complete amino acid sequence of a VLDV-type neurophysin from ostrich differs markedly from known mammalian neurophysins. (2009) (17)
Revised structure of sheep beta-lipotropic hormone. (2009) (17)
Coordinated regulation and colocalization of αv integrin and its activating enzyme proprotein convertase PC5 in vivo (2003) (17)
Primary structure and morphine-like activity of human beta-endorphin. (1977) (17)
Different processing of chromogranin B into GAWK-immunoreactive fragments in the bovine adrenal medulla and pituitary gland. (1988) (17)
On the isolation of human pituitary hormones. (1978) (17)
Metabolic clearance rate and half-time disappearance rate of human N-terminal and adrenocorticotropin of pro-opiomelanocortin in the rat: a comparative study. (1983) (16)
Purification of ovine placental lactogen (oPL) using high‐performance liquid chromatography (1986) (16)
Light and electron microscopic immunocytochemistry of β-endorphin/β-LPH-like immunoreactive neurons in the arcuate nucleus and surrounding areas of the rat hypothalamus (1985) (16)
Radioimmunoassay of ovine beta-lipotropic hormone. (1972) (16)
Expression and transient nuclear translocation of proprotein convertase 1 (PC1) during mouse preimplantation embryonic development (2005) (16)
Aminoethyl benzenesulfonyl fluoride and its hexapeptide (Ac‐VFRSLK) conjugate are both in vitro inhibitors of subtilisin kexin isozyme‐1 (2004) (16)
A novel pituitary protein (7B2)-like immunoreactivity is secreted by a rat phaeochromocytoma cell line (PC12). (1986) (16)
Effects of rs6234/rs6235 and rs6232/rs6234/rs6235 PCSK1 single-nucleotide polymorphism clusters on proprotein convertase 1/3 biosynthesis and activity. (2011) (16)
Cataleptic Effect of 61-91 Beta-Lipotropic Hormone in Rat (1977) (15)
PCSK2-null mice exhibit delayed intestinal motility, reduced refeeding response and altered plasma levels of several regulatory peptides. (2011) (15)
The LIM homeobox protein mLIM3/Lhx3 induces expression of the prolactin gene by a Pit‐1/GHF‐1‐independent pathway in corticotroph AtT20 cells (1998) (15)
Expression of the neuroendocrine cell marker 7B2 in human ACTH secreting tumours (1992) (15)
β2‐Inhibin contains the active core of human seminal plasma β‐inhibin: synthesis and bioactivity (1985) (15)
Genetic deficiency for proprotein convertase subtilisin/kexin type 2 in mice is associated with decreased adiposity and protection from dietary fat-induced body weight gain (2010) (15)
In vitro biosynthesis of gamma-lipotropic hormone. (1976) (15)
Isolation and primary structure of novel neurointermediate pituitary peptides derived from the C-terminal of the rat vasopressin-neurophysin precursor (propressophysin). (1986) (15)
Effects of several pro-opiomelanocortin derived peptides on steroidogenesis in ovine and bovine adrenal cells. (1985) (14)
Immunohistochemical localization of human pituitary glycopeptide (HPGP)-like immunoreactivity in the hypothalamus and pituitary of normal and homozygous diabetes insipidus (Brattleboro) rats. (1982) (14)
From Proopiomelanocortin to Cancer (1993) (14)
Isolation and amino-acid sequence of beta-LPH from sheep pituitary glands. (1965) (14)
Reinvestigation of the N-terminal amino acid sequence of beta-lipotropin from human pituitary glands. (1981) (14)
Immunoreactive β-Endorphin in the Rat Mammotropic Transplantable Tumor (MtT-F4) (1978) (13)
Precursor polyproteins in endocrine and neuroendocrine systems. (2009) (13)
NH2-terminal specificity and axonal localization of adrenocorticotropin binding sites in rat median eminence. (1985) (13)
β‐Estradiol results in a proprotein convertase subtilisin/kexin type 9‐dependent increase in low‐density lipoprotein receptor levels in human hepatic HuH7 cells (2015) (13)
Immunocytochemical investigation of insulin secretion by pancreatic beta-cells in control and diabetic Psammomys obesus. (1995) (13)
Morphine-like activity of sheep β-lipotropin and of its tryptic fragments (1977) (13)
A Fluorogenic Peptide Containing the Processing Site of Human SARS Corona Virus S‐Protein: Kinetic Evaluation and NMR Structure Elucidation (2007) (13)
Novel approach to rapid and sensitive localization of protein disulfide bridges by high-performance liquid chromatography and electrochemical detection (1985) (13)
Isolation and characterization of four proteases from porcine pituitary neurointermediate lobes: Relationship to the maturation enzyme of prohormones (1985) (12)
Two glycosylation sites on the N‐terminal segment of porcine pars distalis pro‐opiomelanocortin (1980) (12)
Lipolytic and hypocalcemic effects of sheep beta-lipotropic hormone. (1970) (12)
Dynamics of 7B2 and galanin expression in solitary magnocellular hypothalamic vasopressin neurons of the homozygous Brattleboro rat (1992) (12)
Two large glycoprotein fragments related to the NH2-terminal part of the adrenocorticotropin-beta-lipotropin precursor are the end products of the maturation process in the rat pars intermedia. (1980) (12)
The pituitary polypetide “7B2” is associated with LH/FSH and TSH cells and is localized within secretory vesicles (1987) (12)
Cyclical edema and hypokalemia due to occult episodic hypercorticism. (1987) (12)
Expression of variant forms of proopiomelanocortin, the common precursor to corticotropin and beta-lipotropin in the rat pars intermedia. (1981) (12)
Complete amino acid sequence of human seminal plasma beta-inhibin. Prediction of post Gln-Arg cleavage as a maturation site. (1984) (12)
Enzymatic cleavage of pro‐opiomelanocortin by anterior pituitary granules (1983) (12)
Effects of glacial acetic acid on the extraction, chemical stability, and biological activities of beta-LPH. (1970) (11)
White Adipose Tissue Surface Expression of LDLR and CD36 is Associated with Risk Factors for Type 2 Diabetes in Adults with Obesity (2020) (11)
The production of the ostrich NH2-terminal POMC fragment requires cleavage at a unique signal peptidase site (1993) (11)
Ontogeny of a novel pituitary protein (7B2) in the human fetal intestine (1985) (11)
Effects of peptides of pituitary origin on the formation of C21 steroid by fetal calf adrenal cells in culture. (1977) (11)
Immunoreactivity of vasopressin and a novel pituitary protein ‘7B2’ in long-evans and brattleboro rat hypothalamus and hypophysis (1985) (11)
Immunocytochemistry of the C-terminal peptide of propressophysin (CPP): Relationship to vasopressin, oxytocin and neurophysin (1983) (11)
Depolarizing Action of Secretory Granule Protein 7B2 on Rat Supraoptic Neurosecretory Neurons (1993) (11)
Melanin concentrating hormone. V. Isolation and characterization of alpha-melanocyte-stimulating hormone from frog pituitary glands. (1989) (11)
Expression of the diversity of neural and hormonal peptides via the cleavage of precursor molecules (1989) (11)
Amino Terminal Sequence of 7B2: A Novel, Human Pituitary/Brain Polypeptide Present in Gonadotrophs and Released by LHRH (1987) (11)
Associations Between Soluble LDLR and Lipoproteins in a White Cohort and the Effect of PCSK9 Loss-of-Function (2018) (11)
FRAGMENT OF SHEEP BETA-LIPOTROPIN WITH MORPHINE-LIKE ACTIVITY (1976) (10)
Human NH2 terminal of pro-opiomelanocortin as a potential marker for pulmonary carcinoma. (1983) (10)
The complete amino acid sequence of rat submaxillary gland tonin does contain the aspartic acid at the active site: confirmation by protein sequence analyses (1987) (10)
Isolation and partial characterization of a biosynthetic N-terminal methionyl peptide of bovine pars intermedia: relationship to ubiquitin. (1978) (10)
Circular dichroism studies of sheep beta-lipotropic hormone. (1976) (10)
Implications of proprotein Convertase 5 (PC5) in the arterial restenotic process in a porcine model. (2004) (10)
Analgesic action of chronic high levels of endogenous neuropeptides in rats bearing the MtT-F4 tumor. (1980) (10)
A NOVEL PITUITARY PROTEIN (7B2) IN THE RAT UROGENITAL TRACT (1985) (10)
Fat Cell Adenylate Cyclase Activation by Sheep β-Lipotropic Hormone 1 (1972) (10)
Correct processing and secretion of a human prostatic secretory protein (PSP94) in Escherichia coli. (1988) (10)
ANF (Arg 101--Tyr 126) is the peptide secreted by rat atrial cardiocytes in culture. (1985) (10)
How the Prohormone Theory Solved Two Important Controversies in Hormonal and Neural Peptide Biosynthesis (2013) (10)
Microsequencing evidence for the maturation of human proopiomelanocortin into an 18 amino acid β-melanocyte stimulating hormone [hβMSH(5–22)] in nonpituitary tissue (1989) (10)
Effect of pituitary tumor MtT-F4 on carnitine levels in the serum, liver and heart of rats. (1981) (10)
Dependence of tonin activity in rat submaxillary gland on growth hormone and testosterone. (1977) (9)
Ultrastructural localization of secretory granule constituent chromogranin and 7 B 2. (1988) (9)
7B2, a possible marker for nonfunctioning pancreatic islet cell tumor. (1991) (9)
Immunohistochemical localization of γ-melanocyte-stimulating hormone in the rat pituitary gland (1981) (9)
The production by alternate splicing of two mRNAs differing by one codon could be an intrinsic property of neuroendocrine protein 7B2 gene expression in man. (1991) (9)
Syntheses of argininal semicarbazone containing peptides and their applications in the affinity chromatography of serine proteinases. (2009) (9)
Rat plasma kallikrein: purification, NH2-terminal sequencing and development of a specific radioimmunoassay. (1989) (9)
The major 40-kDa glycoprotein in human prostatic fluid is identical to Zn-alpha 2-glycoprotein. (1987) (8)
Elevation of plasma 7B2 (a novel pituitary protein) in cord blood at obstetrical delivery and the possible correlation with GH. (1987) (8)
Functional diversity of bioactive peptides in the nervous system itself: “How the brain may understand” (1989) (8)
Lower plasma PCSK9 in normocholesterolemic subjects is associated with upregulated adipose tissue surface‐expression of LDLR and CD36 and NLRP3 inflammasome (2021) (8)
ANF mRNA IS DETECTED BY THE POLYHERASE CHAIN REACTION TECHNIQUE IN THE CHORIOIDRA AND CILIARY BODIES BUT NOT IN THE RETINA OF THE RAT EYE (1991) (8)
Assignment of secretogranin I locus to mouse chromosome 2 by in situ hybridization and interspecific backcross analysis. (1991) (8)
Evidence for a signal sequence at the N terminus of the common precursor to adrenocorticothrophin and beta-lipotropin in mouse pituitary cells. (1981) (8)
Molecular heterogeneity of pro-atrial natriuretic factor. (1989) (8)
The metabolism of -amyloid converting enzyme and -amyloid precursor protein processing (2004) (8)
Beta‐endorphin and beta‐lipotropin secretion by an acth‐secreting mouse pituitary tumor (1978) (7)
Malaria severity: Possible influence of the E670G PCSK9 polymorphism: A preliminary case-control study in Malian children (2018) (7)
Purification and primary structure of pro-aldosterone secretion inhibitory factor from bovine adrenal chromaffin cells. (1989) (7)
Peptides related to the N-terminus of pro-opiomelanocortin in the human adrenal medulla. (1989) (7)
Application of high-performance liquid chromatography to characterize radiolabeled peptides for radioimmunoassay, biosynthesis, and microsequence studies of polypeptide hormones. (1983) (7)
Light and electron microscopic immunocytochemical localization of adrenocorticotrophin-like activity in rat cerebellar and red nuclei (1981) (7)
Detection of endopeptidase activity and analysis of cleavage specificity using a radiometric solid-phase enzymatic assay. (1991) (7)
Biosynthesis of hormonal and neural peptides. (1984) (7)
Expression and sorting of rat plasma kallikrein in POMC-producing AtT-20 cells. (1991) (7)
Immunohistochemical localization of beta-lipotropic hormone in the pituitary gland. (1977) (7)
Effects of pituitary -LPH on blood platelets and coagulation in rabbits. (1971) (7)
Radiolabeled biotinyl peptides as useful reagents for the study of proteolytic enzymes. (1993) (7)
Development of hyperlipidemia associated with increased lipolytic response of isolated adipose tissue cells following prolonged stimulation by an ectopic pituitary tumor. (1978) (6)
Processing of Peptide Hormone and Neuropeptide Precursors1 (1984) (6)
Effects of angiotensin infusions on urinary excretion of compound III and substances other than aldosterone. (1962) (6)
CHEMICAL CHARACTERIZATION OF RAT αMSH/ß‐ENDORPHIN PRECURSOR FROM PARS INTERMEDIA (1980) (6)
Subcellular fractionation of pituitary neurointermediate lobes: revelation of various basic proteases. (1984) (6)
Synergistical effects of ovine corticotropin-releasing factor (CRF) and arginine vasopressin (AVP) on the release of pro-opiomelanocortin (POMC) related peptides by pituitary adenoma of a patient with Nelson's syndrome in vitro. (1984) (6)
13 The pituitary polypeptide "7B2" is associated with LH/FSH and TSH cells and is also found in the CNS and in the peripheral neuroendocrine system : An immunocytochemical study. (1986) (6)
LHRH increases plasma 7B2 concentration in normal human subjects. (1989) (6)
Isoquercetin as an Anti-Covid-19 Medication: A Potential to Realize (2022) (6)
The metabolism of beta-amyloid converting enzyme and beta-amyloid precursor protein processing. (2004) (6)
ISOLATION AND NH 2 -TERMINAL SEQUENCE OF A HIGHLY CONSERVED PITUITARY AND HYPOTHALAMIC PROTEIN BELONGING TO A NEW SUPERFAMILY (1983) (6)
The enigma of soluble LDLR: could inflammation be the key? (2020) (6)
Modification of Cunningham's method for the detection of proteases in tissue sections. (1977) (6)
Changes of endocrine properties of a transplantable, multihormonal, pituitary tumor (MtT-F4) after hypophysectomy of host rats. (1975) (6)
Inhibition of binding of ovine placental lactogen to growth hormone and prolactin receptors by monoclonal antibodies. (1986) (6)
Lipogenic activity of a potent lipolytic hormone: sheep lipotropin ( -LPH). II. Further effects of sheep -LPH on specifically labeled glucose and the localization of lipogenic active center of the molecule. (1972) (6)
Enzymatic maturation of pro-opiomelanocortin by anterior pituitary granules. Methodological approach leading to definite characterization of cleavage sites by means of high-performance liquid chromatography and microsequencing. (1983) (6)
Biosynthesis of a ubiquitin-related peptide in rat brain and in human and mouse pituitary tumors. (1978) (6)
From proopiomelanocortin to cancer. Possible role of convertases in neoplasia. (1993) (5)
ANF mRNA is detected by the polymerase chain reaction technique in the chorioidea and bodies but not in the retina of the rat eye. (1991) (5)
Inhibition of release of a novel pituitary polypeptide, 7B2, follicle-stimulating hormone, and luteinizing hormone from rat anterior pituitary cells in vitro by human beta-inhibin. (1986) (5)
The messenger RNA for pituitary protein 7B2 is widely expressed in mouse CNS and castration reduces its pituitary level (1991) (5)
Chemical characterization of adrenocorticotropin and a novel peptide biosynthesized from a pituitary adenoma of a patient with Cushing's disease. (1980) (5)
Distribution of a novel pituitary protein (7B2) in mammalian gastrointestinal tract and pancreas (1988) (5)
Cell-free synthesis of porcine proopiomelanocortin: two distinct primary translation products. (1983) (5)
Primary structure of the ovine pituitary follitropin beta-subunit. (1981) (5)
IN VITRO BIOSYNTHESIS AND CHEMICAL CHARACTERIZATION OF ACTH AND ACTH FRAGMENTS BY THE RAT PARS INTERMEDIA (1980) (5)
The primary structure of human β‐lipotropin (1982) (5)
A chimeric proinsulin-CD5 protein expressed in AtT-20 cells is directed to the cell surface via the constitutive pathway. (1995) (5)
Affinity purification of proteinases by a combination of immobilized peptidyl aldehyde and semicarbazone. (1992) (5)
Purification and partial chemical characterization of sheep neurophysin. (1973) (5)
Multipotent lipotropic hormones. In search of a pituitary cell producing multipotent LPH. (1975) (5)
Targeted production of proprotein convertase PC1 enhances mammary development and tumorigenesis in transgenic mice. (2009) (5)
Peptides of the neurointermediary lobe of rat pituitary stimulate GH secretion in vitro (1983) (5)
Lipogenic activity of a potent lipolytic hormone: sheep beta lipotropin (beta-LPH). A comparative study of the effects of beta-LPH and insulin on in vitro glucose metabolism of adipose tissue. (1970) (5)
Relationships between calcium transport and the lipolytic effect of sheep -lipotropic hormone ( -LPH) in adipose tissue. (1972) (5)
Ultrastructural investigation of ACTH immunoreactivity in arcuate and supraoptic nuclei of the rat (2004) (5)
Rat beta-LPH, gamma-LPH and beta-endorphin biosynthesized by isolated cells of pars intermedia and pars distalis. Further characterization. (2009) (5)
LDL cholesterol PCSK 9 A Key Modulator of Cardiovascular Health (2014) (4)
Characterization of a repressor element in the promoter region of proprotein convertase 2 (PC2) gene. (2002) (4)
Severity of coeliac disease and clinical management study when using a CYP3A4 metabolised medication: a phase I pharmacokinetic study (2020) (4)
Association of the rs562556 PCSK9 Gene Polymorphism with Reduced Mortality in Severe Malaria among Malian Children (2020) (4)
Differences of Pancreatic Expression of 7 B 2 Between C 57 BL / 6 J and C 3 H / HeJ Mice and Genetic Polymorphisms at its locus ( Sgne 1 ) (2006) (4)
[Endorphins: structure, roles and biogenesis]. (1981) (4)
(Can. J. Physiol. Pharmacol., 58:767-771)Liver lipid metabolism and effect of cholesterol-lowering agents in the hyperlipidemia induced in rats by implantation of the pituitary derived MtT-F4 tumor (1980) (4)
The role of the NH2-terminal portion of pro-opiomelanocortin as a biomarker for human lung cancer. (1987) (4)
Allelic clustering and ancestry-dependent frequencies of rs6232, rs6234, and rs6235 PCSK1 SNPs in a Northern Ontario population sample (2012) (4)
On the circulating form of atrial natriuretic factor. (1985) (4)
The prohormone theory and the proprotein convertases: it is all about serendipity. (2011) (4)
Peptide mapping of 125I-labelled membrane protein of influenza viruses by reverse-phase high-performance liquid chromatography. (1982) (4)
Identification, Purification, and Characterization of the Molecular Forms of Aplysia californica Peptidylglycine α‐Amidating Enzyme (1996) (4)
Biosynthesis of β-Endorphin in the Rat Pars Intermedia (1980) (4)
Immunocytochemical localization of a novel pituitary polypeptide “7B2” in the gastro-intestinal tract of the rat (1987) (4)
Hyperlipoproteinemia induced by a transplantable pituitary tumor in the rat. (1979) (4)
Processing of two forms of the common precursor to alpha-melanotropin and beta-endorphin in the rat pars intermedia. Evidence for and partial characterization of new pituitary peptides. (1980) (3)
Effects of pro-opiomelanocortin fragments on release of catecholamines from adrenal chromaffin cells (1982) (3)
A rapid high-performance liquid chromatography purification method of iodinated polypeptide hormones. (1980) (3)
ApoB-lipoproteins and PCSK9 as Modulators of Human White Adipose Tissue Function and NLRP3 Inflammasome Activity (2018) (3)
From the Prohormone Theory to Proopiomelanocortin and (2016) (3)
Role of convertases in the processing of neuropeptides and neurotrophins (1996) (3)
Lipolytic response, cyclic AMP and cyclic GMP accumulation in rat adipocytes stimulated with ACTH: effect of MtT-F4 tumor and clofibrate treatment. (1979) (3)
Newer Advances in the Pathogenesis of Human Hypertension: The Adrenal Cortex and Renal Pressor Mechanism. (1961) (3)
The Pituitary and Hypertension (1984) (3)
Structure and maturation process of pro-opiomelanocortin: a model for other neuropeptides. (1980) (3)
[Prader-Willi-Labhart syndrome: relations with the hypothalamus and chromosome 15]. (1990) (3)
Detection from rat pituitary of beta-lipotropin and materials containing opiatelike activity by combined enzymatic radioreceptor assay. (1981) (3)
Primary hyperaldosteronism: a pituitary--adrenal dysfunction related to a new pituitary glycopeptide? (1982) (3)
Genetic Mapping of the Gene for SKI-1/S1P Protease (locus Symbol Mbtps 1) to Mouse Chromosome 8 (2002) (3)
Effect of somatostatin on growth hormone release by MtT-F4 rat pituitary tumor in vitro. (1977) (3)
Renin-angiotensin system in chronically hypophysectomized rats. (1972) (3)
Biosynthesis of f-endorphin from f 3-lipotropin and a larger molecular weight precursor in rat pars intermedia ( endogenous opiates / prohormones / corticotropin / radiolabeled peptide sequencing / pituitary gland ) (3)
[In vitro biosynthesis of bovine beta-lipotropic hormone]. (1974) (3)
The Jeremiah Metzger Lecture. From POMC to functional diversity of neural peptides: the key importance of convertases. (1991) (3)
Cathepsin-B fusion proteins misroute secretory protein partners such as the proprotein convertase PC2-7B2 complex toward the lysosomal degradation pathways. (2000) (3)
Beta-lipotropin precursor of beta-MSH and beta-endorphin. (1979) (2)
[Acromegaly and empty sella turcica]. (1975) (2)
Proteomic analysis of neuroendocrine peptidergic system disruption using the AtT20 pituitary cell line as a model. (2008) (2)
Immunological characterization of beta-lipotropin fragments (endorphin, beta-MSH, and N-fragment) from fish pituitaries. (1978) (2)
Distribution pattern in the human pituitary and hypothalamus of a new neuropeptide: The C-terminal glycoprotein-fragment of human pro-pressophysin (CPP) (2004) (2)
Amino acid sequence of rabbit kidney neutral endopeptidase 24.11 (enkephalinase) deduced from a complementary DNA. (1987) (2)
Effect of clofibrate treatment on chronic hyperlipidemia induced by an ACTH-producing tumor. (1977) (2)
Biochemical aspects of a new hormone: rat atrial natriuretic factor (rANF). (1985) (2)
Species specificity of the inhibition of adenylate cyclase activation by products of ACTH-stimulated fat cells. (1973) (2)
Characterization of N-terminal fragment of proopiomelanocortin in cerebrospinal fluid. (1987) (2)
[Endorphins 1989: neuroendocrine aspects]. (1989) (2)
Urinary molecular forms of human N-terminal of proopiomelanocortin: possible deglycosylation and degradation by the kidney. (1984) (2)
Lipotropic and adrenocorticotropic hormones. Biological activities of the carboxyl-modified hormones. (1974) (2)
A novel human pituitary peptide containing the gamma-MSH sequence. (1980) (2)
3889 : FURTHER OBSERVATIONS ON THE BURROWING OWL Athene cunicularia IN FRENCH GUIANA (2008) (2)
Morphine-like activity of sheep beta-lipotropin and of its tryptic fragments. (1977) (1)
Cyclic nucleotides and platelet aggregation in hypertensive rats with ectopic pituitary tumor. (1980) (1)
Endoproteolysis in health and diseases—implications of proprotein convertases (PCs) (2005) (1)
Purification of Radiolabeled and Native Polypeptides by Gel Permeation High-Performance Liquid Chromatography1 (1983) (1)
3 – Biosynthesis of β-Endorphin from Proopiomelanocortin (1981) (1)
Endorphins in Fetomaternal Physiology (1985) (1)
The complete amino acid sequence of rat submaxillary gland tonin does contain the aspartic acid at the active site: confirmation by protein sequence analysis. (1987) (1)
[Beta-endorphin induced akinesia in rats: a pharmacological study (author's transl)]. (1979) (1)
An aldosterone stimulating agent: a novel human pituitary hormone from pro-opiomelanocortin. (1981) (1)
Gene expression of peptides: the pro-opiomelanocortin model. (1982) (1)
Gene expression of novel prohormone convertases in rat spinal cord (1992) (1)
[Decrease in the immunoreactivity of protein 7B2 in vasopressinergic cells in the supraoptic nucleus and in fibers of the neurohypophysis, in Brattleboro rats]. (1988) (1)
Morphine Dependence and Its Effect on β-Endorphin Biosynthesis by the Rat Neurointermediate Lobe1 (1981) (1)
Effects of morphine and ethanol tolerance and withdrawal on pituitary endorphin-like immunoreactivity (1980) (1)
Higher Adipose Tissue Surface-expression of LDLR and CD36 and Risk Factors for T2D in Normocholesterolemic Subjects with Low Plasma PCSK9 (2018) (1)
Design of octadecapeptide loop structures by modeling the active-site region of barley serine proteinase inhibitor-2 (1994) (1)
Erratum: Potentiation of carbon monoxide-induced relaxation of rat aorta by YC-1 (2000) (1)
Binding inhibition by monoclonal antibodies of ovine placental lactogen to growth hormone receptors in human liver (1986) (1)
In vivo bioassay of ACTH: new developments. (1970) (1)
Obesity and pituitary lipolytic hormones. (1974) (1)
Structural and biochemical investigation of heptad repeat derived peptides of human SARS corona virus (hSARS-CoV) spike protein. (2008) (1)
Urinary levels of immunoreactive NH2-terminal of pro-opiomelanocortin in patients with malignant pulmonary disease. (1989) (1)
A Highly Selective Cell Permeable Peptide Inhibitor of Proprotein Convertase 1: Design, Synthesis and Biological Evaluation in Cellular PC1-Mediated Proteolysis (2001) (1)
The Biological Relevance of PCSK9: When Less Is Better…. (2022) (1)
Synthesis of the segment (11-23) located in the first tandem repeat of plasma kallikrein: comparative binding studies of this and another segment (328-343) to high-molecular-mass kininogen. (1993) (1)
[Biosynthesis of beta-endorphin]. (1978) (1)
Functional aspects of multitransmitter neurons. Studies of interactions among pro-opiomelanocortin products. (1987) (1)
Partial sequence of trypsin inhibitior from ovumucoid. (1973) (1)
Isolation of a new lipolytic-melanotropic peptide from human pituitary glands. (1976) (1)
APPG secretion in a rat phaeochromocytoma cell line (PC12) (1984) (1)
Immunohistochemical localization of gamma-melanocyte-stimulating hormone in the rat pituitary gland. (1981) (1)
beta 2-Inhibin contains the active core of human seminal plasma beta-inhibin: synthesis and bioactivity. (1985) (1)
PRO-OPIOMELANOCORTIN: A NEW CONCEPT ISSUED FROM ACTH AND LPH BIOSYNTHETIC STUDIES (1980) (1)
BIOSYNTHESIS AND MATURATION OF PRO-OPIOMELANOCORTIN (1981) (1)
Thyrotropin releasing hormone (TRH)-induced release of 7B2 (neuroendocrine polypeptide) in vivo and in vitro using adenoma cells of a patient with acromegaly. (1991) (1)
[Pituitary lipotropins (LPH)]. (1973) (1)
Comparing expression and activity of PCSK9 in SPRET/EiJ and C57BL/6J mouse strains shows lack of correlation with plasma cholesterol☆ (2016) (1)
Regulation of Carcinogenesis , Angiogenesis and Metastasis by the Proprotein Convertases ( PCs ) (2013) (1)
[Biosynthesis of polypeptide hormones]. (1980) (1)
Lipotropin and related peptides (1978) (1)
Request for hormone-producing tumour material. (1969) (0)
APPG-distribution in rat spinal cord: Evidence of an APPG-containing ascending pathway (1984) (0)
Isolation and Purification of Escherichia coli Heat-Stable Enterotoxin of Porcine Origin 1 (1983) (0)
Peptide Separation Using Guanidine-Hcl During Reverse-Phase High Performance Liquid Chromatography (1985) (0)
Allelic clustering and ancestry-dependent frequencies of rs6232, rs6234, and rs6235 PCSK1 SNPs in a Northern Ontario population sample (2012) (0)
Experimental hyperlipidemia in rats. (1979) (0)
In vitro biosynthesis of f 3-endorphin , y-lipotropin , and f 3-lipotropin by the pars intermedia of beef pituitary glands ( endogenous opiates / peptide hormones / prohormones / Edman degradation ) (0)
Mechanisms required to ensure research integrity (2011) (0)
Soluble LDLR Associates with Multiple Lipoprotein Parameters in a Caucasian Population and its Association with Serum PCSK9 is Affected by PCSK9 Loss of Function (2018) (0)
[Cancer of the ovaries]. (1952) (0)
Value of plasma NH2-terminal fragment of pro-opiomelanocortin in marking human lung cancer in various clinical settings. (1989) (0)
Morphine-like substances and the pituitary gland. (1976) (0)
Functional Aspects of Multitransmitter Neurons (1987) (0)
TRANSPORT OF EXOGENOUS BETA-LIPOTROPIN (ß-LPH) FROM THE PITUITARY TO THE CENTRAL NERVOUS SYSTEM OF THE RAT (1981) (0)
Macrophages express mRNAs for nerve growth factor and for convertases furin and PC1 in the lesined sciatic nerve (1995) (0)
Mammalian pro-hormone convertase (1997) (0)
A novel pituitary protein 7B2 in humanj pheochromocytoma : in vivo and in vitro study (1990) (0)
Immunoreactive beta-endorphin in the rat mammotropic transplantable tumor (MtT-F4). (1978) (0)
ANATOMICAL STUDIES OF NEUROPEPTIDE PRECURSOR PROCESSING ENZYMES (1992) (0)
[Antidiuretic effect of clofibrate in diabetes insipidus]. (1971) (0)
Testis-Specific Proprotein Convertase 4: Gene Structure, Optional Exons, and mRNA Isoforms (1994) (0)
Severity of coeliac disease and clinical management study when using a non-metabolised medication: a phase I pharmacokinetic study (2023) (0)
MATURATION OF THE COMMON PRECURSOR FOR BETA-ENDORPHIN AND ALPHA-MSH IN THE RAT PARS INTERMEDIA (1980) (0)
Studies of the Pathogenesis of Human Hypertension (2020) (0)
Request for hormone-producing tumour material. (1968) (0)
Chemical characterization of rat alpha MSH/beta-endorphin precursor from pars intermedia. (1980) (0)
Implication of prohormone convertates in the precursor processing of neuropeptides, hormones and growth factors: experimental and developmental models of the central and peripheral nervous system (1995) (0)
Abstract 216: PCSK9 Loss-of-Function Mutation Q152H is Associated with Reduced Dietary Fat Clearance and Insulin Resistance in Humans (2014) (0)
Microsequence of Polypeptide Hormones: Its Usefulness to Monitor the Isolation of Novel Molecules (1985) (0)
[Physiological roles of endorphins in 1987]. (1988) (0)
Discovery of the Proprotein Convertases and their Inhibitors (2006) (0)
Antiviral activity of quercetin-3-β-O-D-glucoside against Zika virus infection (2017) (0)
Proprotein Convertases in Tumorigenesis, Angiogenesis and Metastasis (2006) (0)
[Recent progress in endocrinology. Polypeptide hormones]. (1972) (0)
BIOSYNTHESIS OF BETA-ENDORPHIN AND ALPHA-MSH IN THE PARS INTERMEDIA OF RAT PITUITARIES (1980) (0)
Identification, purification, and characterization of the molecular forms of Aplysia californica peptidylglycine alpha-amidating enzyme. (1996) (0)
[Corticoadrenal insufficiency (Addison's disease)]. (1984) (0)
The enigma of soluble LDLR: could inflammation be the key? (2020) (0)
Detection of prohormone convertases in developing and adult mouse submandibular glands (1994) (0)
Diversity and Gene Expression (1988) (0)
Erratum: In vitro biosynthesis of γ-lipotropic hormone (1976) (0)
[In vitro biosynthesis of beta-lipotropin in brain tissue]. (1979) (0)
EFFECT OF MORPHINE OR ALCOHOL TREATMENT ON THE BIOSYNTHESIS OF β-ENDORPHIN BY THE NEUROINTERMEDIATE LOBE (1981) (0)
New perspectives in neuropeptides. Biosynthesis from large precursors. The pro-opio-melanocortin model in the pars intermedia. (1980) (0)
[The pituitary and morphinomimetic peptides]. (1977) (0)
In vitro biosynthesis of f 3-endorphin in pituitary glands ( ft-lipotropin / endogenous opiate / peptide with morphine-like activity / hormone ) (0)
Atrial natriuretic factor: isolation, identification, biological and pharmacological actions. (1985) (0)
Blockers of PCSK9 Ribosome Synthesis: Computational Predictions and in Vitro Confirmation (2022) (0)
The Atrial Natriuretic Factor Purification, Isolation of the Peptide and of Prepro ANF, and Physiological Studies (1986) (0)
PROCESSING OF PRO-OPIOMELANOCORTIN IN RAT, PORCINE AND HUMAN PITUITARIES (1981) (0)
The Question of Availability: Grain Processing Corp. v. American Maize-Products Co. (2002) (0)
Structure Analysis and Maturation of Pro-Opiomelanocortin in Rat Pars intermedia (1980) (0)
Sequence determination of a protein with N-terminal glutamic acid after modification of carboxyl groups with carbodiimide as the coupling agent. (1974) (0)
Profile of a quick assembly system including walls used as construction element, such as the top plate of a closure hatch panel, a floor; walls or slabs built with this profile (1982) (0)
The primary structure of human beta-lipotropin. Further peptide sequencing resolves the controversy and suggests the existence of only one human beta-lipotropin. (1982) (0)
[Pulmonary neoplasms and adrenal gland insufficiency: study of a case and hypothesis on an ACTH-inhibiting factor (ACTH-IF) or an abnormal ACTH secreted by the tumor]. (1973) (0)
Beta-endorphin induced akinesia in rats: effect of apomorhine and alpha-methyl-p-tyrosine and related modifications of dopamine turnover in the basal ganglia. (1977) (0)
Proinsulin-like peptide in porcine anterior pituitary: Purification and NH2-terminal sequence (1983) (0)
Characterization of beta-endorphin immunoreactive peptides in rat pituitary and brain by coupled gel and reversed-phase high-performance liquid chromatography. (1983) (0)
The propeptide Asnt ' Tyr 126 is the storage form of rat atrial natriuretic factor (2005) (0)
Characterization of peptides derived from pro-opiomelanocortin in the biological fluids of a patient with Nelson's syndrome. (1985) (0)
[Blood cortisol in neoplasm cases]. (1971) (0)
Light and electron microscopic localization of the N-terminal fragment of human pro-opiomelanocortin in the human pituitary gland and in neoplasms (2004) (0)
[The French Language Medical Association of Canada and medical research]. (1979) (0)
Isolation, Sequence and Cytochemical Localization of a Conserved Novel Pituitary-Hypothalamic Protein (1984) (0)
Request for hormone-producing tumour material. (1968) (0)
Enzymic characterization ofmurine andhumanprohormone convertase-1 (mPC1 andhPC1) expressed inmammalian GH4C1 cells (1993) (0)
Inhibition of sterol regulatory element-binding protein cleavage by the prodomain of human SKI-1 protease (2000) (0)
LOCAL FORCE DISTRIBUTION INFLUENCES CELL POLARITY AND DIRECTED MIGRATION IN ENDOTHELIUM (2004) (0)
MECHANICAL FORCE DETERMINES CELL POLARITY AND DIRECTED MIGRATION IN ENDOTHELIUM (2004) (0)
[The IRCM: a model of organization in the quest for scientific excellence. Interview by Robert Henry]. (1988) (0)
Modification of Cunningham's method for the detection of proteases in tissue sections. (1975) (0)
VASCULAR SMOOTH MUSCLE CELL RESPONSES TO MECHANICAL STIMULI (2004) (0)
[The Scientific, Achievement Prize to Dr. Claude Fortier]. (1982) (0)
Amino Acid Sequence of the Alpha and Beta Subunits of Ovine Pituitary Follitropin (FSH) (1982) (0)
Genetic Deficiency for Proprotein Convertase 2 (PC2) in Mice is Protective form Age and Diet-induced Obesity. (2008) (0)
[Medical research: an absolute necessity and not a tollerated luxury]. (1974) (0)
[Endorphins: structure, role and biogenesis]. (1983) (0)
Soluble LDLR is Reduced by Statin Therapy; Exploration of the Modulation of LDLR Shedding as a Mechanism of Action of an Established Lipid Therapy (2018) (0)
Tumorigenicity Platelet-derived Growth Factor-A-induced Functions and Convertase Family Is Functionally Correlated to by Members of the Proprotein 86 Factor-A at RRKR The Proteolytic Processing of Pro-Platelet-derived Growth (2003) (0)
Intracellular Proprotein convertase subtilisin/kexin type 9: Recruitment and regulatory role in mitochondrial architecture and bioenergetic (2022) (0)
Lipolytic activity of rat pituitaries in vitro. (1973) (0)
Felodipine and fexofenadine absorption and metabolism in celiac disease patients (2018) (0)
Paired basic amino acid convertases of pro-hormones and pro-proteins (1992) (0)
Neuronal and Endocrine Peptides (1988) (0)
IRCM‐Serine Protease # 1 from Pituitary and Heart A Common Prohormone Maturation Enzyme (1987) (0)
The Possible Role of Plasma Kallikrein in Pro-Hormone and Pro-Enzyme Processing (1988) (0)

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