Michel Goedert

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Michel Goedert is affiliated with the following schools: Duke University, University of Cambridge

Michel Goedert's AcademicInfluence.com Rankings

Michel Goedert

Biology

#2604

World Rank

#4110

Historical Rank

Neuroscience

#226

World Rank

#239

Historical Rank

Biochemistry

#218

World Rank

#273

Historical Rank

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Biology

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Michel Goedert's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

α-Synuclein in Lewy bodies (1997) (4852)
Alpha-synuclein in Lewy bodies. (1997) (2847)
α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson’s disease and dementia with Lewy bodies (1998) (2581)
Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease (1989) (2149)
Neurodegenerative tauopathies. (2001) (1834)
A Century of Alzheimer's Disease (2006) (1770)
Transmission and spreading of tauopathy in transgenic mouse brain (2009) (1529)
Mutation in the tau gene in familial multiple system tauopathy with presenile dementia. (1998) (1443)
Alpha-synuclein and neurodegenerative diseases (2001) (1257)
alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies. (1998) (1031)
Identification of two distinct synucleins from human brain (1994) (1025)
Tau proteins of alzheimer paired helical filaments: Abnormal phosphorylation of all six brain isoforms (1992) (1007)
Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau. (1988) (994)
Cryo-EM structures of Tau filaments from Alzheimer’s disease brain (2017) (981)
Cloning and sequencing of the cDNA encoding an isoform of microtubule‐associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain. (1989) (958)
Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans (1996) (918)
100 years of Lewy pathology (2013) (899)
Tau pathology and neurodegeneration (2013) (849)
Expression of separate isoforms of human tau protein: correlation with the tau pattern in brain and effects on tubulin polymerization. (1990) (835)
Abnormal tau phosphorylation at Ser396 in alzheimer's disease recapitulates development and contributes to reduced microtubule binding (1993) (810)
Filamentous α-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies (1998) (802)
GSK3 inhibitors: development and therapeutic potential (2004) (738)
Fiber diffraction of synthetic alpha-synuclein filaments shows amyloid-like cross-beta conformation. (2000) (708)
Alzheimer’s and Parkinson’s diseases: The prion concept in relation to assembled Aβ, tau, and α-synuclein (2015) (684)
Tau protein pathology in neurodegenerative diseases (1998) (677)
Tau protein and the neurofibrillary pathology of Alzheimer's disease (1993) (650)
Brain homogenates from human tauopathies induce tau inclusions in mouse brain (2013) (618)
Abundant Tau Filaments and Nonapoptotic Neurodegeneration in Transgenic Mice Expressing Human P301S Tau Protein (2002) (615)
Binding of α-Synuclein to Brain Vesicles Is Abolished by Familial Parkinson’s Disease Mutation* (1998) (536)
Monoclonal antibody AT8 recognises tau protein phosphorylated at both serine 202 and threonine 205 (1995) (530)
Structures of filaments from Pick’s disease reveal a novel tau protein fold (2018) (489)
Inhibition of Heparin-induced Tau Filament Formation by Phenothiazines, Polyphenols, and Porphyrins* (2005) (485)
Tau proteins with FTDP‐17 mutations have a reduced ability to promote microtubule assembly (1998) (473)
Biophysical Properties of the Synucleins and Their Propensities to Fibrillate (2002) (463)
Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease. (1994) (458)
The switch of tau protein to an Alzheimer‐like state includes the phosphorylation of two serine‐proline motifs upstream of the microtubule binding region. (1992) (456)
Hypothesis: Microtubule Instability and Paired Helical Filament Formation in the Alzheimer Disease Brain Are Related to Apolipoprotein E Genotype (1994) (454)
Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform. (1995) (438)
The propagation of prion-like protein inclusions in neurodegenerative diseases (2010) (437)
The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development. (1993) (437)
Monoclonal antibody PHF‐1 recognizes tau protein phosphorylated at serine residues 396 and 404 (1994) (437)
High prevalence of mutations in the microtubule-associated protein tau in a population study of frontotemporal dementia in the Netherlands. (1999) (418)
Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies. (1998) (409)
Activation of stress‐activated protein kinase‐3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of SAPK3 and SAPK2 (RK/p38) (1997) (400)
The α‐Synucleinopathies: Parkinson's Disease, Dementia with Lewy Bodies, and Multiple System Atrophy (2000) (398)
Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules (2019) (397)
Frontotemporal dementia and corticobasal degeneration in a family with a P301S mutation in tau. (1999) (395)
Mutations causing neurodegenerative tauopathies. (2005) (389)
A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity (2014) (369)
The mas oncogene encodes an angiotensin receptor (1988) (368)
Synthetic filaments assembled from C‐terminally truncated α‐synuclein (1998) (354)
Propagation of Tau Aggregates and Neurodegeneration. (2017) (351)
Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: identification of phosphorylation sites in tau protein. (1994) (349)
Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein (2000) (346)
Detection of Phosphorylated Ser262 in Fetal Tau, Adult Tau, and Paired Helical Filament Tau (*) (1995) (334)
Dose-dependent effects of capsaicin on primary sensory neurons in the neonatal rat (1983) (330)
Invited review: Frontotemporal dementia caused by microtubule-associated protein tau gene (MAPT) mutations: a chameleon for neuropathology and neuroimaging (2015) (329)
Nerve growth factor mRNA in peripheral and central rat tissues and in the human central nervous system: lesion effects in the rat brain and levels in Alzheimer's disease. (1986) (327)
Familial multiple system tauopathy with presenile dementia: a disease with abundant neuronal and glial tau filaments. (1997) (325)
Repeat motifs of tau bind to the insides of microtubules in the absence of taxol (2003) (317)
Proteasomal degradation of tau protein (2002) (316)
Structures of α-synuclein filaments from multiple system atrophy (2020) (312)
The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bepsilon at Ser539 and the microtubule-associated protein tau at Thr212: potential role for DYRK as a glycogen synthase kinase 3-priming kinase. (2001) (307)
The Synucleinopathies: Twenty Years On (2017) (307)
Pathological Changes in Dopaminergic Nerve Cells of the Substantia Nigra and Olfactory Bulb in Mice Transgenic for Truncated Human α-Synuclein(1–120): Implications for Lewy Body Disorders (2006) (303)
Molecular characterization of microtubule-associated proteins tau and map2 (1991) (300)
Phosphorylation of microtubule‐associated protein tau by stress‐activated protein kinases (1997) (298)
Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution. (1998) (297)
Stimulation of autophagy reduces neurodegeneration in a mouse model of human tauopathy (2012) (293)
Tau filaments from human brain and from in vitro assembly of recombinant protein show cross-β structure (2003) (274)
Fatal attractions: abnormal protein aggregation and neuron death in Parkinson's disease and Lewy body dementia (1998) (274)
Novel tau filament fold in corticobasal degeneration (2020) (268)
Filamentous nerve cell inclusions in neurodegenerative diseases (1998) (267)
Vascular variant of prion protein cerebral amyloidosis with tau-positive neurofibrillary tangles: the phenotype of the stop codon 145 mutation in PRNP. (1996) (267)
Nerve growth factor counteracts the neurophysiological and neurochemical effects of chronic sciatic nerve section (1985) (266)
p42 map kinase phosphorylation sites in microtubule‐associated protein tau are dephosphorylated by protein phosphatase 2A1 Implications for Alzheimer's disease (1992) (264)
Tau Mutations Cause Frontotemporal Dementias (1998) (264)
A GSK3‐binding peptide from FRAT1 selectively inhibits the GSK3‐catalysed phosphorylation of Axin and β‐catenin (1999) (256)
Effects of frontotemporal dementia FTDP‐17 mutations on heparin‐induced assembly of tau filaments (1999) (255)
SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson's disease. (2010) (251)
Paradoxical activation of Raf by a novel Raf inhibitor. (1999) (250)
PART is part of Alzheimer disease (2015) (243)
p38γ regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP (2005) (243)
Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17. (1999) (240)
Mutation E46K increases phospholipid binding and assembly into filaments of human α‐synuclein (2004) (240)
Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer’s and Pick’s diseases (2018) (235)
Tau gene mutation G389R causes a tauopathy with abundant pick body-like inclusions and axonal deposits. (1999) (224)
Cloning of a big tau microtubule-associated protein characteristic of the peripheral nervous system. (1992) (222)
What is the evidence that tau pathology spreads through prion-like propagation? (2017) (221)
The alpha-synucleinopathies: Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy. (2000) (218)
Glycogen synthase kinase-3β phosphorylates tau protein at multiple sites in intact cells (1995) (215)
Like prions: the propagation of aggregated tau and &agr;-synuclein in neurodegeneration (2017) (214)
A panel of epitope‐specific antibodies detects protein domains distributed throughout human α‐synuclein in lewy bodies of Parkinson's disease (2000) (212)
Synergistic activation of SAPK1/JNK1 by two MAP kinase kinases in vitro (1998) (212)
Conformation Determines the Seeding Potencies of Native and Recombinant Tau Aggregates (2014) (211)
Neuronal localization of amyloid beta protein precursor mRNA in normal human brain and in Alzheimer's disease. (1987) (209)
A Raman optical activity study of rheomorphism in caseins, synucleins and tau. New insight into the structure and behaviour of natively unfolded proteins. (2002) (207)
Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7. (2000) (207)
FTDP‐17 mutations N279K and S305N in tau produce increased splicing of exon 10 (1999) (205)
Alzheimer-like Changes in Microtubule-associated Protein Tau Induced by Sulfated Glycosaminoglycans (1997) (199)
The Alzheimer‐like phosphorylation of tau protein reduces microtubule binding and involves Ser‐Pro and Thr‐Pro motifs (1992) (199)
Rodent models for Alzheimer disease (2018) (195)
Structure-based classification of tauopathies (2021) (194)
Requirement of nerve growth factor for development of substance P-containing sensory neurones (1980) (194)
Rapamycin Attenuates the Progression of Tau Pathology in P301S Tau Transgenic Mice (2013) (192)
Induction of inflammatory mediators and microglial activation in mice transgenic for mutant human P301S tau protein. (2004) (191)
Tau pathology in a family with dementia and a P301L mutation in tau. (1999) (187)
Tau gene mutation in familial progressive subcortical gliosis (1999) (184)
Biological importance of the retrograde axonal transport of nerve growth factor in sensory neurons. (1981) (184)
Tau Proteins and Neurofibrillary Degeneration (1991) (181)
Tau filaments from multiple cases of sporadic and inherited Alzheimer’s disease adopt a common fold (2018) (181)
Interaction of tau protein with the dynactin complex (2007) (178)
Abnormal tau-containing filaments in neurodegenerative diseases. (2000) (177)
The Regional Distribution and Chromatographic Characterisation of Neurotensin‐Like Immunoreactivity in the Rat Central Nervous System (1982) (175)
Tau protein, the paired helical filament and Alzheimer's disease. (2006) (172)
SAP kinase‐3, a new member of the family of mammalian stress‐activated protein kinases (1996) (171)
Filamentous nerve cell inclusions in neurodegenerative diseases: tauopathies and alpha-synucleinopathies. (1999) (168)
Tau protein and neurodegeneration. (2004) (168)
Pick’s disease: hyperphosphorylated tau protein segregates to the somatoaxonal compartment (1996) (167)
Tau Gene Mutation K257T Causes a Tauopathy Similar to Pick's Disease (2000) (166)
Characterization of mAb AP422, a novel phosphorylation‐dependent monoclonal antibody against tau protein (1996) (165)
Why has therapy development for dementia failed in the last two decades? (2016) (165)
Stress-activated protein kinase-3 interacts with the PDZ domain of alpha1-syntrophin. A mechanism for specific substrate recognition. (1999) (164)
Phosphorylation of microtubule‐associated protein tau by isoforms of c‐Jun N‐terminal kinase (JNK) (2004) (163)
Comparison of the neurofibrillary pathology in Alzheimer’s disease and familial presenile dementia with tangles (1996) (161)
Correlation between inositol phospholipid hydrolysis and substance P receptors in rat CNS (1984) (160)
Synthetic filaments assembled from C-terminally truncated alpha-synuclein. (1998) (158)
Effect of SB 203580 on the activity of c-Raf in vitro and in vivo (1999) (157)
AD2, a phosphorylation-dependent monoclonal antibody directed against tau proteins found in Alzheimer's disease. (1996) (152)
The microtubule binding repeats of tau protein assemble into filaments like those found in Alzheimer's disease (1992) (149)
Assembly of Alzheimer‐like filaments from full‐length tau protein (1994) (149)
Protein Phosphatase 2A Is the Major Enzyme in Brain that Dephosphorylates τ Protein Phosphorylated by Proline‐Directed Protein Kinases or Cyclic AMP‐Dependent Protein Kinase (1995) (144)
A novel tau mutation (N296N) in familial dementia with swollen achromatic neurons and corticobasal inclusion bodies (2000) (144)
Mutation E46K increases phospholipid binding and assembly into filaments of human alpha-synuclein. (2004) (141)
Propagation of Tau aggregates (2017) (140)
Tau mutations in frontotemporal dementia FTDP-17 and their relevance for Alzheimer's disease. (2000) (138)
Long-Term In Vivo Imaging of Fibrillar Tau in the Retina of P301S Transgenic Mice (2012) (138)
Role of endogenous substance P in stress-induced activation of mesocortical dopamine neurones (1983) (137)
Nerve growth factor mRNA and protein increase in hypothalamus in a mouse model of aggression. (1989) (137)
Tau protein is phosphorylated by cyclic AMP-dependent protein kinase and calcium/calmodulin-dependent protein kinase II within its microtubule-binding domains at Ser-262 and Ser-356. (1996) (135)
Pick's disease associated with the novel Tau gene mutation K369I (2001) (135)
Invited review: Prion‐like transmission and spreading of tau pathology (2015) (135)
The nature of the substance P-containing nerve fibres in taste papillae of the rat tongue (1982) (132)
Tau gene mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) (2000) (132)
Frontotemporal dementia: implications for understanding Alzheimer disease. (2012) (130)
Characterisation of isolated α-synuclein filaments from substantia nigra of Parkinson's disease brain (2000) (130)
Evidence that phosphorylation of the microtubule-associated protein Tau by SAPK4/p38δ at Thr50 promotes microtubule assembly (2005) (129)
Fiber diffraction of synthetic a-synuclein filaments shows amyloid-like cross-b conformation (2000) (127)
“Prion‐Like” Templated Misfolding in Tauopathies (2013) (125)
Use of a drug‐resistant mutant of stress‐activated protein kinase 2a/p38 to validate the in vivo specificity of SB 203580 (1999) (123)
Nerve growth factor receptor mRNA distribution in human brain: normal levels in basal forebrain in Alzheimer's disease. (1989) (123)
Biochemical and anatomical effects of antibodies against nerve growth factor on developing rat sensory ganglia. (1984) (122)
Pathogenesis of the Tauopathies (2011) (119)
Peripheral administration of tau aggregates triggers intracerebral tauopathy in transgenic mice (2013) (118)
A novel mutation at position +12 in the intron following Exon 10 of the tau gene in familial frontotemporal dementia (FTD‐Kumamoto) (2000) (116)
Analysis of tau phosphorylation and truncation in a mouse model of human tauopathy. (2008) (116)
A role for FKBP52 in Tau protein function (2010) (115)
Tau gene mutations and their effects (2005) (115)
Assignment of human alpha-synuclein (SNCA) and beta-synuclein (SNCB) genes to chromosomes 4q21 and 5q35. (1995) (113)
Short Fibrils Constitute the Major Species of Seed-Competent Tau in the Brains of Mice Transgenic for Human P301S Tau (2016) (112)
Cytosolic Fc receptor TRIM21 inhibits seeded tau aggregation (2017) (111)
Tau inclusions in retinal ganglion cells of human P301S tau transgenic mice: Effects on axonal viability (2011) (111)
Methylene blue and dimebon inhibit aggregation of TDP‐43 in cellular models (2009) (109)
Neurotensin stimulates inositol phospholipid hydrolysis in rat brain slices (1984) (109)
Tau: From research to clinical development (2016) (108)
Molecular structure of microtubule-associated protein 2b and 2c from rat brain. (1990) (108)
Prion-like Mechanisms in the Pathogenesis of Tauopathies and Synucleinopathies (2014) (108)
Specific binding of triatiated neurotensin to rat brain membranes: Characterization and regional distribution (1984) (106)
Cryo-EM structures of tau filaments. (2020) (106)
PTL-1, a microtubule-associated protein with tau-like repeats from the nematode Caenorhabditis elegans. (1996) (105)
White Matter Tauopathy With Globular Glial Inclusions: A Distinct Sporadic Frontotemporal Lobar Degeneration (2008) (105)
Regulation of Alternative Splicing of Human Tau Exon 10 by Phosphorylation of Splicing Factors (2001) (104)
Neurofibrillary tangles and β-amyloid deposits in Alzheimer's disease (1991) (103)
Argyrophilic grain disease: widespread hyperphosphorylation of tau protein in limbic neurons (1997) (102)
Expression of APP in transgenic mice: a Comparison of neuron-specific promoters (1996) (102)
Oskar Fischer and the study of dementia (2008) (101)
P4-261 Small molecule inhibitors of alpha-synuclein filament assembly (2006) (99)
Epitope mapping of LB509, a monoclonal antibody directed against human α-synuclein (1999) (99)
Living Neurons with Tau Filaments Aberrantly Expose Phosphatidylserine and Are Phagocytosed by Microglia (2018) (97)
Cryo-EM structures of amyloid-β 42 filaments from human brains (2022) (97)
Cell-Mediated Neuroprotection in a Mouse Model of Human Tauopathy (2010) (97)
Reduced Binding of Protein Phosphatase 2A to Tau Protein with Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17 Mutations (2000) (95)
Biochemical effects of antibodies against nerve growth factor on developing and differentiated sympathetic ganglia (1978) (95)
A simple algorithm locates β‐strands in the amyloid fibril core of α‐synuclein, Aβ, and tau using the amino acid sequence alone (2007) (94)
Stress- and mitogen-induced phosphorylation of the synapse-associated protein SAP90/PSD-95 by activation of SAPK3/p38gamma and ERK1/ERK2. (2004) (92)
Lewy body diseases and multiple system atrophy as α-synucleinopathies (1998) (91)
In vitro high affinity α-synuclein binding sites for the amyloid imaging agent PIB are not matched by binding to Lewy bodies in postmortem human brain1 (2008) (89)
Tau Protein and the Neurofibrillary Pathology of Alzheimer's Disease (1996) (89)
Familial Parkinson's disease: The awakening of α-synuclein (1997) (89)
The repeat region of microtubule-associated protein tau forms part of the core of the paired helical filament of Alzheimer's disease. (1989) (88)
A novel tau mutation, S320F, causes a tauopathy with inclusions similar to those in Pick's disease (2002) (87)
The Structural Basis for Optimal Performance of Oligothiophene-Based Fluorescent Amyloid Ligands: Conformational Flexibility is Essential for Spectral Assignment of a Diversity of Protein Aggregates (2013) (87)
Parkinsons Disease and other α-Synucleinopathies (2001) (86)
The Neurofibrillary Pathology of Alzheimer's Disease (1997) (86)
Localization of the Alz-50 epitope in recombinant human microtubule-associated protein tau (1991) (86)
Circadian clocks and neurodegenerative diseases: time to aggregate?☆ (2013) (86)
Variable phenotypic expression and extensive tau pathology in two families with the novel tau mutation L315R (2003) (85)
Molecular dissection of the paired helical filament (1995) (85)
The tauopathy associated with mutation +3 in intron 10 of Tau: characterization of the MSTD family (2007) (84)
The value of incomplete mouse models of Alzheimer’s disease (2008) (83)
Isoform-specific interactions of apolipoprotein E with the microtubule-associated protein MAP2c: implications for Alzheimer's disease (1994) (83)
Parkinson’s Disease – the Debate on the Clinical Phenomenology, Aetiology, Pathology and Pathogenesis (2014) (83)
Casein kinase 2 is the major enzyme in brain that phosphorylates Ser129 of human α‐synuclein: Implication for α‐synucleinopathies (2007) (82)
Familial multiple-system tauopathy with presenile dementia is localized to chromosome 17. (1997) (81)
Two‐Dimensional Characterization of Paired Helical Filament‐Tau from Alzheimer's Disease: Demonstration of an Additional 74‐kDa Component and Age‐Related Biochemical Modifications (1997) (81)
Stimulation of autophagy is neuroprotective in a mouse model of human tauopathy (2012) (80)
Tau filaments in neurodegenerative diseases (2018) (79)
Structural basis for recognition of the RNA major groove in the tau exon 10 splicing regulatory element by aminoglycoside antibiotics. (2000) (78)
The significance of tau and α-synuclein inclusions in neurodegenerative diseases (2001) (78)
Tau Proteins Are Abnormally Expressed in Olfactory Epithelium of Alzheimer Patients and Developmentally Regulated in Human Fetal Spinal Cord (1993) (78)
Neurofibrillary pathology of Alzheimer's disease and other tauopathies. (1998) (77)
Endogenous opioid peptides. (1981) (77)
Tau Gene Mutations in Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17 (FTDP‐17): Their Relevance for Understanding the Neurogenerative Process (2000) (75)
Early behavioural markers of disease in P301S tau transgenic mice (2010) (75)
Phosphorylation of cytosolic phospholipase A2 in platelets is mediated by multiple stress-activated protein kinase pathways. (1999) (75)
Anti-amyloid Compounds Inhibit α-Synuclein Aggregation Induced by Protein Misfolding Cyclic Amplification (PMCA)* (2014) (74)
Phosphorylation of microtubule‐associated protein tau by stress‐activated protein kinases in intact cells (2002) (72)
Microtubule-associated protein tau, heparan sulphate and α-synuclein in several neurodegenerative diseases with dementia (1999) (71)
Galectin-8–mediated selective autophagy protects against seeded tau aggregation (2017) (71)
α-synuclein adopts an α-helical conformation in the presence of polyunsaturated fatty acids to hinder micelle formation (2006) (70)
Cathepsin D displays in vitro β-secretase-like specificity (1997) (70)
Inverse relationship between neurotensin receptors and neurotensin-like immunoreactivity in cat striatum (1984) (70)
Mosaic distribution of neurotensin-like immunoreactivity in the cat striatum (1983) (69)
Neurotensin receptors in the rat striatum: lesion studies (1984) (69)
Synaptotagmin V: a novel synaptotagmin isoform expressed in rat brain (1995) (69)
Neurodegeneration and the ordered assembly of α-synuclein (2017) (67)
Protein phosphatase 2A is the major enzyme in brain that dephosphorylates tau protein phosphorylated by proline-directed protein kinases or cyclic AMP-dependent protein kinase. (1995) (67)
Sequential phosphorylation of tau protein by cAMP‐dependent protein kinase and SAPK4/p38δ or JNK2 in the presence of heparin generates the AT100 epitope (2006) (66)
Cysteine misincorporation in bacterially expressed human α‐synuclein (2006) (66)
Neurotensin in the rat anterior pituitary gland (1982) (65)
The regional distribution of neurotensin-like immunoreactivity in central and peripheral tissues of the cat (1983) (65)
Immunization of adult rats against 2.5 S NGF: Effects on the peripheral sympathetic nervous system (1979) (64)
From genetics to pathology: tau and alpha-synuclein assemblies in neurodegenerative diseases. (2001) (62)
Cryo-EM structures of tau filaments from Alzheimer’s disease with PET ligand APN-1607 (2021) (61)
Topographical relationship between beta-amyloid and tau protein epitopes in tangle-bearing cells in Alzheimer disease. (1990) (60)
Reduced Axonal Transport and Increased Excitotoxic Retinal Ganglion Cell Degeneration in Mice Transgenic for Human Mutant P301S Tau (2012) (60)
Phosphorylation of microtubule‐associated protein tau by AMPK‐related kinases (2012) (60)
Modeling familial Danish dementia in mice supports the concept of the amyloid hypothesis of Alzheimer's disease (2010) (59)
Different configurational states of beta-amyloid and their distributions relative to plaques and tangles in Alzheimer disease. (1990) (59)
Sequence Determinants for Amyloid Fibrillogenesis of Human α-Synuclein (2007) (59)
Measurement of Tau Filament Fragmentation Provides Insights into Prion-like Spreading. (2018) (59)
Tau mutations in familial frontotemporal dementia. (2000) (59)
Evidence for neurotensin as a non-adrenergic, non-cholinergic neurotransmitter in guinea pig ileum (1984) (59)
The origin of substance P in the rat submandibular gland and its major duct (1982) (58)
Morphological, Biochemical, and Genetic Support for an Apolipoprotein E Effect on Microtubular Metabolism a (1996) (57)
Tau gene mutations and neurodegeneration. (2001) (56)
Abundant neuritic inclusions and microvacuolar changes in a case of diffuse Lewy body disease with the A53T mutation in the α-synuclein gene (2005) (56)
Tau gene (MAPT) sequence variation among primates. (2004) (56)
SKK4, a novel activator of stress‐activated protein kinase‐1 (SAPK1/JNK) (1997) (55)
Risky apolipoprotein in brain (1994) (54)
Lewy body diseases and multiple system atrophy as alpha-synucleinopathies. (1998) (53)
Functional Characterization of FTDP-17 tau Gene Mutations through Their Effects on Xenopus Oocyte Maturation* (2002) (52)
Parkinson's disease and other alpha-synucleinopathies. (2001) (52)
The possible relation of glutathione, melanin and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) to Parkinson's disease. (1984) (52)
ApoE3 binding to tau tandem repeat I is abolished by tau serine262 phosphorylation (1995) (52)
Tau-Driven Neuronal and Neurotrophic Dysfunction in a Mouse Model of Early Tauopathy (2016) (50)
Characterisation of isolated alpha-synuclein filaments from substantia nigra of Parkinson's disease brain. (2000) (49)
Distribution of β‐nerve growth factor receptors in the human basal forebrain (1989) (48)
Inhibition of α‐synuclein fibril assembly by small molecules: Analysis using epitope‐specific antibodies (2009) (48)
Impaired plasticity of cortical dendritic spines in P301S tau transgenic mice (2013) (47)
Molecular cloning and functional characterization of chicken brain tau: isoforms with up to five tandem repeats. (2002) (47)
The ordered assembly of tau is the gain-of-toxic function that causes human tauopathies (2016) (47)
Mammalian tachykinin-induced hydrolysis of inositol phospholipids in rat brain slices. (1985) (45)
Detection of filamentous tau inclusions by the fluorescent Congo red derivative FSB [(trans,trans)-1-fluoro-2,5-bis(3-hydroxycarbonyl-4-hydroxy)styrylbenzene] (2008) (45)
Cathepsin D displays in vitro beta-secretase-like specificity. (1997) (45)
Seeded assembly in vitro does not replicate the structures of α‐synuclein filaments from multiple system atrophy (2021) (45)
Neurotensin in the adrenal medulla (1983) (44)
Molecular dissection of the neurofibrillary lesions of Alzheimer's disease. (1995) (44)
Alternative splicing of synaptotagmins involving transmembrane exon skipping (1999) (44)
Expression and cellular localization of amyloid β-protein precursor transcripts in normal human brain and in Alzheimer's disease (1989) (44)
Epitope mapping of LB509, a monoclonal antibody directed against human alpha-synuclein. (1999) (43)
Seeded assembly in vitro does not replicate the structures of α-synuclein filaments from multiple system atrophy (2020) (43)
Engineered antibodies: new possibilities for brain PET? (2019) (42)
Alois Alzheimer: His Life and Times (2007) (41)
Assembly of recombinant tau into filaments identical to those of Alzheimer’s disease and chronic traumatic encephalopathy (2021) (41)
A simple algorithm locates beta-strands in the amyloid fibril core of alpha-synuclein, Abeta, and tau using the amino acid sequence alone. (2007) (41)
Dopamine, norepinephrine and serotonin production by an intestinal carcinoid tumor (1980) (41)
The natural osmolyte trimethylamine N‐oxide (TMAO) restores the ability of mutant tau to promote microtubule assembly (2000) (41)
Co-expression of truncated and full-length tau induces severe neurotoxicity (2016) (40)
Examination of the role of endopeptidase 3.4.24.15 in Aβ secretion by human transfected cells (1997) (40)
Regenerating sciatic nerve axons contain the adult rather than the embryonic pattern of microtubule associated proteinS (1994) (40)
Tau silencing by siRNA in the P301S mouse model of tauopathy. (2014) (40)
Distinct Conformers of Assembled Tau in Alzheimer's and Pick's Diseases. (2019) (40)
Structures of α-synuclein filaments from human brains with Lewy pathology (2022) (39)
Tau protein in Alzheimer's disease. (1995) (39)
The Structure of Cross‐β Tapes and Tubes Formed by an Octapeptide, αSβ1† (2013) (39)
Neurotensin in human brain: Regional distribution and effects of neurological illness (1985) (39)
Cell-cycle markers in a transgenic mouse model of human tauopathy: increased levels of cyclin-dependent kinase inhibitors p21Cip1 and p27Kip1. (2006) (38)
Phosphorylation of tau by cyclic-AMP-dependent protein kinase. (1993) (38)
Casein kinase 2 is the major enzyme in brain that phosphorylates Ser129 of human alpha-synuclein: Implication for alpha-synucleinopathies. (2007) (37)
Axotrophin/MARCH7 acts as an E3 ubiquitin ligase and ubiquitinates tau protein in vitro impairing microtubule binding (2014) (37)
The tauopathies: toward an experimental animal model. (1999) (37)
Age-dependent formation of TMEM106B amyloid filaments in human brains (2021) (36)
Distinct Spacing Between Anionic Groups: An Essential Chemical Determinant for Achieving Thiophene-Based Ligands to Distinguish β-Amyloid or Tau Polymorphic Aggregates (2015) (36)
Ordered Assembly of Tau Protein and Neurodegeneration. (2019) (35)
Inhibition of synucleinopathic seeding by rationally designed inhibitors (2020) (35)
Neurofibrillary tangles and beta-amyloid deposits in Alzheimer's disease. (1991) (35)
The effects of chronic neuroleptic treatment on neurotensin-like immunoreactivity in the rat central nervous system (1985) (34)
Synucleinopathies: past, present and future (2016) (34)
Intraneuronal filamentous tau protein and α-synuclein deposits in neurodegenerative diseases (1998) (34)
The novel Tau mutation G335S: clinical, neuropathological and molecular characterization (2007) (33)
Progress in Hereditary Tauopathies: A Mutation in the Tau Gene (G389R) Causes a Pick Disease‐like Syndrome (2000) (33)
The novel MAPT mutation K298E: mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neurons (2013) (33)
Tau and Parkinson disease. (2001) (33)
Tau Pathology is Present In Vivo and Develops In Vitro in Sensory Neurons from Human P301S Tau Transgenic Mice: A System for Screening Drugs against Tauopathies (2013) (32)
Functional effects of tau gene mutations ΔN296 and N296H (2002) (32)
Functional effects of tau gene mutations deltaN296 and N296H. (2002) (32)
Neurotensin — a status report (1984) (31)
The fluorescent pentameric oligothiophene pFTAA identifies filamentous tau in live neurons cultured from adult P301S tau mice (2015) (31)
Effects of antibodies against nerve growth factor on the postnatal development of substance P-containing sensory neurons (1982) (31)
The significance of tau and alpha-synuclein inclusions in neurodegenerative diseases. (2001) (31)
Alpha-synuclein adopts an alpha-helical conformation in the presence of polyunsaturated fatty acids to hinder micelle formation. (2006) (30)
Early‐onset Dementia with Lewy Bodies (2004) (30)
Immunosympathectomy: Lack of evidence for a complement-mediated cytotoxic mechanism (1980) (29)
Human tau isoforms confer distinct morphological and functional properties to stably transfected fibroblasts. (1993) (29)
Amyloid plaques, neurofibrillary tangles and their relevance for the study of Alzheimer's disease (1989) (29)
The Transcellular Propagation and Intracellular Trafficking of α-Synuclein. (2017) (29)
Sequence Determinants for Amyloid Fibrillogenesis of Human alpha-Synuclein. (2007) (27)
Neurotensin in human small cell lung carcinoma. (1984) (27)
Luminescent conjugated oligothiophenes distinguish between α-synuclein assemblies of Parkinson’s disease and multiple system atrophy (2019) (27)
Parkinson's disease — the story of an eponym (2018) (26)
Neurotensin-like immunoreactivity and neurotensin receptors in the rat hypothalamus and in the neurointermediate lobe of the pituitary gland (1985) (26)
Tau Filaments and the Development of Positron Emission Tomography Tracers (2018) (26)
Cysteine misincorporation in bacterially expressed human alpha-synuclein. (2006) (26)
NEUROTENSIN: REGIONAL DISTRIBUTION, CHARACTERIZATION, AND INACTIVATION (1982) (26)
Frontotemporal lobar degeneration through loss of progranulin function. (2006) (25)
In Vivo Analysis of Wild‐type and FTDP‐17 Tau Transgenic Mice (2000) (25)
Silver staining (Campbell-Switzer) of neuronal α-synuclein assemblies induced by multiple system atrophy and Parkinson’s disease brain extracts in transgenic mice (2019) (25)
The Prion-Like Behavior of Assembled Tau in Transgenic Mice. (2017) (25)
Phosphorylation of human microtubule‐associated protein tau by protein kinases of the AGC subfamily (2007) (24)
Familial Parkinson's disease. The awakening of alpha-synuclein. (1997) (24)
Synuclein proteins of the pufferfish Fugu rubripes: sequences and functional characterization. (2006) (24)
The comparative distribution of xenopsin- and neurotensin-like immunoreactivity inxenopus laevis and rat tissues (1984) (23)
Beta amyloid resurrected (1991) (22)
Autoradiographic visualization of receptor binding sites for substance P in the gastrointestinal tract of the guinea pig. (1984) (22)
Neurotensin in the rat anterior pituitary gland: effects of endocrinological manipulations (1984) (22)
Novel tau filament fold in corticobasal degeneration, a four-repeat tauopathy (2019) (22)
Molecular cloning of the chicken nerve growth factor gene: mRNA distribution in developing and adult tissues. (1986) (22)
The cellular localization of preprotachykinin a messenger rna in the bovine nervous system (1987) (21)
Localization and actions of cholecystokinin in the rat pituitary neurointermediate lobe. (1984) (21)
Stress-activated Protein Kinase-3 Interacts with the PDZ Domain of α1-Syntrophin (1999) (21)
Ubiquitination of alpha-synuclein filaments by Nedd4 ligases (2018) (21)
Parkinson's Disease, Dementia with Lewy Bodies, and Multiple System Atrophy as α-Synucleinopathies. (2001) (20)
Tau protein and the paired helical filament of Alzheimer’s disease (1999) (20)
Intraneuronal filamentous tau protein and alpha-synuclein deposits in neurodegenerative diseases. (1998) (19)
Mutations in the tau gene (MAPT) in FTDP-17: the family with Multiple System Tauopathy with Presenile Dementia (MSTD). (2006) (19)
Long-Term In Vivo Imaging of Fibrillar Tau in the Retina of P 301 S Transgenic Mice (2012) (19)
Effect of heparin on phosphorylation site specificity of neuronal Cdc2‐like kinase (1998) (18)
α-Synuclein filaments from transgenic mouse and human synucleinopathy-containing brains are major seed-competent species (2020) (18)
The regional distribution and chromatographic characterization of neurotensin-like immunoreactivity in the rat. (1982) (18)
Beta-sheet assembly of Tau and neurodegeneration in Drosophila melanogaster (2018) (17)
Tau protein and Alzheimer's disease (1994) (17)
Human β-Synuclein Rendered Fibrillogenic by Designed Mutations (2010) (17)
Biochemical effects of nerve growth factor and its antibody on the vas defferens and the adrenal medulla (1978) (16)
a-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies (ubiquitinysarkosyl-insoluble filamentsyimmunoelectron microscopy) (1998) (16)
Alzheimer's disease: Pinning down phosphorylated tau (1999) (16)
THE AWAKENING OF ALPHA -SYNUCLEIN (1997) (15)
Activation of the novel MAP kinase homologue SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6). (1997) (15)
Piericidin A Aggravates Tau Pathology in P301S Transgenic Mice (2014) (15)
Assembly of transgenic human P301S Tau is necessary for neurodegeneration in murine spinal cord (2019) (14)
Localization of specific neurotensin binding sites in the rat adrenal gland (1984) (13)
Engineering protein kinases with distinct nucleotide specificities and inhibitor sensitivities by mutation of a single amino acid. (1998) (13)
Tau proteinopathies and the prion concept. (2020) (13)
Changes in substance P concentrations after protein synthesis inhibition provide an index of substance P utilization (1984) (13)
Alzheimer's disease. Risky apolipoprotein in brain. (1994) (12)
Tau gene mutations and tau pathology in frontotemporal dementia and parkinsonism linked to chromosome 17. (2001) (12)
A Brief History of Tau. (2015) (11)
REVIEW ARTICLE Like prions: the propagation of aggregated tau and a -synuclein in neurodegeneration (2017) (11)
The mas oncogene as a neural peptide receptor: expression, regulation and mechanism of action. (1990) (11)
Classification of diseases with accumulation of Tau protein (2022) (11)
Radioligand-binding assays for study of neurotensin receptors. (1989) (10)
Human Tau Transgenic Mice (2001) (10)
Introduction to the Tauopathies (2011) (10)
Cerebrospinal fluid from Alzheimer’s disease patients promotes tau aggregation in transgenic mice (2019) (10)
Assignment of the human stress-activated protein kinase-3 gene (SAPK3) to chromosome 22q13.3 by fluorescence in situ hybridization. (1997) (10)
[Induction and spreading of tau pathology in a mouse model of Alzheimer's disease]. (2010) (10)
Neuropathological changes and cognitive deficits in rats transgenic for human mutant tau recapitulate human tauopathy (2019) (10)
Use of a heat-stable microtubule-associated protein class-specific antibody to investigate the mechanism of microtubule binding. (1991) (10)
Construction and characterization of a yeast artificial chromosome library containing 1.5 equivalents of human chromosome 21. (1992) (10)
Stimulation of the pituitary-adrenocortical axis and induction of tyrosine hydroxylase by nerve growth factor are not dependent on mouse submaxillary gland isorenin (1981) (9)
Human tau transgenic mice. Towards an animal model for neuro- and glialfibrillary lesion formation. (2001) (9)
Localization of the human kinesin light chain gene (KNS2) to chromosome 14q32.3 by fluorescence in situ hybridization. (1996) (9)
Tauopathies and α-Synucleinopathies (2000) (8)
Synucleinopathies and Tauopathies (2012) (8)
The ontogenetic development of neurotensin-like immunoreactivity and neurotensin receptors in the cat striatum. (1985) (8)
Human synaptotagmin V (SYT5): sequence, genomic structure, and chromosomal location. (1997) (8)
Neurodegenerative tauopathy in the worm (2003) (8)
Neurotensin in human small cell lung carcinoma. (1985) (7)
Synthesis and Assessment of Novel Probes for Imaging Tau Pathology in Transgenic Mouse and Rat Models (2021) (6)
Molecular neuropathology of Alzheimer's disease:In situ hybridization studies (1990) (6)
Parkinson's disease: Crystals of a toxic core (2015) (6)
Familial Alzheimer's disease. Beta amyloid resurrected. (1991) (6)
The comparative distribution of [Lys8-Asn9]-neurotensin8–13-like immunoreactivity in chicken and rat tissues (1985) (5)
Role of Nerve Growth Factor for the Development and Maintenance of Function of Sympathetic Neurons and Adrenal Medullary Cells1 (1978) (5)
Tau Protein and Frontotemporal Dementias. (2021) (5)
Characterisation of an Antibody Relevant to the Neuropathology of Alzheimer Disease (1995) (5)
Distribution of beta-nerve growth factor receptors in the human basal forebrain. (1989) (5)
Abundant Aβ fibrils in ultracentrifugal supernatants of aqueous extracts from Alzheimer’s disease brains (2022) (4)
The Cellular Localization of Preprotachykinin, Preproenkephalin A and Beta Prepronerve Growth Factor mRNA (1986) (4)
Assembly of α-synuclein and neurodegeneration in the central nervous system of heterozygous M83 mice following the peripheral administration of α-synuclein seeds (2021) (4)
The Alzheimer tangle — 100 years on. (2006) (4)
Cryo-EM structures of τ filaments from human brain (2021) (4)
Expression and cellular localization of amyloid beta-protein precursor transcripts in normal human brain and in Alzheimer's disease. (1989) (3)
Prion-like properties of assembled tau protein (2011) (3)
An extra sequence in the lambda EMBL3 polylinker. (1988) (3)
Cryo-EM Structures of Amyloid-β 42 Filaments from Human Brain (2021) (3)
Cryo-EM structures of amyloid-β filaments with the Arctic mutation (E22G) from human and mouse brains (2022) (3)
Cryo-EM structures of α-synuclein filaments from Parkinson’s disease and dementia with Lewy bodies (2022) (3)
THE ABNORMAL PHOSPHORYLATION OF TAU AT SER396 IN ALZHEIMERʼS DISEASE RECAPITULATES PHOSPHORYLATION DURING DEVELOPMENT AND CONTRIBUTES TO REDUCED MICROTUBULE BINDING (1993) (3)
Tau protein pathology in neurodegenerative (1998) (3)
AGGREGATE-SELECTIVE ANTI-TAU ANTIBODY MC-1 DEMONSTRATED ROBUST IN VITRO AND IN VIVO ACTIVITY TO NEUTRALIZE TRANSMISSIBLE TAU AND REDUCE TAU PATHOLOGY (2017) (3)
Dextran sulphate-induced tau assemblies cause endogenous tau aggregation and propagation in wild-type mice (2020) (3)
Apolipoprotein E and Alzheimer’s Disease: Therapeutic Implications (1994) (2)
Cyclic AMP-dependent protein kinase induces a shift in the electrophoretic mobility of human tau (1992) (2)
Relevance of Mutations in Tau for Understanding the Tauopathies (2003) (2)
Tracking tau fibrillogenesis and consequent primary phagocytosis of neurons mediated by microglia in a living tauopathy model (2020) (2)
Apolipoprotein E-e4 and apolipoprotein E-e2 are susceptibility genes that affect the rate of disease expressivity of late-onset familial and sporadic Alzheimer disease (1994) (2)
Neurodegeneration and the Ordered Assembly of Tau (2018) (2)
BIOCHEMICAL AND ANATOMICAL EFFECTS OF ANTIBODIES AGAINST NERVE GROWTH-FACTOR ON DEVELOPING RAT DORSAL ROOT-GANGLIA (1983) (2)
HEREDITARY MULTIPLE SYSTEM DEGENERATION WITH PRESENILE DEMENTIA: TAU (τ) ABNORMALITIES IN NERVE CELLS AND OLIGODENDROGLIA (1996) (2)
From genetics to pathology: tau and α-synuclein assemblies in neurodegenerative diseases - Discussion (2001) (2)
NEUROTENSIN IN THE PITUITARY GLAND (1982) (2)
WHITE CELLS AND URIC ACID IN ALCOHOLISM (1975) (2)
Erratum: Inverse relationship between neurotensin receptors and neurotensin-like immunoreactivity in cat striatum (1984) (2)
P1-086 Hyperphosphorylated tau accumulates in retinal ganglion neurons of P301S tau transgenic mice (2006) (1)
What is the evidence that tau pathology spreads through prion-like propagation? (2017) (1)
NMR STRUCTURE OF TAU EXON 10 SPLICING REGULATORY ELEMENT RNA (1999) (1)
Impaired plasticity of cortical dendritic spines in P301S tau transgenic mice (2013) (1)
Parkinson’s Disease: Alpha-Synuclein and Neurodegeneration (2009) (1)
Synthetic ¢laments assembled from C-terminally truncated K-synuclein (1998) (1)
Neurodegenerative α-Synucleinopathies (2005) (1)
Identical tau filaments in subacute sclerosing panencephalitis and chronic traumatic encephalopathy (2023) (1)
Protein Aggregation and Neurodegeneration: Tauopathies and Synucleinopathies (2017) (1)
Novel Cathepsin D Inhibitors Prevent the β-Secretase-Derived Intracellular Formation of a 12 kDa Potentially Amyloidogenic Product in Human Cells (1997) (1)
Increase in Tau Pathology in P290S Mapt Knock-In Mice Crossed with AppNL-G-F Mice (2022) (1)
A tribute to John Q. Trojanowski (1946–2022), neuropathologist extraordinaire (2022) (1)
In vivo analysis of wild-type and FTDP-17 tau mutant mice (2000) (1)
P1-076: Modeling Familial Danish dementia (2008) (1)
Receptors for Nonopioid Neuropeptides (1986) (1)
A cell-based model of pathological tau uptake and propagation (2013) (1)
Luminescent conjugated oligothiophenes distinguish between α-synuclein assemblies of Parkinson’s disease and multiple system atrophy (2019) (1)
322 Inhibitors of cathepsin D block β-secretase-like cleavage in human cells (1996) (1)
Commentary The Tauopathies Toward an Experimental Animal Model (1998) (1)
Prion-like properties of tau (2011) (0)
REGULATED RELEASE OF HYPER-PHOSPHORYLATED, AGGREGATED AND SEEDING COMPETENT TAU FROM RODENT BRAINS AND HUMAN SYNAPTOSOMES (2017) (0)
Editorial overview: Neurobiology of disease (2020) (0)
Table of Contents (1989) (0)
Silver staining (Campbell-Switzer) of neuronal α-synuclein assemblies induced by multiple system atrophy and Parkinson’s disease brain extracts in transgenic mice (2019) (0)
Neuronal localization of amyloid beta precursor mRNA in normal human brain and in Alzheimerʼs disease (1988) (0)
Nerve growth factor mRNA and protein increase in hypothalamus in a mouse model of aggression ( trophic interactions / gene transcription / in situ hybridization ) (0)
Chronic inhibition of the MEK/ERK pathway fails to delay disease progression in a transgenic animal model of tauopathy (2012) (0)
A cell-based model of pathological tau uptake and propagation (2013) (0)
AND ARE PHAGOCYTOSED LIVE BY MICROGLIA (0)
Molecular biology of chemical neurotransmission (1988) (0)
Multiple system atrophy Type I alpha-synuclein filament (2020) (0)
erratum: Shifting seas in the greenhouse? (1999) (0)
Globular glial tauopathy type 2 tau filament (2021) (0)
Paired helical filament from Alzheimer's disease with PET ligand APN-1607 (2021) (0)
100 and 50 years ago (1997) (0)
Paired helical filament from primary age-related tauopathy brain (2021) (0)
The Schmitt symposium: The cytoskeleton and Alzheimer's disease an introduction (1995) (0)
Tau mutations in FTDP-17 and their relevance for Alzheimer's disease (2000) (0)
Contents Vol.19, 2019 (2020) (0)
Tau Filaments from Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex (ALS/PDC) adopt the CTE Fold (2023) (0)
["Agrobacterium tumefaciens" (Smith and Town) Conn.: minimal inhibitory concentrations of various antibiotics and sulphonamide (author's transl)]. (1973) (0)
THE CELLULAR-LOCALIZATION OF MESSENGER-RNA IN NEUROBIOLOGY (1987) (0)
Characterization of a seed-competent tau species in a cell-based model of tauopathy (2013) (0)
Neurotrophin signaling is altered in the retina of the P301S mutant human tau transgenic mouse (2013) (0)
Novel tau filament fold in corticobasal degeneration (2020) (0)
CHARACTERISATION OF A CO-CULTURE CELL-BASED MODEL OF TAU AGGREGATION AND PROPAGATION (2014) (0)
Argyrophilic grain disease type 2 tau filament (2021) (0)
Conformation 2 of straight filament from primary age-related tauopathy brain (2021) (0)
CHARACTERISATION OF TAU SPECIES INVOLVED IN TAU SEEDING AND SPREAD IN CELLULAR AND ANIMAL MODELS (2016) (0)
Straight filament from Alzheimer's disease with PET ligand APN-1607 (2021) (0)
Cyclic Amplification ( PMCA )-Synuclein Aggregation Induced by Protein α Anti-amyloid Compounds Inhibit Neurobiology : (2014) (0)
Structures of α-synuclein filaments from multiple system atrophy (2020) (0)
New SNCA mutation and structures of α-synuclein filaments from juvenile-onset synucleinopathy (2022) (0)
Limbic-predominant neuronal inclusion body 4R tauopathy type 1a tau filament (2021) (0)
Paired helical filament from sporadic Alzheimer's disease brain (2018) (0)
Nerve growth factor: its growing importance for neurobiology and medicine. (1978) (0)
Nervegrowthfactor mRNA andprotein increase inhypothalamus inamousemodelofaggression (1989) (0)
TAU Assembly and propagation of pathology (2017) (0)
Screening of agents for the treatment of Alzheimer's disease (1997) (0)
Argyrophilic grain disease type 1 tau filament (2021) (0)
The hyperphosphorylation of tau and Alzheimer's disease (2010) (0)
Chronic traumatic encephalopathy Type I Tau filament (2019) (0)
404 Molecular characterization of the epitopes of two anti PHF-Tau monoclonal antibodies used in an immunoassay for the mapping of neurofibrillary degeneration in Alzheimer's disease (1996) (0)
Review Article Tau: From research to clinical development (2016) (0)
Topographical relationship between f 8-amyloid and tau protein epitopes in tangle-bearing cells in Alzheimer disease ( molecular pathology / amyloid fibrils / paired helical filaments ) (0)
Role of Nerve Growth Factor in the Function of Sympathetic Neurons and Adrenal Medullary Cells (1978) (0)
Assembly of transgenic human P301S Tau is necessary for neurodegeneration in murine spinal cord (2019) (0)
IDENTIFICATION OF TAU SPECIES REQUIRED FOR SEEDING IN A CELL-BASED MODEL OF PATHOLOGICAL TAU PROPAGATION (2014) (0)
Modeling familial danish dementia: Implications for the amyloid hypothesis of Alzheimer's disease (2010) (0)
Conformation 1 of straight filament from primary age-related tauopathy brain (2021) (0)
A love letter to the British people [1] (2016) (0)
TRANSMISSION AND SPREADING OF TAUOPATHIES IN TRANSGENIC MOUSE BRAIN (2014) (0)
α-Synuclein and Neurodegeneration (2004) (0)
Cryo-EM structure of TypeI tau filaments extracted from the brains of individuals with Corticobasal degeneration (2020) (0)
Progressive supranuclear palsy tau filament (2021) (0)
Cryo-EM structure of heparin-induced 2N3R tau filaments (2019) (0)
Cytosolic antibody receptor TRIM21 is required for effective tau immunotherapy in mouse models (2023) (0)
Narrow Pick Filament from Pick's disease brain (2018) (0)
Alterations of neurotrophin signaling in the retina of the P301S mutant human tau transgenic mouse (2013) (0)
24 th Annual Meeting of The Network of European CNS Transplantation and Restoration (2014) (0)
P1-084 Use of YFP imaging to study axon pathology in animal models of Alzheimer’s disease (2006) (0)
Tauopathy-induced retinal dysfunction in the P301S mutant human tau transgenic mouse (2013) (0)
Long-term in vivo imaging of tau pathology in the retina (2012) (0)
Nerve-growth-factor antibodies in idiopathic orthostatic hypotension? (1977) (0)
Procedes et compositions pour le diagnostic des pathologies tau (1999) (0)
Correction to: Cryo-EM structures of tau filaments from Alzheimer’s disease with PET ligand APN-1607 (2021) (0)
The cellular localization of mRNA in neurobiology. (1987) (0)
Molecular dissection of the neurofibrillary lesions of Alzheimer's disease. (1995) (0)
Verwendunf of ApoE for binding TAU and MAP2c proteins and for the treatment of Alzheimer's disease (1994) (0)
638 Characterization of tau-positive fibrillary pathology in familial multiple system degeneration with presenile dementia (1996) (0)
403 Characterization of mAb AP422, a novel phosphorylation-dependent monoclonal antibody against Tau protein (1996) (0)
Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules (2019) (0)
Multiple system atrophy Type II-2 alpha-synuclein filament (2020) (0)
Isoforms of the microtubule-associa ted protein tau: distribution in control and Alzheimer's disease brains (1990) (0)
A Conversation with Michel Goedert. (2019) (0)
A tribute to John Q. Trojanowski (1946-2022), neuropathologist extraordinaire. (2022) (0)
Chronic traumatic encephalopathy Type II Tau filament (2019) (0)
Tau mutations altering splicing of tau exon 10 in japanese frontotemporal dementia (2001) (0)
IN VITRO MEASUREMENTS OF TAU AGGREGATE ELONGATION AND FRAGMENTATION RATES ALLOW THE MODELLING OF PRION-LIKE SPREADING IN HUMANS (2018) (0)
Screening of active ingredients for treatment of alzheimer's disease (1997) (0)
Progressive tauopathy in P301S tau transgenic mice is associated with a functional deficit of the olfactory system (2011) (0)
Prions and the like (2013) (0)
Cryo-EM structures of tau filaments from SH-SY5Y cells seeded with brain extracts from cases of Alzheimer’s disease and corticobasal degeneration (2023) (0)
Cerebrospinal fluid from Alzheimer’s disease patients promotes tau aggregation in transgenic mice (2019) (0)
Why publish single observations? Because Science Matters. (2016) (0)
Disorders of Brain and Mind: The neurobiology of the tauopathies (2003) (0)
Tauopathy-induced retinal dysfunction in the P301S mutant human tau transgenic mouse (2013) (0)
GENE MAP OF THE MSTD (MULTIPLE SYSTEM TAUOPATHY WITH PRESENILE DEMENTIA) REGION ON HUMAN CHROMOSOME 17q21–22 (1997) (0)
Chapter 4 Tau Protein and the Dementias (2007) (0)
Structures of filaments from Pick’s disease reveal a novel tau protein fold (2018) (0)
Globular glial tauopathy type 1 tau filament (2021) (0)
Straight filament from sporadic Alzheimer's disease brain (2018) (0)
Cryo-EM structures of chronic traumatic encephalopathy tau filaments with PET ligand flortaucipir (2022) (0)
Straight filament in Alzheimer's disease brain (2017) (0)
303 Molecular dissection of the paired helical filament (1996) (0)
Cell-mediated Neuroprotection in P301S Human Tau Transgenic Mice, a Model of Human Tauopathy (2010) (0)
Assembly of α-synuclein and neurodegeneration in the central nervous system of heterozygous M83 mice following the peripheral administration of α-synuclein seeds (2021) (0)
Cryo-EM structure of heparin-induced 2N4R tau twister filaments (2019) (0)
Letter: White cells and uric acid in alcoholism. (1975) (0)
Correction: Piericidin A Aggravates Tau Pathology in P301S Transgenic Mice (2015) (0)
Theswitch oftauprotein toan Alzheimer-like state includes thephosphorylation oftwoserine- proline motifs upstreamofthemicrotubule binding region (1992) (0)
TRANSECTION OF TARGETED AXONAL PATHWAYS INHIBITS NETWORK SPREAD OF TAU PATHOLOGY IN A P301S MODEL OF TAU PROPAGATION (2016) (0)
Author response: Inhibition of synucleinopathic seeding by rationally designed inhibitors (2019) (0)
NEURONS WITH TAU AGGREGATES EXPOSE PHOSPHATIDYLSERINE AND ARE PHAGOCYTOSED LIVE BY MICROGLIA (2018) (0)
Paired helical filament in Alzheimer's disease brain (2017) (0)
SYMPOSIUM: Tau Protein and Neurodegeneration (2007) (0)
CHARACTERISATION OF TAU FROM P301S MOUSE REVEALS THAT SEED COMPETENT TAU COMPRISE SMALL FIBRILS COMPOSED OF HYPERPHOSPHORYLATED TAU (2014) (0)
Neurodegeneration and the ordered assembly of α-synuclein (2017) (0)
Discussion on the session on neurochemistry of nociception: report by M. Goedert (1985) (0)
Cryo-EM structure of heparin-induced 2N4R tau jagged filaments (2019) (0)
Multiple system atrophy Type II-1 alpha-synuclein filament (2020) (0)
DEVELOPING IN VIVO MODELS OF TAU PROPAGATION WHICH ARE RELEVANT TO HUMAN DISEASE PATHOGENESIS AND APPLICABLE TO PRE-CLINICAL DRUG DISCOVERY (2017) (0)
Propagation of Tau aggregates (2017) (0)
Rapid and progressive neurofibrillary tangle pathology in a novel in vivo model of tau propagation: Pattern of spread is determined by structural connectivity not spatial proximity (2013) (0)
Theabnormal phosphorylation oftauprotein atSer-202 in Alzheimer disease recapitulates phosphorylation during development (fetal tau/adult tau/paired helical fIlament/neuropathology) (1993) (0)
Dramatic increases in phosphorylation of tau only on specific epitopes correlates with decline in motor function in aged P301S mice (2010) (0)
Cryo-EM structure of TypeII tau filaments extracted from the brains of individuals with Corticobasal degeneration (2020) (0)
Pronase-treated paired helical filament in Alzheimer's disease brain (2017) (0)
Editorial Board (2010) (0)
Rodent models for Alzheimer disease (2018) (0)
Aaron Klug and the study of Alzheimer's disease (2019) (0)
Cryo-EM structure of heparin-induced 2N4R tau snake filaments (2019) (0)
Table of Contents (1995) (0)
Characterization of Molecular Pathology of Alzheimer's Disease (1989) (0)
Prion-like behaviour of tau protein (2019) (0)
Assembly of recombinant tau into filaments identical 1 to those of Alzheimer ' s disease and chronic traumatic 2 encephalopathy 3 4 (0)
Globular glial tauopathy type 3 tau filament (2021) (0)

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