Michele De Palma
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Italian biologist
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Michele De Palmabiology Degrees
Biology
#13413
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Biotechnology
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#270
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Molecular Biology
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Biology
Michele De Palma's Degrees
- Bachelors Biology University of Milan
- Masters Biotechnology University of Milan
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Why Is Michele De Palma Influential?
(Suggest an Edit or Addition)According to Wikipedia, Michele 'Miki' De Palma is an Italian biologist and a professor at EPFL . He is known for his work on the role of macrophages in cancer progression and the discovery of Tie2-expressing angiogenic monocytes.
Michele De Palma's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors. (2005) (1304)
- Microenvironmental regulation of tumour angiogenesis (2017) (1081)
- Macrophage regulation of tumor responses to anticancer therapies. (2013) (909)
- HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF. (2011) (641)
- Targeting exogenous genes to tumor angiogenesis by transplantation of genetically modified hematopoietic stem cells (2003) (602)
- Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells. (2011) (573)
- FcRgamma activation regulates inflammation-associated squamous carcinogenesis. (2010) (501)
- Identification of proangiogenic TIE2-expressing monocytes (TEMs) in human peripheral blood and cancer. (2007) (496)
- Endogenous RNAs modulate microRNA sorting to exosomes and transfer to acceptor cells. (2014) (487)
- Dual angiopoietin-2 and VEGFA inhibition elicits antitumor immunity that is enhanced by PD-1 checkpoint blockade (2017) (383)
- Consensus guidelines for the use and interpretation of angiogenesis assays (2018) (370)
- A distinguishing gene signature shared by tumor-infiltrating Tie2-expressing monocytes, blood "resident" monocytes, and embryonic macrophages suggests common functions and developmental relationships. (2009) (352)
- Perivascular M2 Macrophages Stimulate Tumor Relapse after Chemotherapy. (2015) (331)
- Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models (2018) (316)
- Angiopoietin-2 regulates gene expression in TIE2-expressing monocytes and augments their inherent proangiogenic functions. (2010) (310)
- Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis (2011) (293)
- Tie2-expressing monocytes: regulation of tumor angiogenesis and therapeutic implications. (2007) (277)
- Correction of metachromatic leukodystrophy in the mouse model by transplantation of genetically modified hematopoietic stem cells. (2004) (273)
- Tie2-expressing monocytes and tumor angiogenesis: regulation by hypoxia and angiopoietin-2. (2007) (255)
- Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis. (2008) (254)
- TIE2-expressing macrophages limit the therapeutic efficacy of the vascular-disrupting agent combretastatin A4 phosphate in mice. (2011) (220)
- Engineering dendritic cell vaccines to improve cancer immunotherapy (2019) (217)
- The interplay between macrophages and angiogenesis in development, tissue injury and regeneration. (2011) (208)
- Role of angiopoietin-2 in adaptive tumor resistance to VEGF signaling blockade. (2014) (207)
- Suppression of microRNA activity amplifies IFN-γ-induced macrophage activation and promotes anti-tumour immunity (2016) (203)
- Transplanted neural stem/precursor cells instruct phagocytes and reduce secondary tissue damage in the injured spinal cord. (2012) (202)
- T cell–induced CSF1 promotes melanoma resistance to PD1 blockade (2018) (199)
- miR-511-3p modulates genetic programs of tumor-associated macrophages. (2012) (194)
- Epidermal growth factor receptor expression identifies functionally and molecularly distinct tumor-initiating cells in human glioblastoma multiforme and is required for gliomagenesis. (2010) (192)
- Angiopoietin 2 Stimulates TIE2-Expressing Monocytes To Suppress T Cell Activation and To Promote Regulatory T Cell Expansion (2011) (190)
- Promoter trapping reveals significant differences in integration site selection between MLV and HIV vectors in primary hematopoietic cells. (2005) (174)
- MicroRNA-mediated control of macrophages and its implications for cancer. (2013) (167)
- Macrophage regulation of tumor angiogenesis: implications for cancer therapy. (2011) (166)
- Tie2 identifies a hematopoietic monocytes required for tumor lineage of proangiogenic vessel formation and a mesenchymal population of pericyte progenitors (2005) (158)
- Elusive identities and overlapping phenotypes of proangiogenic myeloid cells in tumors. (2010) (155)
- The biology of personalized cancer medicine: Facing individual complexities underlying hallmark capabilities (2012) (143)
- Regulation of Macrophage Arginase Expression and Tumor Growth by the Ron Receptor Tyrosine Kinase (2011) (138)
- Targeting vascular pericytes in hypoxic tumors increases lung metastasis via angiopoietin-2. (2015) (136)
- Rapid activation of tumor-associated macrophages boosts preexisting tumor immunity (2018) (129)
- Primary Human and Rat β-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity (2016) (123)
- Role of haematopoietic cells and endothelial progenitors in tumour angiogenesis. (2006) (121)
- Cancer: Macrophages limit chemotherapy (2011) (120)
- Precision Targeting of Tumor Macrophages with a CD206 Binding Peptide (2017) (116)
- Systemic and Targeted Delivery of Semaphorin 3A Inhibits Tumor Angiogenesis and Progression in Mouse Tumor Models (2011) (114)
- Perivascular macrophages in health and disease (2018) (112)
- In vivo targeting of tumor endothelial cells by systemic delivery of lentiviral vectors. (2003) (106)
- Tie2-expressing monocytes (TEMs): novel targets and vehicles of anticancer therapy? (2009) (103)
- TIE2-expressing monocytes/macrophages regulate revascularization of the ischemic limb (2013) (98)
- Proangiogenic Tie2(+) macrophages infiltrate human and murine endometriotic lesions and dictate their growth in a mouse model of the disease. (2011) (94)
- Angiopoietin-2 TIEs Up Macrophages in Tumor Angiogenesis (2011) (91)
- Reciprocal interactions between endothelial cells and macrophages in angiogenic vascular niches. (2013) (88)
- Genetic Engineering of Hematopoiesis for Targeted IFN-α Delivery Inhibits Breast Cancer Progression (2014) (87)
- Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles (2019) (86)
- Targeting Macrophages Sensitizes Chronic Lymphocytic Leukemia to Apoptosis and Inhibits Disease Progression. (2016) (82)
- Transduction of a gene expression cassette using advanced generation lentiviral vectors. (2002) (81)
- The Selective Tie2 Inhibitor Rebastinib Blocks Recruitment and Function of Tie2Hi Macrophages in Breast Cancer and Pancreatic Neuroendocrine Tumors (2017) (76)
- Perivascular Macrophages Limit Permeability (2016) (75)
- Imaging-based spectrometer-less optofluidic biosensors based on dielectric metasurfaces for detecting extracellular vesicles (2021) (66)
- Optimized antiangiogenic reprogramming of the tumor microenvironment potentiates CD40 immunotherapy (2019) (53)
- FcR g Activation Regulates Inflammation-Associated Squamous Carcinogenesis (2011) (53)
- Biology and therapeutic targeting of tumour‐associated macrophages (2020) (50)
- PHD2 regulates arteriogenic macrophages through TIE2 signalling (2013) (47)
- Bimodal CD40/Fas-Dependent Crosstalk between iNKT Cells and Tumor-Associated Macrophages Impairs Prostate Cancer Progression. (2018) (47)
- Guidance Molecule SEMA3A Restricts Tumor Growth by Differentially Regulating the Proliferation of Tumor-Associated Macrophages. (2016) (44)
- Reprogramming Tumor Blood Vessels for Enhancing Immunotherapy. (2017) (43)
- EVIR: Chimeric receptors that enhance dendritic cell cross-dressing with tumor antigens (2018) (41)
- TRIM33 switches off Ifnb1 gene transcription during the late phase of macrophage activation (2015) (38)
- CD4+ T Cell Activation and Vascular Normalization: Two Sides of the Same Coin? (2017) (37)
- Integrin-Mediated Macrophage Adhesion Promotes Lymphovascular Dissemination in Breast Cancer (2019) (37)
- miR‐135a Inhibits Cancer Stem Cell‐Driven Medulloblastoma Development by Directly Repressing Arhgef6 Expression (2015) (36)
- A new twist on radiation oncology: low-dose irradiation elicits immunostimulatory macrophages that unlock barriers to tumor immunotherapy. (2013) (35)
- Periostin Limits Tumor Response to VEGFA Inhibition. (2018) (34)
- HS1 complexes with cytoskeleton adapters in normal and malignant chronic lymphocytic leukemia B cells (2007) (29)
- miR-511-3p, embedded in the macrophage mannose receptor gene, contributes to intestinal inflammation (2015) (29)
- Overcoming microenvironmental resistance to PD-1 blockade in genetically engineered lung cancer models (2021) (28)
- Antiangiogenic immunotherapy suppresses desmoplastic and chemoresistant intestinal tumors in mice. (2020) (26)
- A double agent in cancer: Deciphering macrophage roles in human tumors (2010) (26)
- Partners in crime: VEGF and IL‐4 conscript tumour‐promoting macrophages (2012) (25)
- A role for angiopoietin-2 in organ-specific metastasis. (2013) (25)
- Cellular magnetic resonance with iron oxide nanoparticles: long-term persistence of SPIO signal in the CNS after transplanted cell death. (2014) (23)
- Cancer: Metastasis risk after anti-macrophage therapy (2014) (21)
- developmental relationships embryonic macrophages suggests common functions and Tie 2-expressing monocytes , blood ' ' resident ' ' monocytes , and A distinguishing gene signature shared by tumor-infiltrating (2009) (21)
- miR-511-3 p Modulates Genetic Programs of Tumor-Associated Macrophages (2012) (19)
- Immune Cells and Inflammatory Mediators as Regulators of Tumor Angiogenesis (2008) (18)
- Macrophage depletion induces edema through release of matrix-degrading proteases and proteoglycan deposition (2021) (18)
- A niche role for periostin and macrophages in glioblastoma (2015) (18)
- The Selective Tie 2 Inhibitor Rebastinib Blocks Recruitment and Function of Tie 2 Hi Macrophages in Breast Cancer and Pancreatic Neuroendocrine Tumors (2017) (15)
- Disentangling the complexity of tumor-derived extracellular vesicles. (2021) (13)
- Cancer Metastasis: Perivascular Macrophages Under Watch. (2015) (12)
- Origins of Brain Tumor Macrophages. (2016) (11)
- Origins of Brain Tumor Macrophages. (2016) (10)
- TIE2‐expressing monocytes: A novel cellular biomarker for hepatocellular carcinoma? (2013) (9)
- Circulating endothelial progenitors and tumor resistance to vascular-targeting therapies. (2012) (8)
- Sequential Bone-Marrow Cell Delivery of VEGFA/S1P Improves Vascularization and Limits Adverse Cardiac Remodeling After Myocardial Infarction in Mice. (2019) (8)
- Macrophage interference on chemotherapy (2019) (7)
- Regulation by Hypoxia and Angiopoietin-2 Tie 2-Expressing Monocytes and Tumor Angiogenesis : (2007) (6)
- Partners in crime: VEGF and IL‐4 conscript tumour‐promoting macrophages (2012) (5)
- The role of the immune system in cancer: From mechanisms to clinical applications. (2016) (5)
- Taxonomic Revision of Eudicella White (Coleoptera: Cetoniinae) and Iconographic Catalogue (2009) (4)
- Barcoding analysis and taxonomic revision of Goliathus Lamarck, 1802 (Scarabaeidae, Cetoniinae) (2020) (4)
- Dendritic cell cross‐dressing and tumor immunity (2022) (4)
- Apelin-driven endothelial cell migration sustains intestinal progenitor cells and tumor growth (2022) (4)
- 2. Promoter Trapping Reveals Significant Differences in Integration Site Selection Between MLV and HIV Vectors (2004) (3)
- Antagonizing metastasis (2010) (3)
- Boosting dendritic cell nanovaccines (2022) (3)
- The role of the immune system in cancer: From mechanisms to clinical applications. (2016) (3)
- MACROPHAGE SKEWING BY PHD 2 HAPLODEFICIENCY PREVENTS ISCHEMIA BY INDUCING ARTERIOGENESIS (2012) (3)
- Tweaking the DNA of myeloid cells curbs cancer spread (2020) (2)
- Author Correction: Perivascular macrophages in health and disease (2021) (2)
- DICERing macrophages for reprogramming TAMs (2016) (2)
- The angiopoietin-Tie2 pathway regulates Purkinje cell dendritic morphogenesis in a cell-autonomous manner (2021) (2)
- Taxonomic Revision of Megalorhina Westwood and subgeneric classification of Mecynorhina Hope (Coleoptera: Cetoniinae) (2010) (2)
- Description of Fornasinius hermes sp. nov. (Coleoptera, Cetoniidae, Goliathini) (2017) (2)
- A LIGHTning Strike to the Metastatic Niche. (2020) (2)
- Abstract 12860: TIE2-Expressing Monocytes/Macrophages Promote Recovery from Tissue Ischaemia (2012) (1)
- Lymphoma Chemotherapy: Hungry Macrophages Strike the Final Blow. (2019) (1)
- Functions Monocytes and Augments Their Inherent Proangiogenic Angiopoietin-2 Regulates Gene Expression in TIE 2-Expressing (2010) (1)
- Role of extracellular vesicles in chemotherapy-induced lung metastasis (2020) (1)
- Tumour-associated macrophages (2012) (1)
- Exosomes, microvesicles, and other extracellular vesicles-a Keystone Symposia report. (2023) (1)
- Alzheimer’s drug turns macrophages against cancer (2021) (1)
- 439. Genetic Manipulation of Liver Sinusoidal Endothelial Cells (LSEC) and Repopulation of the Mouse Liver with Transplanted LSEC Has Therapeutic Implications (2006) (0)
- Use of PCR for detecting Border disease virus in ewe's milk. (1998) (0)
- Abstract IA15: Overcoming tumor resistance to VEGF blockade by co-targeting ANG2/TIE2 signaling and macrophages (2015) (0)
- Forced Expression Of Tie2 Enhances The Angiogenic Potential Of Monocytes/Macrophages (2015) (0)
- Micromanaging restenosis by therapeutic inhibition of miR-92a. (2014) (0)
- Taxonomic revision of genus Fornasinius Bertoloni, 1853 with description of new taxa (Scarabaeidae: Cetoniinae) (2018) (0)
- Abstract 11779: Tie2-Expressing Macrophages Induced by PHD2 Haplodeficiency Prevents Ischemic Damage After Limb Ischemia and Myocardial Infarction by Inducing Collateral Artery Growth (2011) (0)
- Defining and targeting tumor-associated macrophages in malignant mesothelioma (2023) (0)
- Consensus guidelines for the use and interpretation of angiogenesis assays (2018) (0)
- Receptor Tyrosine Kinase Expression and Tumor Growth by the Ron Regulation of Macrophage Arginase (2011) (0)
- Promote Regulatory T Cell Expansion Monocytes To Suppress T Cell Activation and To Angiopoietin 2 Stimulates TIE2-Expressing (2011) (0)
- Imaging-based Optofluidic Biosensors Enabled by All-dielectric metasurfaces (2021) (0)
- Description of a new Eudicella daphnis (Buquet) from Eastern Africa (Scarabaeidae, Cetoniinae) (2010) (0)
- Identification of Scarabaeus micans Drury and taxonomic notes on Dicronorhina Hope, with description of a new species (Coleoptera, Scarabaeidae, Cetoniinae) (2011) (0)
- Mo1824 miR-511-3p, Embedded in the Macrophage Mannose Receptor Gene, Contributes to Experimental Colitis (2015) (0)
- Abstract 1366: Inhibition of Tie2+ macrophage infiltration into tumors in combination with CA-4-P therapy may enhance the clinical efficacy of this vascular disrupting agent (2010) (0)
- 446. Tie2 Expression Defines an Integrated System of Cell Types Specifically Involved in Angiogenesis, and Provides a Platform for Targeted Gene Delivery to Tumors (2005) (0)
- Expansionand To Promote Regulatory T Cell Monocytes To Suppress T Cell Activation Angiopoietin 2 Stimulates TIE2-Expressing (2011) (0)
- Abstract SY15-01: Tumor agnostic dendritic cell vaccines (2023) (0)
- Functional Gene Set Analysis Predicts Novel Cellular And Molecular Immune Mediators Of Impaired Diabetic Wound Healing (2017) (0)
- Precision Targeting of Tumor Macrophages with a CD206 Binding Peptide (2017) (0)
- [Gene therapy in oncology: applications to lung cancer]. (1996) (0)
- Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models (2018) (0)
- Perivascular macrophages in health and disease (2018) (0)
- Serological correlation between the strains of feline calicivirus (FCV) isolated in Italy and F9 vaccine strains. (2000) (0)
- Medical and Personal Characteristics Can Predict the Risk of Lung Metastasis. (2023) (0)
- Remarks on the status of Fornasinius insignis ab. funereus Burgeon, 1937 (Coleoptera, Scarabaeidae, Cetoniinae, Goliathini) (2018) (0)
- Macrophage interference on chemotherapy (2019) (0)
- Vascular Modulatory Functions of Macrophages (2014) (0)
- Identification of the Goliath beetles Fornasinius fornasini Bertoloni and Fornasinius hauseri Kraatz (Scarabaeidae: Cetoniinae) (2018) (0)
- Molecular Profiling and Fu nctional Analysis of Macrophage-Derived Tumor Extracellular Vesicles Graphical (2019) (0)
- 41. Ex Vivo Gene Therapy Provides a Unique Therapeutic Benefit and Corrects Metachromatic (MLD) and Globoid (GLD) Leukodystrophy in the Mouse Models (2004) (0)
- Abstract SY27-02: Heterogeneity of tumor-associated macrophages: Implications for antiangiogenic therapy (2010) (0)
- Integrin-Mediated Macrop hage Adhesion Promotes Lymphovascular Dissemination in Breast Cancer Graphical (2019) (0)
- Abstract 75: Determinants of tumor resistance to anti-angiogenic immunotherapy in mouse models of Kras-mutant NSCLC (2021) (0)
- Coexpression Network Analysis Of Time-Course Transcriptional Response During Cutaneous Wound Healing In A Murine Model Of Diabetes (2017) (0)
- BACR/BMS Special Conference ‘‘Tumour Vasculature: New Targets & Therapies’’ 25th/28th June 2006, Cirencester, UK (2006) (0)
- ermal Growth Factor Receptor Expression Identifies ctionally and Molecularly Distinct Tumor-Initiating Cells uman Glioblastoma Multiforme and Is Required (2010) (0)
- 50PExtracellular vesicle-internalizing receptors (EVIRs) for dendritic cell-based tumor vaccines (2017) (0)
- Targeting LRG1 boosts immunotherapy. (2021) (0)
- Tweaking the DNA of myeloid cells curbs cancer spread (2020) (0)
- O4 Mechanisms of lung cancer hyper-progression promoted by PD-1 immune checkpoint blockade (2020) (0)
- 5 INVITED Role of haematopoietic cells in tumour angiogenesis: from discovery to targeted cancer gene therapy (2007) (0)
- Giulia Escobar Inhibits Breast Cancer Progression Delivery α Genetic Engineering of Hematopoiesis for Targeted IFN - (2013) (0)
- Abstract IA15: Vascular reprogramming for enhancing cancer immunotherapy (2020) (0)
- Dual Angiopoietin-2/VEGFA Inhibition Elicits Anti-Tumor Immunity That is Enhanced by PD1 Blockade (2017) (0)
- Cancer esearch cular and Cellular Pathobiology ermal Growth Factor Receptor Expression Identifies ctionally and Molecularly Distinct Tumor-Initiating Cells uman Glioblastoma Multiforme and Is Required R Gliomagenesis (2010) (0)
- Macrophage-derived Vascular Endothelial Growth Factor C re-directs hematogenous metastatic dissemination by normalizing the tumor vasculature (2017) (0)
- Explorer Stimulation of Tumor Relapse After Chemotherapy by Perivascular , Alternatively Activated Macrophages (2015) (0)
- Abstract 2849: Tie2-expressing macrophages (TEM) depletion may enhance the clinical efficacy of combretastatin A-4-phosphate (CA-4-P) (2011) (0)
- TIE2-expressing monocytes regulate revascularisation of the ischaemic limb (2013) (0)
- Macrophage reprogramming for anticancer therapy (2016) (0)
- Assessing metastasis risk after pre-operative anti-angiogenic therapy (2014) (0)
- Monocyte/Macrophage Lineage Cells Significantly Influence The Survival And Proliferation Of Chronic Lymphocytic Leukemia (Cll) Cells (2014) (0)
- All-dielectric Metasurfaces Enabling Imaging-based Real-time Biosensing (2021) (0)
- Abstract A48: Interactions between lymphatic vessels and cancer-associated fibroblasts in tumor immunity (2016) (0)
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What Schools Are Affiliated With Michele De Palma?
Michele De Palma is affiliated with the following schools:
