Michele Vendruscolo
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Italian British physicist
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Why Is Michele Vendruscolo Influential?
(Suggest an Edit or Addition)According to Wikipedia, Michele Vendruscolo is an Italian British physicist working in the UK, noted for his theoretical and experimental work on protein folding, misfolding and aggregation. Education Vendruscolo is a graduate in physics of the University of Trieste . He received a Master of Science and a PhD in condensed matter physics at the International School for Advanced Studies in Trieste, Italy. He then worked as a postdoctoral researcher, at the Weizmann Institute, Israel with Eytan Domany as a supervisor and at the University of Oxford under the supervision of Chris Dobson.
Michele Vendruscolo's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism (2013) (1037)
- The amyloid state and its association with protein misfolding diseases (2014) (984)
- An Analytical Solution to the Kinetics of Breakable Filament Assembly (2009) (959)
- The amyloid state and its association with protein misfolding diseases (2014) (903)
- Role of Intermolecular Forces in Defining Material Properties of Protein Nanofibrils (2007) (657)
- Simultaneous determination of protein structure and dynamics (2005) (650)
- Amyloid-like Aggregates Sequester Numerous Metastable Proteins with Essential Cellular Functions (2011) (645)
- ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function (2015) (620)
- PARMBSC1: A REFINED FORCE-FIELD FOR DNA SIMULATIONS (2015) (611)
- Mapping long-range interactions in alpha-synuclein using spin-label NMR and ensemble molecular dynamics simulations. (2005) (605)
- Prediction of "aggregation-prone" and "aggregation-susceptible" regions in proteins associated with neurodegenerative diseases. (2005) (576)
- FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions (2018) (521)
- Protein structure determination from NMR chemical shifts (2007) (512)
- Solution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregation (2014) (494)
- Atomic structure and hierarchical assembly of a cross-β amyloid fibril (2013) (453)
- Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation. (2015) (448)
- Prediction of aggregation-prone regions in structured proteins. (2008) (443)
- Promoting transparency and reproducibility in enhanced molecular simulations (2019) (437)
- Molecular mechanisms of protein aggregation from global fitting of kinetic models (2016) (430)
- Low-populated folding intermediates of Fyn SH3 characterized by relaxation dispersion NMR (2004) (416)
- Three key residues form a critical contact network in a protein folding transition state (2001) (413)
- Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers (2017) (398)
- From macroscopic measurements to microscopic mechanisms of protein aggregation. (2012) (397)
- Small-world view of the amino acids that play a key role in protein folding. (2002) (367)
- Metastability of native proteins and the phenomenon of amyloid formation. (2011) (357)
- Structure of an Intermediate State in Protein Folding and Aggregation (2012) (346)
- Determination of secondary structure populations in disordered states of proteins using nuclear magnetic resonance chemical shifts. (2012) (337)
- Widespread Proteome Remodeling and Aggregation in Aging C. elegans (2015) (328)
- Direct Observation of the Three Regions in α-Synuclein that Determine its Membrane-Bound Behaviour (2014) (320)
- Prediction of the absolute aggregation rates of amyloidogenic polypeptide chains. (2004) (309)
- The Zyggregator method for predicting protein aggregation propensities. (2008) (308)
- Widespread Proteome Remodeling and Aggregation in Aging C. elegans (2017) (304)
- Nucleated polymerization with secondary pathways. I. Time evolution of the principal moments. (2011) (291)
- The CamSol method of rational design of protein mutants with enhanced solubility. (2015) (286)
- Life on the edge: a link between gene expression levels and aggregation rates of human proteins. (2007) (271)
- Recovery of protein structure from contact maps. (1997) (270)
- The molecular chaperone Brichos breaks the catalytic cycle that generates toxic Aβ oligomers (2015) (261)
- Fast and accurate predictions of protein NMR chemical shifts from interatomic distances. (2009) (244)
- Principles of protein structural ensemble determination. (2017) (238)
- RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether (2019) (236)
- Widespread aggregation and neurodegenerative diseases are associated with supersaturated proteins. (2013) (221)
- Structural Reorganisation and Potential Toxicity of Oligomeric Species Formed during the Assembly of Amyloid Fibrils (2007) (210)
- Mutations associated with familial Parkinson’s disease alter the initiation and amplification steps of α-synuclein aggregation (2016) (208)
- A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity (2017) (199)
- pE-DB: a database of structural ensembles of intrinsically disordered and of unfolded proteins (2013) (196)
- Chemical properties of lipids strongly affect the kinetics of the membrane-induced aggregation of α-synuclein (2016) (194)
- Systematic In Vivo Analysis of the Intrinsic Determinants of Amyloid β Pathogenicity (2007) (188)
- Kinetic analysis reveals the diversity of microscopic mechanisms through which molecular chaperones suppress amyloid formation (2016) (187)
- The Amyloid-β Pathway in Alzheimer’s Disease (2021) (185)
- Determination of the free energy landscape of alpha-synuclein using spin label nuclear magnetic resonance measurements. (2009) (185)
- Chemical kinetics for drug discovery to combat protein aggregation diseases. (2014) (181)
- MobiDB 3.0: more annotations for intrinsic disorder, conformational diversity and interactions in proteins (2017) (177)
- Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer’s disease (2016) (167)
- Molecular dynamics simulations with replica-averaged structural restraints generate structural ensembles according to the maximum entropy principle. (2013) (166)
- An anticancer drug suppresses the primary nucleation reaction that initiates the production of the toxic Aβ42 aggregates linked with Alzheimer’s disease (2016) (165)
- Structural basis of synaptic vesicle assembly promoted by α-synuclein (2016) (164)
- Effects of α-tubulin acetylation on microtubule structure and stability (2019) (159)
- Nucleated polymerization with secondary pathways. II. Determination of self-consistent solutions to growth processes described by non-linear master equations. (2011) (158)
- Determination of an ensemble of structures representing the denatured state of the bovine acyl-coenzyme a binding protein. (2004) (154)
- Physicochemical principles that regulate the competition between functional and dysfunctional association of proteins (2009) (153)
- Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes (2018) (150)
- Cucurbit[8]uril and blue-box: high-energy water release overwhelms electrostatic interactions. (2013) (149)
- Metainference: A Bayesian inference method for heterogeneous systems (2015) (146)
- Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms (2019) (144)
- The MUMO (minimal under-restraining minimal over-restraining) method for the determination of native state ensembles of proteins (2007) (143)
- Using NMR chemical shifts as structural restraints in molecular dynamics simulations of proteins. (2010) (140)
- Structural approaches to sequence evolution : molecules, networks, populations (2007) (139)
- Relation between native ensembles and experimental structures of proteins. (2006) (138)
- Pairwise contact potentials are unsuitable for protein folding (1998) (137)
- Dynamics of oligomer populations formed during the aggregation of Alzheimer’s Aβ42 peptide (2020) (136)
- Supersaturation is a major driving force for protein aggregation in neurodegenerative diseases. (2015) (135)
- Determination of conformationally heterogeneous states of proteins. (2007) (133)
- A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology (2018) (130)
- Protein folding and misfolding: a paradigm of self–assembly and regulation in complex biological systems (2003) (126)
- Characterization of the free-energy landscapes of proteins by NMR-guided metadynamics (2013) (125)
- Determination of protein structures consistent with NMR order parameters. (2004) (124)
- A Coupled Equilibrium Shift Mechanism in Calmodulin-Mediated Signal Transduction (2008) (124)
- Can a pairwise contact potential stabilize native protein folds against decoys obtained by threading? (2000) (123)
- Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein by Small Molecules as a Potential Therapeutic Strategy for Parkinson’s Disease (2014) (122)
- Dynamic Binding Mode of a Synaptotagmin-1-SNARE Complex in Solution (2015) (120)
- Chemical Kinetics for Bridging Molecular Mechanisms and Macroscopic Measurements of Amyloid Fibril Formation. (2018) (119)
- How to guarantee optimal stability for most representative structures in the protein data bank (2001) (117)
- Characterization of the nucleation barriers for protein aggregation and amyloid formation (2007) (115)
- Rare fluctuations of native proteins sampled by equilibrium hydrogen exchange. (2003) (114)
- ALS mutations in FUS cause neuronal dysfunction and death in Caenorhabditis elegans by a dominant gain-of-function mechanism (2011) (113)
- Inhibition of α-Synuclein Fibrillization by Dopamine Is Mediated by Interactions with Five C-Terminal Residues and with E83 in the NAC Region (2008) (112)
- A structural ensemble of a ribosome-nascent chain complex during co-translational protein folding (2016) (111)
- Chromatin Unfolding by Epigenetic Modifications Explained by Dramatic Impairment of Internucleosome Interactions: A Multiscale Computational Study. (2015) (108)
- Structural interpretation of hydrogen exchange protection factors in proteins: characterization of the native state fluctuations of CI2. (2006) (108)
- The inverted free energy landscape of an intrinsically disordered peptide by simulations and experiments (2015) (104)
- Determination of a transition state at atomic resolution from protein engineering data. (2002) (104)
- Accurate random coil chemical shifts from an analysis of loop regions in native states of proteins. (2009) (104)
- A Generic Mechanism of Emergence of Amyloid Protofilaments from Disordered Oligomeric Aggregates (2008) (102)
- Widespread occurrence of the droplet state of proteins in the human proteome (2020) (102)
- On the mechanism of nonspecific inhibitors of protein aggregation: dissecting the interactions of alpha-synuclein with Congo red and lacmoid. (2009) (101)
- Simultaneous quantification of protein order and disorder. (2017) (99)
- Determination of an ensemble of structures representing the intermediate state of the bacterial immunity protein Im7. (2006) (98)
- Molecular determinants of the aggregation behavior of α‐ and β‐synuclein (2008) (98)
- Secondary nucleation and elongation occur at different sites on Alzheimer’s amyloid-β aggregates (2019) (98)
- Theoretical approaches to protein aggregation. (2006) (98)
- Rational design of antibodies targeting specific epitopes within intrinsically disordered proteins (2015) (97)
- Protein folding and the organization of the protein topology universe. (2005) (96)
- Selective targeting of primary and secondary nucleation pathways in Aβ42 aggregation using a rational antibody scanning method (2017) (95)
- Nucleated polymerization with secondary pathways. III. Equilibrium behavior and oligomer populations. (2011) (94)
- Transition states for protein folding have native topologies despite high structural variability (2004) (94)
- Sequence-based prediction of protein solubility. (2012) (94)
- Mapping of two networks of residues that exhibit structural and dynamical changes upon binding in a PDZ domain protein. (2008) (92)
- Distinct thermodynamic signature of oligomer generation in the aggregation of the amyloid-β peptide (2018) (92)
- Dynamic Visions of Enzymatic Reactions (2006) (91)
- Formation of native and non-native interactions in ensembles of denatured ACBP molecules from paramagnetic relaxation enhancement studies. (2005) (90)
- Towards complete descriptions of the free–energy landscapes of proteins (2005) (89)
- In-Cell NMR Characterization of the Secondary Structure Populations of a Disordered Conformation of α-Synuclein within E. coli Cells (2013) (89)
- Protein solubility and protein homeostasis: a generic view of protein misfolding disorders. (2011) (89)
- Neutral evolution of model proteins: diffusion in sequence space and overdispersion. (1998) (89)
- Blind testing of routine, fully automated determination of protein structures from NMR data. (2012) (89)
- Characterization of the conformational equilibrium between the two major substates of RNase A using NMR chemical shifts. (2012) (88)
- Characterisation of Amyloid Fibril Formation by Small Heat-shock Chaperone Proteins Human αA-, αB- and R120G αB-Crystallins (2007) (87)
- New scenarios of protein folding can occur on the ribosome. (2011) (87)
- Molecular Recognition by Templated Folding of an Intrinsically Disordered Protein (2016) (87)
- In vivo translation rates can substantially delay the cotranslational folding of the Escherichia coli cytosolic proteome (2012) (87)
- A Condensation-Ordering Mechanism in Nanoparticle-Catalyzed Peptide Aggregation (2009) (87)
- Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes (2019) (86)
- Prediction of variable translation rate effects on cotranslational protein folding (2012) (86)
- Spinal motor neuron protein supersaturation patterns are associated with inclusion body formation in ALS (2017) (86)
- A protein homeostasis signature in healthy brains recapitulates tissue vulnerability to Alzheimer’s disease (2016) (85)
- Parapred: antibody paratope prediction using convolutional and recurrent neural networks (2018) (85)
- Microfluidic Diffusion Analysis of the Sizes and Interactions of Proteins under Native Solution Conditions. (2016) (84)
- The Amyloid Phenomenon and Its Significance in Biology and Medicine. (2019) (84)
- Inversion of the Balance between Hydrophobic and Hydrogen Bonding Interactions in Protein Folding and Aggregation (2011) (84)
- Self-templated nucleation in peptide and protein aggregation. (2008) (83)
- Rapid and accurate in silico solubility screening of a monoclonal antibody library (2017) (83)
- Nanobodies raised against monomeric α-synuclein distinguish between fibrils at different maturation stages. (2013) (82)
- Atomic force microscopy for single molecule characterisation of protein aggregation (2019) (81)
- Effective interactions between chaotropic agents and proteins (2005) (81)
- Reduced proteasome activity in the aging brain results in ribosome stoichiometry loss and aggregation (2019) (81)
- Competition between folding, native-state dimerisation and amyloid aggregation in beta-lactoglobulin. (2009) (81)
- Higher order amyloid fibril structure by MAS NMR and DNP spectroscopy. (2013) (81)
- Competition between Intramolecular and Intermolecular Interactions in an Amyloid-Forming Protein (2009) (80)
- Towards a structural biology of the hydrophobic effect in protein folding (2016) (80)
- A clear view of polymorphism, twist, and chirality in amyloid fibril formation. (2013) (80)
- ADP ribosylation adapts an ER chaperone response to short-term fluctuations in unfolded protein load (2012) (76)
- Structures and relative free energies of partially folded states of proteins (2003) (75)
- Transient tertiary structure formation within the ribosome exit port. (2010) (75)
- Understanding the influence of codon translation rates on cotranslational protein folding. (2014) (74)
- Structural Ensembles of Membrane-bound α-Synuclein Reveal the Molecular Determinants of Synaptic Vesicle Affinity (2016) (74)
- Proteome-wide observation of the phenomenon of life on the edge of solubility (2019) (73)
- Trigger factor slows co-translational folding through kinetic trapping while sterically protecting the nascent chain from aberrant cytosolic interactions. (2012) (73)
- Structural Approaches to Sequence Evolution (2007) (71)
- Structure-based prediction of methyl chemical shifts in proteins (2011) (71)
- Targeting disordered proteins with small molecules using entropy. (2015) (71)
- Kinetic modelling indicates that fast-translating codons can coordinate cotranslational protein folding by avoiding misfolded intermediates (2014) (71)
- A transcriptional signature of Alzheimer’s disease is associated with a metastable subproteome at risk for aggregation (2016) (70)
- Principal eigenvector of contact matrices and hydrophobicity profiles in proteins (2004) (70)
- The s2D method: simultaneous sequence-based prediction of the statistical populations of ordered and disordered regions in proteins. (2015) (69)
- Protein Dynamics: Moore's Law in Molecular Biology (2011) (69)
- Experimental free energy surfaces reveal the mechanisms of maintenance of protein solubility (2011) (68)
- Time averaging of NMR chemical shifts in the MLF peptide in the solid state. (2010) (68)
- Transition state contact orders correlate with protein folding rates. (2005) (68)
- A PDZ domain recapitulates a unifying mechanism for protein folding (2007) (66)
- Statistical mechanics of the denatured state of a protein using replica-averaged metadynamics. (2014) (66)
- Prediction by Graph Theoretic Measures of Structural Effects in Proteins Arising from Non-Synonymous Single Nucleotide Polymorphisms (2008) (65)
- Identification of small-molecule binding pockets in the soluble monomeric form of the Aβ42 peptide. (2013) (65)
- Kinetic fingerprints differentiate the mechanisms of action of anti-Aβ antibodies (2020) (65)
- Protein folding using contact maps. (1999) (65)
- Prediction of local structural stabilities of proteins from their amino acid sequences. (2007) (65)
- Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine. (2018) (65)
- Connectivity of Neutral Networks, Overdispersion, and Structural Conservation in Protein Evolution (2001) (64)
- A relationship between mRNA expression levels and protein solubility in E. coli. (2009) (64)
- Simultaneous Determination of Protein Structure and Dynamics Using Cryo-Electron Microscopy (2017) (64)
- Third generation antibody discovery methods: in silico rational design. (2018) (64)
- The Mechanism of Folding of Im7 Reveals Competition between Functional and Kinetic Evolutionary Constraints (2009) (64)
- β-Synuclein suppresses both the initiation and amplification steps of α-synuclein aggregation via competitive binding to surfaces (2016) (64)
- Protein homeostasis of a metastable subproteome associated with Alzheimer’s disease (2017) (63)
- Toward an accurate determination of free energy landscapes in solution states of proteins. (2009) (63)
- Cyclophilin A catalyzes proline isomerization by an electrostatic handle mechanism (2014) (62)
- Common Regulatory Pathways Mediate Activity of MicroRNAs Inducing Cardiomyocyte Proliferation (2019) (62)
- Replica-Averaged Metadynamics. (2013) (61)
- Molecular dynamics studies of the process of amyloid aggregation of peptide fragments of transthyretin. (2004) (61)
- In vitro and in silico assessment of the developability of a designed monoclonal antibody library (2019) (60)
- Comparison of successive transition states for folding reveals alternative early folding pathways of two homologous proteins (2008) (60)
- Observation of an α-synuclein liquid droplet state and its maturation into Lewy body-like assemblies (2020) (60)
- Metadynamic metainference: Enhanced sampling of the metainference ensemble using metadynamics (2016) (60)
- Networks in cell biology (2010) (60)
- The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress α-synuclein aggregation (2017) (59)
- Native and non‐native interactions along protein folding and unfolding pathways (2002) (58)
- BPPred: A Web‐based computational tool for predicting biophysical parameters of proteins (2006) (58)
- Inhibition of protein crystallization by evolutionary negative design (2004) (58)
- Determination of the folding transition states of barnase by using PhiI-value-restrained simulations validated by double mutant PhiIJ-values. (2005) (58)
- Factors that affect the degree of twist in beta-sheet structures: a molecular dynamics simulation study of a cross-beta filament of the GNNQQNY peptide. (2009) (58)
- Generic nature of the condensed states of proteins (2021) (58)
- The distribution of residues in a polypeptide sequence is a determinant of aggregation optimized by evolution. (2007) (58)
- Correlation between mRNA expression levels and protein aggregation propensities in subcellular localisations. (2009) (57)
- Structure determination of protein-protein complexes using NMR chemical shifts: case of an endonuclease colicin-immunity protein complex. (2008) (57)
- Single molecule secondary structure determination of proteins through infrared absorption nanospectroscopy (2020) (55)
- Automated assignment of SCOP and CATH protein structure classifications from FSSP scores (2001) (55)
- A Simple Lattice Model That Captures Protein Folding, Aggregation and Amyloid Formation (2014) (55)
- A Relationship between the Transient Structure in the Monomeric State and the Aggregation Propensities of α-Synuclein and β-Synuclein (2014) (55)
- Nanobodies raised against monomeric ɑ-synuclein inhibit fibril formation and destabilize toxic oligomeric species (2017) (55)
- Soluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer’s disease progression (2019) (54)
- Structural characterization of a misfolded intermediate populated during the folding process of a PDZ domain (2010) (54)
- Small-molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer’s disease (2019) (53)
- A statistical mechanical method to optimize energy functions for protein folding. (2000) (53)
- Physicochemical determinants of chaperone requirements. (2010) (53)
- Proteome-level interplay between folding and aggregation propensities of proteins. (2010) (53)
- Chemical biology: More charges against aggregation (2007) (52)
- The H50Q Mutation Induces a 10-fold Decrease in the Solubility of α-Synuclein* (2014) (51)
- Nucleated Polymerisation in the Presence of Pre-Formed Seed Filaments (2011) (51)
- Self-consistent determination of the transition state for protein folding: Application to a fibronectin type III domain (2003) (51)
- Similarities in the thermodynamics and kinetics of aggregation of disease‐related Aβ(1–40) peptides (2007) (51)
- Determination of structural fluctuations of proteins from structure-based calculations of residual dipolar couplings (2012) (51)
- Sequence Specificity in the Entropy-Driven Binding of a Small Molecule and a Disordered Peptide. (2017) (51)
- Structural characterization of the interaction of α-synuclein nascent chains with the ribosomal surface and trigger factor (2016) (50)
- Interpreting Dynamically-Averaged Scalar Couplings in Proteins (2005) (50)
- Validity of Gō models: comparison with a solvent-shielded empirical energy decomposition. (2002) (50)
- Intrinsic determinants of neurotoxic aggregate formation by the amyloid beta peptide. (2010) (50)
- Effects of the known pathogenic mutations on the aggregation pathway of the amyloidogenic peptide of apolipoprotein A-I. (2011) (50)
- Latent analysis of unmodified biomolecules and their complexes in solution with attomole detection sensitivity. (2015) (49)
- Networks of Dynamic Allostery Regulate Enzyme Function. (2017) (49)
- Comparison of the transition states for folding of two Ig-like proteins from different superfamilies. (2004) (49)
- Druggability of Intrinsically Disordered Proteins. (2015) (48)
- Determination of Structural Ensembles of Proteins: Restraining vs Reweighting. (2018) (48)
- Position‐Dependent Electrostatic Protection against Protein Aggregation (2009) (48)
- Structure of a low-population binding intermediate in protein-RNA recognition (2016) (48)
- Protein folding: bringing theory and experiment closer together. (2003) (48)
- Methods of probing the interactions between small molecules and disordered proteins (2017) (48)
- Sequence-Based Prediction of Fuzzy Protein Interactions (2020) (48)
- Twisting transition between crystalline and fibrillar phases of aggregated peptides. (2012) (47)
- Reconstruction of protein structures from a vectorial representation. (2004) (47)
- Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability (2016) (46)
- Identification of Small Molecule Inhibitors of Tau Aggregation by Targeting Monomeric Tau As a Potential Therapeutic Approach for Tauopathies (2015) (46)
- Scaling behaviour and rate-determining steps in filamentous self-assembly† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc01965c Click here for additional data file. (2017) (46)
- A tensor-free method for the structural and dynamical refinement of proteins using residual dipolar couplings. (2014) (46)
- A protein evolution model with independent sites that reproduces site-specific amino acid distributions from the Protein Data Bank (2006) (45)
- Inhibition of α-Synuclein Fibril Elongation by Hsp70 Is Governed by a Kinetic Binding Competition between α-Synuclein Species. (2017) (45)
- Statistical Properties of Neutral Evolution (2002) (45)
- Comparison of the transition state ensembles for folding of Im7 and Im9 determined using all‐atom molecular dynamics simulations with ϕ value restraints (2003) (45)
- A single ultrasensitive assay for detection and discrimination of tau aggregates of Alzheimer and Pick diseases (2020) (45)
- SAR by kinetics for drug discovery in protein misfolding diseases (2018) (45)
- The A53T mutation is key in defining the differences in the aggregation kinetics of human and mouse α-synuclein. (2011) (45)
- Phage display and kinetic selection of antibodies that specifically inhibit amyloid self-replication (2017) (45)
- Toward an energy function for the contact map representation of proteins (2000) (44)
- Determination of protein structural ensembles using cryo-electron microscopy. (2019) (44)
- Transcriptional regulatory networks (2010) (44)
- Massively parallel C. elegans tracking provides multi-dimensional fingerprints for phenotypic discovery (2018) (44)
- Assessment of the use of NMR chemical shifts as replica-averaged structural restraints in molecular dynamics simulations to characterize the dynamics of proteins. (2013) (43)
- Reversible inhibition of the ClpP protease via an N-terminal conformational switch (2018) (43)
- Importance of metastable states in the free energy landscapes of polypeptide chains. (2007) (43)
- Determination of protein structures in the solid state from NMR chemical shifts. (2008) (42)
- Understanding the frustration arising from the competition between function, misfolding, and aggregation in a globular protein (2014) (42)
- Rational design of a conformation-specific antibody for the quantification of Aβ oligomers (2020) (41)
- Analysis of the distributed computing approach applied to the folding of a small β peptide (2003) (41)
- Structure and dynamics of a partially folded protein are decoupled from its mechanism of aggregation. (2008) (40)
- Proteome folding and aggregation. (2012) (40)
- Million-fold sensitivity enhancement in proteopathic seed amplification assays for biospecimens by Hofmeister ion comparisons (2019) (40)
- Translationally optimal codons associate with aggregation‐prone sites in proteins (2010) (40)
- The docking of synaptic vesicles on the presynaptic membrane induced by α-synuclein is modulated by lipid composition (2021) (39)
- Functional interactions as a survival strategy against abnormal aggregation (2011) (39)
- STATISTICAL PROPERTIES OF CONTACT MAPS (1998) (39)
- The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage (2017) (39)
- Efficient dynamics in the space of contact maps. (1998) (39)
- Prediction of site-specific amino acid distributions and limits of divergent evolutionary changes in protein sequences. (2004) (38)
- Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in Caenorhabditis elegans (2019) (38)
- Stabilization and Characterization of Cytotoxic Aβ40 Oligomers Isolated from an Aggregation Reaction in the Presence of Zinc Ions. (2018) (38)
- Determination of Conformational Equilibria in Proteins Using Residual Dipolar Couplings (2011) (38)
- Characterization of the residual structure in the unfolded state of the Δ131Δ fragment of staphylococcal nuclease (2006) (38)
- Transthyretin Inhibits Primary and Secondary Nucleations of Amyloid-β Peptide Aggregation and Reduces the Toxicity of Its Oligomers (2020) (38)
- Biological function in a non‐native partially folded state of a protein (2008) (37)
- Determination of the structures of distinct transition state ensembles for a β-sheet peptide with parallel folding pathways (2002) (35)
- Monomeric and fibrillar α-synuclein exert opposite effects on the catalytic cycle that promotes the proliferation of Aβ42 aggregates (2017) (35)
- The N-terminal Acetylation of α-Synuclein Changes the Affinity for Lipid Membranes but not the Structural Properties of the Bound State (2020) (35)
- ALMOST: An all atom molecular simulation toolkit for protein structure determination (2014) (35)
- Oxetane Grafts Installed Site‐Selectively on Native Disulfides to Enhance Protein Stability and Activity In Vivo (2017) (35)
- Modified configurational bias Monte Carlo method for simulation of polymer systems (1997) (35)
- Structural Ensemble Modulation upon Small-Molecule Binding to Disordered Proteins. (2018) (35)
- Lack of self-averaging in neutral evolution of proteins. (2002) (34)
- Characterization of the interdomain motions in hen lysozyme using residual dipolar couplings as replica-averaged structural restraints in molecular dynamics simulations. (2013) (34)
- Equilibrium simulations of proteins using molecular fragment replacement and NMR chemical shifts (2014) (34)
- A Fragment-Based Method of Creating Small-Molecule Libraries to Target the Aggregation of Intrinsically Disordered Proteins. (2016) (34)
- Comparison of two optimization methods to derive energy parameters for protein folding: Perceptron and Z score (2000) (33)
- Sequence-based determinants and prediction of fuzzy interactions in protein complexes. (2020) (33)
- Quantifying misfolded protein oligomers as drug targets and biomarkers in Alzheimer and Parkinson diseases (2021) (33)
- The iFly tracking system for an automated locomotor and behavioural analysis of Drosophila melanogaster. (2011) (33)
- Emergence and evolution of an interaction between intrinsically disordered proteins (2017) (33)
- Calculation of mutational free energy changes in transition states for protein folding. (2003) (33)
- Bayesian Weighing of Electron Cryo-Microscopy Data for Integrative Structural Modeling. (2019) (33)
- Detection of early locomotor abnormalities in a Drosophila model of Alzheimer's disease (2011) (32)
- Sequence-based prediction of protein binding mode landscapes (2020) (32)
- Protein Solubility Predictions Using the CamSol Method in the Study of Protein Homeostasis. (2019) (32)
- Trodusquemine displaces protein misfolded oligomers from cell membranes and abrogates their cytotoxicity through a generic mechanism (2020) (32)
- Systematic mapping of free energy landscapes of a growing filamin domain during biosynthesis (2018) (31)
- Analysis of the contributions of ring current and electric field effects to the chemical shifts of RNA bases. (2013) (31)
- STABILITY THRESHOLD AS A SELECTION PRINCIPLE FOR PROTEIN DESIGN (1997) (30)
- Hamiltonian Dynamics of Protein Filament Formation. (2016) (30)
- Widespread remodeling of proteome solubility in response to different protein homeostasis stresses (2020) (30)
- MOAG-4 promotes the aggregation of α-synuclein by competing with self-protective electrostatic interactions (2017) (30)
- The Hsp70 Chaperone System Stabilizes a Thermo-sensitive Subproteome in E. coli. (2019) (30)
- Structure of a low-population intermediate state in the release of an enzyme product (2015) (30)
- Interactions of α-synuclein oligomers with lipid membranes. (2020) (29)
- Structures of the excited states of phospholamban and shifts in their populations upon phosphorylation. (2013) (29)
- Geometry, energetics, and dynamics of hydrogen bonds in proteins: structural information derived from NMR scalar couplings. (2006) (29)
- Determination of the individual roles of the linker residues in the interdomain motions of calmodulin using NMR chemical shifts. (2014) (29)
- Single-Molecule Measurements of Transient Biomolecular Complexes through Microfluidic Dilution (2013) (29)
- Accurate determination of interstrand distances and alignment in amyloid fibrils by magic angle spinning NMR. (2010) (28)
- A Rational Design Strategy for the Selective Activity Enhancement of a Molecular Chaperone toward a Target Substrate. (2015) (27)
- Direct measurement of lipid membrane disruption connects kinetics and toxicity of Aβ42 aggregation (2020) (26)
- Characterisation of amyloid fibril formation by small heat-shock chaperone proteins human alphaA-, alphaB- and R120G alphaB-crystallins. (2007) (26)
- Exploring the role of post‐translational modifications in regulating α‐synuclein interactions by studying the effects of phosphorylation on nanobody binding (2018) (26)
- Probing the Origin of the Toxicity of Oligomeric Aggregates of α-Synuclein with Antibodies (2019) (26)
- Microfluidic deposition for resolving single-molecule protein architecture and heterogeneity (2018) (26)
- A kinetic ensemble of the Alzheimer’s Aβ peptide (2020) (26)
- Thermodynamic and kinetic design principles for amyloid-aggregation inhibitors (2020) (26)
- Infrared nanospectroscopy reveals the molecular interaction fingerprint of an aggregation inhibitor with single Aβ42 oligomers (2020) (26)
- Using side-chain aromatic proton chemical shifts for a quantitative analysis of protein structures. (2011) (26)
- Squalamine and Its Derivatives Modulate the Aggregation of Amyloid-β and α-Synuclein and Suppress the Toxicity of Their Oligomers (2021) (25)
- Influence of the fluctuations of the alignment tensor on the analysis of the structure and dynamics of proteins using residual dipolar couplings (2008) (25)
- Molecular determinants of the interaction of EGCG with ordered and disordered proteins (2018) (25)
- Structural biology. Dynamic visions of enzymatic reactions. (2006) (24)
- High-Dimensional Bak-Sneppen Model (1998) (24)
- Folding of small proteins by Monte Carlo simulations with chemical shift restraints without the use of molecular fragment replacement or structural homology. (2009) (24)
- Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating the aggregation of other proteins (2021) (23)
- Statistical properties of contact vectors. (2001) (23)
- Integration and characterization of solid wall electrodes in microfluidic devices fabricated in a single photolithography step (2013) (23)
- A rationally designed six-residue swap generates comparability in the aggregation behavior of α-synuclein and β-synuclein. (2012) (23)
- The metastability of the proteome of spinal motor neurons underlies their selective vulnerability in ALS (2019) (22)
- Protein regulation: the statistical theory of allostery. (2011) (22)
- A conformational ensemble derived using NMR methyl chemical shifts reveals a mechanical clamping transition that gates the binding of the HU protein to DNA. (2014) (22)
- Looking at structure, stability, and evolution of proteins through the principal eigenvector of contact matrices and hydrophobicity profiles. (2004) (22)
- Folding Lennard‐Jones proteins by a contact potential (1999) (22)
- The Hsc70 disaggregation machinery removes monomer units directly from α-synuclein fibril ends (2020) (22)
- The dynamics of interleukin‐8 and its interaction with human CXC receptor I peptide (2014) (22)
- A Role of Cholesterol in Modulating the Binding of α-Synuclein to Synaptic-Like Vesicles (2020) (21)
- Structure and Dynamics of GeoCyp: A Thermophilic Cyclophilin with a Novel Substrate Binding Mechanism That Functions Efficiently at Low Temperatures. (2015) (21)
- Spatial propagation of protein polymerization. (2014) (21)
- Using Pseudocontact Shifts and Residual Dipolar Couplings as Exact NMR Restraints for the Determination of Protein Structural Ensembles. (2015) (21)
- Comparison of sequence-based and structure-based energy functions for the reversible folding of a peptide. (2005) (21)
- Fast Fluorescence Lifetime Imaging Reveals the Aggregation Processes of α-Synuclein and Polyglutamine in Aging Caenorhabditis elegans. (2019) (21)
- Identification and characterization of PKCγ, a kinase associated with SCA14, as an amyloidogenic protein. (2015) (20)
- Simultaneous NMR characterisation of multiple minima in the free energy landscape of an RNA UUCG tetraloop. (2017) (20)
- Screening of small molecules using the inhibition of oligomer formation in α-synuclein aggregation as a selection parameter (2020) (20)
- Aβ Oligomers Dysregulate Calcium Homeostasis by Mechanosensitive Activation of AMPA and NMDA Receptors (2021) (20)
- A glimpse at the organization of the protein universe. (2005) (20)
- Sequence determinants of the aggregation of proteins within condensates generated by liquid-liquid phase separation (2020) (19)
- A Rationally Designed Hsp70 Variant Rescues the Aggregation-Associated Toxicity of Human IAPP in Cultured Pancreatic Islet β-Cells (2018) (19)
- The physical basis of protein misfolding disorders (2015) (19)
- Structure-Free Validation of Residual Dipolar Coupling and Paramagnetic Relaxation Enhancement Measurements of Disordered Proteins. (2015) (18)
- A method of incorporating rate constants as kinetic constraints in molecular dynamics simulations (2020) (18)
- Structural comparison of the two alternative transition states for folding of TI I27. (2006) (18)
- Amyloid-like Fibrils from an α-Helical Transmembrane Protein (2017) (18)
- Biophysical approaches for the study of interactions between molecular chaperones and protein aggregates (2015) (18)
- Structural differences between toxic and nontoxic HypF-N oligomers. (2018) (18)
- Molecular dynamics ensemble refinement of the heterogeneous native state of NCBD using chemical shifts and NOEs (2018) (17)
- A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers (2021) (17)
- Enzymatic activity in disordered states of proteins. (2010) (17)
- Identification and Structural Characterization of an Intermediate in the Folding of the Measles Virus X Domain* (2016) (17)
- FuzDrop on AlphaFold: visualizing the sequence-dependent propensity of liquid–liquid phase separation and aggregation of proteins (2022) (17)
- Therapeutic Strategies to Reduce the Toxicity of Misfolded Protein Oligomers (2020) (17)
- Critical assessment of protein intrinsic disorder prediction (2021) (17)
- Supersaturated proteins are enriched at synapses and underlie cell and tissue vulnerability in Alzheimer's disease (2019) (17)
- Correction for Perni et al., A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity (2017) (17)
- Fibrillogenic propensity of the GroEL apical domain: A Janus‐faced minichaperone (2012) (17)
- Particle-Based Monte-Carlo Simulations of Steady-State Mass Transport at Intermediate Péclet Numbers (2016) (17)
- Energetics of enzyme stability. (2002) (17)
- Structural Effects of Two Camelid Nanobodies Directed to Distinct C-Terminal Epitopes on α-Synuclein. (2016) (17)
- A relationship between the aggregation rates of α-synuclein variants and the β-sheet populations in their monomeric forms. (2013) (16)
- Towards quantitative predictions in cell biology using chemical properties of proteins. (2008) (16)
- Structural Characterization of the Early Events in the Nucleation-Condensation Mechanism in a Protein Folding Process. (2017) (16)
- Structurally constrained protein evolution: results from a lattice simulation (1999) (16)
- Calculation of the free energy barriers in the oligomerisation of Abeta peptide fragments. (2008) (16)
- Characterization of the Conformational Fluctuations in the Josephin Domain of Ataxin-3 (2014) (16)
- Inherent biophysical properties modulate the toxicity of soluble amyloidogenic light chains. (2019) (16)
- The Kinetics and Mechanisms of Amyloid Formation (2013) (16)
- Sequence determinants of the aggregation of proteins within condensates generated by liquid-liquid phase separation. (2021) (15)
- Soluble amyloid beta-containing aggregates are present throughout the brain at early stages of Alzheimer’s disease (2021) (15)
- Identifying A- and P-site locations on ribosome-protected mRNA fragments using Integer Programming (2018) (15)
- Delivery of Native Proteins into C. elegans Using a Transduction Protocol Based on Lipid Vesicles (2017) (15)
- Analysis of sub-tauc and supra-tauc motions in protein Gbeta1 using molecular dynamics simulations. (2009) (15)
- ADP ribosylation adapts an ER chaperone response to short-term fluctuations in unfolded protein load (2012) (14)
- A Small Molecule Stabilizes the Disordered Native State of the Alzheimer’s Aβ Peptide (2021) (14)
- Enhancement of the Anti-Aggregation Activity of a Molecular Chaperone Using a Rationally Designed Post-Translational Modification (2019) (14)
- 1H, 13C and 15N resonance assignments of human muscle acylphosphatase (2012) (14)
- Mapping the Protein Fold Universe Using the CamTube Force Field in Molecular Dynamics Simulations (2015) (14)
- Assessing motor-related phenotypes of Caenorhabditis elegans with the wide field-of-view nematode tracking platform (2019) (14)
- Using chemical shifts to determine structural changes in proteins upon complex formation. (2011) (14)
- Structural biology: Protein self-assembly intermediates. (2013) (14)
- A Structural Ensemble of a Tau-Microtubule Complex Reveals Regulatory Tau Phosphorylation and Acetylation Mechanisms (2020) (14)
- Identification of an RNA Polymerase III Regulator Linked to Disease-Associated Protein Aggregation (2017) (14)
- Determination of the transition state ensemble for the folding of ubiquitin from a combination of Phi and Psi analyses. (2008) (14)
- Characterisation of transition state structures for protein folding using 'high', 'medium' and 'low' {Phi}-values. (2008) (14)
- Determination of intermediate state structures in the opening pathway of SARS-CoV-2 spike using cryo-electron microscopy† (2020) (13)
- Cholesterol-rich naked mole-rat brain lipid membranes are susceptible to amyloid beta-induced damage in vitro (2020) (13)
- Complexity in lipid membrane composition induces resilience to Aβ42 aggregation. (2020) (13)
- Structure and Dynamics of the Integrin LFA-1 I-Domain in the Inactive State Underlie its Inside-Out/Outside-In Signaling and Allosteric Mechanisms (2015) (13)
- Mutational analysis of the aggregation-prone and disaggregation-prone regions of acylphosphatase. (2009) (12)
- Small soluble α-synuclein aggregates are the toxic species in Parkinson’s disease (2022) (12)
- A geometrical parametrization of C1'-C5' RNA ribose chemical shifts calculated by density functional theory. (2013) (12)
- Molecular dynamics simulations from putative transition states of α‐spectrin SH3 domain (2007) (12)
- Erratum: Widespread Proteome Remodeling and Aggregation in Aging C. elegans (Cell (2015) 161(4) (919–932) (S0092867415003207)(10.1016/j.cell.2015.03.032) (2017) (12)
- Magnetic-Phase Transitions of Ising Surfaces with Modified Surface-Bulk Coupling: a Monte Carlo Study (1992) (12)
- A method of determining RNA conformational ensembles using structure-based calculations of residual dipolar couplings. (2013) (12)
- Determination of the conformational states of strychnine in solution using NMR residual dipolar couplings in a tensor-free approach. (2018) (12)
- Structure and Dynamics of Intrinsically Disordered Proteins. (2015) (11)
- An open-source automated PEG precipitation assay to measure the relative solubility of proteins with low material requirement (2021) (11)
- Rationally Designed Antibodies as Research Tools to Study the Structure–Toxicity Relationship of Amyloid-β Oligomers (2020) (11)
- Surface-Catalyzed Secondary Nucleation Dominates the Generation of Toxic IAPP Aggregates (2021) (11)
- Characterizing the first steps of amyloid formation for the ccbeta peptide. (2008) (11)
- A metastable subproteome underlies inclusion formation in muscle proteinopathies (2019) (11)
- Bacterial production and direct functional screening of expanded molecular libraries for discovering inhibitors of protein aggregation (2019) (11)
- Interactions in the native state of monellin, which play a protective role against aggregation. (2011) (11)
- Archaeal MBF1 binds to 30S and 70S ribosomes via its helix-turn-helix domain. (2014) (11)
- Characterization of the residual structure in the unfolded state of the Delta131Delta fragment of staphylococcal nuclease. (2006) (11)
- Chemical and mechanistic analysis of photodynamic inhibition of Alzheimer's β-amyloid aggregation. (2019) (11)
- Biophysical studies of protein misfolding and aggregation in in vivo models of Alzheimer's and Parkinson's diseases (2020) (10)
- Vrije Universiteit Brussel Nanobodies Raised against Monomeric alpha-Synuclein Distinguish between Fibrils at Different Maturation Stages (2017) (10)
- Assessment of Therapeutic Antibody Developability by Combinations of In Vitro and In Silico Methods. (2022) (10)
- Analysis of the hierarchical structure of the B. subtilis transcriptional regulatory network. (2014) (10)
- A superposition free method for protein conformational ensemble analyses and local clustering based on a differential geometry representation of backbone (2019) (10)
- Systematic Activity Maturation of a Single-Domain Antibody with Non-canonical Amino Acids through Chemical Mutagenesis (2020) (10)
- Kinetic fingerprint of antibody therapies predicts outcomes of Alzheimer clinical trials (2019) (10)
- Derivation of a solubility condition for proteins from an analysis of the competition between folding and aggregation. (2010) (10)
- Subdomain architecture and stability of a giant repeat protein. (2013) (10)
- Modulation of the Interactions Between α-Synuclein and Lipid Membranes by Post-translational Modifications (2021) (10)
- Characterizing Individual Protein Aggregates by Infrared Nanospectroscopy and Atomic Force Microscopy. (2019) (10)
- Quantitative approaches to defining normal and aberrant protein homeostasis. (2009) (10)
- Squalamine and trodusquemine: two natural products for neurodegenerative diseases, from physical chemistry to the clinic. (2021) (9)
- Lipid Homeostasis and Its Links With Protein Misfolding Diseases (2022) (9)
- Making biological membrane resistant to the toxicity of misfolded protein oligomers: a lesson from trodusquemine. (2020) (9)
- Fragment-based computational design of antibodies targeting structured epitopes (2022) (9)
- The binding of the small heat-shock protein αB-crystallin to fibrils of α-synuclein is driven by entropic forces (2021) (9)
- A rationally designed bicyclic peptide remodels Aβ42 aggregation in vitro and reduces its toxicity in a worm model of Alzheimer’s disease (2020) (8)
- An intrinsically disordered motif regulates the interaction between the p47 adaptor and the p97 AAA+ ATPase (2020) (8)
- Protein condensation diseases: therapeutic opportunities (2022) (8)
- Structural Insights into the Calcium-Mediated Allosteric Transition in the C-Terminal Domain of Calmodulin from Nuclear Magnetic Resonance Measurements. (2016) (8)
- Automated Behavioral Analysis of Large C. elegans Populations Using a Wide Field-of-view Tracking Platform. (2018) (8)
- Facile Installation of Post-translational Modifications on the Tau Protein via Chemical Mutagenesis. (2021) (8)
- A Cell- and Tissue-Specific Weakness of the Protein Homeostasis System Underlies Brain Vulnerability to Protein Aggregation (2020) (8)
- Probing the dynamic stalk region of the ribosome using solution NMR (2019) (8)
- Protein structure validation using side-chain chemical shifts. (2012) (8)
- Differential interactome and innate immune response activation of two structurally distinct misfolded protein oligomers. (2019) (7)
- Comparative Studies in the A30P and A53T α-Synuclein C. elegans Strains to Investigate the Molecular Origins of Parkinson's Disease (2021) (7)
- Quantitative Measurement of the Affinity of Toxic and Nontoxic Misfolded Protein Oligomers for Lipid Bilayers and of its Modulation by Lipid Composition and Trodusquemine (2021) (7)
- Stochastic reconstruction of protein structures from effective connectivity profiles (2008) (7)
- A stochastic method for the reconstruction of protein structures from one-dimensional structural profiles. (2008) (7)
- Spontaneous nucleation and fast aggregate-dependent proliferation of α-synuclein aggregates within liquid condensates at physiological pH (2021) (7)
- New opportunities for tensor-free calculations of residual dipolar couplings for the study of protein dynamics (2014) (7)
- In support of the BMRB (2012) (7)
- Neuroserpin and transthyretin are extracellular chaperones that preferentially inhibit amyloid formation (2021) (7)
- The free energy landscape of the oncogene protein E7 of human papillomavirus type 16 reveals a complex interplay between ordered and disordered regions (2019) (7)
- NMR characterization of the conformational fluctuations of the human lymphocyte function‐associated antigen‐1 I‐domain (2014) (7)
- Multi-scale Bayesian modeling of cryo-electron microscopy density maps (2017) (7)
- Kinetic analysis reveals that independent nucleation events determine the progression of polyglutamine aggregation in C. elegans (2021) (7)
- Cooperative Assembly of Hsp70 Subdomain Clusters (2018) (7)
- Common sequence motifs of nascent chains engage the ribosome surface and trigger factor (2021) (7)
- P525L promotes the aggregation of FUS by altering its biochemical and biophysical properties (2020) (6)
- ARABESQUE: A TOOL FOR PROTEIN STRUCTURAL COMPARISON USING DIFFERENTIAL GEOMETRY AND KNOT THEORY (2012) (6)
- New frontiers for machine learning in protein science. (2021) (6)
- Coarse-grained model for protein folding based on structural profiles. (2011) (6)
- Efficient identification of near‐native conformations in ab initio protein structure prediction using structural profiles (2010) (6)
- Analysis of the performance of the CHESHIRE and YAPP methods at CASD-NMR round 3 (2015) (6)
- Particle-based simulations of steady-state mass transport at high P\'eclet numbers (2015) (6)
- Form of growing strings. (2005) (6)
- The Structurally Constrained Neutral Model of Protein Evolution (2007) (6)
- Distinct responses of human peripheral blood cells to different misfolded protein oligomers (2021) (6)
- Proliferation of Tau 304–380 Fragment Aggregates through Autocatalytic Secondary Nucleation (2021) (6)
- Expression of the amyloid-β peptide in a single pair of C. elegans sensory neurons modulates the associated behavioural response (2019) (6)
- Competition between protein aggregation and protein complex formation (2008) (6)
- An optimal derivation of a potential for protein folding (1999) (6)
- Author Correction: Dynamics of oligomer populations formed during the aggregation of Alzheimer’s Aβ42 peptide (2020) (6)
- Evolution of the missing row deconstruction on Rh (110) (1994) (5)
- Reply to “Comment on ‘A Tensor-Free Method for the Structural and Dynamic Refinement of Proteins using Residual Dipolar Couplings’” (2015) (5)
- Probing the Residual Structure of the Low Populated Denatured State of ADA2h under Folding Conditions by Relaxation Dispersion Nuclear Magnetic Resonance Spectroscopy. (2015) (5)
- Networks in Cell Biology: Introduction (2010) (5)
- Dynamics and Control of Peptide Self-Assembly and Aggregation. (2019) (5)
- Exogenous misfolded protein oligomers can cross the intestinal barrier and cause a disease phenotype in C. elegans (2021) (5)
- Protein dynamics under light control. (2008) (5)
- Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in C. elegans (2018) (5)
- Amyloidogenic proteins in the SARS-CoV and SARS-CoV-2 proteomes (2021) (5)
- Fast fluorescence lifetime imaging reveals the aggregation processes of α-synuclein and polyglutamine in aging Caenorhabditis elegans (2018) (5)
- Assessment of the Quality of Energy Functions for Protein Folding by Using a Criterion Derived With the Help of the Noisy Go Model (2001) (5)
- Determination of the Individual Roles of the Linker Residues in the Inter-Domain Motions of Calmodulin using NMR Chemical Shifts (2014) (5)
- Networks in Cell Biology: Network views of the cell (2010) (4)
- MD Simulations of Intrinsically Disordered Proteins with Replica-Averaged Chemical Shift Restraints (2014) (4)
- In Vivo Translation Rates Can Substantially Delay the Co-Translational Folding of the E. Coli Cytosolic Proteome (2013) (4)
- Erratum: “Molecular dynamics simulations with replica-averaged structural restraints generate structural ensembles according to the maximum entropy principle” [J. Chem. Phys. 138, 094112 (2013)] (2013) (4)
- A method of predicting the in vitro fibril formation propensity of Aβ40 mutants based on their inclusion body levels in E. coli (2019) (4)
- Misfolded protein oligomers induce an increase of intracellular Ca2+ causing an escalation of reactive oxidative species (2022) (4)
- Principles of Protein Structural Ensemble Determination (2018) (4)
- A Practical Guide to the Simultaneous Determination of Protein Structure and Dynamics Using Metainference. (2019) (4)
- A method for partitioning the information contained in a protein sequence between its structure and function (2018) (4)
- The cellular modifier MOAG-4/SERF drives amyloid formation through charge complementation (2020) (4)
- Conformational Entropy as a Potential Liability of Computationally Designed Antibodies (2022) (4)
- Systematic Development of Small Molecules to Inhibit Specific Microscopic Steps of Amyloid-Beta42 Aggregation in Alzheimer's Disease (2018) (4)
- Elusive Unfoldability: Learning a Contact Potential to Fold Crambin (1998) (4)
- Kinetic fingerprints differentiate anti-Aβ therapies (2019) (4)
- π-Clamp-Mediated Homo- and Heterodimerization of Single-Domain Antibodies via Site-Specific Homobifunctional Conjugation (2022) (4)
- Effects of N-terminal acetylation on the aggregation of disease-related α-synuclein variants. (2022) (4)
- Bayesian weighing of electron cryo-microscopy data for integrative structural modeling (2018) (4)
- Environmental Dependence of the Structure of the C-terminal Domain of the SARS-CoV-2 Envelope Protein (2020) (4)
- Detection of non-native hydrophobic interactions in the denatured state of lysozyme by molecular dynamics simulations (2005) (4)
- N-Terminal Acetylation of α-Synuclein Slows down Its Aggregation Process and Alters the Morphology of the Resulting Aggregates (2022) (4)
- Kinetic profiling of therapeutic strategies for inhibiting the formation of amyloid oligomers. (2022) (3)
- Correlation between the binding affinity and the conformational entropy of nanobody SARS-CoV-2 spike protein complexes (2022) (3)
- Two human metabolites rescue a C. elegans model of Alzheimer’s disease via a cytosolic unfolded protein response (2021) (3)
- The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress α-synuclein aggregation (2017) (3)
- A Brain-Permeable Aminosterol Regulates Cell Membranes to Mitigate the Toxicity of Diverse Pore-Forming Agents (2022) (3)
- A maximum caliber approach for continuum path ensembles (2021) (3)
- Vulnerability of the spinal motor neuron presynaptic terminal sub-proteome in ALS (2022) (3)
- A Kinetic Map of the Influence of Biomimetic Lipid Model Membranes on Aβ42 Aggregation (2022) (3)
- Structure-Based Discovery of Small-Molecule Inhibitors of the Autocatalytic Proliferation of α-Synuclein Aggregates (2021) (3)
- Protein stability and foldability–designability complementarity (1998) (3)
- Systematic Development of Small Molecules to Inhibit Specific Steps of α-Synuclein Aggregation in Parkinson's Disease (2018) (3)
- Rationally Designed Bicyclic Peptides Prevent the Conversion of Aβ42 Assemblies Into Fibrillar Structures (2021) (3)
- Sequence-based Prediction of the Cellular Toxicity Associated with Amyloid Aggregation within Protein Condensates (2022) (2)
- Thermodynamic and kinetic design principles for protein aggregation inhibitors (2020) (2)
- 1H, 13C and 15N resonance assignments of human muscle acylphosphatase (2011) (2)
- The RNF 168 paralog RNF 169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage (2017) (2)
- A mistranslation-prone transcriptome underlying polyglutamine expansion diseases (2021) (2)
- Structure and Dynamics o f the Integrin LFA-1 I-Domain in the Inactive State Underlie its Inside-Out / Outside-In Signaling and Allosteric Mechanisms Graphical (2015) (2)
- Vitamin A and vitamin E metabolites comodulate amyloid-β aggregation (2021) (2)
- Identification of a Thyroid Hormone Derivative as a Pleiotropic Agent for the Treatment of Alzheimer’s Disease (2021) (2)
- ATP-competitive inhibitors modulate the substrate binding cooperativity of a kinase by altering its conformational entropy (2022) (2)
- Paratope Prediction using Convolutional and Recurrent Neural Networks (2017) (2)
- Thermodynamics of an Intrinsically Disordered Protein by Atomistic Simulations (2013) (2)
- Bayesian multi-scale modeling of macromolecular structures based on cryo-electron microscopy density maps (2018) (2)
- Excited-state control of protein activity. (2011) (2)
- Protein folding using inter-residue contact (2002) (2)
- The cellular modifier MOAG‐4/SERF drives amyloid formation through charge complementation (2021) (2)
- Computational maturation of a single-domain antibody against Aβ42 aggregation (2021) (2)
- Sequence-based prediction of pH-dependent protein solubility using CamSol (2023) (2)
- Are casein micelles extracellular condensates formed by liquid‐liquid phase separation? (2022) (1)
- Determination of Primary Nucleation Mechanisms of α-Synuclein Amyloid Aggregation (2014) (1)
- Structure and Dynamics of Alzheimer's Associated Amyloid-Beta Peptide (2019) (1)
- Multidimensional Protein Solubility Optimization with an Ultrahigh-Throughput Microfluidic Platform (2022) (1)
- Kinetic analysis reveals the rates and mechanisms of protein aggregation in a multicellular organism (2020) (1)
- An antibody scanning method for the detection of α-synuclein oligomers in the serum of Parkinson's disease patients (2022) (1)
- Attenuating the Toxicity of Amyloid-Beta Aggregation with Specific Species (2017) (1)
- Asymmetric folding pathways and transient misfolding in a coarse-grained model of proteins (2011) (1)
- Factors That Affect the Degree of Twist in beta-Sheet Structures: A Molecular Dynamics Simulation Study of a Cross-beta Filament of the GNNQQNY Peptide (vol 113, pg 1728, 2009) (2009) (1)
- Identification of an RNA Po lymerase III Regulator Linked to Disease-Associated Protein Aggregation Graphical (1)
- A small molecule stabilises the disordered native state of the Alzheimer’s Aβ peptide (2021) (1)
- The codon information index: a quantitative measure of the information provided by the codon bias (2013) (1)
- Microfluidic deposition for resolving single-molecule protein architecture and heterogeneity (2018) (1)
- Sequence-based pH-dependent prediction of protein solubility using CamSol (2022) (1)
- A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers (2021) (1)
- Modulating Amyloid-Beta Aggregation to Reduce the Toxicity of its Oligomeric Aggregates (2018) (1)
- Widespread remodelling of proteome solubility in response to different protein homeostasis stresses (2019) (1)
- Biophysical studies of protein misfolding and aggregation in in vivo models of Alzheimer's and Parkinson's diseases – ERRATUM (2020) (1)
- Determination of a structural ensemble representing the dynamics of a G-quadruplex DNA. (2019) (1)
- Sequence-based prediction and measurement of pH-dependent protein solubility (2022) (1)
- Author response: Structure of a low-population intermediate state in the release of an enzyme product (2014) (1)
- ATOMIC-RESOLUTION STRUCTURE OF A CROSS-BETA QUADRUPLET AMYLOID FIBRIL DETERMINED BY SOLID-STATE MAGIC ANGLE SPINNING NMR AND CRYO-EM (2013) (1)
- Rational Design of Conformation-Specific Antibodies for Tau Oligomers (2020) (1)
- Proteome Metastability in Health, Aging, and Disease (2014) (1)
- Analysis of Sub-tc and Supra-tc Motions in Protein Gb1 Using Molecular Dynamics Simulations (2009) (1)
- A mean-field study of the temperature dependence of the layer magnetizations in a semi-infinite ising model (1993) (1)
- Enhanced surface nanoanalytics of transient biomolecular processes (2022) (1)
- Nanobodies raised against monomeric ɑ-synuclein inhibit fibril formation and destabilize toxic oligomeric species (2017) (1)
- Characterization of Protein Kinase a Free Energy Landscape by NMR-Restrained Metadynamics (2017) (1)
- Author response: The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage (2017) (0)
- Hydrophobicity and unique folding of selected polymers (1998) (0)
- Effects of Amyloid-Beta Expression on Neuronal Signalling Pathways in a Novel C. elegans Model of Alzheimer's Disease (2017) (0)
- A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology (2018) (0)
- Combinations of Vitamin A and Vitamin E Metabolites Confer Resilience against Amyloid-β Aggregation (2023) (0)
- Author Correction: The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress α-synuclein aggregation (2018) (0)
- Proteome-wide prediction of protein solubility (2015) (0)
- Higher-order topological properties (2010) (0)
- Escalating protein supersaturation underlies inclusion formation in muscle proteinopathies (2019) (0)
- 89 Constructing free energy landscapes of RNAs at atomic resolution and characterisation of their excited states (2015) (0)
- Exploration and Exploitation Approaches Based on Generative Machine Learning to Identify Potent Small Molecule Inhibitors of α-Synuclein Secondary Nucleation. (2023) (0)
- Corrigendum (2016) (0)
- On the Effect of the Ribosome and Trigger Factor on Nascent Chain Protein Folding (2011) (0)
- Tau AD fragment aggregates proliferate through autocatalytic secondary nucleation (2021) (0)
- Fast Fluorescence Lifetime Imaging for Longitudinal Studies of Protein Aggregation in Living C. Elegans (2018) (0)
- Systematic mapping of the free energy landscapes of a growing immunoglobulin domain identifies a kinetic intermediate associated with co-translational proline isomerization (2017) (0)
- Developing NMR methods for macromolecular machines: Measurement of residual dipolar couplings to probe dynamic regions of the ribosome (2018) (0)
- Universal lab-on-a-chip microfluidic spray deposition for bulk and single-molecule analytical methods on surfaces (2022) (0)
- Adsorption free energy predicts amyloid protein nucleation rates (2022) (0)
- Sequence‐Based Prediction of Protein Behavior (2013) (0)
- Delivery of Native Proteins into C. elegans Using a Transduction Protocol Based on Lipid Vesicles (2017) (0)
- 0 10 90 42 4 Se p 20 01 Statistical properties of contact vectors (0)
- Modulators of the plasma membrane protect cells from diverse toxic agents, ranging from protein misfolded oligomers to pore forming agents (2022) (0)
- R state structure of monomeric phospholamban (C36A, C41F, C46A) (2013) (0)
- Probing the Interaction of ABETA42 Amyloid Species with an Aggregation Suppressor Molecule by Infrared Nanospectroscopy (2018) (0)
- Unraveling the Physicochemical Determinants of Protein Liquid-liquid Phase Separation by Nanoscale Infrared Vibrational Spectroscopy. (2021) (0)
- Structure of a Misfolded Intermediate of a PDZ Domain (2014) (0)
- Calmodulin complexed with calmodulin-binding peptide from smooth muscle myosin light chain kinase (2008) (0)
- Intermediate state lying on the pathway of release of Tat from HIV-1 TAR. (2016) (0)
- The Royal Society of r and rate-determining steps in fi lamentous self-assembly † (2017) (0)
- New opportunities for tensor-free calculations of residual dipolar couplings for the study of protein dynamics (2014) (0)
- Publisher Correction: Two human metabolites rescue a C. elegans model of Alzheimer’s disease via a cytosolic unfolded protein response (2021) (0)
- Counteraction of amyloid-β aggregation by vitamin A and E metabolites in a crowded environment (2022) (0)
- Straightening the Hierarchical Staircase for Basis Set Extrapolations: A Low-Cost Approach to High-Accuracy Computational Chemistry (2020) (0)
- Aggregation Diseases ndProteostasis to Ameliorate Protein Misfolding a Chemical and Biological Approaches for Adapting (2011) (0)
- Anti-oligomer monoclonal antibodies reveal that protein aggregation modulates generalized physiological and pathological disturbances (2011) (0)
- Native Structure of the Fyn SH3 A39V/N53P/V55L (2012) (0)
- Publisher Correction: A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers (2021) (0)
- 1H, 13C, and 15N chemical shift assignments for alpha-synuclein monomer (WT) (2015) (0)
- A Kinetic Map of the Influence of Biomimetic Lipid Membrane Models on Aβ42 Aggregation (2022) (0)
- Cholesterol rich, highly phase separated, naked mole-rat brain lipids are exquisitely sensitive to amyloid induced membrane damage (2020) (0)
- The amyloid-β pathway in Alzheimer's disease: a plain language summary. (2023) (0)
- FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-p Interactions Graphical Abstract Highlights (2018) (0)
- Erratum: Prediction of variable translation rate effects on cotranslational protein folding (2013) (0)
- Backbone amide assignments for human Cyclophilin C with saturating concentrations of the model peptide GSFGPDLRAGD (2014) (0)
- Folding, Stability and Design of Proteins (1996) (0)
- Therapeutics Against Protein Misfolded Oligomers in Neurodegenerative Diseases (2021) (0)
- A method of predicting the in vitro fibril formation propensity of Aβ40 mutants based on their inclusion body levels in E. coli (2019) (0)
- Insights into the Inhibition Mechanism of Biomolecular Self-Assembly from Chemical Kinetics (2014) (0)
- A metastable subproteome underlies inclusion formation in muscle proteinopathies (2019) (0)
- AlphaFold Prediction of Structural Ensembles of Disordered Proteins (2023) (0)
- Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes (2019) (0)
- Two human metabolites rescue a C. elegans model of Alzheimer’s disease via a cytosolic unfolded protein response (2021) (0)
- A Cell- and Tissue-Specific Weakness of the Protein Homeostasis System Underlies Brain Vulnerability to Protein Aggregation. (2020) (0)
- Ground state sampled during RDC restrained Replica-averaged Metadynamics (RAM) simulations of the HIV-1 TAR complexed with cyclic peptide mimetic of Tat (2016) (0)
- The signal peptide of the amyloid precursor protein forms amyloid-like aggregates and enhances Aβ42 aggregation (2021) (0)
- Lipid membranes from naked mole-rat brain lipids are cholesterol-rich, highly phase-separated, and sensitive to amyloid-induced damage (2020) (0)
- SG-2: A promising lipolytic and pro-autophagic hit-compound to treat Alzheimer’s disease (2020) (0)
- Maturation-Dependent Changes in the Structure and Seeding Capacity of Aβ42 Amyloid Fibrils (2023) (0)
- Proteome-wide analysis of protein stability in E. coli using pulse proteolysis (2019) (0)
- Connectivity of neutral networks and structural conservation in protein evolution (2001) (0)
- Excited state (Bound-like) sampled during RDC restrained Replica-averaged Metadynamics (RAM) simulations of the HIV-1 TAR complexed with cyclic peptide mimetic of Tat (2016) (0)
- Characterization of Pairs of Toxic and Nontoxic Misfolded Protein Oligomers Elucidates the Structural Determinants of Oligomer Toxicity in Protein Misfolding Diseases. (2023) (0)
- A scale-invariant log-normal droplet size distribution below the critical concentration for protein phase separation (2023) (0)
- Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms (2019) (0)
- Growth with Memory Typeset Using Revt E X (2007) (0)
- Publisher Correction: A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers (2021) (0)
- Targeting the Formation of Amyloid Oligomers using Rationally Designed Antibodies (2019) (0)
- Structural investigation of the folding of an immunoglobulin domain on the ribosome using NMR Spectroscopy (LB197) (2014) (0)
- Corrigendum: Structural basis of synaptic vesicle assembly promoted by α-synuclein (2017) (0)
- TARGETING AMYLOID FORMATION USING RATIONALLY DESIGNED ANTIBODIES (2018) (0)
- Structural Investigation of an Immunoglobulin Domain on the Ribosome using NMR Spectroscopy (2017) (0)
- Chemical shift structure of COLICIN E9 DNASE domain with its cognate immunity protein IM9 (2008) (0)
- Modelling the local structure of networks (2010) (0)
- "Life on the Edge": The Relationship Between Cell Abundances and Physical Properties of Proteins (2016) (0)
- Faculty Opinions recommendation of A transient and low-populated protein-folding intermediate at atomic resolution. (2011) (0)
- Atomic-resolution structure of a cross-beta protofilament (2013) (0)
- Flexible anchoring of archaeal MBF1 on ribosomes suggests role as recruitment factor (2014) (0)
- Sequence-based prediction of the solubility of peptides containing non-natural amino acids (2023) (0)
- The Mechanisms of Aberrant Protein Aggregation (2012) (0)
- Varied mechanisms for the neutralization of biological toxins using natural products. (2023) (0)
- Towards a Fully Automated Protein Structure Classiication: How to Get Cath Classiication from Fssp Z-scores (2007) (0)
- ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes (2023) (0)
- Atomic-resolution structure of a triplet cross-beta amyloid fibril (2013) (0)
- Multistep Inhibition of a-synuclein aggregation and toxicity in vitro 1 and in vivo by trodusquemine 2 3 (2019) (0)
- FLN5 (full length) (2019) (0)
- Conformational Equilibrium between the Sub States of the Acidic Denatured State of ACBP Determined by NMR Chemical Shifts and Metadynamics (2014) (0)
- Small molecule and antibody mediated inhibition of the aggregation of a tau fragment implicit in Alzheimer's disease (2022) (0)
- Soluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer’s disease progression (2019) (0)
- Chris Dobson (1949–2019) (2020) (0)
- A single ultrasensitive assay for detection and discrimination of tau aggregates of Alzheimer and Pick diseases (2020) (0)
- EGCG inactivates a pore-forming toxin by promoting its oligomerization and decreasing its solvent-exposed hydrophobicity. (2022) (0)
- Characterization of Free Energy Landscapes of Proteins using NMR Spectroscopy (2013) (0)
- Characterization of full-length p53 aggregates and their kinetics of formation. (2022) (0)
- OP-NARE130962 326..335 (2013) (0)
- Analysis of Sub- t c and Supra- t c Motions in Protein G 1 Using Molecular Dynamics Simulations (2009) (0)
- Thermodynamics and kinetics of protein folding on the ribosome: Alteration in energy landscapes, denatured state, and transition state ensembles (2010) (0)
- Focus on Physical Principles of Protein Behavior in the Cell (2010) (0)
- Structural and Mechanistic Analyses of the Effects of Small Compounds on Amyloid Beta Self-Assembly (2014) (0)
- Trodusquemine displaces protein misfolded oligomers from cell membranes and abrogates their cytotoxicity through a generic mechanism (2020) (0)
- A Machine Learning Approach to Identify Small Molecule Inhibitors of Secondary Nucleation in α-Synuclein Aggregation (2022) (0)
- Determination of structural fluctuations of proteins from structure-based calculations of residual dipolar couplings (2012) (0)
- CELL TYPE–SPECIFIC TAU HOMEOSTASIS SIGNATURES ASSOCIATED WITH SELECTIVE VULNERABILITY OF EXCITATORY NEURONS TO TAU PATHOLOGY (2018) (0)
- Homage to Chris Dobson (2019) (0)
- Therapeutic drug targeting in Alzheimer's disease (2022) (0)
- Phase Separation of FUS is Modulated by Methylation State of Cation-π Interactions and Interaction with TNPO1 (2018) (0)
- Structure-Free Validation of RDC and PRE Measurements of Disordered Proteins (2015) (0)
- ADSoluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer’s disease progression (2019) (0)
- Direct measurement of lipid membrane disruption connects kinetics and toxicity of Aβ42 aggregation (2020) (0)
- Introduction to the special issue of GENE (2008) (0)
- A Machine Learning Approach to Identify Specific Small Molecule Inhibitors of Secondary Nucleation in α-Synuclein Aggregation (2021) (0)
- Rapid and accurate in silico solubility screening of a monoclonal antibody library (2017) (0)
- PLATFORM F: Protein Dynamics - Experiment & Simulation (2011) (0)
- Development of machine learning models for prediction of antibody non-specificity. (2023) (0)
- Publisher Correction: Two human metabolites rescue a C. elegans model of Alzheimer’s disease via a cytosolic unfolded protein response (2021) (0)
- Modeling protein interaction networks (2010) (0)
- Elementary mathematical concepts (2010) (0)
- Oxetane grafts site-selectively installed on native disulfides enhance protein stability and activity in vivo (2017) (0)
- Physical principles of protein behavior in the cell. (2009) (0)
- Elucidating the Structural Basis of α-Synuclein Fibrillation using Small Camelid Nanobodies (2014) (0)
- The free energy landscape of the oncogene protein E7 of human papillomavirus type 16 reveals a complex interplay between ordered and disordered regions (2019) (0)
- Mechanisms of Amyloid-beta 42 oligomer formation from kinetic analysis (2017) (0)
- The aggregation kinetics of α-Synuclein at neutral pH under quiescent conditions (2022) (0)
- 1P079 Mechanism of amyloid formation by beta-lactoglobulin and its relationship with its folding process (2005) (0)
- 1 Dynamic Synaptotagmin-1-SNARE Complex Binding Mode in Solution (2015) (0)
- Networks in Cell Biology: References (2010) (0)
- Polyglutamine Aggregation in a Living Animal is Governed by Biophysical Parameters (2020) (0)
- Extracellular protein homeostasis in neurodegenerative diseases (2023) (0)
- The Zyggregator Method for Predicting Protein Aggregation Propensities (2008) (0)
- Comprar Restrained Simulations of Protein Folding | Michele Vendruscolo | 9781420055092 | Informa Healthcare (2008) (0)
- Determination of the structure and dynamics of the fuzzy coat of an amyloid fibril of IAPP using cryo-electron microscopy (2022) (0)
- The Computational Studies of Co-Translational Protein Folding (2015) (0)
- Chaperone molecules concentrate together with the ubiquitin-proteasome system inside particulate cytoplasmic structures : possible role in metabolism of misfolded proteins (2015) (0)
- Identifying A- and P-site locations on ribosome-protected mRNA fragments using Integer Programming (2019) (0)
- Effects of N-Terminal Acetylation on the Aggregationof Disease-Related a Lpha-Synuclein Variants (2022) (0)
- Chromatin unfolding by epigenetic modifications explained by dramatic impairment of internucleosome interactions : a multiscale study (2017) (0)
- Atomic-resolution structure of a quadruplet cross-beta amyloid fibril (2013) (0)
- FuzPred: a web server for the sequence-based prediction of the context-dependent binding modes of proteins. (2023) (0)
- Atomic-resolution structure of a doublet cross-beta amyloid fibril (2013) (0)
- Single molecule secondary structure determination of proteins through infrared absorption nanospectroscopy (2020) (0)
- Author response: Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in Caenorhabditis elegans (2019) (0)
- Common Regulatory Pathw ays Mediate Activity of MicroRNAs Inducing Cardiomyocyte Proliferation Graphical (2019) (0)
- Folding Intermediate of the Fyn SH3 A39V/N53P/V55L from NMR Relaxation Dispersion Experiments (2011) (0)
- Probing Specificity in Disordered Protein Interactions with Small Molecules using Integrative Methods (2019) (0)
- Growth with memory (1997) (0)
- Analysis of the performance of the CHESHIRE and YAPP methods at CASD-NMR round 3 (2015) (0)
- Amyloid growth: combining experiment and kinetic theory (2012) (0)
- Kinetic analysis of tau aggregation for drug discovery (2022) (0)
- Formation of amyloid loops in brain tissues is controlled by the flexibility of protofibril chains (2022) (0)
- Spontaneous nucleation and fast aggregate-dependent proliferation of α-synuclein aggregates within liquid condensates at neutral pH (2023) (0)
- Author Correction: The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress α-synuclein aggregation (2018) (0)
- Backbone 1H, 13C, and 15N Chemical Shift Assignments for ribosomal protein bL12 S89C and with LBT tag (2019) (0)
- Networks of Dynamic Allo stery Regulate Enzyme Function Highlights (0)
- Methods of probing the interactions between small molecules and disordered proteins (2017) (0)
- 1H and 15N Chemical Shift Assignments for wild-type alpha-synuclein (2018) (0)
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