Mihaela Zavolan
#76,236
Most Influential Person Now
Systems biologist
Mihaela Zavolan's AcademicInfluence.com Rankings
Mihaela Zavolanbiology Degrees
Biology
#3828
World Rank
#5800
Historical Rank
Systems Biology
#20
World Rank
#20
Historical Rank
Bioinformatics
#114
World Rank
#116
Historical Rank
Download Badge
Biology
Mihaela Zavolan's Degrees
- PhD Bioinformatics University of Basel
- Masters Bioinformatics University of Basel
- Bachelors Computer Science University of Bucharest
Similar Degrees You Can Earn
Why Is Mihaela Zavolan Influential?
(Suggest an Edit or Addition)According to Wikipedia, Mihaela Zavolan is a system biologist and Professor at the Biozentrum of the University of Basel. Life Mihaela Zavolan studied medicine at the University of Medicine and Pharmacy in Timișoara, Romania. She then graduated with a PhD in Computer Science from the University of New Mexico in Albuquerque, USA. Between 1993 and 2003 Mihaela Zavolan carried out research in the US, at the Santa Fe Institute in Santa Fe, the Los Alamos National Laboratory in Los Alamos, as well as at the Rockefeller University in New York. In 2003, Mihaela Zavolan was appointed Professor of Computational and Systems Biology at the Biozentrum of the University of Basel. She is also a group leader of the Swiss Institute of Bioinformatics .
Mihaela Zavolan's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing (2007) (3657)
- The Transcriptional Landscape of the Mammalian Genome (2005) (3394)
- Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP (2010) (2685)
- Identification of Virus-Encoded MicroRNAs (2004) (1628)
- Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs (2002) (1543)
- A novel class of small RNAs bind to MILI protein in mouse testes (2006) (1393)
- Identification of microRNAs of the herpesvirus family (2005) (1229)
- The small RNA profile during Drosophila melanogaster development. (2003) (1002)
- MicroRNAs 103 and 107 regulate insulin sensitivity (2011) (904)
- miR-375 maintains normal pancreatic α- and β-cell mass (2009) (697)
- Cell-type-specific signatures of microRNAs on target mRNA expression. (2006) (675)
- Cellular cofactors affecting hepatitis C virus infection and replication (2007) (579)
- Identification and consequences of miRNA–target interactions — beyond repression of gene expression (2014) (548)
- Decay rates of human mRNAs: correlation with functional characteristics and sequence attributes. (2003) (546)
- Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemia. (2007) (507)
- MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells (2008) (502)
- A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins (2011) (453)
- The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line (2009) (441)
- Molecular characterization of human Argonaute-containing ribonucleoprotein complexes and their bound target mRNAs. (2008) (387)
- Inference of miRNA targets using evolutionary conservation and pathway analysis (2007) (362)
- The developmental miRNA profiles of zebrafish as determined by small RNA cloning. (2005) (343)
- Genome-wide analysis of pre-mRNA 3' end processing reveals a decisive role of human cleavage factor I in the regulation of 3' UTR length. (2012) (296)
- Comparative Analysis of mRNA Targets for Human PUF-Family Proteins Suggests Extensive Interaction with the miRNA Regulatory System (2008) (286)
- Analysis of CDS-located miRNA target sites suggests that they can effectively inhibit translation (2013) (283)
- PAR-CliP - A Method to Identify Transcriptome-wide the Binding Sites of RNA Binding Proteins (2010) (278)
- miRNA in situ hybridization in formaldehyde and EDC–fixed tissues (2009) (278)
- Identification of clustered microRNAs using an ab initio prediction method (2005) (268)
- Elevated expression of the miR-17-92 polycistron and miR-21 in hepadnavirus-associated hepatocellular carcinoma contributes to the malignant phenotype. (2008) (261)
- The snoRNA MBII-52 (SNORD 115) is processed into smaller RNAs and regulates alternative splicing. (2010) (261)
- Effects of Dicer and Argonaute down-regulation on mRNA levels in human HEK293 cells (2006) (248)
- MicroRNA Activity Is Suppressed in Mouse Oocytes (2010) (240)
- ISMARA: automated modeling of genomic signals as a democracy of regulatory motifs (2014) (239)
- MicroRNA-7a regulates pancreatic β cell function. (2014) (217)
- Alternative cleavage and polyadenylation in health and disease (2019) (208)
- Impact of alternative initiation, splicing, and termination on the diversity of the mRNA transcripts encoded by the mouse transcriptome. (2003) (208)
- Strand-specific 5'-O-methylation of siRNA duplexes controls guide strand selection and targeting specificity. (2007) (197)
- An updated human snoRNAome (2016) (179)
- Reconstitution of CPSF active in polyadenylation: recognition of the polyadenylation signal by WDR33 (2014) (166)
- A comprehensive analysis of 3′ end sequencing data sets reveals novel polyadenylation signals and the repressive role of heterogeneous ribonucleoprotein C on cleavage and polyadenylation (2015) (162)
- miR-CLIP capture of a miRNA targetome uncovers a lincRNA H19-miR-106a interaction. (2015) (160)
- Patterns of ribosomal protein expression specify normal and malignant human cells (2016) (150)
- A biophysical miRNA-mRNA interaction model infers canonical and noncanonical targets (2013) (149)
- Translation-dependent displacement of UPF1 from coding sequences causes its enrichment in 3′ UTRs (2013) (149)
- Global 3′ UTR shortening has a limited effect on protein abundance in proliferating T cells (2014) (145)
- Deciphering the role of RNA-binding proteins in the post-transcriptional control of gene expression. (2010) (145)
- CLIPZ: a database and analysis environment for experimentally determined binding sites of RNA-binding proteins (2010) (144)
- Virus-encoded microRNAs: novel regulators of gene expression. (2006) (134)
- Argonaute2 Mediates Compensatory Expansion of the Pancreatic β Cell (2014) (133)
- Comparative assessment of methods for the computational inference of transcript isoform abundance from RNA-seq data (2015) (129)
- Insights into snoRNA biogenesis and processing from PAR-CLIP of snoRNA core proteins and small RNA sequencing (2013) (124)
- Kaposi's Sarcoma Herpesvirus microRNAs Target Caspase 3 and Regulate Apoptosis (2011) (114)
- Protein synthesis rates and ribosome occupancies reveal determinants of translation elongation rates (2018) (112)
- Marek's Disease Virus Type 2 (MDV-2)-Encoded MicroRNAs Show No Sequence Conservation with Those Encoded by MDV-1 (2007) (110)
- Widespread context dependency of microRNA-mediated regulation (2014) (107)
- Relative contribution of sequence and structure features to the mRNA binding of Argonaute/EIF2C-miRNA complexes and the degradation of miRNA targets. (2009) (106)
- Systematic characterization of the zinc-finger-containing proteins in the mouse transcriptome. (2003) (104)
- PolyASite 2.0: a consolidated atlas of polyadenylation sites from 3′ end sequencing (2019) (99)
- PAR-CLIP (Photoactivatable Ribonucleoside-Enhanced Crosslinking and Immunoprecipitation): a step-by-step protocol to the transcriptome-wide identification of binding sites of RNA-binding proteins. (2014) (98)
- Roquin Suppresses the PI3K‐mTOR Signaling Pathway to Inhibit T Helper Cell Differentiation and Conversion of Treg to Tfr Cells (2017) (96)
- Expression and Processing of a Small Nucleolar RNA from the Epstein-Barr Virus Genome (2009) (91)
- MirZ: an integrated microRNA expression atlas and target prediction resource (2009) (91)
- Identification and consequences of miRNA–target interactions — beyond repression of gene expression (2014) (82)
- CLIP and complementary methods (2021) (80)
- A Simple Physical Model Predicts Small Exon Length Variations (2006) (79)
- Splice variation in mouse full-length cDNAs identified by mapping to the mouse genome. (2002) (78)
- Computational analysis of small RNA cloning data. (2008) (78)
- Means to an end: mechanisms of alternative polyadenylation of messenger RNA precursors (2013) (75)
- PAPD5, a noncanonical poly(A) polymerase with an unusual RNA-binding motif. (2011) (75)
- Expression proteomics of UPF1 knockdown in HeLa cells reveals autoregulation of hnRNP A2/B1 mediated by alternative splicing resulting in nonsense-mediated mRNA decay (2010) (74)
- Probabilistic clustering of sequences: Inferring new bacterial regulons by comparative genomics (2002) (72)
- TUT‐DIS3L2 is a mammalian surveillance pathway for aberrant structured non‐coding RNAs (2016) (71)
- The neuromuscular junction is a focal point of mTORC1 signaling in sarcopenia (2020) (68)
- Analysis of the Genetic Variability of Virulence-Related Loci in Epidemic Clones of Methicillin-Resistant Staphylococcus aureus (2005) (67)
- The Gcn4 transcription factor reduces protein synthesis capacity and extends yeast lifespan (2017) (64)
- MicroRNA‐194 is a target of transcription factor 1 (Tcf1, HNF1α) in adult liver and controls expression of frizzled‐6 (2012) (60)
- Analysis of in situ pre-mRNA targets of human splicing factor SF1 reveals a function in alternative splicing (2010) (57)
- Timescales and bottlenecks in miRNA-dependent gene regulation (2013) (55)
- miR-184 Regulates Pancreatic β-Cell Function According to Glucose Metabolism* (2015) (52)
- Genome-wide Analysis of Pre-mRNA 3 0 End Processing Reveals a Decisive Role of Human Cleavage Factor I in the Regulation of 3 0 UTR Length (2012) (50)
- Discovery of physiological and cancer-related regulators of 3′ UTR processing with KAPAC (2018) (43)
- Argonaute CLIP--a method to identify in vivo targets of miRNAs. (2012) (42)
- High-throughput identification of C/D box snoRNA targets with CLIP and RiboMeth-seq (2016) (41)
- Modulation of epigenetic regulators and cell fate decisions by miRNAs. (2013) (41)
- Roquin recognizes a non-canonical hexaloop structure in the 3′-UTR of Ox40 (2016) (40)
- Accurate transcriptome-wide prediction of microRNA targets and small interfering RNA off-targets with MIRZA-G (2015) (39)
- SPA: A Probabilistic Algorithm for Spliced Alignment (2006) (36)
- Roquin targets mRNAs in a 3′-UTR-specific manner by different modes of regulation (2018) (36)
- Bayesian inference of gene expression states from single-cell RNA-seq data (2021) (35)
- The Alazami Syndrome-Associated Protein LARP7 Guides U6 Small Nuclear RNA Modification and Contributes to Splicing Robustness. (2020) (33)
- Embryonic stem cell-specific microRNAs contribute to pluripotency by inhibiting regulators of multiple differentiation pathways (2014) (33)
- Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis (2020) (33)
- The types and prevalence of alternative splice forms. (2006) (32)
- Accurate transcriptome-wide prediction of microRNA targets and small interfering RNA off-targets with MIRZA-G (2015) (32)
- A rare codon-based translational program of cell proliferation (2020) (32)
- TSSer: an automated method to identify transcription start sites in prokaryotic genomes from differential RNA sequencing data (2014) (28)
- Statistical inference of sequence-dependent mutation rates. (2001) (28)
- Modeling the binding specificity of the RNA-binding protein GLD-1 suggests a function of coding region–located sites in translational repression (2013) (27)
- miRNA in situ hybridization in mammalian tissues fixed with formaldehyde and EDC (2009) (27)
- Molecular and phenotypic analysis of rodent models reveals conserved and species-specific modulators of human sarcopenia (2021) (26)
- Inference of miRNA targets using evolutionary conservation and pathway analysis (2007) (23)
- TFAP2A is a component of the ZEB1/2 network that regulates TGFB1-induced epithelial to mesenchymal transition (2017) (23)
- Structure of SRSF1 RRM1 bound to RNA reveals an unexpected bimodal mode of interaction and explains its involvement in SMN1 exon7 splicing (2021) (22)
- Quantifying the strength of miRNA-target interactions. (2015) (22)
- Regulation of human liver δ‐aminolevulinic acid synthase by bile acids (2007) (21)
- Nanopore sequencing reveals endogenous NMD-targeted isoforms in human cells (2021) (20)
- Cooperative target mRNA destabilization and translation inhibition by miR-58 microRNA family in C. elegans (2015) (20)
- Single‐cell mRNA profiling reveals the hierarchical response of miRNA targets to miRNA induction (2018) (20)
- Explicit Modeling of siRNA-Dependent On- and Off-Target Repression Improves the Interpretation of Screening Results. (2017) (19)
- SMASHing regulatory sites in DNA by human-mouse sequence comparisons (2003) (19)
- Seq and CLIP through the miRNA world (2014) (19)
- Terminal exon characterization with TECtool reveals an abundance of cell-specific isoforms (2018) (19)
- Prevention of dsRNA‐induced interferon signaling by AGO1x is linked to breast cancer cell proliferation (2020) (17)
- Conserved generation of short products at piRNA loci (2011) (17)
- Analysis of Human Immunodeficiency Virus Cytopathicity by Using a New Method for Quantitating Viral Dynamics in Cell Culture (2005) (17)
- Distinct and additive effects of calorie restriction and rapamycin in aging skeletal muscle (2022) (15)
- Regulation of human liver delta-aminolevulinic acid synthase by bile acids. (2007) (13)
- Structural and functional implications of the QUA2 domain on RNA recognition by GLD-1 (2014) (13)
- Fifteen years SIB Swiss Institute of Bioinformatics: life science databases, tools and support (2014) (13)
- MicroRNA-7 a regulates pancreatic beta cell function (2017) (12)
- Cooperative target mRNA destabilization and translation inhibition by miR-58 microRNA family inC (2017) (11)
- Automated incorporation of pairwise dependency in transcription factor binding site prediction using dinucleotide weight tensors (2016) (10)
- Bayesian inference of the gene expression states of single cells from scRNA-seq data (2019) (10)
- Computational Analysis of Full-length cDNAs Reveals Frequent Coupling Between Transcriptional and Splicing Programs (2008) (9)
- 3'-UTR poly(T/U) tract deletions and altered expression of EWSR1 are a hallmark of mismatch repair-deficient cancers. (2014) (8)
- RNA splicing and its connection with other regulatory layers in somatic cell reprogramming. (2018) (8)
- Transcriptional Enhancer Factor Domain Family member 4 Exerts an Oncogenic Role in Hepatocellular Carcinoma by Hippo‐Independent Regulation of Heat Shock Protein 70 Family Members (2021) (8)
- 3' End Sequencing Library Preparation with A-seq2 (2017) (7)
- Loss of TSC complex enhances gluconeogenesis via upregulation of Dlk1-Dio3 locus miRNAs (2020) (6)
- Redesigning CLIP for efficiency, accuracy and speed (2016) (6)
- Shortening of 3′ UTRs in most cell types composing tumor tissues implicates alternative polyadenylation in protein metabolism (2021) (5)
- Gene Expression Signatures of a Preclinical Mouse Model during Colorectal Cancer Progression under Low-Dose Metronomic Chemotherapy (2020) (5)
- MINA-1 and WAGO-4 are part of regulatory network coordinating germ cell death and RNAi in C. elegans (2019) (4)
- Untargeted sequencing of circulating microRNAs in a healthy and diseased older population (2022) (3)
- Conserved regulation of RNA processing in somatic cell reprogramming (2019) (3)
- Dual roles of mTORC1-dependent activation of the ubiquitin-proteasome system in muscle proteostasis (2021) (3)
- Dicer partners expand the repertoire of miRNA targets (2012) (3)
- Transcriptome‐Wide Identification of Protein Binding Sites on RNA by PAR‐CLIP (Photoactivatable‐Ribonucleoside‐Enhanced Crosslinking and Immunoprecipitation) (2014) (3)
- CFIm-mediated alternative polyadenylation remodels cellular signaling and miRNA biogenesis (2022) (2)
- ISMARA: Completely automated inference of gene regulatory networks from high-throughput data (2017) (2)
- Corrigendum to "Quantifying the strength of miRNA-target interactions" [Methods (2015) 90-99]. (2016) (2)
- Frequent co-regulation of splicing and polyadenylation by RNA-binding proteins inferred with MAPP (2022) (2)
- Characterization and Prediction of miRNA Targets (2014) (2)
- of regulatory motifs ISMARA : automated modeling of genomic signals as a democracy Material Supplemental (2014) (2)
- Inferring gene expression regulatory networks from high-throughput measurements. (2015) (2)
- Author Correction: Distinct and additive effects of calorie restriction and rapamycin in aging skeletal muscle (2021) (2)
- Report MicroRNA Activity Is Suppressed in Mouse Oocytes (2010) (2)
- Improved analysis of (e)CLIP data with RCRUNCH yields a compendium of RNA-binding protein binding sites and motifs (2023) (2)
- AGO1x prevents dsRNA-induced interferon signaling to promote breast cancer cell proliferation (2019) (2)
- Authors' Reply (2006) (2)
- Ewing sarcoma breakpoint region 1 prevents transcription-associated genome instability (2015) (2)
- The 3′ UTR Landscape in Cancer (2018) (2)
- Molecular and phenotypic analysis of rodent models reveals conserved and species-specific modulators of human sarcopenia (2021) (1)
- ZARP: An automated workflow for processing of RNA-seq data (2021) (1)
- A novel approach to single‐cell analysis reveals intrinsic differences in immune marker expression in unstimulated BALB/c and C57BL/6 macrophages (2022) (1)
- Supporting Material Response to : Alternative splicing at NAGNAG acceptors : Simply noise or noise and more ? (2006) (1)
- Exploiting variability of single cells to uncover the in vivo hierarchy of miRNA targets (2015) (1)
- Conserved regulation of RNA processing in somatic cell reprogramming (2019) (1)
- Dicer partners expand the repertoire of miRNA targets (2012) (1)
- Nanopore sequencing reveals endogenous NMD-targeted isoforms in human cells (2021) (1)
- PUM targets encode proteins acting in cancer related pathways. (2008) (1)
- A rare codon-based translational program of cell proliferation (2020) (1)
- SMASHing regulatory sites in DNA by human. (2003) (1)
- Seq and CLIP through the miRNA world (2014) (1)
- Biophysical Analysis of miRNA-Dependent Gene Regulation (2018) (1)
- Molecular and Cellular Pathobiology 3 0-UTR Poly ( T / U ) Tract Deletions and Altered Expression of EWSR 1 Are a Hallmark of Mismatch Repair – De fi cient Cancers (2013) (0)
- Transcription factor motif activity as a biomarker of muscle aging (2021) (0)
- Explorer Trends and challenges in Computational RNA biology (2016) (0)
- Transcriptome‐wide Identification of the mRNA target sites of the Fragile‐X Mental Retardation Proteins (2009) (0)
- Cholesterol deprivation drives DHEA biosynthesis in human adrenals. (2022) (0)
- The transcriptional landscape of a hepatoma cell line grown on scaffolds of extracellular matrix proteins (2020) (0)
- The transcriptional landscape of a hepatoma cell line grown on scaffolds of extracellular matrix proteins (2021) (0)
- Discovery of global regulators of 3′ untranslated region processing in cancers with KAPAC (2017) (0)
- Ribosomal protein RPL39L is an efficiency factor in the cotranslational folding of proteins with alpha helical domains (2023) (0)
- Mirroring the multifaceted role of RNA and its partners in gene expression (2018) (0)
- Deciphering the regulatory functions of miRNAs (2014) (0)
- The Gcn4 transcription factor reduces protein synthesis capacity and extends yeast lifespan (2017) (0)
- MINA-1 and WAGO-4 are part of regulatory network coordinating germ cell death and RNAi in C. elegans (2019) (0)
- Discovery of physiological and cancer-related regulators of 3′ UTR processing with KAPAC (2017) (0)
- Ligation of Reverse 3 ' Adapters to the 5 ' End of RNA Fragments (2017) (0)
- ZARP: Automated processing of RNA-seq data (2020) (0)
- Patterns of ribosomal protein expression specify normal and malignant human cells (2016) (0)
- P1303 clfB typing in Staphylococcus aureus: online database for dis-play, clustering analysis and storage of clfB DNA sequences (2007) (0)
- Abstract 1910: 3′UTR poly(T/U) tract deletions and altered expression ofEWSR1are a hallmark of mismatch repair-deficient cancers. (2013) (0)
- Former and present aspects in neuro-skull architecture. (2006) (0)
- The Contribution of Alternative Transcription and Alternative Splicing to the Complexity of Mammalian Transcriptomes (2006) (0)
- TFAP2A is a component of the ZEB1/2 network that regulates TGFB1-induced epithelial to mesenchymal transition (2017) (0)
- Comparative Genomics Methods for the Prediction of Small RNA‐Binding Sites (2012) (0)
- Structure of SRSF1 RRM1 bound to RNA reveals an unexpected bimodal mode of interaction and explains its involvement in SMN1 exon7 splicing (2021) (0)
- A novel approach to single cell analysis to reveal intrinsic differences in immune marker expression in unstimulated macrophages from BALB/c and C57BL/6 mouse strains (2022) (0)
- Abstract 3802: EWSR1: Identification and functional characterization of a novel target gene locus in Lynch syndrome (2011) (0)
- Reply to ‘A different perspective on alternative cleavage and polyadenylation’ (2019) (0)
- RNAs: dynamic and mutable (2017) (0)
- miRNA Profiling of Pediatric ALL and Non-Hodgkin Lymphomas. (2005) (0)
- Terminal exon characterization with TECtool reveals an abundance of cell-specific isoforms (2018) (0)
- T helper cells exhibit a dynamic and reversible 3’UTR landscape (2023) (0)
- Reflections on the RNA world (2015) (0)
- Comparative assessment of methods for the computational inference of transcript isoform abundance from RNA-seq data (2015) (0)
- Insights into snoRNA biogenesis and processing from PAR-CLIP of snoRNA core proteins and small RNA sequencing (2013) (0)
- 3 0 -UTR Poly(T/U) Tract Deletions and Altered Expression of EWSR1 Are a Hallmark of Mismatch Repair – De fi cient Cancers (2013) (0)
- Mechanisms of small RNA mediated mammalian gene silencing (2007) (0)
- Reply to ‘A different perspective on alternative cleavage and polyadenylation’ (2019) (0)
- Computational Biology of Small Regulatory RNAs (2009) (0)
- Deciphering the landscape of snoRNA-mediated RNA modifications with high-throughput sequencing approaches (2017) (0)
- In memoriam: Francisc Schneider (1933‐2017) (2019) (0)
- Roquin targets mRNAs in a 3′-UTR-specific manner by different modes of regulation (2018) (0)
- ribonucleoprotein complexes and their bound target mRNAs Molecular characterization of human Argonaute-containing Material Supplemental (0)
- WES-ELIXIR: A Language-Agnostic Execution Service for Bioinformatics Workflows (2019) (0)
- RNAs: dynamic and mutable (2017) (0)
- small RNA cloning The developmental miRNA profiles of zebrafish as determined by Material Supplemental (2005) (0)
This paper list is powered by the following services:
Other Resources About Mihaela Zavolan
What Schools Are Affiliated With Mihaela Zavolan?
Mihaela Zavolan is affiliated with the following schools:
