Mihai Netea
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Mihai Neteabiology Degrees
Biology
#1974
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#3184
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Immunology
#66
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#72
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Biochemistry
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#220
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Biology
Mihai Netea's Degrees
- PhD Immunology Radboud University Nijmegen
Why Is Mihai Netea Influential?
(Suggest an Edit or Addition)According to Wikipedia, Mihai G. Netea is a Romanian Dutch physician and professor at Radboud University Nijmegen, specialized in infectious disease, immunology, and global health. Netea studied medicine at the Medico-Pharmaceutical Institute in Cluj-Napoca. He received a doctoral degree in 1998 at Radboud University, with a dissertation on the role of cytokines in sepsis, written under the direction of Jos van der Meer.
Mihai Netea's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Hidden Killers: Human Fungal Infections (2012) (2990)
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (2012) (2913)
- Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure (2020) (1617)
- Trained immunity: A program of innate immune memory in health and disease (2016) (1587)
- mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity (2014) (1314)
- The Human Cell Atlas (2017) (1285)
- Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity (2016) (1208)
- Bacille Calmette-Guérin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes (2012) (1162)
- Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity (2014) (1154)
- Trained immunity: a memory for innate host defense. (2011) (1043)
- Defining trained immunity and its role in health and disease (2020) (965)
- A minimal common outcome measure set for COVID-19 clinical research (2020) (939)
- The immunopathology of sepsis and potential therapeutic targets (2017) (920)
- An integrated model of the recognition of Candida albicans by the innate immune system (2008) (885)
- Candida albicans infection affords protection against reinfection via functional reprogramming of monocytes. (2012) (828)
- Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 (2021) (811)
- Toll-like receptor 2 controls expansion and function of regulatory T cells. (2006) (805)
- Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages. (2009) (765)
- BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity. (2018) (742)
- Candida albicans morphogenesis and host defence: discriminating invasion from colonization (2011) (710)
- Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors. (2006) (700)
- Human dectin-1 deficiency and mucocutaneous fungal infections. (2009) (698)
- Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity (2016) (638)
- Toll-Like Receptor 2 Suppresses Immunity against Candida albicans through Induction of IL-10 and Regulatory T Cells (2004) (634)
- Inflammasome activation and IL-1β and IL-18 processing during infection. (2011) (604)
- Inflammasome is a central player in the induction of obesity and insulin resistance (2011) (602)
- Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming (2018) (597)
- STAT1 mutations in autosomal dominant chronic mucocutaneous candidiasis. (2011) (584)
- Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity (2018) (568)
- The effect of host genetics on the gut microbiome (2016) (566)
- Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases (2019) (553)
- The role of TNF-alpha in chronic inflammatory conditions, intermediary metabolism, and cardiovascular risk. (2007) (540)
- Presence of Genetic Variants Among Young Men With Severe COVID-19. (2020) (530)
- The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity. (2010) (488)
- Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity. (2016) (483)
- The role of toll-like receptor (TLR) 2 and TLR4 in the host defense against disseminated candidiasis. (2002) (472)
- IL-1β Processing in Host Defense: Beyond the Inflammasomes (2010) (471)
- Long-Lasting Effects of BCG Vaccination on Both Heterologous Th1/Th17 Responses and Innate Trained Immunity (2013) (440)
- Innate Immune Recognition of Mycobacterium tuberculosis (2011) (418)
- A small jab - a big effect: nonspecific immunomodulation by vaccines. (2013) (415)
- Oxidized Low-Density Lipoprotein Induces Long-Term Proinflammatory Cytokine Production and Foam Cell Formation via Epigenetic Reprogramming of Monocytes (2014) (411)
- Metabolic Induction of Trained Immunity through the Mevalonate Pathway (2018) (404)
- A guiding map for inflammation (2017) (402)
- Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis (2016) (395)
- Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance (2006) (382)
- The C‐type lectin DC‐SIGN (CD209) is an antigen‐uptake receptor for Candida albicans on dendritic cells (2003) (378)
- Immunometabolic Pathways in BCG-Induced Trained Immunity (2016) (377)
- Genomewide association study of leprosy. (2010) (375)
- Immune defence against Candida fungal infections (2015) (371)
- NOD2 and Toll-Like Receptors Are Nonredundant Recognition Systems of Mycobacterium tuberculosis (2005) (369)
- BCG-induced trained immunity: can it offer protection against COVID-19? (2020) (369)
- β-Glucan Reverses the Epigenetic State of LPS-Induced Immunological Tolerance (2016) (368)
- Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors (2008) (365)
- The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery (2016) (360)
- Host and Environmental Factors Influencing Individual Human Cytokine Responses (2016) (341)
- Trained Immunity: a Tool for Reducing Susceptibility to and the Severity of SARS-CoV-2 Infection (2020) (338)
- Dectin‐1 synergizes with TLR2 and TLR4 for cytokine production in human primary monocytes and macrophages (2008) (336)
- IL-32, a proinflammatory cytokine in rheumatoid arthritis. (2006) (335)
- Genetic variation in Toll-like receptors and disease susceptibility (2012) (332)
- The macrophage mannose receptor induces IL-17 in response to Candida albicans. (2009) (330)
- Non-specific effects of BCG vaccine on viral infections. (2019) (326)
- Oxidized Phospholipids on Lipoprotein(a) Elicit Arterial Wall Inflammation and an Inflammatory Monocyte Response in Humans (2016) (316)
- Derived immune and ancestral pigmentation alleles in a 7,000-year-old Mesolithic European (2014) (314)
- BCG-induced trained immunity in NK cells: Role for non-specific protection to infection. (2014) (314)
- TLR4 polymorphisms, infectious diseases, and evolutionary pressure during migration of modern humans (2007) (312)
- Inhibition of Toll-like receptor 4 breaks the inflammatory loop in autoimmune destructive arthritis. (2007) (309)
- Circulating cytokines as mediators of fever. (2000) (307)
- Aspergillus fumigatus evades immune recognition during germination through loss of toll-like receptor-4-mediated signal transduction. (2003) (306)
- Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta. (2009) (304)
- IL-1 family nomenclature (2010) (302)
- Toll‐like receptors and the host defense against microbial pathogens: bringing specificity to the innate‐immune system (2004) (296)
- Does the shape of lipid A determine the interaction of LPS with Toll-like receptors? (2002) (292)
- IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist (2012) (291)
- IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism. (2005) (290)
- Aspergillus fumigatus morphology and dynamic host interactions (2017) (288)
- Nucleotide-Binding Oligomerization Domain-2 Modulates Specific TLR Pathways for the Induction of Cytokine Release 1 (2005) (284)
- Inflammasome-independent regulation of IL-1-family cytokines. (2015) (281)
- Considering BCG vaccination to reduce the impact of COVID-19 (2020) (273)
- Modulation of inflammation by autophagy: Consequences for human disease (2015) (273)
- The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity (2021) (264)
- Immune Recognition of Candida albicans β-glucan by Dectin-1 (2007) (262)
- IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans (2014) (262)
- Engagement of fatty acids with Toll-like receptor 2 drives interleukin-1β production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis. (2010) (258)
- Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial (2021) (255)
- The inflammasome puts obesity in the danger zone. (2012) (251)
- Functional Consequences of Toll-like Receptor 4 Polymorphisms (2008) (249)
- Early stop polymorphism in human DECTIN-1 is associated with increased candida colonization in hematopoietic stem cell transplant recipients. (2009) (243)
- A Functional Genomics Approach to Understand Variation in Cytokine Production in Humans (2016) (238)
- NOD2 mediates anti‐inflammatory signals induced by TLR2 ligands: implications for Crohn's disease (2004) (237)
- Innate and Adaptive Immune Memory: an Evolutionary Continuum in the Host's Response to Pathogens. (2019) (235)
- TNFR2 Is Critical for the Stabilization of the CD4+Foxp3+ Regulatory T Cell Phenotype in the Inflammatory Environment (2013) (234)
- Human TLR10 is an anti-inflammatory pattern-recognition receptor (2014) (234)
- Interplay between Candida albicans and the Mammalian Innate Host Defense (2012) (231)
- Neutralization of IL-18 Reduces Neutrophil Tissue Accumulation and Protects Mice Against Lethal Escherichia coli and Salmonella typhimurium Endotoxemia1 (2000) (229)
- Trained Immunity or Tolerance: Opposing Functional Programs Induced in Human Monocytes after Engagement of Various Pattern Recognition Receptors (2014) (227)
- Influence of anti-tumour necrosis factor therapy on cardiovascular risk factors in patients with active rheumatoid arthritis (2004) (224)
- Swarm Learning for decentralized and confidential clinical machine learning (2021) (224)
- Reactive oxygen species–independent activation of the IL-1β inflammasome in cells from patients with chronic granulomatous disease (2010) (223)
- Activate: Randomized Clinical Trial of BCG Vaccination against Infection in the Elderly (2020) (223)
- Therapeutic targeting of trained immunity (2019) (221)
- IL-1β/IL-6/CRP and IL-18/ferritin: Distinct Inflammatory Programs in Infections (2016) (218)
- Dendritic Cell Interaction with Candida albicans Critically Depends on N-Linked Mannan* (2008) (218)
- A Crohn's disease–associated NOD2 mutation suppresses transcription of human IL10 by inhibiting activity of the nuclear ribonucleoprotein hnRNP-A1 (2009) (215)
- Fungal Chitin Dampens Inflammation through IL-10 Induction Mediated by NOD2 and TLR9 Activation (2014) (213)
- Oxidized LDL enhances pro-inflammatory responses of alternatively activated M2 macrophages: a crucial role for Krüppel-like factor 2. (2011) (212)
- Kallikrein-kinin blockade in patients with COVID-19 to prevent acute respiratory distress syndrome (2020) (211)
- Favorable Anakinra Responses in Severe Covid-19 Patients with Secondary Hemophagocytic Lymphohistiocytosis (2020) (210)
- Toll-like receptors on regulatory T cells: expanding immune regulation. (2006) (209)
- Immunotherapy for the adjunctive treatment of sepsis: from immunosuppression to immunostimulation. Time for a paradigm change? (2013) (208)
- Microbial stimulation of different Toll-like receptor signalling pathways induces diverse metabolic programmes in human monocytes (2016) (208)
- Listeria monocytogenes-Infected Human Peripheral Blood Mononuclear Cells Produce IL-1β, Depending on Listeriolysin O and NLRP3 (2009) (203)
- Low-density lipoprotein receptor-deficient mice are protected against lethal endotoxemia and severe gram-negative infections. (1996) (203)
- Apolipoprotein E knock-out mice are highly susceptible to endotoxemia and Klebsiella pneumoniae infection. (1999) (201)
- Proinflammatory cytokines and sepsis syndrome: not enough, or too much of a good thing? (2003) (201)
- Innate immune memory: towards a better understanding of host defense mechanisms. (2014) (199)
- In Vitro Experimental Model of Trained Innate Immunity in Human Primary Monocytes (2016) (198)
- Differential Cytokine Production and Toll-Like Receptor Signaling Pathways by Candida albicans Blastoconidia and Hyphae (2005) (197)
- Recognition of fungal pathogens by Toll-like receptors (2004) (197)
- Innate immune memory: a paradigm shift in understanding host defense (2015) (196)
- The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity. (2019) (195)
- Mycobacterium tuberculosis Induces Interleukin-32 Production through a Caspase- 1/IL-18/Interferon-γ-Dependent Mechanism (2006) (192)
- From the Th1/Th2 Paradigm towards a Toll-Like Receptor/T-Helper Bias (2005) (192)
- Reversal of immunoparalysis in humans in vivo: a double-blind, placebo-controlled, randomized pilot study. (2012) (192)
- Safety and Efficacy of Anakinra in Severe Hidradenitis Suppurativa: A Randomized Clinical Trial. (2016) (190)
- Harnessing the beneficial heterologous effects of vaccination (2016) (186)
- Interferon-gamma as adjunctive immunotherapy for invasive fungal infections: a case series (2014) (186)
- BCG Vaccination Enhances the Immunogenicity of Subsequent Influenza Vaccination in Healthy Volunteers: A Randomized, Placebo-Controlled Pilot Study. (2015) (185)
- Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity (2020) (185)
- The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans (2011) (185)
- Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2 (2011) (184)
- IL-37 protects against obesity-induced inflammation and insulin resistance (2014) (184)
- Inflammasome-Independent Modulation of Cytokine Response by Autophagy in Human Cells (2011) (181)
- Trained Immunity: An Ancient Way of Remembering. (2017) (180)
- Metabolic changes in tumor cells and tumor-associated macrophages: A mutual relationship. (2018) (179)
- BCG Vaccination in Humans Elicits Trained Immunity via the Hematopoietic Progenitor Compartment (2020) (179)
- CX3CR1-dependent renal macrophage survival promotes Candida control and host survival. (2013) (178)
- Regulation of cytokine responses by seasonality of vitamin D status in healthy individuals (2011) (178)
- TREM‐1: intracellular signaling pathways and interaction with pattern recognition receptors (2013) (177)
- Gut microbiome in ADHD and its relation to neural reward anticipation (2017) (177)
- Gender differences in the innate immune response and vascular reactivity following the administration of endotoxin to human volunteers* (2007) (176)
- Metabolism impacts upon Candida immunogenicity and pathogenicity at multiple levels (2014) (175)
- Autophagy activity is up-regulated in adipose tissue of obese individuals and modulates proinflammatory cytokine expression. (2012) (175)
- Recognition and Blocking of Innate Immunity Cells by Candida albicans Chitin (2011) (175)
- Soluble uric acid primes TLR-induced proinflammatory cytokine production by human primary cells via inhibition of IL-1Ra (2015) (175)
- Markers of inflammation are negatively correlated with serum leptin in rheumatoid arthritis (2005) (175)
- Toll-like receptors as an escape mechanism from the host defense. (2004) (173)
- The anti-CD20 antibody rituximab reduces the Th17 cell response. (2011) (172)
- Inherited CARD9 deficiency in otherwise healthy children and adults with Candida species-induced meningoencephalitis, colitis, or both. (2015) (171)
- Immune recognition of Candida albicans beta-glucan by dectin-1. (2007) (169)
- Trained immunity, tolerance, priming and differentiation: distinct immunological processes (2020) (168)
- Trained innate immunity as underlying mechanism for the long‐term, nonspecific effects of vaccines (2015) (166)
- Evolutionary and functional analysis of celiac risk loci reveals SH2B3 as a protective factor against bacterial infection. (2010) (166)
- Aspergillus Cell Wall Melanin Blocks LC3-Associated Phagocytosis to Promote Pathogenicity. (2016) (166)
- Successful Treatment of Dermatomyositis and Polymyositis with Anti-Tumor-Necrosis-Factor-Alpha: Preliminary Observations (2003) (165)
- Increased susceptibility of TNF-alpha lymphotoxin-alpha double knockout mice to systemic candidiasis through impaired recruitment of neutrophils and phagocytosis of Candida albicans. (1999) (165)
- Toll-like receptor 4 Asp299Gly/Thr399Ile polymorphisms are a risk factor for Candida bloodstream infection. (2006) (164)
- Modulation of lipoprotein plasma concentrations during long-term anti-TNF therapy in patients with active rheumatoid arthritis (2007) (163)
- Differential Adaptation of Candida albicans In Vivo Modulates Immune Recognition by Dectin-1 (2013) (163)
- Prevalence of xenotropic murine leukaemia virus-related virus in patients with chronic fatigue syndrome in the Netherlands: retrospective analysis of samples from an established cohort (2010) (163)
- Inflammation links excess fat to insulin resistance: the role of the interleukin‐1 family (2012) (161)
- Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans (2013) (160)
- Interleukin-32 induces the differentiation of monocytes into macrophage-like cells (2008) (160)
- The role of hyperuricemia in the increased cytokine production after lipopolysaccharide challenge in neutropenic mice. (1997) (158)
- Hyperglycemia Activates Caspase-1 and TXNIP-Mediated IL-1β Transcription in Human Adipose Tissue (2011) (158)
- IFN-γ-Stimulated Neutrophils Suppress Lymphocyte Proliferation through Expression of PD-L1 (2013) (158)
- Host-microbe interactions: innate pattern recognition of fungal pathogens. (2008) (157)
- Non-specific effects of vaccines: Current evidence and potential implications. (2018) (156)
- Epigenetics and Trained Immunity. (2017) (154)
- DNA methylation in childhood asthma: an epigenome-wide meta-analysis. (2018) (153)
- Population genomics of Mesolithic Scandinavia: Investigating early postglacial migration routes and high-latitude adaptation (2018) (153)
- Training innate immunity: the changing concept of immunological memory in innate host defence (2013) (152)
- The Cellular and Molecular Basis of Translational Immunometabolism. (2015) (152)
- Heterologous Immunological Effects of Early BCG Vaccination in Low-Birth-Weight Infants in Guinea-Bissau: A Randomized-controlled Trial (2014) (151)
- Treatment with Anakinra improves disposition index but not insulin sensitivity in nondiabetic subjects with the metabolic syndrome: a randomized, double-blind, placebo-controlled study. (2011) (151)
- Autophagy Controls BCG-Induced Trained Immunity and the Response to Intravesical BCG Therapy for Bladder Cancer (2014) (149)
- Mycobacterium paratuberculosis is recognized by Toll‐like receptors and NOD2 (2007) (149)
- COVID-19-Associated Candidiasis (CAC): An Underestimated Complication in the Absence of Immunological Predispositions? (2020) (148)
- New Insights in the Immunobiology of IL-1 Family Members (2013) (148)
- A guide to immunotherapy for COVID-19 (2022) (146)
- Endogenous Interleukin (IL)–1α and IL-1β Are Crucial for Host Defense against Disseminated Candidiasis (2006) (146)
- The Toll-like receptor 4 Asp299Gly functional variant is associated with decreased rheumatoid arthritis disease susceptibility but does not influence disease severity and/or outcome. (2004) (144)
- Decreased plasma leptin concentrations in tuberculosis patients are associated with wasting and inflammation. (2002) (144)
- Toll-like receptors and chronic inflammation in rheumatic diseases: new developments (2016) (143)
- Beneficial response to anakinra and thalidomide in Schnitzler’s syndrome (2005) (142)
- Trained Immunity-Based Vaccines: A New Paradigm for the Development of Broad-Spectrum Anti-infectious Formulations (2018) (142)
- Current gaps in sepsis immunology: new opportunities for translational research. (2019) (142)
- Pro‐inflammatory cytokines in patients with essential hypertension (2001) (141)
- Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity (2016) (140)
- Inter-individual variability and genetic influences on cytokine responses to bacteria and fungi (2016) (139)
- Innate immune cell activation and epigenetic remodeling in symptomatic and asymptomatic atherosclerosis in humans in vivo. (2016) (138)
- Immunometabolic circuits in trained immunity. (2016) (138)
- Interleukin‐18 induces production of proinflammatory cytokines in mice: no intermediate role for the cytokines of the tumor necrosis factor family and interleukin‐1β (2000) (137)
- Innate immune mechanisms for recognition and uptake of Candida species. (2010) (137)
- The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis (2011) (136)
- Effect of Vegan Fecal Microbiota Transplantation on Carnitine‐ and Choline‐Derived Trimethylamine‐N‐Oxide Production and Vascular Inflammation in Patients With Metabolic Syndrome (2018) (136)
- Non‐LPS components of Chlamydia pneumoniae stimulate cytokine production through Toll‐like receptor 2‐dependent pathways (2002) (134)
- Monocyte and macrophage immunometabolism in atherosclerosis (2017) (134)
- Differential Effects of Environmental and Genetic Factors on T and B Cell Immune Traits (2016) (133)
- Trained immunity: A smart way to enhance innate immune defence. (2015) (132)
- Aspergillus fumigatus conidial melanin modulates host cytokine response. (2010) (132)
- Role of gut microbiota in chronic low‐grade inflammation as potential driver for atherosclerotic cardiovascular disease: a systematic review of human studies (2018) (131)
- Inhibiting Inflammation with Myeloid Cell‐Specific Nanobiologics Promotes Organ Transplant Acceptance (2018) (131)
- Toll-like receptor 1 polymorphisms increase susceptibility to candidemia. (2012) (131)
- Innate immune memory: An evolutionary perspective (2018) (131)
- TLR2 & Co: a critical analysis of the complex interactions between TLR2 and coreceptors (2013) (128)
- Salmonella septicemia in rheumatoid arthritis patients receiving anti-tumor necrosis factor therapy: association with decreased interferon-gamma production and Toll-like receptor 4 expression. (2003) (127)
- Th17 responses and host defense against microorganisms: an overview. (2009) (127)
- Specific and Complex Reprogramming of Cellular Metabolism in Myeloid Cells during Innate Immune Responses. (2017) (127)
- Outcomes of controlled human malaria infection after BCG vaccination (2019) (127)
- Growth of Candida albicans Cells on the Physiologically Relevant Carbon Source Lactate Affects Their Recognition and Phagocytosis by Immune Cells (2012) (126)
- An IFN-γ-Independent Proinflammatory Role of IL-18 in Murine Streptococcal Cell Wall Arthritis (2000) (126)
- Plasmodium falciparum Infection Causes Proinflammatory Priming of Human TLR Responses1 (2007) (126)
- The role of interferon-gamma in the increased tuberculosis risk in type 2 diabetes mellitus (2008) (126)
- Triggering receptor expressed on myeloid cells‐1 (TREM‐1) amplifies the signals induced by the NACHT‐LRR (NLR) pattern recognition receptors (2006) (125)
- Unique metabolic activation of adipose tissue macrophages in obesity promotes inflammatory responses (2018) (125)
- Candida and Host Determinants of Susceptibility to Invasive Candidiasis (2013) (122)
- Endoplasmic Reticulum α-Glycosidases of Candida albicans Are Required for N Glycosylation, Cell Wall Integrity, and Normal Host-Fungus Interaction (2007) (121)
- Crystals of monosodium urate monohydrate enhance lipopolysaccharide-induced release of interleukin 1β by mononuclear cells through a caspase 1-mediated process (2008) (121)
- Corticosteroids Block Autophagy Protein Recruitment in Aspergillus fumigatus Phagosomes via Targeting Dectin-1/Syk Kinase Signaling (2013) (120)
- Anti‐Aspergillus human host defence relies on type 1 T helper (Th1), rather than type 17 T helper (Th17), cellular immunity (2010) (119)
- Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients (2020) (119)
- The Inhibitory Innate Immune Sensor NLRP12 Maintains a Threshold against Obesity by Regulating Gut Microbiota Homeostasis. (2018) (117)
- The Y238X stop codon polymorphism in the human β-glucan receptor dectin-1 and susceptibility to invasive aspergillosis. (2011) (117)
- Vildagliptin Improves Endothelium-Dependent Vasodilatation in Type 2 Diabetes (2011) (116)
- Genomic analysis of Andamanese provides insights into ancient human migration into Asia and adaptation (2016) (116)
- Low-tidal-volume Mechanical Ventilation Induces a Toll-like Receptor 4–dependent Inflammatory Response in Healthy Mice (2008) (116)
- Anti-inflammatory therapy with tumour necrosis factor alpha inhibitors improves high-density lipoprotein cholesterol antioxidative capacity in rheumatoid arthritis patients (2008) (115)
- BCG-induced protection: effects on innate immune memory. (2014) (114)
- The Potential Role of Trained Immunity in Autoimmune and Autoinflammatory Disorders (2018) (114)
- Targeting of Toll-like receptors: a decade of progress in combating infectious diseases. (2011) (113)
- Novel Structural Features in Candida albicans Hyphal Glucan Provide a Basis for Differential Innate Immune Recognition of Hyphae Versus Yeast* (2013) (113)
- Gut Microbial Associations to Plasma Metabolites Linked to Cardiovascular Phenotypes and Risk. (2019) (113)
- Immunological memory: lessons from the past and a look to the future (2016) (113)
- Trained Innate Immunity, Epigenetics, and Covid-19. (2020) (113)
- Recognition of DHN-melanin by a C-type lectin receptor is required for immunity to Aspergillus (2018) (112)
- Modulation of Toll-Like Receptor 2 (TLR2) and TLR4 Responses by Aspergillus fumigatus (2009) (112)
- Mycobacterial growth inhibition is associated with trained innate immunity (2018) (110)
- Rewiring cellular metabolism via the AKT/mTOR pathway contributes to host defence against Mycobacterium tuberculosis in human and murine cells (2016) (109)
- Acellular components of Chlamydia pneumoniae stimulate cytokine production in human blood mononuclear cells (2000) (108)
- Reconstructing the Population History of European Romani from Genome-wide Data (2012) (108)
- A Polysaccharide Virulence Factor from Aspergillus fumigatus Elicits Anti-inflammatory Effects through Induction of Interleukin-1 Receptor Antagonist (2014) (108)
- The Tetraspanin Protein CD37 Regulates IgA Responses and Anti-Fungal Immunity (2009) (108)
- STAT1 Hyperphosphorylation and Defective IL12R/IL23R Signaling Underlie Defective Immunity in Autosomal Dominant Chronic Mucocutaneous Candidiasis (2011) (108)
- An open label trial of anakinra to prevent respiratory failure in COVID-19 (2020) (107)
- Mechanical Ventilation in Healthy Mice Induces Reversible Pulmonary and Systemic Cytokine Elevation with Preserved Alveolar Integrity: An In Vivo Model Using Clinical Relevant Ventilation Settings (2007) (107)
- Recognition of fungal pathogens by toll-like receptors. (2006) (107)
- Interleukin-1β in innate inflammation, autophagy and immunity. (2013) (107)
- Physiological and Genetic Adaptations to Diving in Sea Nomads (2018) (107)
- Role of TLR1 and TLR6 in the host defense against disseminated candidiasis. (2008) (106)
- Vitamin D(3) down-regulates proinflammatory cytokine response to Mycobacterium tuberculosis through pattern recognition receptors while inducing protective cathelicidin production. (2011) (106)
- Genetic susceptibility to Candida infections (2013) (106)
- Inflammation-dependent secretion and splicing of IL-32γ in rheumatoid arthritis (2011) (105)
- Tumour necrosis factor alpha-driven IL-32 expression in rheumatoid arthritis synovial tissue amplifies an inflammatory cascade (2010) (105)
- Mucosal barrier injury, fever and infection in neutropenic patients with cancer: introducing the paradigm febrile mucositis (2014) (105)
- A Multifunctional Mannosyltransferase Family in Candida albicans Determines Cell Wall Mannan Structure and Host-Fungus Interactions* (2010) (104)
- Towards precision medicine in sepsis: a position paper from the European Society of Clinical Microbiology and Infectious Diseases. (2018) (102)
- Mortality in children with complicated severe acute malnutrition is related to intestinal and systemic inflammation: an observational cohort study12 (2016) (100)
- Two patients with cryptococcal meningitis and idiopathic CD4 lymphopenia: defective cytokine production and reversal by recombinant interferon- gamma therapy. (2004) (100)
- Autophagy in adipose tissue and the beta cell: implications for obesity and diabetes (2014) (99)
- Gain‐of‐function STAT1 mutations impair STAT3 activity in patients with chronic mucocutaneous candidiasis (CMC) (2015) (99)
- The inflammasome and caspase-1 activation: a new mechanism underlying increased inflammatory activity in human visceral adipose tissue. (2011) (99)
- Functional and genetic evidence that the Mal/TIRAP allele variant 180L has been selected by providing protection against septic shock (2009) (98)
- Immunodeficiency and genetic defects of pattern-recognition receptors. (2011) (97)
- Inflammasome-independent Role of Apoptosis-associated Speck-like Protein Containing a CARD (ASC) in T Cell Priming Is Critical for Collagen-induced Arthritis* (2010) (96)
- Mycobacterium tuberculosis induces IL‐17A responses through TLR4 and dectin‐1 and is critically dependent on endogenous IL‐1 (2010) (95)
- SUCNR1-mediated chemotaxis of macrophages aggravates obesity-induced inflammation and diabetes (2017) (95)
- BCG Vaccination Induces Long-Term Functional Reprogramming of Human Neutrophils (2020) (95)
- Candida albicans Dampens Host Defense by Downregulating IL-17 Production (2010) (94)
- The effect of renin–angiotensin system inhibitors on pro‐ and anti‐inflammatory cytokine production (1998) (94)
- Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation. (2015) (94)
- Bartonella quintana Lipopolysaccharide Is a Natural Antagonist of Toll-Like Receptor 4 (2007) (93)
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- Long‐term reprogramming of the innate immune system (2018) (93)
- Uric acid priming in human monocytes is driven by the AKT–PRAS40 autophagy pathway (2017) (93)
- β-Glucan Induces Protective Trained Immunity against Mycobacterium tuberculosis Infection: A Key Role for IL-1 (2020) (93)
- Treatment with Statins Does Not Revert Trained Immunity in Patients with Familial Hypercholesterolemia. (2019) (93)
- Trained Innate Immunity as a Novel Mechanism Linking Infection and the Development of Atherosclerosis (2018) (93)
- The IL‐36 receptor pathway regulates Aspergillus fumigatus‐induced Th1 and Th17 responses (2013) (93)
- Impaired dendritic cell function in Crohn’s disease patients with NOD2 3020insC mutation (2006) (92)
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- Black Yeasts and Their Filamentous Relatives: Principles of Pathogenesis and Host Defense (2014) (78)
- The Frameshift Mutation in Nod2 Results in Unresponsiveness Not Only to Nod2- but Also Nod1-activating Peptidoglycan Agonists* (2005) (78)
- Circulating Leptin and Adiponectin Concentrations During Tumor Necrosis Factor Blockade in Patients with Active Rheumatoid Arthritis (2009) (78)
- Hypoxia Promotes Immune Evasion by Triggering β-Glucan Masking on the Candida albicans Cell Surface via Mitochondrial and cAMP-Protein Kinase A Signaling (2018) (78)
- Engagement of NOD2 has a dual effect on proIL‐1β mRNA transcription and secretion of bioactive IL‐1β (2008) (78)
- Skin Microbiome Imbalance in Patients with STAT1/STAT3 Defects Impairs Innate Host Defense Responses (2013) (78)
- CLEC4F Is an Inducible C-Type Lectin in F4/80-Positive Cells and Is Involved in Alpha-Galactosylceramide Presentation in Liver (2013) (78)
- Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses (2018) (78)
- Bypassing pathogen-induced inflammasome activation for the regulation of interleukin-1beta production by the fungal pathogen Candida albicans. (2009) (77)
- Contributions of Neisseria meningitidis LPS and non‐LPS to proinflammatory cytokine response (2001) (77)
- Pharmacologic inhibitors of tumor necrosis factor production exert differential effects in lethal endotoxemia and in infection with live microorganisms in mice. (1995) (76)
- Fungal Chitin Induces Trained Immunity in Human Monocytes during Cross-talk of the Host with Saccharomyces cerevisiae* (2016) (76)
- Anti-mycobacterial activity correlates with altered DNA methylation pattern in immune cells from BCG-vaccinated subjects (2017) (76)
- Mendelian genetics of human susceptibility to fungal infection. (2014) (76)
- Convergent evolution in European and Rroma populations reveals pressure exerted by plague on Toll-like receptors (2014) (76)
- The Candida Th17 response is dependent on mannan- and beta-glucan-induced prostaglandin E2. (2010) (76)
- T-cell Subsets and Antifungal Host Defenses (2010) (75)
- A TIR Domain Variant of MyD88 Adapter-like (Mal)/TIRAP Results in Loss of MyD88 Binding and Reduced TLR2/TLR4 Signaling* (2009) (75)
- Innate immune memory: Implications for host responses to damage‐associated molecular patterns (2016) (75)
- Toll-like receptor triggering in cord blood mesenchymal stem cells (2009) (74)
- Cutting Edge: Plasmodium falciparum Induces Trained Innate Immunity (2018) (74)
- Effects of oral butyrate supplementation on inflammatory potential of circulating peripheral blood mononuclear cells in healthy and obese males (2019) (73)
- Gene polymorphisms in pattern recognition receptors and susceptibility to idiopathic recurrent vulvovaginal candidiasis (2014) (73)
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- The toll-like receptor 4 Asp299Gly variant and tuberculosis susceptibility in HIV-infected patients in Tanzania (2007) (73)
- Increased Plasma Heparanase Activity in COVID-19 Patients (2020) (72)
- Blocking IL-1 to prevent respiratory failure in COVID-19 (2020) (72)
- Cellular metabolism of myeloid cells in sepsis (2017) (72)
- Increased susceptibility to systemic candidiasis in interleukin-6 deficient mice. (1999) (72)
- Enhanced interleukin-1β production of PBMCs from patients with gout after stimulation with Toll-like receptor-2 ligands and urate crystals (2012) (72)
- Effects of Hydrophobicity on the Antifungal Activity of α‐Helical Antimicrobial Peptides (2008) (71)
- Phagocytosis and intracellular killing of Candida albicans blastoconidia by neutrophils and macrophages: a comparison of different microbiological test systems. (2002) (71)
- Recognition of Borrelia burgdorferi by NOD2 is central for the induction of an inflammatory reaction. (2010) (71)
- Role of the dual interaction of fungal pathogens with pattern recognition receptors in the activation and modulation of host defence. (2006) (71)
- Iso-osmolar prehydration shifts the cytokine response towards a more anti-inflammatory balance in human endotoxemia (2005) (71)
- Functional consequences of the Asp299Gly Toll-like receptor-4 polymorphism. (2005) (71)
- Early Serum Galactomannan Trend as a Predictor of Outcome of Invasive Aspergillosis (2012) (71)
- 1,25‐Dihydroxyvitamin D3 inhibits proliferation but not the suppressive function of regulatory T cells in the absence of antigen‐presenting cells (2011) (70)
- Pathogenic NLRP3 Inflammasome Activity during Candida Infection Is Negatively Regulated by IL-22 via Activation of NLRC4 and IL-1Ra. (2015) (70)
- Interleukin 32 (IL-32) Contains a Typical α-Helix Bundle Structure That Resembles Focal Adhesion Targeting Region of Focal Adhesion Kinase-1* (2011) (70)
- The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives (2020) (70)
- Variable recognition of Candida albicans strains by TLR4 and lectin recognition receptors. (2010) (70)
- Complement Activation in the Disease Course of Coronavirus Disease 2019 and Its Effects on Clinical Outcomes (2020) (69)
- Interplay between redox status and inflammasome activation. (2011) (68)
- Autophagy modulates the Mycobacterium tuberculosis‐induced cytokine response (2011) (68)
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- The interplay between central metabolism and innate immune responses. (2014) (68)
- Antifungal innate immunity: recognition and inflammatory networks (2015) (68)
- Diabetes Mellitus and Increased Tuberculosis Susceptibility: The Role of Short-Chain Fatty Acids (2015) (68)
- Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome (2018) (68)
- NOD2 3020insC mutation and the pathogenesis of Crohn's disease: impaired IL-1beta production points to a loss-of-function phenotype. (2005) (68)
- Neonatal BCG Vaccination Influences Cytokine Responses to Toll-like Receptor Ligands and Heterologous Antigens (2018) (67)
- Rewiring monocyte glucose metabolism via C-type lectin signaling protects against disseminated candidiasis (2017) (67)
- Neutrophil-Mediated Inhibition of Proinflammatory Cytokine Responses (2012) (67)
- Safety and COVID-19 Symptoms in Individuals Recently Vaccinated with BCG: a Retrospective Cohort Study (2020) (66)
- Trained Immunity-Promoting Nanobiologic Therapy Suppresses Tumor Growth and Potentiates Checkpoint Inhibition (2020) (66)
- BCG vaccination in humans inhibits systemic inflammation in a sex-dependent manner. (2020) (66)
- Seasonal Variation in Vitamin D3 Levels Is Paralleled by Changes in the Peripheral Blood Human T Cell Compartment (2012) (66)
- Differential function of the NACHT-LRR (NLR) members Nod1 and Nod2 in arthritis (2008) (65)
- Trained immunity as a molecular mechanism for BCG immunotherapy in bladder cancer (2020) (65)
- A comprehensive analysis of pattern recognition receptors in normal and inflamed human epidermis: upregulation of dectin-1 in psoriasis. (2010) (65)
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- Dectin-1 plays a redundant role in the immunomodulatory activities of β-glucan-rich ligands in vivo (2013) (64)
- Complement plays a central role in Candida albicans‐induced cytokine production by human PBMCs (2012) (64)
- Metformin Alters Human Host Responses to Mycobacterium tuberculosis in Healthy Subjects (2019) (64)
- Crohn’s disease patients homozygous for the 3020insC NOD2 mutation have a defective NOD2/TLR4 cross‐tolerance to intestinal stimuli (2008) (64)
- ICU-acquired immunosuppression and the risk for secondary fungal infections. (2011) (64)
- Interleukin-18 resistance in patients with obesity and type 2 diabetes mellitus (2008) (63)
- Gut microbial co-abundance networks show specificity in inflammatory bowel disease and obesity (2020) (63)
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- Activation of innate host defense mechanisms by Borrelia. (2010) (63)
- Recombinant murine granulocyte colony-stimulating factor protects against acute disseminated Candida albicans infection in nonneutropenic mice. (1998) (63)
- Human dendritic cells are less potent at killing Candida albicans than both monocytes and macrophages. (2004) (63)
- Understanding human immune function using the resources from the Human Functional Genomics Project (2016) (63)
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- Whole Blood Profiling of Bacillus Calmette–Guérin-Induced Trained Innate Immunity in Infants Identifies Epidermal Growth Factor, IL-6, Platelet-Derived Growth Factor-AB/BB, and Natural Killer Cell Activation (2017) (62)
- Cutaneous Granulomas in Ataxia Telangiectasia and Other Primary Immunodeficiencies: Reflection of Inappropriate Immune Regulation? (2011) (62)
- Polymorphisms in Autophagy Genes and Susceptibility to Tuberculosis (2012) (62)
- CXCR1-mediated neutrophil degranulation and fungal killing promote Candida clearance and host survival (2016) (62)
- Inhibition of caspase-1 activation in gram-negative sepsis and experimental endotoxemia (2011) (62)
- Modulation of neutrophil function in host defense against disseminated Candida albicans infection in mice. (1999) (61)
- The Inflammatory Response Induced by Aspartic Proteases of Candida albicans Is Independent of Proteolytic Activity (2010) (61)
- TLR1/TLR2 Heterodimers Play an Important Role in the Recognition of Borrelia Spirochetes (2011) (61)
- Alpha-1-anti-trypsin-Fc fusion protein ameliorates gouty arthritis by reducing release and extracellular processing of IL-1β and by the induction of endogenous IL-1Ra (2015) (60)
- The discriminative capacity of soluble Toll-like receptor (sTLR)2 and sTLR4 in inflammatory diseases (2014) (60)
- Recurrent Vulvovaginal Candidiasis: An Immunological Perspective (2020) (60)
- Differential IL-17 Production and Mannan Recognition Contribute to Fungal Pathogenicity and Commensalism (2010) (60)
- The Role of Endogenous Interleukin (IL)-18, IL-12, IL-1β, and Tumor Necrosis Factor-α in the Production of Interferon-γ Induced by Candida albicans in Human Whole-Blood Cultures (2002) (60)
- Differential Toll-Like Receptor Recognition and Induction of Cytokine Profile by Bifidobacterium breve and Lactobacillus Strains of Probiotics (2011) (60)
- Pattern recognition pathways leading to a Th2 cytokine bias in allergic bronchopulmonary aspergillosis patients (2015) (60)
- Interleukin-32: a predominantly intracellular proinflammatory mediator that controls cell activation and cell death. (2012) (60)
- Proinflammatory Effects of Hypoglycemia in Humans With or Without Diabetes (2017) (59)
- Selective regulation of intercellular adhesion molecule‐1 expression by interleukin‐18 and interleukin‐12 on human monocytes (2003) (59)
- TREM-1 interaction with the LPS/TLR4 receptor complex. (2011) (59)
- Candida albicans Primes TLR Cytokine Responses through a Dectin-1/Raf-1–Mediated Pathway (2013) (59)
- Differential role of IL‐18 and IL‐12 in the host defense against disseminated Candida albicans infection (2003) (59)
- The classical CD14++CD16− monocytes, but not the patrolling CD14+CD16+ monocytes, promote Th17 responses to Candida albicans (2011) (59)
- Long‐term in vitro and in vivo effects of γ‐irradiated BCG on innate and adaptive immunity (2015) (58)
- Aldosterone induces trained immunity: the role of fatty acid synthesis. (2019) (58)
- Aspergillus Cell Wall Chitin Induces Anti- and Proinflammatory Cytokines in Human PBMCs via the Fc-γ Receptor/Syk/PI3K Pathway (2016) (58)
- Toll‐like receptor‐4 Asp299Gly polymorphism does not influence progression of atherosclerosis in patients with familial hypercholesterolaemia (2004) (57)
- Induction of trained immunity by influenza vaccination - impact on COVID-19 (2021) (57)
- Remembering Pathogen Dose: Long-Term Adaptation in Innate Immunity. (2018) (57)
- Trained Immunity Confers Broad-Spectrum Protection Against Bacterial Infections (2019) (57)
- The RIG-I-like helicase receptor MDA5 (IFIH1) is involved in the host defense against Candida infections (2015) (56)
- Cytokine responses and regulation of interferon-gamma release by human mononuclear cells to Aspergillus fumigatus and other filamentous fungi. (2005) (56)
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- The epigenetic memory of monocytes and macrophages as a novel drug target in atherosclerosis. (2015) (55)
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- Chlamydia pneumoniae stimulates IFN-gamma synthesis through MyD88-dependent, TLR2- and TLR4-independent induction of IL-18 release. (2004) (55)
- Cell Wall Changes in Amphotericin B-Resistant Strains from Candida tropicalis and Relationship with the Immune Responses Elicited by the Host (2016) (55)
- Vav Proteins Are Key Regulators of Card9 Signaling for Innate Antifungal Immunity (2016) (55)
- Redundant role of TLR9 for anti-Candida host defense. (2008) (54)
- LPS-induced cytokine production and expression of LPS-receptors by peripheral blood mononuclear cells of patients with familial hypercholesterolemia and the effect of HMG-CoA reductase inhibitors. (1998) (54)
- Early proinflammatory cytokines and C‐reactive protein trends as predictors of outcome in invasive Aspergillosis. (2010) (54)
- Low Induction of Proinflammatory Cytokines Parallels Evolutionary Success of Modern Strains within the Mycobacterium tuberculosis Beijing Genotype (2013) (54)
- PPAR-alpha dependent regulation of vanin-1 mediates hepatic lipid metabolism. (2014) (54)
- Severe Candida spp. infections: new insights into natural immunity. (2010) (54)
- Role of Interleukin-18 in Host Defense against Disseminated Candida albicans Infection (2002) (53)
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- Non-canonical signalling mediates changes in fungal cell wall PAMPs that drive immune evasion (2019) (53)
- Vitamin A induces inhibitory histone methylation modifications and down‐regulates trained immunity in human monocytes (2015) (53)
- Mast Cells Induce Vascular Smooth Muscle Cell Apoptosis via a Toll-Like Receptor 4 Activation Pathway (2012) (53)
- Host defence against disseminated Candida albicans infection and implications for antifungal immunotherapy (2006) (53)
- Hyperferritinaemia in Dengue Virus Infected Patients Is Associated with Immune Activation and Coagulation Disturbances (2014) (53)
- Antibody neutralization of microbiota-derived circulating peptidoglycan dampens inflammation and ameliorates autoimmunity (2019) (53)
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- Innate immune memory: implications for development of pediatric immunomodulatory agents and adjuvanted vaccines (2013) (50)
- New live attenuated tuberculosis vaccine MTBVAC induces trained immunity and confers protection against experimental lethal pneumonia (2020) (49)
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- Outcomes Associated With Use of a Kinin B2 Receptor Antagonist Among Patients With COVID-19 (2020) (48)
- Catecholamines Induce Trained Immunity in Monocytes In Vitro and In Vivo (2020) (48)
- Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial (2021) (48)
- Differential effects of platelets and platelet inhibition by ticagrelor on TLR2- and TLR4-mediated inflammatory responses (2015) (47)
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- Immunometabolic control of trained immunity (2020) (47)
- Early clearance of Mycobacterium tuberculosis is associated with increased innate immune responses. (2019) (47)
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- Genetic Basis for Recurrent Vulvo-Vaginal Candidiasis (2013) (46)
- Trained Immunity and Local Innate Immune Memory in the Lung (2018) (46)
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- Intensive insulin therapy does not alter the inflammatory response in patients undergoing coronary artery bypass grafting: a randomized controlled trial [ISRCTN95608630] (2005) (46)
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- Diabetes propels the risk for cardiovascular disease: sweet monocytes becoming aggressive? (2016) (46)
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- Transcriptional and functional insights into the host immune response against the emerging fungal pathogen Candida auris (2020) (45)
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- Differential role of NK cells against Candida albicans infection in immunocompetent or immunocompromised mice (2014) (45)
- Receptor Recognition of and Immune Intracellular Pathways for Veillonella parvula Lipopolysaccharide (2009) (45)
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- Genetic Association Analysis of the Functional c.714T>G Polymorphism and Mucosal Expression of Dectin-1 in Inflammatory Bowel Disease (2009) (44)
- Borrelia species induce inflammasome activation and IL‐17 production through a caspase‐1‐dependent mechanism (2011) (44)
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- Sex-Specific Regulation of Inflammation and Metabolic Syndrome in Obesity (2020) (44)
- Biomarkers for antimicrobial stewardship: a reappraisal in COVID-19 times? (2020) (44)
- Risks of Ruxolitinib in STAT1 Gain-of-Function-Associated Severe Fungal Disease (2017) (43)
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- Rewiring of glucose metabolism defines trained immunity induced by oxidized low-density lipoprotein (2020) (43)
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- Cryptococcus gattii Induces a Cytokine Pattern That Is Distinct from Other Cryptococcal Species (2013) (43)
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- Different Patterns of Toll-Like Receptor 2 Polymorphisms in Populations of Various Ethnic and Geographic Origins (2012) (41)
- Origins, admixture and founder lineages in European Roma (2015) (41)
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- Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease (2021) (17)
- Neisseria meningitidis lipid A mutant LPSs function as LPS antagonists in humans by inhibiting TLR 4-dependent cytokine production (2011) (17)
- Posttranscriptional Down-Regulation of Tumor Necrosis Factor-a and Interleukin-1β Production in Acute Meningococcal Infections (1998) (17)
- Native LDL potentiate TNF alpha and IL-8 production by human mononuclear cells. (2002) (17)
- Phagocytosis and intracellular killing of Candida albicans by murine polymorphonuclear neutrophils. (2012) (17)
- Single-cell transcriptomic profiles reveal changes associated with BCG-induced trained immunity and protective effects in circulating monocytes. (2021) (17)
- Hypothesis: Normalisation of cytokine dysbalance explains the favourable effects of strict glucose regulation in the critically ill. (2004) (17)
- The NLRP1-IL18 Connection: A Stab in the Back of Obesity-Induced Inflammation. (2016) (17)
- Primary immunodeficiencies of pattern recognition receptors (2012) (17)
- BCG vaccination provides protection against IAV but not SARS-CoV-2 (2022) (17)
- IL-1 family cytokines as drivers and inhibitors of trained immunity. (2021) (17)
- Interleukin-18 does not modulate the acute-phase response (2005) (16)
- Trained Immunity: Long-Term Adaptation in Innate Immune Responses. (2020) (16)
- Acromegaly, inflammation and cardiovascular disease: a review (2020) (16)
- Neonatal BCG vaccination is associated with a long-term DNA methylation signature in circulating monocytes (2022) (16)
- Proinflammatory Cytokines in the Treatment of Bacterial and Fungal Infections (2012) (16)
- Heroin Use Is Associated with Suppressed Pro-Inflammatory Cytokine Response after LPS Exposure in HIV-Infected Individuals (2015) (16)
- Efficacy of Bacillus Calmette-Guérin vaccination against respiratory tract infections in the elderly during the Covid-19 pandemic. (2022) (16)
- The Janus face of Bartonella quintana recognition by Toll-like receptors (TLRs): a review. (2008) (16)
- Altered interferon-γ response in patients with Q-fever fatigue syndrome. (2016) (16)
- High variability of TLR4 gene in different ethnic groups in Iran (2012) (16)
- Is non‐response to fluconazole maintenance therapy for recurrent Candida vaginitis related to sensitization to atopic reactions? (2018) (16)
- Integrating GWAS with bulk and single-cell RNA-sequencing reveals a role for LY86 in the anti-Candida host response (2020) (16)
- Coexistence of systemic lupus erythematosus, tuberous sclerosis and aggressive natural killer-cell leukaemia: coincidence or correlated? (2016) (16)
- A short course of oral aspirin increases IL-18-induced interferon-gamma production in whole blood cultures. (2000) (16)
- Environmental Signals Influencing Myeloid Cell Metabolism and Function in Diabetes (2018) (16)
- Differential effects of IL-17 pathway in disseminated candidiasis and zymosan-induced multiple organ failure. (2010) (16)
- Chocolate consumption modulates cytokine production in healthy individuals. (2013) (16)
- Gut microbiome-mediated metabolism effects on immunity in rural and urban African populations (2021) (16)
- Role of autophagy genetic variants for the risk of Candida infections. (2014) (16)
- The BNT162b2 mRNA vaccine against SARS-CoV-2 reprograms both adaptive and innate immune responses (2021) (15)
- Individualized significance of the −251 A/T single nucleotide polymorphism of interleukin-8 in severe infections (2016) (15)
- Intact interferon-γ response against Coxiella burnetii by peripheral blood mononuclear cells in chronic Q fever. (2017) (15)
- Toll‐like receptor‐4 Asp299Gly polymorphism does not influence progression of atherosclerosis in patients with familial hypercholesterolemia (2004) (15)
- Exposure to Candida albicans Polarizes a T-Cell Driven Arthritis Model towards Th17 Responses, Resulting in a More Destructive Arthritis (2012) (15)
- Immunological Memory in Innate Immunity (2013) (15)
- Digitalis-like Compounds Facilitate Non-Medullary Thyroid Cancer Redifferentiation through Intracellular Ca2+, FOS, and Autophagy-Dependent Pathways (2016) (15)
- Clinical implications of host genetic variation and susceptibility to severe or critical COVID-19 (2022) (15)
- Bacillus Calmette-Guérin vaccine to reduce healthcare worker absenteeism in COVID-19 pandemic, a randomized controlled trial (2022) (15)
- Development and validation of SCOPE score: A clinical score to predict COVID-19 pneumonia progression to severe respiratory failure (2022) (15)
- Specific in vitro interferon-gamma and IL-2 production as biomarkers during treatment of chronic Q fever (2015) (15)
- Tuberculosis endotypes to guide stratified host-directed therapy. (2021) (15)
- IL‐38 prevents induction of trained immunity by inhibition of mTOR signaling (2021) (15)
- Antigen-Independent Restriction of Pneumococcal Density by Mucosal Adjuvant Cholera Toxin Subunit B. (2016) (15)
- Bacillus Calmette-Guérin vaccination at birth and in vitro cytokine responses to non-specific stimulation. A randomized clinical trial (2017) (15)
- Single-cell RNA sequencing reveals induction of distinct trained-immunity programs in human monocytes (2022) (15)
- oxLDL-Induced Trained Immunity Is Dependent on Mitochondrial Metabolic Reprogramming (2021) (15)
- A NOD for autophagy (2010) (15)
- Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial. (2022) (15)
- Critical aneurysmal dilatation of the thoracic aorta in young adolescents with variant hyperimmunoglobulin E syndrome (2006) (15)
- Deficient Candida-specific T-helper 17 response during sepsis. (2012) (15)
- Uncoupling of IL-6 signaling and LC3-associated phagocytosis drives immunoparalysis during sepsis. (2021) (15)
- Deficient interleukin-17 production in response to Mycobacterium abscessus in cystic fibrosis (2016) (14)
- MST1R mutation as a genetic cause of Lady Windermere syndrome (2017) (14)
- Defective interferon-gamma production in patients with hairy cell leukaemia. (2008) (14)
- Adaptive Characteristics of Innate Immune Responses in Macrophages. (2016) (14)
- Defective cytokine production early after multiple traumas: Modulation in severe sepsis. (2015) (14)
- Neuraminidase and SIGLEC15 modulate the host defense against pulmonary aspergillosis (2021) (14)
- INTERACTING NON-SPECIFIC IMMUNOLOGICAL EFFECTS OF BCG AND Tdapf VACCINATIONS: AN EXPLORATIVE RANDOMIZED TRIAL. (2019) (14)
- Hypoglycaemia downregulates endotoxin-induced production of tumour necrosis factor-alpha, but does not affect IL-1beta, IL-6, or IL-10. (2003) (14)
- The Candida Th 17 response is dependent on mannan-and b-glucan-induced prostaglandin E 2 (2010) (14)
- Reprogramming of bone marrow myeloid progenitor cells in patients with severe coronary artery disease (2020) (14)
- Predominant Tubular Interleukin-18 Expression in Polyomavirus-Associated Nephropathy (2016) (14)
- The association of TSH and thyroid hormones with lymphopenia in bacterial sepsis and COVID-19 (2021) (14)
- Role of NOD1 polymorphism in susceptibility and clinical progression of rheumatoid arthritis. (2013) (14)
- Recurrent candidiasis and early-onset gastric cancer in a patient with a genetically defined partial MYD88 defect (2015) (14)
- Impact of Intermediate Hyperglycemia and Diabetes on Immune Dysfunction in Tuberculosis (2020) (14)
- The dipeptidyl peptidase-4 inhibitor vildagliptin does not affect ex vivo cytokine response and lymphocyte function in patients with type 2 diabetes mellitus. (2014) (14)
- Lysine methyltransferase G9a is an important modulator of trained immunity (2021) (13)
- Involvement of Lactate and Pyruvate in the Anti-Inflammatory Effects Exerted by Voluntary Activation of the Sympathetic Nervous System (2020) (13)
- Author Correction: Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial (2021) (13)
- NFKB2 polymorphisms associate with the risk of developing rheumatoid arthritis and response to TNF inhibitors: Results from the REPAIR consortium (2020) (13)
- H4:IC31 Vaccine or BCG Revaccination for Tuberculosis. (2018) (13)
- The Loss of Functional Caspase-12 in Europe Is a Pre-Neolithic Event (2012) (13)
- Borrelia-induced cytokine production is mediated by spleen tyrosine kinase (Syk) but is Dectin-1 and Dectin-2 independent. (2015) (13)
- Borrelia burgdorferi hijacks cellular metabolism of immune cells: Consequences for host defense. (2020) (13)
- Effects of fecal microbiota transplant on DNA methylation in subjects with metabolic syndrome (2021) (13)
- Systemic administration of β-glucan induces immune training in microglia (2020) (13)
- The effects of dexamethasone and chlorpromazine on tumour necrosis factor-alpha, interleukin-1 beta, interleukin-1 receptor antagonist and interleukin-10 in human volunteers. (1997) (13)
- Persistent inflammation and endothelial dysfunction in patients with treated acromegaly (2019) (13)
- Y-Chromosome Analysis in Individuals Bearing the Basarab Name of the First Dynasty of Wallachian Kings (2012) (13)
- Genetic variations in innate immunity genes affect response to Coxiella burnetii and are associated with susceptibility to chronic Q fever. (2019) (13)
- The specifics of innate immune memory (2020) (13)
- Lower incidence of Pneumocystis jirovecii pneumonia among Africans in the Netherlands host or environmental factors? (2013) (13)
- Comment on “Detection of an Infectious Retrovirus, XMRV, in Blood Cells of Patients with Chronic Fatigue Syndrome” (2010) (13)
- Modulation of Toll-like receptor ligands and Candida albicans-induced cytokine responses by specific probiotics. (2012) (13)
- Tissue Metabolic Changes Drive Cytokine Responses to Mycobacterium tuberculosis (2018) (13)
- The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives. (2021) (13)
- Increased NEFA levels reduce blood Mg2+ in hypertriacylglycerolaemic states via direct binding of NEFA to Mg2+ (2018) (13)
- More than inflammation: interleukin-1beta polymorphisms and the lipid metabolism. (2011) (13)
- Swarm Learning as a privacy-preserving machine learning approach for disease classification (2020) (13)
- Hypoglycaemia downregulates endotoxin-induced production of tumour necrosis factor-α, but does not affect IL-1β, IL-6, or IL-10 (2003) (13)
- Posttranscriptional down-regulation of tumor necrosis factor-alpha and interleukin-1beta production in acute meningococcal infections. (1998) (12)
- The Architecture of Circulating Immune Cells Is Dysregulated in People Living With HIV on Long Term Antiretroviral Treatment and Relates With Markers of the HIV-1 Reservoir, Cytomegalovirus, and Microbial Translocation (2021) (12)
- Glutathione Metabolism Contributes to the Induction of Trained Immunity (2021) (12)
- Multi-omics examination of Q fever fatigue syndrome identifies similarities with chronic fatigue syndrome (2020) (12)
- Immunomodulatory aged neutrophils are augmented in blood and skin of psoriasis patients. (2021) (12)
- A novel mutation in the TG gene (G2322S) causing congenital hypothyroidism in a Sudanese family: a case report (2018) (12)
- ESCAPE: An Open-Label Trial of Personalized Immunotherapy in Critically lll COVID-19 Patients (2021) (12)
- The Effects of Selective Hematopoietic Expression of Human IL-37 on Systemic Inflammation and Atherosclerosis in LDLr-Deficient Mice (2017) (12)
- Development of Endotoxin Tolerance Does Not Influence the Response to a Challenge with the Mucosal Live-Attenuated Influenza Vaccine in Humans In Vivo (2017) (12)
- Sepsis--theory and therapies. (2003) (12)
- Atherogenic effects of Chlamydia pneumoniae: refuting the innocent bystander hypothesis. (2003) (12)
- Increased voluntary exercise in mice deficient for tumour necrosis factor‐α and lymphotoxin‐α (2007) (12)
- Roles of Trained Immunity in the Pathogenesis of Cholangiopathies: A Therapeutic Target (2020) (11)
- Hepatitis C Virus Reactivation Following COVID-19 Vaccination – A Case Report (2021) (11)
- The Carpathian range represents a weak genetic barrier in South-East Europe (2014) (11)
- Discovery, diversity, and functional associations of crAss-like phages in human gut metagenomes from four Dutch cohorts (2022) (11)
- An integrative genomics approach identifies KDM4 as a modulator of trained immunity (2021) (11)
- The effect of salicylates on insulin sensitivity. (2001) (11)
- Persistence of full-length caspase-12 and its relation to malaria in West and Central African populations. (2010) (11)
- Master and commander: epigenetic regulation of macrophages (2016) (11)
- Genetic variant in IL-32 is associated with the ex vivo cytokine production of anti-TNF treated PBMCs from rheumatoid arthritis patients (2018) (11)
- 35th Annual meeting of the European Association for the Study of Diabetes. Brussels, Belgium, 28 September-2 October, 1999. Abstracts. (1999) (11)
- Treatment of Intra-Abdominal Abscesses Caused by Candida albicans with Antifungal Agents and Recombinant Murine Granulocyte Colony-Stimulating Factor (2003) (11)
- Defects of pattern recognition: primary immunodeficiencies of the innate immune system. (2011) (11)
- Antifungal immune responses: emerging host–pathogen interactions and translational implications (2018) (11)
- Characterization of the Acute Inflammatory Response in Measles Infection. (2014) (11)
- Immune memory characteristics of innate lymphoid cells (2019) (11)
- Controlled Human Malaria Infection Induces Long-Term Functional Changes in Monocytes (2020) (11)
- CRELD1 modulates homeostasis of the immune system in mice and humans (2020) (11)
- Adaptation and memory in innate immunity. (2016) (10)
- IL-1 Mediates Tissue-Specific Inflammation and Severe Respiratory Failure in COVID-19 (2022) (10)
- The Effect of Rosuvastatin on Markers of Immune Activation in Treatment-Naive Human Immunodeficiency Virus-Patients (2015) (10)
- Cytokine inhibition in chronic fatigue syndrome patients: study protocol for a randomized controlled trial (2015) (10)
- Differential effects of BCG vaccine on immune responses induced by vi polysaccharide typhoid fever vaccination: an explorative randomized trial (2020) (10)
- Genome of Peştera Muierii skull shows high diversity and low mutational load in pre-glacial Europe (2021) (10)
- Trained innate immunity as a mechanistic link between sepsis and atherosclerosis (2014) (10)
- Rare NOX3 Variants Confer Susceptibility to Agranulocytosis During Thyrostatic Treatment of Graves' Disease (2017) (10)
- Author response: The Human Cell Atlas (2017) (10)
- Deficiency of interleukin-1 receptor-associated kinase 4 presenting as fatal Pseudomonas aeruginosa bacteremia in two siblings. (2015) (10)
- Variation in Genes of β-glucan Recognition Pathway and Susceptibility to Opportunistic Infections in HIV-Positive Patients (2011) (10)
- Genetic variation in TLR10 is not associated with chronic Q fever, despite the inhibitory effect of TLR10 on Coxiella burnetii-induced cytokines in vitro. (2016) (10)
- Recent common origin, reduced population size, and marked admixture have shaped European Roma genomes. (2020) (10)
- A modular approach toward producing nanotherapeutics targeting the innate immune system (2021) (10)
- Functional Annotation of Genetic Loci Associated With Sepsis Prioritizes Immune and Endothelial Cell Pathways (2019) (10)
- Effects of Bacillus Calmette-Guérin (BCG) vaccination at birth on T and B lymphocyte subsets: Results from a clinical randomized trial (2017) (10)
- Cytokine profiles in patients with Q fever fatigue syndrome. (2019) (10)
- Trained immunity: adaptation within innate immune mechanisms. (2022) (9)
- Leukocyte-Released Mediators in Response to Both Bacterial and Fungal Infections Trigger IFN Pathways, Independent of IL-1 and TNF-α, in Endothelial Cells (2019) (9)
- An Omics Perspective on Candida Infections: Toward Next-Generation Diagnosis and Therapy (2016) (9)
- Designing the Next Generation of Vaccines: Relevance for Future Pandemics (2020) (9)
- sTREM-1, sIL-2Rα, and IL-6, but not sCD163, might predict sepsis in polytrauma patients: a prospective cohort study (2017) (9)
- Seasonal and Nonseasonal Longitudinal Variation of Immune Function (2021) (9)
- Genome-Wide Association Study Identifies Novel Colony Stimulating Factor 1 Locus Conferring Susceptibility to Cryptococcosis in Human Immunodeficiency Virus-Infected South Africans (2020) (9)
- Involvement of matrix metalloproteinases in chronic Q fever. (2017) (9)
- Autophagy suppresses host adaptive immune responses toward Borrelia burgdorferi (2016) (9)
- Minimal Sex-Differential Modulation of Reactivity to Pathogens and Toll-Like Receptor Ligands following Infant Bacillus Calmette–Guérin Russia Vaccination (2017) (9)
- Beneficial non-specific effects of live vaccines against COVID-19 and other unrelated infections (2022) (9)
- Toll-like receptor 4 polymorphisms in dengue virus-infected children. (2011) (9)
- Genetic variation in Interleukin-32 influence the immune response against New World Leishmania species and susceptibility to American Tegumentary Leishmaniasis (2020) (9)
- Efficacy of BCG Vaccination Against Respiratory Tract Infections in Older Adults During the Coronavirus Disease 2019 Pandemic (2022) (9)
- High-dose vitamin D3 supplementation is a requisite for modulation of skin-homing markers on regulatory T cells in HIV-infected patients. (2012) (9)
- Trained immunity-related vaccines: innate immune memory and heterologous protection against infections. (2022) (9)
- Multivariate inference of pathway activity in host immunity and response to therapeutics (2014) (9)
- NOD2/CARD15 modulates specific Toll-like receptor pathways for the induction of cytokine release (2006) (9)
- The MTHFD1 c.1958 G>A polymorphism and recurrent spontaneous abortions (2011) (9)
- Influence of endogenous pro-inflammatory cytokines on neutrophil-mediated damage of Candida albicans pseudohyphae, quantified in a modified tetrazolium dye assay. (2005) (9)
- Heme induces innate immune memory (2019) (9)
- A missense mutation underlies defective SOCS4 function in a family with autoimmunity (2015) (9)
- Trained immunity: implications for vaccination. (2022) (9)
- BCG vaccination in healthcare providers and the protection against COVID-19. (2020) (9)
- Long-term treated HIV infection is associated with platelet mitochondrial dysfunction (2021) (9)
- The influence of the gut microbiome on BCG-induced trained immunity (2021) (9)
- Treatment of candidiasis: insights from host genetics (2012) (9)
- Soluble TLR2 and 4 concentrations in cerebrospinal fluid in HIV/SIV-related neuropathological conditions (2017) (8)
- A Targeted Association Study of Immunity Genes and Networks Suggests Novel Associations with Placental Malaria Infection (2011) (8)
- High-Mobility Group Nucleosome-Binding Protein 1 as Endogenous Ligand Induces Innate Immune Tolerance in a TLR4-Sirtuin-1 Dependent Manner in Human Blood Peripheral Mononuclear Cells (2018) (8)
- CXCL9, a promising biomarker in the diagnosis of chronic Q fever (2017) (8)
- Recombination networks as genetic markers in a human variation study of the Old World (2012) (8)
- TLR1 polymorphisms in Europeans and spontaneous pregnancy loss. (2012) (8)
- A role for TLR1, TLR2 and NOD2 in cytokine induction by Bacteroides fragilis. (2012) (8)
- Natural resistance against infections: focus on COVID-19 (2021) (8)
- Toward personalized immunotherapy in sepsis: The PROVIDE randomized clinical trial (2022) (8)
- Immunomodulation by n-3 polyunsaturated fatty acids. (1999) (8)
- Anti-TNF therapy and plasma HDL cholesterol concentration. (2005) (8)
- IFN-gamma is not induced through increased plasma concentrations of interleukin-12/interleukin-18 during human endotoxemia. (2005) (8)
- A joint effort: The interplay between the innate and the adaptive immune system in Lyme arthritis (2020) (8)
- Comparative host transcriptome in response to pathogenic fungi identifies common and species-specific transcriptional antifungal host response pathways (2020) (8)
- Immune responses in relation to the type and time of thermal injury: an experimental study. (2015) (8)
- Gamma-Irradiated Bacille Calmette-Guérin Vaccination Does Not Modulate the Innate Immune Response during Experimental Human Endotoxemia in Adult Males (2015) (8)
- Gene expression signatures identify biologically and clinically distinct tuberculosis endotypes (2020) (8)
- DNA Synthesis Is Activated in Mosquitoes and Human Monocytes During the Induction of Innate Immune Memory (2018) (8)
- Urate-induced epigenetic modifications in myeloid cells (2021) (8)
- Expansion of mutation-driven haematopoietic clones is associated with insulin resistance and low HDL-cholesterol in individuals with obesity (2021) (8)
- Firing Up Glycolysis: BCG Vaccination Effects on Type 1 Diabetes Mellitus (2018) (8)
- Adjuvant interferon-gamma immunotherapy in a patient with progressive cerebral Nocardia abscesses. (2017) (8)
- Oncogene-induced maladaptive activation of trained immunity in the pathogenesis and treatment of Erdheim-Chester disease. (2021) (8)
- Immune Parameters for Diagnosis and Treatment Monitoring in Invasive Mold Infection (2019) (8)
- Thyrotrophin and thyroxine support immune homeostasis in humans (2021) (8)
- Steroid hormone-related polymorphisms associate with the development of bone erosions in rheumatoid arthritis and help to predict disease progression: Results from the REPAIR consortium (2019) (8)
- Correction: Corrigendum: IL-37 protects against obesity-induced inflammation and insulin resistance (2015) (8)
- The Immunological Factors Predisposing to Severe Covid-19 Are Already Present in Healthy Elderly and Men (2021) (7)
- Pulmonary infection, and not systemic inflammation, accounts for increased concentrations of exhaled nitric oxide in patients with septic shock (2013) (7)
- Differential In Vitro Cytokine Induction by the Species of Cryptococcus gattii Complex (2018) (7)
- Skin lesions on the foot. (2003) (7)
- Hydroxychloroquine inhibits trained immunity - implications for COVID-19 (2020) (7)
- The influence of dietary fish-oil supplementation on cutaneous Leishmania amazonensis infection in mice. (2002) (7)
- Modulation of inflammatory cytokine production by parenteral lipid emulsions. (2005) (7)
- Deletion of hematopoietic Dectin-2 or CARD9 does not protect against atherosclerotic plaque formation in hyperlipidemic mice (2019) (7)
- Modulation of LPS-, PHA- and M. tuberculosis-mediated cytokine production by pentoxifylline and thalidomide. (2000) (7)
- Randomized clinical trials of COVID-19 vaccines: do adenovirus-vector vaccines have beneficial non-specific effects? (2023) (7)
- Human Newborn Monocytes Demonstrate Distinct BCG-Induced Primary and Trained Innate Cytokine Production and Metabolic Activation In Vitro (2021) (7)
- Immune memory in individuals with COVID-19 (2021) (7)
- Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine (2021) (7)
- Reply to: ‘Lack of evidence for intergenerational inheritance of immune resistance to infections’ (2022) (7)
- PTEN Hamartoma Tumor Syndrome and Immune Dysregulation (2018) (7)
- Interplay between thyroid cancer cells and macrophages: effects on IL-32 mediated cell death and thyroid cancer cell migration (2019) (7)
- HDAC inhibitors modulate innate immune responses to micro‐organisms relevant to chronic mucocutaneous candidiasis (2018) (7)
- Netea, M. G. et al. NOD2 3020insC mutation and the pathogenesis of Crohn's disease: impaired IL-1 production points to a loss-of-function phenotype. Neth. J. Med. 63, 305-308 (2005) (7)
- Interleukin-1 receptor-associated kinase 4 links innate immunity to the pathogenesis of rheumatoid arthritis. (2009) (7)
- Association of Mal/TIRAP S180L variant polymorphism with decreased infection risk in patients with advanced HIV-1 infection. (2012) (7)
- The gut microbiome as mediator between diet and its impact on immune function (2021) (7)
- Oxidation of low-density lipoproteins by acellular components of Chlamydia pneumoniae. (2000) (7)
- A role for TLR10 in obesity and adipose tissue morphology (2018) (7)
- Immunogenicity of the Q fever skin test. (2014) (7)
- Predicting biological age based on the BBMRI-NL 1H-NMR metabolomics repository (2019) (7)
- Understanding the increased risk of infections in diabetes: innate and adaptive immune responses in type 1 diabetes. (2021) (7)
- TNFα AND IL-1β EXERT NO DIRECT VASOACTIVITY IN HUMAN ISOLATED RESISTANCE ARTERIES (2002) (7)
- Primary immunodeficiencies in cytosolic pattern‐recognition receptor pathways: Toward host‐directed treatment strategies (2020) (7)
- Sex-biased patterns shaped the genetic history of Roma (2020) (7)
- for the Induction of Cytokine Release Domain-2 Modulates Specific TLR Pathways Nucleotide-Binding Oligomerization (2005) (7)
- Reactivation of BCG vaccination scars after vaccination with mRNA-Covid-vaccines: two case reports (2021) (7)
- Early versus late BCG vaccination in HIV-1-exposed infants in Uganda: study protocol for a randomized controlled trial (2017) (7)
- The effects of in vivo B-cell depleting therapy on ex-vivo cytokine production. (2013) (7)
- Clonal Hematopoiesis Is Associated With Low CD4 Nadir and Increased Residual HIV Transcriptional Activity in Virally Suppressed Individuals With HIV (2021) (6)
- Polymorphism in innate immunity genes and susceptibility to recurrent vulvovaginal candidiasis (2009) (6)
- Immune recognition of putative alien microbial structures: Host–pathogen interactions in the age of space travel (2020) (6)
- Resolving trained immunity with systems biology (2021) (6)
- Increased sTREM-1 plasma concentrations are associated with poor clinical outcomes in patients with COVID-19 (2021) (6)
- Genetic variation of TLR2 and TLR4 among the Saudi Arabian population: insight into the evolutionary dynamics of the Arabian Peninsula. (2013) (6)
- Toll-Like Receptor / T-Helper Bias From the Th 1 / Th 2 Paradigm towards a (2005) (6)
- Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling (2021) (6)
- BMT decreases HFD-induced weight gain associated with decreased preadipocyte number and insulin secretion (2017) (6)
- Evolution of cytokine production capacity in ancient and modern European populations (2021) (6)
- Discerning divergent tuberculosis endotypes: A meta-analysis and systematic review of individual patient data (2020) (6)
- Lung Epithelial Signaling Mediates Early Vaccine-Induced CD4+ T Cell Activation and Mycobacterium tuberculosis Control (2021) (6)
- Host-microbe interactions in stem cell transplantation; recognizing Candida in infection and inflammation (2010) (6)
- Impact of rare and common genetic variation in the interleukin-1 pathway on human cytokine responses (2020) (6)
- Plasmodium falciparum induces trained innate immunity (2019) (6)
- The Impact of Central and Peripheral Cyclooxygenase Enzyme Inhibition on Exercise-Induced Elevations in Core Body Temperature. (2017) (6)
- Toll-Like Receptors and Inflammasomes (2011) (6)
- The effect of BCG vaccination on alveolar macrophages obtained from induced sputum from healthy volunteers. (2020) (6)
- Long-Lasting Transcriptional Changes in Circulating Monocytes of Acute Q Fever Patients (2019) (6)
- Neutrophils differentially attenuate immune response to Aspergillus infection through complement receptor 3 and induction of myeloperoxidase (2018) (6)
- Fusarium ramigenum, a novel human opportunist in a patient with common variable immunodeficiency and cellular immune defects: case report (2016) (6)
- Subtle immunodeficiencies in nodular–bronchiectatic Mycobacterium avium complex lung disease (2020) (6)
- Mucositis: from febrile neutropenia to febrile mucositis (2009) (6)
- Toward Identification of the Genetic Risk Profile for Cryptococcal Disease in HIV-Infected Patients (2013) (6)
- Antifungal innate immunity: recognition and inflammatory networks (2014) (6)
- Trained immunity — basic concepts and contributions to immunopathology (2022) (6)
- Correction: Corrigendum: Inter-individual variability and genetic influences on cytokine responses to bacteria and fungi (2016) (5)
- Inflammatory arthritis in caspase-1 gene deficient mice: Contribution of proteinase 3 for caspase-1-independent production of bioactive IL-1 β (2011) (5)
- Genomics of Mesolithic Scandinavia reveal colonization routes and high-latitude adaptation (2017) (5)
- The role of sirtuin 1 on the induction of trained immunity. (2021) (5)
- A prospective observational cohort study to identify inflammatory biomarkers for the diagnosis and prognosis of patients with sepsis (2021) (5)
- Invasive fungal infection in an elderly patient with defective inflammatory macrophage function. (2011) (5)
- Interferon-γ and CXCL10 responses related to complaints in patients with Q fever fatigue syndrome (2018) (5)
- Immune defects in patients with pulmonary Mycobacterium abscessus disease without cystic fibrosis (2020) (5)
- B. burgdorferisensu lato-induced inhibition of antigen presentation is mediated by RIP1 signaling resulting in impaired functional T cell responses towards Candida albicans. (2020) (5)
- SAT0025 Shift in Genetic Composition of an IL-32 Promoter Polymorphism Resuls in a Higher Cytokine Production in RA Patients (2015) (5)
- An Explorative Study on Monocyte Reprogramming in the Context of Periodontitis In Vitro and In Vivo (2021) (5)
- An Exaggerated Monocyte-Derived Cytokine Response to Candida Hyphae in Patients With Recurrent Vulvovaginal Candidiasis (2020) (5)
- Clone expansion of mutation-driven clonal hematopoiesis is associated with aging and metabolic dysfunction in individuals with obesity (2021) (5)
- IL-1β processing in mechanical ventilation-induced inflammation is dependent on neutrophil factors rather than caspase-1 (2013) (5)
- Evidence for the heterologous benefits of prior BCG vaccination on COVISHIELD™ vaccine-induced immune responses in SARS-CoV-2 seronegative young Indian adults (2022) (5)
- IL-10 and Regulatory T Cells through Induction Candida albicans against Toll-Like Receptor 2 Suppresses Immunity (2004) (5)
- Author Correction: Trained immunity, tolerance, priming and differentiation: distinct immunological processes (2021) (5)
- Inflammatory Protein Profiles in Plasma of Candidaemia Patients and the Contribution of Host Genetics to Their Variability (2021) (5)
- A Multidisciplinary Approach to Fungal Infections: One-Year Experiences of a Center of Expertise in Mycology (2020) (5)
- 12: IL-37 protects against obesity-induced inflammation and insulin resistance (2013) (5)
- Polymorphisms in autophagy genes and active pulmonary tuberculosis susceptibility in Romania (2017) (5)
- Plasma metabolome predicts trained immunity responses after antituberculosis BCG vaccination (2022) (4)
- Immunologic defects in severe mucocutaneous HSV-2 infections: Response to IFN-γ therapy. (2016) (4)
- Serum Lipoprotein(a) is Increased in Hypertensive NIDDM Patients (1995) (4)
- Il-18 Binding Protein: A Novel Biomarker In Obesity-Related Atherosclerosis That Modulates Lipoprotein Metabolism (2019) (4)
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- Efficacy and safety of early soluble urokinase plasminogen receptor plasma-guided anakinra treatment of COVID-19 pneumonia: A subgroup analysis of the SAVE-MORE randomised trial (2022) (1)
- Toll-Like Receptor 2 Suppresses Immunity (2004) (1)
- OP0017 VALIDATION OF GWAS-IDENTIFIED VARIANTS FOR ANTI-TNF DRUG RESPONSE IN RHEUMATOID ARTHRITIS: A META-ANALYSIS OF THREE LARGE COHORTS (2021) (1)
- BCG-induced trained immunity enhances acellular pertussis vaccination responses in an explorative randomized clinical trial (2022) (1)
- Circulating interleukin-38 concentrations in healthy adults (2022) (1)
- Latent autoimmune diabetes of the adult : epidemiology in the Netherlands (2002) (1)
- HIV-linked gut dysbiosis associates with cytokine production capacity in viral-suppressed people living with HIV (2022) (1)
- The Genetic Risk for COVID-19 Severity Is Associated With Defective Immune Responses (2022) (1)
- ANTI-INFLAMMATORY THERAPY WITH TNF-ALPHA INHIBITORS IMPROVES HDL-CHOLESTEROL ANTI-ATHEROGENIC CAPACITY IN RHEUMATOID ARTHRITIS PATIENTS (2008) (1)
- TH17 cells boosted by nanoparticle-bound fungal motifs (2022) (1)
- Trained immunity, tolerance, priming and differentiation: distinct immunological processes (2020) (1)
- Impact of Human Genetic Variation on C-Reactive Protein Concentrations and Acute Appendicitis (2022) (1)
- An integrative model of cardiometabolic traits identifies two types of metabolic syndrome (2021) (1)
- Human variation in population-wide gene expression data predicts gene perturbation phenotype (2022) (1)
- Cytomegalovirus (CMV) infection accelerates the development of atherosclerosis in apolipoproteinE (apoE) knock-out mice (2000) (1)
- The epigenetic ghost of infections past (2021) (1)
- SARS-CoV-2 RNA in exhaled air of hospitalized COVID-19 patients (2022) (1)
- The discriminative capacity of soluble Toll-like receptor (sTLR)2 and sTLR4 in inflammatory diseases (2014) (1)
- Bacillus Calmette-Guerin vaccine to reduce COVID-19 infections and hospitalisations in healthcare workers: a living systematic review and prospective ALL-IN meta-analysis of individual participant data from randomised controlled trials (2022) (1)
- The C-Type Lectin Receptor CLECSF 8 / CLEC 4 D Is a Key Component of Anti-Mycobacterial Immunity Graphical (2015) (1)
- G polymorphism and mucosal expression of dectin-1 in inflammatory bowel disease (2009) (1)
- Short Report: Toll-Like Receptor 4 Polymorphisms in Dengue Virus-Infected Children (2011) (1)
- No Impact of Dectin-1 Polymorphism Y238X On the Outcome of Hematopoietic Stem Cell Transplantation, but a Role for Candida in Acute Graft-Versus-Host Disease. (2009) (1)
- Prehydration shifts the cytokine response towards a more anti-inflammatory balance during human endotoxemia (2005) (1)
- Author Correction: Gut microbiome-mediated metabolism effects on immunity in rural and urban African populations (2021) (1)
- THE EFFECT OF THE MEASLES, MUMPS AND RUBELLA VACCINE ON INNATE AND ADAPTIVE IMMUNE RESPONSES IN PERSONS RECEIVING A SARS-COV-2 mRNA VACCINE.A SUB-STUDY OF THE CROWN CORONATION TRIAL (2022) (0)
- Effects of Bacillus Calmette-Guérin (BCG) vaccination at birth on T and B lymphocyte subsets: Results from a clinical randomized trial (2017) (0)
- GWAS-Identified Variants for Obesity Do Not Influence the Risk of Developing Multiple Myeloma: A Population-Based Study and Meta-Analysis (2023) (0)
- Differences in anti-viral immune responses in individuals of Indian and European origin: relevance for the COVID-19 pandemic (2022) (0)
- Rewiring of glucose metabolism defines trained immunity induced by oxidized low-density lipoprotein (2020) (0)
- Individualized significance of the −251 A/T single nucleotide polymorphism of interleukin-8 in severe infections (2016) (0)
- Implications of Non-Specific Effects for Testing, Approving, and Regulating Vaccines (2023) (0)
- OP0221 OLIGOMERIC S100A4 INDUCES MONOCYTE INNATE IMMUNE MEMORY (2019) (0)
- Host genetic variants regulates CCR5 expression on immune cells: a study in people living with HIV and healthy controls (2022) (0)
- Human Dectin-1 Deficiency Causes Mucocutaneous Fungal Infections (2008) (0)
- Correction to: Rewiring of glucose metabolism defines trained immunity induced by oxidized low-density lipoprotein (2020) (0)
- Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine (2021) (0)
- Interplay between thyroid cancer cells and macrophages: effects on IL-32 mediated cell death and thyroid cancer cell migration (2019) (0)
- A study protocol of external validation of eight COVID-19 prognostic models for predicting mortality risk in older populations in a hospital, primary care, and nursing home setting (2023) (0)
- Do GWAS-Identified Risk Variants for Chronic Lymphocytic Leukemia Influence Overall Patient Survival and Disease Progression? (2023) (0)
- Abstract 19220: Hepatic Steatosis is Independently Associated With an Increased Vascular Stiffness in Overweight Subjects (2015) (0)
- Deletion of hematopoietic Dectin-2 or CARD9 does not protect against atherosclerotic plaque formation in hyperlipidemic mice (2019) (0)
- Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases (2019) (0)
- Genetic variant in IL-32 is associated with the ex vivo cytokine production of anti-TNF treated PBMCs from rheumatoid arthritis patients (2018) (0)
- Corrigendum: ACTIVATE-2: A double-blind randomized trial of BCG vaccination against COVID-19 in individuals at risk (2022) (0)
- 62. Cytokine production by mononuclear cells of patients with familial hypercholesterolemia (1997) (0)
- Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity (2020) (0)
- The 2000HIV study: Design, multi-omics methods and participant characteristics (2022) (0)
- Correction to: Origins, admixture and founder lineages in European Roma (2021) (0)
- Systemic inflammation impairs human myelopoiesis and interferon I responses (2022) (0)
- S. cerevisiae chitin drives trained immunity during cross-talk with microbiota (2015) (0)
- Author response for "Limited impact of impaired awareness of hypoglycaemia and severe hypoglycaemia on inflammatory profile in people with type 1 diabetes" (2020) (0)
- Author Correction: Engineering cytokine therapeutics (2023) (0)
- Diversity and Ecology of Caudoviricetes Phages with Genome Terminal Repeats in Fecal Metagenomes from Four Dutch Cohorts (2022) (0)
- Microbiome-Related Indole and Serotonin Metabolites are Linked to Inflammation and Psychiatric Symptoms in People Living with HIV (2022) (0)
- Genome-Wide Association Study Reveals CLEC7A and PROM1 as Potential Regulators of Paracoccidioides brasiliensis-Induction of Cytokine Production in Peripheral Blood Mononuclear Cells (2023) (0)
- vaccination at birth and antibody responses to childhood vaccines. A randomised clinical trial (2018) (0)
- Choice of DNA extraction method affects stool microbiome recovery and subsequent phenotypic association analyses (2022) (0)
- Recombination networks as genetic markers in a human variation study of the Old World (2011) (0)
- Author Correction: Heritability estimates for 361 blood metabolites across 40 genome-wide association studies (2020) (0)
- Deconvolution of bulk blood eQTL effects into immune cell subpopulations (2020) (0)
- Author Correction: Transmission of trained immunity and heterologous resistance to infections across generations (2023) (0)
- Exploratory analysis of interleukin‐38 in hospitalized COVID‐19 patients (2022) (0)
- NFKB2 polymorphisms associate with the risk of developing rheumatoid arthritis and response to TNF inhibitors: Results from the REPAIR consortium (2020) (0)
- Kinase Signaling Phagosomes via Targeting Dectin-1/Syk Aspergillus fumigatus Recruitment in Corticosteroids Block Autophagy Protein (2013) (0)
- Complement activation in severely ill patients with sepsis: no relationship with inflammation and disease severity (2023) (0)
- Systematic analysis of relationships between plasma branched-chain amino acid concentrations and cardiometabolic parameters: an association and Mendelian randomization study (2022) (0)
- BCG vaccination of healthcare workers does not reduce SARS-CoV-2 infections nor infection severity or duration: a randomised placebo-controlled trial (2022) (0)
- Novel insights into the biology of interleukin-32 (2013) (0)
- P078 A genetic variant of IL-32 is associated with the ex vivo cytokine production of ANTI-TNF treated pbmcs isolated from rheumatoid arthritis patients (2018) (0)
- Long-term effects of a short-term high-fat challenge on innate immune cell function in humans (2021) (0)
- Soluble TLR2 and 4 concentrations in cerebrospinal fluid in HIV/SIV-related neuropathological conditions (2016) (0)
- Author Correction: Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome (2018) (0)
- Antibody neutralization of microbiota-derived circulating peptidoglycan dampens inflammation and ameliorates autoimmunity (2019) (0)
- Novel PI 3 K c Mutation in a 44-Year-Old Man with Chronic Infections and Chronic Pelvic Pain (2013) (0)
- Comprehensive phenotyping of circulating immune cell subsets in people living with HIV. (2022) (0)
- Novel PI3Kc Mutation in a 44-Year-Old Man with Chronic Infections and Chronic Pelvic Pain (2019) (0)
- Author Correction: Sex-biased patterns shaped the genetic history of Roma (2020) (0)
- A genome-wide functional genomics approach uncovers genetic determinants of immune phenotypes in type 1 diabetes (2022) (0)
- ILDS Newsletter No. 20 (2011) (0)
- INHIBITION OF CHRONIC DESTRUCTIVE ARTHRITIS USING A NATURALLY OCCURRING TLR4 ANTAGONIST: 118 (2006) (0)
- Discussion following lecture by T.H.M. Ottenhoff (2004) (0)
- Assessment of Aerosol Generating Events During the Nasopharyngeal Swabbing for SARS-CoV-2 Detection (2021) (0)
- hosted at the Radboud Repository of the (2017) (0)
- Skin lesions on the foot. Reply (2003) (0)
- Immunisation for old adults in Europe: scientific and social strategies FEAM (2022) (0)
- Different pathogenic stimuli induce specific metabolic rewiring in human monocytes (2016) (0)
- Differences in the inflammatory proteome of East African and Western European adults and associations with environmental and dietary factors (2022) (0)
- Author Correction: Assessment of the frequency of coughing and sneezing triggered by nasopharyngeal swabbing in the pandemic setting (2022) (0)
- Mammalian Innate Host Defense Interplay between Candida albicans and the (2012) (0)
- THU0142 High Similarity between ex-vivo Inhibited Cytokine Profiling by Golimumab and Adalimumab as A Putative Explanation for Inferior Treatment Response To Golimumab after Adalimumab Failure in Rheumatoid Arthritis (2016) (0)
- Preferential production of interleukin-6 (IL-6) and IL-1 beta by murine peritoneal macrophages exposed to IL-18: No role for TNF and lymphotoxin-alpha (1998) (0)
- PS2 - 9. Effect of B- and T-cell deficiency on obesity-induced inflammation and insulin resistance (2011) (0)
- Evolutionary Trajectories of Complex Traits in European Populations of Modern Humans (2022) (0)
- Strains of Probiotics Bifidobacterium breve and Lactobacillus and Induction of Cytokine Profile by Differential Toll-Like Receptor Recognition (2011) (0)
- Proinflammatory cytokine responses in patients with psoriasis (2014) (0)
- MAP 3 K 8 ( TPL 2 / COT ) Affects Obesity-Induced Adipose Tissue Inflammation without Systemic Effects in Humans and in Mice (2017) (0)
- Letter by Popa and Netea regarding article, "Angiotensin-converting enzyme inhibition improves vascular function in rheumatoid arthritis". (2008) (0)
- True autosomal dominant inheritance of familial mediterranean fever caused by a mutation in exon 8 of the MEFV gene (2012) (0)
- Reduced CXCL1 production by endogenous IL-37 expressing dendritic cells does not affect T cell activation (2021) (0)
- Primes TLR Cytokine Candida albicans (2013) (0)
- Increased Soluble lnterleukin-2 Receptor Concentrations in Patients with Insulin» dependent Diabetes Mellitus The central pathogenetic event in insulin- dependent (Type 1) diabetes mellitus (2017) (0)
- Circulating cytokines and LPS-induced cytokine production in patients with essential hypertension (EH) (1998) (0)
- Abstract: P731 DIFFERENTIAL ACCUMULATION OF OXIDIZED LDL IN M1 AND M2 MACROPHAGES (2009) (0)
- WITHDRAWN: The role of the inflammasome and toll-like receptor signaling the pathogenesis of infection with Mycobacterium tuberculosis (2012) (0)
- Plasma obtained during human endotoxemia increases endothelial permeability in vitro (2006) (0)
- Genetics of Chronic Mucocutaneous Candidiasis (2017) (0)
- Molecular Medicine p 38 c / p 38 d regulate C . albicans infection (2018) (0)
- A novel function of the Crohn’s disease—Associated Nod2 mutant 1007 fs in the regulation of human IL10 gene transcription (2009) (0)
- Pathogenicity and Commensalism Recognition Contribute to Fungal Differential IL-17 Production and Mannan (2017) (0)
- THE INFLUENCE OF DIETARY FISH-OIL SUPPLEMENTATION ON CUTANEOUS INFECTION IN MICE (2002) (0)
- B3: Bacteria, Brain & Behaviour (2015) (0)
- OR04-2 Aldosterone Induces Trained Immunity via Fatty Acid Synthesis (2019) (0)
- Differential effects of glucose on the production of tumor necrosis factor and interleukin-1 beta (1999) (0)
- Causal relationships between gut microbiome, short-chain fatty acids and 1 metabolic diseases 2 (2019) (0)
- PS4 - 4. Proteinase 3: a new link between inflammation, obesity and Type 2 Diabetes (2013) (0)
- Apoptosis of neutrophils, expression of TREM-1 on neutrophils and IL-17 responses in experimental burn in injury are related to the type and time of burn exposure (2012) (0)
- Thr300Ala ATG16L1 polymorphism influences susceptibility to and the prognosis of epithelial cell derived thyroid carcinoma (2011) (0)
- Release of Constitutive IL-1 Soluble Murine IL-1 Receptor Type I Induces (1999) (0)
- Host Genomics and Bacterial Infections (2010) (0)
- Defective acute inflammation in Crohn's disease (2006) (0)
- Role of tumour necrosis factor α in intra‐abdominal abscesses caused by Candida albicans (2000) (0)
- PS1 - 1. TLR-3 is highly expressed in human adipocytes, but deficiency of TLR3 does not protect against obesity-induced inflammation and insulin resistance in mice (2013) (0)
- Title: Integration of Candida albicans -induced single-cell gene expression data 1 and circulatory protein concentrations reveal genetic regulators of inflammation 2 (2022) (0)
- Proinflammatory Cytokine Responses Neutrophil-Mediated Inhibition of (0)
- Host Defense Relatives: Principles of Pathogenesis and Black Yeasts and Their Filamentous (2014) (0)
- In the News (2008) (0)
- Integration of similar to 10,000 metabolite features with genotype data and immune phenotypes reveals genetic determinants and common regulatory modules (2019) (0)
- Macrophage heterogeneity in human carotid artery atherosclerotic plaques: identification of novel markers for M1 and M2 that are independent of the activation status (2016) (0)
- Substance use, Unlike Dolutegravir, is Associated with Mood Symptoms in People Living with HIV (2021) (0)
- Contents: Eur. J. Immunol. 4'16. (2016) (0)
- RECOMBINANT GRANULOCYTE COLONY‐STIMULATING FACTOR PROTECTS AGAINST CANDIDA SEPTICEMIA IN MICE: 316 (1997) (0)
- Mechanisms of allergy/immunology Shared DNAmethylation signatures in childhood allergy: The MeDALL study (2021) (0)
- POS0492 MALADAPTIVE ACTIVATION OF TRAINED IMMUNITY IN THE PATHOGENESIS AND TREATMENT OF GIANT CELL ARTERITIS (2022) (0)
- processing and release of IL-1{beta} in monocytes and macrophages Differential requirement for the activation of the inflammasome for (2009) (0)
- Shifts , Aneuploidy , and Loss of Heterozygosity Rapid Mechanisms for Generating Genome Diversity : Whole Ploidy (2014) (0)
- processing and release of IL-1 Differential requirement for the activation of the inflammasome for (2009) (0)
- FACTOR-a AND INTERLEUKIN 1 RECEPTOR ANTAGONIST IN NEWLY DIAGNOSED INSULIN-DEPENDENT DIABETES MELLITUS: COMPARISON TO LONG-STANDING DIABETES AND HEALTHY INDIVIDUALS (2019) (0)
- Lung epithelial signaling mediates early vaccine-induced CD4+ T cell activation and Mtb control (2021) (0)
- CHAPTER 110 – Host Genomics and Bacterial Infections (2009) (0)
- Correction for Bekkering et al., “In Vitro Experimental Model of Trained Innate Immunity in Human Primary Monocytes” (2017) (0)
- Synergistic effects of tumour necrosis factor α and lymphotoxin α during lethal endotoxaemia (2000) (0)
- THE EUROPEAN SHOCK SOCIETY MEETS THE IMMUNOSEP CONSORTIUM FOR PERSONALIZED SEPSIS TREATMENT (2022) (0)
- Contents: Eur. J. Immunol. 7'16. (2016) (0)
- Caspase-1, but not ASC or NLRP3 inflammasome components, mediates IL-1beta activation and antifungal defense in disseminated candidiasis (2009) (0)
- University of Groningen Exposure to Candida albicans Polarizes a T-Cell Driven Arthritis Model towards Th17 Responses, Resulting in a More Destructive Arthritis Marijnissen, Renoud (2012) (0)
- University of Groningen Macrophage Specific Caspase-1/11 Deficiency Protects against Cholesterol Crystallization and Hepatic Inflammation in Hyperlipidemic Mice Hendrikx, (2013) (0)
- Dominant drivers of the human plasma metabolome (2021) (0)
- Author response: Reprogramming of bone marrow myeloid progenitor cells in patients with severe coronary artery disease (2020) (0)
- A comprehensive assessment of the interplay between the thyroid function and the immune system: results from the Human Functional Genomics Project (2019) (0)
- Age-specific effects of Bacille Calmette-Guérin (BCG) vaccine on primary and trained innate cytokine production by human newborn monocytes in vitro are accompanied by distinct metabolic activation (2018) (0)
- IL-1-8 IL-1β and the development of Th17 responses (2010) (0)
- University of Southern Denmark β-Glucan-Induced Trained Immunity Protects against Leishmania braziliensis Infection (2019) (0)
- Borrelia burgdorferi inhibits NADPH-mediated reactive oxygen species production through the mTOR pathway. (2022) (0)
- Cytokines and cytokine receptors: Physiology and pathological disorders: Edited by Constatin A. Bona and Jean-Pierre Revillard Martin Dunitz 2001, ISBN 9057026341, Hardback, 592 pages, US$135 (2003) (0)
- 102. Dexamethasone, but not chlorpromazine, decreases ex-vivo tumor necrosis factor-? and interleukin-1? production in human volunteers (1997) (0)
- Therapeutic Prospects for Harnessing Innate Immunity against Fungi (2008) (0)
- The galactosaminogalactan ao Aspergillus fumigatus is a major anti-inflammatory molecule tha induces IL1 receptors antagonist (2013) (0)
- A Weakened Immune Response to Synthetic Exo-Peptides Predicts a Potential Biosecurity Risk in the Retrieval of Exo-Microorganisms (2020) (0)
- Plasma proteins as a predictor of chronological age in people living with HIV: a cross-sectional study (2022) (0)
- Positive selection analysis in european an rroma populations identifies convergent evolution on TLR1/TLR6/TLR10 pattern recognition system (2013) (0)
- Hepatitis C Virus Reactivation Following COVID-19 Vaccination – A Case Report [Corrigendum] (2021) (0)
- Immunometabolic circuits in host defense (2016) (0)
- Erratum to Letter to the Editor: “Anti-TNF therapy and plasma HDL cholesterol concentration” [Atherosclerosis 182 (2005) 375] (2006) (0)
- Long Term Immune and Epigenetic Dysregulation Following COVID-19: The Impact of Anti-IL-1 Treatment in the Post-Acute COVID Syndrome (2022) (0)
- Serum lipoprotein(A) in type II diabetes patients with coronary heart disease (1995) (0)
- Aspergillus Attenuates Distinct Host TLR2 & TLR4 Responses (2008) (0)
- Disease-specific and non-specific ex-vivo stimulation of whole blood for cytokine production. Possible application in the study of tuberculosis (1998) (0)
- Immune responses in relation to the type and time of thermal injury: an experimental study: 12AP4-7 (2014) (0)
- Abnormal Thyroid Function Is Associated With Lymphopenia in Bacterial Sepsis and COVID-19 (2021) (0)
- Inhibition of the cholesterol synthesis pathway prevents trained innate immunity (2016) (0)
- The principal cell surface pattern recognition receptors involved in Candida recognition. (2013) (0)
- Commensal yeast S. cerevisiae trains human monocytes for a heightened cytokine response upon bacterial encounter (2015) (0)
- Mechanisms of Disease (2019) (0)
- A possible role for mitochondrial-derived peptides humanin and MOTS-c in patients with Q fever fatigue syndrome and chronic fatigue syndrome (2019) (0)
- Strain dependent variation of immune responses: how fungal origin and biodiversity shape commensalism or pathogenicity (2013) (0)
- Front & Back Matter (2013) (0)
- Bone marrow transplantation induces changes in the gut microbiota that chronically increase the cytokine response pattern of splenocytes (2022) (0)
- PS15 - 76. The Toll like receptor 3 in adipose tissue determines local inflammation (2011) (0)
- Mediated Pathway - Responses through a Dectin-1/Raf-1 Primes TLR Cytokine Candida albicans (2013) (0)
- The impact of pre-existing thyroid diseases on susceptibility to respiratory infections or self-reported sickness during the SARS-CoV-2 pandemic. (2022) (0)
- Th17 cells and innate immunity (2012) (0)
- monocytes after engagement of various pattern recognition receptors (2014) (0)
- Macrophage Activation Syndrome in Sepsis: Does It Exist and How to Recognize It? (2020) (0)
- P364 OXIDIZED LDL EXPOSURE DECREASES KR ÜPPEL-LIKE FACTOR 2 EXPRESSION AND INCREASES PRO-INFLAMMATORY CAPACITY OF M2 MACROPHAGES (2010) (0)
- [Cytokines and immunotherapy in infectious diseases]. (1999) (0)
- Oral presentations (2009) (0)
- THE ROLE OF OBESITY AND PLASMA ADIPOCYTOKINES IN IMMUNE DYSREGULATION IN SEPSIS PATIENTS (2022) (0)
- The higher interleukin-1 production by LPS-stimulated macrophages of LDL-receptor knock-out mice is a CD11c/CD18-mediated phenomenon (1997) (0)
- Assessment of LC3 I and II levels in PBMCs under starving conditions or pharmacological treatment with 3MA. (2013) (0)
- Maturation Induce Dendritic Cell Migration and Gram-Positive Bacteria in Their Capacity to Discriminates Gram-Negative from TLR 4-Mediated Podosome Loss (2009) (0)
- Late Breaking Abstract - Plasma cells and endothelitis in COVID-19 lung pathology (2020) (0)
- Reply on: Role of Fas/FasL in systemic Candidiasis (2000) (0)
- Assessment of the frequency of coughing and sneezing triggered by nasopharyngeal swabbing in the pandemic setting (2022) (0)
- Immunometabolic Pathwa ys in BCG-Induced Trained Immunity Graphical (2016) (0)
- Mumps immunity on the wane? (2008) (0)
- PS2-26 Crohn’s disease associated ATG16L1 polymorphism modulates cytokine production after NOD2 engagement (2010) (0)
- Blunted IL-17 responses early after advent of multiple injuries (2012) (0)
- Identifying platelet-derived factors as amplifiers of B. burgdorferi-induced cytokine production (2022) (0)
- Complex immunometabolic pathways mediate the interaction between thyroid carcinoma cells and tumor-associated macrophages (2016) (0)
- THU0010 THE ANTI-INFLAMMATORY CYTOKINE INTERLEUKIN 37 IS AN ENDOGENOUS INHIBITOR OF TRAINED IMMUNITY (2019) (0)
- Outcomes of controlled human malaria infection after BCG vaccination (2019) (0)
- Macrophage function in sepsis patients (2018) (0)
- Correction to: Origins, admixture and founder lineages in European Roma (2021) (0)
- Author Correction: Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome (2018) (0)
- INNATE RESPONSES OF KUPFFER CELLS TO C. ALBICANS AND A. FUMIGATUS DO NOT INVOLVE TLR4, BUT SRC MEDIATES CYTOKINE PRODUCTION BY C. ALBICANS CONIDIA: 490 (2004) (0)
- A limited role of cytokine storm and fibrogenesis in COVID-19 related liver injury. (2021) (0)
- Regulatory T cells (PP-045) (2010) (0)
- Running title: Bartonella LPS is a TLR4 antagonist (2007) (0)
- Integration of Candida albicans-induced single-cell gene expression data and secretory protein concentrations reveal genetic regulators of inflammation (2022) (0)
- Normal Host-Fungus Interaction Glycosylation , Cell Wall Integrity , and Are Required for N Candida albicans-Glycosidases of α Endoplasmic Reticulum (2007) (0)
- PS4 - 6. Hepatic vanin-1 is highly induced by PPAR-alpha and a key mediator of hepatic lipid metabolism in the fasted state (2013) (0)
- Fungal chitin induces trained immunity in human monocytes during cross-talk with Saccharomyces cerevisiae (2015) (0)
- 2322 S ) causing congenital hypothyroidism in a Sudanese family : a case report (2019) (0)
- PS2-102. Cross-tolerance and priming between C-type lectin receptors and TLRs (2011) (0)
- Fungal infections 6 Immunotherapeutic approaches to treatment of fungal diseases (2017) (0)
- Chronic Yersiniosis in a Patient With Defects in the Tlr5 and Nod2 Recognition Pathways (2008) (0)
- Role of cytokines of the tumour necrosis factor family in the immune response to disseminated Candida albicans infection (2000) (0)
- Abstract 12533: Mast Cells Induce Vascular Smooth Muscle Cell Apoptosis in Atherosclerotic Plaques via a Toll-Like Receptor 4 Activation Pathway (2010) (0)
- Differential Cytokine Induction by the Species of Cryptococcus gattii Complex (2018) (0)
- To the Editor (2006) (0)
- LPS-Induced Release of IL-1 , IL-1Ra, IL-6, and TNF- in Whole Blood from Patients with Familial Hypercholesterolemia: No Effect of Cholesterol-Lowering Treatment (2017) (0)
- Glutaminolysis and Fumar ate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity Graphical (2016) (0)
- Abstract 15495: Interleukin 18 Binding Protein Predicts Future Cardiovascular Morbidity and Mortality in Subjects Undergoing Coronary Angiography - the Casablanca Cohort (2020) (0)
- Lipofundin® increases in vitro adhesion molecule expression, degranulation and binding capacity of human neutrophils, contrary to Intralipid® and structured Fat Emulsion 73403® (1998) (0)
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- Abstracts of the 15th International Symposium on Infections in the Immunocompromised Host June 22-25, 2008, Thessaloniki, Greece (2008) (0)
- Early An enigma: why vitamin A supplementation does not always reduce mortality even though vitamin A deficiency is associated with increased mortality (2015) (0)
- Development and Validation of SCOPE Score: A Clinical Score to Predict Progression to Severe Respiratory Failure in Hospitalized Patients With COVID-19 Pneumonia (2021) (0)
- PS2-044. Bypassing the inflammasome: crucial role for neutrophil serine proteases in ventilator-induced lung injury (2011) (0)
- P087 The anti-inflammatory cytokine interleukin 37 is an endogenous inhibitor of trained immunity (2019) (0)
- S1191 The Pattern Recognition Receptor Dectin-1 Is Up-Regulated in Active Inflammatory Bowel Disease Without An Association with a Potentially Explanatory Non-Synonymous Polymorphism Within Dectin-1 (2009) (0)
- PS21 - 102. IL-37 protects against obesity-induced inflammation and insulin resistance in mice (2012) (0)
- [Is it possible that BCG vaccine protects against COVID-19?] (2020) (0)
- between treatment and systemic inflammation in acromegaly. (2021) (0)
- Downregulating IL-17 Production Dampens Host Defense by Candida albicans (2010) (0)
- Caspase-1 and ASC but not NLRP3 mediate antifungal defense in candidiasis sepsis (2009) (0)
- TMAO and its precursors in relation to host genetics, gut microbial composition, diet, and clinical outcomes: Meta-analysis of 5 prospective population-based cohorts (2022) (0)
- Gamma-irradiated bacille calmette-guÉrin vaccination does not modulate the innate immune response during experimental human endotoxemia (2015) (0)
- Circulating galectin-3 in infections and non-infectious inflammatory diseases (2013) (0)
- In response to the Letter to the Editor by Ould Setti and Ould Setti RE: ‘Non-specific Effects of vaccines and stunting: Timing May Be Essential’ (2021) (0)
- Microarray analysis of neutrophils subsets during human experimental endotoxemia. (2013) (0)
- Lipopolysaccharide binds and stimulates mononuclear cells before neutralization by circulating lipoproteins can occur (1997) (0)
- P321: PERTURBATIONS IN STIMULUS-INDUCED CYTOKINE RESPONSES IN CHILDREN WITH BCP-ALL (2022) (0)
- Trained immunity by oxidized low-density lipoprotein is defined by reprogramming of glycolytic metabolism in human monocytes (2018) (0)
- Association of autophagy-related 16-like 1 (ATG16L1) gene polymorphism with sepsis severity in patients with sepsis and ventilator-associated pneumonia (2014) (0)
- Genetic and environmental effects on the immune phenotypes in type 1 diabetes (2021) (0)
- 1262 HEMATOPOIETIC CASPASE-1 DEFICIENCY REDUCES HEPATIC INFLAMMATION AND CHOLESTEROL CRYSTALLIZATION IN HYPERLIPIDEMIC MICE (2013) (0)
- Persistent monocyte activation in patients with elevated LDL cholesterol levels during statin treatment (2018) (0)
- Monocyte andmacrophage immunometabolism in atherosclerosis (2017) (0)
- Association of a variable number tandem repeat in the NLRP3 gene in women with susceptibility to RVVC (2016) (0)
- The impact of caspase-12 on susceptibility to candidemia (2011) (0)
- Bacteroides fragilis inhibits Candida albicans induced IL-17 (2011) (0)
- Faculty Opinions recommendation of IGF-2 Preprograms Maturing Macrophages to Acquire Oxidative Phosphorylation-Dependent Anti-inflammatory Properties. (2019) (0)
- Anti-mycobacterial activity correlates with altered DNA methylation pattern in immune cells from BCG-vaccinated subjects (2017) (0)
- The role of inflammation and innate immune cells in young myocardial infarction patients without traditional risk factors (2022) (0)
- Faculty Opinions recommendation of Windborne long-distance migration of malaria mosquitoes in the Sahel. (2019) (0)
- Data driven identification of divergent host immune subgroups in tuberculosis (2020) (0)
- Faculty Opinions recommendation of SDHA gain-of-function engages inflammatory mitochondrial retrograde signaling via KEAP1-Nrf2. (2019) (0)
- Faculty Opinions recommendation of Mass Cytometry Reveals Global Immune Remodeling with Multi-lineage Hypersensitivity to Type I Interferon in Down Syndrome. (2019) (0)
- FunHoMic: A Marie Skłodowska-Curie Innovative Training Network for the study of the Fungus-Host-Microbiota interplay (2021) (0)
- Faculty Opinions recommendation of Programmed 'disarming' of the neutrophil proteome reduces the magnitude of inflammation. (2020) (0)
- No Signs of Neuroin fl ammation in Women With Chronic Fatigue Syndrome or Q Fever Fatigue Syndrome Using the TSPO Ligand [ 11 C]-PK11195 (0)
- Faculty Opinions recommendation of The source of glycolytic intermediates in mammalian tissues. (2021) (0)
- Intensive insulin therapy does not change the inflammatory response in non-diabetic patients undergoing elective coronary artery bypass grafting (2005) (0)
- Faculty Opinions recommendation of PIRs mediate innate myeloid cell memory to nonself MHC molecules. (2020) (0)
- Faculty Opinions recommendation of Nitric Oxide Modulates Metabolic Remodeling in Inflammatory Macrophages through TCA Cycle Regulation and Itaconate Accumulation. (2019) (0)
- Faculty Opinions recommendation of Evolution of antibody immunity to SARS-CoV-2. (2021) (0)
- Faculty Opinions recommendation of Allergoid-mannan conjugates reprogram monocytes into tolerogenic DCs via epigenetic and metabolic rewiring. (2021) (0)
- Author response: An integrative model of cardiometabolic traits identifies two types of metabolic syndrome (2020) (0)
- Clinical and immunological characteristics of patients with pulmonary Mycobacterium abscessus disease without cystic fibrosis (2019) (0)
- Two week interruption of statin therapy results in an exaggerated inflammatory phenotype in young myocardial infarction patients without standard modifiable risk factors (2022) (0)
- Faculty Opinions recommendation of Emerging roles of Dectin-1 in noninfectious settings and in the CNS. (2021) (0)
- Faculty Opinions recommendation of Metabolic regulation of gene expression by histone lactylation. (2019) (0)
- Faculty Opinions recommendation of Pseudomonas aeruginosa Utilizes Host-Derived Itaconate to Redirect Its Metabolism to Promote Biofilm Formation. (2020) (0)
- Faculty Opinions recommendation of A network of macrophages supports mitochondrial homeostasis in the heart. (2020) (0)
- Tryptophan metabolism determines outcome in tuberculous meningitis: a targeted metabolomic analysis (2023) (0)
- Targeted proteomics identifies circulating biomarkers associated with active COVID-19 and post-COVID-19 (2022) (0)
- Clinical implications of host genetic variation and susceptibility to severe or critical COVID-19 (2022) (0)
- Engineering cytokine therapeutics (2023) (0)
- People with HIV have higher percentages of circulating CCR5+ CD8+ T cells and lower percentages of CCR5+ regulatory T cells (2022) (0)
- Deletion of both Dectin-1 and Dectin-2 affects the bacterial but not fungal gut microbiota and susceptibility to colitis in mice (2022) (0)
- Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses (2018) (0)
- Author Correction: Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial (2021) (0)
- Immune cell characteristics and cytokine responses in adult HIV-negative tuberculous meningitis: an observational cohort study (2019) (0)
- Innate Immune Training of Human Macrophages by Cathelicidin Analogs (2022) (0)
- Cytokine Hyperresponsiveness in Children With ETV6::RUNX1-positive Acute Lymphoblastic Leukemia After Challenge With Common Pathogens (2023) (0)
- Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome (2018) (0)
- Differential effects of BCG vaccine on immune responses induced by vi polysaccharide typhoid fever vaccination: an explorative randomized trial (2020) (0)
- Single-cell transcriptomics identifies different immune signatures between macrophage activation-like syndrome and immune paralysis in sepsis (2023) (0)
- Early suPAR-Guided Anakinra Treatment in COVID-19 Pneumonia: Subgroup Analyses and 90-Day Outcomes of the SAVE-MORE Trial (2022) (0)
- PS2 - 2. The interleukin-1 receptor antagonist anakinra improves β-cell function in subjects with impaired glucose tolerance (2013) (0)
- 4 / A genetic and genomics approach identifies novel pathways of human antifungal immune responses (2018) (0)
- BCG vaccination impacts the epigenetic landscape of progenitor cells in human bone marrow (2022) (0)
- BCG Vaccination of Health Care Workers Does Not Reduce SARS-CoV-2 Infections nor Infection Severity or Duration: a Randomized Placebo-Controlled Trial (2023) (0)
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- Opposite effects of Vaccinia and modified Vaccinia Ankara on trained immunity (2019) (0)
- The impact of circadian rhythm on Bacillus Calmette-Guérin vaccination effects on SARS-CoV-2 infections (2023) (0)
- The impact of ADRB2 polymorphisms on immune responses and norepinephrine-induced immunosuppression. (2023) (0)
- Genetic regulators of cytokine responses upon BCG vaccination in children from West Africa. (2023) (0)
- Bermekimab Treatment for Clinical Improvement of Systemic Sclerosis: A Randomized Clinical Trial (2022) (0)
- Targeted plasma proteomics identifies MICA and IL1R1 proteins associated with HIV-1 reservoir size. (2023) (0)
- Influence of Lenvatinib on the Functional Reprogramming of Peripheral Myeloid Cells in the Context of Non-Medullary Thyroid Carcinoma (2023) (0)
- Therapeutic targeting of trained immunity (2019) (0)
- BCG-induced trained immunity enhances acellular pertussis vaccination responses in an explorative randomized clinical trial (2022) (0)
- Bacillus Calmette-Guérin vaccination at birth and in vitro cytokine responses to non-specific stimulation. A randomized clinical trial (2017) (0)
- Intravesical BCG induces a trained immunity phenotype in patients with non-muscle invasive bladder cancer (2021) (0)
- Antifungal immune responses: emerging host–pathogen interactions and translational implications (2018) (0)
- S9.4c Diverse environmental inputs mediate changes in β-glucan exposure at the Candida albicans cell surface thereby influencing tissue colonisation during systemic infection (2022) (0)
- Immunity to fungal infection (PP-092) (2010) (0)
- Differences in Immune Responses in Individuals of Indian and European Origin: Relevance for the COVID-19 Pandemic (2023) (0)
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- Defining trained immunity and its role in health and disease (2020) (0)
- Patients with type 1 diabetes mellitus have impaired IL-1β production in response to Mycobacterium tuberculosis (2017) (0)
- Opposing immunological imprinting of Candida albicans beta-glucan trained immunity and endotoxin tolerance in monocytes. (2015) (0)
- Increased proteinase 3 and neutrophil elastase plasma concentrations are associated with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes (2019) (0)
- Reply to Kontoyiannis. (2011) (0)
- Recurrent candidiasis and early-onset gastric cancer in a patient with a genetically defined partial MYD88 defect (2015) (0)
- An observational study on lifestyle and environmental risk factors in patients with acute appendicitis (2023) (0)
- Interferon gamma-induced protein 10 (IP-10) for the early prognosis of the risk for severe respiratory failure and death in COVID-19 pneumonia (2022) (0)
- Myelomonocytic cells in giant cell arteritis activate trained immunity programs sustaining inflammation and cytokine production. (2023) (0)
- Higher thyroid stimulating hormone leads to cardiovascular disease and an unfavorable lipid profile: EVidence from multi-cohort Mendelian randomization and metabolomic profiling (2021) (0)
- High-throughput proteomic analysis reveals systemic dysregulation in virally suppressed people living with HIV. (2023) (0)
- No Signs of Neuroinflammation in Women With Chronic Fatigue Syndrome or Q Fever Fatigue Syndrome Using the TSPO Ligand [11C]-PK11195 (2021) (0)
- AB0052 ROLE OF TRAINED IMMUNITY AND IMMUNOMETABOLISM IN THE PATHOGENESIS OF ERDHEIM-CHESTER DISEASE (2020) (0)
- The right microbial stimulus can direct innate immune effector cells to specific organ sites to clear pathology (2019) (0)
- Aldosterone induces long-term pro-atherogenic changes in primary human macrophages (2018) (0)
- Genetic diversity of lactase persistence in East African populations (2016) (0)
- The NOD2 receptor is crucial for immune responses towards New World Leishmania species (2017) (0)
- University of Southern Denmark Bacille Calmette-Guérin (BCG) vaccination at birth and antibody responses to childhood vaccines (2017) (0)
- Glutamine Metabolism Supports the Functional Activity of Immune Cells against Aspergillus fumigatus (2022) (0)
- Timing and sequence of vaccination against COVID-19 and influenza (TACTIC): a single-blind, placebo-controlled randomized clinical trial (2023) (0)
- STAT1 gene mutation is not implicated in upper aerodigestive cancers (2012) (0)
- Distinct inactivated bacterial-based immune modulators vary in their therapeutic efficacies for treating disease based on the organ site of pathology (2020) (0)
- Functional and transcriptional differences in monocytes from children with obesity compared to children of healthy weight (2021) (0)
- Sex-specific association between adipose tissue inflammation and vascular and metabolic complications of obesity. (2023) (0)
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