Mina Bissell

Q: What Schools Are Affiliated With Mina Bissell

Mina Bissell is affiliated with the following schools: Kwansei Gakuin University, Baylor College of Medicine, American University of Beirut, University of Copenhagen, University of California, San Francisco, University of Manchester, Harvard University, Radcliffe College, Hokkaido University, University of California, Berkeley, Bryn Mawr College

Mina Bissell's AcademicInfluence.com Rankings

Mina Bissell

Biology

#639

World Rank

#1124

Historical Rank

Cell Biology

#24

World Rank

#27

Historical Rank

biology Degrees

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Biology

Why Is Mina Bissell Influential?

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According to Wikipedia, Mina J. Bissell is an Iranian-American biologist known for her research on breast cancer. In particular, she has studied the effects of a cell's microenvironment, including its extracellular matrix, on tissue function.

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Mina Bissell's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Tumour exosome integrins determine organotropic metastasis (2015) (3223)
Putting tumours in context (2001) (2049)
Reversion of the Malignant Phenotype of Human Breast Cells in Three-Dimensional Culture and In Vivo by Integrin Blocking Antibodies (1997) (1538)
How does the extracellular matrix direct gene expression? (1982) (1456)
Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression (2011) (1341)
Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix (1995) (1255)
Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability (2005) (1231)
Three-dimensional culture models of normal and malignant breast epithelial cells (2007) (1222)
Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells. (1992) (1088)
Pre-metastatic niches: organ-specific homes for metastases (2017) (1084)
Of extracellular matrix, scaffolds, and signaling: tissue architecture regulates development, homeostasis, and cancer. (2006) (1056)
The morphologies of breast cancer cell lines in three‐dimensional assays correlate with their profiles of gene expression (2007) (974)
The Stromal Proteinase MMP3/Stromelysin-1 Promotes Mammary Carcinogenesis (1999) (936)
The perivascular niche regulates breast tumor dormancy (2013) (874)
beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium. (2002) (826)
Cellular changes involved in conversion of normal to malignant breast: importance of the stromal reaction. (1996) (800)
Functional differentiation and alveolar morphogenesis of primary mammary cultures on reconstituted basement membrane. (1989) (737)
Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway (2012) (728)
Control of mammary epithelial differentiation: basement membrane induces tissue-specific gene expression in the absence of cell-cell interaction and morphological polarity (1991) (695)
Reciprocal interactions between beta1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: a different perspective in epithelial biology. (1998) (691)
Matrix Metalloproteinase Stromelysin-1 Triggers a Cascade of Molecular Alterations That Leads to Stable Epithelial-to-Mesenchymal Conversion and a Premalignant Phenotype in Mammary Epithelial Cells (1997) (688)
The organizing principle: microenvironmental influences in the normal and malignant breast. (2002) (613)
Multi‐faceted regulation of cell differentiation by extracellular matrix (1993) (601)
Modeling tissue-specific signaling and organ function in three dimensions (2003) (598)
ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini (2001) (598)
Tissue Geometry Determines Sites of Mammary Branching Morphogenesis in Organotypic Cultures (2006) (582)
Influence of a reconstituted basement membrane and its components on casein gene expression and secretion in mouse mammary epithelial cells. (1987) (561)
Two distinct phases of apoptosis in mammary gland involution: proteinase-independent and -dependent pathways. (2010) (549)
Context, tissue plasticity, and cancer: are tumor stem cells also regulated by the microenvironment? (2005) (526)
Normal and tumor-derived myoepithelial cells differ in their ability to interact with luminal breast epithelial cells for polarity and basement membrane deposition. (2010) (521)
Regulation of in situ to invasive breast carcinoma transition. (2008) (521)
Extracellular matrix-dependent tissue-specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction. (1994) (485)
Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers (2020) (475)
The origin of the myofibroblasts in breast cancer. Recapitulation of tumor environment in culture unravels diversity and implicates converted fibroblasts and recruited smooth muscle cells. (1995) (440)
Coordinated expression of extracellular matrix-degrading proteinases and their inhibitors regulates mammary epithelial function during involution (1992) (437)
The influence of the microenvironment on the malignant phenotype. (2000) (434)
The Influence of Extracellular Matrix on Gene Expression: Is Structure the Message? (1987) (433)
Tissue architecture: the ultimate regulator of breast epithelial function. (2003) (426)
Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance. (2012) (416)
Addressing overdiagnosis and overtreatment in cancer: a prescription for change. (2014) (414)
Laminin mediates tissue-specific gene expression in mammary epithelia (1995) (403)
Isolation, immortalization, and characterization of a human breast epithelial cell line with stem cell properties. (2002) (388)
The interplay of matrix metalloproteinases, morphogens and growth factors is necessary for branching of mammary epithelial cells. (2001) (383)
Organoids: A historical perspective of thinking in three dimensions (2017) (381)
A hierarchy of ECM-mediated signalling regulates tissue-specific gene expression. (1995) (375)
Regulation of mammary gland branching morphogenesis by the extracellular matrix and its remodeling enzymes (2003) (373)
Evidence for a stem cell hierarchy in the adult human breast (2007) (373)
Basal subtype and MAPK/ERK kinase (MEK)-phosphoinositide 3-kinase feedback signaling determine susceptibility of breast cancer cells to MEK inhibition. (2009) (372)
The tumor microenvironment is a dominant force in multidrug resistance. (2012) (369)
Expression of extracellular matrix components is regulated by substratum (1990) (369)
Extracellular matrix signaling: integration of form and function in normal and malignant cells. (1998) (360)
Targeted expression of stromelysin-1 in mammary gland provides evidence for a role of proteinases in branching morphogenesis and the requirement for an intact basement membrane for tissue-specific gene expression [published erratum appears in J Cell Biol 1996 Feb;132(4):following 752] (1994) (354)
Suppression of apoptosis by basement membrane requires three-dimensional tissue organization and withdrawal from the cell cycle. (1996) (349)
Beta1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo. (2006) (341)
Fibrosis and cancer: Do myofibroblasts come also from epithelial cells via EMT? (2007) (340)
Tumor reversion: Correction of malignant behavior by microenvironmental cues (2003) (340)
Mammary gland development: cell fate specification, stem cells and the microenvironment (2015) (340)
Modeling dynamic reciprocity: engineering three-dimensional culture models of breast architecture, function, and neoplastic transformation. (2005) (329)
CSF1R inhibition delays cervical and mammary tumor growth in murine models by attenuating the turnover of tumor-associated macrophages and enhancing infiltration by CD8+ T cells (2013) (310)
Site-specific inductive and inhibitory activities of MMP-2 and MMP-3 orchestrate mammary gland branching morphogenesis (2003) (309)
HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment (2010) (306)
Unraveling the microenvironmental influences on the normal mammary gland and breast cancer. (2008) (298)
Modulation of secreted proteins of mouse mammary epithelial cells by the collagenous substrata (1984) (298)
Epithelial to mesenchymal transition in human breast cancer can provide a nonmalignant stroma. (2003) (292)
The need for complex 3D culture models to unravel novel pathways and identify accurate biomarkers in breast cancer. (2014) (292)
Tissue architecture and function: dynamic reciprocity via extra- and intra-cellular matrices (2009) (289)
Phenotypic reversion or death of cancer cells by altering signaling pathways in three-dimensional contexts. (2002) (289)
Microenvironmental regulators of tissue structure and function also regulate tumor induction and progression: the role of extracellular matrix and its degrading enzymes. (2005) (284)
Tissue structure, nuclear organization, and gene expression in normal and malignant breast. (1999) (284)
Interaction of mouse mammary epithelial cells with collagen substrata: regulation of casein gene expression and secretion. (1985) (282)
Myoepithelial Cells: Their Origin and Function in Breast Morphogenesis and Neoplasia (2005) (277)
Lumen formation by epithelial cell lines in response to collagen overlay: a morphogenetic model in culture. (1982) (276)
The matrix metalloproteinase stromelysin-1 acts as a natural mammary tumor promoter (2000) (274)
Targeting TACE-dependent EGFR ligand shedding in breast cancer. (2007) (265)
Extracellular matrix regulates expression of the TGF-beta 1 gene (1993) (260)
Mechanisms of Disease: epithelial–mesenchymal transition—does cellular plasticity fuel neoplastic progression? (2008) (255)
Tissue phenotype depends on reciprocal interactions between the extracellular matrix and the structural organization of the nucleus. (1998) (254)
Myoepithelial cells: good fences make good neighbors (2005) (250)
Evidence for formation of DNA repair centers and dose-response nonlinearity in human cells (2011) (246)
Epithelial-mesenchymal transition: general principles and pathological relevance with special emphasis on the role of matrix metalloproteinases. (2012) (244)
Polarity and proliferation are controlled by distinct signaling pathways downstream of PI3-kinase in breast epithelial tumor cells (2004) (243)
Rescue of mammary epithelial cell apoptosis and entactin degradation by a tissue inhibitor of metalloproteinases-1 transgene (1996) (243)
The Hyaluronan Receptors CD44 and Rhamm (CD168) Form Complexes with ERK1,2 That Sustain High Basal Motility in Breast Cancer Cells* (2007) (241)
Cellular growth and survival are mediated by beta 1 integrins in normal human breast epithelium but not in breast carcinoma. (1995) (236)
The differentiated state of normal and malignant cells or how to define a "normal" cell in culture. (1981) (230)
Extracellular matrix and hormones transcriptionally regulate bovine beta-casein 5' sequences in stably transfected mouse mammary cells. (1990) (225)
The importance of the microenvironment in breast cancer progression: recapitulation of mammary tumorigenesis using a unique human mammary epithelial cell model and a three-dimensional culture assay. (1996) (221)
Wounding and its role in RSV-mediated tumor formation. (1985) (218)
Human mammary luminal epithelial cells contain progenitors to myoepithelial cells. (1999) (217)
Mediation of wound-related Rous sarcoma virus tumorigenesis by TGF-beta. (1990) (214)
Prognostic Breast Cancer Signature Identified from 3D Culture Model Accurately Predicts Clinical Outcome across Independent Datasets (2008) (212)
Dynamic reciprocity: how do extracellular matrix and hormones direct gene expression? (1987) (204)
A novel transcriptional enhancer is involved in the prolactin- and extracellular matrix-dependent regulation of beta-casein gene expression. (1992) (201)
Beta1 integrin inhibition dramatically enhances radiotherapy efficacy in human breast cancer xenografts. (2008) (200)
Astrocytes regulate adult hippocampal neurogenesis through ephrin-B signaling (2012) (200)
Proteinases of the mammary gland: developmental regulation in vivo and vectorial secretion in culture. (1991) (196)
Inability of Rous sarcoma virus to cause sarcomas in the avian embryo (1984) (195)
Suppression of mammary epithelial cell differentiation by the helix-loop-helix protein Id-1 (1995) (195)
Involvement of extracellular matrix constituents in breast cancer. (1995) (192)
Mechanism of Akt1 inhibition of breast cancer cell invasion reveals a protumorigenic role for TSC2. (2006) (189)
Laminin and biomimetic extracellular elasticity enhance functional differentiation in mammary epithelia (2008) (186)
Human mammary progenitor cell fate decisions are products of interactions with combinatorial microenvironments. (2009) (184)
Tumors are unique organs defined by abnormal signaling and context. (2001) (183)
The MAPK(ERK-1,2) pathway integrates distinct and antagonistic signals from TGFalpha and FGF7 in morphogenesis of mouse mammary epithelium. (2007) (182)
From laminin to lamin: regulation of tissue-specific gene expression by the ECM. (1995) (181)
Breast cancer cells in three-dimensional culture display an enhanced radioresponse after coordinate targeting of integrin alpha5beta1 and fibronectin. (2010) (175)
The influence of tissue microenvironment (stroma and extracellular matrix) on the development and function of mammary epithelium. (1993) (172)
Ionizing radiation predisposes nonmalignant human mammary epithelial cells to undergo transforming growth factor beta induced epithelial to mesenchymal transition. (2007) (169)
MYC Suppresses Cancer Metastasis by Direct Transcriptional Silencing of αv and β3 Integrin Subunits (2012) (168)
A novel function for the nm23-H1 gene: overexpression in human breast carcinoma cells leads to the formation of basement membrane and growth arrest. (1994) (167)
A human breast cell model of preinvasive to invasive transition. (2008) (167)
Coherent angular motion in the establishment of multicellular architecture of glandular tissues (2012) (166)
Increased sugar uptake promotes oncogenesis via EPAC/RAP1 and O-GlcNAc pathways. (2014) (165)
Expression of autoactivated stromelysin-1 in mammary glands of transgenic mice leads to a reactive stroma during early development. (1998) (165)
Cell shape regulates global histone acetylation in human mammary epithelial cells. (2007) (164)
Three-dimensional culture of human breast epithelial cells: the how and the why. (2013) (163)
A Novel Pathway for Mammary Epithelial Cell Invasion Induced by the Helix-Loop-Helix Protein Id-1 (1998) (163)
Misregulation of Stromelysin-1 Expression in Mouse Mammary Tumor Cells Accompanies Acquisition of Stromelysin-1-dependent Invasive Properties* (1997) (160)
Extracellular matrix control of mammary gland morphogenesis and tumorigenesis: insights from imaging (2008) (159)
A role for dystroglycan in epithelial polarization: loss of function in breast tumor cells. (2002) (158)
β1 integrin mediates an alternative survival pathway in breast cancer cells resistant to lapatinib (2011) (154)
Rhamm−/− fibroblasts are defective in CD44-mediated ERK1,2 motogenic signaling, leading to defective skin wound repair (2006) (154)
Epimorphin Functions as a Key Morphoregulator for Mammary Epithelial Cells (1998) (151)
Rac 1 b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability (2009) (150)
The development of a functionally relevant cell culture model of progressive human breast cancer. (1995) (148)
The Organization of Tight Junctions in Epithelia: Implications for Mammary Gland Biology and Breast Tumorigenesis (2003) (146)
The tumor microenvironment modulates tamoxifen resistance in breast cancer: a role for soluble stromal factors and fibronectin through β1 integrin (2012) (145)
Tissue architecture: the ultimate regulator of epithelial function? (1998) (144)
Tissue architecture and breast cancer: the role of extracellular matrix and steroid hormones. (2000) (139)
The dominance of the microenvironment in breast and ovarian cancer. (2002) (135)
Gene expression signature in organized and growth-arrested mammary acini predicts good outcome in breast cancer. (2006) (134)
A novel regulatory mechanism for whey acidic protein gene expression. (1989) (134)
Inflammation is responsible for the development of wound-induced tumors in chickens infected with Rous sarcoma virus. (1994) (131)
Patterned Collagen Fibers Orient Branching Mammary Epithelium through Distinct Signaling Modules (2013) (129)
Targeting the tumor microenvironment. (2007) (129)
Cytodifferentiation of mouse mammary epithelial cells cultured on a reconstituted basement membrane reveals striking similarities to development in vivo. (1991) (129)
Change in cell shape is required for matrix metalloproteinase‐induced epithelial‐mesenchymal transition of mammary epithelial cells (2008) (127)
Dynamic reciprocity revisited: a continuous, bidirectional flow of information between cells and the extracellular matrix regulates mammary epithelial cell function. (1995) (124)
Designer microenvironments for the analysis of cell and tissue function. (1990) (123)
Three-dimensional lithographically defined organotypic tissue arrays for quantitative analysis of morphogenesis and neoplastic progression (2008) (123)
The plasticity of human breast carcinoma cells is more than epithelial to mesenchymal conversion (2001) (123)
The Significance of Matrix Metalloproteinases during Early Stages of Tumor Progression a (1998) (120)
Sustained activation of STAT5 is essential for chromatin remodeling and maintenance of mammary-specific function (2009) (118)
Division of Labor among the α6β4 Integrin, β1 Integrins, and an E3 Laminin Receptor to Signal Morphogenesis and β-Casein Expression in Mammary Epithelial Cells (1999) (118)
Is CD133 a marker of metastatic colon cancer stem cells? (2008) (117)
Characterization of BCE-1, a Transcriptional Enhancer Regulated by Prolactin and Extracellular Matrix and Modulated by the State of Histone Acetylation (1998) (115)
The extracellular matrix in epithelial biology: shared molecules and common themes in distant phyla. (1996) (113)
The tumor-promoting effect of wounding: a possible role for TGF-beta-induced stromal alterations. (1994) (112)
Proteolytic Enzymes and Altered Glycosylation Modulate Dystroglycan Function in Carcinoma Cells (2004) (111)
FAM83A confers EGFR-TKI resistance in breast cancer cells and in mice. (2012) (111)
Order and Disorder: The Role of Extracellular Matrix in Epithelial Cancer (2002) (111)
Breast cancer by proxy: can the microenvironment be both the cause and consequence? (2009) (110)
Disruption of 3D tissue integrity facilitates adenovirus infection by deregulating the coxsackievirus and adenovirus receptor (2003) (108)
Splicing program of human MENA produces a previously undescribed isoform associated with invasive, mesenchymal-like breast tumors (2012) (107)
Tumor plasticity allows vasculogenic mimicry, a novel form of angiogenic switch. A rose by any other name? (1999) (107)
Rap1 integrates tissue polarity, lumen formation, and tumorigenic potential in human breast epithelial cells. (2007) (106)
Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity (2012) (104)
Extracellular Matrix-regulated Gene Expression Requires Cooperation of SWI/SNF and Transcription Factors* (2006) (103)
Mammary gland tumor formation in transgenic mice overexpressing stromelysin-1. (1995) (102)
Dystroglycan loss disrupts polarity and β-casein induction in mammary epithelial cells by perturbing laminin anchoring (2006) (101)
Extracellular matrix remodeling and the regulation of epithelial-stromal interactions during differentiation and involution. (1996) (99)
Reproducibility: The risks of the replication drive (2013) (99)
Depletion of nuclear actin is a key mediator of quiescence in epithelial cells (2011) (98)
Raf-induced MMP9 disrupts tissue architecture of human breast cells in three-dimensional culture and is necessary for tumor growth in vivo. (2010) (97)
To create the correct microenvironment: three-dimensional heterotypic collagen assays for human breast epithelial morphogenesis and neoplasia. (2003) (97)
Extracellular matrix signaling from the cellular membrane skeleton to the nuclear skeleton: a model of gene regulation. (1996) (97)
Self-organization of engineered epithelial tubules by differential cellular motility (2009) (97)
alpha1 and alpha2 integrins mediate invasive activity of mouse mammary carcinoma cells through regulation of stromelysin-1 expression. (1999) (96)
IL-25 Causes Apoptosis of IL-25R–Expressing Breast Cancer Cells Without Toxicity to Nonmalignant Cells (2011) (96)
Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin β1 (2013) (96)
Collagen-IV and laminin-1 regulate estrogen receptor α expression and function in mouse mammary epithelial cells (2003) (95)
The embryonic environment strongly attenuates v-src oncogenesis in mesenchymal and epithelial tissues, but not in endothelia (1990) (95)
Single proteins might have dual but related functions in intracellular and extracellular microenvironments (2009) (94)
Dependence of the differentiated state on the cellular environment: modulation of collagen synthesis in tendon cells. (1977) (92)
Extracellular matrix regulates whey acidic protein gene expression by suppression of TGF-alpha in mouse mammary epithelial cells: studies in culture and in transgenic mice (1995) (91)
Cytoplasmic SnoN in normal tissues and nonmalignant cells antagonizes TGF-beta signaling by sequestration of the Smad proteins. (2005) (90)
Respect Thy Neighbor! (2004) (90)
Tumor engineering: the other face of tissue engineering. (2010) (88)
Three-dimensional cultures of mouse mammary epithelial cells. (2013) (88)
An odyssey from breast to bone: Multi‐step control of mammary metastases and osteolysis by matrix metalloproteinases (1999) (87)
Dissecting regional variations in stress fiber mechanics in living cells with laser nanosurgery. (2010) (87)
AZU-1: a candidate breast tumor suppressor and biomarker for tumor progression. (2000) (87)
FAM83 family oncogenes are broadly involved in human cancers: an integrative multi‐omics approach (2017) (86)
Molecular Predictors of 3D Morphogenesis by Breast Cancer Cell Lines in 3D Culture (2010) (86)
The hemopexin domain of MMP3 is responsible for mammary epithelial invasion and morphogenesis through extracellular interaction with HSP90β. (2013) (85)
Ionizing radiation induces heritable disruption of epithelial cell interactions (2003) (84)
Development of avian sarcoma and leukosis virus-based vector-packaging cell lines (1988) (84)
Modeling Host-Pathogen Interactions in the Context of the Microenvironment: Three-Dimensional Cell Culture Comes of Age (2018) (84)
Putting Tumors in Context (2010) (83)
Polo-like kinase 1 is involved in invasion through extracellular matrix. (2007) (83)
Collagenous substrata regulate the nature and distribution of glycosaminoglycans produced by differentiated cultures of mouse mammary epithelial cells. (1985) (82)
Localization of plasma membrane and secretory calcium pumps in the mammary gland. (2008) (81)
Functional Culture Models to Study Mechanisms Governing Apoptosis in Normal and Malignant Mammary Epithelial Cells (1999) (81)
Regulation of gene expression and cell function by extracellular matrix. (1993) (80)
Reversible Aptamer-Au Plasmon Rulers for Secreted Single Molecules. (2015) (80)
Sorting out the FACS: a devil in the details. (2014) (80)
Structural Cues from the Tissue Microenvironment Are Essential Determinants of the Human Mammary Epithelial Cell Phenotype (1998) (78)
High-level expression of the rat whey acidic protein gene is mediated by elements in the promoter and 3' untranslated region (1992) (77)
Differentiation and cancer in the mammary gland: shedding light on an old dichotomy. (1998) (76)
Tenascin-C inhibits extracellular matrix-dependent gene expression in mammary epithelial cells. Localization of active regions using recombinant tenascin fragments. (1995) (75)
Synergism between anti-microtubule agents and growth stimulants in enhancement of cell cycle traverse (1977) (75)
Interaction of E-cadherin and PTEN regulates morphogenesis and growth arrest in human mammary epithelial cells. (2009) (75)
Delivering the message: epimorphin and mammary epithelial morphogenesis. (2003) (74)
Constructing Three-Dimensional Models to Study Mammary Gland Branching Morphogenesis and Functional Differentiation (2012) (74)
Extracellular matrix, nuclear and chromatin structure, and gene expression in normal tissues and malignant tumors: a work in progress. (2006) (72)
Cell differentiation by extracellular matrix components. (1994) (71)
Epimorphin Mediates Mammary Luminal Morphogenesis through Control of C/EBPβ (2001) (70)
Of plasticity and specificity: dialectics of the microenvironment and macroenvironment and the organ phenotype (2014) (69)
Targeted Expression of Stromelysin-1 in Mammary Gland Provides Evidence for a Role of Proteinases in Branching Morphogenesis and the Requirement for an Intact BasementMembrane for Tissue-specific Gene Expression (2002) (69)
Glucose metabolism by adult hepatocytes in primary culture and by cell lines from rat liver. (1978) (69)
Interaction of tumour promoters with epithelial cells in culture. An immunofluorescence study. (1985) (68)
Origination of Organismal Form : Beyond the Gene in Developmental and Evolutionary Biology (2014) (68)
Evaluation of normalization methods for cDNA microarray data by k-NN classification (2005) (68)
Nidogen-1 regulates laminin-1-dependent mammary-specific gene expression. (2000) (67)
Collective epithelial cell invasion overcomes mechanical barriers of collagenous extracellular matrix by a narrow tube-like geometry and MMP14-dependent local softening. (2011) (67)
Of Microenvironments and Mammary Stem Cells (2007) (66)
Mammary Epithelial-Mesenchymal Interaction Regulates Fibronectin Alternative Splicing via Phosphatidylinositol 3-Kinase* (2004) (66)
Regulation of functional cytodifferentiation and histogenesis in mammary epithelial cells: role of the extracellular matrix. (1989) (65)
MCF-10A-NeoST: a new cell system for studying cell-ECM and cell-cell interactions in breast cancer. (2001) (65)
Transferrin mRNA level in the mouse mammary gland is regulated by pregnancy and extracellular matrix. (1987) (65)
Apical polarity in three-dimensional culture systems: where to now? (2010) (62)
Expression of Hoxa‐1 and Hoxb‐7 is regulated by extracellular matrix‐dependent signals in mammary epithelial cells (1998) (62)
Epithelial progenitor cell lines as models of normal breast morphogenesis and neoplasia (2003) (62)
Extracellular Matrix Regulates Expression of the TGF-/31 Gene (1993) (62)
Patterns of glucose metabolism in normal and virus-transformed chick cells in tissue culture. (1972) (62)
Deep nuclear invaginations are linked to cytoskeletal filaments – integrated bioimaging of epithelial cells in 3D culture (2017) (62)
Simultaneous classification and relevant feature identification in high-dimensional spaces: application to molecular profiling data (2003) (62)
Polarity determination in breast tissue: desmosomal adhesion, myoepithelial cells, and laminin 1 (2003) (61)
Self-organization is a dynamic and lineage-intrinsic property of mammary epithelial cells (2011) (60)
Gene Expression in the Third Dimension: The ECM-nucleus Connection (2010) (60)
Casein gene expression in mouse mammary epithelial cell lines: dependence upon extracellular matrix and cell type. (1987) (59)
A respiration-deficient Chinese hamster cell line with a defect in NADH-coenzyme Q reductase. (1976) (58)
Higher-order nuclear organization in growth arrest of human mammary epithelial cells: a novel role for telomere-associated protein TIN2 (2004) (56)
Cellular heterogeneity profiling by hyaluronan probes reveals an invasive but slow-growing breast tumor subset (2014) (56)
Matrix metalloproteinase-induced genomic instability. (2006) (56)
Automated local bright feature image analysis of nuclear protein distribution identifies changes in tissue phenotype. (2006) (55)
Cell shape and hexose transport in normal and virus-transformed cells in culture. (2010) (55)
Ascorbic acid inhibits replication and infectivity of avian RNA tumor virus. (1980) (54)
Evaluation of the cocarcinogenic effect of wounding in Rous sarcoma virus tumorigenesis. (1989) (54)
14-3-3σ stabilizes a complex of soluble actin and intermediate filament to enable breast tumor invasion (2013) (53)
Laminin-111 and the Level of Nuclear Actin Regulate Epithelial Quiescence via Exportin-6. (2017) (53)
Cancer. Respect thy neighbor! (2004) (53)
β1 and β4 integrins: from breast development to clinical practice (2014) (53)
Chromatin organization measured by AluI restriction enzyme changes with malignancy and is regulated by the extracellular matrix and the cytoskeleton. (2005) (51)
Studies of Muc-1 mucin expression and polarity in the mouse mammary gland demonstrate developmental regulation of Muc-1 glycosylation and establish the hormonal basis for mRNA expression. (1992) (50)
Inhibition of vimentin or β1 integrin reverts morphology of prostate tumor cells grown in laminin-rich extracellular matrix gels and reduces tumor growth in vivo (2009) (50)
Division of labor among the alpha6beta4 integrin, beta1 integrins, and an E3 laminin receptor to signal morphogenesis and beta-casein expression in mammary epithelial cells. (2011) (49)
Modelling molecular mechanisms of breast cancer and invasion: lessons from the normal gland. (2007) (49)
Cell-ECM interactions in development (1995) (48)
Endothelial cell migration and vascular endothelial growth factor expression are the result of loss of breast tissue polarity. (2009) (47)
Form and Function in the Mammary Gland (1987) (47)
Nuclear repartitioning of galectin-1 by an extracellular glycan switch regulates mammary morphogenesis (2016) (46)
Epimorphin overexpression in the mouse mammary gland promotes alveolar hyperplasia and mammary adenocarcinoma. (2005) (46)
Localization of 9E3/CEF-4 in avian tissues: expression is absent in Rous sarcoma virus-induced tumors but is stimulated by injury (1990) (45)
Mammary epithelial cells, extracellular matrix, and gene expression. (1991) (45)
The use of fluorescamine as a probe for labeling the outer surface of the plasma membrane. (1976) (45)
Dynamics of metabolism of normal and virus-transformed chick cells in culture. (1973) (45)
NFkB disrupts tissue polarity in 3D by preventing integration of microenvironmental signals (2013) (44)
Lawrence Berkeley National Laboratory Lawrence Berkeley National Laboratory (2007) (44)
Glucose metabolite patterns as markers of functional differentiation in freshly isolated and cultured mouse mammary epithelial cells. (1981) (43)
Photonic gene circuits by optically addressable siRNA-Au nanoantennas. (2012) (43)
p53-dependent integration of telomere and growth factor deprivation signals (2007) (43)
Quantitative immunocytochemical assay for infectious avian retroviruses. (1987) (42)
E7-transduced human breast epithelial cells show partial differentiation in three-dimensional culture. (1999) (42)
Laminin regulates PI3K basal localization and activation to sustain STAT5 activation (2010) (41)
Inhibitors of Rho kinase (ROCK) signaling revert the malignant phenotype of breast cancer cells in 3D context (2016) (41)
Regulation of milk protein and basement membrane gene expression: the influence of the extracellular matrix. (1988) (41)
Goodbye flat biology – time for the 3rd and the 4th dimensions (2017) (41)
Is the product of the src gene a promoter? (1979) (40)
Leucine in cultured cells: its metabolism and use as a marker for protein turnover. (1977) (40)
Interconnected contribution of tissue morphogenesis and the nuclear protein NuMA to the DNA damage response (2012) (39)
Ascorbate induction of collagen synthesis as a means for elucidating a mechanism of quantitative control of tissue-specific function. (1981) (39)
A device for maintaining viable cells at high densities for NMR studies (1983) (38)
Insulin effect on the cell cycle: analysis of the kinetics of growth parameters in confluent chick cells. (1976) (37)
Primary avian tendon cells in culture. An improved system for understanding malignant transformation (1978) (35)
Homeostasis in the breast: it takes a village. (2004) (35)
TPA induces simultaneous alterations in the synthesis and organization of vimentin. (1983) (33)
Homology with Vesicle Fusion Mediator Syntaxin-1a Predicts Determinants of Epimorphin/Syntaxin-2 Function in Mammary Epithelial Morphogenesis* (2009) (33)
Tumor promoters alter gene expression and protein phosphorylation in avian cells in culture. (1981) (33)
Epigenetic reversion of breast carcinoma phenotype is accompanied by changes in DNA sequestration as measured by AluI restriction enzyme. (2007) (33)
Communication between the cell membrane and the nucleus: Role of protein compartmentalization (1998) (33)
The metastasis-promoting protein S100A4 regulates mammary branching morphogenesis. (2011) (32)
Metastasis: Pathways of parallel progression (2016) (31)
Selective inhibition of the facilitated mode of sugar uptake by cytochalasin B in cultured chick fibroblasts. (1975) (31)
Perturbed myoepithelial cell differentiation in BRCA mutation carriers and in ductal carcinoma in situ (2019) (31)
Biomechanical Approaches for Studying Integration of Tissue Structure and Function in Mammary Epithelia (2004) (30)
Transient external force induces phenotypic reversion of malignant epithelial structures via nitric oxide signaling (2018) (29)
Laminin signals initiate the reciprocal loop that informs breast-specific gene expression and homeostasis by activating NO, p53 and microRNAs (2017) (29)
An “elite hacker” (2012) (29)
α1 and α2 Integrins Mediate Invasive Activity of Mouse Mammary Carcinoma Cells through Regulation of Stromelysin-1 Expression (1999) (29)
Leucine in cultured cells. [/sup 14/C tracer technique] (1977) (29)
Asymmetric expression of connexins between luminal epithelial- and myoepithelial- cells is essential for contractile function of the mammary gland. (2015) (28)
Expression of Rous sarcoma virus-derived retroviral vectors in the avian blastoderm: potential as stable genetic markers. (1991) (28)
Transport as a rate limiting step in glucose metabolism in virus‐transformed cells: Studies with cytochalasin B (1976) (28)
Breast Cancer Cells in Three-dimensional Culture Display an Enhanced Radioresponse after Coordinate Targeting of Integrin ?5?1 and Fibronectin (2010) (28)
Astrocytic laminin-211 drives disseminated breast tumor cell dormancy in brain (2021) (27)
The tyrosine phosphorylation substrate p36 is developmentally regulated in embryonic avian limb and is induced in cell culture (1986) (27)
Mechanism of Excretion of a Bacterial Proteinase: Factors Controlling Accumulation of the Extracellular Proteinase of a Sarcina Strain (Coccus P) (1971) (27)
Malignant Mammary Cells Acquire Independence from Extracellular Context for Regulation of Estrogen Receptor α (2004) (27)
Deficiency of the p53/p63 target Perp alters mammary gland homeostasis and promotes cancer (2012) (27)
Receptor for hyaluronan mediated motility (RHAMM/HMMR) is a novel target for promoting subcutaneous adipogenesis. (2017) (26)
NF-kappaB links oestrogen receptor signalling and EMT. (2007) (26)
Metabolic cooperativity between epithelial cells and adipocytes of mice. (1981) (26)
SnoN regulates mammary gland alveologenesis and onset of lactation by promoting prolactin/Stat5 signaling (2012) (26)
Interrelationship of glycogen metabolism and lactose synthesis in mammary epithelial cells of mice. (1980) (26)
Training the next generation of biomedical investigators in glycosciences. (2016) (26)
Leakage as the source of overgrowth stimulating activity in Rous sarcoma transformed cultures. (1971) (24)
The Ecology of Tumors: By perturbing the microenvironment, wounds and infection may be key to tumor development. (2006) (24)
Fibronectin rescues estrogen receptor α from lysosomal degradation in breast cancer cells (2018) (23)
SnapShot: Branching Morphogenesis (2014) (23)
Proliferation and Polarity in Breast Cancer: Untying the Gordian Knot (2005) (23)
Modelling breast cancer requires identification and correction of a critical cell lineage-dependent transduction bias (2015) (23)
Preferential inhibition of the growth of virus-transformed cells in culture by rifazone-82, a new rifamycin derivative. (1974) (23)
Subcellular Localization and Ser-137 Phosphorylation Regulate Tumor-suppressive Activity of Profilin-1* (2015) (23)
Plasma membrane reorganization induced by tumor promoters in an epithelial cell line. (2011) (23)
ATM Suppresses SATB1-Induced Malignant Progression in Breast Epithelial Cells (2012) (23)
Gene expression and regulation : the legacy of Luigi Gorini (1988) (22)
NF-κB links oestrogen receptor signalling and EMT (2007) (22)
Cell-to-cell contact and extracellular matrix: Integration of form and function: the central role of adhesion molecules (1999) (22)
Quantitative tracer studies of metabolic dynamics of animal cells growing in tissue culture. (1974) (21)
Integrins, Signaling, and the Remodeling of the Extracellular Matrix (1994) (21)
In vivo and in vitro expression of human serum albumin genomic sequences in mammary epithelial cells with β‐lactoglobulin and whey acidic protein promoters (1999) (21)
The 9E3 protein: immunolocalization in vivo and evidence for multiple forms in culture. (1992) (21)
Glycerol phosphate shuttle in virus-transformed cells in culture. (1976) (21)
Identification of genetic loci that control mammary tumor susceptibility through the host microenvironment (2015) (20)
An interferon signature identified by RNA-sequencing of mammary tissues varies across the estrous cycle and is predictive of metastasis-free survival (2014) (20)
Laser scanning-based tissue autofluorescence/fluorescence imaging (LS-TAFI), a new technique for analysis of microanatomy in whole-mount tissues. (2012) (20)
The role of metalloproteinases and their inhibitors in regulating mammary epithelial morphology and function in vivo (1995) (20)
New insight into the role of MMP14 in metabolic balance (2016) (20)
Cell nucleus in context. (2000) (20)
Transcriptlonal activation by viral enhancers: Critical dependence on extracellular matrix‐cell interactions in mammary epithelial cells (1994) (19)
Quis custodiet ipsos custodies: who watches the watchmen? (2009) (19)
Wound-factor-induced and cell cycle phase-dependent expression of 9E3/CEF4, the avian gro gene. (1991) (19)
Architecture Is the Message: The role of extracellular matrix and 3-D structure in tissue-specific gene expression and breast cancer. (2007) (18)
Role of src gene in growth regulation of Rous sarcoma virus-infected chicken embryo fibroblasts (1980) (18)
Transcriptional regulation of stromelysin-1 gene expression is altered during progression of mouse mammary epithelial cells from functionally normal to malignant. (1999) (18)
Mammary Branching Morphogenesis Requires Reciprocal Signaling by Heparanase and MMP‐14 (2015) (18)
Estrogen and progesterone receptors have distinct roles in the establishment of the hyperplastic phenotype in PR-A transgenic mice (2009) (18)
Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin β1 (2013) (17)
The pattern of hMENA isoforms is regulated by TGF-β1 in pancreatic cancer and may predict patient outcome (2016) (17)
Depletion of nuclear actin is a key mediator of quiescence in epithelial cells (2011) (17)
Sustained activation of STAT 5 is essential for chromatin remodeling and maintenance of mammary-specifi c function (2009) (16)
Cultures of Mammary Epithelial Cells: Extracellular Matrix and Functional Differentiation (1988) (16)
Mechanism of Akt 1 inhibition of breast cancer cell invasion reveals a protumorigenic role for TSC 2 (2006) (16)
The Role of Tumor Microenvironment and Exosomes in Dormancy and Relapse. (2021) (16)
Characterization of the intermediate filament proteins of murine mammary gland epithelial cells. Response to collagen substratum. (1986) (16)
Systems-Level Properties of EGFR-RAS-ERK Signaling Amplify Local Signals to Generate Dynamic Gene Expression Heterogeneity. (2020) (16)
Cancer stem cells in breast and prostate: Fact or fiction? (2019) (15)
Reprogramming stem cells is a microenvironmental task (2008) (15)
Control of expression of an integrated Rous sarcoma provirus in rat cells: role of 5' genomic duplications reveals unexpected patterns of gene transcription and its regulation (1986) (15)
Pathways Involved in Formation of Mammary Organoid Architecture Have Keys to Understanding Drug Resistance and to Discovery of Druggable Targets. (2016) (15)
Trichostatin a inhibits β‐casein expression in mammary epithelial cells (2001) (15)
Glandular Structure and Gene Expression: Lessons from the Mammary Gland a (1998) (15)
Fructose utilization and altered cytochrome P-450 in cultured hepatocytes from adult rats. (1980) (15)
FAM 83 A confers EGFR-TKI resistance in breast cancer cells and in mice (2012) (15)
Transferrin is a major mouse milk protein and is synthesized by mammary epithelial cells (1987) (14)
Uncovering the dual role of RHAMM as an HA receptor and a regulator of CD44 expression in RHAMM-expressing mesenchymal progenitor cells (2015) (14)
Imaging of homeostatic, neoplastic, and injured tissues by HA-based probes. (2012) (14)
Conversion of glucose to sorbitol and fructose by liver-derived cells in culture. (1978) (14)
Inhibition of infectious Rous sarcoma virus production by rifamycin derivative (1976) (14)
The Microenvironment of the Breast: Three‐Dimensional Models to Study the Roles of the Stroma and the Extracellular Matrix in Function and Dysfunction (1995) (14)
Control of Mammary Epithelial Differentiation: The Separate Roles of Cell-substratum and cell-cell interaction (1991) (14)
Characterization of a photoproduct of 7,12-dimethylbenz[alpha]anthracene and its effects on chick-embryo cells in culture. (1977) (13)
MODULATION OF THE DIFFERENTIATED PHENOTYPE OF CULTURED MOUSE MAMMARY EPITHELIAL CELLS BY COLLAGEN SUBSTRATA (1982) (13)
Tissue tropism and temporal expression of Rous sarcoma virus in embryonic avian limb in ovo. (1987) (13)
hMENA isoforms impact NSCLC patient outcome through fibronectin/β1 integrin axis (2018) (13)
Expression of integrated Rous sarcoma viruses: DNA rearrangements 5′ to the provirus are common in transformed rat cells but not seen in infected but untransformed cells. (1986) (13)
Transcriptional activation by viral enhancers: critical dependence on extracellular matrix-cell interactions in mammary epithelial cells. (1994) (13)
Controlled microaspiration for high‐pressure freezing: a new method for ultrastructural preservation of fragile and sparse tissues for TEM and electron tomography (2008) (13)
Ensemble attribute profile clustering: discovering and characterizing groups of genes with similar patterns of biological features (2006) (12)
Raf-induced MMP 9 disrupts tissue architecture of human breast cells in three-dimensional culture and is necessary for tumor growth in vivo (2010) (12)
Three Dimensional Cell Culture: The Importance of Microenvironment in Regulation of Function (2006) (12)
Network Analysis of Breast Cancer Progression and Reversal Using a Tree-Evolving Network Algorithm (2014) (12)
The uncoupled regulation of fibronectin and collagen synthesis in Rous sarcoma virus transformed avian tendon cells. (1979) (12)
Prostate cancer in bone: importance of context for inhibition of matrix metalloproteinases. (2002) (12)
B 1 Integrin Inhibition Dramatically Enhances Radiotherapy Efficacy in Human Breast Cancer Xenografts comparable growth inhibition and apoptosis in breast cancer xenografts in vivo (11)
pp60v-src tyrosine kinase is expressed and active in sarcoma-free avian embryos microinjected with Rous sarcoma virus. (1988) (11)
Rap 1 Integrates Tissue Polarity , Lumen Formation , and Tumorigenic Potential in Human Breast Epithelial Cells (2006) (11)
Regulation of mammary epithelial cell function: a role for stromal and basement membrane matrices (1990) (11)
Side effects of amphotericin B-deoxycholate (fungizone) and nystatin in chick cells in culture (2007) (11)
3D culture models of normal and malignant breast epithelial cells (2006) (11)
Ion-retardation desalting of blood and other animal tissues for separation of soluble metabolites by two-dimensional chromatography. (1977) (11)
184AA3: a xenograft model of ER+ breast adenocarcinoma (2015) (11)
The PI3K/mTOR inhibitor Gedatolisib eliminates dormant breast cancer cells in organotypic culture, but fails to prevent metastasis in preclinical settings (2021) (11)
One-shot computation of reachable sets for differential games (2013) (11)
integrin inhibition dramatically enhances radiotherapy efficacy in human breast cancer xenografts (2008) (10)
The hemopexin domain of MMP 3 is responsible for mammary epithelial invasion and morphogenesis through extracellular interaction with HSP 90 b (2013) (10)
Introduction: The Role of Myoepithelial Cells in Integration of Form and Function in the Mammary Gland (2005) (10)
Proceedings of the Third International Conference on Recent Advances and Future Directions in Endocrine Manipulation of Breast Cancer (2004) (10)
Thinking in three dimensions: discovering reciprocal signaling between the extracellular matrix and nucleus and the wisdom of microenvironment and tissue architecture (2016) (10)
Of plasticity and specificity: dialectics of the micro- and macro-environment and the organ phenotype. (2014) (10)
Modeling mammary gland morphogenesis as a reaction-diffusion process (2004) (10)
A simple technique for detection and quantitation of lactose synthesis and secretion. (1979) (9)
V-K-ras transformation induces reversion to an earlier developmental form in adult rat adrenal cells. (1990) (9)
Iron Supplementation Eliminates Antagonistic Interactions Between Root-Associated Bacteria (2020) (9)
The consequences of bisulfite exposure in primary chick embryo fibroblast in culture (1977) (8)
Functional interplay between extracellular matrix and extracellular matrix-degrading proteinases in the mammary gland: a coordinate system for regulating mammary epithelial function (1992) (8)
Requirements for maintaining the embryonic state of avian tendon cells in culture (2007) (8)
Caveolin-1: Would-be Achilles’ heel of tumor microenvironment? (2011) (8)
The Central Role of Basement Membrane in Functional Differentiation, Apoptosis, and Cancer (1997) (8)
Toward plasmonics-enabled spatiotemporal activity patterns in three-dimensional culture models (2013) (8)
Mechanism of Excretion of a Bacterial Proteinase: Demonstration of Two Proteolytic Enzymes Produced by a Sarcina Strain (Coccus P) (1971) (7)
MCF-10 A-NeoST : A New Cell System for Studying Cell-ECM and Cell-Cell Interactions in Breast Cancer 1 (2001) (7)
Regulation of gene expression by extracellular matrix (1995) (7)
EXTRACELLULAR MATRIX AND MORPHOGENESIS: COLLAGEN OVERLAY INDUCES LUMEN FORMATION BY EPITHELIAL CELL LINES (1982) (7)
Suppression of ICE and apoptosis in mammary epithelial cells by the extracellular matrix and the cytoskeleton (1995) (7)
A Functionally Robust Phenotypic Screen that Identifies Drug Resistance-associated Genes Using 3D Cell Culture. (2018) (6)
The mammary gland as an experimental model : a subject collection from Cold Spring Harbor perspectives in biology (2011) (6)
Q&A: Mina Bissell on tumors as organs. (2013) (6)
The Ecology of Tumors (2006) (6)
Top-Down Analysis of a Dynamic Environment: Extracellular Matrix Structure and Function (2008) (6)
Molecular Predictors of 3 D Morphogenesis by Breast Cancer Cell Lines in 3 D Culture (2010) (6)
Epimorphin is a novel regulator of the progesterone receptor isoform-a. (2013) (5)
Alterations in Progesterone Receptor Isoform Balance in Normal and Neoplastic Breast Cells Modulates the Stem Cell Population (2020) (5)
Extracellular localization of epimorphin/syntaxin-2. (2007) (5)
Rethinking Cancer A New Paradigm for the Postgenomics Era (2020) (5)
The Extracellular Matrix as a Multivalent Signaling Scaffold that Orchestrates Tissue Organization and Function (2011) (5)
The Significance of the Extracellular Matrix in Mammary Epithelial Carcinogenesis (1993) (5)
EXTRACELLULAR MATRIX DEPENDENT GENE REGULATION IN MAMMARY EPITHELIAL CELLS (1995) (5)
TACE-dependent EGFR ligand shedding: A new target in basal breast cancer (2007) (4)
A Role for the Extracellular Matrix in Autocrine and Paracrine Regulation of Tissue-Specific Functions (1989) (4)
The Extracellular Matrix (1990) (4)
Substratum affects production and distribution of glycosamino glycans from epithelial cell lines (1982) (4)
Mammary Gland Development (1995) (4)
Extracellular Matrix and Nuclear Matrix Interactions May Regulate Apoptosis and Tissue-Specific Gene Expression: A Concept Whose Time has Come (1997) (4)
Testing for tumor promoters inEuphorbia lathyris: Analysis of possible health hazards (1981) (4)
16 – The Role of the Microenvironment in Tumor Initiation, Progression, and Metastasis (2015) (3)
Antiviral Action of a Rifamycin Derivative: Formation of Rous Sarcoma Virus Particles Deficient in 60 to 70S RNA (1978) (3)
The microstructure of laminin-111 compensates for dystroglycan loss in mammary epithelial cells in downstream expression of milk proteins. (2019) (3)
Advances in Brief E 7-transduced Human Breast Epithelial Cells Show Partial Differentiation in Three-dimensional Culture 1 (1999) (3)
Goodbye flat biology – time for the 3rd and the 4th dimensions (2017) (3)
Mina J. Bissell: Context Matters. (2015) (3)
Metabolism in normal and virus-transformed chick embryo fibroblasts as observed with glucose labeled with 14C and tritium and with tritium-labeled water. (1975) (3)
Extracellular localization of epimorphin/syntaxin-2. Authors' reply (2007) (3)
Inhibition of adenocarcinoma TA3 ascites tumor growth by rifamycin derivatives. (1978) (3)
Extracellular matrix: Tissue-specific regulator of cell proliferation (2004) (3)
Extracellular Matrix Remodeling in Mammary Gland Branching Morphogenesis and Breast Cancer (2005) (3)
Regulation of Tissue-Specific Gene Expression in the Mammary Gland: The Role of the Extracellular Matrix (1988) (3)
From Microenvironment to Nanoenvironment: Ultrastructure and Function of Extracellular Matrix (2014) (3)
Expression of Hoxa‐1 and Hoxb‐7 is regulated by extracellular matrix‐dependent signals in mammary epithelial cells. J Cell Biochem 69:377–391. (1998) (3)
Culture systems for studying malignancy (1979) (3)
Introduction: Form and Function in the Epithelia (1993) (3)
From single cells to biology. (2012) (2)
Lawrence Berkeley National Laboratory Recent Work Title Inhibitors of Rho kinase ( ROCK ) signaling revert the malignant phenotype of breast cancer cells in 3 D context Permalink (2016) (2)
p-Nitrophenyl-β-d-xyloside modulates proteoglycan synthesis and secretory differentiation in mouse mammary epithelial cell cultures (1988) (2)
Basal-subtype and MEK-PI3K feedback signaling determine susceptibility of breast cancer cells to MEK inhibition (2008) (2)
Introduction: basic science aspects of breast cancer. (1995) (2)
Lawrence Berkeley National Laboratory Recent Work Title Deep nuclear invaginations are linked to cytoskeletal filaments-integrated bioimaging of epithelial cells in 3 D culture Permalink (2016) (2)
Ionizing radiation predisposes non-malignant human mammary epithelial cells to undergo TGF beta-induced epithelial to mesenchymal transition (2007) (2)
Ascorbate induction of collagen synthesis as a means for elucidating a mechanism of quantitative control of tissue-specific function (1981) (2)
Mammary gland as a model for studies of gene expression in normal and malignant cells. (1990) (2)
The not-so-sweet side of sugar: Influence of the microenvironment on the processes that unleash cancer. (2020) (2)
Extracellular Matrix: The Networking Solution (2005) (2)
Inhibition of vimentin or B 1 integrin reverts morphology of prostate tumor cells grown in laminin-rich extracellular matrix gels and reduces tumor growth in vivo (2009) (2)
Rhizobacteria Mediate the Phytotoxicity of a Range of Biorefinery‐Relevant Compounds (2019) (2)
Culturing Mammary Stem Cells (2007) (2)
GROWTH REGULATION IN RSV INFECTED CHECKEN EMBRYO FIBROBLASTS: THE ROLE OF THE src GENE (1980) (2)
β1 and β4 integrins: from breast development to clinical practice (2014) (2)
Three-Dimensional Cultures of Normal and Malignant Human Breast Epithelial Cells to Achieve in vivo-like Architecture and Function (2005) (1)
An engineered tissue model to determine position-specific behavior during mammary epithelial branching morphogenesis (2006) (1)
Modeling Host-Pathogen Interactions in the Context of the Microenvironment: 3-D Cell Culture Comes of Age (2018) (1)
Δ133p53 coordinates ECM-driven morphogenesis and gene expression in 3-dimensional mammary epithelial acini. (2022) (1)
Integrative biology editorial 2010. One year and beyond: the excitement continues. (2010) (1)
Deep nuclear invaginations linked to cytoskeletal filaments: Integrated Bioimaging of epithelial cells in 3D culture - Supplemental Movies (2016) (1)
β1 Integrin Inhibition Enhances Apoptosis Post-ionizing Radiation (IR) in Breast Cancer in 3 Dimensional Culture and In Vivo (2007) (1)
p-nitrophenyl-beta-D-xyloside modulates proteoglycan synthesis and secretory differentiation in mouse mammary epithelial cell cultures. (1988) (1)
p-NITROPHENYL-p- D-XYLOSIDE MODULATES PROTEOGLYCAN SYNTHESIS AND SECRETORY DIFFERENTIATION IN MOUSE MAMMARY (1988) (1)
Review Myoepithelial cells: good fences make good neighbors (2005) (1)
Identification and targeting of a TACE-dependent autocrine loop which predicts poor prognosis in breast cancer - eScholarship (2005) (1)
Inhibition of vimentin or B1 integrin reverts morphology of prostate tumor cells grown in laminin-rich extracellular matrix gels and reduces tumor growth in vivo (2010) (1)
The solid-state signaling pathway from extracellular matrix to nuclear matrix: The critical role of three-dimensional architecture for functional differentiation (1997) (1)
Transition A Human Breast Cell Model of Preinvasive to Invasive (2008) (1)
Asking the Question of Why (2020) (1)
Abstract A113: The pattern of hMENA isoforms is regulated by TGF-β1 in pancreatic cancer and may predict patient outcome (2016) (1)
ASCORBIC ACID INHIBITS RNA-TUMOR REPLICATION AND INFECTIVITY (1979) (1)
Collagen-fibronectin interactions in normal and rous sarcoma virus-transformed avian tendon cells: Possible mechanisms for increased extracellular matrix turnover after transformation (1987) (1)
Inhibiting Vimentin or beta 1-integrin Reverts Prostate Tumor Cells in IrECM and Reduces Tumor Growth (2009) (1)
Mechanisms of disease: epithelial-mesenchymal transition and back again: does cellular plasticity fuel neoplastic progression? (2008) (1)
GLUCOSE METABOLISM IN NORMAL AND VIRUS-INFECTED CHICK CELLS IN CULTURE (1973) (1)
Cell-ECM mediated radiation response in breast cancer: β1 integrin as a potential molecular target (2003) (1)
Heeding a mentor's advice: A lesson in persistence (2011) (1)
Ser71 Phosphorylation Inhibits Actin-Binding of Profilin-1 and Its Apoptosis-Sensitizing Activity (2021) (1)
Deficiency of the p53/p63 target Perp alters mammary gland homeostasis and promotes cancer (2012) (1)
Abstract B62: Perturbed myoepithelial cell differentiation in BRCA mutation carriers and in DCIS (ductal carcinoma in situ) (2018) (1)
A breast cancer progression model: the importance of three-dimensional tissue architecture and metalloproteinases (2005) (1)
in Importance of context for inhibition of matrix metalloproteinases (2010) (0)
High-Level Expression of the Rat Whey Acidic Protein Gene Is Mediated by in the (0)
3D models of EGFR-dependent breast cancer: mechanisms of activation, drug response and resistance (2007) (0)
The influence of the microenvironment on the malignantphenotype (2000) (0)
The golgi associated calcium pump in human breast cancer (2009) (0)
Targeting cell-extracellular matrix (ECM) interactions to enhance radiation efficacy for breast cancer treatment (2005) (0)
ISD and Differentiation (2002) (0)
Studies on the mechanism of protein excretion in bacteria: the extracellular proteinase of a Sarcina strain (Coccus P). (1972) (0)
THE STRUCTURAL BASIS OF TISSUE SPECIFICITY IN NORMAL AND MALIGNANT BREAST: THE ROLE OF SIGNALLING FROM SURFACE RECEPTORS. (2000) (0)
Breast Cancer in Context: New Tools and Paradigms for the Millennium (2006) (0)
Membrane changes induced by treatment of mdck cells with tumor promoter 12 o tetradecanoyl phorbol 13 acetate as determined by fluorescence recovery after photo bleaching measurements (1983) (0)
Two molecular cytogenetic views of breast cancer (2000) (0)
ADENYLATES, PYRIDINE NUCLEOTIDE LEVELS NOT THE CAUSE OF DIFFERENCE IN GLYCOLYSIS BETWEEN NORMAL AND TRANSFORMED CELLS (1974) (0)
Health Detectives: Uncovering the Mysteries of Disease (LBNL Science at the Theater) (2012) (0)
Training in Mammary Gland Biology and Breast Cancer (2002) (0)
Undergraduate Training in Mammary Gland Biology and Breast Cancer (2005) (0)
Self-organization of mammary epithelial lineages is driven by differential E-cadherin activity. (2010) (0)
Hyaluronic acid Tenascin SPARC PLASMA MEMBRANE AND ECM ASSOCIATION THE ARCHITECTURE OF THE BASEMENT MEMBRANE THE INFLUENCE OF ECM ON CELL FUNCTION: MAMMARY GLAND AS A MODEL (2013) (0)
Abstract 5132: 14-3-3sigma coordinates breast tumor invasion by regulating cytoskeletal dynamics (2010) (0)
Communication between the cell membrane and the nucleus: role of protein compartmentalization. (1998) (0)
Global gene expression analysis indicates that multiple pathways are affected during growth arrest of non-malignant human mammary epithelial cells in three dimensional cell cultures (2005) (0)
Regulation of Cell- Generated Forces during Phenotypic Reversion by a Novel Laminin Chain in 3D Culture of Human Breast Tumor Cells (2013) (0)
Systems-level properties of EGFR/Ras/ERK signalling amplify local signals to generate gene expression plasticity (2018) (0)
Cell Biology: A Love Affair (2010) (0)
Fibrosis and Cancer: Do myofibroblasts come from epithelial EMT? (2006) (0)
Abstract A58: Cell motility in a basement membrane gel concentrates ECM around breast epithelial cells, a feature lost in malignant cells (2017) (0)
First articles published online (2009) (0)
423 Models to study breast cancer invasion and metastases: lessons from normal (2010) (0)
6th Pan Pacific Connective Tissue Societies Symposium (2006) (0)
AND PARACRINE REGULATION OF TISSUE-SPECIFIC FUNCTIONS (1989) (0)
High-Level Expression oftheRatWheyAcidic Protein GeneIs (1992) (0)
Generating a Fractal Microstructure of Laminin-111 to Signal to Cells. (2020) (0)
In vivo from Normal Phenotype in Three Dimensional Cultures and Cancer Cells , Inhibits Growth , and Distinguishes Malignant Integrin Inhibitory Antibody Induces Apoptosis of Breast 1 β (2006) (0)
Aloke Chatterjee (1940–2009) (2010) (0)
Differential phosphorylation of multiple AZU-1 isoforms in the HMT-3522 human breast tumor progression model (2001) (0)
Abstract A25: Cytometric atlas of the human breast: Comprehensive characterization reveals 12 distinct cell populations (2016) (0)
Genes and the Microenvironment: Two Faces of Breast Cancer (LBNL Science at the Theater) (2008) (0)
Faculty Opinions recommendation of Cell and fibronectin dynamics during branching morphogenesis. (2006) (0)
Abstract A54: A cellular and molecular atlas of the human breast for dissecting mechanisms of cell and tissue function (2018) (0)
arkeley Lab or UNIVERSITY CALIFORNIA CHEMICAL BIODYNAMICS DIVISION (2012) (0)
The microstructure of laminin-111 compensates for dystroglycan loss in functional differentiation of mammary epithelial cells (2019) (0)
1 GLUCOSE METABOLITE PATTERNS AS MARKERS OF FUNCTIONAL DIFFERENTIATION IN FRESHLY ISOLATED AND CULTURED MOUSE MAMMARY EPITHELIAL CELLS (2008) (0)
Lawrence Berkeley National Laboratory Recent Work Title New insight into the role of MMP 14 in metabolic balance Permalink (2016) (0)
Modulation of mammary epithelial cells from lactating mice to a prelactating state when cultured on floating collagen gels. (1980) (0)
scin-C inhibits extracellular matrix-mary epithelial cells lization of active regions using recombina (0)
Abstract A60: The hMENA Splicing Program: An important regulator of TGFβ1-driven EMT and invasiveness in pancreatic cancer (2015) (0)
Discovery of a New Cellular Motion and Its Relevance to Breast Cancer and Involution (2014) (0)
Abstract SY02-02: Interaction of MMPs with oncogenic signaling: Disruption of dynamic reciprocity and tissue polarity (2011) (0)
119 INVITED Why Do We Get So Few Cancers (2011) (0)
EMT and back again: does cellular plasticity fuel neoplastic progression? (2007) (0)
Raf-induced disrupts tissue architecture of human breast cells in three-dimensional culture and is necessary for tumor growth in vivo. (2010) (0)
A hierarchy of ECM-mediated signaling tissue-specific gene expression regulates tissue-specific gene expression (2010) (0)
Understanding and Modeling Aggressive ER+ Luminal Adenocarcinoma: Toward Effective Therapeutics (2018) (0)
Novel Image Analysis to Link Sub-Nuclear Distribution of Proteins with Cell Phenotype in Mammary Cancer (2003) (0)
CANCELLED Polo-like Kinase 1 is involved in invasion through extracellular matri x (2008) (0)
Characterization, isolation and cultivation of distinctive human breast cell populations (2003) (0)
Little is known about the dynamics of cancer cell death in response to therapy in the tumor microenvironment (2012) (0)
Of extracellular matrix, the genome and the microenvironment in breast cancer: No cell is an island (2008) (0)
Author response: Transient external force induces phenotypic reversion of malignant epithelial structures via nitric oxide signaling (2018) (0)
Faculty Opinions recommendation of Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion. (2007) (0)
TRITIATED- AND 14C-GLUCOSE IN NORMAL AND TRANSFORMED CHICK CELLS: UPTAKE, PENTOSE SHUNT AND ISOTOPE EFFECTS (1974) (0)
Faculty Opinions recommendation of Formation of perfused, functional microvascular tubes in vitro. (2006) (0)
Number : DAMD 17-001-0224 TITLE : Training in Mammary Gland Biology and Breast Cancer (0)
Cancer at the Cellular Level (1987) (0)
A Cell Culture Model for Understanding Estrogen Receptor Regulation in Normal and Malignant Cells. Addendum (1998) (0)
Award Number: DAMD17-02-1-0438 TITLE: Breast Cancer in Context: New Tools and Paradigms for the Millennium PRINCIPAL INVESTIGATOR: (2007) (0)
Faculty Opinions recommendation of Membrane type-1 matrix metalloproteinase confers aneuploidy and tumorigenicity on mammary epithelial cells. (2006) (0)
Lawrence Berkeley National Laboratory Recent Work Title Modeling Host-Pathogen Interactions in the Context of the Microenvironment : Three-Dimensional Cell Culture (2018) (0)
Abstract B86: A cytometric atlas of the human breast: Comprehensive characterization reveals 12 distinct cell populations (2015) (0)
Spatially Dissecting the Viscoelastic Recoil and Cell Shape Contributions of Actomyosin Stress Fiber Bundles (2010) (0)
2-DEOXYGLUCOSE COMPARED WITH AN UNCOUPLER OP OXIDATIVE PHOSPHORYLATION: EFFECTS ON GLUCOSE METABOLISM AND ADENYLATE RATIOS IN CHICK CELLS IN CULTURE (1974) (0)
Ov-src tyrosine kinase is expressed and active in sarcoma-free avian embryos microinjected with Rous sarcoma virus ( retrovirus / tumorigenicity / tyrosine phosphorylation ) (0)
Faculty Opinions recommendation of Anchorage of microtubule minus ends to adherens junctions regulates epithelial cell-cell contacts. (2009) (0)
Metabolic interactions between mammary epithelial cells and adipocytes of mice during the lactational cycle. (1980) (0)
628 The microenvironment and the genome in breast cancer: how tissue architecture informs (2010) (0)
Involvement of Two Novel Morphoregulatory Molecules in Breast Morphogenesis and Invasive Cancer (2002) (0)
Running Title: Influence of Extracellular Matrix on the Nucleus Title: Extracellular Matrix, Nuclear and Chromatin Structure and Gene Expression in Normal Tissues and Malignant Tumors: A Work in Progress Authors: (2006) (0)
Abstract 1035: hMENA splicing program and TGF-β1-mediated EMT in pancreatic cancer (2014) (0)
Epigenetic reversion of breast carcinoma phenotype is accompaniedby DNA sequestration (2006) (0)
Abstract 4277: Prosective cloning of highly invasive differentiated breast cancer cells (2010) (0)
Metabolic patterns as differentiated markers in mammary epithelial cells (1979) (0)
Rhamm-/- mice are defective in skin wound repair due to aberrant ERK1,2 signaling in fibroblast migration (2006) (0)
Extracellular Matrix Remodeling in Breast Branching Morphogenesis and Breast Cancer: The Double-Edged Sword (2005) (0)
Collagen-IV or laminin-1 regulate estrogen receptor alpha expression and function in mouse mammary epithelial cells (2003) (0)
Matrix metaloproteases as proto-oncogenes (1997) (0)
Epimorphin stimulates side-branching and alveolar development in the mouse mammary gland and is regulated by the endocrine hormones 17 β -estradiol and progesterone (2007) (0)
Angular Morhpomechanics in the Establishment of Multicellular Architecture (2012) (0)
Secretory pathway Ca2+_ATPase isoforms in mouse lactation and in human breast cancer (2007) (0)
Modeling prostate epithelial cancer cells in three-dimensional cultures in Matrigel. (2006) (0)
Abstract P1-05-20: Fluorescent Hyaluronan Probes Distinguish Heterogeneous Breast Cancer Cell Subsets and Predict their Invasive Behavior (2012) (0)
Extracellular Matrix (ECM) Guides Tissue-Specific Function & Developmental Processes (1992) (0)
Coordinated Expression of ECM-Degrading Proteinases and Their Inhibitors Regulates Functional Status of Mammary Epithelia During Involution (1991) (0)
Use of HA-Metal Nanoparticles to Identify and Characterize Tumorigenic Progenitor Cell Subsets in Breast Tumors (2006) (0)
Abstract #751: Predictive value of a gene-signature identified in 3D cultures in breast cancer treated with Docetaxel. (2009) (0)
Alterations in tissue structure and loss of coordinated growth and adhesion in breast cancer (1998) (0)
CANCELLED EMT and back again: does cellular plasticity fuel neoplasticprogressi on? (2007) (0)
Extracellular Matrix is Required for Milk Protein Gene Expression and Secretion in Mammary Epithelial Cells (1989) (0)
370 The metastasis-promoting protein, S100A4, regulates mammary branching morphogenesis (2010) (0)
EXTENSIVE COLLAGEN FIBERS IN THE EXTRACELLULAR MATRIX OF AVIAN TENDON CELLS IN MONOLAYER CULTURE (2013) (0)
CRADA Final Report: Identification of New Therapies with Potential for Treatment of Breast Cancer (2002) (0)
The ecology of tumor (2006) (0)
RADIOCHROMATOGRAPHIC ANALYSIS OF GLUCOSE METABOLISM IN NORMAL AND VIRUS-INFECTED CHICK CELLS IN CULTURES (1973) (0)
Mechanisms of Abnormal Cell-Extracellular Matrix Interactions in Human Breast Cancer. (1995) (0)
Program Schedule (2007) (0)
Regulation of enzymes involved in glycogen metabolism in murine mammary epithelial cells: relation to lactose synthesis. (1980) (0)
Embryonic Interactions with the v-src Oncogene: Normal Cell Growth and Endothelial Neoplasia (1989) (0)
Glucose and Cancer Cells (1974) (0)
Abstract 1494: The role of microenvironment in mammary epithelial cell plasticity (2011) (0)
Quantitative Model-Based Image Analysis of NuMa Distribution Links Nuclear Organization with Cell Phenotype (2001) (0)
METABOLIC COOPERATIVITY BETWEEN MAMMARY EPITHELIAL CELLS AND ADIPOCYEES OF MICE (1980) (0)
Cellulose Synthesis in Higher Plants (2014) (0)
Site-specific inductive and inhibitory activities of and orchestrate mammary gland branching (2010) (0)
Zena Werb (1945–2020) (2020) (0)
Comparison of the effects of a tumor promotor (TPA) and the activation of the src-specific protein kinase on chick cells in culture (1980) (0)
Zena Werb (1945–2020): Mourning the loss of a tissue microenvironment icon (2020) (0)
Successful Conclusion of the 8th PPCTSS (2009) (0)
The Use of a Human Breast Tumor Progression Series and a 3-D Culture Model to Determine if Nuclear Structure Could Provide a Molecular and Therapeutic Marker (2000) (0)
Lawrence Berkeley National Laboratory Recent Work Title FAM 83 family oncogenes are broadly involved in human cancers : an integrative multi-omics approach (2017) (0)

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