Minor J. Coon
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Minor J. Coon's Degrees
- PhD Biochemistry University of California, Berkeley
- Bachelors Chemistry University of California, Berkeley
Why Is Minor J. Coon Influential?
(Suggest an Edit or Addition)According to Wikipedia, Minor Jesser Coon was an American biochemist and Victor V Vaughan Distinguished University Professor Emeritus at the University of Michigan, Ann Arbor. He is best known for his research on cytochrome P-450 and as the co-discoverer of HMG-CoA, along with Bimal Kumar Bachhawat. He died on September 5, 2018, from complications due to Alzheimer's disease.
Minor J. Coon's Published Works
Published Works
- P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature. (1996) (2884)
- The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature. (1993) (1640)
- Cytochrome P450 (1993) (1119)
- The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature. (1991) (1056)
- The P450 gene superfamily: recommended nomenclature. (1987) (774)
- Oxygen activation by cytochrome P-450. (1980) (764)
- Cytochrome P-450. Multiplicity of isoforms, substrates, and catalytic and regulatory mechanisms. (1991) (652)
- The P450 superfamily: updated listing of all genes and recommended nomenclature for the chromosomal loci. (1989) (552)
- Role of hemoprotein P-450 in fatty acid omega-hydroxylation in a soluble enzyme system from liver microsomes. (1968) (527)
- Resolution of the cytochrome P-450-containing omega-hydroxylation system of liver microsomes into three components. (1969) (508)
- Purification and characterization of a unique isozyme of cytochrome P-450 from liver microsomes of ethanol-treated rabbits. (1982) (432)
- Properties of electrophoretically homogeneous phenobarbital-inducible and beta-naphthoflavone-inducible forms of liver microsomal cytochrome P-450. (1976) (417)
- Inactivation of key metabolic enzymes by mixed-function oxidation reactions: possible implication in protein turnover and ageing. (1983) (402)
- Phosphatidylcholine requirement in the enzymatic reduction of hemoprotein P-450 and in fatty acid, hydrocarbon, and drug hydroxylation. (1970) (385)
- Purified liver microsomal cytochrome P-450. Separation and characterization of multiple forms. (1975) (381)
- Cytochrome P450: nature's most versatile biological catalyst. (2005) (352)
- On the stoichiometry of the oxidase and monooxygenase reactions catalyzed by liver microsomal cytochrome P-450. Products of oxygen reduction. (1984) (313)
- Purified liver microsomal NADPH-cytochrome P-450 reductase. Spectral characterization of oxidation-reduction states. (1978) (307)
- Studies on hydroperoxide-dependent substrate hydroxylation by purified liver microsomal cytochrome P-450. (1976) (297)
- Microsomes, drug oxidations, and chemical carcinogenesis (1980) (266)
- Separate roles for FMN and FAD in catalysis by liver microsomal NADPH-cytochrome P-450 reductase. (1981) (248)
- Epoxidation of olefins by cytochrome P450: evidence from site-specific mutagenesis for hydroperoxo-iron as an electrophilic oxidant. (1998) (246)
- Metabolism of nitrosamines by purified rabbit liver cytochrome P-450 isozymes. (1985) (222)
- Immunochemical evidence for induction of the alcohol-oxidizing cytochrome P-450 of rabbit liver microsomes by diverse agents: ethanol, imidazole, trichloroethylene, acetone, pyrazole, and isoniazid. (1985) (208)
- Cytochrome P450: progress and predictions (1992) (204)
- Catalytic activity of cytochrome P-450 isozyme 3a isolated from liver microsomes of ethanol-treated rabbits. Oxidation of alcohols. (1982) (204)
- Identification of the high and low potential flavins of liver microsomal NADPH-cytochrome P-450 reductase. (1978) (202)
- Interactions of cytochrome P-450, NADPH-cytochrome P-450 reductase, phospholipid, and substrate in the reconstituted liver microsomal enzyme system. (1980) (197)
- Enzymatic ω-Oxidation I. ELECTRON CARRIERS IN FATTY ACID AND HYDROCARBON HYDROXYLATION (1966) (194)
- Induction of multiple forms of mouse liver cytochrome P-450. Evidence for genetically controlled de novo protein synthesis in response to treatment with beta-naphthoflavone or phenobarbital. (1976) (190)
- Peroxo-iron and oxenoid-iron species as alternative oxygenating agents in cytochrome P450-catalyzed reactions: switching by threonine-302 to alanine mutagenesis of cytochrome P450 2B4. (1996) (178)
- Hydrogen peroxide formation and stoichiometry of hydroxylation reactions catalyzed by highly purified liver microsomal cytochrome P-450. (1977) (172)
- Evidence that isoniazid and ethanol induce the same microsomal cytochrome P-450 in rat liver, an isozyme homologous to rabbit liver cytochrome P-450 isozyme 3a. (1986) (168)
- Role of isozymes of rabbit microsomal cytochrome P-450 in the metabolism of retinoic acid, retinol, and retinal. (1992) (165)
- Hydrocarbon oxidation by a bacterial enzyme system. I. Products of octane oxidation. (1963) (165)
- Preparation and properties of partially purified cytochrome P-450 and reduced nicotinamide adenine dinucleotide phosphate-cytochrome P-450 reductase from rabbit liver microsomes. (1974) (160)
- Properties of NADPH-cytochrome P-450 reductase purified from rabbit liver microsomes. (1979) (155)
- Structural features of liver microsomal NADPH-cytochrome P-450 reductase. Hydrophobic domain, hydrophilic domain, and connecting region. (1982) (154)
- Effect of superoxide generation and dismutation on hydroxylation reactions catalyzed by liver microsomal cytochrome P-450. (1971) (149)
- P-450 cytochromes: structure and function. (1987) (144)
- Enzymatic ω-Oxidation IV. PURIFICATION AND PROPERTIES OF THE ω-HYDROXYLASE OF PSEUDOMONAS OLEOVORANS (1970) (141)
- Comparison of six rabbit liver cytochrome P-450 isozymes in formation of a reactive metabolite of acetaminophen. (1983) (140)
- Highly purified detergent-solubilized NADPH-cytochrome P-450 reductase from phenobarbital-induced rat liver microsomes. (1974) (137)
- Cytochrome P450-Catalyzed Hydroxylation of Mechanistic Probes that Distinguish between Radicals and Cations. Evidence for Cationic but Not for Radical Intermediates (2000) (133)
- Hydroxylation of benzphetamine and other drugs by a solubilized form of cytochrome P-450 from liver microsomes: lipid requirement for drug demethylation. (1969) (132)
- Multiple mechanisms and multiple oxidants in P450-catalyzed hydroxylations. (2003) (129)
- Cytochrome P-450 purified to apparent homogeneity from phenobarbital-induced rabbit liver microsomes: catalytic activity and other properties. (1974) (129)
- Specificity in the activation and inhibition by flavonoids of benzo[a]pyrene hydroxylation by cytochrome P-450 isozymes from rabbit liver microsomes. (1981) (121)
- Alcohol-inducible cytochrome P-450IIE1 lacking the hydrophobic NH2-terminal segment retains catalytic activity and is membrane-bound when expressed in Escherichia coli. (1991) (119)
- Oxidation-reduction states of FMN and FAD in NADPH-cytochrome P-450 reductase during reduction by NADPH. (1982) (117)
- Subunit structure of rabbit muscle pyruvate kinase. (1969) (117)
- Enzymatic ω-Oxidation II. FUNCTION OF RUBREDOXIN AS THE ELECTRON CARRIER IN ω-HYDROXYLATION (1967) (117)
- Purified liver microsomal cytochrome P-450. Electron-accepting properties and oxidation-reduction potential. (1975) (117)
- Properties of a yeast cytochrome P-450-containing enzyme system which catalyzes the hydroxylation of fatty acids, alkanes, and drugs. (1973) (113)
- Immunochemical characterization of multiple forms of cytochrome P-450 in rabbit nasal microsomes and evidence for tissue-specific expression of P-450s NMa and NMb. (1990) (113)
- Fatty acid and hydrocarbon hydroxylation in yeast: role of cytochrome P-450 in Candida tropicalis. (1971) (112)
- Two forms of liver microsomal cytochrome P-450, P-450lm2 and P-450LM4 (rabbit liver). (1978) (112)
- Complete amino acid sequence and predicted membrane topology of phenobarbital-induced cytochrome P-450 (isozyme 2) from rabbit liver microsomes. (1983) (110)
- An analysis of the electron paramagnetic resonance spectrum of pseudomonas oleovorans rubredoxin. A method for determination of the liganids of ferric iron in completely rhombic sites. (1971) (108)
- Properties of a solubilized form of the cytochrome P-450-containing mixed-function oxidase of liver microsomes. (1970) (106)
- Spectral intermediates in the reaction of oxygen with purified liver microsomal cytochrome P-450. (1976) (105)
- Purification and characterization of two unique forms of cytochrome P-450 from rabbit nasal microsomes. (1988) (103)
- ENZYMATIC OMEGA-OXIDATION OF FATTY ACIDS. I. PRODUCTS OF OCTANOATE, DECONATE, AND LAURATE OXIDATION. (1964) (102)
- Olefin formation in the oxidative deformylation of aldehydes by cytochrome P-450. Mechanistic implications for catalysis by oxygen-derived peroxide (1991) (102)
- Role of a hydrophobic polypeptide in the N-terminal region of NADPH-cytochrome P-450 reductase in complex formation with P-450LM. (1979) (98)
- Enzymatic ω-Oxidation III. PURIFICATION AND PROPERTIES OF RUBREDOXIN, A COMPONENT OF THE ω-HYDROXYLATION SYSTEM OF PSEUDOMONAS OLEOVORANS (1968) (97)
- Properties of electrophoretically homogeneous constitutive forms of liver microsomal cytochrome P-450. (1981) (96)
- Comparative Structures of P-450 Cytochromes (1986) (93)
- Heme ligand replacement reactions of cytochrome P-450. Characterization of the bonding atom of the axial ligand trans to thiolate as oxygen. (1982) (92)
- Evidence for a homolytic mechanism of peroxide oxygen--oxygen bond cleavage during substrate hydroxylation by cytochrome P-450. (1980) (91)
- Catalysis by cytochrome P-450 of an oxidative reaction in xenobiotic aldehyde metabolism: deformylation with olefin formation. (1991) (91)
- Ethanol oxidation and toxicity: role of alcohol P-450 oxygenase. (1986) (90)
- Hydroxylation by the hydroperoxy-iron species in cytochrome P450 enzymes. (2004) (90)
- Enzymatic -oxidation. VI. Isolation of homogeneous reduced diphosphopyridine nucleotide-rubredoxin reductase. (1972) (90)
- Regio- and stereoselectivity of various forms of purified cytochrome P-450 in the metabolism of benzo[a]pyrene and (-) trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene as shown by product formation and binding to DNA. (1978) (87)
- Metabolism of all-trans, 9-cis, and 13-cis isomers of retinal by purified isozymes of microsomal cytochrome P450 and mechanism-based inhibition of retinoid oxidation by citral. (1996) (86)
- Effects of cytochrome b5 on cytochrome P-450-catalyzed reactions. Studies with manganese-substituted cytochrome b5. (1984) (86)
- Immunochemical identification of cytochrome P-450 isozyme 3a (P-450ALC) in rabbit nasal and kidney microsomes and evidence for differential induction by alcohol. (1986) (82)
- The enzymatic cleavage of beta-hydroxy-beta-methylglutaryl coenzyme A to acetoacetate and acetyl coenzyme A. (1955) (81)
- On the mechanism of action of cytochrome P-450. Oxidation and reduction of the ferrous dioxygen complex of liver microsomal cytochrome P-450 by cytochrome b5. (1984) (80)
- On the mechanism of action of cytochrome P-450. Evaluation of homolytic and heterolytic mechanisms of oxygen-oxygen bond cleavage during substrate hydroxylation by peroxides. (1981) (79)
- Expression of truncated forms of liver microsomal P450 cytochromes 2B4 and 2E1 in Escherichia coli: influence of NH2-terminal region on localization in cytosol and membranes. (1993) (77)
- Enzymatic ω-Oxidation V. FORMS OF PSEUDOMONAS OLEOVORANS RUBREDOXIN CONTAINING ONE OR TWO IRON ATOMS: STRUCTURE AND FUNCTION IN ω-HYDROXYLATION (1971) (76)
- Immunochemical evidence for a role of cytochrome P-450 in liver microsomal ethanol oxidation. (1984) (76)
- Two distinct electrophilic oxidants effects hydroxylation in cytochrome P-450-catalyzed reactions [20] (1998) (74)
- On the mechanism of action of cytochrome P450: evaluation of hydrogen abstraction in oxygen-dependent alcohol oxidation. (1994) (74)
- Immunochemical studies on two electrophoretically homogeneous forms of rabbit liver microsomal cytochrome P-450: P-450LM2 and P-450LM4. (1977) (74)
- HYDROCARBON OXIDATION BY A BACTERIAL ENZYME SYSTEM. II. COFACTOR REQUIREMENTS FOR OCTANOL FORMATION FROM OCTANE. (1963) (74)
- Amino-terminal sequence of phenobarbital-inducible cytochrome P-450 from rabbit liver microsomes: similarity to hydrophobic amino-terminal segments of preproteins. (1977) (74)
- Hydroxylation of prostaglandins by inducible isozymes of rabbit liver microsomal cytochrome P-450. Participation of cytochrome b5. (1982) (73)
- Regulation of rabbit cytochrome P450 2E1 expression in HepG2 cells by insulin and thyroid hormone. (1998) (70)
- Effects of conditions for reconstitution with cytochrome b5 on the formation of products in cytochrome P-450-catalyzed reactions. (1986) (70)
- Immunochemical studies on the metabolism of nitrosamines by ethanol-inducible cytochrome P-450. (1985) (69)
- Induction and tissue-specific expression of rabbit cytochrome P450IIE1 and IIE2 genes. (1989) (69)
- Position-specific oxygenation of benzo(a)pyrene by different forms of purified cytochrome P-450 from rabbit liver. (1975) (68)
- Cytochrome P450 2: peroxidative reactions of diversozymes. (1996) (68)
- Purification of liver microsomal cytochrome P-450 isozymes 3a and 6 from imidazole-treated rabbits. Evidence for the identity of isozyme 3a with the form obtained by ethanol treatment. (1984) (67)
- Kinetic isotope effects implicate two electrophilic oxidants in cytochrome p450-catalyzed hydroxylations. (2003) (67)
- Multiple activated oxygen species in P450 catalysis: contributions To specificity in drug metabolism. (1998) (63)
- Regioselective and stereoselective hydroxylation of R and S warfarin by different forms of purified cytochrome P-450 from rabbit liver. (1978) (62)
- Role of lysyl epsilon-amino groups in adenosine diphosphate binding and catalytic activity of pyruvate kinase. (1971) (61)
- ACETOACETYL COENZYME A AS INTERMEDIATE IN THE ENZYMATIC BREAKDOWN AND SYNTHESIS OF ACETOACETATE1 (1953) (60)
- The amino acid requirements of man. VI. The rôle of the caloric intake. (1954) (60)
- Organization and differential expression of two highly similar genes in the rabbit alcohol-inducible cytochrome P-450 subfamily. (1988) (58)
- The amino acid requirements of man. XI. The threonine and methionine requirements. (1955) (58)
- Enzymatic Breakdown and Synthesis of Acetoacetate (1953) (57)
- Characterization of the ω-hydroxylase of Pseudomonas oleovorans as a nonheme iron protein (1977) (57)
- ENZYMATIC OMEGA-OXIDATION OF FATTY ACIDS. II. SUBSTRATE SPECIFICITY AND OTHER PROPERTIES OF THE ENZYME SYSTEM. (1964) (57)
- Evaluation of norcarane as a probe for radicals in cytochome p450- and soluble methane monooxygenase-catalyzed hydroxylation reactions. (2002) (56)
- Identification of the omega-hydroxylase of Pseudomonas oleovorans as a nonheme iron protein requiring phospholipid for catalytic activity. (1974) (56)
- Kinetics of reduction of cytochrome P-450LM4 in a reconstituted liver microsomal enzyme system. (1979) (55)
- Further studies on the properties of liver propionyl coenzyme A holocarboxylase synthetase and the specificity of holocarboxylase formation. (1966) (55)
- On the mechanism of action of cytochrome P-450. Spectral intermediates in the reaction of P-450LM2 with peroxy compounds. (1980) (55)
- Ipso-substitution by cytochrome P450 with conversion of p-hydroxybenzene derivatives to hydroquinone: evidence for hydroperoxo-iron as the active oxygen species. (2002) (55)
- Omega oxygenases: nonheme-iron enzymes and P450 cytochromes. (2005) (55)
- Mechanism of action of pyruvate kinase. Role of sulfhydryl groups in catalytic activity as determined by disulfide interchange. (1972) (55)
- cDNA and derived amino acid sequence of ethanol-inducible rabbit liver cytochrome P-450 isozyme 3a (P-450ALC). (1987) (53)
- Genetic expression of aryl hydrocarbon hydroxylase induction. Genetic specificity resides in the fraction containing cytochromes P448 and P450. (1973) (53)
- The amino acid requirements of man. VII. General procedures; the tryptophan requirement. (1954) (53)
- Comparative study of two highly purified forms of liver microsomal cytochrome P-450: circular dichroism and other properties. (1979) (53)
- The purification and properties of beta-hydroxyisobutyric dehydrogenase. (1957) (52)
- Enzymatic oxidation. VII. Reduced diphosphopyridine nucleotide-rubredoxin reductase: properties and function as an electron carrier in hydroxylation. (1972) (51)
- Stereospecificity and Other Properties of Highly Purified β-Hydroxy-β-methylglutaryl Coenzyme A Cleavage Enzyme from Bovine Liver (1968) (50)
- On the mechanism of hydroxylation reactions catalyzed by cytochrome P-450. (1973) (49)
- Sedimentation and other properties of the reconstituted liver microsomal mixed-function oxidase system containing cytochrome P-450, reduced triphosphopyridine nucleotide-cytochrome P-450 reductase, and phosphatidylcholine. (1973) (48)
- Metabolic activation of 2,6-dichlorobenzonitrile, an olfactory-specific toxicant, by rat, rabbit, and human cytochromes P450. (1996) (48)
- Enzymatic carboxylation of beta-hydroxyisovaleryl coenzyme A. (1956) (48)
- Fatty Acid Synthetase from Pig Liver (1971) (48)
- The enzymatic synthesis of beta-aminoisobutyrate, a product of valine metabolism, and of beta-alanine, a product of beta-hydroxypropionate metabolism. (1957) (48)
- Replacement of active-site cysteine-436 by serine converts cytochrome P450 2B4 into an NADPH oxidase with negligible monooxygenase activity. (2002) (47)
- Hydrolysis of nucleoside diand triphosphates by crystalline preparations of yeast inorganic pyrophosphatase. (1960) (47)
- Coenzyme A thiol esters of isobutyric, methacrylic, and beta-hydroxyisobutyric acids as intermediates in the enzymatic degradation of valine. (1957) (47)
- Evidence that puriified liver microsomal cytochrome P-450 is a one-electron acceptor. (1977) (47)
- Simple, rapid, and highly efficient separation of amino acid phenylthiohydantoins by reversed-phase high-performance liquid chromatography. (1982) (47)
- cDNA and derived amino acid sequence of rabbit nasal cytochrome P450NMb (P450IIG1), a unique isozyme possibly involved in olfaction. (1991) (46)
- Mechanism-based inactivation of cytochrome P450 2B4 by aldehydes: relationship to aldehyde deformylation via a peroxyhemiacetal intermediate. (1997) (46)
- Enzymatic hydrolysis of the coenzyme a thiol esters of beta-hydroxypropionic and beta-hydroxyisobutyric acids. (1957) (46)
- Purification and properties of a shortened form of cytochrome P-450 2E1: deletion of the NH2-terminal membrane-insertion signal peptide does not alter the catalytic activities. (1991) (46)
- Hydrocarbon formation in the reductive cleavage of hydroperoxides by cytochrome P-450. (1987) (46)
- Subcellular localization, aggregation state, and catalytic activity of microsomal P450 cytochromes modified in the NH2-terminal region and expressed in Escherichia coli. (1995) (45)
- Properties of the oxygenated form of liver microsomal cytochrome P-450. (1983) (44)
- Characterization of the cytochrome P450 CYP2J4: expression in rat small intestine and role in retinoic acid biotransformation from retinal. (1998) (44)
- Tiglyl coenzyme A and alpha-methylacetoacetyl coenzyme A, intermediates in the enzymatic degradation of isoleucine. (1956) (44)
- Reductive beta-scission of the hydroperoxides of fatty acids and xenobiotics: role of alcohol-inducible cytochrome P-450. (1990) (42)
- Evidence for a role of a perferryl-oxygen complex, FeO3+, in the N-oxygenation of amines by cytochrome P450 enzymes. (1997) (41)
- Structural resemblance of cytochrome P-450 isolated from Pseudomonas putida and from rabbit liver microsomes. (1974) (41)
- Induction of cytochrome P-450 isozyme 3a (P-450IIE1) in rabbit olfactory mucosa by ethanol and acetone. (1990) (40)
- Membrane topology of microsomal cytochrome P-450: saturation transfer EPR and freeze-fracture electron microscopy studies. (1990) (40)
- Aromatization of a bicyclic steroid analog, 3-oxodecalin-4-ene-10-carboxaldehyde, by liver microsomal cytochrome P450 2B4. (1994) (40)
- Carboxylation of beta-methylcrotonyl coenzyme A by a purified enzyme from chicken liver. (1959) (39)
- Oxygen activation in the metabolism of lipids, drugs and carcinogens. (2009) (37)
- On the mechanism of action of cytochrome P-450. Role of peroxy spectral intermediates in substrate hydroxylation. (1981) (36)
- Inactivation of ethanol-inducible cytochrome P450 and other microsomal P450 isozymes by trans-4-hydroxy-2-nonenal, a major product of membrane lipid peroxidation. (1995) (36)
- On the mechanism of action of cytochrome P-450. Spectral intermediates in the reaction with iodosobenzene and its derivatives. (1989) (36)
- Steroid metabolism by rabbit olfactory-specific P450 2G1. (1994) (35)
- Biochemical Studies on Drug Metabolism: Isolation of Multiple Forms of Liver Microsomal Cytochrome P-450 (1977) (35)
- Isolation and heterologous expression of cloned cDNAs for two rabbit nasal microsomal proteins, CYP2A10 and CYP2A11, that are related to nasal microsomal cytochrome P450 form a. (1993) (35)
- Monoclonal antibodies to rabbit liver cytochrome P450 LM2 (1980) (35)
- The metabolic fate of the isopropyl group of leucine. (1950) (35)
- Selective mechanism-based inactivation of the major phenobarbital-inducible P-450 cytochrome from rabbit liver by phencyclidine and its oxidation product, the iminium compound. (1989) (34)
- beta-Hydroxy-beta-methylglutaryl coenzyme A deacylase. (1958) (33)
- Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco-specific carcinogen, by rabbit nasal microsomes and cytochrome P450s NMa and NMb. (1992) (32)
- Evolutionary and phylogenetic relationships of rubredoxin-containing microbes. (1971) (32)
- Chapter 6 – Microsomal Cytochrome P-450: A Central Catalyst in Detoxication Reactions (1980) (32)
- Purification and properties of P-450LM3b, a constitutive form of cytochrome P-450, from rabbit liver microsomes. (1979) (31)
- Promoter function and the role of cytokines in the transcriptional regulation of rabbit CYP2E1 and CYP2E2. (2000) (31)
- Catalytic activity and stereoselectivity of purified forms of rabbit liver microsomal cytochrome P-450 in the oxygenation of the (-) and (+) enantiomers of trans-7,8-dihydroxy-7,8-dihydrobenzo[alpha]pyrene. (1979) (30)
- Alcohol metabolism and toxicity: role of cytochrome P-450. (1984) (30)
- The amino acid requirements of man. X. The lysine requirement. (1955) (30)
- CARBON DIOXIDE FIXATION IN HEART EXTRACTS BY β-HYDROXYISOVALERYL COENZYME A1 (1954) (30)
- Oxidative cleavage of esters and amides to carbonyl products by cytochrome P450. (1995) (29)
- Thermodynamic properties of oxidation-reduction reactions of bacterial, microsomal, and mitochondrial cytochromes P-450: an entropy-enthalpy compensation effect. (1986) (29)
- Enzymatic conversion of beta-hydroxypropionate to malonic semialdehyde. (1959) (29)
- Drug and fatty acid hydroxylation by solubilized human liver microsomal cytochrome P-450-phospholipid requirement. (1975) (29)
- Multiple oxidants and multiple mechanisms in cytochrome P450 catalysis. (2003) (28)
- The 1980 Bernard B. Brodie award lecture. Drug metabolism by cytochrome P-450: progress and perspectives. (1981) (28)
- Rabbit nasal cytochrome P-450 NMa has high activity as a nicotine oxidase. (1990) (28)
- The amino acid requirements of man. IX. The phenylalanine requirement. (1955) (28)
- Analysis of interactions among purified components of the liver microsomal cytochrome P-450-containing monooxygenase system by second derivative spectroscopy. (1980) (28)
- Enzyme Ingenuity in Biological Oxidations: a Trail Leading to Cytochrome P450 (2002) (28)
- Membrane topology of cytochrome P450 2B4 in Langmuir-Blodgett monolayers. (1998) (27)
- Cytochrome P-450 isozymes 2 and 5 in rabbit lung and liver. Comparisons of structure and inducibility. (1987) (27)
- Properties of partially purified liver microsomal cytochrome P‐450: Acceptance of two electrons during anaerobic titration (1974) (27)
- Reconstitution of the cytochrome P-450-containing mixed-function oxidase system of liver microsomes. (1978) (27)
- On the amino acid sequence of cytochrome P-450 isozyme 4 from rabbit liver microsomes. (1984) (26)
- Structural features of isozyme 2 of liver microsomal cytochrome P-450. Identification of a highly conserved cysteine-containing peptide. (1982) (26)
- ENZYMATIC ACTIVATION OF BIOTIN. BIOTINYL ADENYLATE FORMATION. (1964) (25)
- Enzymatic omega-oxidation. IV. Purification and properties of the omega-hydroxylase of Pseudomonas oleovorans. (1970) (25)
- A study of the mechanism of O-phosphorylhydroxylamine synthesis catalyzed by pyruvate kinase. (1968) (25)
- Discrete species of activated oxygen yield different cytochrome P450 heme adducts from aldehydes. (1999) (25)
- Expression of alcohol-inducible rabbit liver cytochrome P-450 3a (P-450IIE1) in Saccharomyces cerevisiae with the copper-inducible CUP1 promoter. (1990) (24)
- Substituted pyridines: nonsteroidal inhibitors of human placental aromatase cytochrome P-450. (1992) (24)
- Studies on the conversion of radioactive leucine to acetoacetate. (1949) (24)
- Role of phospholipid in electron transfer in a reconstituted liver microsomal enzyme system containing cytochrome P-450. (1971) (24)
- Monoclonal antibodies to rabbit liver cytochrome P-450LM2 and cytochrome P-450LM4. (1982) (24)
- THE ENZYMATIC SYNTHESIS OF PROPIONYL COENZYME A HOLOCARBOXYLASE FROM D-BIOTINYL 5'-ADENYLATE AND THE APOCARBOXYLASE. (1965) (24)
- Reduction of alkyl hydroperoxides to alcohols: role of rubredoxin, an electron carrier in the bacterial hydroxylation of hydrocarbons. (1971) (23)
- N-terminal modifications that alter P450 membrane targeting and function. (1996) (23)
- BIOCHEMICAL STUDIES ON CYTOCHROME P‐450 SOLUBILIZED FROM LIVER MICROSOMES: PARTIAL PURIFICATION AND MECHANISM OF CATALYSIS * (1973) (22)
- Alcohol-inducible cytochrome P-450 (P-450ALC) (1987) (22)
- Purification and characterization of cytochrome P450 2E2 from hepatic microsomes of neonatal rabbits. (1991) (22)
- The rôle of formate in the biosynthesis of histidine. (1951) (22)
- Metabolic Activation of trans-4-Hydroxy-2-nonenal, a Toxic Product of Membrane Lipid Peroxidation and Inhibitor of P450 Cytochromes* (1997) (21)
- Metabolism of N-nitroso-2,6-dimethylmorpholine by isozymes of rabbit liver microsomal cytochrome P-450. (1985) (21)
- Propionyl-CoA holocarboxylase synthesis from biotinyl adenylate and the apocarboxylase in the presence of an activating enzyme (1963) (21)
- Enzymes of ketone body metabolism. I. Purification of an acetoacetate-synthesizing enzyme from ox liver. (1960) (21)
- "Hydroxylamine kinase" and pyruvic kinase. (1960) (21)
- Stereochemistry of the functional group determines the mechanism of aromatase inhibition by 6-bromoandrostenedione. (1987) (20)
- Identification of P-450ALC in microsomes from alcohol dehydrogenase-deficient deermice: contribution to ethanol elimination in vivo. (1988) (20)
- LIVER MICROSOMAL MEMBRANES: RECONSTITUTION OF THE HYDROXYLATION SYSTEM CONTAINING CYTOCHROME P-450* (1976) (20)
- Cytochromes P450 NMa, NMb (2G1), and LM4 (1A2) are differentially expressed during development in rabbit olfactory mucosa and liver. (1992) (20)
- Cytochrome P-450-dependent formation of ethylene from N-nitrosoethylamines. (1988) (20)
- Differences in the developmental expression of rabbit cytochromes P-450 2E1 and 2E2. (1991) (20)
- Studies on the identity of the heme-binding cysteinyl residue in rabbit liver microsomal cytochrome P-450 isozyme 2. (1985) (19)
- Enzymatic activation of carbon dioxide. I. Crystalline carbon dioxide-activating enzyme. (1958) (19)
- EPR spectrometry of cytochrome P450 2B4: effects of mutations and substrate binding. (2000) (19)
- The amino acid requirements of man. XII. The leucine and isoleucine requirements. (1955) (18)
- Abolition of oxygenase function, retention of NADPH oxidase activity, and emergence of peroxidase activity upon replacement of the axial cysteine-436 ligand by histidine in cytochrome P450 2B4. (2005) (18)
- Incorporation of the cytochrome P-450 monooxygenase system into large unilamellar liposomes using octylglucoside, especially for measurements of protein diffusion in membranes. (1984) (18)
- Alcohol oxidation by isozyme 3a of liver microsomal cytochrome P-450 (1983) (17)
- Metabolism of aflatoxin B1 by rabbit and rat nasal mucosa microsomes and purified cytochrome P450, including isoforms 2A10 and 2A11. (1995) (17)
- Purification and characterization of 7α-hydroxy-4-cholesten-3-one 12α-hydroxylase (1992) (17)
- The effect of epoxide hydratase on benzo[a]pyrene diol epoxide hydrolysis and binding to DNA and mixed-function oxidase proteins. (1981) (17)
- Stopped-flow spectrophotometric analysis of intermediates in the peroxo-dependent inactivation of cytochrome P450 by aldehydes. (2000) (16)
- Hydroxylation of benzo[a]pyrene and binding of (-)trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene metabolites to deoxyribonucleic acid catalyzed by purified forms of rabbit liver microsomal cytochrome P-450. Effect of 7,8-benzoflavone, butylated hydroxytoluene and ascorbic acid. (1980) (16)
- Magnetic resonance and catalytic studies of pyruvate kinase with essential sulfhydryl or lysyl epsilon-amino groups chemically modified. (1973) (16)
- Peroxidase-like activity of uncoupled cytochrome P450: studies with bilirubin and toxicological implications of uncoupling. (2012) (16)
- Properties of the tryptophan residue in rabbit liver microsomal cytochrome P-450 isozyme 2 as determined by fluorescence. (1985) (16)
- FATTY ACID ω-OXIDATION IN A SOLUBLE MICROSOMAL ENZYME SYSTEM CONTAINING P-450* (1969) (16)
- Desaturase reactions complicate the use of norcarane as a mechanistic probe. Unraveling the mixture of twenty-plus products formed in enzyme-catalyzed oxidations of norcarane. (2007) (14)
- THE ROLE OF ADENOSINE TRIPHOSPHATE IN THE ENZYMATIC ACTIVATION OF CARBON DIOXIDE1 (1957) (14)
- ω-1 and ω-2 hydroxylation of prostaglandins by rabbit hepatic microsomal cytochrome P-450 isozyme 6 (1985) (14)
- Bicarbonate- and hydroxylamine-dependent degradation of adenosine triphosphate. (1959) (14)
- Evaluation of the role of free hydroxyl radicals in the cytochrome P-450-catalyzed oxidation of benzene and cyclohexanol. (1985) (14)
- ENZYMATIC HYDROLYSIS OF THE COENZYME A THIOL ESTERS OF β-HYDROXYPROPIONIC AND β-HYDROXYISOBUTYRIC ACIDS (1957) (13)
- 19 P-450 Oxygenases in Lipid Transformation (1983) (13)
- Isolation and partial characterization of the gene for cytochrome P-450 3a (P-450ALC) and a second closely related gene. (1988) (13)
- The relation of alpha-methylbutyrate to isoleucine metabolism. I. Acetoacetate formation. (1952) (13)
- Expression of rabbit cytochrome P-450IIE2 in yeast and stabilization of the enzyme by 4-methylpyrazole. (1990) (13)
- Enzymes of fatty acid metabolism. IV. Preparation and properties of coenzyme A transferase. (1956) (12)
- Biosynthesis of histidine from radioactive acetate and glucose. (1954) (12)
- Biotin- and adenosine triphosphate-dependent activation of propionyl apocarboxylase. (1963) (11)
- Enzymic ω-oxidation: Stoichiometry of the ω-oxidation of fatty acids (1969) (11)
- The relation of alpha-methyl-butyrate to isoleucine metabolism. II. Propionate formation. (1952) (11)
- Purified Liver Microsomal Cytochrome P -450: Catalytic Mechanism and Characterization of Multiple Forms (1975) (11)
- Structure-function analysis of CYP2A10 and CYP2A11, P450 cytochromes that differ in only eight amino acids but have strikingly different activities toward testosterone and coumarin. (1994) (11)
- Role of alcohol P-450-oxygenase (APO) in microsomal ethanol oxidation. (1985) (11)
- Purification and characterization of 7 alpha-hydroxy-4-cholesten-3-one 12 alpha-hydroxylase. (1992) (11)
- Role of isosafrole as complexing agent and inducer of P-450LM4 in rabbit liver microsomes. (1982) (10)
- Role of phospholipid in the reconstituted liver microsomal mixed function oxidase system containing cytochrome P-450 and NADPH-cytochrome P-450 reductase. (1973) (10)
- 17 – Biochemical Studies on Chemical Carcinogenesis: Role of Multiple Forms of Liver Microsomal Cytochrome P-450 in the Metabolism of Benzo[a]pyrene and Other Foreign Compounds (1978) (10)
- On the possible relationship of cytochrome P-450 to alcohol metabolism: fundamental aspects of the microsomal hydroxylation system, including properties and interactions of the components. (1980) (9)
- Reduction of mevaldic acid to mevalonic acid by a partially purified enzyme from liver. (1961) (9)
- Enzymatic omega-oxidation. V. Forms of Pseudomonas oleovorans rubredoxin containing one or two iron atoms: structure and function in omega-hydroxylation. (1971) (9)
- Isolation and characterization of a novel cytochrome P-450-like pseudogene. (1986) (9)
- Extrahepatic microsomal forms: olfactory cytochrome P450 (1993) (9)
- Enzymic synthesis and reduction of malonyl semialdehyde-coenzyme A. (1960) (9)
- Biochemical characterization of highly purified cytochrome P-450 and other components of the mixed function oxidase system of liver microsomal membranes. (1975) (8)
- The amino acid requirements of man. VIII. The metabolic availability of the optical isomers of acetyltryptophan. (1955) (8)
- PURIFICATION OF MEMBRANE–BOUND OXYGENASES: ISOLATION OF TWO ELECTROPHORETICALLY HOMOGENEOUS FORMS OF LIVER MICROSOMAL CYTOCHROME P-450 (1977) (8)
- The NH2-terminal region of rabbit CYP2E1 is not essential for interaction with NADPH-cytochrome P450 reductase. (1994) (8)
- Products from enzyme-catalyzed oxidations of norcarenes. (2007) (8)
- Enzymatic omega-oxidation. II. Function of rubredoxin as the electron carrier in omega-hydroxylation. (1967) (7)
- Mobility and clusterlike organization of liposomal cytochrome P-450 LM2: saturation transfer EPR studies. (1982) (7)
- CHAPTER 7 – Role of Rubredoxin in Fatty Acid and Hydrocarbon Hydroxylation Reactions (1973) (7)
- Induction of P-450 cytochromes 2E2, 1A1, and 1A2 by imidazole in neonatal rabbits. (1992) (7)
- [28] Reductive cleavage of hydroperoxides by cytochrome P-450 (1990) (7)
- Oxidative aldehyde deformylation catalyzed by NADPH-cytochrome P450 reductase and the flavoprotein domain of neuronal nitric oxide synthase. (2005) (7)
- Functional components and mechanism of action of the resolved liver microsomal enzyme system catalyzing fatty acid, hydrocarbon and drug hydroxylation. (1972) (6)
- Enzymatic omega-oxidation. 3. Purification and properties of rubredoxin, a component of the omega-hydroxylation system of Pseudomonas oleovorans. (1968) (6)
- Enzymatic omega-oxidation. I. Electon carriers in fatty acid and hydrocarbon hydroxylation. (1966) (6)
- Evaluation of Norcarane as a Probe for Radicals in Cytochrome P450- and Soluble Methane Monooxygenase-Catalyzed Hydroxylation Reactions [J. Am. Chem. Soc. 2002, 124, 6879−6886]. (2006) (6)
- Characterization of the omega-hydroxylase of Pseudomonas oleovorans as a nonheme iron protein. (1977) (6)
- Fatty acid omega-hydroxylase (alkane hydroxylase) from Pseudomonas oleovorans. (1978) (6)
- Functional components of the liver microsomal enzyme system catalysing fatty acid, hydrocarbon and drug hydroxylation. (1971) (6)
- Genetic Expression of Aryl Hydrocarbon Hydroxylase Induction (2002) (5)
- PREDOMINANT ROLE OF ALCOHOL-INDUCIBLE P-450s IN OXIDATIVE DAMAGE (1990) (5)
- [115] β-Hydroxy-β-methylglutaryl-CoA cleavage enzyme (bovine liver) (1970) (5)
- [80] Synthesis of malonic semialdehyde, β-hydroxypropionate, and β-hydroxyisobutyrate (1963) (5)
- Radical intermediates in the catalytic cycles of cytochrome P-450. (1988) (5)
- ON THE MECHANISM OF HYDROXYLATION REACTIONS IN A RECONSTITUTED LIVER MICROSOMAL ENZYME SYSTEM CONTAINING CYTOCHROME P-450 (1972) (5)
- Terminal sequences of lysosome solubilized pig liver cytochrome b5 reductase. (1980) (5)
- Olefin formation in the oxidative deformylation of aldehydes by cytochrome P-450. Mechanistic implications for catalysis by oxygen-derived peroxide [Erratum to document cited in CA115(5):48632c] (1991) (4)
- CATALYTIC ACTIVITY AND STEREOSPECIFICITY OF PHENOBARBITAL-INDUCIBLE AND 5,6-BENZOFLAVONE-INDUCIBLE ISOZYMES OF LIVER MICROSOMAL CYTOCHROME P-450 IN THE OXYGENATION OF BENZO[a]-PYRENE AND trans-7,8-DIHYDROXY-7,8-DIHYDROBENZO[a]PYRENE (1980) (4)
- RESOLUTION OF MULTIPLE EQUILIBRIA IN BINDING OF SMALL MOLECULES TO CYTOCHROME P-450 LM (1980) (4)
- Purification and characterization of cytochromes P450 in rabbit nasal microsomes. (1991) (4)
- Interference by goat-derived anti-lymphocyte globulin in a double-antibody radioimmunoassay of digoxin. (1987) (4)
- Highly purified cytochrome P-450 from liver microsomal membranes: recent studies on the mechanism of catalysis. (1976) (4)
- Reductive cleavage of hydroperoxides by cytochrome P-450. (1990) (4)
- [27] Assays for cytochrome P-450 peroxygenase activity (1990) (4)
- Mechanistic studies with purified components of the liver microsomal hydroxylation system: spectral intermediates in reaction of cytochrome P-450 with peroxy compounds. (1979) (4)
- Fatty acid synthetase from pig liver. 1. Isolation of the enzyme complex and characterization of the component with oxidoreductase activity for alicyclic ketones. (1971) (4)
- Biochemical and Biophysical Research Communications: Preface (2005) (4)
- The enzymatic isomerization of alpha-methylvinylacetyl coenzyme A and the specificity of a bacterial alpha-methylcrotonyl coenzyme A carboxylase. (1960) (3)
- Irwin C. Gunsalus, versatile and creative scientist. (2003) (3)
- Role of cytochrome P-450 in hydrocarbon formation from xenobiotic and lipid hydroperoxides. (1988) (3)
- Peroxidative reactions of diversozymes 1 (1996) (3)
- Biochemical Properties of Cytochrome P‐450 in Relation to Steroid Oxygenation a (1985) (3)
- Mechanistic Studies with Purified Liver Microsomal Cytochrome P-450: Comparison of O 2 - and Peroxide-Supported Hydroxylation Reactions (1982) (3)
- Enzymatic synthesis of branched chain acids from amino acids. (1955) (3)
- SODA : the ICL interface for ODA document access (1990) (3)
- Molecular mechanisms of interactions between phospholipids and liver microsomal cytochrome P-450 LM2. (1982) (3)
- Radiometric assay for cytochrome P-450-catalyzed progesterone 16 alpha-hydroxylation and determination of an apparent isotope effect. (1987) (2)
- Epoxidation of olf.fins by cytochromk P450 possible rolf, for hydroperoxo iron as the direct oxidant (1997) (2)
- Vincent Massey (1926–2002) (2002) (2)
- Stereospecificity and other properties of highly purified beta-hydroxy-beta-methylglutaryl coenzyme A cleavage enzyme from bovine liver. (1968) (2)
- Assays for cytochrome P-450 peroxygenase activity. (1990) (2)
- COVALENT BINDING OF SAFROLE TO PURIFIED ISOZYMES OF RABBIT LIVER MICROSOMAL CYTOCHROME P-450 (1981) (2)
- Cytochrome P450 2E1 mRNA in the rat prostate: detection and quantitation by competitive reverse transcription and polymerase chain reaction. (1998) (2)
- Evidence for a Role of a Perferryl-Oxygen Complex, FeO 3 (cid:49) , in the N -Oxygenation of Amines by Cytochrome P450 Enzymes (1997) (1)
- Answer 1 to Rao Et Al. (1988) (1)
- [123] Enzymes of isovaleryl CoA metabolism (1962) (1)
- Kinetics of reduction of purified liver microsomal cytochrome P-450 in the reconstituted enzyme system studied by stopped flow spectrophotometry. (1979) (1)
- Amino acid metabolism. (1958) (1)
- Enzymatic activation of carbon dioxide. II. Role of biotin in the carboxylation of beta-hydroxyisovaleryl coenzyme A. (1958) (1)
- Studies on covalent binding of (-)trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene metabolites to cytochromes P-450 LM2 and LM4 and NADPH-cytochrome P-450 reductase. (1989) (1)
- SECOND DERIVATIVE SPECTROSCOPIC STUDIES OF THE ESSENTIAL COMPONENTS OF THE LIVER MICROSOMAL MONOOXYGENATION SYSTEM (1980) (1)
- Quantitation of cytochrome P-450 form 3a mRNA in tissues from untreated and ethanol-, acetone-, and imidazole-treated rabbits (1987) (1)
- MECHANISM OF ACTION OF CYTOCHROME P-450 STUDIED WITH PERACIDS AS OXYGEN DONORS1 (1979) (1)
- Extrahepatic identification of ethanol-inducible rabbit cytochrome P-450 isozyme 3a (1985) (1)
- omega-1 and omega-2 hydroxylation of prostaglandins by rabbit hepatic microsomal cytochrome P-450 isozyme 6. (1985) (1)
- Radical intermediates in peroxide-dependent reactions catalyzed by cytochrome P-450 (1987) (1)
- Special issue: Cytochrome P450 (2007) (1)
- Cytochrome P‐450: A Multifaceted Catalysta (1983) (1)
- CYTOCHROME P-450 REDUCTION BY FMN-DEPLETED RAT LIVER NADPH-CYTOCHROME P-450 REDUCTASE RECONSTITUTED WITH ARTIFICIAL FLAVINS (1980) (1)
- Ronald W. Estabrook: gifted scientist with the same versatile, energetic, and colorful qualities as cytochrome P450. (2003) (1)
- STUDIES ON THE ASSOCIATION OF P-450 LM2 WITH NADPH-CYTOCHROME P-450 REDUCTASE AND WITH TRYPTIC PEPTIDES DERIVED FROM THE REDUCTASE (1980) (1)
- Enzymic omega-oxidation: stoichiometry of the omega-oxidation of fatty acids. (1969) (1)
- cDNA and Derived Amino Acid Sequence of Rabbit Nasal Cytochrome P 450 NMb ( P 450 llGl ) , a Unique lsozyme Possibly Involved in Olfaction ’ (2003) (1)
- [61] Enzymes of branched-chain amino acid metabolism (1962) (1)
- Properties of cytochrome P-450 isozyme 3a: A unique form of P-450 from ethanol-treated rabbits (1982) (1)
- Cytochrome P450, a very hard mountain to climb: evidence for multiple functional species of activated oxygen (2002) (0)
- ENZYMATIC ACTIVATION OF CARBON DIOXIDE (2003) (0)
- Effect of epimers of 6-bromoandrostenedione on progesterone and androstenedione 16α-hydroxylation by rabbit liver microsomal cytochrome P-450 isozyme 3b (1985) (0)
- Terminal Sequences of Lysosome Solubilized Pig Liver Cytochrome b 5 (1980) (0)
- N-nitroso-2,6-dimethylmorpholine metabolism by liver microsomal cytochrome P-450 (1984) (0)
- Metabolism of nitrosamines by purified cytochrome P-450 isozymes from rabbit liver (1984) (0)
- Composition of the NH2-terminal region governs the targeting of expressed P450 to Escherichia coli cytosol or membranes (1992) (0)
- The Enzymic Synthesis of Branched‐Chain Acids (2009) (0)
- Hydroxylation of prostaglandins (PGs) at C18 (ω-2) and C19 (ω-1) by cytochrome P-450 isozyme 6 (I6) from liver of imidazole(Im)-, ethanol- and isosafrole-treated rabbits. Identification of novel PG-metabolites (1985) (0)
- I.C. Gunsalus : special issue (2003) (0)
- Cytochrome P-450: a multifaceted catalyst. (1983) (0)
- Howard Bishop Lewis. (1974) (0)
- nes by mixed-function oxidation rotein turnover and ageing (2016) (0)
- Cytochrome P-450 epitope typing in animals and humans with monoclonal antibodies to ethanol induced rat liver microsomal cytochrome P-450 (P-450et) (1986) (0)
- Mechanism of oxidations involving the cytochrome P450 peroxoiron complex as probed by site-specific mutagenesis (1997) (0)
- AUTOCATALYZED COVALENT BINDING OF 3H(-)t-7,8-DIOL BENZO(a)PYRENE TO MIXED-FUNCTION OXIDASE ENZYMES AND DNA: THE ROLE OF EPOXIDE HYDRATASE (1980) (0)
- Hydroxylation of Prostaglandins by Rabbit Hepatic Microsomal Cytochrome P-450 lsozyme 6 ’ (2003) (0)
- KINETIC STUDY OF CYTOCHROME P-450 LM4 REDUCTION IN A RECONSTITUTED LIVER MICROSOMAL ENZYME SYSTEM (1980) (0)
- Stereochemistry of 6-bromoandrostenedione determines the mode of aromatase inhibition (1986) (0)
- MEMBRANE TGPGLGGY OF MICROSGMAL CYTGCHROME P-450 : SATURATION TRANSFER EPR AND FREEZEFRACTURE ELECTRON MICROSCOPY STUDIES (2003) (0)
- 913 – EVIDENCE FOR DE NOVO SYNTHESIS OF CYTOCHROME P-448 IN THE “AROMATIC HYDROCARBON RESPONSIVE” MOUSE (1977) (0)
- COMPARISON OF INDUCIBLE AND CONSTITUTIVE FORMS OF MICROSOMAL P-450 AS TO STRUCTURE AND FUNCTION (1981) (0)
- SPECTRAL INTERMEDIATES OBSERVED IN THE CUMENE HYDROPEROXIDE-DEPENDENT HYDROXYLATION OF TOLUENE CATALYZED BY P-450 LM2 (1980) (0)
- An approach to the enzymatic synthesis of isoprenoid compounds. (1956) (0)
- Metabolism of phencyclidine and its oxidation product, the iminium compound, leads to destruction of specific rabbit liver microsomal P-450 cytochromes Osawa, Y. and M. J. Coon. Departments of Biological Chemistry and Pharmacology, The University of Michigan, Ann Arbor, MI 48109-0606 (1987) (0)
- Biochemical preparations, volume 9. (1962) (0)
- FATTY ACID AND HYDBCCAWCI N iYDF0XYLATION IN YEAST: ROLE OF CYTOCliBCME P-450 IN Candida tropicalis* (2003) (0)
- Role of cytochrome P-450 isozyme 3a in microsomal metabolism of three nasal carcinogens (1986) (0)
- Reductive 8-scission of the hydroperoxides of fatty acids and xenobiotics: Role of alcohol-inducible cytochrome P-450 (lipid peroxidation/isozymes of rabbit cytochrome P450/formation of 13-oxo-9,11-tridecadienoic acid/hydrocarbon formation in microsomal membranes/reductive cleavage of hydroperoxides (0)
- Structural resemblance of cytochrome P-450 isolated from and from rabbit liver microsomes (1974) (0)
- crassa. Because of the importance of peroxides in the production of mutations in microorganisms and as intermediates in the production of mutations by ultraviolet (2005) (0)
- Metabolism of /V-Nitroso-2,6-dimethylmorpholine by Isozymes of Rabbit Liver Microsomal Cytochrome P-4501 (2006) (0)
- Enzymes of fatty acid metabolism. III. Breakdown and synthesis of beta-keto fatty acids. (1956) (0)
- Intramolecular isotope effects favor a concerted mechanism for the cytochrome P-450-catalyzed oxidative deformylation of cyclohexane carboxaldehyde to give cyclohexene (1992) (0)
- ACETOACETATE RADIOACTIVE LEUCINE TO STUDIES ON THE CONVERSION OF (2003) (0)
- Mechanism based inactivation of rabbit liver microsomal cytochrome p 450 isozyme 2 by phencyclidine (1986) (0)
- [65] Synthesis of d-biotinyl 5′-adenylate (1970) (0)
- Inactivation of ethanol-inducible cytochrome P 450 and other microsomal P 450 isozymes by trans-4-hydroxy-2-nonenal , a major product of membrane lipid peroxidation ( alcohol-inducible cytochrome P 450 2 El / NADPH-cytochrome P 450 reductase / substrate protection against 4-hydroxynonenal ) (2005) (0)
- Vol.&O,No.4,1974 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNlCATlONS HIGHLY PURIFIED DETERGENT-SOLUBILIZED NADPH-CYTOCHROME P-450 REDUCTASE FROM PHENOBARBITAL-INDUCED RAT LIVER MICROSOMES" (2003) (0)
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