Minoti Apte
#104,213
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Medical researcher
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#4025
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Common Law
#203
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#220
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#1324
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#1586
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Minoti Apte's Degrees
- PhD Biochemistry University of Illinois Chicago
- Doctorate Medicine University of Illinois Chicago
Why Is Minoti Apte Influential?
(Suggest an Edit or Addition)According to Wikipedia, Minoti Vivek Apte is an Indian-born Australian pancreatology researcher and is the Director of Pancreatic Research Group at the University of South Wales and Ingham Institute for Applied Medical Research in Liverpool, New South Wales, Australia. She is also a classical Indian dancer and choreographer. Apte is notable for her many achievements in the field of pancreatic disease research, including becoming the first in the world to successfully isolate pancreatic stellate cells , the cells associated with pancreatic fibrogenesis. The effectiveness of this isolation method allowed her team to prove that PSCs’ close communication with cancerous cells contributes to the aggressiveness of pancreatic cancer, a major discovery that led the government of New South Wales to award her The Premier's Award for Woman of the Year in 2015.
Minoti Apte's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Pancreatic cancer (1988) (797)
- Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy (2014) (776)
- Pancreatic stellate cells are activated by proinflammatory cytokines: implications for pancreatic fibrogenesis (1999) (545)
- Chronic pancreatitis: challenges and advances in pathogenesis, genetics, diagnosis, and therapy. (2007) (508)
- Pancreatic stellate cells: partners in crime with pancreatic cancer cells. (2008) (419)
- Activation of pancreatic stellate cells in human and experimental pancreatic fibrosis. (1999) (394)
- A starring role for stellate cells in the pancreatic cancer microenvironment. (2013) (363)
- StellaTUM: current consensus and discussion on pancreatic stellate cell research (2011) (351)
- Pancreatic stellate cells respond to inflammatory cytokines: potential role in chronic pancreatitis (2002) (335)
- Role of pancreatic stellate cells in pancreatic cancer metastasis. (2010) (305)
- Rat pancreatic stellate cells secrete matrix metalloproteinases: implications for extracellular matrix turnover (2003) (272)
- Pancreatic stellate cells: a starring role in normal and diseased pancreas (2012) (262)
- Does alcohol directly stimulate pancreatic fibrogenesis? Studies with rat pancreatic stellate cells. (2000) (252)
- Pancreatic stellate cells and pancreatic cancer cells: an unholy alliance. (2008) (213)
- Inter‐ and intra‐tumoural heterogeneity in cancer‐associated fibroblasts of human pancreatic ductal adenocarcinoma (2019) (170)
- Endotoxin induced hepatic necrosis in rats on an alcohol diet (1987) (162)
- Dangerous liaisons: Pancreatic stellate cells and pancreatic cancer cells (2012) (134)
- Vitamin A inhibits pancreatic stellate cell activation: implications for treatment of pancreatic fibrosis (2005) (134)
- Acute pancreatitis (2015) (123)
- Mechanisms of alcoholic pancreatitis (2010) (120)
- Stellate Cell Activation in Alcoholic Pancreatitis (2003) (116)
- Pancreatic cancer and its stroma: a conspiracy theory. (2014) (116)
- The fibrosis of chronic pancreatitis: new insights into the role of pancreatic stellate cells. (2011) (112)
- Bacterial endotoxin: a trigger factor for alcoholic pancreatitis? Evidence from a novel, physiologically relevant animal model. (2007) (109)
- American Journal of Physiology: Gastrointestinal and Liver Physiology American Journal of Physiology: Heart and Circulatory Physi- QlQgY American Journal of Physiology: Regulatory, Integrative and Comparative Physiology American Journal of Physiology: Renal, Fluid and Electrolyte (2003) (108)
- Polymorphism in alcohol‐metabolizing enzymes, glutathione S‐transferases and apolipoprotein E and susceptibility to alcohol‐induced cirrhosis and chronic pancreatitis (2002) (103)
- Molecular mechanisms of pancreatitis: Current opinion (2008) (102)
- Stars and stripes in pancreatic cancer: role of stellate cells and stroma in cancer progression (2014) (101)
- Cell migration: a novel aspect of pancreatic stellate cell biology (2003) (99)
- Key role of pancreatic stellate cells in pancreatic cancer. (2016) (94)
- Pancreatic stellate cells produce acetylcholine and may play a role in pancreatic exocrine secretion (2010) (84)
- Hepatocyte growth factor inhibition: a novel therapeutic approach in pancreatic cancer (2016) (84)
- Pancreatic Stellate Cell Activation by Ethanol and Acetaldehyde: Is it Mediated by the Mitogen-Activated Protein Kinase Signaling Pathway? (2003) (81)
- Role of Alcohol Metabolism in Chronic Pancreatitis (2007) (78)
- Pancreatic stellate cell migration: role of the phosphatidylinositol 3-kinase(PI3-kinase) pathway. (2004) (75)
- New insights into alcoholic pancreatitis and pancreatic cancer (2009) (72)
- Cystic fibrosis genotypes and alcoholic pancreatitis (1998) (69)
- Contribution of microRNAs in understanding the pancreatic tumor microenvironment involving cancer associated stellate and fibroblast cells. (2015) (68)
- The Combination of Alcohol and Cigarette Smoke Induces Endoplasmic Reticulum Stress and Cell Death in Pancreatic Acinar Cells. (2017) (66)
- Battle‐scarred pancreas: Role of alcohol and pancreatic stellate cells in pancreatic fibrosis (2006) (64)
- The role of the hepatocyte growth factor/c-MET pathway in pancreatic stellate cell-endothelial cell interactions: antiangiogenic implications in pancreatic cancer. (2014) (64)
- Withdrawal of alcohol promotes regression while continued alcohol intake promotes persistence of LPS-induced pancreatic injury in alcohol-fed rats (2010) (63)
- Isolation of Quiescent Human Pancreatic Stellate Cells: A Promising in vitro Tool for Studies of Human Pancreatic Stellate Cell Biology (2010) (63)
- Recruitment and Activation of Pancreatic Stellate Cells from the Bone Marrow in Pancreatic Cancer: A Model of Tumor-Host Interaction (2011) (53)
- Non-Oxidative Metabolism of Ethanol by Rat Pancreatic Acini (2004) (47)
- Alcohol and cigarette smoke components activate human pancreatic stellate cells: implications for the progression of chronic pancreatitis. (2015) (47)
- Targeting the HGF/c-MET pathway: stromal remodelling in pancreatic cancer (2017) (47)
- The burning question: why is smoking a risk factor for pancreatic cancer? (2012) (47)
- Ethanol Augments PDGF-Induced NADPH Oxidase Activity and Proliferation in Rat Pancreatic Stellate Cells (2007) (45)
- Pancreatic stellate cells: Aiding and abetting pancreatic cancer progression. (2020) (43)
- 6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer. (2018) (43)
- Effects of ethanol and protein deficiency on pancreatic digestive and lysosomal enzymes. (1995) (40)
- Pancreatic Stellate Cells (2015) (39)
- Targeting the HGF/c-MET pathway in advanced pancreatic cancer: a key element of treatment that limits primary tumour growth and eliminates metastasis (2020) (34)
- Alcohol, signaling, and ECM turnover. (2010) (34)
- Alcohol-related pancreatic damage: mechanisms and treatment. (1997) (32)
- Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition (2020) (31)
- Pancreatic stellate cells: what's new? (2017) (31)
- Extracellular matrix composition significantly influences pancreatic stellate cell gene expression pattern: role of transgelin in PSC function. (2013) (27)
- Pancreas: Alcoholic pancreatitis—it's the alcohol, stupid (2009) (26)
- Alcoholic pancreatitis: A tale of spirits and bacteria. (2014) (23)
- Individual susceptibility to alcoholic pancreatitis (2008) (18)
- Targeting HGF/c-MET Axis in Pancreatic Cancer (2020) (18)
- Breaking the cycle: Targeting of NDRG1 to inhibit bi‐directional oncogenic cross‐talk between pancreatic cancer and stroma (2021) (16)
- Retinoid Signaling in Pancreatic Cancer, Injury and Regeneration (2011) (16)
- Oxidative stress: Does it ‘initiate’ hepatic stellate cell activation or only ‘perpetuate’ the process? (2002) (14)
- Fatty acid ethyl esters--alcohol's henchmen in the pancreas? (2006) (14)
- Multifunctional role of pancreatic stellate cells in pancreatic cancer (2019) (14)
- Employing pancreatic tumor γ-glutamyltransferase for therapeutic delivery. (2014) (13)
- Circulating pancreatic stellate (stromal) cells in pancreatic cancer-a fertile area for novel research. (2017) (12)
- Isolation of Quiescent Pancreatic Stellate Cells from Rat and Human Pancreas (2011) (11)
- Alcohol and the pancreas (1998) (10)
- Circulating tumour cells in pancreatic cancer: A systematic review and meta-analysis of clinicopathological implications. (2020) (9)
- Targeting Wnt/tenascin C-mediated cross talk between pancreatic cancer cells and stellate cells via activation of the metastasis suppressor NDRG1 (2022) (9)
- Current options for the diagnosis of chronic pancreatitis (2014) (9)
- Pancreatic stellate cells are activated in human and experimental pancreatic fibrosis (1998) (6)
- Signal transduction in alcohol-related diseases. (2005) (6)
- T1835 Alcohol Withdrawal Promotes Regression of Pancreatic Fibrosis via Induction of Pancreatic Stellate Cell (PSC) Apoptosis (2009) (6)
- A Team of Champions (2011) (5)
- Role of Pancreatic Stellate Cell-Derived Exosomes in Pancreatic Cancer-Related Diabetes: A Novel Hypothesis (2021) (5)
- Small extracellular vesicles (exosomes) and their cargo in pancreatic cancer: Key roles in the hallmarks of cancer. (2022) (5)
- Alcohol-Related Pancreatic Damage (1997) (4)
- Cancer Cells Pancreatic Stellate Cells : Partners in Crime with Pancreatic (2008) (4)
- Malnutrition as a cause of chronic pancreatitis: Myth dispelled? (2008) (4)
- The role of the hepatocyte growth factor/c-MET pathway in pancreatic stellate cell-endothelial cell interactions: Anti-angiogenic implications in Pancreatic Cancer (2014) (4)
- An Orthotopic Resectional Mouse Model of Pancreatic Cancer. (2020) (3)
- Pancreatic cancer: A multipronged approach to pancreatic cancer treatment (2016) (3)
- BACTERIAL ENDOTOXIN - A TRIGGER FACTOR FOR ALCOHOLIC PANCREATITIS (AP)? EVIDENCE FROM A NOVEL, PHYSIOLOGICALLY RELEVANT ANIMAL MODEL (2006) (2)
- PANCREATIC STELLATE CELLS STIMULATE PANCREATIC CANCER GROWTH AND METASTASIS: FINDINGS OF A NOVEL ORTHOTOPIC MODEL OF PANCREATIC CANCER (2006) (2)
- ALCOHOLIC PANCREATIC FIBROSIS: ROLE OF THE PHOSPHATIDYLINOSITOL-3 KINASE (PI3-K) AND PROTEIN KINASE C (PKC) PATHWAYS IN PANCREATIC STELLATE CELLS. (2004) (2)
- HGF/c-Met Inhibition as Adjuvant Therapy Improves Outcomes in an Orthotopic Mouse Model of Pancreatic Cancer (2021) (2)
- Alcohol, Reactive Oxygen Species, Pancreatitis and Pancreatic Cancer (2006) (2)
- Su1788 Pancreatic Fibrosis in Alcohol-Fed LPS Challenged Mice Is Regulated by the TLR4 Receptor (2013) (1)
- characterization of actin binding Mutagenesis analysis of human SM22 (2015) (1)
- American Pancreatic Association Frank Brooks Symposium (2020) (1)
- Current approaches to acute and chronic pancreatitis (2013) (1)
- 1133 PANCREATIC STELLATE CELL AND CANCER CELL DERIVED EXOSOMES IMPAIR BETA CELL FUNCTION: IMPLICATIONS FOR PANCREATIC CANCER RELATED DIABETES. (2020) (1)
- Abstract LB-395: Hepatocyte growth factor: a potential therapeutic target in pancreatic cancer (2011) (1)
- Reply letter to comments on: Targeting the HGF/c-MET pathway in advanced pancreatic cancer: a key element of treatment that limits primary tumour growth and eliminates metastasis (2020) (1)
- The influence of alcohol and cigarette smoke components on pancreatic stellate cell activation: Implications for the progression of chronic pancreatitis (2014) (1)
- Etiopathogenesis and Epidemiology of Alcohol‐Induced Acute Pancreatitis (2009) (1)
- Is the 5T mutation in intron 8 of the cystic fibrosis gene associated with alcoholic pancreatitis (1998) (1)
- PANCREATIC STELLATE CELLS STIMULATE ANGIOGENESIS IN PANCREATIC CANCER AND ACCOMPANY PANCREATIC CANCER CELLS TO DISTANT METASTATIC SITES (2008) (1)
- Pancreatic stellate cells are activated by tumour necrosis factor a (TNFA) — implications for pancreatic fibrogenesis (2000) (1)
- Pancreatic stellate cells produce collagen and other extracellular matrix proteins and exhibit a proliferative response to platelet-derived growth factor (PDGF) (1998) (1)
- 517 - World-First Identification of Circulating Pancreatic Stellate Cells in Metastatic Pancreatic Cancer (2018) (1)
- Smoking worsens the fibrosis of alcoholic chronic pancreatitis via activation of pancreatic stellate cells (2016) (1)
- Su1261: PANCREATIC CANCER-RELATED DIABETES: A HIGH FRUCTOSE DIET FED TO TRANSGENIC, KRASLSL-G12D/+; PDXCRE/+ (KC) MICE, IS ASSOCIATED WITH PANCREATIC STELLATE CELL ACTIVATION AND ACCELERATED CANCER PROGRESSION (2022) (0)
- Abstract 2868: Pancreatic tumor stromal cells express high levels of α-glutamyl transferase that may be employed to deliver a metabolism inhibitor to the tumor mass (2012) (0)
- Message from the Editor. (2014) (0)
- Pancreatic cancer: Stromal re-programming offers a novel therapeutic approach (2015) (0)
- Establishment of a novel adjuvant model of orthotopic pancreatic cancer: Effects of HGF-cMET inhibition on disease progression (2019) (0)
- Subject Index Vol. 23, 2005 (2006) (0)
- Targeting the urokinase plasminogen activator (uPA) pathway inhibits pancreatic cancer progression (2021) (0)
- Alcoholic pancreatitis in the modern era (2016) (0)
- The impact of diabetes on acute pancreatitis (2013) (0)
- PDFlib PLOP: PDF Linearization, Optimization, Protection Page inserted by evaluation version (1998) (0)
- PANCREATIC STELLATE CELL NADPH OXIDASE SYSTEM AND ITS ROLE IN MEDIATING PANCREATIC STELLATE CELL PROLIFERATION BY PLATELET DERIVED GROWTH FACTOR (PDGF) (2005) (0)
- From the editor. (2013) (0)
- Pancreatic cancer-related diabetes: Do pancreatic stellate cell and cancer cell derived exosomes play a role? (2020) (0)
- Gastroenterology Editorial Board (2006) (0)
- 184 HEPATOCYTE GROWTH FACTOR/ C-MET PATHWAY INHIBITION COMBINED WITH CHEMOTHERAPY RETARDS PRECURSOR PANINS AND POTENTIATES LOCAL IMMUNITY IN A TRANSGENIC MODEL OF EARLY PANCREATIC CANCER (2021) (0)
- The spectrum of alcohol related hepatic injury in previously healthy road traffic accident victims (1984) (0)
- CHRONIC ETHANOL FEEDING INDUCES TIMP2 SECRETION BY PANCREATIC STELLATE CELLS - ROLE IN ALCOHOLIC PANCREATIC FIBROSIS. (2004) (0)
- Pancreatic stellate cells: what do they tell us about chronic pancreatitis? (2017) (0)
- CHOLECYSTOKININ ACTIVATES INTRACELLULAR SIGNALLING PATHWAYS IN PANCREATIC STELLATE CELLS (2005) (0)
- Introduction for the IAP/APC symposium papers. (2013) (0)
- Metastatic phenotype and immunosuppressive tumour microenvironment in pancreatic ductal adenocarcinoma: Key role of the urokinase plasminogen activator (PLAU) (2022) (0)
- Oxidant stress induces the p38 mitogen activated protein kinase (p38 MAPK) signalling pathway in pancreatic stellate cells (2003) (0)
- The Healthy Pancreas Alcohol-related Pancreatic Damage Mechanisms and Treatment (0)
- Mo1371 INFLAMMATORY RESPONSE IN EXPERIMENTAL PANCREATITIS INDUCED BY ALCOHOL AND CIGARETTE SMOKE IS MEDIATED THROUGH ROS-STAT3-P62 SIGNALING PATHWAY (2020) (0)
- T1894 Abstinence Promotes Regression While Continued Alcohol Intake Promotes Persistence of LPS-Induced Pancreatic Injury in Alcohol-Fed Rats (2008) (0)
- Abstract A16: A novel therapeutic approach to inhibit the bidirectional oncogenic crosstalk between pancreatic cancer cells and the surrounding stroma (2019) (0)
- Reply letter to comments on: Targeting the HGF/c-MET pathway in advanced pancreatic cancer: a key element of treatment that limits primary tumour growth and eliminates metastasis (2020) (0)
- Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings. (2023) (0)
- Stromal remodeling in pancreatic cancer (2016) (0)
- S1820 Heat Shock Proteins Are Induced During Pancreatic Stellate Cell Activation in Pancreatic Cancer (2009) (0)
- ISOLATION OF QUIESCENT (NORMAL) HUMAN PANCREATIC STELLATE CELLS (HPSCS): A USEFUL IN VITRO TOOL FOR STUDIES OF HPSC BIOLOGY (2007) (0)
- Alcoholic Chronic Pancreatitis and the Impact of Alcohol and Smoking Cessation in Chronic Pancreatitis (2021) (0)
- Erratum. Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings. Diabetes 2023;72:433-448. (2023) (0)
- Epidemiology and Etiology of Alcohol‐Induced Pancreatitis (2018) (0)
- Pancreatic stellate cells are activated by cigarette smoke components and alcohol (2015) (0)
- Fibrogenesis in the Pancreas (2018) (0)
- Role of the microenvironment in chronic pancreatitis and pancreatic cancer (2016) (0)
- hronic Pancreatitis : Challenges and Advances in Pathogenesis , enetics , Diagnosis , and Therapy (2007) (0)
- Pancreatic Stellate Cells (PSCs): a starring role in pancreatitis and pancreatic cancer (2013) (0)
- 1041 Both Pancreatic Cancer and Pancreatic Stellate Cells Express High Levels of Gamma-glutamyl Transferase That May Be Employed to Deliver a Metabolism Inhibitor to the Tumour Mass (2012) (0)
- Alcohol, smoking and pancreas (2016) (0)
- What’s New in Pancreatic Stellate Cell Biology? (2004) (0)
- Message from editor. (2018) (0)
- ABSTINENCE PROMOTES REGRESSION WHILE CONTINUED ALCOHOL INTAKE PROMOTES PERSISTENCE OF LPS-INDUCED PANCREATIC INJURY IN ALCOHOL-FED RATS (2008) (0)
- Inhibition of both the ligand and receptor of the hepatocyte growth factor/c-MET pathway, in combination with chemotherapy, retards progression of PanIN lesions in KPC mice (2020) (0)
- In memoriam: Max G. Bachem, MD, PhD, Dr.hc Professor for Clinical Chemistry, 1952-2014. (2014) (0)
- Battle-scarred pancreas: Role of pancreatic stellate cells (2012) (0)
- Editorial (2010) (0)
- Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases (2022) (0)
- calcium and reactive oxygen species intermittent hypoxia in PC12 cells: involvement of Facilitation of dopamine and acetylcholine release by (2015) (0)
- HEAT SHOCK PROTEINS ARE DIFFERENTIALLY REGULATED DURING PANCREATIC STELLATE CELL ACTIVATION (2008) (0)
- Editorial Board (2012) (0)
- R OLE OF THE MICROENVIRONMENT IN CHRONIC PANCREATITIS AND PANCREATIC CANCER (2016) (0)
- Asian-Oceanic Pancreatic Association: conception to actuality. (2005) (0)
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Minoti Apte is affiliated with the following schools:
