Miriam Cnop
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Belgian researcher and physician
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Why Is Miriam Cnop Influential?
(Suggest an Edit or Addition)According to Wikipedia, Miriam Cnop is a Belgian researcher and physician specializing in diabetology. She is Professor of Medicine at Université Libre de Bruxelles and Clinical Director of Erasmus Hospital’s Endocrinology Department. Her work centered on type 2 diabetes, in particular mechanisms of lipotoxicity using human islets of Langerhans and human induced pluripotent stem cell-derived β Cells. She is an associate member of the Royal Academy of Medicine of Belgium. In 2013, her work was awarded the Oskar Minkowski prize from the European Association for the Study of Diabetes.
Miriam Cnop's Published Works
Published Works
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (2012) (2913)
- Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex (2003) (1449)
- Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities. (2005) (1420)
- The role for endoplasmic reticulum stress in diabetes mellitus. (2008) (1067)
- Endoplasmic reticulum stress, obesity and diabetes. (2012) (569)
- Initiation and execution of lipotoxic ER stress in pancreatic β-cells (2008) (561)
- Inverse relationship between cytotoxicity of free fatty acids in pancreatic islet cells and cellular triglyceride accumulation. (2001) (542)
- Free Fatty Acids and Cytokines Induce Pancreatic β-Cell Apoptosis by Different Mechanisms: Role of Nuclear Factor-κB and Endoplasmic Reticulum Stress (2004) (527)
- The concurrent accumulation of intra-abdominal and subcutaneous fat explains the association between insulin resistance and plasma leptin concentrations : distinct metabolic effects of two fat compartments. (2002) (447)
- The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients (2007) (392)
- The Human Pancreatic Islet Transcriptome: Expression of Candidate Genes for Type 1 Diabetes and the Impact of Pro-Inflammatory Cytokines (2012) (388)
- DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients (2012) (373)
- Beta-cell function is a major contributor to oral glucose tolerance in high-risk relatives of four ethnic groups in the U.S. (2002) (296)
- Selective Inhibition of Eukaryotic Translation Initiation Factor 2α Dephosphorylation Potentiates Fatty Acid-induced Endoplasmic Reticulum Stress and Causes Pancreatic β-Cell Dysfunction and Apoptosis* (2006) (296)
- The atherogenic lipoprotein profile associated with obesity and insulin resistance is largely attributable to intra-abdominal fat. (2003) (290)
- Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress. (2004) (282)
- Expression of adiponectin receptors in pancreatic beta cells. (2003) (268)
- Pancreatic β-cells in type 1 and type 2 diabetes mellitus: different pathways to failure (2020) (263)
- RNA Sequencing Identifies Dysregulation of the Human Pancreatic Islet Transcriptome by the Saturated Fatty Acid Palmitate (2014) (225)
- The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation (2010) (208)
- Glucagon-Like Peptide-1 Agonists Protect Pancreatic β-Cells From Lipotoxic Endoplasmic Reticulum Stress Through Upregulation of BiP and JunB (2009) (201)
- Palmitate induces a pro-inflammatory response in human pancreatic islets that mimics CCL2 expression by beta cells in type 2 diabetes (2010) (199)
- Fatty acids and glucolipotoxicity in the pathogenesis of Type 2 diabetes. (2008) (191)
- Ubiquitin Fold Modifier 1 (UFM1) and Its Target UFBP1 Protect Pancreatic Beta Cells from ER Stress-Induced Apoptosis (2011) (155)
- GLIS3, a Susceptibility Gene for Type 1 and Type 2 Diabetes, Modulates Pancreatic Beta Cell Apoptosis via Regulation of a Splice Variant of the BH3-Only Protein Bim (2013) (155)
- A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis (2015) (152)
- Endoplasmic reticulum stress and eIF2α phosphorylation: The Achilles heel of pancreatic β cells (2017) (151)
- Causes and cures for endoplasmic reticulum stress in lipotoxic β‐cell dysfunction (2010) (150)
- PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Interferon-γ–Induced Pancreatic β-Cell Apoptosis (2009) (135)
- ER Stress in Pancreatic β Cells: The Thin Red Line Between Adaptation and Failure (2010) (134)
- Is there a role for locally produced interleukin-1 in the deleterious effects of high glucose or the type 2 diabetes milieu to human pancreatic islets? (2005) (133)
- Low density lipoprotein can cause death of islet beta-cells by its cellular uptake and oxidative modification. (2002) (132)
- - Cell Function Is a Major Contributor to Oral Glucose Tolerance in High-Risk Relatives of Four Ethnic Groups in the U . (2002) (128)
- Recent insights into mechanisms of β-cell lipo- and glucolipotoxicity in type 2 diabetes. (2020) (127)
- Death Protein 5 and p53-Upregulated Modulator of Apoptosis Mediate the Endoplasmic Reticulum Stress–Mitochondrial Dialog Triggering Lipotoxic Rodent and Human β-Cell Apoptosis (2012) (117)
- Increased dietary fat promotes islet amyloid formation and beta-cell secretory dysfunction in a transgenic mouse model of islet amyloid. (2003) (112)
- tRNA Methyltransferase Homolog Gene TRMT10A Mutation in Young Onset Diabetes and Primary Microcephaly in Humans (2013) (108)
- Discovery of the gut microbial signature driving the efficacy of prebiotic intervention in obese patients (2020) (108)
- Functional genomic analysis of frataxin deficiency reveals tissue-specific alterations and identifies the PPARγ pathway as a therapeutic target in Friedreich’s ataxia (2009) (100)
- Transcriptional Regulation of the Endoplasmic Reticulum Stress Gene Chop in Pancreatic Insulin-Producing Cells (2007) (95)
- Progressive loss of beta-cell function leads to worsening glucose tolerance in first-degree relatives of subjects with type 2 diabetes. (2007) (92)
- Lean non-alcoholic fatty liver disease (Lean-NAFLD): a major cause of cryptogenic liver disease. (2011) (91)
- Transient Oxidative Stress Damages Mitochondrial Machinery Inducing Persistent β-Cell Dysfunction* (2009) (90)
- Type 2 diabetes mellitus—an autoimmune disease? (2013) (86)
- PTPN 2 , a candidate gene for type 1 diabetes , modulates interferon-gamma-induced pancreatic beta-cell apoptosis (2009) (83)
- An update on lipotoxic endoplasmic reticulum stress in pancreatic beta-cells. (2008) (80)
- Heterozygous RFX6 protein truncating variants are associated with MODY with reduced penetrance (2017) (79)
- Islet amyloid develops diffusely throughout the pancreas before becoming severe and replacing endocrine cells. (2001) (78)
- Pancreatic α Cells are Resistant to Metabolic Stress-induced Apoptosis in Type 2 Diabetes (2015) (76)
- Diabetes and Pancreatic Exocrine Dysfunction Due to Mutations in the Carboxyl Ester Lipase Gene-Maturity Onset Diabetes of the Young (CEL-MODY) (2011) (75)
- Longevity of human islet α‐ and β‐cells (2011) (74)
- Loss of PPARγ in immune cells impairs the ability of abscisic acid to improve insulin sensitivity by suppressing monocyte chemoattractant protein-1 expression and macrophage infiltration into white adipose tissue (2008) (73)
- Central role and mechanisms of β‐cell dysfunction and death in friedreich ataxia–associated diabetes (2012) (71)
- Deletion of C/EBP homologous protein (Chop) in C57Bl/6 mice dissociates obesity from insulin resistance (2012) (67)
- Pancreatic β-cell tRNA hypomethylation and fragmentation link TRMT10A deficiency with diabetes (2018) (65)
- Link between gut microbiota and health outcomes in inulin -treated obese patients: Lessons from the Food4Gut multicenter randomized placebo-controlled trial. (2020) (64)
- Diabetes in Friedreich Ataxia (2013) (63)
- A Missense Mutation in PPP1R15B Causes a Syndrome Including Diabetes, Short Stature, and Microcephaly (2015) (62)
- Endocytosis of low-density lipoprotein by human pancreatic beta cells and uptake in lipid-storing vesicles, which increase with age. (2000) (59)
- Sex-specific regulation of collagen I and III expression by 17&bgr;-Estradiol in cardiac fibroblasts: role of estrogen receptors (2018) (59)
- In vitro use of free fatty acids bound to albumin: A comparison of protocols. (2015) (58)
- Modulation of Autophagy Influences the Function and Survival of Human Pancreatic Beta Cells Under Endoplasmic Reticulum Stress Conditions and in Type 2 Diabetes (2019) (57)
- Unveiling a common mechanism of apoptosis in β-cells and neurons in Friedreich's ataxia. (2015) (55)
- Enhanced signaling downstream of ribonucleic Acid-activated protein kinase-like endoplasmic reticulum kinase potentiates lipotoxic endoplasmic reticulum stress in human islets. (2010) (54)
- Thrombospondin 1 protects pancreatic β-cells from lipotoxicity via the PERK–NRF2 pathway (2016) (50)
- Mild endoplasmic reticulum stress augments the proinflammatory effect of IL-1β in pancreatic rat β-cells via the IRE1α/XBP1s pathway. (2012) (47)
- Persistent or Transient Human β Cell Dysfunction Induced by Metabolic Stress: Specific Signatures and Shared Gene Expression with Type 2 Diabetes. (2020) (46)
- Role of the saturated nonesterified fatty acid palmitate in beta cell dysfunction. (2013) (45)
- Improving glycemic control in critically ill patients: personalized care to mimic the endocrine pancreas (2018) (45)
- Troglitazone does not protect rat pancreatic beta cells against free fatty acid-induced cytotoxicity. (2002) (45)
- Low Density Lipoprotein Binding and Uptake by Human and Rat Isletβ Cells. (1997) (43)
- Beta cell imaging – a key tool in optimized diabetes prevention and treatment (2014) (43)
- Pro-inflammatory cytokines induce cell death, inflammatory responses, and endoplasmic reticulum stress in human iPSC-derived beta cells (2020) (42)
- Loss of PPAR gamma in immune cells impairs the ability of abscisic acid to improve insulin sensitivity by suppressing monocyte chemoattractant protein-1 expression and macrophage infiltration into white adipose tissue. (2008) (40)
- High glucose induces dysfunction in insulin secretory cells by different pathways: a proteomic approach. (2010) (39)
- Palmitate-induced lipotoxicity alters acetylation of multiple proteins in clonal β cells and human pancreatic islets (2017) (39)
- JunB protects β-cells from lipotoxicity via the XBP1–AKT pathway (2014) (37)
- Pancreatic β-cell protection from inflammatory stress by the endoplasmic reticulum proteins thrombospondin 1 and mesencephalic astrocyte-derived neutrotrophic factor (MANF) (2017) (37)
- Endoplasmic reticulum stress sensitizes pancreatic beta cells to interleukin-1β-induced apoptosis via Bim/A1 imbalance (2013) (36)
- Pathological β-Cell Endoplasmic Reticulum Stress in Type 2 Diabetes: Current Evidence (2021) (36)
- Interindividual Heterogeneity of SGLT2 Expression and Function in Human Pancreatic Islets (2020) (35)
- Phenylpropenoic Acid Glucoside from Rooibos Protects Pancreatic Beta Cells against Cell Death Induced by Acute Injury (2016) (34)
- Phenylpropenoic acid glucoside augments pancreatic beta cell mass in high-fat diet-fed mice and protects beta cells from ER stress-induced apoptosis. (2014) (33)
- Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 (2016) (33)
- The effect of apolipoprotein E deficiency on islet amyloid deposition in human islet amyloid polypeptide transgenic mice (2003) (33)
- YIPF5 mutations cause neonatal diabetes and microcephaly through endoplasmic reticulum stress (2020) (33)
- Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652 (2016) (31)
- Exenatide induces frataxin expression and improves mitochondrial function in Friedreich ataxia. (2019) (31)
- Low density lipoprotein binding and uptake by human and rat islet beta cells. (1997) (30)
- TIGER: The gene expression regulatory variation landscape of human pancreatic islets (2021) (30)
- Exercise training protects human and rodent β cells against endoplasmic reticulum stress and apoptosis (2017) (29)
- BCL-6: a possible missing link for anti-inflammatory PPAR-δ signalling in pancreatic beta cells (2006) (29)
- Stearoyl CoA desaturase is a gatekeeper that protects human beta cells against lipotoxicity and maintains their identity (2019) (26)
- Towards a Functional Cure for Diabetes Using Stem Cell-Derived Beta Cells: Are We There Yet? (2021) (26)
- Combined transcriptome and proteome profiling of the pancreatic β-cell response to palmitate unveils key pathways of β-cell lipotoxicity (2020) (25)
- BCL-6: a possible missing link for anti-inflammatory PPAR-delta signalling in pancreatic beta cells. (2006) (24)
- PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma- induced pancreatic beta-cell apoptosis Running title: PTPN2 regulates cytokine-induced β-cell death. (2009) (24)
- Oleate-induced beta cell dysfunction and apoptosis: a proteomic approach to glucolipotoxicity by an unsaturated fatty acid. (2011) (23)
- Prebiotic dietary fibre intervention improves fecal markers related to inflammation in obese patients: results from the Food4Gut randomized placebo-controlled trial (2021) (23)
- Neonatal hemochromatosis and Martinez-Frias syndrome of intestinal atresia and diabetes mellitus in a consanguineous newborn. (2010) (22)
- Inhibition of Rho-associated kinases suppresses cardiac myofibroblast function in engineered connective and heart muscle tissues. (2019) (22)
- Inflammatory stress in islet &bgr;‐cells: therapeutic implications for type 2 diabetes? (2018) (22)
- Guanabenz Sensitizes Pancreatic &bgr; Cells to Lipotoxic Endoplasmic Reticulum Stress and Apoptosis (2017) (20)
- Prebiotic effect on mood in obese patients is determined by the initial gut microbiota composition: A randomized, controlled trial (2021) (19)
- Stearic acid at physiologic concentrations induces in vitro lipotoxicity in circulating angiogenic cells. (2017) (18)
- Comparative pharmacoscintigraphic and pharmacokinetic evaluation of two new formulations of inhaled insulin in type 1 diabetic patients. (2012) (18)
- Molecular genetics of the transcription factor GLIS3 identifies its dual function in beta cells and neurons. (2017) (18)
- High‐throughput screening and bioinformatic analysis to ascertain compounds that prevent saturated fatty acid‐induced &bgr;‐cell apoptosis (2017) (17)
- DNAJC3 deficiency induces β-cell mitochondrial apoptosis and causes syndromic young-onset diabetes. (2021) (14)
- Specific gut microbial, biological, and psychiatric profiling related to binge eating disorders: A cross-sectional study in obese patients. (2020) (14)
- Beneficial Outcomes of Sleeve Gastrectomy in a Morbidly Obese Patient With Bardet-Biedl Syndrome (2017) (13)
- Detection and quantification of beta cells by PET imaging: why clinical implementation has never been closer (2018) (12)
- The transcription factor B-cell lymphoma (BCL)-6 modulates pancreatic {beta}-cell inflammatory responses. (2011) (12)
- Fostering improved human islet research: a European perspective (2019) (12)
- Perioperative Management of Oral Glucose-lowering Drugs in the Patient with Type 2 Diabetes. (2020) (11)
- The tRNA Epitranscriptome and Diabetes: Emergence of tRNA Hypomodifications as a Cause of Pancreatic β-Cell Failure. (2019) (11)
- The KINGS Ins2+/G32S Mouse: A Novel Model of β-Cell Endoplasmic Reticulum Stress and Human Diabetes (2020) (10)
- The KINGS Ins2+/G32S Mouse: A Novel Model of β-Cell Endoplasmic Reticulum Stress and Human Diabetes (2020) (10)
- tRNA Biology in the Pathogenesis of Diabetes: Role of Genetic and Environmental Factors (2021) (10)
- CoDE-seq, an augmented whole-exome sequencing, enables the accurate detection of CNVs and mutations in Mendelian obesity and intellectual disability (2018) (10)
- Integration of single-cell datasets reveals novel transcriptomic signatures of β-cells in human type 2 diabetes (2020) (9)
- The position of single-base deletions in the VNTR sequence of the carboxyl ester lipase (CEL) gene determines proteotoxicity (2020) (9)
- Circulating unmethylated CHTOP and INS DNA fragments provide evidence of possible islet cell death in youth with obesity and diabetes (2020) (9)
- Perioperative Management of Oral Glucose-lowering Drugs in the Patient with Type 2 Diabetes. (2020) (8)
- Physical activity enhances the improvement of body mass index and metabolism by inulin: a multicenter randomized placebo-controlled trial performed in obese individuals (2022) (8)
- OGTT is recommended for glucose homeostasis assessments in Friedreich ataxia (2018) (7)
- The Role of Beta Cell Recovery in Type 2 Diabetes Remission (2022) (7)
- Protein misfolding in combination with other risk factors in CEL-HYB1-mediated chronic pancreatitis. (2020) (6)
- INNODIA Master Protocol for the evaluation of investigational medicinal products in children, adolescents and adults with newly diagnosed type 1 diabetes (2022) (5)
- Pro-Inflammatory Cytokines Induce Insulin and Glucagon Double Positive Human Islet Cells That Are Resistant to Apoptosis (2021) (5)
- Mining genes in type 2 diabetic islets and finding gold. (2012) (4)
- In depth functional characterization of human induced pluripotent stem cell-derived beta cells in vitro and in vivo (2022) (4)
- Effectiveness of Whole-Body High-Intensity Interval Training on Health-Related Fitness: A Systematic Review and Meta-Analysis (2022) (4)
- Modulating the Biomechanical Properties of Engineered Connective Tissues by Chitosan-Coated Multiwall Carbon Nanotubes (2021) (3)
- Sphingolipid subtypes differentially control proinsulin processing and systemic glucose homeostasis (2022) (3)
- Functional genomic analysis of frataxin deficiency reveals tissue-specific alterations and identifies the PPARg pathway as a therapeutic target in Friedreich’s ataxia (2009) (3)
- Europe has to step up its efforts to produce innovative and safe diabetes technology (2017) (3)
- A functional genomic approach to identify reference genes for human pancreatic beta cell real-time quantitative RT-PCR analysis (2021) (3)
- Exercise as a non-pharmacological intervention to protect pancreatic beta cells in individuals with type 1 and type 2 diabetes (2022) (3)
- Microbiota and Metabolite Profiling as Markers of Mood Disorders: A Cross-Sectional Study in Obese Patients (2021) (3)
- Implication of the gut microbiota in personalized metabolic response to dietary inulin in obese patients (2018) (2)
- Epigenetic aspects of pancreatic beta cell function in type 2 diabetes (2014) (2)
- A recombination allele of the lipase gene CEL and its pseudogene CELP encodes a hybrid protein and is a genetic risk factor for chronic pancreatitis (2014) (2)
- The endocrine pancreas: Endoplasmic reticulum stress in the beta cell (2018) (2)
- Pancreatic beta-cell tRNA hypomethylation and fragmentation link TRMT 10 A deficiency with diabetes (2)
- Heterozygous RFX6 protein truncating variants are associated with Maturity-Onset Diabetes of the Young (MODY) with reduced penetrance (2017) (2)
- The Protective Action of Metformin against Pro-Inflammatory Cytokine-Induced Human Islet Cell Damage and the Mechanisms Involved (2022) (2)
- SUN-PO285: Implication of the Gut Microbiota in Personalized Metabolic Response to Dietary Inulin in Obese Patients (2018) (2)
- A Comparative Evaluation of Two Scales Used in the Assessment of Adult Attention Deficit Hyperactivity Disorder (2011) (2)
- Erratum to: Palmitate induces a pro-inflammatory response in human pancreatic islets that mimics CCL2 expression by beta cells in type 2 diabetes (2011) (2)
- Fecal metabolites reflecting the interaction between prebiotic dietary fiber and the gut microbiota in obese patients (2020) (2)
- MCPIP1 is a novel link between diabetogenic conditions and impaired insulin secretory capacity. (2021) (2)
- High fat feeding exacerbates endoplasmic reticulum stress and beta cell demise (2012) (1)
- Dietary inulin supplementation promotes weight loss in obese individuals (2017) (1)
- Future Perspectives for the Treatment of Diabetes: Importance of a Regulatory Framework (2019) (1)
- GLP-1R agonists demonstrate potential to treat Wolfram syndrome in human preclinical models. (2023) (1)
- New players in the beta cell ER stress response: UFM1 and UFBP1 (2010) (1)
- Using different geometries to modulate the cardiac fibroblast phenotype and the biomechanical properties of engineered connective tissues. (2022) (1)
- Modulating the Biomechanical Properties of Engineered Connective Tissues by Chitosan-Coated Multiwall Carbon Nanotubes [Corrigendum] (2021) (1)
- Predicting the Key Regulators of Cell Identity in Human Adult Pancreas (2020) (1)
- Fibroblast Derived Human Engineered Connective Tissue for Screening Applications. (2021) (1)
- A single-cell human islet interactome atlas identifies disrupted autocrine and paracrine communications in type 2 diabetes (2022) (1)
- Study of beta cells and neurons indicate incretin analogs as potential therapeutics for Friedreich’s ataxia. (S32.005) (2015) (1)
- Loss-of-function of the tRNA methyltransferase homolog gene TRMT10A causes young onset diabetes and primary microcephaly in humans (2013) (1)
- Discovery of the gut microbial signature driving the efficacy of prebiotic intervention on liver steatosis (2020) (1)
- Clinical management guidelines for Friedreich ataxia: best practice in rare diseases (2022) (1)
- Mining the transcriptome of target tissues of autoimmune and degenerative pancreatic β-cell and brain diseases to discover therapies (2022) (1)
- LE CALCUL PRATIQUE DES FLECHES DES ELEMENTS HYPERSTATIQUES EN BETON ARME (SUITE) (1977) (1)
- Insulinoma Localization by Glucagon-Like Peptide-1 Receptor Imaging After 18 Years of Hypoglycemia (2015) (1)
- The increased chemokine and cytokine expression by human islets in type 2 diabetes is mimicked by in vitro human islet exposure to palmitate (2008) (1)
- Modulation of adiponectin receptors AdipoR1 and AdipoR2 by phage display-derived peptides in in vitro and in vivo models (2019) (1)
- 1900-P: HNF1A Deficiency Leads to Perturbed Glucagon Secretion in Humans (2020) (1)
- Deletion of C/EBP homologous protein Chop dissociates obesity from insulin resistance (2012) (1)
- Thrombospondin 1 : a master regulator of the anti-oxidant defence in pancreatic beta cells (2015) (0)
- The type 1 diabetes-associated lncRNA ARGI participates in virus-induced pancreatic β cell inflammation (2022) (0)
- PRACTICAL CALCULATION OF THE DEFLECTIONS OF STATICALLY INDETERMINATE REINFORCED CONCRETE MEMBERS (1977) (0)
- Microbiome and metabolome-related biomarkers of mood alterations in obese patients (2021) (0)
- Recovery of human type 2 diabetes beta cell function associates with transcriptomic signatures that point to novel therapeutic targets (2021) (0)
- Effects of insulin on chemoreflex sensitivity (2004) (0)
- Palmitate-induced lipotoxicity alters acetylation of multiple proteins in clonal β cells and human pancreatic islets (2017) (0)
- Single-base deletions in the last exon of the carboxyl ester lipase gene (CEL): Effects on protein misfolding and ER-stress (2019) (0)
- The concurrent deposition of intra-abdominal and subcutaneous fat explains the association between insulin resistance and plasma leptin concentrations in nonobese subjects (2002) (0)
- Combined transcriptome and proteome profiling of the pancreatic β-cell response to palmitate unveils key pathways of β-cell lipotoxicity (2020) (0)
- EFFECTS OF INSULIN ON CHEMOREFLEX SENSITIVITY: P 026 (2004) (0)
- Pirfenidone affects human cardiac fibroblast proliferation and cell cycle activity in 2D cultures and engineered connective tissues. (2023) (0)
- 360-OR: A Novel Genetic Syndrome of Early-Onset Diabetes, Microcephaly, and Epilepsy Due to Homozygous YIPF5 Mutations (2019) (0)
- GLP-1 analogs prevent and revert diabetes in Wolfram syndrome (2019) (0)
- Krüppel-like factor 15 expression dynamics with CRISPR-based gene activation controls cardiomyocyte remodeling in the failing heart (2022) (0)
- Acknowledgement to the Reviewers (2014) (0)
- Free Fatty Acids and Cytokines Induce Pancreatic (cid:1) -Cell Apoptosis by Different Mechanisms: Role of Nuclear Factor- (cid:2) B and Endoplasmic Reticulum Stress (2004) (0)
- Correction to ‘Integration of single-cell datasets reveals novel transcriptomic signatures of β-cells in human type 2 diabetes’ (2021) (0)
- A long non-coding RNA that harbors a SNP associated with type 2 diabetes regulates the expression of TGM2 gene in pancreatic beta cells (2023) (0)
- tRNAGln fragmentation in patient iPSC-derived beta-like cells mediates apoptosis in TRMT10A diabetes (2018) (0)
- {beta}-Cell Dysfunction Transient Oxidative Stress Damages Mitochondrial Machinery Inducing Persistent (2010) (0)
- Pro-inflammatory cytokines induce cell death, inflammatory responses, and endoplasmic reticulum stress in human iPSC-derived beta cells (2020) (0)
- Molecular pathways underlying beta-cell loss in vitro models of type 2 diabetes mellitus (2006) (0)
- University of Dundee Pancreatic-cell tRNA hypomethylation and fragmentation link TRMT 10 A deficiency with diabetes (2018) (0)
- RedRibbon: A new rank-rank hypergeometric overlap pipeline to compare gene and transcript expression signatures (2022) (0)
- tRNAGln derived fragments mediate pancreatic β-cell dysfunction and apoptosis in TRMT10A diabetes. (2018) (0)
- 2090-P: Noradrenergic Stimulus as a Potential Inducer of Human ß-Cell Dedifferentiation (2020) (0)
- Sex Difference in Metabolic Abnormalities in Offspring Born to Diabetic Mothers and Fathers (2009) (0)
- Insulin and chemoreceptors sensitivity (2004) (0)
- Women in Metabolism: Part 3. (2015) (0)
- Long lifespan and very low neogenesis and proliferation of human islet beta cells estimated by mathematical modelling of beta cell lipofuscin accumulation (2008) (0)
- Low Density Lipoprotein Binding and Uptake by Human and Rat Islet (cid:98) Cells* (1997) (0)
- GLP-1 analogs protect beta cells in models of Wolfram syndrome (2018) (0)
- The eukaryotic translation initiation factor 2, a hero turned villain in β cells (2017) (0)
- Inhibition of the type 1 diabetes candidate gene PTPN2 aggravates TNF-α-induced human beta cell dysfunction and death. (2023) (0)
- 2087-P: Functional Genomics of Human Islet Gluco/Lipotoxicity and Type 2 Diabetes (2020) (0)
- Lipotoxic endoplasmic reticulum stress and pancreatic beta cell demise in type 2 diabetes (2012) (0)
- Heterozygous RFX6 protein truncating variants are associated with MODY with reduced penetrance (2017) (0)
- Deletion of C/EBP homologous protein Chop induces abdominal obesity and dissociates obesity from insulin resistance by suppression of inflammation (2012) (0)
- Miss beta cell (2015) (0)
- Enhanced Signaling Downstream of Ribonucleic Acid-Dependent Protein Kinase-Like Kinase Potentiates Lipotoxic Endoplasmic Reticulum Stress in Human Islets (2010) (0)
- Persistent or Transient Human β-Cell Dysfunction Induced by Metabolic Stress Associates with Specific Signatures and Shared Gene Expression of Type 2 Diabetes (2020) (0)
- Supplementary Figure 2 (2013) (0)
- 1031 NON OBESE, NON DIABETIC PATIENTS PRESENTING WITH NON ALCOHOLIC FATTY LIVER DISEASE: AN EXPANDABLE CLINICO-PATHOLOGICAL ENTITY (2009) (0)
- MON-P259: Interest Of Profiling the GUT Microbiota to Evaluate the Effect of Dietary Inulin on Obesity-Related Metabolic Disorders in Humans: The Food4gut Intervention Study (2017) (0)
- Perioperative Management of Glucose-lowering Drugs: Reply. (2020) (0)
- Mechanisms of [beta] cell failure in type 2 diabetes (2013) (0)
- The transcriptome of persistent or transient human beta cell dys- function caused by lipo-glucotoxicity correlates with the gene expres- sion signature of type 2 diabetic islets (2019) (0)
- Treatment of retroperitoneal fibrosis with tamoxifen. (1998) (0)
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