Mitchell Kronenberg | Academic Influence

Mitchell Kronenberg's AcademicInfluence.com Rankings

Mitchell Kronenberg

Biology

#5063

World Rank

#7453

Historical Rank

#1803

USA Rank

Immunology

#228

World Rank

#237

Historical Rank

#61

USA Rank

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Biology

Mitchell Kronenberg's Degrees

PhD Immunology University of California, San Diego
Bachelors Biology University of California, San Diego

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Why Is Mitchell Kronenberg Influential?

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According to Wikipedia, Mitchell Kronenberg is an American immunologist and the chief scientific officer at La Jolla Institute for Immunology. He served as president of the institute from 2003 to 2021. Education Kronenberg received his Bachelor of Science degree from Columbia University in 1973 and a Ph.D. from the California Institute of Technology, where he stayed on to complete postdoctoral work in the laboratory of Leroy Hood.

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Mitchell Kronenberg's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Reciprocal TH17 and Regulatory T Cell Differentiation Mediated by Retinoic Acid (2007) (1991)
NKT cells: what's in a name? (2004) (1201)
Toward an understanding of NKT cell biology: progress and paradoxes. (2005) (1094)
Tracking the Response of Natural Killer T Cells to a Glycolipid Antigen Using Cd1d Tetramers (2000) (967)
Recognition of bacterial glycosphingolipids by natural killer T cells (2005) (946)
Going both ways: immune regulation via CD1d-dependent NKT cells. (2004) (894)
Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis (2009) (833)
The unconventional lifestyle of NKT cells (2002) (805)
CD1-restricted T cell recognition of microbial lipoglycan antigens. (1995) (795)
Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity (2003) (745)
The molecular genetics of the T-cell antigen receptor and T-cell antigen recognition. (1986) (729)
CD1d-mediated Recognition of an α-Galactosylceramide by Natural Killer T Cells Is Highly Conserved through Mammalian Evolution (1998) (683)
Constitutive Cytokine mRNAs Mark Natural Killer (NK) and NK T Cells Poised for Rapid Effector Function (2003) (669)
Activation of natural killer T cells by α-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes (2001) (668)
Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria (2006) (640)
Intravascular Immune Surveillance by CXCR6+ NKT Cells Patrolling Liver Sinusoids (2005) (621)
The natural killer T-cell ligand α-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice (2001) (566)
Specific Inhibition of Cyclooxygenase 2 Restores Antitumor Reactivity by Altering the Balance of IL-10 and IL-12 Synthesis1 (2000) (527)
Prolonged IFN-γ–producing NKT response induced with α-galactosylceramide–loaded DCs (2002) (480)
The unique role of natural killer T cells in the response to microorganisms (2007) (456)
NKT cells derive from double-positive thymocytes that are positively selected by CD1d (2001) (444)
CD4+ invariant T-cell-receptor+ natural killer T cells in bronchial asthma. (2006) (442)
CD1-restricted CD4+ T cells in major histocompatibility complex class II-deficient mice (1995) (413)
Impact of Genetic Polymorphisms on Human Immune Cell Gene Expression (2018) (412)
Selective Ability of Mouse CD1 to Present Glycolipids: α-Galactosylceramide Specifically Stimulates Vα14+ NK T Lymphocytes (1998) (411)
T cell antigen receptors and the immunoglobulin supergene family (1985) (407)
Cutting edge: activation of NK T cells by CD1d and alpha-galactosylceramide directs conventional T cells to the acquisition of a Th2 phenotype. (1999) (390)
Decline in CD28+ T cells in centenarians and in long-term T cell cultures: A possible cause for both in vivo and in vitro immunosenescence (1994) (380)
Mouse T cell antigen receptor: Structure and organization of constant and joining gene segments encoding the β polypeptide (1984) (378)
Regulatory B cells prevent and reverse allergic airway inflammation via FoxP3-positive T regulatory cells in a murine model. (2010) (371)
The mannose receptor delivers lipoglycan antigens to endosomes for presentation to T cells by CD1b molecules. (1997) (361)
Human NKT Cells Mediate Antitumor Cytotoxicity Directly by Recognizing Target Cell CD1d with Bound Ligand or Indirectly by Producing IL-2 to Activate NK Cells1 (2001) (353)
Immunization with α‐galactosylceramide polarizes CD1‐reactive NK T cells towards Th2 cytokine synthesis (1999) (351)
Cutting Edge: Invariant Vα14 NKT Cells Are Required for Allergen-Induced Airway Inflammation and Hyperreactivity in an Experimental Asthma Model1 (2003) (351)
Analysis of intestinal lymphocytes in mouse colitis mediated by transfer of CD4+, CD45RBhigh T cells to SCID recipients. (1997) (349)
Schistosoma mansoni antigens modulate the activity of the innate immune response and prevent onset of type 1 diabetes (2003) (333)
Regulation of immunity by self-reactive T cells (2005) (330)
Natural Killer T Cell Ligand α-Galactosylceramide Enhances Protective Immunity Induced by Malaria Vaccines (2002) (328)
Activation of Natural Killer T Cells Potentiates or Prevents Experimental Autoimmune Encephalomyelitis (2001) (319)
Glycolipid Antigen Drives Rapid Expansion and Sustained Cytokine Production by NK T Cells 1 (2003) (318)
Glycolipid antigen processing for presentation by CD1d molecules. (2001) (305)
Invariant NKT Cells Amplify the Innate Immune Response to Lipopolysaccharide1 (2007) (301)
RAGE, carboxylated glycans and S100A8/A9 play essential roles in colitis-associated carcinogenesis (2008) (299)
Altered Immune Responses in Interleukin 10 Transgenic Mice (1997) (298)
Transcriptional Reprogramming of Mature CD4+ T helper Cells generates distinct MHC class II-restricted Cytotoxic T Lymphocytes (2013) (291)
Cross-presentation of Disialoganglioside GD3 to Natural Killer T Cells (2003) (289)
Mouse CD1 is mainly expressed on hemopoietic-derived cells. (1997) (263)
Peptide binding and presentation by mouse CD1. (1995) (261)
Mouse Vα14i natural killer T cells are resistant to cytokine polarization in vivo (2003) (261)
T cell-derived IL-10 promotes lung cancer growth by suppressing both T cell and APC function. (1999) (259)
The structure, rearrangement and expression of Dβ gene segments of the murine T-cell antigen receptor (1984) (259)
Homeostasis of Vα14i NKT cells (2002) (256)
Bacterial glycolipids and analogs as antigens for CD1d-restricted NKT cells. (2005) (253)
T Cell Responses Modulated Through Interaction Between CD8αα and the Nonclassical MHC Class I Molecule, TL (2001) (250)
The Immune Epitope Database and Analysis Resource: From Vision to Blueprint (2005) (246)
Prolonged IFN-gamma-producing NKT response induced with alpha-galactosylceramide-loaded DCs. (2002) (242)
Anti-Mitochondrial Antibodies and Primary Biliary Cirrhosis in TGF-β Receptor II Dominant-Negative Mice1 (2006) (240)
Glycolipid activation of invariant T cell receptor+ NK T cells is sufficient to induce airway hyperreactivity independent of conventional CD4+ T cells. (2006) (227)
Innate-like functions of natural killer T cell subsets result from highly divergent gene programs (2016) (225)
Quantitation and phenotypic analysis of natural killer T cells in primary biliary cirrhosis using a human CD1d tetramer. (2002) (215)
IL-10-producing NKT10 cells are a distinct regulatory invariant NKT cell subset. (2014) (206)
The identification of the endogenous ligands of natural killer T cells reveals the presence of mammalian α-linked glycosylceramides. (2014) (201)
Retinoic acid can directly promote TGF-beta-mediated Foxp3(+) Treg cell conversion of naive T cells. (2009) (198)
Constitutive Expression of LIGHT on T Cells Leads to Lymphocyte Activation, Inflammation, and Tissue Destruction1 2 (2001) (197)
Production of α-Galactosylceramide by a Prominent Member of the Human Gut Microbiota (2013) (197)
Mesenteric B cells centrally inhibit CD4+ T cell colitis through interaction with regulatory T cell subsets. (2005) (195)
Intestinal microbes affect phenotypes and functions of invariant natural killer T cells in mice. (2012) (192)
Precursors of Functional MHC Class I- or Class II-Restricted CD8αα+ T Cells Are Positively Selected in the Thymus by Agonist Self-Peptides (2002) (187)
Tissue-specific functions of invariant natural killer T cells (2018) (187)
Molecular interaction of CD1b with lipoglycan antigens. (1998) (186)
Cutaneous Immunization Rapidly Activates Liver Invariant Vα14 NKT Cells Stimulating B-1 B Cells to Initiate T Cell Recruitment for Elicitation of Contact Sensitivity (2003) (184)
The natural killer T-cell ligand alpha-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice. (2001) (184)
Disruption of T helper 2-immune responses in Epstein–Barr virus-induced gene 3-deficient mice (2002) (183)
The T cell receptor β chain genes are located on chromosome 6 in mice and chromosome 7 in humans (1984) (181)
CD4+ CD25+ T cells responding to serologically defined autoantigens suppress antitumor immune responses (2003) (178)
Cutting Edge: The Mechanism of Invariant NKT Cell Responses to Viral Danger Signals1 (2008) (177)
Regional specialization of the mucosal immune system. Intraepithelial lymphocytes of the large intestine have a different phenotype and function than those of the small intestine. (1993) (172)
Mouse CD1-autoreactive T cells have diverse patterns of reactivity to CD1+ targets. (1998) (172)
Activation of natural killer T cells in NZB/W mice induces Th1-type immune responses exacerbating lupus. (2003) (170)
Expression of the thymus leukemia antigen in mouse intestinal epithelium. (1990) (169)
Binding and Antigen Presentation of Ceramide-Containing Glycolipids by Soluble Mouse and Human Cd1d Molecules (1999) (168)
Invariant NKT cells recognize glycolipids from pathogenic Gram-positive bacteria (2011) (168)
Unconventional ligand activation of herpesvirus entry mediator signals cell survival (2009) (167)
CD1 expression defines subsets of follicular and marginal zone B cells in the spleen: beta 2-microglobulin-dependent and independent forms. (1998) (165)
CD1d-expressing Dendritic Cells but Not Thymic Epithelial Cells Can Mediate Negative Selection of NKT Cells (2003) (162)
Microsomal triglyceride transfer protein lipidation and control of CD1d on antigen-presenting cells (2005) (158)
Structural requirements for galactosylceramide recognition by CD1-restricted NK T cells. (1998) (154)
The αβ T Cell Response to Self-Glycolipids Shows a Novel Mechanism of CD1b Loading and a Requirement for Complex Oligosaccharides (2000) (151)
Rearrangement and transcription of the β-chain genes of the T-cell antigen receptor in different types of murine lymphocytes (1985) (150)
Rearrangement and expression of T cell antigen receptor and gamma genes during thymic development (1986) (149)
Isolation and characterization of human defensin cDNA clones. (1988) (144)
Natural killer T cells: natural or unnatural regulators of autoimmunity? (2003) (143)
Design of natural killer T cell activators: structure and function of a microbial glycosphingolipid bound to mouse CD1d. (2006) (138)
RNA transcripts for I-J polypeptides are apparently not encoded between the I-A and I-E subregions of the murine major histocompatibility complex. (1983) (137)
Cutting Edge: CD4+CD25+ Regulatory T Cells Impaired for Intestinal Homing Can Prevent Colitis12 (2005) (137)
Failed self-tolerance and autoimmunity in IgG anti-DNA transgenic mice. (1992) (134)
NIK-dependent RelB Activation Defines a Unique Signaling Pathway for the Development of Vα14i NKT Cells (2003) (133)
Hepatic Stellate Cells Function as Regulatory Bystanders (2011) (133)
A crucial role for HVEM and BTLA in preventing intestinal inflammation (2008) (132)
Selective ability of mouse CD1 to present glycolipids: alpha-galactosylceramide specifically stimulates V alpha 14+ NK T lymphocytes. (1998) (129)
Antigen-Specific Cytotoxicity by Invariant NKT Cells In Vivo Is CD95/CD178-Dependent and Is Correlated with Antigenic Potency (2010) (126)
Intestinal intraepithelial lymphocytes are activated and cytolytic but do not proliferate as well as other T cells in response to mitogenic signals. (1993) (124)
Commensal Microbiota and CD8+ T Cells Shape the Formation of Invariant NKT Cells (2009) (123)
The Adaptor Protein AP-3 Is Required for CD1d-Mediated Antigen Presentation of Glycosphingolipids and Development of Vα14i NKT Cells (2003) (123)
The Vα14 NKT Cell TCR Exhibits High-Affinity Binding to a Glycolipid/CD1d Complex1 (2002) (121)
Homeostasis of V alpha 14i NKT cells. (2002) (120)
Mechanisms for Glycolipid Antigen-Driven Cytokine Polarization by Vα14i NKT Cells (2009) (118)
Mouse TCRαβ+CD8αα Intraepithelial Lymphocytes Express Genes That Down-Regulate Their Antigen Reactivity and Suppress Immune Responses12 (2007) (115)
T Cell Intrinsic Heterodimeric Complexes between HVEM and BTLA Determine Receptivity to the Surrounding Microenvironment1 (2009) (115)
Invariant NKT cells are required for airway inflammation induced by environmental antigens (2011) (113)
TSC1 regulates the balance between effector and regulatory T cells. (2013) (113)
Natural killer T cells reactive to a single glycolipid exhibit a highly diverse T cell receptor β repertoire and small clone size (2001) (112)
The design and implementation of the immune epitope database and analysis resource (2005) (111)
HVEM signalling at mucosal barriers provides host defence against pathogenic bacteria (2012) (110)
The Crohn's disease-associated bacterial protein I2 is a novel enteric t cell superantigen. (2001) (108)
Protein Kinase C-η Controls CTLA-4-Mediated Regulatory T Cell Function (2014) (107)
Mouse V alpha 14i natural killer T cells are resistant to cytokine polarization in vivo. (2003) (107)
Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis (2018) (104)
Lipid binding orientation within CD1d affects recognition of Borrelia burgorferi antigens by NKT cells (2009) (101)
The T cell antigen receptor expressed by Valpha14i NKT cells has a unique mode of glycosphingolipid antigen recognition. (2004) (101)
NKT cells prevent chronic joint inflammation after infection with Borrelia burgdorferi (2008) (100)
CD1-mediated immune responses to glycolipids. (1999) (96)
CD1 tetramers: a powerful tool for the analysis of glycolipid-reactive T cells. (2002) (94)
IL-10 producing intestinal macrophages prevent excessive anti-bacterial innate immunity by limiting IL-23 synthesis (2015) (93)
Cutting edge: anti-CD1 monoclonal antibody treatment reverses the production patterns of TGF-beta 2 and Th1 cytokines and ameliorates listeriosis in mice. (1999) (92)
Targeted delivery of lipid antigen to macrophages via the CD169/sialoadhesin endocytic pathway induces robust invariant natural killer T cell activation (2013) (92)
Natural killer T cells exacerbate liver injury in a transforming growth factor β receptor II dominant‐negative mouse model of primary biliary cirrhosis (2007) (91)
Structural requirements for antigen presentation by mouse CD1. (2000) (91)
The Crystal Structure of a TL/CD8αα Complex at 2.1 Å Resolution: Implications for Modulation of T Cell Activation and Memory (2003) (90)
T cell responses modulated through interaction between CD8alphaalpha and the nonclassical MHC class I molecule, TL. (2001) (88)
Antigen-Dependent versus -Independent Activation of Invariant NKT Cells during Infection (2014) (87)
Activation and Function of iNKT and MAIT Cells. (2015) (85)
The Vα14 invariant natural killer T cell TCR forces microbial glycolipids and CD1d into a conserved binding mode (2010) (85)
The neutrotime transcriptional signature defines a single continuum of neutrophils across biological compartments (2021) (83)
Crystal Structure of Mouse CD1d Bound to the Self Ligand Phosphatidylcholine: A Molecular Basis for NKT Cell Activation12 (2005) (83)
Precursors of functional MHC class I- or class II-restricted CD8alphaalpha(+) T cells are positively selected in the thymus by agonist self-peptides. (2002) (82)
Cutting Edge: Activation by Innate Cytokines or Microbial Antigens Can Cause Arrest of Natural Killer T Cell Patrolling of Liver Sinusoids1 (2008) (82)
Assignment of defensin gene(s) to human chromosome 8p23. (1989) (81)
Regulation of inflammation, autoimmunity, and infection immunity by HVEM‐BTLA signaling (2011) (81)
Lack of Chemokine Receptor CCR5 Promotes Murine Fulminant Liver Failure by Preventing the Apoptosis of Activated CD1d-Restricted NKT Cells1 (2005) (80)
Unique Lamina Propria Stromal Cells Imprint the Functional Phenotype of Mucosal Dendritic Cells (2014) (80)
An Opposite Pattern of Selection of a Single T Cell Antigen Receptor in the Thymus and among Intraepithelial Lymphocytes (1998) (77)
Transcriptional regulator Id2 controls survival of hepatic NKT cells (2009) (76)
Gene rearrangement in cells with natural killer activity and expression of the β-chain of the T-cell antigen receptor (1985) (76)
Synthesis and evaluation of sphinganine analogues of KRN7000 and OCH. (2005) (76)
Exosome-like Nanoparticles from Intestinal Mucosal Cells Carry Prostaglandin E2 and Suppress Activation of Liver NKT Cells (2013) (75)
Activation or anergy: NKT cells are stunned by α-galactosylceramide (2005) (75)
Nonclassical behavior of the thymus leukemia antigen: peptide transporter-independent expression of a nonclassical class I molecule (1995) (75)
Mouse TCRalphabeta+CD8alphaalpha intraepithelial lymphocytes express genes that down-regulate their antigen reactivity and suppress immune responses. (2007) (74)
Innate-like recognition of microbes by invariant natural killer T cells. (2009) (74)
Activation of Invariant NKT Cells Ameliorates Experimental Ocular Autoimmunity by A Mechanism Involving Innate IFN-γ Production and Dampening of the Adaptive Th1 and Th17 Responses1 (2008) (74)
Cutting Edge: TCRαβ+ CD8αα+ T Cells Are Found in Intestinal Intraepithelial Lymphocytes of Mice That Lack Classical MHC Class I Molecules (1999) (74)
Vα14i NKT Cells Are Innate Lymphocytes That Participate in the Immune Response to Diverse Microbes (2005) (73)
Membrane Lymphotoxin Is Required for the Development of Different Subpopulations of NK T Cells1 2 (2000) (72)
Mechanisms of NKT cell anergy induction involve Cbl-b-promoted monoubiquitination of CARMA1 (2009) (72)
Regulatory T-cell stability and plasticity in mucosal and systemic immune systems (2010) (72)
Helper and killer T cells do not express B cell immunoglobulin joining and constant region gene segments (1980) (71)
Loss of T Cell and B Cell Quiescence Precedes the Onset of Microbial Flora-Dependent Wasting Disease and Intestinal Inflammation in Gimap5-Deficient Mice (2010) (71)
An Anti-Inflammatory Role for Vα14 NK T cells in Mycobacterium bovis Bacillus Calmette-Guérin-Infected Mice1 (2003) (70)
Distinct Requirements for Activation of NKT and NK Cells during Viral Infection (2014) (68)
Expansion of human Vα24+ NKT cells by repeated stimulation with KRN7000 (2004) (68)
Nonclassical behavior of the mouse CD1 class I-like molecule. (1997) (68)
Regulation of mucosal immune responses by recombinant interleukin 10 produced by intestinal epithelial cells in mice. (2002) (67)
The alphabeta T cell response to self-glycolipids shows a novel mechanism of CD1b loading and a requirement for complex oligosaccharides. (2000) (66)
The Mouse CD1d Cytoplasmic Tail Mediates CD1d Trafficking and Antigen Presentation by Adaptor Protein 3-Dependent and -Independent Mechanisms1 (2005) (66)
On the road: progress in finding the unique pathway of invariant NKT cell differentiation. (2007) (66)
Intrathymic NKT cell development is blocked by the presence of α‐galactosylceramide (2003) (66)
TAP-independent selection of CD8+ intestinal intraepithelial lymphocytes. (1996) (64)
Thymic differentiation of TCRαβ+ CD8αα+ IELs (2007) (64)
Natural Sphingomonas glycolipids vary greatly in their ability to activate natural killer T cells. (2008) (64)
Presentation of self and microbial lipids by CD1 molecules. (2001) (63)
Diverse Endogenous Antigens for Mouse NKT Cells: Self-Antigens That Are Not Glycosphingolipids (2011) (63)
Mouse T lymphocytes that express a gamma delta T-cell antigen receptor contribute to resistance to Salmonella infection in vivo (1994) (63)
The V alpha 14 NKT cell TCR exhibits high-affinity binding to a glycolipid/CD1d complex. (2002) (62)
CD1 mediated T cell recognition of glycolipids. (2007) (61)
Systemic NKT cell deficiency in NOD mice is not detected in peripheral blood: implications for human studies (2004) (61)
Highly conserved antigen-presenting function of CD1d molecules (1999) (60)
Co-receptor choice by Vα14i NKT cells is driven by Th-POK expression rather than avoidance of CD8-mediated negative selection (2010) (58)
The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in Lymphomagenesis (2019) (58)
αβT cell receptors expressed by CD4(-)CD8αβ(-) intraepithelial T cells drive their fate into a unique lineage with unusual MHC reactivities. (2014) (58)
IFN-γ-mediated negative feedback regulation of NKT cell function by CD94/NKG2 (2005) (58)
Antigens recognized by gamma delta T cells. (1994) (57)
Role of NKT cells in the digestive system. IV. The role of canonical natural killer T cells in mucosal immunity and inflammation. (2008) (56)
II. The yin and yang of T cells in intestinal inflammation: pathogenic and protective roles in a mouse colitis model. (1999) (56)
Invariant NKT Cells Require Autophagy To Coordinate Proliferation and Survival Signals during Differentiation (2015) (56)
Natural killer T cells exacerbate liver injury in a transforming growth factor beta receptor II dominant-negative mouse model of primary biliary cirrhosis. (2008) (56)
The transcription factor Th-POK negatively regulates Th17 differentiation in Vα14i NKT cells. (2012) (55)
Helicobacter pylori Cholesteryl α-Glucosides Contribute to Its Pathogenicity and Immune Response by Natural Killer T Cells (2013) (55)
The role of invariant natural killer T cells in microbial immunity (2013) (55)
Selection of T lymphocytes bearing limited T-cell receptor beta chains in the response to a human pathogen. (1993) (54)
Salmonella typhimurium infection halts development of type 1 diabetes in NOD mice (2004) (54)
Interleukin-27 Receptor Limits Atherosclerosis in Ldlr−/− Mice (2012) (53)
A Novel Role for IL-27 in Mediating the Survival of Activated Mouse CD4 T Lymphocytes (2013) (52)
β7 Integrin expression is not required for the localization of T cells to the intestine and colitis pathogenesis (2002) (52)
A new mouse strain for the analysis of invariant NKT cell function (2015) (52)
The Murine Nonclassical Class I Major Histocompatibility Complex–like CD1.1 Molecule Protects Target Cells from Lymphokine-activated Killer Cell Cytolysis (1999) (52)
BTLA Interaction with HVEM Expressed on CD8+ T Cells Promotes Survival and Memory Generation in Response to a Bacterial Infection (2013) (51)
Prevention of experimental autoimmune arthritis with a peptide fragment of type II collagen (1993) (51)
Three T cell hybridomas do not contain detectable heavy chain variable gene transcripts (1983) (51)
Surface receptors identify mouse NK1.1+ T cell subsets distinguished by function and T cell receptor type (2004) (50)
Activation of natural killer T cells by glycolipids. (2006) (50)
Syntheses of biotinylated alpha-galactosylceramides and their effects on the immune system and CD1 molecules. (1999) (50)
Escherichia coli infection induces autoimmune cholangitis and anti‐mitochondrial antibodies in non‐obese diabetic (NOD).B6 (Idd10/Idd18) mice (2014) (49)
T and B cells that recognize the same antigen do not transcribe similar heavy chain variable region gene segments (1983) (49)
A CD1d-Dependent Antagonist Inhibits the Activation of Invariant NKT Cells and Prevents Development of Allergen-Induced Airway Hyperreactivity (2010) (49)
Unique Interplay between Sugar and Lipid in Determining the Antigenic Potency of Bacterial Antigens for NKT Cells (2011) (49)
The tumor necrosis factor family member TNFSF14 (LIGHT) is required for resolution of intestinal inflammation in mice. (2014) (48)
Altered thymic differentiation and modulation of arthritis by invariant NKT cells expressing mutant ZAP70 (2018) (48)
Structure and function of H-2 T (Tla) region class I MHC molecules. (1994) (48)
ICOS costimulates invariant NKT cell activation. (2005) (48)
B cells are anergic in transgenic mice that express IgM anti‐DNA antibodies (1993) (47)
Generation of intestinal mucosal lymphocytes in SCID mice reconstituted with mature, thymus-derived T cells. (1998) (46)
Promoter-interacting expression quantitative trait loci are enriched for functional genetic variants (2020) (46)
The structure and genetics of mouse immunoglobulins: an analysis of NZB myeloma proteins and sets of BALB/c myeloma proteins binding particular haptens. (1977) (46)
Mucosal CD8 Memory T Cells are selected in the periphery by an MHC Class I Molecule (2011) (46)
Presentation of peptide antigens by mouse CD1 requires endosomal localization and protein antigen processing. (1998) (45)
Activation or anergy: NKT cells are stunned by alpha-galactosylceramide. (2005) (45)
Fibrocyte-like cells recruited to the spleen support innate and adaptive immune responses to acute injury or infection (2011) (44)
Mucosal immunity and inflammation. II. The yin and yang of T cells in intestinal inflammation: pathogenic and protective roles in a mouse colitis model. (1999) (44)
The Role of Innate Immunity in Autoimmunity (2004) (44)
Intestinal intraepithelial lymphocytes respond to systemic lymphocytic choriomeningitis virus infection. (1996) (44)
The thymus leukemia antigen binds human and mouse CD8 (1991) (44)
Intrathymic NKT cell development is blocked by the presence of alpha-galactosylceramide. (2003) (43)
Molecular biology of NK T cell specificity and development. (2000) (43)
Systemic activation and antigen-driven oligoclonal expansion of T cells in a mouse model of colitis. (2000) (43)
Crucial amino acid residues of mouse CD1d for glycolipid ligand presentation to Vα14 NKT cells (2001) (43)
Synthesis and evaluation of 3''- and 4''-deoxy and -fluoro analogs of the immunostimulatory glycolipid, KRN7000. (2009) (42)
Neutrophilic Granulocytes Modulate Invariant NKT Cell Function in Mice and Humans (2012) (42)
Glycolipids that elicit IFN-γ-biased responses from natural killer T cells. (2011) (42)
Making memory at birth: understanding the differentiation of natural killer T cells. (2012) (42)
The Proatherogenic Role of T Cells Requires Cell Division and Is Dependent on the Stage of the Disease (2005) (42)
REARRANGEMENT AND EXPRESSION OF T CELL ANTIGEN RECEPTOR AND ~' GENES DURING THYMIC DEVELOPMENT (1986) (41)
Organization of the V gene segments in mouse T-cell antigen receptor alpha/delta locus. (1994) (40)
Self-tolerance and autoimmunity (1991) (40)
Carboxylated Glycans Mediate Colitis through Activation of NF-κB1 (2005) (40)
Regulating the mucosal immune system: the contrasting roles of LIGHT, HVEM, and their various partners (2009) (38)
Jarid2 is induced by TCR signalling and controls iNKT cell maturation (2014) (38)
Transgenic Expression of IL-10 in T Cells Facilitates Development of Experimental Myasthenia Gravis1 (2001) (38)
Carbohydrate specificity of the recognition of diverse glycolipids by natural killer T cells (2009) (38)
NKG2A Inhibits Invariant NKT Cell Activation in Hepatic Injury1 (2009) (38)
The crystal structure of a TL/CD8alphaalpha complex at 2.1 A resolution: implications for modulation of T cell activation and memory. (2003) (38)
Expansion of human Valpha24+ NKT cells by repeated stimulation with KRN7000. (2004) (37)
Cutting Edge: IFN-γ Signaling to Macrophages Is Required for Optimal Vα14i NK T/NK Cell Cross-Talk1 (2005) (37)
Development of Asthma in Inner-City Children: Possible Roles of MAIT Cells and Variation in the Home Environment (2018) (36)
Mucosal memory CD 8 + T cells are selected in the periphery by an MHC class I molecule (2011) (35)
Elevated serum anti‐I2 and anti‐OmpW antibody levels in children with IBD (2006) (35)
A unique lymphotoxin {alpha}beta-dependent pathway regulates thymic emigration of V{alpha}14 invariant natural killer T cells. (2006) (35)
Riboflavin Metabolism Variation among Clinical Isolates of Streptococcus pneumoniae Results in Differential Activation of Mucosal‐associated Invariant T Cells (2018) (35)
Thymic differentiation of TCR alpha beta(+) CD8 alpha alpha(+) IELs. (2007) (33)
OMIP‐030: Characterization of human T cell subsets via surface markers (2015) (33)
Human Invariant Vα24-JαQ TCR Supports the Development of CD1d-Dependent NK1.1+ and NK1.1− T Cells in Transgenic Mice 1 (2003) (33)
The Complementarity Determining Region 2 of BV8S2 (Vβ8.2) Contributes to Antigen Recognition by Rat Invariant NKT Cell TCR1 (2006) (33)
IFN-gamma-mediated negative feedback regulation of NKT-cell function by CD94/NKG2. (2005) (33)
Reduced expression of phosphatase PTPN2 promotes pathogenic conversion of Tregs in autoimmunity (2019) (33)
Conserved lipid and peptide presentation functions of nonclassical class I molecules. (1999) (32)
Interruption of CXCL13-CXCR5 Axis Increases Upper Genital Tract Pathology and Activation of NKT Cells following Chlamydial Genital Infection (2012) (32)
Carboxylated glycans mediate colitis through activation of NF-kappa B. (2005) (32)
Systemic Activation and Antigen-Driven Oligoclonal Expansion of T Cells in a Mouse Model of Colitis1 (2000) (31)
Peptide-Independent Folding and CD8αα Binding by the Nonclassical Class I Molecule, Thymic Leukemia Antigen1 (2002) (31)
An automated semiquantitative B and T cell clonality assay. (1999) (30)
Mouse TCRαβ+CD8αα intraepithelial lymphocytes express genes that down-regulate their antigen reactivity and suppress immune responses (2007) (30)
The role of CD1 molecules in immune responses to infection. (1997) (30)
The Third Way: Progress on pathways of antigen processing and presentation by CD1 (2004) (30)
Invariant natural killer T cells: front line fighters in the war against pathogenic microbes (2016) (30)
Interplay between carbohydrate and lipid in recognition of glycolipid antigens by natural killer T cells (2012) (29)
LIGHT-HVEM Signaling in Innate Lymphoid Cell Subsets Protects Against Enteric Bacterial Infection. (2018) (29)
Molecular Basis for the High Affinity Interaction between the Thymic Leukemia Antigen and the CD8αα Molecule1 (2005) (29)
Diversity of Ig V gene segments found in anti-DNA autoantibodies from a single (NZB x NZW)F1 mouse. (1989) (29)
The A′ and F′ Pockets of Human CD1b Are Both Required for Optimal Presentation of Lipid Antigens to T Cells1 (2001) (28)
The role of innate lymphoid cells in response to microbes at mucosal surfaces (2020) (28)
Antigen‐presenting Function of the TL Antigen and Mouse CD1 Molecules (1995) (27)
The transcription factor NR4A3 controls CD103+ dendritic cell migration. (2016) (27)
An Anti-Inflammatory Role for V 14 NK T cells in Mycobacterium bovis Bacillus Calmette-Guérin-Infected Mice (2003) (26)
MHC‐dependent and ‐independent modulation of endogenous Ly49 receptors on NK1.1+ T lymphocytes directed by T‐cell receptor type (2003) (26)
Pivotal Advance: α‐Galactosylceramide induces protection against lipopolysaccharide‐induced shock (2007) (26)
The Tumor Necrosis Factor Superfamily Members TNFSF14 (LIGHT), Lymphotoxin β and Lymphotoxin β Receptor Interact to Regulate Intestinal Inflammation (2018) (26)
A Novel Glycolipid Antigen for NKT Cells That Preferentially Induces IFN-γ Production (2015) (25)
A TNFRSF14-FcɛRI-mast cell pathway contributes to development of multiple features of asthma pathology in mice (2016) (25)
LIGHT–HVEM signaling in keratinocytes controls development of dermatitis (2018) (24)
Abrogation of Anti-Retinal Autoimmunity in IL-10 Transgenic Mice Due to Reduced T Cell Priming and Inhibition of Disease Effector Mechanisms1 (2008) (24)
Autoimmunity-Associated LYP-W620 Does Not Impair Thymic Negative Selection of Autoreactive T Cells (2014) (24)
Phenotypical and functional alterations during the expansion phase of invariant Vα14 natural killer T (Vα14i NKT) cells in mice primed with α‐galactosylceramide (2005) (24)
Transcriptional control of the development and function of Vα14i NKT cells. (2014) (24)
CD1 and MHC II find different means to the same end. (2005) (24)
Cutting edge: TCR alpha beta+ CD8 alpha alpha+ T cells are found in intestinal intraepithelial lymphocytes of mice that lack classical MHC class I molecules. (1999) (24)
The role of invariant NKT cells at the interface of innate and adaptive immunity. (2010) (23)
CD1-mediated antigen presentation of glycosphingolipids. (2000) (23)
Intestinal mucus‐derived nanoparticle–mediated activation of Wnt/β‐catenin signaling plays a role in induction of liver natural killer T cell anergy in mice (2013) (23)
Mapping genomic organization by field inversion and two-dimensional gel electrophoresis: application to the murine T-cell receptor gamma gene family. (1988) (22)
A Sensitive and Integrated Approach to Profile Messenger RNA from Samples with Low Cell Numbers. (2018) (22)
Development of lymphoma in the thymus of AKR mice treated with the lymphomagenic virus SL 3-3. (1989) (22)
Villous B Cells of the Small Intestine Are Specialized for Invariant NK T Cell Dependence1 (2008) (22)
ATP Binding Cassette Transporter ABCA7 Regulates NKT Cell Development and Function by Controlling CD1d Expression and Lipid Raft Content (2017) (22)
CD1d-restricted peripheral T cell lymphoma in mice and humans (2016) (21)
TSC 1 regulates the balance between effector and regulatory T cells (2018) (21)
HVEM is a TNF Receptor with Multiple Regulatory Roles in the Mucosal Immune System (2014) (20)
Natural killer T cells: Know thyself (2007) (20)
Restriction fragment length polymorphisms of the mouse T-cell receptor gene families (2006) (20)
Herpes Simplex Virus 1 Latency and the Kinetics of Reactivation Are Regulated by a Complex Network of Interactions between the Herpesvirus Entry Mediator, Its Ligands (gD, BTLA, LIGHT, and CD160), and the Latency-Associated Transcript (2018) (20)
Antigen specificity of invariant natural killer T-cells (2015) (20)
The alpha 3 domain of the Qa-2 molecule is defective for CD8 binding and cytotoxic T lymphocyte activation (1993) (20)
Selective Conditions Are Required for the Induction of Invariant NKT Cell Hyporesponsiveness by Antigenic Stimulation (2015) (20)
Infection, autoimmunity, and glycolipids: T cells detect microbes through self-recognition. (2005) (19)
Carbohydrate Moieties as Vaccine Candidates: meeting summary. (2010) (19)
When Insult Is Added to Injury: Cross Talk between ILCs and Intestinal Epithelium in IBD (2016) (19)
Elongated neutrophil-derived structures are blood-borne microparticles formed by rolling neutrophils during sepsis (2020) (19)
NKT cells turn ten (2009) (19)
Finding the T-cell antigen receptor: Past attempts and future promise (1983) (18)
CD1d1 Displayed on Cell Size Beads Identifies and Enriches an NK Cell Population Negatively Regulated by CD1d11 (2004) (18)
Murine Corneal Inflammation and Nerve Damage After Infection With HSV-1 Are Promoted by HVEM and Ameliorated by Immune-Modifying Nanoparticle Therapy (2017) (18)
Do mucosal T cells prevent intestinal inflammation? (2000) (18)
HVEM: An unusual TNF receptor family member important for mucosal innate immune responses to microbes. (2013) (18)
Presentation of bacterial lipid antigens by CD1 molecules. (1998) (17)
Improved Detection of Cytokines Produced by Invariant NKT Cells (2017) (17)
Immediate antigen‐specific effector functions byTCR‐transgenic CD8+ NKT cells (2006) (17)
ATP-Binding Cassette Transporter G1 Intrinsically Regulates Invariant NKT Cell Development (2012) (17)
Cutting edge: IFN-gamma signaling to macrophages is required for optimal Valpha14i NK T/NK cell cross-talk. (2005) (17)
Intermittent PI3Kδ inhibition sustains anti-tumour immunity and curbs irAEs (2022) (17)
Frontline T cells: γδ T cells and intraepithelial lymphocytes (2007) (16)
The Roles of 3′ and 4′ Hydroxy Groups in α‐Galactosylceramide Stimulation of Invariant Natural Killer T Cells (2009) (16)
Human invariant V alpha 24-J alpha Q TCR supports the development of CD1d-dependent NK1.1+ and NK1.1- T cells in transgenic mice. (2003) (16)
When Less Is More: T Lymphocyte Populations with Restricted Antigen Receptor Diversity (2014) (16)
Role of MAIT cells in pulmonary bacterial infection. (2018) (15)
Lipid and Carbohydrate Modifications of α-Galactosylceramide Differently Influence Mouse and Human Type I Natural Killer T Cell Activation* (2015) (14)
Self‐Reactive γδ T Lymphocytes: Implications for T‐Cell Ontogeny and Reactivity (1991) (14)
Pivotal advance: alpha-galactosylceramide induces protection against lipopolysaccharide-induced shock. (2007) (14)
A microRNA expression and regulatory element activity atlas of the mouse immune system (2021) (14)
Surprisingly minor influence of TRAV11 (Vα14) polymorphism on NK T-receptor mCD1/α-galactosylceramide binding kinetics (2003) (14)
Phenotypical and functional alterations during the expansion phase of invariant Valpha14 natural killer T (Valpha14i NKT) cells in mice primed with alpha-galactosylceramide. (2005) (14)
The Mechanism of Invariant NKT Cell Responses to Viral Danger Signals (134.8) (2009) (14)
A unique pattern of lymphokine synthesis is a characteristic of certain antigen-specific suppressor T cell clones. (1994) (14)
In vivo activation of invariant Vα14 natural killer T cells by α‐galactosylceramide sequentially induces Fas‐dependent and ‐independent cytotoxicity (2004) (13)
Molecular basis for the high affinity interaction between the thymic leukemia antigen and the CD8alphaalpha molecule. (2005) (13)
Frontline T cells: gammadelta T cells and intraepithelial lymphocytes. (2007) (13)
Colitis-related public T cells are selected in the colonic lamina propria of IL-10-deficient mice. (2002) (13)
Cancer immunity thwarted by the microbiome (2018) (13)
Spontaneous Colitis Occurrence in Transgenic Mice with Altered B7-Mediated Costimulation1 (2008) (13)
NKT10 cells: a novel iNKT cell subset (2015) (13)
Crucial amino acid residues of mouse CD1d for glycolipid ligand presentation to V(alpha)14 NKT cells. (2001) (13)
Mucosal T lymphocytes—peacekeepers and warriors (2005) (13)
Transcriptome and chromatin landscape of iNKT cells are shaped by subset differentiation and antigen exposure (2020) (12)
CD1: clues on a new antigen-presenting pathway. (1996) (12)
Differential Role of Cathepsins S and B In Hepatic APC-Mediated NKT Cell Activation and Cytokine Secretion (2018) (12)
The Protein Phosphatase Shp1 Regulates Invariant NKT Cell Effector Differentiation Independently of TCR and Slam Signaling (2019) (11)
Paradoxical Effect of Reduced Costimulation in T Cell-Mediated Colitis12 (2007) (11)
Expression of mouse Tla region class I genes in tissues enriched for γδ cells (1992) (11)
Expression of mouse Tla region class I genes in tissues enriched for gamma delta cells. (1992) (10)
Mrp1 is involved in lipid presentation and iNKT cell activation by Streptococcus pneumoniae (2018) (10)
HVEM (2013) (9)
Analysis of MHC class I gene expression in adult bone marrow and fetal liver of the BALB/c mouse. (1991) (9)
Peptide-independent folding and CD8 alpha alpha binding by the nonclassical class I molecule, thymic leukemia antigen. (2002) (9)
Immunology: Oiling the wheels of autoimmunity (2014) (9)
Detection of microbes by natural killer T cells. (2009) (9)
Characterization of a CD4-positive T-cell line derived from an athymic (nu/nu) mouse. (1991) (9)
Invariant natural killer T cells are depleted in renal impairment and recover after kidney transplantation. (2014) (9)
Antigen‐presenting Function of the Mouse CD1 Molecule a (1996) (9)
MHC evolution: a long term investment in defense. (1994) (9)
TCR-mediated recognition of glycolipid CD1 complexes. (2007) (9)
The alpha and omega of galactosylceramides in T cell immune function. (2015) (8)
In vivo activation of invariant V alpha 14 natural killer T cells by alpha-galactosylceramide sequentially induces Fas-dependent and -independent cytotoxicity. (2004) (8)
Right on target: Novel approaches for the direct visualization of CD1-specific T cell responses (2001) (8)
A 'GEM' of a cell (2013) (8)
CD 1 Expression Defines Subsets of Follicular and Marginal Zone B Cells in the Spleen : b 2-Microglobulin-Dependent and Independent Forms 1 (1998) (8)
Spontaneous resistance to acute T-cell leukaemias in TCRV gamma 1.1J gamma 4C gamma 4 transgenic mice. (1995) (7)
Restriction fragment length polymorphisms of the mouse T-cell receptor gene families (2004) (7)
Invariant natural killer cells in the response to bacteria: the advent of specific antigens. (2006) (7)
Chapter 30 – Development, Function, and Specificity of Intestinal Intraepithelial Lymphocytes (2005) (7)
T-Cell Receptor γδ Diversity and Specificity of Intestinal Intraepithelial Lymphocytes: Analysis of IEL-Derived Hybridomas (1993) (7)
Depletion of mouse alpha beta T cell antigen receptor bearing lymphocytes by neonatal monoclonal antibody treatment. (1991) (7)
This information is current as Prevent Colitis Cells Impaired for Intestinal Homing Can Regulatory T + CD 25 + Cutting Edge : CD 4 (2005) (7)
Cooling the fires of inflammation (2011) (7)
Lymphocyte—Epithelial Cross-Talk in the Intestine: Do Nonclassical Class I Molecules Have a Big Part in the Dialogue? (1996) (6)
Response to Comment on “Development of Asthma in Inner-City Children: Possible Roles of MAIT Cells and Variation in the Home Environment” (2018) (6)
The Alpha and Omega of Galactosylceramides in T Cell Immune Function* (2015) (6)
Metabolic activation and colitis pathogenesis is prevented by lymphotoxin β receptor expression in neutrophils (2021) (6)
Antibody and MHC genes. (1982) (6)
HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160 (2021) (6)
Synergistic Costimulation by Both B7 Molecules Regulates Colitis Pathogenesis (2006) (6)
A unique lymphotoxin -dependent pathway regulates thymic emigration of V 14 invariant natural killer T cells (2006) (5)
Presenting fats with SAPs (2004) (5)
Therapeutic Blockade of LIGHT Interaction With Herpesvirus Entry Mediator and Lymphotoxin &bgr; Receptor Attenuates In Vivo Cytotoxic Allogeneic Responses (2014) (5)
Database of Immune Cell EQTLs, Expression, Epigenomics (2019) (5)
Synthesis of a 2''-Deoxy-β-GalCer (2014) (5)
Tolerance and Self-Reactivity in Vγ1.1Cγ4 Transgenic Mice (1994) (5)
Surprisingly minor influence of TRAV11 (Valpha14) polymorphism on NK T-receptor mCD1/alpha-galactosylceramide binding kinetics. (2003) (5)
Molecular and serological diversity of anti-DNA autoantibodies from NZB and (NZB × NZW) F1 mice (1988) (5)
Acid test: lipid antigens get into the groove. (2008) (4)
Escherichia coli infection induces autoimmune cholangitis and antimitochondrial antibodies in NOD.B6 (Idd10/Idd18) mice: Clin Exp Immunol - used Patrick's E. Coli 9-9-13.enl. (2013) (4)
39 – Cloned T Cells as a Tool for Molecular Geneticists: Approaches to Cloning Genes Which Encode T Cell Antigen Receptors (1982) (4)
Function APCGrowth by Suppressing Both T Cell and T Cell-Derived IL-10 Promotes Lung Cancer Dubinett (1999) (4)
MHC evolution: a long-term investment in defense (1994) (3)
A method for production of recombinant mCD1d protein in insect cells. (2007) (3)
Tolerance and self-reactivity in V gamma 1.1C gamma 4 transgenic mice. (1994) (3)
IL-27 Receptor Limits Atherosclerosis in Ldlr -/- Mice (2012) (3)
Genes, structures and function of T lymphocyte antigen receptors. (1985) (3)
Lipid-CD1-reactive T cells. (2000) (3)
Modulation of immune responses by targeting CD169/Siglec-1 with the glycan ligand (2011) (3)
The Thymus Leukemia Antigen Binds Human and Mouse CD 8 By (2003) (3)
Characterization of collagen-specific T cells derived from pathogenic and nonpathogenic rat T cell lines. (1990) (3)
Molecular Basis for NKT Cell Activation the Self Ligand Phosphatidylcholine: A Crystal Structure of Mouse CD1d Bound to (2005) (2)
Lymphotoxin beta receptor mediated activation of RelB by NIK defines a unique signaling pathway for the development of V alpha 14i NKT cells (2003) (2)
Recognition by Rat Invariant NKT Cell TCR 8 . 2 ) Contributes to Antigen β of BV 8 S 2 ( V The Complementarity Determining Region 2 Kronenberg and (2006) (2)
Btla signaling in conventional and regulatory lymphocytes coordinately tempers humoral immunity in the intestinal mucosa (2021) (2)
Hypoxia induces adrenomedullin from lung epithelia, stimulating ILC2 inflammation and immunity (2022) (2)
Publisher Correction: Gut CD4+ T cell phenotypes are a continuum molded by microbes, not by TH archetypes (2021) (2)
T-cell receptor gamma delta diversity and specificity of intestinal intraepithelial lymphocytes: analysis of IEL-derived hybridomas. (1993) (2)
IL-27 mediated silencing of Foxp3 gene expression via enhanced DNA methylation (152.26) (2011) (2)
Epithelial HVEM maintains intraepithelial T cell survival and contributes to host protection (2022) (2)
Inflammation, and Tissue Destruction Leads to Lymphocyte Activation, Constitutive Expression of LIGHT on T Cells (2001) (2)
Calcium signals regulate the functional differentiation of thymic iNKT cells (2021) (2)
Promoter-Interacting Expression Quantitative Trait Loci (pieQTLs) in Human Immune Cell Types (2019) (2)
Transcriptomes and metabolism define mouse and human MAIT cell heterogeneity (2021) (2)
by Producing IL-2 to Activate NK Cells Cell CD1d with Bound Ligand or Indirectly Cytotoxicity Directly by Recognizing Target Human NKT Cells Mediate Antitumor (2001) (2)
Crystal structure of mouse CD1d with a phospholipid self ligand: insights in the molecular basis of regulatory NKT cell activation (2004) (2)
Metabolic Triggers of Invariant Natural Killer T-Cell Activation during Sterile Autoinflammatory Disease. (2020) (2)
Program and abstracts for the 2012 Joint Meeting of the Society for Glycobiology & American Society for Matrix Biology (2012) (2)
Interview: glycolipid antigen presentation by CD1d and the therapeutic potential of NKT cell activation. (2007) (2)
The ImmGen consortium OpenSource T cell project (2022) (1)
Immune regulation by CD11b+ myeloid cells in the intestine (P3195) (2013) (1)
Engineered Stem Cells Provide Cancer-Killing iNKT Cells. (2019) (1)
Interleukin 10 acts on regulatory T cells to maintain Foxp3 expression and suppressive function in mice with colitis. (2011) (1)
CD160-HVEM signaling in intestinal epithelial cells modulates gut microbial homeostasis (2019) (1)
Crystal Structure of mouse CD1d bound to the self ligand phosphatidylcholine (2005) (1)
Airway Hyperreactivity Prevents Development of Allergen-Induced Activation of Invariant NKT Cells and A CD 1 d-Dependent Antagonist Inhibits the Kronenberg (2010) (1)
Abrogation of Anti-Retinal Autoimmunity in Il-10 Transgenic Mice Due to Inhibition of Priming and Effector Function of Auto-Reactive T-Cells (2006) (1)
γδ T cells & intraepithelial lymphocytes (2007) (1)
NKT cell subsets involved in host defense from pulmonary Streptococcus pneumoniae infection (2017) (1)
Cell Antigen Receptors and the lmmunoglobulin Supergene Family Review (2004) (1)
CD 1 class Ilike molecule Nonclassical behavior of the mouse (2001) (1)
Helicobacter pylori cholesteryl alpha-glucosides are critical for bacterial growthand activation of invariant NKT cells (2012) (1)
Idiotype selection is an immunoregulatory mechanism which contributes to the pathogenesis of systemic lupus erythematosus (1988) (1)
Publisher Correction: Innate-like functions of natural killer T cell subsets result from highly divergent gene programs (2019) (1)
Stimulation of a subset of natural killer T cells by CD103+ DC is required for GM-CSF and protection from pneumococcal infection. (2022) (1)
CD1 molecules expressed by enterocytes present peptides distinct from other class I antigen presenting molecules (1995) (1)
Abrogation of Anti-Retinal Autoimmunity in Transgenic Mice Overexpressing IL-10 in a Cell-Specific Fashion (2008) (1)
Invariant NKT cells are crucial for airway inflammation induced by environmental antigens (163.22) (2011) (1)
NKT cells regulate the development of asthma (2005) (1)
Production of an NKT cell stimulatory glycosphingolipid by a prominent member of the human gut microbiota (55.22) (2012) (1)
Phenotypic analysis of the intestinal mucosal lymphocyte population in a lymphocyte transfer model of inflammatory bowel disease in SCID mice (1995) (1)
Thymus-Derived T Cells SCID Mice Reconstituted with Mature , Generation of Intestinal Mucosal Lymphocytes in (1998) (1)
Balance of IL-10 and IL-12 Synthesis Restores Antitumor Reactivity by Altering Specific Inhibition of Cyclooxygenase 2 (1999) (1)
CD1d-dependent activation of NKT cells by Cryptococcus neoformans-pulsed dendritic cells (B172) (2007) (1)
Correction for Unconventional ligand activation of herpesvirus entry mediator signals cell survival, by Timothy C. Cheung (2009) (1)
S1725 Interleukin 10 Acts on Regulatory T Cells to Maintain FOXP3 Expression and Suppressive Function in Mice With Colitis (2010) (1)
The Androgen Deficiency Syndrome in Women (2002) (1)
Cutting Edge: TCRab CD8aa T Cells Are Found in Intestinal Intraepithelial Lymphocytes of Mice That Lack Classical MHC Class I Molecules (1999) (1)
Structure and Recognition of Antigens for Invariant NKT Cells (2012) (1)
Expression of mouse Tla region class I genes in tissue enriched for γδ cells (2004) (1)
Specialized subsets of innate-like T cells and dendritic cells protect from lethal pneumococcal infection in the lung (2021) (1)
Activation in Hepatic Injury NKG2A Inhibits Invariant NKT Cell (2008) (0)
CD1d/NKT cells (PP-006) (2010) (0)
Altered thymic differentiation and modulation of arthritis by invariant NKT cells expressing mutant ZAP70 (2018) (0)
Correction to: A Sensitive and Integrated Approach to Profile Messenger RNA from Samples with Low Cell Numbers. (2018) (0)
In Vivo Effectors: Summary of Part IV (2004) (0)
Molecular and serological diversity of anti-DNA autoantibodies from NZB and (NZB X NZW) F1 mice. (1988) (0)
Adaptive Th 1 and Th 17 Responses Production and Dampening of γ Innate IFN-Autoimmunity by A Mechanism Involving Ameliorates Experimental Ocular Activation of Invariant NKT Cells (2008) (0)
Lymphotoxin receptor beta expression by neutrophils prevents metabolic activation and colitis pathogenesis (2019) (0)
DevelopmentIntrinsically Regulates Invariant NKT Cell ATP-Binding Cassette Transporter G1 (2012) (0)
Intermittent PI3Kδ inhibition sustains anti-tumour immunity and curbs irAEs (2022) (0)
A murine model of NKT cell-mediated liver injury induced by alpha-galactosylceramide/d-galactosamine (2006) (0)
Isolation and characterization of human defensin cDNA clones ( microbicidal peptides / gene cloning / neutrophils / HL-60 cells ) (0)
Phospholipid signals of microbial infection for the human immune system (2015) (0)
Suppression of VαiNKT cell activation by Kupffer cells. (147.5) (2011) (0)
Parathyroid hormone receptor and DNA coding (1992) (0)
MiceIntestinal Inflammation in Gimap5-Deficient Flora-Dependent Wasting Disease and Precedes the Onset of Microbial Loss of T Cell and B Cell Quiescence (2010) (0)
RAMP3 unexplored relevance for innate-T cell immunity (2022) (0)
Transcriptome and chromatin landscape of iNKT cells are shaped by subset differentiation and antigen exposure (2021) (0)
Gut CD4+ T cell phenotypes are a continuum molded by microbes, not by TH archetypes (2021) (0)
Promoter-interacting expression quantitative trait loci are enriched for functional genetic variants (2020) (0)
Hvem expression in innate lymphoid cells mediates host defense against intestinal infection (2016) (0)
Lymphocytes That Participate in Innate Immune Responses (2014) (0)
Functional subsets of intestinal NKT cells (MUC3P.942) (2015) (0)
The 0 Domain of the Qa-2 Molecule Is Defective for CD8 Binding and Cytotoxic T Lymphocyte Activation (2003) (0)
Stunned invariant NKT cells are not anergic, but acquire IL-10-dependent regulatory characteristics (P1052) (2013) (0)
Suppression of V{alpha}iNKT cell activation by Kupffer cells. (2011) (0)
Structure guided engineering of selective HVEM mutants reveal distinct functions binding to LIGHT and BTLA/CD160 (2022) (0)
Identification of Previously Unrecognized CD1d-Restricted Peripheral T Cell Lymphomas (PTCLs) in Mouse and Human Reveals Blocking Anti-CD1d Monoclonal Antibodies As a New Therapeutic Possibility in PTCLs (2014) (0)
Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis (2018) (0)
Gαi2 mediated signaling in mucosal immune homeostasis (2001) (0)
CD4+-mediated colitis in mice is independent of the GPR183 and GPR18 pathways (2022) (0)
Mo1735 Mechanism of Immune Regulation by CD11b+ Myeloid Cells in the Intestine (2011) (0)
Single-cell analysis maps the dynamic landscape of mouse iNKT cell development and identifies Cbfb as a key regulator for early commitment (2020) (0)
Immunological functions of cholesteryl alpha-glucosides in helicobacter pylori-associated inflammation (2011) (0)
+ Patterns of Reactivity to CD1 Mouse CD1-Autoreactive T Cells Have Diverse (2017) (0)
Functional Specialization of Thymus-Derived T Cells in the Intestinal Epithelium. ♦ 41 (1997) (0)
Sensing and recognition of bacteria by NKT cells (44.3) (2007) (0)
Dominant-Negative Mice Receptor II b Biliary Cirrhosis in TGF-Anti-Mitochondrial Antibodies and Primary (2006) (0)
This information is current as Lymphocytes Survival of Activated Mouse CD 4 T A Novel Role for IL-27 in Mediating the Cheroutre and Mitchell Kronenberg (2013) (0)
Abstract 44: Interleukin-27 Signaling is a Critical Regulator of Inflammation in Atherosclerosis (2013) (0)
Population Negatively Regulated by CD1d1 Identifies and Enriches an NK Cell CD1d1 Displayed on Cell Size Beads (2004) (0)
The Crystal Structure of a TL/CD8aa Complex at 2.1A resolution:Implications for Memory T cell Generation, Co-receptor Preference and Affinity (2003) (0)
Kronenberg Carbohydrate specificity of the recognition of diverse glycolipids by natural killer T cells (2009) (0)
NKT cell-derived IL-4 is required early in allergic contact sensitivity (CS) (2003) (0)
Cell Responses to Viral Danger Signals Cutting Edge: The Mechanism of Invariant NKT (2011) (0)
Improved Detection of Cytokines Produced by Invariant NKT Cells (2017) (0)
CD 1-Restricted NK T Cells Galactosylceramide Recognition by Cutting Edge : Structural Requirements for Matsuda , Teruyuki Sakai and Mitchell Kronenberg (1998) (0)
Connecting GWAS SNPs to Target Genes in primary human immune cell types (2020) (0)
The Transcription Factors Thpok And Runx3 Identify Two Distinct CD4−CD8− Double Negative T Cell Populations And Respectively Define Their Commitment In The Helper Or Cytotoxic Fate (2020) (0)
Single cell sequencing reveals mouse MAIT cell diversity (2019) (0)
Microbial triggers for inflammatory disease (SY6-2) Chairpersons: Kiyoshi Takeda, Hilde Cheroutre (2010) (0)
Eli E. Sercarz (1934–2009) (2009) (0)
Allergy and asthma in inner-city children: possible roles of MAIT cells and variation in the home environment (2017) (0)
Single cell sequence analysis reveals mouse MAIT cell diversity at steady state and after infection (2020) (0)
Innate cytokines and natural receptor agonist arrest natural killer T cell patrolling of liver sinusoids (2008) (0)
NKT cells sense bacterial infection and recognize bacterial glycolipids (2007) (0)
Microsoft Word-The alpha and omega of galactosylceramides in T cell immune function.docx (2015) (0)
HVEM expression by innate lymphoid cells protects against enteric bacterial infection (2017) (0)
Epithelial HVEM promotes basement membrane synthesis and intraepithelial T cell survival and migration (2020) (0)
Human Vδ1+ γδ Peripheral T-Cell Lymphoma/Leukemia are Derived from Natural Killer T (NKT) Cells and Might be Treated with Blocking Anti-CD1d Antibody (2016) (0)
Activation of Invariant NKT Cells Ameliorates Experimental Autoimmune Uveitis (EAU) (2006) (0)
Correction: Exosome-like Nanoparticles from Intestinal Mucosal Cells Carry Prostaglandin E2 and Suppress Activation of Liver NKT Cells (2016) (0)
NK T / NK Cell Cross-Talk 14 i α Macrophages Is Required for Optimal V Signaling to γ Cutting Edge : IFN-Brossay (2005) (0)
in T Cell-Mediated Colitis Paradoxical Effect of Reduced Costimulation (2007) (0)
Deficiency in Sphingolipids Has No Effect on Self-antigen Presentation to Invariant NKT Cells (134.17) (2009) (0)
Effects of α GalCer Structural Modifications (2015) (0)
Infection Activation of Invariant NKT Cells during Antigen-Dependent versus-Independent and (2014) (0)
Assessment of the global chromatin landscape and transcriptome of peripheral iNKT cell subsets (2019) (0)
Chapter 5 CXCR 5 regulates Chlamydia tubal pathology in mice and humans (2011) (0)
List of Contributors (2020) (0)
resistance to Salmonella infection in vivo. delta T-cell antigen receptor contribute to Mouse T lymphocytes that express a gamma (2013) (0)
PTH receptor and test method using the same (1998) (0)
Key role for CD103+ DCs in activating lung iNKT cells during Streptococcus pneumoniae infection (2018) (0)
Cytotoxic CD4 T cells control host immunity during viral persistence (2019) (0)
Defining the immune regulatory function of LIGHT specific LTβR interactions in mucosal tissue. (MUC5P.747) (2015) (0)
Sa.57. A Unique LTαβ Dependent Pathway Regulates Thymic Emigration of Vα14i NKT Cells (2006) (0)
NKT Cell Responses to Viral Danger Signals Cutting Edge: The Mechanism of Invariant (2008) (0)
Antigen-dependent and independent NKT cell responses to microbes. (P4379) (2013) (0)
Microbial glycolipid antigen recognition by invariant natural killer T cells (2011) (0)
HVEM expression by intestinal epithelial cells modulates the microbiome and epithelial immunity (2017) (0)
Correction: Interruption of CXCL13-CXCR5 Axis Increases Upper Genital Tract Pathology and Activation of NKT Cells following Chlamydial Genital Infection (2013) (0)
A unique LT alpha beta dependent pathway regulates thymic emigration of V alpha 14i NKT cells (2005) (0)
Down-Regulate Their Antigen Reactivity and Lymphocytes Express Genes That Intraepithelial αα CD 8 + βα Mouse TCR (2007) (0)
SARS-CoV-2 Omicron (B.1.1.529) shows minimal neurotropism in a double-humanized mouse model (2023) (0)
Intestinal epithelium derived IL-10 modulates mucosal immune responses in fabpi-IL-10 transgenic mice (2000) (0)
Metabolic fuel choices control MAIT cell functions at homeostasis and after infection (2022) (0)
Lymphotoxin receptor beta expression by neutrophils is a critical regulator of colitis pathogenesis (2018) (0)
LIGHT-HVEM Signaling in Group3 Innate Lymphoid Cells Protects Against Enteric Bacterial Infection (2018) (0)
Tissue-specific functions of invariant natural killer T cells (2018) (0)
Tissue-Specific Cues Direct Fate Decisions of Mucosal Memory T Cells (39.21) (2009) (0)
Mucosal-Resident T Lymphocytes with Invariant Antigen Receptors (2015) (0)
Invariant NKT Cells Are Crucial For The Th2 Biased Adjuvant Activities Of House Dust Extracts (2011) (0)
Connecting metabolism to inflammation: the role of LACC1 in inflammatory diseases (2020) (0)
Invariant natural killer T cells: front line fighters in the war against pathogenic microbes (2016) (0)
Efficient lipid antigen presentation to NKT cells by targeting CD169/Siglec-1 on macrophages with its glycan ligand. (100.49) (2011) (0)
Hepatic stellate cells regulate T cell responses in cooperation with Kupffer cells. (49.9) (2010) (0)
Membrane lymphotoxin is required early in ontogeny for development of both CD1 dependent and independent NK T cells (2000) (0)
Generation and homeostatic regulation of CD8{alpha}{beta} effector memory T cells by CD8{alpha}{alpha} and its ligand, the thymic leukemia (TL) antigen (2008) (0)
B k through Activation of NF-Carboxylated Glycans Mediate Colitis (2005) (0)
Signals during Differentiation Coordinate Proliferation and Survival Invariant NKT Cells Require Autophagy To (2015) (0)
Neutrophils form elongated shear‐derived particles (SDP) via shedding tethers and slings (2018) (0)
Suppress Activation of Liver NKT Cells and 2 Mucosal Cells Carry Prostaglandin E Exosome-like Nanoparticles from Intestinal (2013) (0)
A unique lymphotoxin alpha beta dependent pathway regulates thymic emigration of V alpha 14iNKT cells (2006) (0)
OR.48. Altered Commensal Microbiota Shape the Development of Innate-Like Lymphocytes (2006) (0)
Mrp1 is involved in lipid presentation and iNKT cell activation by Streptococcus pneumoniae (2018) (0)
Extra-Nuclear and Nuclear Rarα Reciprocally Control Tcr-Induced Proliferation and Differentiation (2019) (0)
A TNF family receptor regulates epithelial innate responses and host defense against pathogenic bacterial infections of the mucosa (49.1) (2012) (0)
Publisher Correction: Innate-like functions of natural killer T cell subsets result from highly divergent gene programs (2019) (0)
Inflammatory bowel diseases (WS-065) Chairpersons: Mamoru Watanabe, Peter Ernst (2010) (0)
HVEM is a TNF family receptor that is a crucial regulator of epithelial and lymphocyte responses in the mucosal immune system (P3192) (2013) (0)
1785 Cutaneous Immunization Rapidly Activates Liver Invariant V (cid:2) 14 NKT Cells Stimulating B-1 B Cells to Initiate T Cell Recruitment for Elicitation of Contact (2003) (0)
Natural Killer T Cell Patrolling of Liver or Microbial Antigens Can Cause Arrest of Cutting Edge: Activation by Innate Cytokines (2008) (0)
Cysteine Cathepsins are Involved in a Double Check-Point during Hepatic NKT Activation (2016) (0)
CD 1 d-Restricted NKT Cells Preventing the Apoptosis of Activated byPromotes Murine Fulminant Liver Failure Lack of Chemokine Receptor CCR 5 (2005) (0)
CD4+ cells found in the inflamed colon of SCID mice with colitis are oligoclonal (1998) (0)
HVEM-BTLA interactions stimulate lung innate immunity following S. pneumoniae infection. (2017) (0)
From genetic variants to diseases: the role of LACC1 in T cells (2022) (0)
Antigen receptor-dependent and -independent regulation of NKT patrolling and activation in liver sinusoids (91.7) (2007) (0)
The antigenic activity of glycosphingolipids with tetrasaccharide sugars from Sphingomonas bacteria to natural killer T cells (2008) (0)
Natural killer T cells (2014) (0)
The Role of Invariant Natural Killer T Cells in Autoimmune Diseases (2020) (0)
Howard Grey (1932–2019) (2020) (0)
RNAtranscripts forI-Jpolypeptides areapparently notencoded between theI-AandI-Esubregions ofthemurinemajor histocompatibili ty complex (1983) (0)
Helicobacterpylori Cholesteryl a -Glucosides Contribute to Its Pathogenicity and Immune Response by Natural Killer T Cells (2013) (0)
HVEM signaling in pulmonary epithelial cells is required for protection against Streptococcus pneumoniae (2019) (0)
Effector Mechanisms Cell Priming and Inhibition of Disease IL-10 Transgenic Mice Due to Reduced T Abrogation of Anti-Retinal Autoimmunity in (2008) (0)
Activation of V alpha 14i NKT cells requires a unique kinetics for the TCR interaction (2003) (0)
Distinct requirements for the cytokine-mediated activation of NKT and NK cells during viral infection. (45.16) (2012) (0)
Hyporesponsiveness by Antigenic Stimulation Induction of Invariant NKT Cell Selective Conditions Are Required for the (2015) (0)
Lymphotoxin-beta receptor expression by neutrophils prevents metabolic activation and colitis pathogenesis (2020) (0)
Repopulation of mucosal lymphocytes in SCID mice (1995) (0)
Targeting MAIT cells by vaccination with S. enterica serotype Typhimurium to prevent lung infections (2020) (0)
Hepatic stellate cells regulate T cell responses in cooperation with Kupffer cells. (2010) (0)
Bacterial Infection Allows for Functional Examination of Adoptively Transferred Mouse Innate Lymphoid Cell Subsets. (2020) (0)
Forthcoming papers (2005) (0)
Generation and homeostatic regulation of CD8αβ effector memory T cells by CD8αα and its ligand, the thymic leukemia (TL) antigen (2008) (0)
Antigen‐specific recognition of bacterial antigens by NKT cells (2008) (0)
Sequential Appearance of T Lymphocyte Subsets in the Developing Mouse Intestine • 23 (1998) (0)
A whole genome mouse siRNA screen to identify novel genes involved in lipid antigen presentation (2017) (0)
Efficient homing of CD4+ cells to the gut mucosa is necessary for colitis pathogenesis, but may not be required for the down regulation of pathogenic T cells (1998) (0)
Natural Killer T Cells as Immunoregulators (2016) (0)
Model of Colitis Oligoclonal Expansion of T Cells in a Mouse Systemic Activation and Antigen-Driven (2000) (0)
Thymus-Derived CD4+CD8+ Cells Reside in Mediastinal Adipose Tissue and the Aortic Arch. (2021) (0)
MAITs onstage in mice and men with three acts for development (2017) (0)
CD1d/NKT cells (WS-006) Chairpersons: Ken-ichiro Seino, Dale Godfrey (2010) (0)

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