Mitsuhiro Yanagida
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- PhD Biological Sciences University of Tokyo
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(Suggest an Edit or Addition)According to Wikipedia, is a Japanese molecular biologist known for research on cell cycle and chromosome structure using the fission yeast Schizosaccharomyces pombe. He was elected as a foreign member of the Royal Society on 11 May 2000.
Mitsuhiro Yanagida's Published Works
Published Works
- CRM1 is responsible for intracellular transport mediated by the nuclear export signal (1997) (1231)
- Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1. (1998) (821)
- DNA topoisomerase II is required for condensation and separation of mitotic chromosomes in S. pombe (1987) (658)
- Cell cycle-dependent specific positioning and clustering of centromeres and telomeres in fission yeast (1993) (515)
- Cut2 proteolysis required for sister-chromatid separation in fission yeast (1996) (490)
- Telomere-led premeiotic chromosome movement in fission yeast. (1994) (483)
- The NDA3 gene of fission yeast encodes β-tubulin: A cold-sensitive nda3 mutation reversibly blocks spindle formation and chromosome movement in mitosis (1984) (455)
- The TPR snap helix: a novel protein repeat motif from mitosis to transcription. (1991) (438)
- The fission yeast dis2 + gene required for chromosome disjoining encodes one of two putative type 1 protein phosphatases (1989) (430)
- Mis16 and Mis18 Are Required for CENP-A Loading and Histone Deacetylation at Centromeres (2004) (424)
- Requirement of Mis6 centromere connector for localizing a CENP-A-like protein in fission yeast. (2000) (422)
- The product of the spindle formation gene sad1+ associates with the fission yeast spindle pole body and is essential for viability (1995) (410)
- Isolation of type I and II DNA topoisomerase mutants from fission yeast: single and double mutants show different phenotypes in cell growth and chromatin organization. (1984) (382)
- Novel potential mitotic motor protein encoded by the fission yeast cut7+ gene (1990) (364)
- Fission yeast genes that confer resistance to staurosporine encode an AP-1-like transcription factor and a protein kinase related to the mammalian ERK1/MAP2 and budding yeast FUS3 and KSS1 kinases. (1991) (340)
- Mitosis : a subject collection from Cold Spring Harbor Perspectives in biology (2015) (333)
- Fission yeast cut3 and cut14, members of a ubiquitous protein family, are required for chromosome condensation and segregation in mitosis. (1994) (327)
- The fission yeast gamma-tubulin is essential for mitosis and is localized at microtubule organizing centers. (1991) (319)
- Priming of Centromere for CENP-A Recruitment by Human hMis18α, hMis18β, and M18BP1 (2007) (316)
- Dynamics of centromeres during metaphase-anaphase transition in fission yeast: Dis1 is implicated in force balance in metaphase bipolar spindle. (1998) (316)
- Distinct, essential roles of type 1 and 2A protein phosphatases in the control of the fission yeast cell division cycle (1990) (308)
- Establishing Biorientation Occurs with Precocious Separation of the Sister Kinetochores, but Not the Arms, in the Early Spindle of Budding Yeast (2000) (306)
- Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1. (2007) (306)
- Isolation and characterization of Schizosaccharomyces pombe cutmutants that block nuclear division but not cytokinesis (1986) (298)
- Characterization of fission yeast cohesin: essential anaphase proteolysis of Rad21 phosphorylated in the S phase. (2000) (285)
- Snap helix with knob and hole: Essential repeats in S. pombe nuclear protein nuc2 + (1990) (282)
- Damage and replication checkpoint control in fission yeast is ensured by interactions of Crb2, a protein with BRCT motif, with Cut5 and Chk1. (1997) (279)
- A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1 (2004) (278)
- Fission yeast condensin complex: essential roles of non-SMC subunits for condensation and Cdc2 phosphorylation of Cut3/SMC4. (1999) (267)
- Schizosaccharomyces pombe atf1+ encodes a transcription factor required for sexual development and entry into stationary phase. (1995) (264)
- Kinesin-related cut 7 protein associates with mitotic and meiotic spindles in fission yeast (1992) (263)
- A low copy number central sequence with strict symmetry and unusual chromatin structure in fission yeast centromere. (1992) (253)
- Priming of centromere for CENP-A recruitment by human hMis18alpha, hMis18beta, and M18BP1. (2007) (247)
- Human centromere chromatin protein hMis12, essential for equal segregation, is independent of CENP-A loading pathway (2003) (241)
- Individual variability in human blood metabolites identifies age-related differences (2016) (240)
- Higher order chromosome structure is affected by cold-sensitive mutations in a Schizosaccharomyces pombe gene crm1+ which encodes a 115- kD protein preferentially localized in the nucleus and its periphery (1989) (240)
- Mitotic spindle pulls but fails to separate chromosomes in type II DNA topoisomerase mutants: uncoordinated mitosis (1986) (239)
- Fission yeast cut5 +, required for S phase onset and M phase restraint, is identical to the radiation-damage repair gene rad4 + (1993) (229)
- Fission yeast minichromosome loss mutants mis cause lethal aneuploidy and replication abnormality. (1994) (228)
- Molecular Cloning and Cell Cycle-dependent Expression of Mammalian CRM1, a Protein Involved in Nuclear Export of Proteins* (1997) (226)
- Mis6, a Fission Yeast Inner Centromere Protein, Acts during G1/S and Forms Specialized Chromatin Required for Equal Segregation (1997) (222)
- Cold‐sensitive and caffeine‐supersensitive mutants of the Schizosaccharomyces pombe dis genes implicated in sister chromatid separation during mitosis. (1988) (213)
- Proper metaphase spindle length is determined by centromere proteins Mis12 and Mis6 required for faithful chromosome segregation. (1999) (213)
- A temperature-sensitive mutation of the Schizosaccharomyces pombe gene nuc2+ that encodes a nuclear scaffold-like protein blocks spindle elongation in mitotic anaphase (1988) (207)
- Fission yeast Cut1 and Cut2 are essential for sister chromatid separation, concentrate along the metaphase spindle and form large complexes. (1996) (203)
- Fission yeast Scm3 mediates stable assembly of Cnp1/CENP-A into centromeric chromatin. (2009) (202)
- Composite motifs and repeat symmetry in S. pombe centromeres: Direct analysis by integration of Notl restriction sites (1989) (196)
- Identification of the pleiotropic cell division cycle gene NDA2 as one of two different α-tubulin genes in schizosaccharomyces pombe (1984) (186)
- Fission Yeast Eso1p Is Required for Establishing Sister Chromatid Cohesion during S Phase (2000) (183)
- S. pombe gene sds22 + essential for a midmitotic transition encodes a leucine-rich repeat protein that positively modulates protein phosphatase-1 (1991) (182)
- A calcineurin-like gene ppb1+ in fission yeast: mutant defects in cytokinesis, cell polarity, mating and spindle pole body positioning. (1994) (182)
- 20S cyclosome complex formation and proteolytic activity inhibited by the cAMP/PKA pathway (1996) (174)
- Chromosome walking shows a highly homologous repetitive sequence present in all the centromere regions of fission yeast (1986) (174)
- Rapamycin sensitivity of the Schizosaccharomyces pombe tor2 mutant and organization of two highly phosphorylated TOR complexes by specific and common subunits (2007) (173)
- Construction of a Not I restriction map of the fission yeast Schizosaccharomyces pombe genome. (1989) (172)
- Structural basis for the diversity of DNA recognition by bZIP transcription factors (2000) (172)
- An electrophoretic karyotype for Schizosaccharomyces pombe by pulsed field gel electrophoresis. (1987) (165)
- Faithful anaphase is ensured by Mis4, a sister chromatid cohesion molecule required in S phase and not destroyed in G1 phase. (1998) (161)
- p93dis1, which is required for sister chromatid separation, is a novel microtubule and spindle pole body-associating protein phosphorylated at the Cdc2 target sites. (1995) (161)
- Cold-sensitive nuclear division arrest mutants of the fission yeast Schizosaccharomyces pombe. (1983) (159)
- Fission yeast cut mutations revisited: control of anaphase. (1998) (154)
- Fission yeast cut5 links nuclear chromatin and M phase regulator in the replication checkpoint control. (1994) (152)
- A 13 kb resolution cosmid map of the 14 Mb fission yeast genome by nonrandom sequence-tagged site mapping (1993) (149)
- Cell division cycle genes nda2 and nda3 of the fission yeast Schizosaccharomyces pombe control microtubular organization and sensitivity to anti-mitotic benzimidazole compounds. (1983) (149)
- Condensin Architecture and Interaction with DNA Regulatory Non-SMC Subunits Bind to the Head of SMC Heterodimer (2002) (149)
- Characterization of Schizosaccharomyces pombe minichromosome deletion derivatives and a functional allocation of their centromere. (1989) (148)
- Cnd2 has dual roles in mitotic condensation and interphase (2002) (143)
- A globular complex formation by Nda1 and the other five members of the MCM protein family in fission yeast (1997) (140)
- Distinct subunit functions and cell cycle regulated phosphorylation of 20S APC/cyclosome required for anaphase in fission yeast. (1997) (140)
- Negative regulation of mitosis by the fission yeast protein phosphatase ppa2. (1993) (138)
- A cell cycle-regulated GATA factor promotes centromeric localization of CENP-A in fission yeast. (2003) (137)
- DNA renaturation activity of the SMC complex implicated in chromosome condensation (1997) (137)
- Cut1 is loaded onto the spindle by binding to Cut2 and promotes anaphase spindle movement upon Cut2 proteolysis (1998) (132)
- The fission yeast cut1 + gene regulates spindle pole body duplication and has homology to the budding yeast ESP1 gene (1990) (132)
- Separase-mediated cleavage of cohesin at interphase is required for DNA repair (2004) (131)
- Two novel protein kinase C‐related genes of fission yeast are essential for cell viability and implicated in cell shape control. (1993) (126)
- Mitotic regulation of protein phosphatases by the fission yeast sds22 protein (1993) (126)
- M phase–specific kinetochore proteins in fission yeast Microtubule-associating Dis1 and Mtc1 display rapid separation and segregation during anaphase (2001) (125)
- Sequential alterations in the nuclear chromatin region during mitosis of the fission yeast Schizosaccharomyces pombe: video fluorescence microscopy of synchronously growing wild-type and cold-sensitive cdc mutants by using a DNA-binding fluorescent probe. (1981) (124)
- pmp1+, a suppressor of calcineurin deficiency, encodes a novel MAP kinase phosphatase in fission yeast (1998) (122)
- Cell cycle mechanisms of sister chromatid separation; Roles of Cut1/separin and Cut2/securin (2000) (122)
- A nitrogen starvation-induced dormant G0 state in fission yeast: the establishment from uncommitted G1 state and its delay for return to proliferation. (1996) (111)
- Phosphorylation of dis2 protein phosphatase at the C‐terminal cdc2 consensus and its potential role in cell cycle regulation. (1994) (110)
- Bypassing anaphase by fission yeast cut9 mutation: requirement of cut9+ to initiate anaphase (1994) (110)
- Fission yeast pap1-dependent transcription is negatively regulated by an essential nuclear protein, crm1 (1992) (109)
- Bir1/Cut17 moving from chromosome to spindle upon the loss of cohesion is required for condensation, spindle elongation and repair (2001) (108)
- Visualization of centromeric and nucleolar DNA in fission yeast by fluorescence in situ hybridization. (1992) (107)
- Coordinated requirements of human topo II and cohesin for metaphase centromere alignment under Mad2-dependent spindle checkpoint surveillance. (2006) (107)
- Condensin but not cohesin SMC heterodimer induces DNA reannealing through protein–protein assembly (2003) (105)
- Highly accurate chemical formula prediction tool utilizing high-resolution mass spectra, MS/MS fragmentation, heuristic rules, and isotope pattern matching. (2012) (104)
- Aberrant mitosis in fission yeast mutants defective in fatty acid synthetase and acetyl CoA carboxylase (1996) (102)
- Protein Interaction Domain Mapping of Human Kinetochore Protein Blinkin Reveals a Consensus Motif for Binding of Spindle Assembly Checkpoint Proteins Bub1 and BubR1 (2011) (101)
- Basic mechanism of eukaryotic chromosome segregation (2005) (96)
- Identification of seven new cut genes involved in Schizosaccharomyces pombe mitosis. (1993) (94)
- HIV-1 Vpr induces cell cycle G2 arrest in fission yeast (Schizosaccharomyces pombe) through a pathway involving regulatory and catalytic subunits of PP2A and acting on both Wee1 and Cdc25. (2001) (94)
- Cdc2 phosphorylation of Crb2 is required for reestablishing cell cycle progression after the damage checkpoint. (1999) (92)
- Cellular quiescence: are controlling genes conserved? (2009) (92)
- Cut8, essential for anaphase, controls localization of 26S proteasome, facilitating destruction of cyclin and Cut2 (2000) (90)
- Dynamic behaviors of DNA molecules in solution studied by fluorescence microscopy. (1983) (89)
- Synergistic roles of the proteasome and autophagy for mitochondrial maintenance and chronological lifespan in fission yeast (2010) (88)
- Genetic control of cellular quiescence in S. pombe (2009) (87)
- Differential expressions of essential and nonessential alpha-tubulin genes in Schizosaccharomyces pombe (1986) (86)
- Evidence for cell cycle-specific, spindle pole body-mediated, nuclear positioning in the fission yeast Schizosaccharomyces pombe. (1997) (86)
- Functional dissection of the phosphorylated termini of fission yeast DNA topoisomerase II (1992) (85)
- Requirement for PP1 phosphatase and 20S cyclosome/APC for the onset of anaphase is lessened by the dosage increase of a novel gene sds23+. (1996) (84)
- Identification of healed terminal DNA fragments in linear minichromosomes of Schizosaccharomyces pombe (1987) (83)
- Dis3, implicated in mitotic control, binds directly to Ran and enhances the GEF activity of RCC1. (1996) (83)
- The fission yeast dis3+ gene encodes a 110-kDa essential protein implicated in mitotic control (1991) (82)
- Genetic and Metabolomic Dissection of the Ergothioneine and Selenoneine Biosynthetic Pathway in the Fission Yeast, S. pombe, and Construction of an Overproduction System (2014) (82)
- Ribonuclease Activity of Dis3 Is Required for Mitotic Progression and Provides a Possible Link between Heterochromatin and Kinetochore Function (2007) (82)
- Regulation of Nuclear Proteasome by Rhp6/Ubc2 through Ubiquitination and Destruction of the Sensor and Anchor Cut8 (2005) (79)
- Histone gene organization of fission yeast: a common upstream sequence. (1985) (79)
- Metabolic profiling of the fission yeast S. pombe: quantification of compounds under different temperatures and genetic perturbation. (2009) (79)
- Fission yeast genes nda1+ and nda4+, mutations of which lead to S-phase block, chromatin alteration and Ca2+ suppression, are members of the CDC46/MCM2 family. (1993) (78)
- A novel essential fission yeast gene pad1+ positively regulates pap1(+)-dependent transcription and is implicated in the maintenance of chromosome structure. (1995) (78)
- The selective continued linkage of centromeres from mitosis to interphase in the absence of mammalian separase (2006) (78)
- Control of localization of a spindle checkpoint protein, Mad2, in fission yeast. (2002) (77)
- Requirement of Chromatid Cohesion Proteins Rad21/Scc1 and Mis4/Scc2 for Normal Spindle-Kinetochore Interaction in Fission Yeast (2002) (75)
- A functional 125-kDa core polypeptide of fission yeast DNA topoisomerase II (1991) (75)
- Essential roles of the RNA polymerase I largest subunit and DNA topoisomerases in the formation of fission yeast nucleolus (1989) (75)
- The regulatory subunits of fission yeast protein phosphatase 2A (PP2A) affect cell morphogenesis, cell wall synthesis and cytokinesis (1996) (74)
- Fission yeast Cut2 required for anaphase has two destruction boxes (1997) (73)
- Isolation and characterization of the fission yeast protein phosphatase gene ppe1+ involved in cell shape control and mitosis. (1993) (73)
- Clearing the way for mitosis: is cohesin a target? (2009) (72)
- Dissection of the essential steps for condensin accumulation at kinetochores and rDNAs during fission yeast mitosis (2008) (72)
- Construction of a mini-chromosome by deletion and its mitotic and meiotic behaviour in fission yeast (1986) (72)
- Schizosaccharomyces pombe cell division cycle under limited glucose requires Ssp1 kinase, the putative CaMKK, and Sds23, a PP2A‐related phosphatase inhibitor (2009) (71)
- Cloning and sequencing of Schizosaccharomyces pombe DNA topoisomerase I gene, and effect of gene disruption. (1987) (68)
- In vitro reactivation of spindle elongation in fission yeast nuc2 mutant cells (1990) (67)
- A novel protein kinase gene ssp1+ is required for alteration of growth polarity and actin localization in fission yeast. (1995) (67)
- Frailty markers comprise blood metabolites involved in antioxidation, cognition, and mobility (2020) (65)
- Specific biomarkers for stochastic division patterns and starvation-induced quiescence under limited glucose levels in fission yeast (2011) (64)
- Regulation of checkpoint kinases through dynamic interaction with Crb2 (2004) (64)
- The reverse, but coordinated, roles of Tor2 (TORC1) and Tor1 (TORC2) kinases for growth, cell cycle and separase-mediated mitosis in Schizosaccharomyces pombe (2011) (63)
- Fission yeast TPR-family protein nuc2 is required for G1-arrest upon nitrogen starvation and is an inhibitor of septum formation. (1995) (62)
- Condensin phosphorylated by the Aurora-B-like kinase Ark1 is continuously required until telophase in a mode distinct from Top2 (2011) (61)
- Two‐step, extensive alterations in the transcriptome from G0 arrest to cell division in Schizosaccharomyces pombe (2007) (59)
- The model unicellular eukaryote, Schizosaccharomyces pombe (2002) (58)
- Nutrient limitations alter cell division control and chromosome segregation through growth-related kinases and phosphatases (2011) (55)
- Fission yeast living mitosis visualized by GFP-tagged gene products. (2001) (55)
- Dissection of fission yeast microtubule associating protein p93Dis1: regions implicated in regulated localization and microtubule interaction (1996) (54)
- A large number of tRNA genes are symmetrically located in fission yeast centromeres. (1991) (54)
- A meiotic mutant of the fission yeast Schizosaccharomyces pombe that produces mature asci containing two diploid spores (1984) (53)
- A Transcript-Specific eIF3 Complex Mediates Global Translational Control of Energy Metabolism. (2016) (52)
- Opposing role of condensin hinge against replication protein A in mitosis and interphase through promoting DNA annealing (2011) (52)
- Mapping epigenetic mutations in fission yeast using whole-genome next-generation sequencing. (2009) (50)
- Frontier questions about sister chromatid separation in anaphase (1995) (50)
- The Crystal Structure of the N-Terminal Region of BUB1 Provides Insight into the Mechanism of BUB1 Recruitment to Kinetochores (2009) (50)
- A novel sequence common to the centromere regions of Schizosaccharomyces pombe chromosomes. (1987) (50)
- Control of metaphase-anaphase progression by proteolysis: cyclosome function regulated by the protein kinase A pathway, ubiquitination and localization. (1999) (49)
- Triploid meiosis and aneuploidy in Schizosaccharomyces pombe: an unstable aneuploid disomic for chromosome III (1985) (48)
- Inner centromere formation requires hMis14, a trident kinetochore protein that specifically recruits HP1 to human chromosomes (2010) (47)
- Fission yeast APC/cyclosome subunits, Cut20/Apc4 and Cut23/Apc8, in regulating metaphase‐anaphase progression and cellular stress responses (1999) (47)
- The S. pombe mitotic regulator Cut12 promotes spindle pole body activation and integration into the nuclear envelope (2009) (46)
- Mechanisms of expression and translocation of major fission yeast glucose transporters regulated by CaMKK/phosphatases, nuclear shuttling, and TOR (2015) (46)
- Involvement of CRM1, a nuclear export receptor, in mRNA export in mammalian cells and fission yeast (1999) (45)
- Unexpected similarities between the Schizosaccharomyces and human blood metabolomes, and novel human metabolites. (2014) (45)
- Epigenetic displacement of HP1 from heterochromatin by HIV-1 Vpr causes premature sister chromatid separation (2011) (45)
- Polo boxes and Cut23 (Apc8) mediate an interaction between polo kinase and the anaphase-promoting complex for fission yeast mitosis (2002) (45)
- Distinct modes of DNA damage response in S. pombe G0 and vegetative cells (2005) (44)
- Cti1/C1D interacts with condensin SMC hinge and supports the DNA repair function of condensin. (2004) (43)
- Fission Yeast Mitotic Regulator Dsk1 Is an SR Protein-specific Kinase* (1998) (43)
- Diverse metabolic reactions activated during 58-hr fasting are revealed by non-targeted metabolomic analysis of human blood (2019) (42)
- Mutations in fission yeast Cut15, an importin α homolog, lead to mitotic progression without chromosome condensation (1998) (42)
- Fission yeast protein kinase C gene homologues are required for protoplast regeneration: a functional link between cell wall formation and cell shape control. (1994) (41)
- The role of Ppe1/PP6 phosphatase for equal chromosome segregation in fission yeast kinetochore (2003) (41)
- The nucleolus is involved in mRNA export from the nucleus in fission yeast (2004) (40)
- An interactive gene network for securin‐separase, condensin, cohesin, Dis1/Mtc1 and histones constructed by mass transformation (2004) (40)
- The fission yeast sts5+ gene is required for maintenance of growth polarity and functionally interacts with protein kinase C and an osmosensing MAP-kinase pathway. (1996) (40)
- Cell biology: Cytoskeleton in the cell cycle (2001) (39)
- Schizosaccharomyces pombe centromere protein Mis19 links Mis16 and Mis18 to recruit CENP‐A through interacting with NMD factors and the SWI/SNF complex (2014) (39)
- Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant (2013) (38)
- RNA pol II transcript abundance controls condensin accumulation at mitotically up-regulated and heat-shock-inducible genes in fission yeast (2015) (37)
- The transition of cells of the fission yeast beta-tubulin mutant nda3-311 as seen by freeze-substitution electron microscopy. Requirement of functional tubulin for spindle pole body duplication. (1990) (37)
- Fission yeast Nda1 and Nda4, MCM homologs required for DNA replication, are constitutive nuclear proteins. (1996) (36)
- Impaired coenzyme A synthesis in fission yeast causes defective mitosis, quiescence-exit failure, histone hypoacetylation and fragile DNA (2012) (36)
- Metabolomic Analysis of Fission Yeast at the Onset of Nitrogen Starvation (2013) (33)
- Identification of Genes Affecting the Toxicity of Anti-Cancer Drug Bortezomib by Genome-Wide Screening in S. pombe (2011) (33)
- Histone H2B mutations in inner region affect ubiquitination, centromere function, silencing and chromosome segregation (2006) (33)
- Use of green fluorescent protein for intracellular protein localization in living fission yeast cells. (1997) (32)
- Identification of cut8+ and cek1+, a novel protein kinase gene, which complement a fission yeast mutation that blocks anaphase (1994) (31)
- Molecular organization of the head of bacteriophage Teven: underlying design principles. (1984) (30)
- Application of the Chromatin Immunoprecipitation Method to Identify in Vivo Protein-DNA Associations in Fission Yeast (2000) (30)
- Cdc48 is required for the stability of Cut1/separase in mitotic anaphase. (2006) (30)
- Securin can have a separase cleavage site by substitution mutations in the domain required for stabilization and inhibition of separase (2006) (30)
- Cdc2 Phosphorylation of the Fission Yeast Dis1 Ensures Accurate Chromosome Segregation (2006) (29)
- Yeast DNA Topoisomerases and Their Structural Genes (1987) (28)
- Gene products required for chromosome separation (1989) (28)
- Caffeine-resistance in fission yeast is caused by mutations in a single essential gene,crm1+ (1996) (27)
- Metabolism of Skin-Absorbed Resveratrol into Its Glucuronized Form in Mouse Skin (2014) (27)
- Sister-chromatid separation and protein dephosphorylation in mitosis. (1991) (27)
- Coupling of DNA replication and mitosis by fission yeast rad4/cut5 (1994) (26)
- Implications for proteasome nuclear localization revealed by the structure of the nuclear proteasome tether protein Cut8 (2011) (26)
- The critical glucose concentration for respiration-independent proliferation of fission yeast, Schizosaccharomyces pombe. (2015) (25)
- Time course analysis of precocious separation of sister centromeres in budding yeast: continuously separated or frequently reassociated? (2001) (25)
- Whole-blood metabolomics of dementia patients reveal classes of disease-linked metabolites (2021) (25)
- Visualization of chromosomes in mitotically arrested cells of the fission yeast Schizosaccharomyces pombe (1983) (24)
- Fission yeast sts1+ gene encodes a protein similar to the chicken lamin B receptor and is implicated in pleiotropic drug-sensitivity, divalent cation-sensitivity, and osmoregulation. (1992) (24)
- Mapping of rRNA genes by integration of hybrid plasmids in Schizosaccharomyces pombe (1984) (24)
- Fission Yeast MAP Kinase Is Required for the Increased Securin-Separase Interaction That Rescues Separase Mutants Under Stress (2006) (24)
- Ascorbic acid 2-O-alpha-glucoside, a stable form of ascorbic acid, rescues human keratinocyte cell line, SCC, from cytotoxicity of ultraviolet light B. (1996) (24)
- Structure of straight flagellar filaments from a mutant of Escherichia coli. (1975) (24)
- Glucose restriction induces transient G2 cell cycle arrest extending cellular chronological lifespan (2016) (23)
- In quiescence of fission yeast, autophagy and the proteasome collaborate for mitochondrial maintenance and longevity (2010) (23)
- Ascorbic acid 2-O-alpha-glucoside-induced redox modulation in human keratinocyte cell line, SCC: mechanisms of photoprotective effect against ultraviolet light B. (1997) (23)
- Identification and characterization of a complex chromosomal replication origin in Schizosaccharomyces pombe. (1992) (22)
- The role of model organisms in the history of mitosis research. (2014) (22)
- Cut1/separase-dependent roles of multiple phosphorylation of fission yeast cohesin subunit Rad21 in post-replicative damage repair and mitosis (2008) (22)
- Tel2: a common partner of PIK‐related kinases and a link between DNA checkpoint and nutritional response? (2007) (22)
- Crystallin synthesis in lens differentiation in cultures of neural retinal cells of chick embryos. (1979) (22)
- Protein phosphatases and cell division cycle control. (1992) (21)
- Whole Blood Metabolomics in Aging Research (2020) (21)
- Very-long-chain fatty acid-containing phospholipids accumulate in fatty acid synthase temperature-sensitive mutant strains of the fission yeast Schizosaccharomyces pombe fas2/lsd1. (2001) (21)
- Histone transcription in cell cycle mutants of fission yeast (1987) (21)
- Universal and essential role of MPFcdc2+ (1988) (20)
- Structure of the fission yeast centromere cen3: Direct analysis of the reiterated inverted region (1991) (20)
- Suppressor mutation analysis combined with 3D modeling explains cohesin’s capacity to hold and release DNA (2018) (20)
- Klf1, a C2H2 Zinc Finger-Transcription Factor, Is Required for Cell Wall Maintenance during Long-Term Quiescence in Differentiated G0 Phase (2013) (19)
- Construction and characterization of centric circular and acentric linear chromosomes in fission yeast (1990) (19)
- Diminishing HDACs by drugs or mutations promotes normal or abnormal sister chromatid separation by affecting APC/C and adherin (2008) (19)
- S-Adenosylmethionine Synthetase Is Required for Cell Growth, Maintenance of G0 Phase, and Termination of Quiescence in Fission Yeast (2018) (19)
- Mis17 Is a Regulatory Module of the Mis6-Mal2-Sim4 Centromere Complex That Is Required for the Recruitment of CenH3/CENP-A in Fission Yeast (2011) (18)
- Genetic regulation of mitotic competence in G0 quiescent cells (2018) (18)
- The kic1 kinase of schizosaccharomyces pombe is a CLK/STY orthologue that regulates cell-cell separation. (2003) (17)
- Higher-order chromosome structure in yeast. (1990) (17)
- Cellular Robustness Conferred by Genetic Crosstalk Underlies Resistance against Chemotherapeutic Drug Doxorubicin in Fission Yeast (2013) (17)
- Yeast tubulin genes. (1987) (17)
- Mis3 with a conserved RNA binding motif is essential for ribosome biogenesis and implicated in the start of cell growth and S phase checkpoint (2000) (16)
- Characterization of Schistosoma mansoni Sds homologue, a leucine-rich repeat protein that interacts with protein phosphatase type 1 and interrupts a G2/M cell-cycle checkpoint. (2006) (15)
- Cut1/separase C‐terminus affects spindle pole body positioning in interphase of fission yeast: pointed nuclear formation (2002) (15)
- Heads and Tails (2004) (14)
- Fission Yeast Pot1 and RecQ Helicase Are Required for Efficient Chromosome Segregation (2010) (14)
- Does a GATA Factor Make the Bed for Centromeric Nucleosomes? (2003) (14)
- Whole-Genome Sequencing of Suppressor DNA Mixtures Identifies Pathways That Compensate for Chromosome Segregation Defects in Schizosaccharomyces pombe (2018) (14)
- Condensin HEAT Subunits Required for DNA Repair, Kinetochore/Centromere Function and Ploidy Maintenance in Fission Yeast (2015) (13)
- A brute force postgenome approach to identify temperature‐sensitive mutations that negatively interact with separase and securin plasmids (2003) (12)
- Suppressor screening reveals common kleisin–hinge interaction in condensin and cohesin, but different modes of regulation (2019) (12)
- A large circular minichromosome of Schizosaccharomyces pombe requires a high dose of type II DNA topoisomerase for its stabilization (1995) (12)
- Three-dimensional structure of the crystalloid in the microbody of Kloeckera sp.: composite crystal model (1982) (12)
- Metabolomics of human fasting: new insights about old questions (2020) (11)
- Does a shift to limited glucose activate checkpoint control in fission yeast? (2014) (11)
- Two budding yeast RAD4 homologs in fission yeast play different roles in the repair of UV-induced DNA damage. (2002) (11)
- CK2 phospho‐independent assembly of the Tel2‐associated stress‐signaling complexes in Schizosaccharomyces pombe (2017) (11)
- Reduced uremic metabolites are prominent feature of sarcopenia, distinct from antioxidative markers for frailty (2021) (11)
- Suppression of a mitotic mutant by tRNA-Ala anticodon mutations that produce a dominant defect in late mitosis (2004) (10)
- Casein kinase II–dependent phosphorylation of DNA topoisomerase II suppresses the effect of a catalytic topo II inhibitor, ICRF-193, in fission yeast (2019) (10)
- Human age-declined saliva metabolic markers determined by LC–MS (2021) (9)
- Decline of ergothioneine in frailty and cognition impairment (2022) (9)
- Regulating sister chromatid separation by separase phosphorylation. (2002) (8)
- ATPase-dependent auto-phosphorylation of the open condensin hinge diminishes DNA binding (2014) (8)
- Condensin locates at transcriptional termination sites in mitosis, possibly releasing mitotic transcripts (2019) (8)
- Establishment of and recovery from damage checkpoint requires sequential interactions of Crb2 with protein kinases Rad3, Chk1, and Cdc2. (2000) (8)
- Whole blood metabolomics of dementia patients reveal classes of disease-linked metabolites (2021) (8)
- Analysis of the cell cycle in the budding yeast Candida albicans by positioning of chromosomes by fluorescence in situ hybridization (FISH) with repetitive sequences (1996) (7)
- Cloning of the Fatty Acid Synthetase β Subunit from Fission Yeast, Coexpression with the α Subunit, and Purification of the Intact Multifunctional Enzyme Complex☆☆☆★ (1998) (7)
- Aging markers in human urine: A comprehensive, non‐targeted LC‐MS study (2020) (7)
- The fission yeast sts 5 + gene is required for maintenance of growth polarity and functionally interacts with protein kinase C and an osmosensing MAP-kinase pathway (1996) (7)
- Dibutyrylcytidine 3′,5′-cyclic monophosphate stimulates neurite outgrowth in rat pheochromocytoma PC12 (1990) (7)
- Inhibition of DNA synthesis of adult rat hepatocytes in primary culture by dibutyrylcytidine 3', 5'-cyclic monophosphate. (1989) (7)
- The (3-prism: a new folding motif (1996) (6)
- Expression of a novel 90-kDa protein, Lsd90, involved in the metabolism of very long-chain fatty acid-containing phospholipids in a mitosis-defective fission yeast mutant. (2007) (6)
- ICRF‐193, an anticancer topoisomerase II inhibitor, induces arched telophase spindles that snap, leading to a ploidy increase in fission yeast (2016) (6)
- The grant-getting game in Japan (1990) (6)
- Measurement of Metabolome Samples Using Liquid Chromatography-Mass Spectrometry, Data Acquisition, and Processing. (2016) (6)
- The putative ceramide-conjugation protein Cwh43 regulates G0 quiescence, nutrient metabolism and lipid homeostasis in fission yeast (2018) (5)
- Replication Meets Cohesion (2000) (5)
- Identification and characterization of a complex chromosomal replication origin inSchizosaccharomyces pombe (2006) (5)
- 10 Genetics of DNA Topoisomerases (1990) (5)
- Metabolomic Analysis of Schizosaccharomyces pombe: Sample Preparation, Detection, and Data Interpretation. (2016) (5)
- Structure of TOR Complexes in Fission Yeast (2010) (5)
- 9 Mitosis and Cytokinesis in the Fission Yeast, Schizosaccharomyces pombe (1997) (5)
- Diverse fission yeast genes required for responding to oxidative and metal stress: Comparative analysis of glutathione‐related and other defense gene deletions (2016) (5)
- A cruciform in the direct repeats of the yeast 2 micron DNA: Selective S1 nuclease cleavage at one of the three homologous palindromes. (1985) (5)
- Ent-kaurane-type diterpenoids from Isodonis Herba activate human hair follicle dermal papilla cells proliferation via the Akt/GSK-3β/β-catenin transduction pathway (2021) (5)
- Structure of Paracrystalline Arrays in the Cell Membrane of Yeasts (1979) (4)
- Chromosome Cohesion and Segregation (2004) (4)
- Nerve growth factor enhances antigen-specific antibody production in ascorbate-stimulated murine splenocytes. (1996) (4)
- Genetic defects in SAPK signalling, chromatin regulation, vesicle transport and CoA-related lipid metabolism are rescued by rapamycin in fission yeast (2018) (4)
- Cloning of a gene from the fission yeast S. pombe which complements E. coli pyrB, the gene for aspartate transcarbamylase (1981) (4)
- From phage to chromosome biology: a personal account. (1999) (4)
- Crystallographic characterization of Pap1-DNA complex. (1998) (3)
- POLYTENE CHROMOSOMES ISOLATED FROM NUCLEI OF TOKUNAGAYUSURIKA AKAMUSHI (DIPTERA, CHIRONOMIDAE): STRUCTURAL TRANSFORMATION CAUSED BY SALT, DETERGENT POLYANIONS AND ENZYMES (1980) (3)
- Isolation of Fission Yeast Condensin Temperature-Sensitive Mutants with Single Amino Acid Substitutions Targeted to Hinge Domain (2019) (3)
- Characterization of detergent dispersed cytidylate cyclase of rat brain. (1990) (3)
- Cell cycle. Replication meets cohesion. . (2000) (3)
- Condensin facilitates sister chromatid separation in actively transcribed DNA regions by relieving the obstructive effect of transcription (2019) (3)
- Preparation of Intracellular Metabolite Extracts from Liquid Schizosaccharomyces pombe Cultures. (2016) (3)
- The dream of every chromosome: equal segregation for a healthy life of the host. (2005) (2)
- [Dynamic structures of DNA, chromatin and chromosomes studied by video fluorescence microscopy]. (1984) (2)
- Cohesin ATPase activities regulate DNA binding and coiled-coil configuration (2022) (2)
- Protein phosphatases in cell division: how vital are they? (1991) (2)
- Fission yeast ceramide ts mutants cwh 43 exhibit defects in G 0 quiescence , nutrient metabolism , and lipid homeostasis (2018) (2)
- Fission Yeast CENP-C (Cnp3) Plays a Role in Restricting the Site of CENP-A Accumulation (2018) (2)
- Infection‐triggered release of tempocholine from bacteriophage T4 studied by electron spin resonance (1978) (2)
- Fission yeast Cut 2 required for anaphase has two destruction boxes 1993 (2013) (2)
- Single amino acid substitutions in hydrophobic cores at a head-coiled coil junction region of cohesin facilitate its release of DNA during anaphase (2022) (1)
- Coordinated Roles of the Putative Ceramide-Conjugation Protein, Cwh43, and a Mn2+-Transporting, P-Type ATPase, Pmr1, in Fission Yeast (2019) (1)
- [Genome mapping of Schizosaccharomyces pombe]. (1993) (1)
- A 38 kb segment containing the cdc2 gene from the left arm of fission yeast chromosome II: sequence analysis and characterization of the genomic DNA and cDNAs encoded on the segment (2000) (1)
- Mass Isolation of Polytene Nuclei of Tokunagayusurikaakamushi (Diptera, Chironomidae): Biochemical and Morphological Characterization (1982) (1)
- Caenorhabditis elegans CED-9 protein isabifunctional cell-death inhibitor (1997) (1)
- Shugoshin protects cohesin complexes at centromeres - Discussion (2005) (1)
- The Basics of Chromosome Segregation (2009) (1)
- A telomerase mutant defective in sister chromatid separation at mitosis. (1997) (1)
- [Metabolomic analysis of human blood, plasma and red blood cells in comparison with eukaryotic microbe]. (2013) (1)
- [Control of M-phase progression by protein phosphatases]. (1998) (0)
- Reply to Mäkinen and Ala-Korpela: Small-scale but accurate metabolomics with high reproducibility for identifying age-related blood metabolites (2016) (0)
- Cell Cycle Control by Protein Phosphatase Genes (1995) (0)
- Cellular responses to glucose restriction; abundance and localization of the glucose transporter are regulated by CaMKK and TORC2 signaling pathways (2015) (0)
- [Blinkin: a kinetochore protein responsible for spindle checkpoint and microtubule-attachment]. (2009) (0)
- [Aim of structural biology (discussion)]. (1999) (0)
- Negative Regulation of the Mis17-Mis6 Centromere Complex by mRNA Decay Pathway and EKC/KEOPS Complex in Schizosaccharomyces pombe (2019) (0)
- Reply to Pan et al.: Whole blood metabolome analysis combined with comprehensive frailty assessment (2020) (0)
- CRYSTAL STRUCTURE OF BZIP TRANSCRIPTION FACTOR PAP1 BOUND TO DNA (2000) (0)
- Regulations of cell surface localization of the fission yeast high-affinity hexose transporter Ght5 by phosphorylation (2017) (0)
- Fission Yeast Pot1 and RecQ Helicase Are Required for Efficient Chromosome Segregation (2014) (0)
- Nucleic Acids Research An electrophoretic karyotype for Schizosaccharomyces pombe by pulsed field gel electrophoresis (2005) (0)
- Genetic analysis of the genes involved in mitosis in fission yeast Schizosaccharomyces pombe (2002) (0)
- [Structural analysis of bacterial flagellar filaments by optical diffraction and filtering (author's transl)]. (1974) (0)
- Characterization ofNovelMutations atthe Schizosaccharomyces pombecdc2Regulatory Phosphorylation Site, Tyrosine 15 (1996) (0)
- Unique spindle phenotype induced by ICRF-193, an anticancer topoisomerase II inhibitor, in fission yeast (2016) (0)
- Molecular mechanisms underlying enhanced glucose uptake and cell cycle arrest triggered by glucose restriction (2016) (0)
- Physical Mapping ofOrigins ofReplication inthe Fission Yeast Schizosaccharomyces pombe (1994) (0)
- Proteolysis and Protein Dephosphorylation Required for Anaphase (1996) (0)
- Bt2cCMP stimulates neurite outgrowth of rat pheochromocytoma PC12 (1990) (0)
- C:\Documents and Settings\usu...hso.default\Cache\1D5C198Ad01 (2009) (0)
- Kinetic analysis of from nitrogen starvation to vegetative cell cylcle in Schizosaccharomyces pombe (2004) (0)
- Two novelprotein kinase C-related genes offission yeastareessential forcell viability andimplicated incell shapecontrol (1995) (0)
- Phosphorylation ofdis2protein phosphatase atthe C-terminal cdc2consensus anditspotential rolein cell cycle regulation (1994) (0)
- [Fission yeast mutants defective in sisiter chromatid separation]. (1999) (0)
- [Studies on the structure of double-helix DNA in the last half century: My study of DNA]. (2003) (0)
- Individual variability of human blood metabolites identify age-related difference (2016) (0)
- ASCB 50TH ANNIVERSARY ESSAY Mostly DNA, a Bit of Glucose, and the Next 50 Years (2010) (0)
- Multiple nutritional phenotypes of fission yeast mutants defective in genes encoding essential mitochondrial proteins (2021) (0)
- Chapter 2 The Basics of Chromosome Segregation (2009) (0)
- Crystal structure of a bZIP transcription factor Pap1 reveals novel DNA recognition (1999) (0)
- Identification of cut8+ and cek1+, a Novel Protein Kinase Gene, Which Complement a Fission Yeast Mutation That Blocks Anaphase (1994) (0)
- Supplementary material from "Genetic defects in SAPK signalling, chromatin regulation, vesicle transport and CoA-related lipid metabolism are rescued by rapamycin in fission yeast" (2018) (0)
- Faithful Sister Chromatid Separation in Mitosis (2000) (0)
- Fission yeastcut5links nuclear chromatin and M phaseregulator inthereplication checkpoint control (1994) (0)
- Introduction: dissection and simplification of chromosome segregation (2005) (0)
- Yeast Sequencing Report A 38 kb segment containing the cdc 2 gene from the left arm of ® ssion yeast chromosome II : sequence analysis and characterization of the genomic DNA and cDNAs encoded on the segment (1999) (0)
- Ask whatever question you like (1997) (0)
- [How does fission yeast cut8 regulate the nuclear localization of proteasome?]. (2006) (0)
- [Proteins of bacteriophage T4 head (author's transl)]. (1973) (0)
- Regulation of the Eukaryotic Cell-Cycle - Final Discussion (1992) (0)
- next-generation sequencing Mapping epigenetic mutations in fission yeast using whole-genome Material Supplemental (2009) (0)
- Mostly DNA, a Bit of Glucose, and the Next 50 Years (2010) (0)
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