Mohamed Hassan Sayegh
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Why Is Mohamed Hassan Sayegh Influential?
(Suggest an Edit or Addition)Mohamed Hassan Sayegh's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Endothelial-to-mesenchymal transition contributes to cardiac fibrosis (2007) (1923)
- Identification of cells initiating human melanomas (2008) (1171)
- Tissue expression of PD-L1 mediates peripheral T cell tolerance (2006) (1123)
- Oral tolerance: immunologic mechanisms and treatment of animal and human organ-specific autoimmune diseases by oral administration of autoantigens. (1994) (937)
- Delayed graft function in kidney transplantation (2004) (929)
- The Programmed Death-1 (PD-1) Pathway Regulates Autoimmune Diabetes in Nonobese Diabetic (NOD) Mice (2003) (754)
- Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance (1999) (658)
- The role of T-cell costimulatory activation pathways in transplant rejection. (1998) (605)
- ABCB5-mediated doxorubicin transport and chemoresistance in human malignant melanoma. (2005) (566)
- CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2 (1995) (564)
- Quantifying the Frequency of Alloreactive T Cells In Vivo: New Answers to an Old Question1 (2001) (539)
- Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment (2000) (526)
- Antibody-induced transplant arteriosclerosis is prevented by graft expression of anti-oxidant and anti-apoptotic genes (1998) (513)
- Critical Role of the Programmed Death-1 (PD-1) Pathway in Regulation of Experimental Autoimmune Encephalomyelitis (2003) (509)
- Immunosuppressive strategies in transplantation (1999) (452)
- Homeostatic proliferation is a barrier to transplantation tolerance (2004) (444)
- Effects of explosive brain death on cytokine activation of peripheral organs in the rat. (1998) (433)
- Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice. (2011) (426)
- Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection. (1996) (421)
- Anaritide in Acute Tubular Necrosis (1997) (408)
- Transplantation 50 years later--progress, challenges, and promises. (2004) (408)
- A critical role for the programmed death ligand 1 in fetomaternal tolerance (2005) (395)
- Extrathymic T Cell Deletion and Allogeneic Stem Cell Engraftment Induced with Costimulatory Blockade Is Followed by Central T Cell Tolerance (1998) (375)
- Programmed death 1 ligand signaling regulates the generation of adaptive Foxp3+CD4+ regulatory T cells (2008) (374)
- Immunomodulatory Function of Bone Marrow-Derived Mesenchymal Stem Cells in Experimental Autoimmune Type 1 Diabetes1 (2009) (373)
- A novel mechanism of action for anti-thymocyte globulin: induction of CD4+CD25+Foxp3+ regulatory T cells. (2006) (368)
- Immunomodulation by Mesenchymal Stem Cells A Potential Therapeutic Strategy for Type 1 Diabetes (2008) (331)
- Insulin-induced remission in new-onset NOD mice is maintained by the PD-1–PD-L1 pathway (2006) (313)
- Indirect allorecognition of major histocompatibility complex allopeptides in human renal transplant recipients with chronic graft dysfunction. (1997) (307)
- A novel role of CD4 Th17 cells in mediating cardiac allograft rejection and vasculopathy (2008) (305)
- T‐cell costimulatory pathways in allograft rejection and tolerance (2003) (297)
- Regulatory functions of CD8+CD28- T cells in an autoimmune disease model. (2003) (294)
- Immunologic tolerance to renal allografts after bone marrow transplants from the same donors. (1991) (275)
- Favorably tipping the balance between cytopathic and regulatory T cells to create transplantation tolerance. (2003) (271)
- Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis. (2001) (245)
- Regulation of Progenitor Cell Fusion by ABCB5 P-glycoprotein, a Novel Human ATP-binding Cassette Transporter* (2003) (243)
- The role of CD80, CD86, and CTLA4 in alloimmune responses and the induction of long-term allograft survival. (1999) (242)
- Immunomodulation by Mesenchymal Stem Cells (2008) (241)
- Regulatory CD25+ T cells in human kidney transplant recipients. (2003) (236)
- Calcineurin Inhibitors: 40 Years Later, Can’t Live Without … (2013) (235)
- The role of the B7 costimulatory pathway in experimental cold ischemia/reperfusion injury. (1997) (233)
- Maternal Acceptance of the Fetus: True Human Tolerance (2007) (232)
- CD28-B7 costimulatory blockade by CTLA4Ig prevents actively induced experimental autoimmune encephalomyelitis and inhibits Th1 but spares Th2 cytokines in the central nervous system. (1995) (228)
- The roles of the new negative T cell costimulatory pathways in regulating autoimmunity. (2004) (226)
- Proinflammatory functions of vascular endothelial growth factor in alloimmunity. (2003) (225)
- Allograft rejection mediated by memory T cells is resistant to regulation (2007) (205)
- Mechanisms of T cell recognition of alloantigen. The role of peptides. (1994) (205)
- Predictors of mortality and the provision of dialysis in patients with acute tubular necrosis. The Auriculin Anaritide Acute Renal Failure Study Group. (1998) (202)
- CD4+ T Cells Mediate Abscess Formation in Intra-abdominal Sepsis by an IL-17-Dependent Mechanism 1 (2003) (199)
- Costimulatory pathways in transplantation: challenges and new developments (2009) (194)
- Role of the Programmed Death-1 Pathway in Regulation of Alloimmune Responses In Vivo1 (2005) (193)
- Chronic cardiac rejection in the LEW to F344 rat model. Blockade of CD28-B7 costimulation by CTLA4Ig modulates T cell and macrophage activation and attenuates arteriosclerosis. (1996) (183)
- CD28-B7 blockade prevents the development of experimental autoimmune glomerulonephritis. (2000) (182)
- Memory T cells: a hurdle to immunologic tolerance. (2003) (177)
- The role of novel T cell costimulatory pathways in autoimmunity and transplantation. (2002) (176)
- CTLA4 signals are required to optimally induce allograft tolerance with combined donor-specific transfusion and anti-CD154 monoclonal antibody treatment. (1999) (174)
- Kinetics of expression of costimulatory molecules and their ligands in murine relapsing experimental autoimmune encephalomyelitis in vivo. (1998) (172)
- Blockade of T-cell costimulation prevents development of experimental chronic renal allograft rejection. (1996) (172)
- Organ trafficking and transplant tourism and commercialism : the declaration of Istanbul (2008) (170)
- Analysis of the Role of Negative T Cell Costimulatory Pathways in CD4 and CD8 T Cell-Mediated Alloimmune Responses In Vivo1 (2005) (165)
- Accelerated Memory Cell Homeostasis during T Cell Depletion and Approaches to Overcome It (2006) (160)
- The Programmed Death-1 Ligand 1:B7-1 Pathway Restrains Diabetogenic Effector T Cells In Vivo (2011) (159)
- The role of the ICOS-B7h T cell costimulatory pathway in transplantation immunity. (2003) (157)
- Induction of immunity and oral tolerance with polymorphic class II major histocompatibility complex allopeptides in the rat. (1992) (156)
- Is the administration of dopamine associated with adverse or favorable outcomes in acute renal failure? Auriculin Anaritide Acute Renal Failure Study Group. (1996) (152)
- The Link between the PDL1 Costimulatory Pathway and Th17 in Fetomaternal Tolerance (2011) (150)
- Role of indirect allorecognition in allograft rejection. (1996) (148)
- Upregulation of cytokines associated with macrophage activation in the Lewis-to-F344 rat transplantation model of chronic cardiac rejection. (1995) (147)
- The role of CD154-CD40 versus CD28-B7 costimulatory pathways in regulating allogeneic Th1 and Th2 responses in vivo. (2000) (146)
- A Link between PDL1 and T Regulatory Cells in Fetomaternal Tolerance1 (2007) (143)
- Thymic recognition of class II major histocompatibility complex allopeptides induces donor-specific unresponsiveness to renal allografts. (1993) (141)
- Chronic allograft dysfunction: mechanisms and new approaches to therapy. (2000) (140)
- Targeting CD22 Reprograms B-Cells and Reverses Autoimmune Diabetes (2008) (138)
- Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function (2007) (138)
- Mechanisms of acquired thymic unresponsiveness to renal allografts. Thymic recognition of immunodominant allo-MHC peptides induces peripheral T cell anergy. (1994) (137)
- Endothelial Cells Modify the Costimulatory Capacity of Transmigrating Leukocytes and Promote Cd28-Mediated Cd4+ T Cell Alloactivation (1999) (136)
- Induction of "infectious" tolerance to MHC-incompatible cardiac allografts in CD4 monoclonal antibody-treated sensitized rat recipients. (1996) (134)
- Enzyme-linked immunosorbent spot assay analysis of peripheral blood lymphocyte reactivity to donor HLA-DR peptides: potential novel assay for prediction of outcomes for renal transplant recipients. (2002) (134)
- Type 2 helper T cell-type cytokines and the development of "infectious" tolerance in rat cardiac allograft recipients. (1997) (131)
- CD28-independent Costimulation of T Cells in Alloimmune Responses1 (2001) (131)
- Cutting Edge: Recipient MHC Class II Expression Is Required to Achieve Long-Term Survival of Murine Cardiac Allografts After Costimulatory Blockade1 (2001) (131)
- Critical, but Conditional, Role of OX40 in Memory T Cell-Mediated Rejection1 (2006) (130)
- Specificity of CD4+CD25+ Regulatory T Cell Function in Alloimmunity1 (2006) (129)
- Late blockade of T cell costimulation interrupts progression of experimental chronic allograft rejection. (1998) (129)
- Anti-CD154 or CTLA4Ig obviates the need for thymic irradiation in a non-myeloablative conditioning regimen for the induction of mixed hematopoietic chimerism and tolerance. (1999) (129)
- Oral, but not intravenous, alloantigen prevents accelerated allograft rejection by selective intragraft Th2 cell activation. (1993) (128)
- Congenic Mesenchymal Stem Cell Therapy Reverses Hyperglycemia in Experimental Type 1 Diabetes (2010) (128)
- Indirect recognition of allopeptides promotes the development of cardiac allograft vasculopathy (2001) (128)
- Transplant nephrectomy improves survival following a failed renal allograft. (2010) (126)
- Peripheral Deletion After Bone Marrow Transplantation with Costimulatory Blockade Has Features of Both Activation-Induced Cell Death and Passive Cell Death1 (2001) (125)
- Challenges to achieving clinical transplantation tolerance. (2001) (125)
- Binding of activated protein C to a specific receptor on human mononuclear phagocytes inhibits intracellular calcium signaling and monocyte-dependent proliferative responses. (1995) (124)
- Anaritide in acute tubular necrosis. Auriculin Anaritide Acute Renal Failure Study Group. (1997) (124)
- Mechanisms of acquired thymic tolerance in experimental autoimmune encephalomyelitis: thymic dendritic-enriched cells induce specific peripheral T cell unresponsiveness in vivo (1995) (123)
- Donor antigen is necessary for the prevention of chronic rejection in CTLA4Ig-treated murine cardiac allograft recipients. (1997) (121)
- The Novel Costimulatory Programmed Death Ligand 1/B7.1 Pathway Is Functional in Inhibiting Alloimmune Responses In Vivo (2011) (120)
- Inhibition of CD26/dipeptidyl peptidase IV activity in vivo prolongs cardiac allograft survival in rat recipients. (1997) (118)
- Regulation by CD25+ lymphocytes of autoantigen-specific T-cell responses in Goodpasture's (anti-GBM) disease. (2003) (118)
- Zeisberg, E.M. et al. Endothelial-to-mesenchymal transition contributes to cardiac fibrosis. Nat. Med. 13, 952-961 (2007) (117)
- Critical Role of OX40 in CD28 and CD154-Independent Rejection1 (2004) (114)
- The emerging role of T cell Ig mucin 1 in alloimmune responses in an experimental mouse transplant model. (2008) (112)
- CD70 Signaling Is Critical for CD28-Independent CD8+ T Cell-Mediated Alloimmune Responses In Vivo1 (2005) (111)
- Role of podocyte B7-1 in diabetic nephropathy. (2014) (110)
- Why do we reject a graft? Role of indirect allorecognition in graft rejection. (1999) (109)
- The in vivo mechanism of action of CTLA4Ig. (1996) (108)
- Mechanisms of PDL1-mediated regulation of autoimmune diabetes. (2007) (108)
- Mechanisms of allo-recognition. Recognition by in vivo-primed T cells of specific major histocompatibility complex polymorphisms presented as peptides by responder antigen-presenting cells. (1994) (108)
- Differential Role of Programmed Death-Ligand 1 and Programmed Death-Ligand 2 in Regulating the Susceptibility and Chronic Progression of Experimental Autoimmune Encephalomyelitis1 (2006) (106)
- CD28-b7 blockade in organ dysfunction secondary to cold ischemia/reperfusion injury. (1997) (105)
- PDL1 Is Required for Peripheral Transplantation Tolerance and Protection from Chronic Allograft Rejection1 (2007) (105)
- New Insights Into the Interactions Between T-Cell Costimulatory Blockade and Conventional Immunosuppressive Drugs (2002) (103)
- Targeting Signal 1 Through CD45RB Synergizes with CD40 Ligand Blockade and Promotes Long Term Engraftment and Tolerance in Stringent Transplant Models1 (2001) (102)
- CTLA4-Ig: a novel immunosuppressive agent (2000) (100)
- CD4+ mononuclear cells induce cytokine expression, vascular smooth muscle cell proliferation, and arterial occlusion after endothelial injury. (1994) (100)
- Prevention of chronic rejection in mouse aortic allografts by combined treatment with CTLA4-Ig and anti-CD40 ligand monoclonal antibody. (1997) (100)
- THE CD154-CD40 COSTIMULATORY PATHWAY IN TRANSPLANTATION (2002) (99)
- Regulatory functions of self-restricted MHC class II allopeptide-specific Th2 clones in vivo. (2001) (97)
- The Role of the CD134-CD134 Ligand Costimulatory Pathway in Alloimmune Responses In Vivo 1 (2003) (97)
- The role of CC chemokine receptor 5 (CCR5) in islet allograft rejection. (2002) (97)
- Mechanisms Underlying Blockade of Allograft Acceptance by TLR Ligands1 (2008) (96)
- Alloreactivity in renal transplant recipients with and without chronic allograft nephropathy. (2004) (94)
- Long-Term Heart Transplant Survival by Targeting the Ionotropic Purinergic Receptor P2X7 (2013) (94)
- Chronic Rejection in Experimental Cardiac Transplantation: Studies in the Lewis‐F344 Model (1993) (93)
- Neural stem/progenitor cells express costimulatory molecules that are differentially regulated by inflammatory and apoptotic stimuli. (2004) (93)
- CD4+ T Cells Regulate Surgical and Postinfectious Adhesion Formation (2002) (93)
- DOWN‐REGULATION OF THE IMMUNE RESPONSE TO HISTOCOMPATIBILITY ANTIGENS AND PREVENTION OF SENSITIZATION BY SKIN ALLOGRAFTS BY ORALLY ADMINISTERED ALLOANTIGEN1 (1992) (93)
- CD28-independent induction of experimental autoimmune encephalomyelitis. (2001) (90)
- Th1 cytokines, programmed cell death, and alloreactive T cell clone size in transplant tolerance. (2002) (89)
- Role of CXC chemokine receptor 3 pathway in renal ischemic injury. (2006) (89)
- Requirement of homotypic NK-cell interactions through 2B4(CD244)/CD48 in the generation of NK effector functions. (2006) (89)
- Critical Role of Donor Tissue Expression of Programmed Death Ligand-1 in Regulating Cardiac Allograft Rejection and Vasculopathy (2008) (88)
- Indirect Allorecognition of Mismatched Donor HLA Class II Peptides in Lung Transplant Recipients with Bronchiolitis Obliterans Syndrome (2001) (87)
- Physiological Mechanisms of Regulating Alloimmunity: Cytokines, CTLA-4, CD25+ Cells, and the Alloreactive T Cell Clone Size1 (2002) (85)
- Hepatocyte growth factor prevents the development of chronic allograft nephropathy in rats. (2001) (85)
- Alloreactive T Cell Responses and Acute Rejection of Single Class II MHC-Disparate Heart Allografts Are under Strict Regulation by CD4+CD25+ T Cells1 (2005) (84)
- A rendezvous before rejection: Where do T cells meet transplant antigens? (2002) (84)
- Immunomodulatory functions of mesenchymal stem cells (2004) (83)
- Ex vivo treatment of antigen-presenting cells with CTLA4Ig and encephalitogenic peptide prevents experimental autoimmune encephalomyelitis in the Lewis rat. (1996) (82)
- Costimulatory pathways in transplantation (2011) (81)
- Differential Role of CCR2 in Islet and Heart Allograft Rejection: Tissue Specificity of Chemokine/Chemokine Receptor Function In Vivo1 (2004) (81)
- Cutting Edge: Transplantation Tolerance through Enhanced CTLA-4 Expression 1 (2003) (78)
- CD28-B7 T cell costimulatory blockade by CTLA4Ig in the rat renal allograft model: inhibition of cell-mediated and humoral immune responses in vivo. (1996) (77)
- Thymic Dendritic Cells Express Inducible Nitric Oxide Synthase and Generate Nitric Oxide in Response to Self- and Alloantigens1 (2000) (77)
- Interleukin-10+ Regulatory B Cells Arise Within Antigen-Experienced CD40+ B Cells to Maintain Tolerance to Islet Autoantigens (2014) (77)
- Kaposi's sarcoma after renal transplantation. (1997) (76)
- The role of autoimmunity in islet allograft destruction: major histocompatibility complex class II matching is necessary for autoimmune destruction of allogeneic islet transplants after T-cell costimulatory blockade. (2002) (75)
- CD4 mAb therapy modulates alloantibody production and intracardiac graft deposition in association with selective inhibition of Th1 lymphokines. (1993) (75)
- Effect of the Purinergic Inhibitor Oxidized ATP in a Model of Islet Allograft Rejection (2013) (75)
- Cellular and humoral mechanisms of vascularized allograft rejection induced by indirect recognition of donor MHC allopeptides. (1999) (75)
- The indirect pathway of allorecognition. The occurrence of self-restricted T cell recognition of allo-MHC peptides early in acute renal allograft rejection and its inhibition by conventional immunosuppression. (1995) (74)
- Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells (2009) (74)
- Acquired tolerance to experimental autoimmune encephalomyelitis by intrathymic injection of myelin basic protein or its major encephalitogenic peptide (1993) (73)
- Modulation of Tissue-Specific Immune Response to Cardiac Myosin Can Prolong Survival of Allogeneic Heart Transplants1 (2002) (73)
- T cell costimulatory pathways: promising novel targets for immunosuppression and tolerance induction. (1995) (71)
- Targeting the CXCR4–CXCL12 Axis Mobilizes Autologous Hematopoietic Stem Cells and Prolongs Islet Allograft Survival via Programmed Death Ligand 1 (2011) (70)
- DEPLETING ANTI-CD4 MONOCLONAL ANTIBODY CURES NEW-ONSET DIABETES, PREVENTS RECURRENT AUTOIMMUNE DIABETES, AND DELAYS ALLOGRAFT REJECTION IN NONOBESE DIABETIC MICE1 (2004) (69)
- CD28-B7-mediated T cell costimulation in chronic cardiac allograft rejection: differential role of B7-1 in initiation versus progression of graft arteriosclerosis. (2001) (69)
- Avoidance of cyclosporine in renal transplantation: effects of daclizumab, mycophenolate mofetil, and steroids. (2000) (69)
- In Vitro and In Vivo Studies of IgG-derived Treg Epitopes (Tregitopes): A Promising New Tool for Tolerance Induction and Treatment of Autoimmunity (2012) (68)
- The role of donor and recipient B7-1 (CD80) in allograft rejection. (1997) (68)
- Immunosuppressive drugs and Tregs: a critical evaluation! (2009) (68)
- Human HTm4 is a hematopoietic cell cycle regulator. (2002) (68)
- Clinical Transplantation Tolerance: Many Rivers to Cross (2007) (67)
- Specific MDR1 P-Glycoprotein Blockade Inhibits Human Alloimmune T Cell Activation In Vitro1 (2001) (66)
- The relative contribution of direct and indirect antigen recognition pathways to the alloresponse and graft rejection depends upon the nature of the transplant. (2002) (65)
- Mechanisms of acquired thymic tolerance in vivo: intrathymic injection of antigen induces apoptosis of thymocytes and peripheral T cell anergy. (1998) (65)
- Up-regulation of endothelin-1 mRNA and peptide expression in rat cardiac allografts with rejection and arteriosclerosis. (1995) (65)
- Differential role of programmed death-ligand 1 [corrected] and programmed death-ligand 2 [corrected] in regulating the susceptibility and chronic progression of experimental autoimmune encephalomyelitis. (2006) (64)
- Finally, CTLA4Ig graduates to the clinic. (1999) (63)
- Colchicine interferes with L-selectin and leukocyte function-associated antigen-1 expression on human T lymphocytes and inhibits T cell activation. (1996) (62)
- Chronic blockade of CD28-B7-mediated T-cell costimulation by CTLA4Ig reduces intimal thickening in MHC class I and II incompatible mouse heart allografts. (1997) (62)
- A Novel Clinically Relevant Strategy to Abrogate Autoimmunity and Regulate Alloimmunity in NOD Mice (2010) (62)
- Role of indirect allorecognition in experimental late acute rejection. (1997) (62)
- The effects of nondepleting CD4 targeted therapy in presensitized rat recipients of cardiac allografts. (1996) (61)
- Distinct functions of autoreactive memory and effector CD4+ T cells in experimental autoimmune encephalomyelitis. (2008) (61)
- Endothelin in organ transplantation. (1996) (61)
- T-cell costimulatory blockade in experimental chronic cardiac allograft rejection: effects of cyclosporine and donor antigen. (1997) (59)
- New reagents on the horizon for immune tolerance. (2007) (59)
- Allograft Rejection in a New Allospecific CD4+ TCR Transgenic Mouse (2003) (59)
- Essential Role of PDL1 Expression on Nonhematopoietic Donor Cells in Acquired Tolerance to Vascularized Cardiac Allografts (2011) (58)
- Role of ICOS pathway in autoimmune and alloimmune responses in NOD mice. (2008) (58)
- CD28-B7 T cell costimulatory blockade by CTLA4Ig in sensitized rat recipients: induction of transplantation tolerance in association with depressed cell-mediated and humoral immune responses. (1997) (57)
- Bacterial Pathogens Induce Abscess Formation by CD4+ T-Cell Activation via the CD28–B7-2 Costimulatory Pathway (2000) (56)
- Mechanisms of indirect allorecognition in graft rejection: class II MHC allopeptide-specific T cell clones transfer delayed-type hypersensitivity responses in vivo. (1996) (56)
- Both CD80 and CD86 co-stimulatory molecules regulate allergic pulmonary inflammation. (1998) (56)
- Safety and efficacy of a calcineurin inhibitor avoidance regimen in pediatric renal transplantation. (2006) (56)
- Different Costimulatory and Growth Factor Requirements for CD4+ and CD8+ T Cell-Mediated Rejection 1 (2004) (56)
- Multicenter Analysis of Immune Biomarkers and Heart Transplant Outcomes: Results of the Clinical Trials in Organ Transplantation‐05 Study (2016) (55)
- CTLA-4 up-regulation plays a role in tolerance mediated by CD45 (2001) (54)
- T-Cell Costimulatory Pathways in Allograft Rejection and Tolerance (2005) (54)
- Anti-CD28 monoclonal antibody therapy prevents chronic rejection of renal allografts in rats. (2002) (53)
- The CD154-CD40 T Cell Costimulation Pathway Is Required for Host Sensitization of CD8+ T Cells by Skin Grafts Via Direct Antigen Presentation1 (2002) (52)
- Acquired systemic tolerance to rat cardiac allografts induced by intrathymic inoculation of synthetic polymorphic MHC class I allopeptides. (1996) (51)
- The role of B/T costimulatory signals in the immunopotentiating activity of neisserial porin. (1999) (50)
- Peptide-mediated immunosuppression. (1997) (50)
- Blockade of the Programmed Death-1 (PD1) Pathway Undermines Potent Genetic Protection from Type 1 Diabetes (2014) (50)
- Interactions between cyclosporine and newer antidepressant medications. (1998) (49)
- Acquired thymic tolerance: role of CTLA4 in the initiation and maintenance of tolerance in a clinically relevant autoimmune disease model. (1999) (49)
- ABCB5 Identifies Immunoregulatory Dermal Cells. (2015) (49)
- A Novel Clinically Relevant Approach to Tip the Balance Toward Regulation in Stringent Transplant Model (2010) (48)
- Indirect allorecognition of donor class I and II major histocompatibility complex peptides promotes the development of transplant vasculopathy. (2001) (47)
- Blockade of CD28-B7, But Not CD40-CD154, Prevents Costimulation of Allogeneic Porcine and Xenogeneic Human Anti-Porcine T Cell Responses1 (2000) (47)
- Rejection of Mouse Cardiac Allografts by Costimulation in trans1 (2001) (47)
- Role of passive T-cell death in chronic experimental autoimmune encephalomyelitis. (2000) (47)
- A Novel Alloantigen-Specific CD8+PD1+ Regulatory T Cell Induced by ICOS-B7h Blockade In Vivo1 (2007) (47)
- Alloreactive T Cell Responses and Acute Rejection of Single Class II MHC-Disparate Heart Allografts Are under Strict Regulation by CD4+CD25+ T Cells. (2005) (47)
- Mechanism of action of donor-specific transfusion in inducing tolerance: role of donor MHC molecules, donor co-stimulatory molecules, and indirect antigen presentation. (2004) (46)
- Mechanisms of indirect allorecognition: characterization of MHC class II allopeptide-specific T helper cell clones from animals undergoing acute allograft rejection. (1998) (46)
- Tolerance and chronic rejection. (1997) (46)
- Allorecognition and effector pathways of islet allograft rejection in normal versus nonobese diabetic mice. (2003) (45)
- Transplantation tolerance: The concept and its applicability (1999) (45)
- Further Analysis of the T‐Cell Subsets and Pathways of Murine Cardiac Allograft Rejection (2003) (45)
- Costimulatory signal blockade in murine relapsing experimental autoimmune encephalomyelitis (1999) (45)
- Mesenchymal stem cells express serine protease inhibitor to evade the host immune response. (2011) (45)
- Cytokine analysis of human renal allograft aspiration biopsy cultures supernatants predicts acute rejection. (1998) (44)
- Characterization of Donor Dendritic Cells and Enhancement of Dendritic Cell Efflux With cc-Chemokine Ligand 21 (2007) (42)
- New TCR Transgenic Model for Tracking Allospecific CD4 T‐Cell Activation and Tolerance in Vivo (2003) (42)
- Importance of hyperglycemia on the primary function of allogeneic islet transplants1 (2003) (41)
- Dual effects of the alloresponse by Th1 and Th2 cells on acute and chronic rejection of allotransplants (2009) (41)
- T-cell response to cardiac myosin persists in the absence of an alloimmune response in recipients with chronic cardiac allograft rejection. (2002) (41)
- Comparative studies of specific acquired systemic tolerance induced by intrathymic inoculation of a single synthetic Wistar-Furth (RT1U) allo-MHC class I (RT1.AU) peptide or WAG (RT1U)-derived class I peptide. (1998) (40)
- Inhibition of allorecognition by a human class II MHC-derived peptide through the induction of apoptosis. (1999) (40)
- T cell recognition of xeno-MHC peptides during concordant xenograft rejection. (1996) (40)
- Effects of leflunomide and deoxyspergualin in the guinea pig-->rat cardiac model of delayed xenograft rejection: suppression of B cell and C-C chemokine responses but not induction of macrophage lectin. (1997) (40)
- Modulation of surgical fibrosis by microbial zwitterionic polysaccharides. (2005) (39)
- Differential effects of oral versus intrathymic administration of polymorphic major histocompatibility complex class II peptides on mononuclear and endothelial cell activation and cytokine expression during a delayed-type hypersensitivity response. (1994) (39)
- Requirements for induction and maintenance of peripheral tolerance in stringent allograft models. (2005) (39)
- Mechanisms of targeting cd28 by a signaling monoclonal antibody in acute and chronic allograft rejection1 (2002) (39)
- Thromboxane A2 receptor blocking abrogates donor-specific unresponsiveness to renal allografts induced by thymic recognition of major histocompatibility allopeptides (1994) (39)
- Rat intestinal epithelial cells present major histocompatibility complex allopeptides to primed T cells. (1994) (38)
- Downregulation of intragraft IFN-gamma expression correlates with increased IgG1 alloantibody response following intrathymic immunomodulation of sensitized rat recipients. (1995) (38)
- Blocking of mononuclear cell accumulation, cytokine production, and endothelial activation within rat cardiac allografts by CD4 monoclonal antibody therapy. (1992) (37)
- Matrix Embedding Alters the Immune Response Against Endothelial Cells In Vitro and In Vivo (2005) (36)
- In vivo mechanisms of acquired thymic tolerance. (1997) (36)
- Activation of Alloreactive CD8+ T Cells Operates Via CD4-Dependent and CD4-Independent Mechanisms and Is CD154 Blockade Sensitive 1 (2003) (35)
- The thymic way to transplantation tolerance. (1995) (35)
- Regulatory functions of alloreactive Th2 clones in human renal transplant recipients. (2002) (35)
- Involvement of the direct and indirect pathways of allorecognition in tolerance induction. (2001) (34)
- Mechanisms of Tolerance Induced by Donor‐Specific Transfusion and ICOS‐B7h Blockade in a Model of CD4+ T‐Cell‐Mediated Allograft Rejection (2005) (34)
- Interaction Between ICOS‐B7RP1 and B7‐CD28 Costimulatory Pathways in Alloimmune Responses In Vivo (2003) (33)
- Chronic Kidney Disease, Dialysis, and Transplantation (2010) (32)
- Comparative strategies to induce long-term graft acceptance in fully allogeneic renal versus cardiac allograft models by CD28-B7 T cell costimulatory blockade: role of thymus and spleen. (1998) (32)
- Role of peripheral clonal deletion in tolerance induction with bone marrow transplantation and costimulatory blockade. (1999) (32)
- The allocation of cadaver kidneys for transplantation in the United States: consensus and controversy. ASN Transplant Advisory Group. American Society of Nephrology. (1999) (32)
- The Novel Role of SERPINB9 in Cytotoxic Protection of Human Mesenchymal Stem Cells (2011) (31)
- Intact B7‐H3 signaling promotes allograft prolongation through preferential suppression of Th1 effector responses (2012) (31)
- Synthetic MHC class I peptide prolongs cardiac survival and attenuates transplant arteriosclerosis in the Lewis-->Fischer 344 model of chronic allograft rejection. (1997) (31)
- Blocking costimulatory signals to induce transplantation tolerance and prevent autoimmune disease. (1999) (30)
- The role of costimulatory molecules as targets for new immunosuppressives in transplantation. (2000) (30)
- Mechanisms of Oral Tolerance by MHC Peptides (1996) (30)
- Distinct tolerance pathways in sensitized allograft recipients after selective blockade of activation signal 1 or signal 2. (1999) (30)
- Immune parameters affecting adenoviral vector gene therapy in the brain. (1998) (30)
- Role of the ICOS-B7h Costimulatory Pathway in the Pathophysiology of Chronic Allograft Rejection (2005) (29)
- Paradoxical Functions of B7: CD28 Costimulation in a MHC Class II‐Mismatched Cardiac Transplant Model (2009) (29)
- Immune profile of pediatric renal transplant recipients following alemtuzumab induction. (2012) (29)
- Clinical update: immunosuppression minimisation (2007) (29)
- Differential effects of B7-1 blockade in the rat experimental autoimmune encephalomyelitis model. (1997) (29)
- Novel Insights into the Mechanism of Action of FTY720 in a Transgenic Model of Allograft Rejection: Implications for Therapy of Chronic Rejection1 (2006) (29)
- Novel immunotherapeutic strategies using MHC derived peptides. (1996) (28)
- A novel CD154 monoclonal antibody in acute and chronic rat vascularized cardiac allograft rejection1 (2002) (28)
- IL-21 Is an Antitolerogenic Cytokine of the Late-Phase Alloimmune Response (2011) (28)
- CD45RB-targeting strategies for promoting long-term allograft survival and preventingchronic allograft vasculopathy1 (2003) (28)
- Matrix adherence of endothelial cells attenuates immune reactivity: induction of hyporesponsiveness in allo‐ and xenogeneic models (2007) (28)
- Chronic rejection in experimental cardiac transplantation in a rat model. (1994) (27)
- P2X7R mutation disrupts the NLRP3-mediated Th program and predicts poor cardiac allograft outcomes (2018) (27)
- Effects of BWH-4 anti-CD4 monoclonal antibody on rat vascularized cardiac allografts before and after engraftment. (1991) (26)
- P-glycoprotein--a novel therapeutic target for immunomodulation in clinical transplantation and autoimmunity? (2003) (26)
- T-cell co-stimulatory blockade in transplantation: two steps forward one step back! (2013) (26)
- Immunogenicity and reactogenicity of BNT162b2 booster in BBIBP-CorV-vaccinated individuals compared with homologous BNT162b2 vaccination: Results of a pilot prospective cohort study from Lebanon (2021) (25)
- Regulation of Postsurgical Fibrosis by the Programmed Death-1 Inhibitory Pathway1 (2004) (25)
- Immunomodulatory functions of hyaluronate in the LEW-to-F344 model of chronic cardiac allograft rejection. (1999) (24)
- Blockade of CD40L/CD40 costimulatory pathway in a DST presensitization model of islet allograft leads to a state of Allo-Ag specific tolerance and permits subsequent engraftment of donor strain islet or heart allografts. (1998) (24)
- In vitro and in vivo immunomodulatory effects of RDP1258, a novel synthetic peptide. (1998) (24)
- Phenotypic and Functional Differences Between Wild-Type and CCR2−/− Dendritic Cells: Implications for Islet Transplantation (2008) (24)
- Defining Th1 and Th2 Immune Responses in a Reciprocal Cytokine Environment In Vivo1 (2004) (24)
- Immunomodulatory functions of low-molecular weight hyaluronate in an acute rat renal allograft rejection model. (1999) (23)
- Induction of Robust Diabetes Resistance and Prevention of Recurrent Type 1 Diabetes Following Islet Transplantation by Gene Therapy1 (2007) (23)
- Membranous Lupus Nephritis in a Renal Allograft: Response to Mycophenolate Mofetil Therapy (2001) (22)
- CTLA4Ig-Induced Linked Regulation of Allogeneic T Cell Responses1 (2001) (21)
- Clinical transplantation tolerance: the promise and challenges. (2004) (21)
- Intrathymic tolerance in the Lewis-to-F344 chronic cardiac allograft rejection model. (1995) (21)
- Alternative T‐Cell Costimulatory Pathways in Transplant Rejection and Tolerance Induction: Hierarchy or Redundancy? (2003) (20)
- Negative T-cell costimulatory pathways: their role in regulating alloimmune responses. (2008) (20)
- Indirect Recognition of MHC Class I Allopeptides Accelerates Lung Allograft Rejection in Miniature Swine (2005) (20)
- The antagonism of calcineurin inhibitors and costimulatory blockers: fact or fiction? (2004) (20)
- CD160Ig Fusion Protein Targets a Novel Costimulatory Pathway and Prolongs Allograft Survival (2013) (19)
- The alloantibody network following intrathymic immunomodulation of sensitized rat recipients of cardiac allografts. (1995) (19)
- Core Concepts in the Disorders of Fluid, Electrolytes and Acid-Base Balance (2013) (18)
- MECHANISMS OF INDIRECT ALLORECOGNITION (1998) (18)
- Differential role of CD4+ cells in the sensitization and effector phases of accelerated graft rejection. (1991) (18)
- Maintenance pharmacological immunosuppressive strategies in renal transplantation. (1997) (17)
- CD 28B 7 Blockade after Alloantigenic Challenge In Vivo Inhibits Thl Cytokines but Spares Th 2 By (2003) (17)
- Inhibition of the alloimmune response with synthetic nonpolymorphic class II MHC peptides. (1995) (17)
- Nocardial infection in a renal transplant recipient on tacrolimus and mycophenolate mofetil. (1999) (17)
- Blocking cell microtubule assembly inhibits the alloimmune response in vitro and prolongs renal allograft survival by inhibition of Th1 and sparing of Th2 cell function in vivo. (1995) (16)
- Indirect allorecognition promotes the development of cardiac allograft vasculopathy. (2001) (16)
- Detection of cardiac myosin-specific autoimmunity in a model of chronic heart allograft rejection. (2001) (16)
- Recurrence of glomerulonephritis following renal transplantation (1999) (16)
- Chronic Kidney Disease, Dialysis, and Transplantation: A Companion to Brenner and Rector's The Kidney (2019) (16)
- Membranous nephropathy in a patient with renal cell carcinoma. (1991) (16)
- The importance of targeting the CD4+ T cell subset at the time of antigenic challenge for induction of prolonged vascularized allograft survival. (1992) (15)
- TNP-470, an angiogenesis inhibitor, attenuates the development of allograft vasculopathy. (2004) (15)
- Costimulation couture: a designer approach to regulating autoimmunity. (2006) (15)
- Faculty Opinions recommendation of Ex vivo generation of human alloantigen-specific regulatory T cells from CD4(pos)CD25(high) T cells for immunotherapy. (2008) (15)
- Assessment by flow cytometry of intracellular cytokine production in the peripheral blood cells of renal transplant recipients (2004) (15)
- Tolerance and chronic rejection. (2001) (14)
- Class II MHC allopeptide-specific T-cell clones transfer delayed type hypersensitivity responses in vivo. (1997) (14)
- HLA class II-restricted binding of muramyl peptides to B lymphocytes of normal and narcoleptic subjects. (1990) (14)
- Anti-CD4 monoclonal antibody effects cellular hyporesponsiveness and prolongs renal allograft survival in the rat. (1989) (14)
- Cholesterol efflux capacity of high-density lipoprotein correlates with survival and allograft vasculopathy in cardiac transplant recipients. (2016) (14)
- Case record of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 8-2003. A 35-year-old man with early dysfunction of a second renal transplant. (2003) (14)
- Inotuzumab Ozogamicin Murine Analog–Mediated B-Cell Depletion Reduces Anti-islet Allo- and Autoimmune Responses (2011) (13)
- The cell cycle associated protein, HTm4, is expressed in differentiating cellsof the hematopoietic and central nervous system in mice (2005) (13)
- Transplantation tolerance in pediatric recipients: Lessons and challenges (2005) (13)
- Late renal allograft failure secondary to thrombotic microangiopathy-human immunodeficiency virus nephropathy. (1994) (13)
- Regulatory CD 25 T Cells in Human Kidney Transplant Recipients (2003) (13)
- Key role of the alternate complement pathway in hyperacute rejection of rat hearts transplanted into fetal sheep. (1996) (13)
- CTLA4Ig-induced linked regulation of allogeneic T cell responses. (2001) (13)
- Regulatory T Cells Maintain Peripheral Tolerance to Islet Allografts Induced by Intrathymic Injection of MHC Class I Allopeptides1 (1999) (13)
- Induction of immunity and oral tolerance to alloantigen by polymorphic class II major histocompatibility complex allopeptides in the rat. (1993) (12)
- Sijilli: a mobile electronic health records system for refugees in low-resource settings. (2019) (12)
- Measuring T cell alloreactivity to predict kidney transplant outcomes: are we there yet? (2006) (12)
- INTRATHYMIC INJECTION OF DONOR‐SPECIFIC X‐IRRADIATION-SENSITIVE SPLEEN CELLS ABROGATES ACCELERATED REJECTION OF CARDIAC ALLOGRAFTS IN SENSITIZED RATS1 (1994) (12)
- Combination Treatment with Donor-Specific Transfusions and Cyclosporine A Induces Long-Term Survival of Cardiac Allografts in Miniature Swine (2005) (12)
- Donor-specific transplantation unresponsiveness in sensitized rats following treatment with a nondepleting anti-CD4 MAb is associated with selective intragraft sparing of Th2-like cells. (1995) (12)
- Accelerated Allograft Vasculopathy With Rituximab After Cardiac Transplantation. (2019) (11)
- A novel mechanism for the immunomodulatory functions of class II MHC-derived peptides. (2003) (11)
- T-cell recognition of allograft target antigens (2000) (11)
- B cell-targeted therapies in autoimmunity: rationale and progress (2009) (10)
- Current and Future Immunosuppressive Therapies Following Transplantation (2001) (10)
- Dialysis and Transplantation: A Companion to Brenner & Rector's The Kidney (2000) (10)
- Regulatory T cells in transplantation: what we know and what we do not know. (2009) (10)
- Why do we reject a graft? Mechanisms of recognition of transplantation antigens (1996) (10)
- TIM4 Regulates the Anti-Islet Th2 Alloimmune Response (2015) (10)
- Physiologic regulation of alloimmune responses in vivo: the role of CTLA4 and TH1/TH2 cytokines. (2001) (10)
- CTLA 4 Ig graduates to the clinic (1999) (9)
- Erratum: Alloreactive T cell responses and acute rejection of single class II MHC-disparate heart allografts are under strict regulation by CD4 +CD25+ T cells (The Journal of Immunology (2005) 174 (3741-3748)) (2005) (9)
- The role of indirect recognition of donor MHC class II peptides in cardiac transplantation in miniature swine. (2001) (9)
- Effect of hepatocyte growth factor on chronic rejection in rat renal allografts. (1999) (9)
- Induction of transplantation tolerance to fully mismatched cardiac allografts by T cell mediated delivery of alloantigen. (2010) (9)
- CTLA4Ig: effects on cellular and humoral immunity and macrophage activation. (1997) (9)
- The evolution of the immunobiology of co-stimulatory pathways: clinical implications. (2007) (9)
- In Memoriam: Charles Bernard Carpenter (2012) (8)
- Overcoming cardiac allograft vasculopathy (CAV) by inducing tolerance. (2002) (8)
- Role of the CD28:B7 costimulatory interaction in alloimmune responses. (1997) (8)
- Donor antigen and transplant tolerance strategies: it takes two to tango! (2004) (8)
- Promotion of altruistic donation. (2009) (8)
- Clinical transplantation tolerance: a myth no more, but... (2009) (8)
- Targeting CD28 to prevent transplant rejection (2014) (8)
- Transplantation tolerance. A complex scenario awaiting clinical applicability. (2005) (8)
- Use of polyclonal/monoclonal antibody therapies in transplantation (2017) (8)
- Induction of transplantation tolerance by combining non-myeloablative conditioning with delivery of alloantigen by T cells. (2008) (8)
- A novel in vivo regulatory role of P-glycoprotein in alloimmunity. (2010) (8)
- Immunomodulatory function of major histocompatibility complex-derived peptides. (1996) (7)
- Costimulation Blockade in Transplantation. (2019) (7)
- EVIDENCE THAT THERAPEUTIC STRATEGIES TARGETED AT CD4+ CELLS MODULATE ACCELERATED REJECTION OF CARDIAC ALLOGRAFTS IN SENSITIZED RATS BY DIFFERENT MECHANISMS (1992) (7)
- Reversing the brain drain: a Lebanese model (2012) (7)
- Current and future immunosuppressive therapies: impact on chronic allograft dysfunction. (1997) (7)
- A pilot study on the immunological effects of oral administration of donor major histocompatibility complex class II peptides in renal transplant recipients (2008) (7)
- Role of nuclear factor of activated T cell (NFAT) transcription factors in skin and vascularized cardiac allograft rejection. (2011) (6)
- Oral immunization with allogeneic splenocytes inhibits development of accelerated but not acute rejection of cardiac grafts: analysis of intragraft effector mechanisms. (1992) (6)
- Major histocompatibility complex–derived peptides as novel forms of immunosuppression (1999) (6)
- Role of regulatory T cells in the "infectious" tolerance pathway in transplant recipients. (1998) (6)
- CD 28-independent Costimulation of T Cells in Alloimmune Responses 1 (2001) (6)
- The Limits of Linked Suppression for Regulatory T Cells (2016) (6)
- Live Images of Donor Dendritic Cells Trafficking via CX3CR1 Pathway (2016) (6)
- Regulatory T cells maintain peripheral tolerance to islet allografts induced by intrathymic injection of MHC class I allopeptides. (1998) (6)
- T cell costimulatory pathways in allograft rejection and tolerance: what's new? (2007) (6)
- The role of CD 154-CD 40 versus CD 28B 7 costimulatory pathways in regulating allogeneic Th 1 and Th 2 responses in vivo (2000) (6)
- ANALYSIS OF THE ROLE OF NEGATIVE T CELL COSTIMULATORY PATHWAYS IN CD4 AND CD8 MEDIATED ALLOIMMUNE RESPONSES IN VIVO (2004) (6)
- Core concepts in renal transplantation (2012) (5)
- Effect of gonadectomy on epidermal growth factor values in the gastrointestinal tract of male and female CD-1 mice. (1995) (5)
- Intrathymic immunomodulation in sensitized rat recipients of cardiac allografts: requirements for allorecognition pathways. (1997) (5)
- Induction of transplant tolerance by intrathymic inoculation of synthetic MHC class I allopeptides. (1997) (5)
- Th2-type cytokines in the "infectious" tolerance pathway. (1997) (5)
- Intrathymic injection of allogeneic cells induces indefinite survival of cardiac but not small bowel grafts. (1994) (5)
- Looking into the crystal ball: kidney transplantation in 2025 (2009) (5)
- Dawning of a New ASN Journal: Satisfying an Unmet Need in Clinical Research and Education (2005) (5)
- CD 28-independent induction of experimental autoimmune encephalomyelitis (2001) (5)
- Corrigendum to 'Mechanisms of PDL1-mediated regulation of autoimmune diabetes' [Clin. Immunol. 125 (2007) 16-25] (2014) (5)
- Calcineurin inhibitor (CNI) avoidance in pediatric renal transplantation (RTx). (2005) (5)
- Requirements for the induction of allospecific CD8+ suppressor T cells in the rat primary mixed lymphocyte response. CD4+, CD45R+ T cells, or supernatant factor. (1989) (4)
- This information is current as Activation In Vitro Inhibits Human Alloimmune T Cell Specific MDR 1 P-Glycoprotein Blockade Briscoe (2001) (4)
- Imaging cell biology in transplantation (2016) (4)
- Regulating rejection with cell therapy (2008) (4)
- The role of the B 7 costimulatory pathway in experimental cold ischemia / reperfusion injury (2013) (4)
- Faculty Opinions recommendation of PD-L1 negatively regulates CD4+CD25+Foxp3+ Tregs by limiting STAT-5 phosphorylation in patients chronically infected with HCV. (2009) (4)
- Responses In Vivo Costimulatory Pathway in Alloimmune The Role of the CD 134-CD 134 Ligand Yagita and (2003) (4)
- The arduous road to achieving an immunosuppression-free state in kidney transplant recipients (2007) (4)
- Differential role of programmed death-1 ligand and programmed death-2 ligand in regulating the susceptibility and chronic progression of experimental autoimmune encephalomyelitis (2006) (4)
- Inhibition of CD28-B7 T-cell costimulatory activation pathway affects intragraft cytokine and growth factor expression in chronic renal allograft rejection. (1997) (4)
- Identification of human melanoma initiating cells (2008) (4)
- CD4-targeted therapy and CD28-B7 costimulatory blockage may independently induce tolerance in sensitized allograft recipients. (1998) (4)
- CD28-B7 T-cell co-stimulatory blockade potentiates the effects of intrathymic immunomodulation in sensitized graft recipients. (1997) (4)
- Challenges for the translation of T cell costimulatory blockade therapies to the clinic (2002) (4)
- CTLA4Ig and donor-specific transfusion prolongs cardiac allograft survival in the miniature swine. (2001) (3)
- Does belatacept provide equivalent suppression of acute renal transplant rejection to ciclosporin? (2006) (3)
- Global vaccination strategy to eradicate COVID-19: Beyond science (2021) (3)
- TNF:TNF-R T-Cell costimulatory pathways in transplantation. (2001) (3)
- Intrathymic injection of donor splenocytes plus systemic antilymphocyte serum or antilymphocyte serum alone prolongs cardiac allograft survival and inhibits graft arteriosclerosis in the Lewis-to-F344 chronic rejection model. (1995) (3)
- Switching immunosuppressive drugs in kidney transplant recipients: "show me the evidence". (2006) (3)
- Mixed lymphocyte response-generated suppressor cell specificity in humans is major histocompatibility complex-restricted. (1989) (3)
- Live Without Calcineurin Inhibitors : 40 Years Later , Can ' t (2013) (3)
- (208) - Rituximab Induction and Risk of Cardiac Allograft Vasculopathy, Rejection and Death (2017) (3)
- T-cell co-stimulatory blockade in kidney transplantation: back to the bench (2011) (3)
- Developments in the clinical science of transplantation during the 20th century. (1998) (3)
- T cell costimulatory blockade as a novel immune intervention in autoimmune diseases. (2001) (3)
- Intrathymic immunomodulation of sensitized rat recipients of cardiac allografts: requirements for allorecognition pathways. (2000) (3)
- Peptide mediated immunosuppression: new developments. (1998) (3)
- Kidney transplantation principles and practice, 5th edition (2002) (3)
- Importance of the CD28/B7 costimulatory pathway in the development of chronic ductopenic rejection in a new model of orthotopic rat liver allotransplantation. (1997) (3)
- Abrogation of accelerated allograft rejection by intrathymic injection of donor spleen cells is associated with upregulation of donor-reactive IgM, IgG1, and IgG2A, but depression of IgG2B in the circulation and at the graft site. (1995) (2)
- Role of novel T-cell costimulatory pathways in transplantation (2003) (2)
- Immunogenicity and Effectiveness of Primary and Booster Vaccine Combination Strategies during Periods of SARS-CoV-2 Delta and Omicron Variants (2022) (2)
- The Programmed Death-1 (pd-1) Pathway Regulates Peripheral T Cell Tolerance During Autoimmune Diabetes in Nonobese Diabetic (NOD) Mice (2007) (2)
- CTLA 4 Ig-Induced Linked Regulation of Allogeneic T Cell Responses 1 (2001) (2)
- In vivo evidence for the Th1/Th2 paradigm: oral alloantigen-induced modulation of accelerated allograft rejection is associated with dense intragraft IL-4. (1992) (2)
- Divergent Function of Programmed Death-Ligand 1 in Donor Tissue versus Recipient Immune System in a Murine Model of Bronchiolitis Obliterans. (2017) (2)
- Mesenteric and intraepithelial lymphocytes are insufficient to cause rejection but able to mediate lethal graft-versus-host disease in small bowel transplants. (1994) (2)
- Complement dances with T cells. (2008) (2)
- New Immunosuppressive modalities and anti-rejection approaches in organ transplantation (1994) (2)
- Prolongation of survival and preservation of allograft structure and function by a signaling CD28 mAB in a rat model of chronic kidney rejection. (2001) (2)
- Faculty Opinions recommendation of Interleukin-17 is required for T helper 1 cell immunity and host resistance to the intracellular pathogen Francisella tularensis. (2010) (2)
- CD70-CD27 is a critical CD28-independent costimulatory pathway for alloimmune CD8+T cell responses (2003) (2)
- BCL-Xl AUGMENTS T CELL SURVIVAL IN THE ABSENCE OF COSTIMULATION AND BLOCKS IMMUNOSUPPRESSION WITH CTLA4IG. (1998) (2)
- Achieving clinical transplant tolerance: what are the hurdles? (2001) (2)
- Dialysis and transplantation (2013) (1)
- Regulation of Alloimmune Responses In Vivo Role of the Programmed Death-1 Pathway in Turka and (2005) (1)
- Changes in Plasma Levels of VEGF-C and Endothelin-1 During the First Post-Transplant Year Are Predictive of Cardiac Allograft Vasculopathy: Results From the CTOT-05 Study.: Abstract# A23 (2014) (1)
- Preclinical design of less immunogenic biologics: Tregitopes and Tolerance (144.28) (2010) (1)
- Chapter 88 – Diagnosis and Management of Renal Allograft Dysfunction (2008) (1)
- Indirect allorecognition of MHC class II peptides accellerates cardiac allograft rejection in miniature swine (2003) (1)
- Distinct tolerance pathways in sensitized rat recipients after blockade of activation signal 1 and signal 2. (1999) (1)
- SENSITIZATION AGAINST DONOR MISMATCHED HLA CLASS II PEPTIDES IN LUNG TRANSPLANT RECIPIENTS WITH BRONCHIOLITIS OBLITERANS SYNDROME (1999) (1)
- Faculty Opinions recommendation of Regulation of conformer-specific activation of the integrin LFA-1 by a chemokine-triggered Rho signaling module. (2009) (1)
- Anti-CD3 mAb treatment cures PDL1-/-.NOD mice of diabetes but precipitates fatal myocarditis. (2011) (1)
- FLOW CYTOMETRIC ANALYSIS OF INTRACELLULAR CYTOKINE PRODUCTION IN RENAL TRANSPLANT RECIPIENTS (1999) (1)
- Introduction: Nephrology Hall of Fame for CJASN (2009) (1)
- Overview: future approaches to renal replacement and regeneration. (2004) (1)
- TIM-1 Plays a Crucial Role in the Expansion of Autopathogneic T-Cells and Regulation of Autoimmunity (2006) (1)
- LONG-TERM SURVIVAL OF CARDIAC ALLOGRAFTS INDUCED BY COSTIMULATORY BLOCKADE MAY REQUIRE INDIRECT RECOGNITION (1999) (1)
- The role of T-cell costimulatory pathways in ischemia—reperfusion injury (1998) (1)
- Tolerance is the achievable ‘Holy Grail’ in transplantation (2006) (1)
- INDUCTION OF MIXED HEMATOPOIETIC CHIMERISM AND TOLERANCE WITH SUBOPTIMAL RECIPIENT T CELL DEPLETION, 3GY TBI AND ANTI-CD154 OR CTLA4Ig: TOWARD A CLINICAL REGIMEN USEFUL FOR CADAVERIC DONORS (1999) (1)
- CD40 ligand-CD40 T cell costimulation pathway is required for host sensitization in the immune cascade leading to accelerated allograft rejection. (2001) (1)
- Chronic renal allograft dysfunction (CAD): new frontiers. Introduction. (2010) (1)
- This information is current as Memory T Cell-Mediated Rejection Critical , but Conditional , Role of OX 40 in LiLaurence (2006) (1)
- Chronic Rejection Rejection: Implications for Therapy of Allograft of FTY720 in a Transgenic Model of Novel Insights into the Mechanism of Action (2005) (1)
- Heart Allografts Are under Strict Regulation Rejection of Single Class II MHC-Disparate Alloreactive T Cell Responses and Acute and (2005) (1)
- Harnessing negative T‐cell costimulatory pathways to promote engraftment (2007) (1)
- Characterization of donor dendritic cells and enhancement of dc efflux with cc-chemokine ligand 21 : a novel strategy to prolong islet allograft survival (2007) (1)
- Sizzling Issues in Clinical Renal Transplantation (2010) (1)
- SUBSTANTIAL DONOR CHIMERISM AND TOLERANCE ACROSS A FULL MHC BARRIER WITHOUT HOST PRE-CONDITIONING (1999) (1)
- TNP-470, AN ANGIOGENESIS INHIBITOR, INTERRUPTS THE DEVELOPMENT OF GRAFT ARTERIOSCLEROSIS IN A RAT CARDIAC MODEL OF CHRONIC ALLOGRAFT REJECTION (1999) (1)
- CD4-targeted therapy induces "infectious" tolerance to cardiac allografts in sensitized rat recipients. (1997) (1)
- THE DIFFERENTIAL ROLE OF CD28‐B7 VERSUS CD40L‐CD40 IN REGULATING ALLOIMMUNE RESPONSES IN STAT 4 VERSUS STAT 6 GENE KNOCKOUT MICE.: Abstract# 1027 (2000) (1)
- DIFFERENTIAL MECHANISMS OF THE IMMUNOMODULATORY FUNCTIONS OF PEPTIDES DERIVED FROM CONSERVED REGIONS OF CLASS II MHC. (1999) (1)
- Response to letter to the editor: Immunophenotyping of SARS-CoV-2 and vaccine design (2022) (1)
- HLA-DR restricted binding of sleep inducing muramyl peptides to B cells of normals and narcoleptic subjects (1988) (1)
- Elevated levels of soluble HLA class I in the serum of multiple sclerosis patients (1994) (0)
- RAT CD28 SPECIFIC MONOCLONAL ANTIBODY: ITS POTENTIAL ROLE IN ACTIVATION INDUCED CELL DEATH AND PREVENTION OF ACUTE VASCULARIZED CARDIAC ALLOGRAFT REJECTION (1999) (0)
- INTERFERENCE WITH T CELL ACTIVATION SIGNAL ONE AND SIGNAL TWO WITH A COMBINATION OF ANTI-CD45RB AND ANTI-CD40L MONOCLONAL ANTIBODIES INDUCES LONG-TERM ISLET ALLOGRAFT SURVIVAL IN MICE (1998) (0)
- Activated protein C binds to A 50-55 KD receptor on human monocytes and inhibits cytokine production, mitogen responses and calcium signalling (1994) (0)
- GENETIC BASIS OF RESISTANCE TO TRANSPLANTATION TOLERANCE INDUCTION IN NOD MICE. (2006) (0)
- 430: Apoptosis Is an Effector Mechanism of Acute Cardiac Allograft Rejection: Involvement of Proteolytic Bcl-2 Degradation (2008) (0)
- Faculty Opinions recommendation of Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection. (2009) (0)
- in Alloimmune Responses CD28-independent Costimulation of T Cells (2001) (0)
- IL-17-Dependent Mechanism Intra-abdominal Sepsis by an T Cells Mediate Abscess Formation in + CD 4 (2003) (0)
- POST‐TRANSPLANT DE NOVO AUTOIMMUNITY CONTRIBUTES TO CARDIAC ALLOGRAFT REJECTION AND IT IS MEDIATED VIA INDIRECT PRESENTATION OF DONOR MHC PEPTIDES AND ORGAN‐SPECIFIC AUTOANTIGENS.: Abstract# 5 (2000) (0)
- CD40L COSTIMULATORY PATHWAY IS REQUIRED FOR HOST SENSITIZATION AND ITS BLOCKADE ABROGATES ACCELERATED GRAFT REJECTION IN PRESENSITIZED HOSTS.: Abstract# 2 (2000) (0)
- TNP-470, AN ANTI-ANGIOGENESIS AGENT, IS A POTENT INHIBITOR OF HUMAN CD4+ T CELL PROLIFERATION (1999) (0)
- O808 - Inhibition of the alloimmune response by synthetic peptides derived from highly conserved regions of class II MHC alpha chain (1996) (0)
- CHARACTERIZATION OF MHC ALLOPEPTIDE REACTIVE T CELL CLONES FROM HUMAN RENAL ALLOGRAFT RECIPIENTS (1998) (0)
- Faculty Opinions recommendation of Critical role of regulatory T cells in Th17-mediated minor antigen-disparate rejection. (2011) (0)
- HUMAN ALLOGRAFT REJECTION IS MEDIATED BY CD4+ T CELLS IN SCID MICE TRANSPLANTED WITH HUMAN THYMUS AND LIVER (THY/LIV SCID MICE).: Abstract# 719 (2000) (0)
- HIGH LEVELS OF STABLE MULTI-LINEAGE HEMATOPOIETIC CHIMERISM AND DONOR-SPECIFIC ALLOGENEIC SKIN GRAFT TOLERANCE WITH T-CELL COSTIMULATORY BLOCKADE (1998) (0)
- Faculty Opinions recommendation of The sphingosine 1-phosphate receptor agonist FTY720 potently inhibits regulatory T cell proliferation in vitro and in vivo. (2009) (0)
- SYNERGY BETWEEN SIGNAL 1 PLUS SIGNAL 2 BLOCKADE IN A STRINGENT MODEL OF ALLOGRAFT REJECTION.: Abstract# 998 (2000) (0)
- Renal Transplantation: Introduction (2007) (0)
- The role of B7 and CD2 family costimulatory molecules in natural killer cell function (2003) (0)
- OR.89. Notch Signaling Regulates Experimental Autoimmune Encephalomyelitis: Crosstalk Between Autoreactive T‐Cells and Astrocytes (2006) (0)
- Changes in Plasma Levels of VEGF-C and Endothelin-1 During the First Post-Transplant Year Are Predictive of Cardiac Allograft (2017) (0)
- INDIRECT ALLORECOGNITION OF DONOR CLASS II MHC PEPTIDES INDUCES ANTIBODY MEDIATED VASCULAR REJECTION OF CARDIAC ALLOGRAFTS (1998) (0)
- Oxide in Response to Self- and Alloantigens Nitric Oxide Synthase and Generate Nitric Thymic Dendritic Cells Express Inducible (2000) (0)
- The Role of CX3CR1 in dDC (Donor Dendritic Cells) Trafficking in Cardiac Transplant Model.: Abstract# B760 (2014) (0)
- BLOCKADE OF SIGNALS ONE AND TWO UTILIZING ANTI-CD45RB AND ANTI-CD40L SYNERGIZES TOLERANCE INDUCTION IN ISLET ALLOTRANSPLANTATION (1999) (0)
- HUMAN ENDOTHELIAL CELLS PROMOTE THE DIFFERENTIATION OF MONOCYTES INTO DENDRITIC CELLS AND FACILITATE INDIRECT ALLORECOGNITION (1999) (0)
- GENERATION AND CHARACTERIZATION OF CLASS II MHC ALLOPEPTIDE SPECIFIC Th1/Th2 CLONES FROM REJECTING AND TOLERANT ANIMALS IN AN EXPERIMNETAL RAT KIDNEY TRANSPLANT MODEL (1999) (0)
- SPECIFICITY AND FUNCTION OF CD4+ CD25+ REGULATORY T CELLS IN A NOVEL CD4+ TCR-TRANSGENIC MODEL OF ALLOIMMUNITY (2004) (0)
- Faculty Opinions recommendation of Intracellular MHC class II controls regulatory tolerance to allogeneic transplants. (2011) (0)
- Alloreactive T Cell Clone Size + Alloimmunity : Cytokines , CTLA-4 , CD 25 Physiological Mechanisms of Regulating (2002) (0)
- Effect of targeting BTLA-HVEM co-inhibitory pathway in partial MHC-mismatched cardiac grafts (2006) (0)
- Allografts After Costimulatory Blockade Long-Term Survival of Murine Cardiac Expression Is Required to Achieve Cutting Edge: Recipient MHC Class II (2001) (0)
- Antibodies to a homologue of MDR-P-glycoprotein on chromosome 7p15-21 and Uses Thereof (2001) (0)
- Acquired tolerance to EAE by intrathymic injection of MBP peptides: Role of thymic dendritic cells (1994) (0)
- The role of CD25+regulatory cells in restoring tolerance in autoimmune anti-GBM (Goodpasture's) disease. (2002) (0)
- TARGETING CHEMOKINE RECEPTORS CXCR3 AND CCR5 REDUCES RENAL ISCHEMIC INJURIES (2004) (0)
- Expansion and characterization of CD4(+)CD25(+) regulatory T-cells from human renal transplant recipients. (2003) (0)
- AN INTACT PD1/PDL1 PATHWAY IS REQUIRED FOR INDUCTION OF TRANSPLANTATION TOLERANCE BY CD28-B7 OR CD154-CD40 COSTIMULATORY BLOCKADE. (2006) (0)
- ABCB 5 Identifies Immunoregulatory Dermal Cells Graphical Abstract Highlights (2018) (0)
- IN VIVO MECHANISMS OF TRANSPLANTATION TOLERANCE BY SIGNAL ONE BLOCKADE WITH &agr;‐CD45RB: ROLE OF CTLA4 NEGATIVE T CELL COSTIMULATORY PATHWAY.: Abstract# 356 (2000) (0)
- Methods for immunomodulation (2004) (0)
- ORGANIZATION, STRUCTURE AND SEQUENCE OF THE RAT TCR BETA GENOMIC LOCI (1999) (0)
- Comprar Chronic Kidney Disease, Dialysis, and Transplantation, 3rd Edition | Mohamed Sayegh | 9781437709872 | Saunders (2010) (0)
- Chapter 31 – Transplantation Immunobiology (2005) (0)
- Induced costimulatory molecule-B7h costimulatory pathway in alloimmune regulation (2005) (0)
- LATE BLOCKADE OF B7-1 COSTIMULATION INTERRUPTS THE DEVELOPMENT OF CHRONIC REJECTION IN A RAT MODEL OF CARDIAC TRANSPLANTATION. (1998) (0)
- Faculty Opinions recommendation of T cell allorecognition via molecular mimicry. (2010) (0)
- CD28: beyond just T-cell costimulation (2007) (0)
- Faculty Opinions recommendation of TLR signals promote IL-6/IL-17-dependent transplant rejection. (2009) (0)
- The T Cell Response to Transplantation Antigens (2012) (0)
- Comprar Core Concepts in Renal Transplantation | Chandraker, Anil | 9781461400073 | Springer (2011) (0)
- RETENTION OF REGULATORY ACTIVITY IN CD4+CD25+ T-CELLS ISOLATED FROM RENAL TRANSPLANT RECIPIENTS FOLLOWING EX-VIVO EXPANSION (2004) (0)
- Faculty Opinions recommendation of Primed CD8(+) T-cell responses to allogeneic endothelial cells are controlled by local complement activation. (2009) (0)
- EXPLORATION OF THE ROLE OF B7H4 IN CHRONIC ALLOGRAFT VASCULOPATHY: 1529 (2008) (0)
- Alloreactive T Cell Clone Size Cells, and the + CTLA-4, CD25 Regulating Alloimmunity: Cytokines, Physiological Mechanisms of (2010) (0)
- The role of the novel gene, T-bet, in allograft rejection and tolerance. (2003) (0)
- Immunogenicity of class II MHC allopeptides in vivo (1992) (0)
- Survival of Allogeneic Heart Transplants Response to Cardiac Myosin Can Prolong Modulation of Tissue-Specific Immune (2002) (0)
- VivoChemokine/Chemokine Receptor Function In Allograft Rejection: Tissue Specificity of Differential Role of CCR2 in Islet and Heart (2003) (0)
- Overcome It T Cell Depletion and Approaches to Accelerated Memory Cell Homeostasis during (2006) (0)
- DETERMINATION OF THE ALLOREACTIVE T CELL FREQUENCY IN VIVO: WHAT YOU GET DEPENDS UPON WHAT YOU MEASURE.: Abstract# 151 (2000) (0)
- BLOCKING OX40 COSTIMULATION OR MTOR IS REQUIRED TO PREVENT CD8+ MEDIATED REJECTION (2004) (0)
- Regulation of autoimmune diabetes in NOD mice: Critical role for the PD-1 : PD-L1 costimulatory pathway. (2002) (0)
- Th1-specific transcription factor T-bet-deficiency - a new model of acute and accelerated chronic vascular allograft rejection (2005) (0)
- Presidential & Awards Session (2011) (0)
- ROLE OF CD4 AND CD8 T CELLS IN VASCULARIZED CARDIAC ALLOGRAFT REJECTION MEDIATED BY DIRECT AND INDIRECT ALLORECOGNITION.: Abstract# 498 Poster Board #‐Session: P138‐II (2000) (0)
- CONCURRENT SESSION 4: GENERATION AND FUNCTION OF TREGS (2006) (0)
- INDUCTION OF TOLEROGENIC DENDRITIC CELLS BY TARGETING CHEMOKINE RECEPTOR CCR2 IN ISLET CELL TRANSPLANTATION. (2006) (0)
- Cells in Fetomaternal Tolerance A Link between PDL1 and T Regulatory (0)
- Experimental Autoimmune Type 1 Diabetes Marrow-Derived Mesenchymal Stem Cells in Immunomodulatory Function of Bone (2009) (0)
- Agonistic and antagonistic interactions between CTLA4Ig and donor alloantigens in sensitized rat recipients of cardiac allografts. (1998) (0)
- MHC ALLOPEPTIDE REACTIVE T CELL CLONES GENERATED FROM HUMAN RENAL ALLOGRAFT RECIPIENTS: INDIRECT ALLORECOGNITION IN LONG TERM ENGRAFTMENT (1999) (0)
- Following Islet Transplantation by Gene Prevention of Recurrent Type 1 Diabetes Induction of Robust Diabetes Resistance and Donnarumma (2007) (0)
- 793. Induction of Molecular Chimerism in NOD Mice Is Resistant to the Occurrence of Type I Diabetes Induced by Blockade of the Programmed Death-1 Pathway (2006) (0)
- COSTIMULATION IN TRANS CAN MEDIATE ACUTE REJECTION OF CARDIAC ALLOGRAFTS.: Abstract# 1164 (2000) (0)
- Programmed Death-1 Inhibitory Pathway Regulation of Postsurgical Fibrosis by the and (2004) (0)
- CTLA4Ig INDUCES REGULATORY T CELLS THAT MEDIATE LINKED REGULATION OF ALLOGENEIC T CELL RESPONSES.: Abstract# 1101 (2000) (0)
- Xenogeneic Human Anti-Porcine T Cell Prevents Costimulation of Allogeneic Porcine Blockade of CD 28B 7 , But Not CD 40-CD 154 , (2000) (0)
- THE ROLE OF CTLA4-MEDIATED NEGATIVE SIGNALS AND CELL SURVIVAL IN TOLERANCE INDUCTION BY BLOCKADE OF B7:CD28 AND CD40:CD40L (CD154). (1999) (0)
- Faculty Opinions recommendation of TGF-beta-dependent suppressive function of Tregs requires wild-type levels of CD18 in a mouse model of psoriasis. (2008) (0)
- Diabetes mellitus - basic research (2009) (0)
- Novel Strategies Using MHC Peptides (2001) (0)
- CD4+ CD25+ regulatory T cells mediate antigen-specificity in a novel TCR transgenic model of alloimmunity (2005) (0)
- In Vitro and In Vivo Studies of IgG-derived Treg Epitopes (Tregitopes): A Promising New Tool for Tolerance Induction and Treatment of Autoimmunity (2012) (0)
- AnergyApoptosis of Thymocytes and Peripheral T Cell Vivo: Intrathymic Injection of Antigen Induces Mechanisms of Acquired Thymic Tolerance In (1998) (0)
- Invitation for Commentary (2006) (0)
- EARLY DELETION AFTER BONE MARROW TRANSPLANTATION WITH COSTIMULATORY BLOCKADE IS FAS-DEPENDENT AND IS PREVENTED BY BCL-XL OVEREXPRESSION (1999) (0)
- INDUCTION OF APOPTOSIS BY A MHC CLASS II DERIVED PEPTIDE THROUGH A CASPASE INDEPENDENT PATHWAY.: Abstract# 880 Poster Board #‐Session: P137‐III (2000) (0)
- Inhibiting Alloimmune Responses In Vivo Ligand 1/B7.1 Pathway Is Functional in The Novel Costimulatory Programmed Death (2011) (0)
- Acute Cardiac Allograft Rejection: Involvement of Apoptotic Cell Death and Proteolytic Bcl-2 Degradation (1999) (0)
- Faculty Opinions recommendation of Development and characterization of IL-21-producing CD4+ T cells. (2008) (0)
- MODULATORS OF P-GLYCOPROTEIN-MEDIATED TRANSMEMBRANE TRANSPORT INHIBIT T-CELL PROLIFERATION IN VITRO (1999) (0)
- P‐GLYCOPROTEIN FUNCTION IN HUMAN ALLOIMMUNE INTERACTIONS.: Abstract# 78 (2000) (0)
- Abstract 540: Correlation of Improved Cholesterol Efflux Capacity of High Density Lipoprotein With Survival and Allograft Vasculopathy in Cardiac Transplant Recipients (2015) (0)
- Allograft Acceptance by TLR Ligands Mechanisms Underlying Blockade of (2008) (0)
- DO HUMAN ENDOTHELIAL CELLS UTILIZE THE CD28/B7 PATHWAY TO COSTIMULATE CD4+ T CELL ACTIVATION? (1998) (0)
- Prolongation of heart allograft survival by modulating of tissue-specific response requires low frequency of alloreactive T cells (2002) (0)
- AST Officers, Committees (2003) (0)
- Introduction: Conflict Nephrology Revisited. (2020) (0)
- For a homologous the human, responsible for multiple resistance, p-glycoprotein on chromosome 7p15-21 coding gen and uses therefor (2001) (0)
- T CELL COSTIMULATORY BLOCKADE SUPPRESSES INDIRECT BETTER THAN DIRECT ALLOIMMUNE RESPONSES IN VIVO (1998) (0)
- Moving points in pediatric nephrology and transplantation (1997) (0)
- Introducing Presse Rénale (2007) (0)
- INDUCTION OF TOLERANCE BY SIGNAL ONE BLOCKADE WITH ANTI-CD45RB REQUIRES NEGATIVE SIGNALING THROUGH CTLA-4. (1999) (0)
- Renal Transplantation Incidence of cancers in people with HIV/ AIDS compared with immunosuppressed transplant recipients: A meta-analysis. (2007) (0)
- Su.26. PDL1 Regulates Autoimmunity By Limiting Expansion of Autoreactive Th1 Cells and Mediates Resistance to Diabetes in Nod Mice (2006) (0)
- Diff erential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and eff ector function (2007) (0)
- Abstract 512: Fibroblasts Associated with Cardiac Fibrosis Carry Endothelial Imprint: Implication for Endothelial to Mesenchymal Transition (2006) (0)
- CellsProtection of Human Mesenchymal Stem The Novel Role of SERPINB9 in Cytotoxic (2011) (0)
- Erratum: Promotion of altruistic donation (Transplantation (2009) (847)) (2009) (0)
- New therapies Maintenance pharmacological immunosuppressive strategies in renal transplantation (2003) (0)
- EXPLORATION OF THE ROLE OF THE NOVEL B7 FAMILY MEMBER B7H4 IN CHRONIC REJECTION: 1531 (2008) (0)
- TRANSPLANT SPECIFIC TOLERANCE AFTER TRANSFER OF ALLOPEPTIDE SPECIFIC TH2-, BUT NOT OF TH1 CELL CLONES, IS ASSOCIATED WITH GATA-3 EXPRESSION IN THE GRAFT AND REGULATION OF THE IMMUNE RESPONSE (2004) (0)
- CD28:B7 BLOCKADE PREVENTS TRANSPLANT VASCULOPÁTHY AND MONONUCLEAR CELL INFILTRATION IN A FULLY ALLOGENEIC CARDIAC TRANSPLANT MODEL (1998) (0)
- Minimisation of immunosuppression in transplantation – Authors' reply (2007) (0)
- NON‐IMMUNOLOGIC MECHANISMS OF ISLET ALLOGRAFT DYSFUNCTION: EFFECT OF DIABETES CONTROL ON ISLET ALLOGRAFT DYSFUNCTION.: Abstract# 370 Poster Board #‐Session: P10‐II (2000) (0)
- IMMUNOMODULATORY FUNCTION OF LOW MOLECULAR WEIGHT HYALURONATE DELAYS ALLOGRAFT REJECTION AND IMPROVES SURVIVAL IN A RAT ACUTE KIDNEY REJECTION MODEL. (1998) (0)
- CORRECTION (2003) (0)
- THE ROLE OF CTLA4 NEGATIVE SIGNALING PATHWAY IN THE INDUCTION OF ACQUIRED THYMIC TOLERANCE IN VIVO (1998) (0)
- Multicenter Study to Determine Up to 5 Year Clinical Outcome of Heart Transplant Recipient Receiving Rituximab Versus Placebo Outcomes in Subjects Previously Randomized in the CTOT-11 Study (2018) (0)
- Immunobiology of Allograft Destruction (1996) (0)
- Autoimmune Disease Model Tolerance in a Clinically Relevant in the Initiation and Maintenance of Acquired Thymic Tolerance : Role of CTLA 4 and (1998) (0)
- INDUCTION OF DONOR SPECIFIC ACQUIRED THYMIC TOLERANCE BY INTRATHYMIC INOCULATION OF A SINGLE SYNTHETIC ALLO-MHC CLASS I PEPTIDE [RT1.Au] (1998) (0)
- MECHANISMS OF ISLET ALLOGRAFT REJECTION: ROLE OF AUTOIMMUNITY AND EFFECT OF T CELL COSTIMULATORY BLOCKADE.: Abstract# 898 Poster Board #‐Session: P155‐III (2000) (0)
- through Enhanced CTLA-4 Expression Cutting Edge: Transplantation Tolerance (2003) (0)
- PRE-TRANSPLANT DONOR-SPECIFC TRANSFUSIONS COMBINED WITH CYCLOSPORINE BUT NOT WITH RAPAMYCIN INDUCE TOLERANCE TO MHC CLASS I-MISMATCHED CARDIAC ALLOGRAFTS IN MINIATURE SWINE (2004) (0)
- Faculty Opinions recommendation of Allo-HLA reactivity of virus-specific memory T cells is common. (2010) (0)
- Tolerance: Is it time to Move to the Clinic? (2001) (0)
- CHALLENGING CURRENT DOGMAS: DONOR BONE MARROW T CELLS ARE REQUIRED FOR INDUCTION OF DURABLE TOLERANCE TO SKIN ALLOGRAFTS BY MIXED ALLOGENEIC CHIMERISM. (2006) (0)
- 542 Incidence of Coronary Artery Vasculopathy Has Decreased with Modern Immunosuppression: Insights from Clinical Trials in Organ Transplantation (2011) (0)
- Suppressor cells generated between family members exhibit major histocompatibility complex restriction (1988) (0)
- A gene encoding a homologue of human P-glycoprotein multidrug-resistant in chromosome 7p15-21 and uses thereof (2001) (0)
- TolerancePathway and Th17 in Fetomaternal The Link between the PDL1 Costimulatory (2011) (0)
- Therapeutic strategies targeted at CD4+ cells obviate accelerated rejection of cardiac allografts in sensitized rats. (1991) (0)
- RENAL TRANSPLANTATION (1996) (0)
- I m m u n o s u p p ressive strategies in transplantation (1999) (0)
- A SIGNALING CD28 ANTIBODY PROLONGS SURVIVAL AND PRESERVES RENAL ALLOGRAFT STRUCTURE AND FUNCTION IN A RAT MODEL OF CHRONIC REJECTION.: Abstract# 1169 (2000) (0)
- Rivers to Cross Clinical Transplantation Tolerance : Many (2007) (0)
- Faculty Opinions recommendation of Mesenchymal stem cells prevent the rejection of fully allogenic islet grafts by the immunosuppressive activity of matrix metalloproteinase-2 and -9. (2009) (0)
- Faculty Opinions recommendation of The chemokine receptor Cxcr3 is not essential for acute cardiac allograft rejection in mice and rats. (2008) (0)
- Chapter 32 – Transplantation Immunobiology (2010) (0)
- Mechanisms of Acquired Thymic Tolerance in Experimental Autoimmtme Encephalomyelitis: Thymic Dendritic-enriched Cells Induce Specific Peripheral T Cell Unresponsiveness In Vivo By Samia J. Khoury,* Lorenzo Gallon, Wanjun Chen,* (1995) (0)
- B7‐1 IS THE DOMINANT LIGAND FOR CTLA‐4 DOWN REGULATION OF ALLOIMMUNE RESPONSES IN VIVO.: Abstract# 1157 (2000) (0)
- Functions of the PD-1: PD-L1 costimulatory pathway in physiologic regulation of alloimmune responses in vivo (2003) (0)
- OR.107. TIM-1 Plays a Crucial Role in the Expansion of Autopathogneic T-Cells and Regulation of Autoimmunity [abstract only] (2006) (0)
- DISTINCT TOLERANCE PATHWAYS IN SENSITIZED GRAFT RECIPIENTS (1998) (0)
- Cell-Mediated Rejection T + and CD 8 + Requirements for CD 4 Different Costimulatory and Growth Factor (2004) (0)
- Post-transplantation hypertension. (2000) (0)
- ROLES OF DONOR-DERIVED SELECTINS IN THE DEVELOPMENT OF BOTH ACUTE REJECTION AND GRAFT ARTERIOSCLEROSIS. (2006) (0)
- PASSIVE T CELL DEATH IS NOT REQUIRED FOR INDUCTION OF TRANSPLANTATION TOLERANCE TO MINOR HISTOCOMPATIBILITY ANTIGENS MISMATCHED ALLOGRAFTS.: Abstract# 134 (2000) (0)
- Differential Gene Expression Identifies Novel Markers of Myelin-Specific Murine Memory CD4+ T Cells (2007) (0)
- Cell Death Activation-Induced Cell Death and Passive Blockade Has Features of Both Transplantation with Costimulatory Peripheral Deletion After Bone Marrow (2001) (0)
- Regulatory phenotype is enriched in the CD25 'high' sub-population of CD4(+)CD25(+) cells expanded from renal transplant recipients. (2004) (0)
- PREVENTION OF GRAFT ARTERIOSCLEROSIS MEDIATED BY INDIRECT ALLORECOGNITION USING A SIGNALING CD28 ANTIBODY.: Abstract# 1168 (2000) (0)
- This information is current as via Programmed Death Ligand 1 Cells and Prolongs Islet Allograft Survival Mobilizes Autologous Hematopoietic Stem CXCL12 Axis - Targeting the CXCR4 (2012) (0)
- Faculty Opinions recommendation of Contribution of naïve and memory T-cell populations to the human alloimmune response. (2009) (0)
- Understanding how Tregs are regulated: therapeutic implications. (2009) (0)
- ALLOGENEIC ENDOTHELIUM INDUCES B7-2 EXPRESSION IN TRANSMIGRATING LEUKOCYTES. (1998) (0)
- Generation of regulatory CD8(+) T cells by ICOS-B7h signal blockade in vivo. (2004) (0)
- REPLY: DISCREPANCY IN PEPTIDES SERIOUSLY DAMAGES STUDY (1997) (0)
- POST‐TRANSPLANT AUTOIMMUNITY TO CARDIAC MYOSIN CAN BE DETECTED DURING INITIAL STAGES OF CHRONIC REJECTION OF CARDIAC ALLOGRAFTS.: Abstract# 4 (2000) (0)
- Faculty Opinions recommendation of Foxp3+ T cells induce perforin-dependent dendritic cell death in tumor-draining lymph nodes. (2010) (0)
- THE TH1/TH2 PARADIGM REVISITED: REGULATORY FUNCTIONS OF ALLOREACTIVE TH2 CLONES IN VIVO.: Abstract# 144 (2000) (0)
- EFFECTS OF SELECTIVE CD28:B7-1 BLOCKADE IN ACUTE CARDIAC ALLOGRAFT REJECTION (1998) (0)
- NEW INSIGHTS INTO ICOS-B7h PATHWAY IN ALLOIMMUNE RESPONSE (2004) (0)
- Tolerance induction for islet transplantation in stringent models. (2003) (0)
- Coichicine Interferes with L-Selectin and Leukocyte Function-Associated Antigen-i Expression on Human I Lymphocytes a nd Inhibits I Cell (1996) (0)
- INDIRECT RECOGNITION OF DONOR CLASS I PEPTIDES INDUCES AND ACCELERATES CARDIAC ALLOGRAFT VASCULOPATHY IN THE MINIATURE SWINE.: Abstract# 1004 (2000) (0)
- DICHOTOMY OF PD-L1 AND PD-L2 PATHWAYS IN NEGATIVELY REGULATING ALLOREACTIVE CD4+ AND CD8+ T CELLS (2004) (0)
- Blockade of T-cell costimulatory pathways protects from experimental autoimmune encephalomyelitis in Th2 deficient mice (2002) (0)
- Responses and Xenogeneic Human Anti-Porcine T Cell Prevents Costimulation of Allogeneic Porcine Blockade of CD28-B7, But Not CD40-CD154, (2000) (0)
- a Reciprocal Cytokine Environment In Vivo Defining Th1 and Th2 Immune Responses in (2013) (0)
- Medical management of kidney transplantation (2005) (0)
- Correction (1976) (0)
- 326: Novel Role of the Tim-4 Molecule in Alloimmunity (2010) (0)
- Novel and conventional costimulatory blockades for tolerance induction in cardiac allotransplanation (2003) (0)
- Visualization of alloreactive CD4 T cell responses and tolerance induction in vivo (2003) (0)
- 936-85 Intrathymic Injection of Donor Splenocytes Prolongs Rat Cardiac Allograft Survival but Does not Inhibit Graft Arteriosclerosis (1995) (0)
- CJASN: Passing the Torch (2010) (0)
- Function in Alloimmunity Regulatory T Cell + CD25+ Specificity of CD4 (0)
- CJASN Matures to a Monthly Journal (2009) (0)
- Renal Transplantation: What's New? (2008) (0)
- Blockade In Vivo Regulatory T Cell Induced by ICOS-B 7 h + PD 1 + A Novel Alloantigen-Specific CD 8 Sayegh and (2007) (0)
- Chronic rejection from bedside to bench: role of T cells. (1997) (0)
- 29: Expansion of CD4+CD25+FoxP3+ Regulatory T Lymphocytes with Low-Dose Anti-Thymocyte Globulin Leads to Prolonged Survival of Cardiac Allografts but Not Tolerance (2009) (0)
- Erratum: (The Journal of Experimemal Medicine (July 7, 2003) 198:1 (71-78)) (2003) (0)
- T Cells by Skin Grafts Via Direct + CD 8 ofPathway Is Required for Host Sensitization The CD 154-CD 40 T Cell Costimulation (2002) (0)
- CD8+ T Cells by Skin Grafts Via Direct of Pathway Is Required for Host Sensitization The CD154-CD40 T Cell Costimulation (2013) (0)
- Human Tolerance Maternal Acceptance of the Fetus: True (2013) (0)
- Activation In Vitro Inhibits Human Alloimmune T Cell Specific MDR1 P-Glycoprotein Blockade (2013) (0)
- CD 154-Independent Rejection Critical Role of OX 40 in CD 28 and Sayegh and (2004) (0)
- Tolerance in Stringent Transplant Models Promotes Long Term Engraftment and Synergizes with CD40 Ligand Blockade and Targeting Signal 1 Through CD45RB (2000) (0)
- T-cell response to cardiac myosin persists in the absence of an alloimmune response in recipients with chronic cardiac allograft rejection1 (2002) (0)
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What Schools Are Affiliated With Mohamed Hassan Sayegh?
Mohamed Hassan Sayegh is affiliated with the following schools: