Moosa Mohammadi

Q: What Schools Are Affiliated With Moosa Mohammadi

Moosa Mohammadi is affiliated with the following schools: New York University, Queensland University of Technology, University of California, Berkeley, Sharif University of Technology, Stanford University

Moosa Mohammadi's AcademicInfluence.com Rankings

Moosa Mohammadi

Computer Science

#8315

World Rank

#8741

Historical Rank

Computational Linguistics

#1828

World Rank

#1847

Historical Rank

Machine Learning

#3375

World Rank

#3415

Historical Rank

Artificial Intelligence

#3673

World Rank

#3725

Historical Rank

computer-science Degrees

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Computer Science

Moosa Mohammadi's Degrees

PhD Computer Science University of California, Berkeley
Masters Computer Science University of California, Berkeley
Bachelors Computer Science Sharif University of Technology

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Moosa Mohammadi's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The FGF family: biology, pathophysiology and therapy (2009) (1595)
Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21. (2007) (1378)
Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors. (1997) (1137)
Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization. (2000) (1107)
The parathyroid is a target organ for FGF23 in rats. (2007) (929)
Catalytic specificity of protein-tyrosine kinases is critical for selective signalling (1995) (916)
Structural basis for fibroblast growth factor receptor activation. (2005) (717)
Tissue-specific Expression of βKlotho and Fibroblast Growth Factor (FGF) Receptor Isoforms Determines Metabolic Activity of FGF19 and FGF21* (2007) (657)
FGF21 induces PGC-1α and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response (2009) (637)
Receptor Specificity of the Fibroblast Growth Factor Family (2006) (631)
The function of GRB2 in linking the insulin receptor to Ras signaling pathways. (1993) (601)
Research resource: Comprehensive expression atlas of the fibroblast growth factor system in adult mouse. (2010) (599)
Structural Basis for FGF Receptor Dimerization and Activation (1999) (581)
βKlotho is required for metabolic activity of fibroblast growth factor 21 (2007) (542)
SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors. (2000) (505)
Molecular Insights into the Klotho-Dependent, Endocrine Mode of Action of Fibroblast Growth Factor 19 Subfamily Members (2007) (493)
Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases (1991) (487)
Crystal structure of an angiogenesis inhibitor bound to the FGF receptor tyrosine kinase domain (1998) (474)
Circulating FGF21 Is Liver Derived and Enhances Glucose Uptake During Refeeding and Overfeeding (2014) (466)
Exploring mechanisms of FGF signalling through the lens of structural biology (2013) (445)
A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1 (1991) (439)
Point mutation in FGF receptor eliminates phosphatidylinositol hydrolysis without affecting mitogenesis (1992) (416)
Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction (1996) (400)
Crystal Structures of Two FGF-FGFR Complexes Reveal the Determinants of Ligand-Receptor Specificity (2000) (387)
FGF23 decreases renal NaPi-2a and NaPi-2c expression and induces hypophosphatemia in vivo predominantly via FGF receptor 1. (2009) (368)
Inhibition of growth hormone signaling by the fasting-induced hormone FGF21. (2008) (367)
A homozygous missense mutation in human KLOTHO causes severe tumoral calcinosis. (2007) (362)
Structure of the FGF Receptor Tyrosine Kinase Domain Reveals a Novel Autoinhibitory Mechanism (1996) (360)
Digenic mutations account for variable phenotypes in idiopathic hypogonadotropic hypogonadism. (2007) (359)
Decreased FGF8 signaling causes deficiency of gonadotropin-releasing hormone in humans and mice. (2008) (357)
Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation (2009) (327)
Fibroblast growth factor 21 promotes bone loss by potentiating the effects of peroxisome proliferator-activated receptor γ (2012) (322)
Frequent activating FGFR2 mutations in endometrial carcinomas parallel germline mutations associated with craniosynostosis and skeletal dysplasia syndromes (2007) (315)
Autoregulatory Mechanisms in Protein-tyrosine Kinases* (1998) (311)
αKlotho is a Non-Enzymatic Molecular Scaffold for FGF23 Hormone Signaling (2018) (282)
SH2 domains prevent tyrosine dephosphorylation of the EGF receptor: identification of Tyr992 as the high‐affinity binding site for SH2 domains of phospholipase C gamma. (1992) (276)
Impaired FGF signaling contributes to cleft lip and palate (2007) (275)
The tyrosine phosphorylated carboxyterminus of the EGF receptor is a binding site for GAP and PLC‐gamma. (1990) (246)
Signal transduction by the α6β4 integrin: distinct β4 subunit sites mediate recruitment of Shc/Grb2 and association with the cytoskeleton of hemidesmosomes (1995) (246)
In vivo genetic evidence for klotho‐dependent, fibroblast growth factor 23 (Fgf23) ‐mediated regulation of systemic phosphate homeostasis (2009) (245)
A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. (2007) (244)
Fibroblast Growth Factor (FGF) Homologous Factors Share Structural but Not Functional Homology with FGFs* (2003) (244)
Mutations in fibroblast growth factor receptor 1 cause both Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism. (2006) (228)
Tyr phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate the pyruvate dehydrogenase complex. (2014) (220)
Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism. (2013) (213)
Analysis of the biochemical mechanisms for the endocrine actions of fibroblast growth factor-23. (2005) (208)
Structural basis for fibroblast growth factor receptor 2 activation in Apert syndrome (2001) (207)
Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer (2014) (197)
Molecular mechanisms of fibroblast growth factor signaling in physiology and pathology. (2013) (196)
Structural basis by which alternative splicing modulates the organizer activity of FGF8 in the brain. (2006) (194)
Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity. (2004) (193)
Mutations in fibroblast growth factor receptor 1 cause Kallmann syndrome with a wide spectrum of reproductive phenotypes (2006) (182)
Kinetic model for FGF, FGFR, and proteoglycan signal transduction complex assembly. (2004) (180)
Differential Interactions of FGFs with Heparan Sulfate Control Gradient Formation and Branching Morphogenesis (2009) (180)
Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptors (2003) (176)
FGF23 promotes renal calcium reabsorption through the TRPV5 channel (2014) (173)
FGF23 acts directly on renal proximal tubules to induce phosphaturia through activation of the ERK1/2–SGK1 signaling pathway (2012) (171)
Biochemical analysis of pathogenic ligand-dependent FGFR2 mutations suggests distinct pathophysiological mechanisms for craniofacial and limb abnormalities. (2004) (153)
A protein canyon in the FGF-FGF receptor dimer selects from an à la carte menu of heparan sulfate motifs. (2005) (151)
Arterial Klotho Expression and FGF23 Effects on Vascular Calcification and Function (2013) (141)
Parathyroid-Specific Deletion of Klotho Unravels a Novel Calcineurin-Dependent FGF23 Signaling Pathway That Regulates PTH Secretion (2013) (141)
Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors (2014) (136)
Genetic overlap in Kallmann syndrome, combined pituitary hormone deficiency, and septo-optic dysplasia. (2012) (132)
FGF-23–Klotho signaling stimulates proliferation and prevents vitamin D–induced apoptosis (2008) (132)
Proline to arginine mutations in FGF receptors 1 and 3 result in Pfeiffer and Muenke craniosynostosis syndromes through enhancement of FGF binding affinity. (2003) (129)
Loss-of-Function Fibroblast Growth Factor Receptor-2 Mutations in Melanoma (2009) (123)
The demonstration of αKlotho deficiency in human chronic kidney disease with a novel synthetic antibody. (2015) (123)
Internalization of fibroblast growth factor receptor is inhibited by a point mutation at tyrosine 766. (1994) (122)
Crystal Structure of a Fibroblast Growth Factor Homologous Factor (FHF) Defines a Conserved Surface on FHFs for Binding and Modulation of Voltage-gated Sodium Channels* (2009) (118)
Pregnane X receptor activation induces FGF19-dependent tumor aggressiveness in humans and mice. (2011) (116)
The N550K/H mutations in FGFR2 confer differential resistance to PD173074, dovitinib, and ponatinib ATP-competitive inhibitors. (2013) (114)
Reduced Activation of RAF-1 and MAP Kinase by a Fibroblast Growth Factor Receptor Mutant Deficient in Stimulation of Phosphatidylinositol Hydrolysis (*) (1995) (103)
A homozygous missense mutation in human KLOTHO causes severe tumoral calcinosis. (2007) (99)
Impaired fibroblast growth factor receptor 1 signaling as a cause of normosmic idiopathic hypogonadotropic hypogonadism. (2009) (94)
Fibroblast growth factor 1 ameliorates diabetic nephropathy by an anti-inflammatory mechanism. (2018) (94)
Point mutation in the fibroblast growth factor receptor eliminates phosphatidylinositol hydrolysis without affecting neuronal differentiation of PC12 cells. (1994) (92)
Regulation of serum 1,25(OH)2 vitamin D3 levels by fibroblast growth factor 23 is mediated by FGF receptors 3 and 4. (2011) (86)
Conversion of a Paracrine Fibroblast Growth Factor into an Endocrine Fibroblast Growth Factor* (2012) (82)
Signal transduction by the alpha 6 beta 4 integrin: distinct beta 4 subunit sites mediate recruitment of Shc/Grb2 and association with the cytoskeleton of hemidesmosomes. (1995) (82)
A Single Amino Acid Substitution in the Activation Loop Defines the Decoy Characteristic of VEGFR-1/FLT-1* (2006) (81)
Understanding the Molecular Basis of Apert Syndrome (2005) (80)
Nonsense mutations in FGF8 gene causing different degrees of human gonadotropin-releasing deficiency. (2010) (79)
Grb2, a Double-Edged Sword of Receptor Tyrosine Kinase Signaling (2012) (79)
Inhibition of fibroblast growth factor 23 (FGF23) signaling rescues renal anemia (2018) (75)
The structural biology of the FGF19 subfamily. (2012) (73)
FGF21 mediates alcohol-induced adipose tissue lipolysis by activation of systemic release of catecholamine in mice[S] (2015) (71)
Crystal Structure of Fibroblast Growth Factor 9 Reveals Regions Implicated in Dimerization and Autoinhibition* (2001) (69)
The alternatively spliced acid box region plays a key role in FGF receptor autoinhibition. (2012) (69)
Identification of Receptor and Heparin Binding Sites in Fibroblast Growth Factor 4 by Structure-Based Mutagenesis (2001) (69)
Analysis of Mutations in Fibroblast Growth Factor (FGF) and a Pathogenic Mutation in FGF Receptor (FGFR) Provides Direct Evidence for the Symmetric Two-End Model for FGFR Dimerization (2005) (67)
Klotho Coreceptors Inhibit Signaling by Paracrine Fibroblast Growth Factor 8 Subfamily Ligands (2012) (67)
A crystallographic snapshot of tyrosine trans-phosphorylation in action (2008) (65)
Compositional analysis of heparin/heparan sulfate interacting with fibroblast growth factor.fibroblast growth factor receptor complexes. (2009) (63)
KLB, encoding β‐Klotho, is mutated in patients with congenital hypogonadotropic hypogonadism (2017) (63)
Uncoupling the Mitogenic and Metabolic Functions of FGF1 by Tuning FGF1-FGF Receptor Dimer Stability. (2017) (59)
Fibroblast growth factor 21 deficiency exacerbates chronic alcohol-induced hepatic steatosis and injury (2016) (59)
Aggregation-induced activation of the epidermal growth factor receptor protein tyrosine kinase. (1993) (56)
Congenital hypogonadotropic hypogonadism with split hand/foot malformation: a clinical entity with a high frequency of FGFR1 mutations (2014) (55)
Structural Basis for Activation of Fibroblast Growth Factor Signaling by Sucrose Octasulfate (2002) (51)
FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis (2020) (51)
Homodimerization Controls the Fibroblast Growth Factor 9 Subfamily's Receptor Binding and Heparan Sulfate-Dependent Diffusion in the Extracellular Matrix (2009) (47)
Identification of Phosphopeptides by MALDI Q-TOF MS in Positive and Negative Ion Modes after Methyl Esterification*S (2005) (47)
A threshold model for receptor tyrosine kinase signaling specificity and cell fate determination (2018) (46)
Fibroblast growth factor signalling in osteoarthritis and cartilage repair (2020) (44)
Structural mimicry of a-loop tyrosine phosphorylation by a pathogenic FGF receptor 3 mutation. (2013) (43)
Decreased FGF 8 signaling causes deficiency of gonadotropin-releasing hormone in humans and mice (2008) (42)
Two FGF Receptor Kinase Molecules Act in Concert to Recruit and Transphosphorylate Phospholipase Cγ. (2016) (42)
DFG-out Mode of Inhibition by an Irreversible Type-1 Inhibitor Capable of Overcoming Gate-Keeper Mutations in FGF Receptors (2014) (41)
Plasticity in Interactions of Fibroblast Growth Factor 1 (FGF1) N Terminus with FGF Receptors Underlies Promiscuity of FGF1* (2011) (38)
β-Klotho deficiency protects against obesity through a crosstalk between liver, microbiota, and brown adipose tissue. (2017) (36)
Cracking the molecular origin of intrinsic tyrosine kinase activity through analysis of pathogenic gain-of-function mutations. (2013) (34)
Different tyrosine autophosphorylation requirements in fibroblast growth factor receptor-1 mediate urokinase-type plasminogen activator induction and mitogenesis. (1999) (33)
Somatic FGF9 mutations in colorectal and endometrial carcinomas associated with membranous β‐catenin (2008) (31)
Graded Levels of FGF Protein Span the Midbrain and Can Instruct Graded Induction and Repression of Neural Mapping Labels (2009) (30)
Activating Adenosine Monophosphate–Activated Protein Kinase Mediates Fibroblast Growth Factor 1 Protection From Nonalcoholic Fatty Liver Disease in Mice (2020) (28)
Induction of Urokinase-type Plasminogen Activator by Fibroblast Growth Factor (FGF)-2 Is Dependent on Expression of FGF Receptors and Does Not Require Activation of Phospholipase Cγ1* (1996) (28)
Elucidation of a four-site allosteric network in fibroblast growth factor receptor tyrosine kinases (2017) (28)
Influence of Heparin Mimetics on Assembly of the FGF·FGFR4 Signaling Complex (2010) (27)
Structural Biology of the FGF7 Subfamily (2019) (27)
The N 550 K / H Mutations in FGFR 2 Confer Differential Resistance to PD 173074 , Dovitinib , and Ponatinib ATP-Competitive Inhibitors 1 (2013) (25)
SU 6668 Is a Potent Antiangiogenic and Antitumor Agent That Induces Regression of Established Tumors 1 (2000) (23)
SH 2 domains prevent tyrosine dephosphorylation of the EGF receptor : identification of Tyr 992 as the high-affinity binding site for SH 2 domains of phospholipase CT (23)
FGF 23 promotes renal calcium reabsorption through the TRPV 5 channel (2014) (22)
A novel fibroblast growth factor-1 ligand with reduced heparin binding protects the heart against ischemia-reperfusion injury in the presence of heparin co-administration (2017) (21)
Urothelial tumor initiation requires deregulation of multiple signaling pathways: implications in target-based therapies. (2012) (21)
Molecular Insights into the Klotho-Dependent, Endocrine Mode of Action of FGF19 Subfamily Members (2007) (20)
Paracrine FGFs target skeletal muscle to exert potent anti-hyperglycemic effects (2021) (20)
Therapeutic Effects of FGF23 c‐tail Fc in a Murine Preclinical Model of X‐Linked Hypophosphatemia Via the Selective Modulation of Phosphate Reabsorption (2017) (20)
Regulation of Receptor Binding Specificity of FGF9 by an Autoinhibitory Homodimerization. (2017) (20)
Differential pre- and postsynaptic modulation of chemical transmission in the squid giant synapse by tyrosine phosphorylation. (1997) (19)
Faculty Opinions recommendation of Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development. (2018) (18)
Molecular basis for receptor tyrosine kinase A-loop tyrosine transphosphorylation (2020) (16)
Generation of recombinant cytoplasmic domain of epidermal growth factor receptor with intrinsic protein tyrosine kinase activity. (1990) (16)
Structure‐based mutational analyses in FGF7 identify new residues involved in specific interaction with FGFR2IIIb (2003) (16)
Role of SH2-containing proteins in cellular signaling by receptor tyrosine kinases. (1992) (16)
Faculty Opinions recommendation of Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. (2018) (15)
Paracrine-endocrine FGF chimeras as potent therapeutics for metabolic diseases (2019) (15)
C-FGF23 peptide alleviates hypoferremia during acute inflammation (2020) (15)
Genetic testing facilitates prepubertal diagnosis of congenital hypogonadotropic hypogonadism (2017) (13)
A G protein-coupled, IP3/protein kinase C pathway controlling the synthesis of phosphaturic hormone FGF23. (2019) (13)
CRYSTAL STRUCTURE OF A TERNARY FGF2-FGFR1-HEPARIN COMPLEX (2000) (13)
Faculty Opinions recommendation of Decoupling the Functional Pleiotropy of Stem Cell Factor by Tuning c-Kit Signaling. (2018) (11)
FGF23-induced hypophosphatemia persists in Hyp mice deficient in the WNT coreceptor Lrp6. (2013) (11)
Curtailing FGF19’s mitogenicity by suppressing its receptor dimerization ability (2020) (11)
A Conserved Allosteric Pathway in Tyrosine Kinase Regulation. (2019) (9)
Fibulin-1 Binds to Fibroblast Growth Factor 8 with High Affinity (2016) (8)
b-Klotho deficiency protects against obesity through a crosstalk between liver , microbiota , and brown adipose tissue (2018) (5)
Pregnane X receptor activation induces FGF 19-dependent tumor aggressiveness in humans and mice (2018) (5)
Fibroblast Growth Factor Binding Protein 3 (FGFBP3) impacts carbohydrate and lipid metabolism (2018) (5)
Rhenium N-heterocyclic carbene complexes block growth of aggressive cancers by inhibiting FGFR- and SRC-mediated signalling (2020) (5)
Erratum: Signal transduction by the α6β4 integrin: Distinct β4 subunit sites mediate recruitment of Shc/Grb2 and association with the cytoskeleton of hemidesmosomes (EMBO Journal (1995) 14 (4470-4481)) (2000) (5)
Synthesis of sulfosucrose derivatives for evaluation as regulators of fibroblast growth factor activity (2002) (5)
A G protein – coupled , IP 3 / protein kinase C pathway controlling the synthesis of phosphaturic hormone FGF 23 (2019) (4)
Corrigendum: Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer (2015) (4)
Frequency of Impaired Fibroblast Growth Factor Receptor 1 Signaling as a Cause of Normosmic Idiopathic Hypogonadotropic Hypogonadism. (2009) (4)
Hedgehogs like it sweet, too (2006) (3)
Faculty Opinions recommendation of Functional proteomics defines the molecular switch underlying FGF receptor trafficking and cellular outputs. (2018) (3)
In vitro reconstitution reveals cooperative mechanisms of adapter protein-mediated activation of phospholipase C-γ1 in T cells (2022) (3)
Arrythmogenic Right Ventricular Dysplasia (2016) (3)
CRYSTAL STRUCTURE OF FGF2 IN COMPLEX WITH THE EXTRACELLULAR LIGAND BINDING DOMAIN OF FGF RECEPTOR 2 (FGFR2) (2000) (2)
Molecular Insights into the Klotho-Dependent, Endocrine Mode of Action of FGF 19 Subfamily Members Running Title: Klotho-dependent, endocrine-acting FGFs (2007) (2)
FGF9 mutations in colorectal and endometrial cancers (2008) (2)
Identiﬁcation of Six Novel Autophosphorylation Sites on Fibroblast Growth Factor Receptor 1 and Elucidation of Their Importance in Receptor Activation and Signal Transduction (1996) (2)
New loci for congenital hypopituitarism: overlap with Kallmann syndrome (2009) (2)
Abstract 4733: Activating FGFR2 kinase domain mutations provide resistance to dovitinib (TKI258) (2011) (1)
CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR 9 (FGF9) (2001) (1)
1 Identification of Phosphopeptides by MALDI Q-TOF Mass Spectrometry in Positive and Negative Ion Modes after Methyl Esterification (2005) (1)
TheFunction ofGRB2inLinking theInsulin Receptor toRasSignaling Pathways (2012) (1)
Crystal Structure of Fibroblast growth factor (FGF)8b in complex with FGF Receptor (FGFR) 2c (2006) (1)
FGFR1: FGF receptor-1 (vertebrates) (fms-like kinase, flk) (1995) (1)
Albinism with Hemorrhagic Diathesis and Pigmented Reticuloendothelial Cells (2009) (1)
Faculty Opinions recommendation of Antibody mechanics on a membrane-bound HIV segment essential for GP41-targeted viral neutralization. (2011) (0)
Two FGFR kinase molecules act in concert to recruit and transphosphorylate PLC γ (2016) (0)
Crystal Structure of FGF Receptor (FGFR) 4 Tyrosine Kinase Domain (2014) (0)
Crystal Structure of FGF Receptor (FGFR) 4 Kinase Domain in Complex with FIIN-2, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming FGFR Kinase Gate-Keeper Mutations (2014) (0)
Crystal Structure Analysis of the FGF10-FGFR2b Complex (2003) (0)
NMR Experiments on Wild-Type and Mutant Fibroblast Growth Factor Receptor Kinases Reveal Conformational Dynamics Associated with Enzyme Activation (2016) (0)
1 INFLUENCE OF HEPARIN MIMETICS ON THE ASSEMBLY OF THE FGF-FGFR 4 SIGNALING COMPLEX (2010) (0)
Faculty Opinions recommendation of Interleukin-2 activity can be fine tuned with engineered receptor signaling clamps. (2018) (0)
Binding-Interface Dynamics between Calmodulin and its Targets Revealed using Nonperturbative Infrared Probe Groups (2017) (0)
High frequency of FGFR1 mutations in patients with congenital hypogonadotropic hypogonadism and split hand/foot malformation (2014) (0)
Crystal structure of human FGF23 (2007) (0)
CRYSTAL STRUCTURE OF THE TYROSINE KINASE DOMAIN OF FIBROBLAST GROWTH FACTOR RECEPTOR 1 IN COMPLEX WITH SU5402 INHIBITOR (1998) (0)
organizer activity of FGF8 in the brain Structural basis by which alternative splicing modulates the (2006) (0)
Crystal Structure of the Tyrosine Kinase Domain of FGF Receptor 4 in Complex with Ponatinib (2014) (0)
Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domains Trapped in Trans-Phosphorylation Reaction (2009) (0)
Crystal structure of FGF20 dimer (2009) (0)
Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic E565A Mutation Responsible for Pfeiffer Syndrome (2007) (0)
MAMMALIAN FGF FAMILY Growth Factor Family : THE COMPLETE Receptor Specificity of the Fibroblast Mechanisms of Signal Transduction : (2006) (0)
Structural studies of receptor tyrosine kinases (1996) (0)
Gatekeeper mutations activate FGF receptor tyrosine kinases by destabilizing the autoinhibited state. (2023) (0)
Crystal structure of human FHF1b (FGF12b) (2003) (0)
KLB, Encoding the Co-receptor for FGF21, is Mutated in Congenital Hypogonadotropic Hypogonadism (2015) (0)
FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis (2020) (0)
Functional characterization of FGFR2 mutations in melanoma reveals multiple mechanisms of inactivation (2006) (0)
Structural Biology of FGF signaling in Human Development and Disease (2007) (0)
FGFR2: FGF receptor-2 (vertebrates) (Bacterial expressed) kinase, bek, Keratinocyte growth factor receptor) (1995) (0)
Crystal Structure of FGF Receptor 3 (FGFR3) Kinase Domain Harboring the K650E Mutation, a Gain-of-Function Mutation Responsible for Thanatophoric Dysplasia Type II and Spermatocytic Seminoma (2013) (0)
Renal Physiol Michel Baum Jyothsna Gattineni , Katherine Twombley , Regina Goetz , Moosa Mohammadi and receptors 3 and 4 fibroblast growth factor 23 is mediated by FGF levels by 3 Vitamin D 2 Regulation of serum (2011) (0)
Crystal Structure of an Asymmetric Dimer of FGF Receptor 3 Kinases Trapped in A-loop Tyrosine Transphosphorylation Reaction (2020) (0)
Rhenium N-heterocyclic carbene complexes block growth of aggressive cancers by inhibiting FGFR- and SRC-mediated signalling (2020) (0)
DDH235 2313..2324 (2004) (0)
Crystal Structure of FGF Receptor (FGFR) 4 Kinase Harboring the V550L Gate-Keeper Mutation in Complex with FIIN-3, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming FGFR kinase Gate-Keeper Mutations (2014) (0)
LOSS-OF-FUNCTION FGFR2 MUTATIONS IN MELANOMA (2017) (0)
Abstract A61: Profile of Ponatinib, BGJ398, AZ4547 and DCC-2036 against FGFR2 Mutations identified in a Dovitinib Resistance BaF3 Screen (2012) (0)
The FGF signaling pathway and human disease (2006) (0)
Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K659N Mutation Responsible for an Unclassified Craniosynostosis Syndrome in Space Group C2. (2013) (0)
Faculty Opinions recommendation of Structural basis of semaphorin-plexin recognition and viral mimicry from Sema7A and A39R complexes with PlexinC1. (2011) (0)
Crystal Structure of FGF1 complexed with the ectodomain of FGFR1c exhibiting an ordered ligand specificity-determining betaC'-betaE loop (2011) (0)
CRYSTAL STRUCTURE OF A DIMERIC FGF2-FGFR1 COMPLEX (2000) (0)
Crystal Structure of the 3 Ig form of FGFR3c in complex with FGF1 (2004) (0)
Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic Gain-of-Function K659E Mutation Identified in Endometrial Cancer. (2013) (0)
Crystal structure of FGF1 complexed with the ectodomain of FGFR2b harboring the A172F Pfeiffer syndrome mutation (2011) (0)
LOSS-OF-FUNCTION FGFR 2 MUTATIONS IN MELANOMA (2012) (0)
Familial tumoral calcinosis is characterized by ectopic calcifications and hyperphosphatemia due to inactivating mutations in FGF 23 or UDP-N-acetyl-α-D-galactosamine : polypeptide (2007) (0)
CRYSTAL STRUCTURE OF THE TYROSINE KINASE DOMAIN OF FIBROBLAST GROWTH FACTOR RECEPTOR 1 (1997) (0)
Faculty Opinions recommendation of Differential requirement of Grb2 and PI3-kinase in HGF/SF-induced cell motility and tubulogenesis. (2018) (0)
Author response: Elucidation of a four-site allosteric network in fibroblast growth factor receptor tyrosine kinases (2016) (0)
- FGFR3: FGF receptor-3 (vertebrates) (1995) (0)
Structural basis of FGF23 hormone signaling (2021) (0)
Crystal Structure of FGF Receptor (FGFR) 4 Kinase Domain Harboring the V550L Gate-Keeper Mutation (2014) (0)
Faculty Opinions recommendation of Tuning cytokine receptor signaling by re-orienting dimer geometry with surrogate ligands. (2018) (0)
Crystal Structure of the Tyrosine Kinase Domain of FGF Receptor 2 harboring an E565A/K659M Double Gain-of-Function Mutation (2017) (0)
Crystal Structure of FGF1 complexed with the ectodomain of FGFR2b harboring P253R Apert mutation (2011) (0)
Crystal Structure of Fibroblast Growth Factor 4 (FGF4) (2001) (0)
CRYSTAL STRUCTURE OF THE TYROSINE KINASE DOMAIN OF FIBROBLAST GROWTH FACTOR RECEPTOR 1 IN COMPLEX WITH SU4984 INHIBITOR (1998) (0)
Symposium S16: FGFs: Old Molecules, New Tricks (2004) (0)
Elucidating the Activating Mechanism of Gatekeeper Mutations on Receptor Tyrosine Kinases (2020) (0)
CRYSTAL STRUCTURE OF PRO253ARG APERT MUTANT FGF RECEPTOR 2 (FGFR2) IN COMPLEX WITH FGF2 (2001) (0)
Molecular Insights into the Klotho-Dependent, Endocrine Mode of Action of Fibroblast Growth Factor 19 Subfamily Members (cid:1) (2007) (0)
CRYSTAL STRUCTURE OF FGF1 IN COMPLEX WITH THE EXTRACELLULAR LIGAND BINDING DOMAIN OF FGF RECEPTOR 1 (FGFR1) (2000) (0)
FGFR4: FGF receptor-4 (vertebrates) (1995) (0)
Crystal Structure of a 1:1:1 FGF23-FGFR1c-aKlotho Ternary Complex (2018) (0)
Faculty Opinions recommendation of Structure of the IFNγ receptor complex guides design of biased agonists. (2019) (0)
Crystal Structure of Tyrosine Phosphorylated Activated FGF Receptor 2 (FGFR2) Kinase Domain in Complex with ATP Analog and Substrate Peptide (2007) (0)
Crystal structure of human FGF19 (2007) (0)
Crystal Structure of FGF Receptor 2 Tyrosine Kinase Domain Harboring the D650V Activating Mutation (2017) (0)
Adenomatous Polyposis, Familial (2009) (0)
Abstract 19345: A Novel Fibroblast Growth Factor-1 Ligand With Reduced Heparin Binding Protects the Heart Against Ischemia-Reperfusion Injury in the Presence of Heparin Co-Treatment (2016) (0)
Faculty Opinions recommendation of Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes. (2020) (0)
Induces Regression of Established Tumors SU 6668 Is a Potent Antiangiogenic and Antitumor Agent That Updated (2000) (0)
Allostery and Conformational Dynamics in Tyrosine Kinase Regulation (2020) (0)
Characterization of Disease Causing Mutations Associated with FGF Receptor Tyrosine Kinases using NMR Spectroscopy (2017) (0)
Faculty Opinions recommendation of Structural and energetic mechanisms of cooperative autoinhibition and activation of Vav1. (2010) (0)
Crystal structure of a monomeric human FGF9 in complex with the ectodomain of human FGFR1c (2017) (0)
A Tyrosine-Phosphorylated Peptide ofthe Fibroblast GrowthFactor Receptor (Flg) Isa Binding Site forthe SH2DomainofPhospholipase C--yl (1991) (0)
Crystal Structure of FGF Receptor (FGFR) 4 Kinase Harboring the V550L Gate-Keeper Mutation in Complex With FIIN-2, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming FGFR Kinase Gate-Keeper Mutations (2014) (0)
Abstract 1477: In vitro reconstitution reveals cooperative mechanisms of adapter protein-mediated activation of phospholipase C-gamma1 in T cells (2023) (0)
Subfamily Ligands Paracrine Fibroblast Growth Factor 8 Klotho Coreceptors Inhibit Signaling by (2012) (0)
Fibroblast Growth Factor Binding Protein 3 (FGFBP3) impacts carbohydrate and lipid metabolism (2018) (0)
Crystal Structure of Unphosphorylated Unactivated Wild Type FGF Receptor 2 (FGFR2) Kinase Domain (2007) (0)
Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K659N Mutation Responsible for an Unclassified Craniosynostosis Syndrome. (2007) (0)
Faculty Opinions recommendation of Fibroblast growth factor-21 regulates PPARγ activity and the antidiabetic actions of thiazolidinediones. (2012) (0)
Faculty Opinions recommendation of Inductive signal and tissue responsiveness defining the tectum and the cerebellum. (2018) (0)
Crystal Structure of Human Fibroblast Growth Factor Homologous Factor 2A (FHF2A), also referred to as Fibroblast Growth Factor 13A (FGF13A) (2009) (0)
Faculty Opinions recommendation of Oncogenic mutations counteract intrinsic disorder in the EGFR kinase and promote receptor dimerization. (2013) (0)
Crystal Structure of the Activated FGF Receptor 2 (FGFR2) Kinase Domain in complex with the cSH2 domain of Phospholipase C gamma (PLCgamma) (2016) (0)
Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Gain-of-Function K659Q Mutation. (2013) (0)
FGF-FGFR Signaling in Cancer (2014) (0)
Andersen disease (2019) (0)
Aortic Root to Right Heart Shunts (2009) (0)

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