Morris J. Birnbaum
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Morris J. Birnbaum's Degrees
- Masters Electrical Engineering Stanford University
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(Suggest an Edit or Addition)Morris J. Birnbaum's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Regulation of Neuronal Survival by the Serine-Threonine Protein Kinase Akt (1997) (2549)
- Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ) (2001) (1645)
- AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus (2004) (1605)
- AMP-activated protein kinase induces a p53-dependent metabolic checkpoint. (2005) (1544)
- Expression of a Constitutively Active Akt Ser/Thr Kinase in 3T3-L1 Adipocytes Stimulates Glucose Uptake and Glucose Transporter 4 Translocation* (1996) (1316)
- Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance. (2007) (1110)
- AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation (2002) (1024)
- Akt1/PKBα Is Required for Normal Growth but Dispensable for Maintenance of Glucose Homeostasis in Mice* (2001) (1018)
- A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle. (2001) (970)
- Essential Regulation of Cell Bioenergetics by Constitutive InsP3 Receptor Ca2+ Transfer to Mitochondria (2010) (902)
- Convergent evidence for impaired AKT1-GSK3β signaling in schizophrenia (2004) (895)
- Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta). (2001) (872)
- Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin (2011) (738)
- AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury. (2004) (732)
- Biguanides suppress hepatic glucagon signaling by decreasing production of cyclic AMP (2012) (725)
- Role of Akt/protein kinase B in metabolism (2002) (660)
- The role of FoxO in the regulation of metabolism (2008) (579)
- MICU1 Is an Essential Gatekeeper for MCU-Mediated Mitochondrial Ca2+ Uptake that Regulates Cell Survival (2012) (550)
- Memory CD8(+) T cells use cell-intrinsic lipolysis to support the metabolic programming necessary for development. (2014) (542)
- Identification of a novel gene encoding an insulin-responsive glucose transporter protein (1989) (532)
- Hepatic Acetyl CoA Links Adipose Tissue Inflammation to Hepatic Insulin Resistance and Type 2 Diabetes (2015) (521)
- The AMP-activated protein kinase alpha2 catalytic subunit controls whole-body insulin sensitivity. (2003) (503)
- Role for Akt3/Protein Kinase Bγ in Attainment of Normal Brain Size (2005) (493)
- Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1α transcription coactivator (2007) (475)
- Cloning and characterization of a cDNA encoding the rat brain glucose-transporter protein. (1986) (456)
- Regulation of Insulin-Stimulated Glucose Transporter GLUT4 Translocation and Akt Kinase Activity by Ceramide (1998) (443)
- Nomenclature of the GLUT/SLC2A family of sugar/polyol transport facilitators. (2002) (389)
- Cyclic AMP Promotes Neuronal Survival by Phosphorylation of Glycogen Synthase Kinase 3β (2000) (380)
- Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB (1999) (376)
- Identification of a Proline-rich Akt Substrate as a 14-3-3 Binding Partner* (2003) (372)
- Exercise induces isoform-specific increase in 5'AMP-activated protein kinase activity in human skeletal muscle. (2000) (362)
- Inhibition of Akt Kinase by Cell-permeable Ceramide and Its Implications for Ceramide-induced Apoptosis* (1998) (356)
- GLUT-1 deficiency syndrome caused by haploinsufficiency of the blood-brain barrier hexose carrier (1998) (354)
- Role for Akt3/protein kinase Bgamma in attainment of normal brain size. (2005) (351)
- The Small Intestine Converts Dietary Fructose into Glucose and Organic Acids. (2018) (342)
- Construction and Characterization of a Conditionally Active Version of the Serine/Threonine Kinase Akt* (1998) (341)
- Early diabetes and abnormal postnatal pancreatic islet development in mice lacking Glut-2 (1997) (338)
- The Effects of Wortmannin on Rat Skeletal Muscle (1995) (335)
- Regulation of pancreatic β-cell growth and survival by the serine/threonine protein kinase Akt1/PKBα (2001) (330)
- Isoform-specific Regulation of Insulin-dependent Glucose Uptake by Akt/Protein Kinase B* (2003) (328)
- A Role for Protein Kinase Bβ/Akt2 in Insulin-Stimulated GLUT4 Translocation in Adipocytes (1999) (328)
- Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1 (2012) (322)
- Akt1/protein kinase Bα is critical for ischemic and VEGF-mediated angiogenesis (2005) (320)
- Pretranslational suppression of a glucose transporter protein causes insulin resistance in adipocytes from patients with non-insulin-dependent diabetes mellitus and obesity. (1991) (309)
- The regulation of AMP-activated protein kinase by H(2)O(2). (2001) (294)
- Role of AMP-activated Protein Kinase in Cyclic AMP-dependent Lipolysis In 3T3-L1 Adipocytes* (2003) (293)
- Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration (2012) (291)
- Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha. (2001) (289)
- Protein Kinase C θ Inhibits Insulin Signaling by Phosphorylating IRS1 at Ser1101* (2004) (274)
- Transformation of rat fibroblasts by FSV rapidly increases glucose transporter gene transcription. (1987) (270)
- Activation of SOCS-3 by Resistin (2005) (270)
- AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species. (2010) (269)
- Akt2 is required for hepatic lipid accumulation in models of insulin resistance. (2009) (261)
- Physiological role of AMP-activated protein kinase (AMPK): insights from knockout mouse models. (2001) (256)
- Loss of Akt1 leads to severe atherosclerosis and occlusive coronary artery disease. (2007) (252)
- The immune response attenuates growth and nutrient storage in Drosophila by reducing insulin signaling (2009) (247)
- Insulin Increases the Association of Akt-2 with Glut4-containing Vesicles* (1998) (244)
- Akt1/protein kinase Balpha is critical for ischemic and VEGF-mediated angiogenesis. (2005) (240)
- Transduction of Growth or Mitogenic Signals into Translational Activation of TOP mRNAs Is Fully Reliant on the Phosphatidylinositol 3-Kinase-Mediated Pathway but Requires neither S6K1 nor rpS6 Phosphorylation (2002) (239)
- Growth factors rapidly induce expression of the glucose transporter gene. (1988) (238)
- Pretranslational suppression of an insulin-responsive glucose transporter in rats with diabetes mellitus. (1989) (234)
- Defects in secretion, aggregation, and thrombus formation in platelets from mice lacking Akt2. (2004) (229)
- Pim and Akt oncogenes are independent regulators of hematopoietic cell growth and survival. (2005) (229)
- Akt/Protein Kinase B Isoforms Are Differentially Regulated by Epidermal Growth Factor Stimulation* (2000) (225)
- Unraveling the Regulation of Hepatic Metabolism by Insulin (2017) (225)
- The translational inhibitor 4E-BP is an effector of PI(3)K/Akt signalling and cell growth in Drosophila (2001) (220)
- Akt1 Regulates a JNK Scaffold during Excitotoxic Apoptosis (2002) (210)
- Leptin activates hypothalamic acetyl-CoA carboxylase to inhibit food intake (2007) (209)
- The Role of Glycogen Synthase Kinase 3β in Insulin-stimulated Glucose Metabolism* (1999) (208)
- Insulin Regulates Adipocyte Lipolysis via an Akt-Independent Signaling Pathway (2010) (204)
- Selective inhibition of Ras, phosphoinositide 3 kinase, and Akt isoforms increases the radiosensitivity of human carcinoma cell lines. (2005) (195)
- Akt and CHIP coregulate tau degradation through coordinated interactions (2008) (195)
- Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production. (2016) (194)
- Protein Kinase A-Dependent and -Independent Signaling Pathways Contribute to Cyclic AMP-Stimulated Proliferation (1999) (188)
- Contribution of Insulin and Akt1 Signaling to Endothelial Nitric Oxide Synthase in the Regulation of Endothelial Function and Blood Pressure (2009) (181)
- Construction of human activity-based phosphorylation networks (2013) (166)
- The Role of AMPK and mTOR in Nutrient Sensing in Pancreatic β-Cells* (2007) (160)
- Insulin, but Not Contraction, Activates Akt/PKB in Isolated Rat Skeletal Muscle* (1998) (159)
- An energetic tale of AMPK-independent effects of metformin. (2010) (155)
- Adiponectin suppresses gluconeogenic gene expression in mouse hepatocytes independent of LKB1-AMPK signaling. (2011) (155)
- Regulation of Fat Cell Mass by Insulin in Drosophila melanogaster (2009) (153)
- Protein kinase C Theta inhibits insulin signaling by phosphorylating IRS1 at Ser(1101). (2004) (153)
- The PP2A-Associated Protein α4 Is an Essential Inhibitor of Apoptosis (2004) (149)
- Opposing Roles for Akt1 and Akt2 in Rac/Pak Signaling and Cell Migration* (2006) (147)
- Molecular and Genetic Studies Imply Akt-mediated Signaling Promotes Protein Kinase CβII Alternative Splicing via Phosphorylation of Serine/Arginine-rich Splicing Factor SRp40* (2005) (144)
- Memory CD8+ T Cells Use Cell-Intrinsic Lipolysis to Support the Metabolic Programming Necessary for Development. (2018) (142)
- Insulin signaling to hepatic lipid metabolism in health and disease (2011) (140)
- A conserved role for phosphatidylinositol 3-kinase but not Akt signaling in mitochondrial adaptations that accompany physiological cardiac hypertrophy. (2007) (136)
- Glucose deprivation and hexose transporter polypeptides of murine fibroblasts. (1986) (136)
- The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver (2014) (135)
- The acquisition of increased insulin-responsive hexose transport in 3T3-L1 adipocytes correlates with expression of a novel transporter gene. (1989) (129)
- PPARγ contributes to PKM2 and HK2 expression in fatty liver (2012) (128)
- Hepatic Insulin Signaling is Dispensable for Suppression of Glucose Output by Insulin in Vivo (2015) (126)
- Neuregulin Signaling through a PI3K/Akt/Bad Pathway in Schwann Cell Survival (2001) (125)
- Regulation of Angiogenesis by Glycogen Synthase Kinase-3β* (2002) (123)
- Akt1 and Akt2 are required for αβ thymocyte survival and differentiation (2007) (118)
- Membrane depolarization is the trigger for PI3K/Akt activation and leads to the generation of ROS. (2012) (118)
- Distinct signals in the GLUT4 glucose transporter for internalization and for targeting to an insulin-responsive compartment (1995) (118)
- Kinetics of GLUT1 and GLUT4 glucose transporters expressed in Xenopus oocytes. (1993) (117)
- The role of AMPK and mTOR in nutrient sensing in pancreatic beta-cells. (2007) (115)
- Postprandial hepatic lipid metabolism requires signaling through Akt2 independent of the transcription factors FoxA2, FoxO1, and SREBP1c. (2011) (114)
- The insulin-sensitive glucose transporter. (1992) (112)
- Isolation of a Drosophila genomic sequence homologous to the kinase domain of the human insulin receptor and detection of the phosphorylated Drosophila receptor with an anti-peptide antibody. (1986) (111)
- Identification of Wortmannin-sensitive Targets in 3T3-L1 Adipocytes (1999) (111)
- The aetiology and molecular landscape of insulin resistance (2021) (110)
- ADP-ribosylation factor 6 regulates insulin secretion through plasma membrane phosphatidylinositol 4,5-bisphosphate (2003) (109)
- Oxalic acid and diacylglycerol 36:3 are cross-species markers of sleep debt (2015) (108)
- A Leu-Leu sequence is essential for COOH-terminal targeting signal of GLUT4 glucose transporter in fibroblasts. (1994) (108)
- Turning down insulin signaling. (2001) (105)
- Selective suppression of AMP-activated protein kinase in skeletal muscle: update on 'lazy mice'. (2001) (105)
- TLR4-Mediated AKT Activation Is MyD88/TRIF Dependent and Critical for Induction of Oxidative Phosphorylation and Mitochondrial Transcription Factor A in Murine Macrophages (2012) (105)
- Signaling Pathways Mediating Insulin‐Stimulated Glucose Transport (1999) (100)
- The Pleiotropic Actions of Adiponectin are Initiated via Receptor-Mediated Activation of Ceramidase Activity (2010) (97)
- Akt1 and Akt2 are required for alphabeta thymocyte survival and differentiation. (2007) (97)
- Insulin-responsive Aminopeptidase Trafficking in 3T3-L1 Adipocytes* (2000) (96)
- The role of FOXO in the regulation of metabolism (2009) (93)
- Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models (2018) (93)
- The PP2A-associated protein alpha4 is an essential inhibitor of apoptosis. (2004) (93)
- Expansion of hepatic tumor progenitor cells in Pten-null mice requires liver injury and is reversed by loss of AKT2. (2010) (91)
- The critical role of AKT2 in hepatic steatosis induced by PTEN loss. (2010) (91)
- Isoform-specific subcellular targeting of glucose transporters in mouse fibroblasts (1992) (91)
- Spontaneous Hepatocellular Carcinoma after the Combined Deletion of Akt Isoforms. (2016) (89)
- Early diabetes and abnormal postnatal pancreatic islet development in mice lacking Glut-2 (1998) (87)
- Activating AMP-activated protein kinase without AMP. (2005) (87)
- Isoform-specific requirement for Akt1 in the developmental regulation of cellular metabolism during lactation. (2006) (86)
- Akt1 and Akt2 promote peripheral B-cell maturation and survival. (2010) (85)
- Insulin receptor substrate 1 mediates insulin and insulin-like growth factor I-stimulated maturation of Xenopus oocytes. (1993) (84)
- PGC‐1α gene expression is down‐regulated by Akt‐mediated phosphorylation and nuclear exclusion of FoxO1 in insulin‐stimulated skeletal muscle (2005) (84)
- The tyrosine kinases Syk and Lyn exert opposing effects on the activation of protein kinase Akt/PKB in B lymphocytes. (1999) (79)
- Dissociation of pp70 ribosomal protein S6 kinase from insulin-stimulated glucose transport in 3T3-L1 adipocytes. (1993) (79)
- Akt1 deficiency in schizophrenia and impairment of hippocampal plasticity and function (2012) (79)
- Loss of PIP5KIgamma, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes. (2008) (78)
- Identification of the carboxy terminus as important for the isoform- specific subcellular targeting of glucose transporter proteins (1993) (78)
- Isoform-specific regulation of adipocyte differentiation by Akt/protein kinase Balpha. (2008) (77)
- Natural and inducible TH17 cells are regulated differently by Akt and mTOR pathways (2013) (76)
- AKT-dependent HspB1 (Hsp27) Activity in Epidermal Differentiation* (2007) (76)
- Identification of a nonneuronal isoform of synaptotagmin. (1995) (74)
- A noncanonical, GSK3-independent pathway controls postprandial hepatic glycogen deposition. (2013) (69)
- A role for the serine/threonine kinase, Akt, in insulin-stimulated glucose uptake. (1997) (69)
- Akt2, phosphatidylinositol 3-kinase, and PTEN are in lipid rafts of intestinal cells: role in absorption and differentiation. (2004) (68)
- Kinetic analysis of glucose transporter trafficking in fibroblasts and adipocytes. (1995) (67)
- Akt Deficiency Attenuates Muscle Size and Function but Not the Response to ActRIIB Inhibition (2010) (67)
- Insulin-stimulated oocyte maturation requires insulin receptor substrate 1 and interaction with the SH2 domains of phosphatidylinositol 3-kinase (1993) (66)
- The Role of PDE3B Phosphorylation in the Inhibition of Lipolysis by Insulin (2015) (66)
- Biosynthetic precursors and in vitro translation products of the glucose transporter of human hepatocarcinoma cells, human fibroblasts, and murine preadipocytes. (1985) (66)
- Polyoma middle T antigen activates the Ser/Thr kinase Akt in a PI3-kinase-dependent manner. (1998) (66)
- GLUT4, AMP kinase, but not the insulin receptor, are required for hepatoportal glucose sensor-stimulated muscle glucose utilization. (2003) (65)
- Differentiation-dependent Suppression of Platelet-derived Growth Factor Signaling in Cultured Adipocytes* (1999) (64)
- AMP kinase is not required for the GLUT4 response to exercise and denervation in skeletal muscle. (2004) (64)
- Role of p21ras in insulin-stimulated glucose transport in 3T3-L1 adipocytes. (1994) (64)
- Constitutively active Akt1 expression in mouse pancreas requires S6 kinase 1 for insulinoma formation. (2008) (64)
- Activation of Akt Is Essential for the Propagation of Mitochondrial Respiratory Stress Signaling and Activation of the Transcriptional Coactivator Heterogeneous Ribonucleoprotein A2 (2010) (63)
- The regulation by insulin of glucose transporter gene expression in 3T3 adipocytes. (1989) (63)
- Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy (2017) (62)
- Control of gluconeogenesis by metformin: does redox trump energy charge? (2014) (62)
- The rat facilitated glucose transporter gene. Transformation and serum-stimulated transcription initiate from identical sites. (1988) (61)
- A novel Akt3 mutation associated with enhanced kinase activity and seizure susceptibility in mice. (2011) (61)
- Metabolic drivers of non-alcoholic fatty liver disease (2020) (59)
- Different Signaling Roles of SHPTP2 in Insulin-induced GLUT1 Expression and GLUT4 Translocation (*) (1995) (59)
- Expression of a glucose transporter gene cloned from brain in cellular models of insulin resistance: dexamethasone decreases transporter mRNA in primary cultured adipocytes. (1989) (56)
- Normal Akt/PKB with reduced PI3K activation in insulin-resistant mice. (2001) (56)
- Loss of Akt1 in Mice Increases Energy Expenditure and Protects against Diet-Induced Obesity (2011) (55)
- Targeting of the "insulin-responsive" glucose transporter (GLUT4) to the regulated secretory pathway in PC12 cells [published erratum appears in J Cell Biol 1993 Sep;122(5):following 1143] (1993) (55)
- Lack of AKT in adipocytes causes severe lipodystrophy (2016) (52)
- Platelet-derived growth factor (PDGF) stimulates glucose transport in 3T3-L1 adipocytes overexpressing PDGF receptor by a pathway independent of insulin receptor substrates. (2003) (52)
- Akt‐mediated foxo1 inhibition is required for liver regeneration (2016) (51)
- SREBP1c-CRY1 signalling represses hepatic glucose production by promoting FOXO1 degradation during refeeding (2016) (51)
- A cDNA encoding protein kinase C identifies two species of mRNA in brain and GH3 cells. (1986) (51)
- Lysophosphatidic acid induces cell migration through the selective activation of Akt1 (2008) (49)
- 1 Cellular insulin action and insulin resistance (1993) (49)
- AMPK supports growth in Drosophila by regulating muscle activity and nutrient uptake in the gut. (2010) (49)
- mTORC1 stimulates phosphatidylcholine synthesis to promote triglyceride secretion (2017) (48)
- Rapamycin Induces Mitogen-activated Protein (MAP) Kinase Phosphatase-1 (MKP-1) Expression through Activation of Protein Kinase B and Mitogen-activated Protein Kinase Kinase Pathways* (2013) (47)
- Akt is required for Stat5 activation and mammary differentiation (2010) (47)
- Ciliary Neurotrophic Factor Stimulates Muscle Glucose Uptake by a PI3-Kinase–Dependent Pathway That Is Impaired With Obesity (2009) (47)
- Molecular aspects of fructose metabolism and metabolic disease. (2021) (45)
- GDF-15 Neutralization Alleviates Platinum-Based Chemotherapy-Induced Emesis, Anorexia, and Weight Loss in Mice and Nonhuman Primates. (2020) (45)
- Targeting hepatic glutaminase activity to ameliorate hyperglycemia (2018) (44)
- ADP-Ribosylation Factor 6 Delineates Separate Pathways Used by Endothelin 1 and Insulin for Stimulating Glucose Uptake in 3T3-L1 Adipocytes (2001) (43)
- Akt pathway is hypoactivated by synergistic actions of diabetes mellitus and hypercholesterolemia resulting in advanced coronary artery disease. (2010) (42)
- Diabetes: Dialogue between muscle and fat (2001) (42)
- A role for Raf-1 in the divergent signaling pathways mediating insulin-stimulated glucose transport. (1994) (42)
- Interactive roles of Ras, insulin receptor substrate-1, and proteins with Src homology-2 domains in insulin signaling in Xenopus oocytes. (1994) (39)
- Glucagon: acute actions on hepatic metabolism (2016) (39)
- Quantitative Analysis of Anti-apoptotic Function of Akt in Akt1 and Akt2 Double Knock-out Mouse Embryonic Fibroblast Cells under Normal and Stressed Conditions* (2006) (38)
- Phosphorylation of GATA-6 is required for vascular smooth muscle cell differentiation after mTORC1 inhibition (2015) (38)
- PI3K regulates pleckstrin-2 in T-cell cytoskeletal reorganization. (2005) (37)
- Mio/dChREBP coordinately increases fat mass by regulating lipid synthesis and feeding behavior in Drosophila. (2012) (37)
- Role of insulin-like growth factor-binding protein 5 (IGFBP5) in organismal and pancreatic beta-cell growth. (2010) (34)
- Innate Immune Signaling in Drosophila Blocks Insulin Signaling by Uncoupling PI(3,4,5)P3 Production and Akt Activation (2018) (34)
- Lipolysis: more than just a lipase. (2003) (34)
- Differential regulation of Akt/protein kinase B isoforms during cell cycle progression (2009) (33)
- Cellular insulin action and insulin resistance. (1993) (33)
- Transformation stimulates glucose transporter gene expression in the absence of protein kinase C. (1989) (33)
- On the InterAktion between hexokinase and the mitochondrion. (2004) (32)
- De-Meaning of Metabolism (2012) (31)
- Linker region of Akt1/protein kinase Balpha mediates platelet-derived growth factor-induced translocation and cell migration. (2008) (31)
- AKT 1 and AKT 2 maintain hematopoietic stem cell function by regulating reactive oxygen species (2010) (30)
- Genomics: Drugs, diabetes and cancer (2011) (27)
- Distinct mTORC1 pathways for transcription and cleavage of SREBP-1c (2012) (26)
- Protein Kinase B/Akt Is a Novel Cysteine String Protein Kinase That Regulates Exocytosis Release Kinetics and Quantal Size* (2006) (26)
- Three-amino-acid-loop-extension homeodomain factor Meis3 regulates cell survival via PDK1 (2010) (26)
- Pharmacologic inhibition of ketohexokinase prevents fructose-induced metabolic dysfunction (2021) (26)
- Proteolytic Cleavage of AMPKα and Intracellular MMP9 Expression Are Both Required for TLR4-Mediated mTORC1 Activation and HIF-1α Expression in Leukocytes (2015) (25)
- Hepatic Gi signaling regulates whole-body glucose homeostasis (2018) (25)
- Characterization of the mitogen-activated protein kinase/90-kilodalton ribosomal protein S6 kinase signaling pathway in 3T3-L1 adipocytes and its role in insulin-stimulated glucose transport. (1994) (25)
- Insulin Is Required to Maintain Albumin Expression by Inhibiting Forkhead Box O1 Protein* (2015) (24)
- The role of mouse Akt2 in insulin-dependent suppression of adipocyte lipolysis in vivo (2015) (24)
- Insulin-Dependent Regulation of mTORC2-Akt-FoxO Suppresses TLR4 Signaling in Human Leukocytes: Relevance to Type 2 Diabetes (2016) (24)
- The Combined Deletion of S6K1 and Akt2 Deteriorates Glycemic Control in a High-Fat Diet (2012) (23)
- ADaPting to Energetic Stress (2011) (22)
- mTORC1 Down-Regulates Cyclin-Dependent Kinase 8 (CDK8) and Cyclin C (CycC) (2015) (22)
- Glucocorticoids regulate the expression of a rat growth hormone gene lacking 5' flanking sequences. (1986) (22)
- Akt2 and SGK3 are both determinants of postnatal hair follicle development (2009) (21)
- The regulation of glucose transporter gene expression by cyclic adenosine monophosphate in NIH3T3 fibroblasts. (1989) (21)
- JUND regulates pancreatic β cell survival during metabolic stress (2019) (20)
- Akt recruits Dab2 to albumin endocytosis in the proximal tubule. (2014) (20)
- Phosphatidylinositol 3-kinase binding to polyoma virus middle tumor antigen mediates elevation of glucose transport by increasing translocation of the GLUT1 transporter. (1995) (18)
- Inhibition of ketohexokinase in adults with NAFLD reduces liver fat and inflammatory markers: A randomized phase 2 trial. (2021) (17)
- Role of PI3K/Akt signaling in TRAIL- and radiation-induced gastrointestinal apoptosis (2008) (16)
- Regulation of Gastric Acid Secretion by PKB/Akt2 (2006) (14)
- Novel role for SGK3 in glucose homeostasis revealed in SGK3/Akt2 double-null mice. (2011) (13)
- Regulation of renal tubular glucose reabsorption by Akt2/PKBβ. (2010) (13)
- Skeletal Muscle Metabolism (2012) (13)
- Erratum: Memory CD8 + T Cells Use Cell-Intrinsic Lipolysis to Support the Metabolic Programming Necessary for Development (Immunity (2014) 41(1) (75–88), (S1074761314002246) (10.1016/j.immuni.2014.06.005)) (2018) (12)
- Role of PI3K/Akt signaling in TRAIL- and radiation-induced gastrointestinal apoptosis. (2006) (12)
- Lipolysis (2003) (12)
- The Polycomb protein, Bmi1, regulates insulin sensitivity (2014) (11)
- Pharma and Academia: What We Have Here Is a Failure to Communicate. (2016) (10)
- When the usual insulin is just not enough (2007) (8)
- The insulin-regulatable glucose transporter GLUT-4 (1995) (7)
- Rejoinder: Genetic Research into the Causes of Type 2 Diabetes Mellitus (2005) (7)
- Signalling pathways mediating insulin-activated glucose transport (1996) (5)
- Assaying tyrosine phosphorylation of insulin receptor and insulin receptor substrates. (2003) (5)
- RhoGAP: the next big thing for small mice? (2002) (4)
- Sweet Conundrum (2008) (4)
- Of mice and men: not ExAKTly the same? (2011) (4)
- Akt and mTOR pathways differentially regulate the development of natural and inducible TH17 cells (2013) (3)
- Role of Insulin-Like Growth Factor-Binding Protein 5 (IGFBP5) in Organismal and Pancreatic β-Cell Growth. (2009) (3)
- University of Dundee The LKB 1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver (2014) (3)
- Publisher Correction: Targeting hepatic glutaminase activity to ameliorate hyperglycemia (2018) (2)
- 2O Growth differentiation factor 15 (GDF-15) neutralization reverses cancer cachexia, restores physical performance and mitigates emesis associated with platinum-based chemotherapy (2020) (2)
- Erratum: Early diabetes and abnormal postnatal pancreatic islet development in mice lacking Glut-2 (1997) (2)
- Phosphatidylinositol 3-kinase binding to polyoma virus middle tumor antigen mediates elevation of glucose transport by increasing translocation of the GLUT 1 transporter (2005) (2)
- advanced coronary artery disease. (2010) (1)
- Regulation of Glucose and Lipid Metabolism by Akt/PKB (2007) (1)
- Chapter 3 – Principles of Hormone Action (2016) (1)
- ROLE OF SERINE/THREONINE PROTEIN KINASE, Raf-1, IN INSULIN MEDIATED METABOLIC SIGNALING (2002) (1)
- CNTF Stimulates Muscle Glucose Uptake by a PI3-Kinase Dependent Pathway that is Impaired with Obesity (2009) (1)
- Retraction: Natural and inducible TH17 cells are regulated differently by Akt and mTOR pathways (2014) (1)
- Social Bonds of Female Baboons Enhance Infant Survival (2003) (1)
- SHIPing news: a new way to keep your weight down. (2005) (1)
- 19 Regulation of Cell Growth in the Endocrine Pancreas (2004) (0)
- Retractions and Errata (2009) (0)
- Henryk Dudek , Serine-Threonine Protein Kinase Akt Regulation of Neuronal Survival (2009) (0)
- Identification ofa nonneuronalisoformofsynaptotagmin (1995) (0)
- Protein Kinase C (cid:1) Inhibits Insulin Signaling by Phosphorylating IRS1 at (2004) (0)
- Supplementary Information Construction of Human Activity-Based Phosphorylation Networks (2013) (0)
- The regulation of hepatic metabolism by insulin (2010) (0)
- Regulation of Lipid Metabolism in Drosophila (2007) (0)
- Ran GTPase-Independent and Stereochemical Control of Kinesin-1 and Mitochondrial Motility by Domains of Ran-Binding Protein-2 (2013) (0)
- Growth differentiation factor 15 (GDF-15) as a key regulator of cachexia induced by platinum-based chemotherapy. (2020) (0)
- Opposing roles of Akt1 and Akt2 in the Rac/PAK pathway (2006) (0)
- O1-06-03: Akt functions to regulate the chaperone complex and attenuate Tau degradation (2008) (0)
- Role of PI3Ks and protein kinases in GLUT4 trafficking (2001) (0)
- Retractions and Errata (2009) (0)
- Loss of PIP5KIβ Causes a Defect in Lamellipodia Formation and Shear Resistant Adhesion. (2006) (0)
- Macrophages React to Postprandial Signals and Regulate the Response to Feeding through Akt-mTOR–Dependent Production of IL-10 (2018) (0)
- Akt and mTOR Pathways Differentially Regulate the Development of Natural and Inducible IL-17-Producing CD4+ T Cells (2012) (0)
- Lit Lunch 2_13_15 Damian: (2015) (0)
- Regulation of hepatic lipid metabolism by insulin (2009) (0)
- Abstract 15637: AKT Regulates Cardiomyocyte Homeostasis by Regulating the Expression of the Voltage-Dependent L-Type Ca2+ Channel (Cav1.2) (2013) (0)
- New player in the aerobic glycolysis and liver tumorigenesis – unexplored role of PPARg (2012) (0)
- Epidermal growth factor induced phosphoinositide 3-OH kinase pathway dependent activation of protein kinase B/Akt in human esophageal cancer cell lines (2000) (0)
- Publisher Correction: Targeting hepatic glutaminase activity to ameliorate hyperglycemia (2018) (0)
- sugar/polyol transport facilitators Nomenclature of the GLUT/SLC2A family of (2011) (0)
- Decision letter: Native adiponectin in serum binds to mammalian cells expressing T-cadherin, but not AdipoRs or calreticulin (2019) (0)
- Quantitative analysis of anti-apoptotic function of Akt in Akt 1 and Akt 2 double knock out MEF cells under normal and stressed conditions (2006) (0)
- Retractions and Errata (2009) (0)
- Abstract 3056: Growth differentiation factor 15 (GDF-15) inhibition attenuates platinum-based chemotherapy-induced emesis, anorexia and weight loss and increases survival (2020) (0)
- 644 Selective inhibition of Ras, PI3-kinase and Akt isoforms can radiosensitize human carcinoma cell lines (2004) (0)
- Retractions and Errata (2009) (0)
- Akt/PKB‐sensitive proximal tubular glucose and phosphate transport (2010) (0)
- PI3- KINASE-DEPENDENT PATHWAYS REGULATING GLUT4 TRANSLOCATION (1997) (0)
- GLUT-4 targeting: lessons from insulin-responsive cells (1995) (0)
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What Schools Are Affiliated With Morris J. Birnbaum?
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