Motoharu Seiki

Q: What Schools Are Affiliated With Motoharu Seiki

Motoharu Seiki is affiliated with the following schools: Kanazawa University, University of Tokyo, Stanford University, Osaka University, Autonomous University of Madrid, Kōchi University

Motoharu Seiki's AcademicInfluence.com Rankings

Motoharu Seiki

Biology

#5597

World Rank

#8113

Historical Rank

Molecular Biology

#512

World Rank

#524

Historical Rank

biology Degrees

Download Badge

Biology

Motoharu Seiki's Degrees

PhD Molecular Biology University of Tokyo
Bachelors Biology University of Tokyo

Similar Degrees You Can Earn

Best Online Bachelor's in Biology 2025

Why Is Motoharu Seiki Influential?

(Suggest an Edit or Addition)

(See a Problem?)

Motoharu Seiki's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

A matrix metalloproteinase expressed on the surface of invasive tumour cells (1994) (2655)
Human adult T-cell leukemia virus: complete nucleotide sequence of the provirus genome integrated in leukemia cell DNA. (1983) (1441)
SR alpha promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat (1988) (1232)
Membrane Type 1 Matrix Metalloproteinase Digests Interstitial Collagens and Other Extracellular Matrix Macromolecules* (1997) (953)
Monoclonal integration of human T-cell leukemia provirus in all primary tumors of adult T-cell leukemia suggests causative role of human T-cell leukemia virus in the disease. (1984) (847)
Membrane-Type 1 Matrix Metalloproteinase Cleaves Cd44 and Promotes Cell Migration (2001) (764)
Regulatory mechanism of 92 kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells. (1993) (750)
The Membrane-Anchored MMP Inhibitor RECK Is a Key Regulator of Extracellular Matrix Integrity and Angiogenesis (2001) (689)
Identification of the Second Membrane-type Matrix Metalloproteinase (MT-MMP-2) Gene from a Human Placenta cDNA Library (1995) (505)
MT1‐MMP: A potent modifier of pericellular microenvironment (2006) (502)
Induction of interleukin 2 receptor gene expression by p40x encoded by human T‐cell leukemia virus type 1. (1986) (481)
Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion. (1997) (453)
Evidence for aberrant activation of the interleukin-2 autocrine loop by HTLV-1-encoded p40x and T3/Ti complex triggering (1987) (430)
Membrane-type 1 matrix metalloproteinase: a key enzyme for tumor invasion. (2003) (407)
Homophilic complex formation of MT1‐MMP facilitates proMMP‐2 activation on the cell surface and promotes tumor cell invasion (2001) (400)
Stimulation of 92-kDa Gelatinase B Promoter Activity by ras Is Mitogen-activated Protein Kinase Kinase 1-independent and Requires Multiple Transcription Factor Binding Sites Including Closely Spaced PEA3/ets and AP-1 Sequences (*) (1996) (375)
Activation of a recombinant membrane type 1‐matrix metalloproteinase (MT1‐MMP) by furin and its interaction with tissue inhibitor of metalloproteinases (TIMP)‐2 (1996) (375)
Involvement of Flt-1 tyrosine kinase (vascular endothelial growth factor receptor-1) in pathological angiogenesis. (2001) (365)
CD44 directs membrane‐type 1 matrix metalloproteinase to lamellipodia by associating with its hemopexin‐like domain (2002) (322)
Localization of matrix metalloproteinase 9 (92-kilodalton gelatinase/type IV collagenase = gelatinase B) in osteoclasts: implications for bone resorption. (1995) (321)
Expression of membrane-type matrix metalloproteinase in human gastric carcinomas. (1995) (305)
Significant correlation of monocyte chemoattractant protein‐1 expression with neovascularization and progression of breast carcinoma (2001) (303)
Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro. (1996) (299)
v-Src activates the expression of 92-kDa type IV collagenase gene through the AP-1 site and the GT box homologous to retinoblastoma control elements. A mechanism regulating gene expression independent of that by inflammatory cytokines. (1993) (298)
TIMP-2 Promotes Activation of Progelatinase A by Membrane-type 1 Matrix Metalloproteinase Immobilized on Agarose Beads* (1998) (298)
Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomas. (1997) (297)
Nonspecific integration of the HTLV provirus genome into adult T-cell leukaemia cells (1984) (286)
Activation of the precursor of gelatinase A/72 kda type IV collagenase/MMP‐2 in lung carcinomas correlates with the expression of membrane‐type matrix metalloproteinase (MT‐MMP) and with lymph node metastasis (1995) (284)
The C-terminal Region of Membrane Type Matrix Metalloproteinase Is a Functional Transmembrane Domain Required for Pro-gelatinase A Activation (*) (1995) (282)
Post‐transcriptional regulator (rex) of HTLV‐1 initiates expression of viral structural proteins but suppresses expression of regulatory proteins. (1988) (271)
Cytoplasmic tail–dependent internalization of membrane-type 1 matrix metalloproteinase is important for its invasion-promoting activity (2001) (253)
Identification of membrane-type matrix metalloproteinase-1 as a target of the β-catenin/Tcf4 complex in human colorectal cancers (2002) (251)
Intermolecular Autolytic Cleavage Can Contribute to the Activation of Progelatinase A by Cell Membranes (*) (1995) (247)
Membrane-type matrix metalloproteinase 1 is a gelatinolytic enzyme and is secreted in a complex with tissue inhibitor of metalloproteinases 2. (1996) (245)
Membrane-type matrix metalloproteinases. (1999) (242)
Interaction of HTLV-1 Tax1 with p67SRF causes the aberrant induction of cellular immediate early genes through CArG boxes. (1992) (242)
Expression of genes encoding type IV collagen-degrading metalloproteinases and tissue inhibitors of metalloproteinases in various human tumor cells. (1992) (237)
Functional activation of the long terminal repeat of human T-cell leukemia virus type I by a trans-acting factor. (1985) (236)
Turnover of Focal Adhesions and Cancer Cell Migration (2012) (234)
Transcriptional (p40x) and post-transcriptional (p27x-III) regulators are required for the expression and replication of human T-cell leukemia virus type I genes. (1987) (232)
The cell surface: the stage for matrix metalloproteinase regulation of migration. (2002) (232)
Negative Regulation of Osteoclastogenesis by Ectodomain Shedding of Receptor Activator of NF-κB Ligand* (2006) (231)
Claudin Promotes Activation of Pro-matrix Metalloproteinase-2 Mediated by Membrane-type Matrix Metalloproteinases* (2001) (231)
The Ets‐1 and Ets‐2 transcription factors activate the promoters for invasion‐associated urokinase and collagenase genes in response to epidermal growth factor (1998) (223)
MT1-MMP-dependent control of skeletal stem cell commitment via a β1-integrin/YAP/TAZ signaling axis. (2013) (220)
Expression and tissue localization of membrane-type 1, 2, and 3 matrix metalloproteinases in human astrocytic tumors. (1999) (217)
Membrane-type matrix metalloproteinases (MT-MMPs) in tumor metastasis. (1996) (202)
Cortactin promotes exosome secretion by controlling branched actin dynamics (2016) (202)
Direct evidence that p40x of human T‐cell leukemia virus type I is a trans‐acting transcriptional activator. (1986) (200)
Crosstalk between neovessels and mural cells directs the site-specific expression of MT1-MMP to endothelial tip cells (2007) (199)
HTLV-1 Tax induces expression of various immediate early serum responsive genes. (1991) (199)
Cell surface binding and activation of gelatinase A induced by expression of membrane‐type‐1‐matrix metalloproteinase (MT1‐MMP) (1996) (196)
Implication of collagen type I-induced membrane-type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in the metastatic progression of breast carcinoma. (1997) (190)
Expression of the pX gene of HTLV-I: general splicing mechanism in the HTLV family. (1985) (189)
Human adult T-cell leukemia virus: molecular cloning of the provirus DNA and the unique terminal structure. (1982) (183)
Enhanced production of matrix metalloproteinases and activation of matrix metalloproteinase 2 (gelatinase A) in human gastric carcinomas (1996) (180)
Increased expression of matrix metalloproteinase‐II in experimental liver fibrosis in rats (1995) (174)
MT-MMP, the cell surface activator of proMMP-2 (pro-gelatinase A), is expressed with its substrate in mouse tissue during embryogenesis. (1996) (168)
Membrane Type 4 Matrix Metalloproteinase (MT4-MMP, MMP-17) Is a Glycosylphosphatidylinositol-anchored Proteinase* (1999) (166)
T-cell activation signals and human T-cell leukemia virus type I-encoded p40x protein activate the mouse granulocyte-macrophage colony-stimulating factor gene through a common DNA element (1988) (166)
Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human papillary thyroid carcinomas. (1999) (166)
The detection of human T cell leukemia virus proviral DNA and its application for classification and diagnosis of T cell malignancy. (1984) (162)
A transcriptional enhancer sequence of HTLV‐I is responsible for trans‐activation mediated by p40 chi HTLV‐I. (1986) (161)
Regulation of collagenase-3 expression in human breast carcinomas is mediated by stromal-epithelial cell interactions. (1997) (160)
HTLV type I (U. S. isolate) and ATLV (Japanese isolate) are the same species of human retrovirus. (1984) (158)
Complete nucleotide sequence of the chromosomal gene for human IL-4 and its expression. (1989) (157)
Overexpression of membrane-type matrix metalloproteinase-1 gene induces mammary gland abnormalities and adenocarcinoma in transgenic mice. (2001) (152)
Front-cell-specific expression of membrane-type 1 matrix metalloproteinase and gelatinase A during cohort migration of colon carcinoma cells induced by hepatocyte growth factor/scatter factor. (2000) (151)
Sequence homology of the simian retrovirus genome with human T-cell leukemia virus type I. (1985) (151)
Proteolytic activation of the precursor of membrane type 1 matrix metalloproteinase by human plasmin (1997) (149)
Roles of pericellular proteolysis by membrane type‐1 matrix metalloproteinase in cancer invasion and angiogenesis (2003) (148)
Sequence-specific silencing of MT1-MMP expression suppresses tumor cell migration and invasion: importance of MT1-MMP as a therapeutic target for invasive tumors (2003) (145)
Two cis-acting elements responsible for posttranscriptional trans-regulation of gene expression of human T-cell leukemia virus type I. (1988) (145)
Mutations in two matrix metalloproteinase genes, MMP-2 and MT1-MMP, are synthetic lethal in mice (2004) (140)
Constitutive and Induced CD44 Shedding by ADAM-Like Proteases and Membrane-Type 1 Matrix Metalloproteinase (2004) (139)
Ets-related protein E1A-F can activate three different matrix metalloproteinase gene promoters. (1995) (139)
Membrane‐type 6 matrix metalloproteinase (MT6‐MMP, MMP‐25) is the second glycosyl‐phosphatidyl inositol (GPI)‐anchored MMP (2000) (135)
Monoclonal integration of HTLV‐I proviral DNA in patients with strongyloidiasis (1987) (135)
Cleavage of metastasis suppressor gene product KiSS-1 protein/metastin by matrix metalloproteinases (2003) (133)
Increased expression of membrane type 1‐matrix metalloproteinase in head and neck carcinoma (1997) (133)
Expression of membrane-type matrix metalloproteinase 1 (MT1-MMP) in tumor cells enhances pulmonary metastasis in an experimental metastasis assay. (1996) (132)
IRSp53/Eps8 Complex Is Important for Positive Regulation of Rac and Cancer Cell Motility/Invasiveness (2004) (130)
Induction and stimulation of 92-kDa gelatinase/type IV collagenase production in osteosarcoma and fibrosarcoma cell lines by tumor necrosis factor alpha. (1990) (124)
Membrane-type Matrix Metalloproteinase-1 (MT1-MMP) Is a Processing Enzyme for Human Laminin γ2 Chain* (2005) (124)
Complex regulation of membrane-type matrix metalloproteinase expression and matrix metalloproteinase-2 activation by concanavalin A in MDA-MB-231 human breast cancer cells. (1995) (124)
Membrane Type 1 Matrix Metalloproteinase (MT1-MMP/MMP-14) Cleaves and Releases a 22-kDa Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) Fragment from Tumor Cells* (2006) (121)
Expression of membrane-type 1 matrix metalloproteinase and activation of progelatinase A in human osteoarthritic cartilage. (1997) (120)
p27x-III and p21x-III, proteins encoded by the pX sequence of human T-cell leukemia virus type I. (1985) (119)
Membrane type 1 matrix metalloproteinase is a crucial promoter of synovial invasion in human rheumatoid arthritis. (2009) (118)
Ageladine A: an antiangiogenic matrixmetalloproteinase inhibitor from the marine sponge Agelas nakamurai. (2003) (118)
Anti-invasive activity of ursolic acid correlates with the reduced expression of matrix metalloproteinase-9 (MMP-9) in HT1080 human fibrosarcoma cells. (1996) (118)
Multifunctional roles of MT1-MMP in myofiber formation and morphostatic maintenance of skeletal muscle (2006) (117)
Transcriptional activation of the matrix metalloproteinase-9 gene in an H-ras and v-myc transformed rat embryo cell line (1997) (114)
Membrane-Type Matrix Metalloproteinases (MT-MMPs) in Cell Invasion (1997) (112)
Activation of T cell-derived lymphokine genes in T cells and fibroblasts: effects of human T cell leukemia virus type I p40x protein and bovine papilloma virus encoded E2 protein. (1988) (111)
Processing of a precursor of 72-kilodalton type IV collagenase/gelatinase A by a recombinant membrane-type 1 matrix metalloproteinase. (1996) (111)
New collagenolytic enzymes/cascade identified at the pannus-hard tissue junction in rheumatoid arthritis: destruction from above. (1998) (111)
Characterization of a truncated recombinant form of human membrane type 3 matrix metalloproteinase. (1999) (109)
A single species of pX mRNA of human T-cell leukemia virus type I encodes trans-activator p40x and two other phosphoproteins (1986) (109)
Membrane Type 1 Matrix Metalloproteinase Regulates Collagen-Dependent Mitogen-Activated Protein/Extracellular Signal-Related Kinase Activation and Cell Migration (2004) (108)
Tissue inhibitor of metalloproteinase 1 is a negative regulator of the metastatic ability of a human gastric cancer cell line, KKLS, in the chick embryo. (1993) (108)
Matrix metalloproteinase expression and function during fin regeneration in zebrafish: analysis of MT1-MMP, MMP2 and TIMP2. (2005) (106)
Transformation of Madin-Darby canine kidney (MDCK) epithelial cells by Epstein-Barr virus latent membrane protein 1 (LMP1) induces expression of Ets1 and invasive growth (2000) (106)
Dual expression of matrix metalloproteinase‐2 and membrane‐type 1‐matrix metalloproteinase in fibrotic human livers (1997) (106)
Membrane-type 5 matrix metalloproteinase is expressed in differentiated neurons and regulates axonal growth. (2001) (105)
Role of pericellular proteolysis by membrane-type 1 matrix metalloproteinase in cancer invasion and angiogenesis (2003) (104)
Membrane-type 1 matrix metalloproteinase modulates focal adhesion stability and cell migration. (2006) (103)
Ursolic acid-induced down-regulation of MMP-9 gene is mediated through the nuclear translocation of glucocorticoid receptor in HT1080 human fibrosarcoma cells (1998) (102)
Interferons Inhibit Tumor Necrosis Factor-α-mediated Matrix Metalloproteinase-9 Activation via Interferon Regulatory Factor-1 Binding Competition with NF-κB* (2002) (101)
Tetraspanin CD63 promotes targeting and lysosomal proteolysis of membrane-type 1 matrix metalloproteinase. (2003) (101)
Cell surface collagenolysis requires homodimerization of the membrane-bound collagenase MT1-MMP. (2006) (101)
Identification of gag and env gene products of human T-cell leukemia virus (HTLV). (1984) (101)
MT1-MMP and MMP-2 mRNA expression in human ovarian tumors: possible implications for the role of desmoplastic fibroblasts. (1998) (100)
MT1-MMP correlates with MMP-2 activation potential seen after epithelial to mesenchymal transition in human breast carcinoma cells (1997) (100)
Dual expression of matrix metalloproteinase-2 and membrane-type 1-matrix metalloproteinase in fibrotic human livers. (1998) (98)
Human T-cell leukemia virus type I is a member of the African subtype of simian viruses (STLV). (1986) (97)
Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin β1 (2013) (96)
Role of tissue inhibitor of metalloproteinases-2 (TIMP-2) in regulation of pro-gelatinase A activation catalyzed by membrane-type matrix metalloproteinase-1 (MT1-MMP) in human cancer cells. (1998) (95)
Recent advances in the molecular biology of HTLV-1: trans-activation of viral and cellular genes. (1987) (95)
MT-MMPs play pivotal roles in cancer dissemination (2004) (94)
Dual over‐expression pattern of membrane‐type metalloproteinase‐1 in cancer and stromal cells in human gastrointestinal carcinoma revealed by in situ hybridization and immunoelectron microscopy (1996) (94)
Induction of M(r) 92,000 type IV collagenase expression in a squamous cell carcinoma cell line by fibroblasts. (1995) (94)
CD44 binding through the hemopexin-like domain is critical for its shedding by membrane-type 1 matrix metalloproteinase (2005) (93)
Cloning of a human gene potentially encoding a novel matrix metalloproteinase having a C-terminal transmembrane domain. (1995) (90)
Matrix metalloproteinase 9 (gelatinase B) is expressed in multinucleated giant cells of human giant cell tumor of bone and is associated with vascular invasion. (1996) (89)
Stroma-derived matrix metalloproteinase (MMP)-2 promotes membrane type 1-MMP-dependent tumor growth in mice. (2007) (89)
Enhanced tumor growth and invasiveness in vivo by a carboxyl-terminal fragment of alpha1-proteinase inhibitor generated by matrix metalloproteinases: a possible modulatory role in natural killer cytotoxicity. (1999) (88)
A Membrane Protease Regulates Energy Production in Macrophages by Activating Hypoxia-inducible Factor-1 via a Non-proteolytic Mechanism* (2010) (88)
Cytoplasmic tail of MT1‐MMP regulates macrophage motility independently from its protease activity (2009) (87)
Secondary structure of the human T-cell leukemia virus type 1 rex-responsive element is essential for rex regulation of RNA processing and transport of unspliced RNAs (1990) (86)
Expression and Tissue Localization of Membrane-Types 1, 2, and 3 Matrix Metalloproteinases in Rheumatoid Synovium (2000) (85)
Polyclonal integration of HTLV‐I proviral DNA in lymphocytes from HTLV‐I seropositive individuals: an intermediate state between the healthy carrier state and smouldering ATL (1988) (85)
Activation of matrix metalloproteinase‐2 in human breast cancer cells overexpressing cyclooxygenase‐1 or ‐2 (1999) (85)
Inhibition of metastasis in human gastric cancer cells transfected with tissue inhibitor of metalloproteinase 1 gene in nude mice (1996) (82)
Membrane type 1-matrix metalloproteinase is involved in the formation of hepatocyte growth factor/scatter factor-induced branching tubules in madin-darby canine kidney epithelial cells. (1998) (80)
The second pX product p27 x‐III of HTLV‐1 is required for gag gene expression (1986) (77)
Regulation of matrix metalloproteinase‐2 (MMP‐2) by hepatocyte growth factor/scatter factor (HGF/SF) in human glioma cells: HGF/SF enhances MMP‐2 expression and activation accompanying up‐regulation of membrane type‐1 MMP (1999) (77)
Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human oral squamous cell carcinomas: Implications for lymph node metastasis (2004) (77)
MT1-MMP: an enzyme with multidimensional regulation. (2004) (75)
Network Analysis of the Focal Adhesion to Invadopodia Transition Identifies a PI3K-PKCα Invasive Signaling Axis (2012) (75)
Matrix metalloproteinases and tissue inhibitor of metalloproteinase-2 in fetal rabbit lung. (2000) (73)
Establishment and Validation of Computational Model for MT1-MMP Dependent ECM Degradation and Intervention Strategies (2012) (68)
MT-MMP expression and localisation in human lung and breast cancers (1996) (68)
Cloning of three Caenorhabditis elegans genes potentially encoding novel matrix metalloproteinases. (1998) (68)
Targeting the Warburg Effect That Arises in Tumor Cells Expressing Membrane Type-1 Matrix Metalloproteinase* (2011) (68)
Absence of mechanical allodynia and Aβ‐fiber sprouting after sciatic nerve injury in mice lacking membrane‐type 5 matrix metalloproteinase (2004) (68)
Evidence for the Involvement of MMP14 in MMP2 Processing and Recruitment in Exosomes of Corneal Fibroblasts. (2014) (67)
Human T-cell leukemia virus type 1 Tax activates transcription of the human fra-1 gene through multiple cis elements responsive to transmembrane signals (1993) (64)
The Second Dimer Interface of MT1-MMP, the Transmembrane Domain, Is Essential for ProMMP-2 Activation on the Cell Surface* (2008) (62)
Palmitoylation at Cys574 is essential for MT1‐MMP to promote cell migration (2005) (61)
Membrane‐type 1 MMP (MMP‐14) cleaves at three sites in the aggrecan interglobular domain (1998) (61)
A Novel Protein Associated with Membrane-type 1 Matrix Metalloproteinase Binds p27kip1 and Regulates RhoA Activation, Actin Remodeling, and Matrigel Invasion* (2009) (61)
Production of Membrane-type Matrix Metalloproteinase-1 (MT-MMP-1) in Early Human Placenta: A Possible Role in Placental Implantation? (1998) (60)
Clusterin, an Abundant Serum Factor, Is a Possible Negative Regulator of MT6-MMP/MMP-25 Produced by Neutrophils* (2003) (59)
Furin-independent Pathway of Membrane Type 1-Matrix Metalloproteinase Activation in Rabbit Dermal Fibroblasts* (1999) (57)
Membrane-type 1 Matrix Metalloproteinase Cytoplasmic Tail-binding Protein-1 Is a New Member of the Cupin Superfamily (2004) (57)
Membrane-type 1 matrix metalloproteinase and cell migration. (2003) (56)
Transformation of epithelial Madin-Darby canine kidney cells with p60(v-src) induces expression of membrane-type 1 matrix metalloproteinase and invasiveness. (1998) (56)
Isolation of a mouse MT2‐MMP gene from a lung cDNA library and identification of its product (1997) (55)
Interferons inhibit tumor necrosis factor-alpha-mediated matrix metalloproteinase-9 activation via interferon regulatory factor-1 binding competition with NF-kappa B. (2002) (55)
White matter microglia produce membrane-type matrix metalloprotease, an activator of gelatinase A, in human brain tissues (2004) (55)
Type I Collagen Abrogates the Clathrin-mediated Internalization of Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) via the MT1-MMP Hemopexin Domain* (2006) (54)
Mint3 Enhances the Activity of Hypoxia-inducible Factor-1 (HIF-1) in Macrophages by Suppressing the Activity of Factor Inhibiting HIF-1* (2009) (54)
Identification of a protein (p40x) encoded by a unique sequence pX of human T-cell leukemia virus type I. (1984) (52)
Tumor cell contact mediated transcriptional activation of the fibroblast matrix metalloproteinase-9 gene: involvement of multiple transcription factors including Ets and an alternating purine-pyrimidine repeat (1998) (51)
Detection and characterization of simian retroviruses homologous to human T-cell leukemia virus type I. (1984) (50)
Envelope proteins of human T-cell leukemia virus: expression in Escherichia coli and its application to studies of env gene functions. (1984) (50)
Membrane-type matrix metalloproteinase-1(MT1-MTP) gene is overexpressed in highly invasive hepatocellular carcinomas. (1998) (49)
Identification of the Tax interaction region of serum response factor that mediates the aberrant induction of immediate early genes through CArG boxes by HTLV-I Tax. (1995) (49)
Deficiency of MMP17/MT4-MMP proteolytic activity predisposes to aortic aneurysm in mice. (2015) (49)
Enhancement of membrane-type 1-matrix metalloproteinase (MT1-MMP) production and sequential activation of progelatinase A on human squamous carcinoma cells co-cultured with human dermal fibroblasts (1999) (48)
MT1-MMP plays a critical role in hematopoiesis by regulating HIF-mediated chemokine/cytokine gene transcription within niche cells. (2012) (48)
Matrix metalloproteinase 14 modulates signal transduction and angiogenesis in the cornea. (2016) (46)
Retrovirus from human T-cell leukemia virus type I-associated myelopathy is the same strain as a prototype human T-cell leukemia virus type I. (1990) (46)
Human membrane type‐4 matrix metalloproteinase (MT4‐MMP) is encoded by a novel major transcript: isolation of complementary DNA clones for human and mouse mt4‐mmp transcripts (1999) (45)
Immunohistochemical study of MT-MMP tissue status in gastric carcinoma and correlation with survival analyzed by univariate and multivariate analysis. (1998) (44)
Membrane type 1-matrix metalloproteinase cleaves off the NH2-terminal portion of heparin-binding epidermal growth factor and converts it into a heparin-independent growth factor. (2010) (44)
CDCP1 Regulates the Function of MT1-MMP and Invadopodia-Mediated Invasion of Cancer Cells (2013) (43)
lymphoma type adult T‐cell leukemia—a clinicopathologic study of HTLV related T‐cell type malignant lymphoma (1986) (43)
Identification of CD44 as a cell surface marker for Müller glia precursor cells (2010) (43)
Serum response factor has functional roles both in indirect binding to the CArG box and in the transcriptional activation function of human T-cell leukemia virus type I Tax (1994) (42)
Integrated functions of membrane‐type 1 matrix metalloproteinase in regulating cancer malignancy: Beyond a proteinase (2017) (42)
Tax proteins of human T-cell leukemia virus type 1 and 2 induce expression of the gene encoding erythroid-potentiating activity (tissue inhibitor of metalloproteinases-1, TIMP-1). (1994) (42)
The U5 sequence is a cis-acting repressive element for genomic RNA expression of human T cell leukemia virus type I. (1990) (41)
Critical Role of Transient Activity of MT1-MMP for ECM Degradation in Invadopodia (2013) (41)
HTLV-1 Tax has distinct but overlapping domains for transcriptional activation and for enhancer specificity. (1991) (41)
Competitive disruption of the tumor-promoting function of membrane type 1 matrix metalloproteinase/matrix metalloproteinase-14 in vivo (2005) (41)
Expression of the membrane-type 3 matrix metalloproteinase (MT3-MMP) in human brain tissues (1998) (41)
Hypoxia-Inducible Factor 1 Regulation through Cross Talk between mTOR and MT1-MMP (2013) (41)
Hepatocyte growth factor activator inhibitor type 1 is a suppressor of intestinal tumorigenesis. (2013) (41)
Differentiation-dependent expression of gelatinase B/matrix metalloproteinase-9 in trophoblast cells (1999) (41)
Activation of pro‐MMP‐2 mediated by MT1‐MMP in human salivary gland carcinomas: possible regulation of pro‐MMP‐2 activation by TIMP‐2 (2004) (40)
Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human urothelial carcinomas. (1998) (40)
Calcium influx inhibits MT1‐MMP processing and blocks MMP‐2 activation (1997) (40)
Suppression of matrix metalloproteinase-3 synthesis by interleukin-4 in human articular chondrocytes. (1997) (39)
Cholestatic liver fibrosis and toxin-induced fibrosis are exacerbated in matrix metalloproteinase-2 deficient mice. (2011) (39)
Establishment of an MT4‐MMP‐deficient mouse strain representing an efficient tracking system for MT4‐MMP/MMP‐17 expression in vivo using β‐galactosidase (2007) (39)
Effects of indomethacin on the production of matrix metalloproteinase-3 and tissue inhibitor of metalloproteinases-1 by human articular chondrocytes. (1996) (38)
Expression of laminin 5-γ2 chain in cutaneous squamous cell carcinoma and its role in tumour invasion (2011) (38)
The ERK signaling target RNF126 regulates anoikis resistance in cancer cells by changing the mitochondrial metabolic flux (2016) (38)
Expression of type‐IV collagenases in human tumor cell lines that can form liver colonies in chick embryos (2007) (38)
Ancorinosides B-D, inhibitors of membrane type 1 matrix metalloproteinase (MT1-MMP), from the marine sponge Penares sollasi Thiele. (2001) (38)
Purification and refolding of recombinant human proMMP-7 (pro-matrilysin) expressed in Escherichia coli and its characterization. (1996) (36)
Tyrosine phosphorylation mediates ConA-induced membrane type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in MDA-MB-231 human breast carcinoma cells. (1997) (36)
Human membrane type-2 matrix metalloproteinase is defective in cell-associated activation of progelatinase A. (2000) (35)
Association of the pX gene product of human T-cell leukemia virus type-I with nucleus. (1985) (35)
Ras pathway is required for the activation of MMP-2 secretion and for the invasion of src-transformed 3Y1 (1999) (35)
Effect of novobiocin on initiation of DNA replication in Bacillus subtilis (1979) (34)
Molecular mechanisms of regulation of HTLV-1 gene expression and its association with leukemogenesis. (1989) (34)
Proteolysis of EphA2 Converts It from a Tumor Suppressor to an Oncoprotein. (2015) (33)
Significance of Membrane Type 1 Matrix Metalloproteinase Expression in Breast Cancer (1999) (33)
Dimerization of MT1-MMP during cellular invasion detected by fluorescence resonance energy transfer. (2011) (32)
Expression and localization of membrane type matrix metalloproteinase-1 (MT1-MMP) in trophoblast cells of cultured mouse blastocysts and ectoplacental cones. (1998) (31)
MT4-MMP deficiency increases patrolling monocyte recruitment to early lesions and accelerates atherosclerosis (2018) (30)
Proteolytic activation of heparin‐binding EGF‐like growth factor by membrane‐type matrix metalloproteinase‐1 in ovarian carcinoma cells (2011) (30)
High throughput analysis of proteins associating with a proinvasive MT1‐MMP in human malignant melanoma A375 cells (2009) (30)
Expression of c‐fos gene inhibits proteoglycan synthesis in transfected chondrocyte (1996) (30)
Nucleotide sequence of the protease-coding region in an infectious DNA of simian retrovirus (STLV) of the HTLV-I family. (1986) (30)
Membrane‐type 1 matrix metalloproteinase cytoplasmic tail binding protein‐1 (MTCBP‐1) acts as an eukaryotic aci‐reductone dioxygenase (ARD) in the methionine salvage pathway (2005) (30)
Induction of membrane-type matrix metalloproteinase 1 (MT1-MMP) expression in human fibroblasts by breast adenocarcinoma cells (1997) (30)
The p40x of human T-cell leukemia virus type I is a trans-acting activator of viral gene transcription. (1985) (30)
VIP36 Protein Is a Target of Ectodomain Shedding and Regulates Phagocytosis in Macrophage Raw 264.7 Cells* (2011) (29)
Callysponginol sulfate A, an MT1-MMP inhibitor isolated from the marine sponge Callyspongia truncata. (2003) (29)
MT1-MMP-mediated basement membrane remodeling modulates renal development. (2010) (29)
Deletion of the Mint3/Apba3 Gene in Mice Abrogates Macrophage Functions and Increases Resistance to Lipopolysaccharide-induced Septic Shock* (2011) (29)
Structure of the region of the replication origin of the Bacillus subtilis chromosome (1979) (28)
Shedding of Membrane Type 1 Matrix Metalloproteinase in a Human Breast Carcinoma Cell Line (1999) (27)
Endothelial MT1‐MMP targeting limits intussusceptive angiogenesis and colitis via TSP1/nitric oxide axis (2019) (27)
Tropomodulin 1 expression driven by NF-κB enhances breast cancer growth. (2015) (27)
Development of a new tracking tool for the human monomeric laminin-gamma 2 chain in vitro and in vivo. (2008) (27)
A p27kip1-binding Protein, p27RF-Rho, Promotes Cancer Metastasis via Activation of RhoA and RhoC* (2010) (26)
Different metastatic potentials of ras‐ and src‐transformed BALB/c 3T3 A31 variant cells (1996) (26)
Isolation and structure elucidation of two phosphorylated sterol sulfates, MT1-MMP inhibitors from a marine sponge Cribrochalina sp.: revision of the structures of haplosamates A and B (2001) (26)
Stimulation of the 92-kD type IV collagenase promoter and enzyme expression in human melanoma cells. (1993) (26)
Overexpression of tissue inhibitor of matrix metalloproteinases-1 (TIMP-1) in metastatic MDCK cells transformed by v-src (1999) (26)
Thymic atrophy characteristic in transgenic mice that harbor pX genes of human T-cell leukemia virus type I (1989) (26)
Expression and localization of membrane-type-1 matrix metalloproteinase, CD 44, and laminin-5γ2 chain during colorectal carcinoma tumor progression (2004) (25)
NECAB3 Promotes Activation of Hypoxia-inducible factor-1 during Normoxia and Enhances Tumourigenicity of Cancer Cells (2016) (25)
ZF21 Protein Regulates Cell Adhesion and Motility* (2010) (24)
Replication origin region of Bacillus subtilis chromosome contains two rRNA operons (1983) (24)
Mathematical modeling of invadopodia formation. (2012) (24)
Membrane‐type matrix metalloproteinases (1999) (24)
Basal localization of MT1-MMP is essential for epithelial cell morphogenesis in 3D collagen matrix (2014) (23)
Heat shock suppresses membrane type 1-matrix metalloproteinase production and progelatinase A activation in human fibrosarcoma HT-1080 cells and thereby inhibits cellular invasion. (1999) (22)
Identification of envelope glycoprotein encoded by env gene of human T-cell leukemia virus. (1983) (22)
The proteolytic activity of MT4‐MMP is required for its pro‐angiogenic and pro‐metastatic promoting effects (2012) (22)
Induction of membrane-type matrix metalloproteinase-1 stimulates angiogenic activities of bovine aortic endothelial cells (2004) (22)
Control of metastatic niche formation by targeting APBA3/Mint3 in inflammatory monocytes (2015) (22)
Molecular biology of human T-cell leukemia virus associated with adult T-cell leukemia. (1985) (21)
Ribosomal RNA genes in the replication origin region of Bacillus subtilis chromosome (1982) (21)
Calmodulin antagonists increase the expression of membrane-type-1 matrix metalloproteinase in human uterine cervical fibroblasts. (1998) (21)
Assignment of the human genes for membrane-type-1, -2, and -3 matrix metalloproteinases (MMP14, MMP15, and MMP16) to 14q12.2, 16q12.2-q21, and 8q21, respectively, by in situ hybridization. (1997) (21)
Genetic dissection of proteolytic and non-proteolytic contributions of MT1-MMP to macrophage invasion. (2011) (21)
Adult T-cell leukemia-like disease in monkey naturally infected with simian retrovirus related to human T-cell leukemia virus type I. (1985) (21)
Heat shock-mediated transient increase in intracellular 3′, 5′-cyclic AMP results in tumor specific suppression of membrane type 1-matrix metalloproteinase production and progelatinase A activation (2004) (20)
New insight into the role of MMP14 in metabolic balance (2016) (20)
Mint3-mediated L1CAM expression in fibroblasts promotes cancer cell proliferation via integrin α5β1 and tumour growth (2017) (20)
Synthetic emmprin peptides inhibit tumor cell-fibroblast interaction-stimulated upregulation of MMP-2 and tumor cell invasion. (2011) (20)
Laser scanning-based tissue autofluorescence/fluorescence imaging (LS-TAFI), a new technique for analysis of microanatomy in whole-mount tissues. (2012) (20)
Elevated cyclic AMP suppresses ConA-induced MT1-MMP expression in MDA-MB-231 human breast cancer cells (1998) (20)
Cell Adhesion in Cancer (2012) (19)
Epstein-Barr virus BZLF1 transactivator is a negative regulator of Jun (1992) (19)
Membrane type-matrix metalloproteinase and tumor invasion. (1996) (19)
Two distinct regions form a functional activation domain of the HTLV-1 trans-activator Tax1. (1994) (18)
Comparison of autocrine mechanisms promoting motility in two metastatic cell lines: Human melanoma and ras‐transfected NIH3T3 cells (1991) (18)
Metalloproteinase-Dependent and TMPRSS2-Independent Cell Surface Entry Pathway of SARS-CoV-2 Requires the Furin Cleavage Site and the S2 Domain of Spike Protein (2021) (18)
Clinical aspects of adult T-cell leukemia/lymphoma. (1985) (18)
Mint3 potentiates TLR3/4- and RIG-I–induced IFN-β expression and antiviral immune responses (2016) (18)
Cell-Cell Contact Down-Regulates Expression of Membrane Type MetaIIoproteinase-1 (MT1-MMP) in a Mouse Mammary Gland Epithelial Cell Line (1997) (17)
Spontaneous transformation of human granulosa cell tumours into an aggressive phenotype: a metastasis model cell line (2008) (17)
Specific detection of soluble EphA2 fragments in blood as a new biomarker for pancreatic cancer (2017) (17)
Identification of cis-acting promoter elements that support expression of membrane-type 1 matrix metalloproteinase (MT1-MMP) in v-src transformed Madin–Darby canine kidney cells (2004) (17)
Monoclonal antibodies with defined recognition sequences in the stem region of CD44: detection of differential glycosylation of CD44 between tumor and stromal cells in tissue. (2003) (17)
Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin β1 (2013) (17)
Expression and localization of matrix metalloproteinases (MT1-MMP, MMP-2) and tissue inhibitor of metalloproteinase-2 (TIMP-2) during synepitheliochorial placentation of goats (Capra hircus). (2004) (16)
Organization of the replication-origin region of the Bacillus subtilis chromosome. (1979) (16)
Regulated nucleo‐cytoplasmic shuttling of human aci‐reductone dioxygenase (hADI1) and its potential role in mRNA processing (2007) (16)
Identification of a suppressor sequence for DNA replication in the replication origin region of the Bacillus subtilis chromosome. (1982) (16)
Experimental Metastasis of Oncogene‐transformed NIH 3T3 Cells in Chick Embryo (1992) (15)
ZF21 Protein, a Regulator of the Disassembly of Focal Adhesions and Cancer Metastasis, Contains a Novel Noncanonical Pleckstrin Homology Domain* (2011) (15)
Identification and Characterization of Lutheran Blood Group Glycoprotein as a New Substrate of Membrane-type 1 Matrix Metalloproteinase 1 (MT1-MMP) (2009) (15)
Mint3/Apba3 depletion ameliorates severe murine influenza pneumonia and macrophage cytokine production in response to the influenza virus (2016) (15)
EXOSC9 depletion attenuates P-body formation, stress resistance, and tumorigenicity of cancer cells (2020) (14)
Urinary laminin‐γ2 is a novel biomarker of non‐muscle invasive urothelial carcinoma (2015) (14)
Flow injection analysis for measurement of activity of matrix metalloproteinase-7 (MMP-7). (1997) (14)
Serum monomeric laminin‐γ2 as a novel biomarker for hepatocellular carcinoma (2017) (13)
c-Jun, c-Fos and their family members activate the transcription mediated by three 21-bp repetitive sequences in the HTLV-I long terminal repeat. (1995) (13)
Developmental expression of membrane type 4-matrix metalloproteinase (Mt4-mmp/Mmp17) in the mouse embryo (2017) (13)
Cell Type‐Specific Involvement of Furin in Membrane Type 1 Matrix Metalloproteinase‐Mediated Progelatinase A Activation (1999) (13)
TWO-STEP SANDWICH ENZYME IMMUNOASSAY USING MONOCLONAL ANTIBODIES FOR DETECTION OF SOLUBLE AND MEMBRANE- ASSOCIATED HUMAN MEMBRANE TYPE 1-MATRIX METALLOPROTEINASE (2002) (13)
Expression of membrane-type matrix metalloproteinase-1 in human pancreatic adenocarcinomas (2012) (13)
Selective activation of the proto-oncogene c-jun promoter by the transforming protein v-Rel. (1996) (13)
Impaired alveolization in mice deficient in membrane-type matrix metalloproteinase 1 (MT1-MMP) (2005) (13)
Membrane-Type 4 Matrix Metalloproteinase (MT4-MMP) Modulates Water Homeostasis in Mice (2011) (12)
Structure and function of the region of the replication origin of the Bacillus subtilis chromosome (1981) (12)
Mint3 depletion restricts tumor malignancy of pancreatic cancer cells by decreasing SKP2 expression via HIF-1 (2020) (11)
Unique Biological Activity and Potential Role of Monomeric Laminin-γ2 as a Novel Biomarker for Hepatocellular Carcinoma: A Review (2019) (11)
Detection of the Heterogeneous O-Glycosylation Profile of MT1-MMP Expressed in Cancer Cells by a Simple MALDI-MS Method (2012) (11)
CD44 directs membrane-type 1 matrix metalloproteinase (MT1-MMP) to lamellipodia by associating with its hemopexin-like domain (PEX) (2002) (10)
Mechanism of the gene expression of HTLV-I and its association with ATL. (1986) (10)
Genetic Screening of New Genes Responsible for Cellular Adaptation to Hypoxia Using a Genome-Wide shRNA Library (2012) (9)
Serum Laminin γ2 Monomer as a Diagnostic and Predictive Biomarker for Hepatocellular Carcinoma (2021) (9)
Mint3 depletion-mediated glycolytic and oxidative alterations promote pyroptosis and prevent the spread of Listeria monocytogenes infection in macrophages (2021) (9)
Control and inhibition analysis of complex formation processes (2012) (9)
Mint3 in bone marrow-derived cells promotes lung metastasis in breast cancer model mice. (2017) (9)
ZF21 is a new regulator of focal adhesion disassembly and a potential member of the spreading initiation center (2011) (9)
The Phosphoinositide-Binding Protein ZF21 Regulates ECM Degradation by Invadopodia (2013) (9)
Correction: Critical Role of Transient Activity of MT1-MMP for ECM Degradation in Invadopodia (2013) (9)
CD73 complexes with emmprin to regulate MMP-2 production from co-cultured sarcoma cells and fibroblasts (2019) (9)
Vasoactive Intestinal Peptide Derived From Liver Mesenchymal Cells Mediates Tight Junction Assembly in Mouse Intrahepatic Bile Ducts (2019) (8)
Initiation of DNA replication in Bacillus subtilis (1967) (8)
Matrix metalloproteinase-14 mediates formation of bile ducts and hepatic maturation of fetal hepatic progenitor cells. (2016) (7)
Identification of proteins that associate with integrin α2 by proteomic analysis in human fibrosarcoma HT‐1080 cells (2012) (7)
Dual expression of matrix protease -2 and membrane type I-matrix proteinase in fibrotic human livers (1997) (7)
Epstein‐barr virus lytic cycle spreads via cell fusion in a nasopharyngeal carcinoma hybrid cell line (1994) (7)
Differences between scirrhous and non-scirrhous human gastric carcinomas from the aspect of proMMP-2 activation regulated by TIMP-3 (2004) (7)
Expression of membrane-type 1 matrix metalloproteinase (MT1-MMP) mRNA in trophoblast and endometrial epithelial cell populations of the synepitheliochorial placenta of goats (Capra hircus). (2001) (7)
Pulmonary metastatic lesion of endolymphatic stromal myosis expresses metastasis-related genes but not invasion-related matrix type metalloproteinase. (1997) (7)
Expression of Matrix Metalloproteinase-11 Genes in Placentae and Uteri of Shiba Goats (Capra hircus) (1995) (7)
Development of a fully automated chemiluminescence immunoassay for urine monomeric laminin-γ2 as a promising diagnostic tool of non-muscle invasive bladder cancer (2017) (7)
CELL‐LINE SPECIFIC ACTIVATION OF SV40 TRANSCRIPTIONAL ENHANCER BY p40tax OF HTLV‐1 (1988) (7)
A BALB/c 3T3‐transformed cell line suitable for transfection assay of metastasis‐inducing genes (1997) (6)
Membarne-Type metalloproteinase digests extracellular matrix macromolecules including interstitial collagens (1997) (6)
Advances in Brief Anti-Invasive Activity of Ursolic Acid Correlates with the Reduced Expression of Matrix Metalloproteinase-9 ( MMP-9 ) in HT 1080 Human Fibrosarcoma Cells 1 (2006) (6)
Structural and thermodynamical insights into the binding and inhibition of FIH-1 by the N-terminal disordered region of Mint3 (2021) (6)
Investigation of a MMP-2 Activity-Dependent Anchoring Probe for Nuclear Imaging of Cancer (2014) (5)
NH2‐terminal fragment of ZF21 protein suppresses tumor invasion via inhibiting the interaction of ZF21 with FAK (2020) (5)
[Molecular biology of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs), and the regulation of these genes in tumor tissues]. (1995) (5)
Novel LAMC2 fusion protein has tumor‐promoting properties in ovarian carcinoma (2021) (5)
v-Rel activates the proto-oncogene c-Jun promoter: a correlation with its transforming activity. (1997) (5)
Retrovirus terminology. (1983) (5)
Characterization of simian retrovirus genome related to human T-cell leukemia virus type I. (1984) (5)
Metalloproteinases in Human Invasive Breast Carcinomas (2011) (4)
Report of the Fifth International Conference on Human Retrovirology: Human T-cell Lymphotropic Virus. (1993) (4)
Initiation of DNA replication in Bacillus subtilis (1980) (4)
Signal-Related Kinase Activation and Cell Migration Protein / ExtracellularCollagen-Dependent Mitogen-Activated Membrane Type 1 Matrix Metalloproteinase Regulates (2004) (4)
Structure and function of the region of the replication origin of the Bacillus subtilis chromosome (1981) (4)
Monoclonal integration ofhumanT-cell leukemia provirus inall primary tumorsofadult T-cell leukemia suggests causative role ofhumanT-cell leukemia virus inthedisease (integrated provirus/primary tumorcells/endemic area/Southern blot) (1984) (4)
MPSA short communications (1988) (3)
Activation of metalloproteinase-2 by membrane type metalloproteinase expressed on human mesangial cell membrane. (1996) (3)
Initiation of DNA replication in Bacillus subtilis. IV. The effect of an intercalating dye, ethidium bromide. (1980) (3)
SRotPromoter: anEfficient andVersatile Mammalian cDNA Expression SystemComposedoftheSimian Virus 40Early Promoter andtheR-U5Segment ofHumanT-Cell Leukemia Virus Type1LongTerminal Repeat (1988) (3)
Identification of Proteolytic Cleavage Sites of EphA2 by Membrane Type 1 Matrix Metalloproteinase on the Surface of Cancer Cells. (2018) (3)
Human t‐cell leukemia virus: Causative roles in development of adult t‐cell leukemia and provirus integration into leukemic cell DNA (1986) (3)
Isolation of Highly Migratory and Invasive Cells in Three‐Dimensional Gels (2020) (3)
Inhibition of metastasis in human gastric cancer cells transfected with tissue inhibitor of metalloproteinase 1 gene in nude mice (3)
Simple and cost-effective assay for isolating invasive living cells. (2018) (3)
Expression of Matrix Metalloproteinase-11 (Stromelysin-3) and TIMP-1 Genes in the Placenta and the Uterus during Estrous Cycles and Gestation in the Mouse (1995) (2)
Hepatitis B Virus Utilizes a Retrograde Trafficking Route via the Trans-Golgi Network to Avoid Lysosomal Degradation (2022) (2)
Mint3 is dispensable for pancreatic and kidney functions in mice (2020) (2)
A Novel Protein Associated with Membrane-type 1 Matrix Metalloproteinase Binds p27 kip1 and Regulates RhoA (2009) (2)
[Adult T-cell leukemia virus (ATLV or HTLV) proviral DNA for the classification of T-cell malignancies]. (1984) (2)
Bioactive Marine Metabolites. Part 107. Isolation and Structure Elucidation of Two Phosphorylated Sterol Sulfates, MT1-MMP Inhibitors from a Marine Sponge Cribrochalina sp.: Revision of the Structures of Haplosamates A and B. (2001) (2)
Nakahara memorial lecture. Human T-cell leukemia virus type I: molecular biology and its implications in adult T-cell leukemia. (1984) (2)
[Expression of membrane-type matrix metalloproteinase (MT-MMP) and activation of MMP-2 in lung cancer]. (1995) (2)
Therapy with transcutaneous administration of imiquimod combined with oral administration of sorafenib suppresses renal cell carcinoma growing in an orthotopic mouse model. (2017) (2)
[The role of matrix metalloproteinases in cancer invasion and metastasis]. (1997) (1)
Clinical evaluation of urine laminin‐γ2 monomer as a potent biomarker for non‐muscle invasive bladder cancer (2022) (1)
MT1-MMP Is Required for Hematopoietic Maturation in the BM Niche. (2009) (1)
T-Cell Activation Signals andHumanT-Cell LeukemiaVirusType I-Encoded p40xProtein Activate theMouseGranulocyte- Macrophage Colony-Stimulating Factor Genethrough a Common (1988) (1)
Transient Increase of Intracellular cAMP by Heat Shock Initiates the Suppression of MT1‐MMP Production in Tumor Cells (1998) (1)
Two Step Activation of the Interleukin-2 Autocrine Loop May be Involved in ATL Development (1987) (1)
A Single Species ofpXmRNA ofHumanT-Cell Leukemia Virus TypeIEncodes trans-Activator p40xandTwo OtherPhosphoproteins (1986) (1)
Inhibitory Activities of Peptide-Conformers Originating from Matrix Metalloproteinase-7 against MMPs (1998) (1)
MT4-MMP deficiency increases patrolling monocyte recruitment to early lesions and accelerates atherosclerosis (2018) (1)
Pharmacological inhibition of Mint3 attenuates tumour growth, metastasis, and endotoxic shock (2021) (1)
Control and inhibition analysis of complex formation processes (2012) (1)
[Matrix metalloproteinases; the past, present, and future]. (2003) (1)
Development and Application of a Microplate Assay Method for the Mass Screening of MMP Inhibitors (1999) (1)
HumanT-Cell Leukemia VirusType1 TaxActivates Transcription oftheHumanfra-) Genethrough Multiple cisElements Responsive toTransmembrane Signals (1993) (1)
Synthesis of PRCGVPD-Containing Peptides as MMP-7 Inhibitors (1995) (1)
Proteomic Analysis of Protein Expressed in Odontoblastic Differentiation of Bovine Dental Pulp Cells (2003) (1)
Homophilic complex formation of MT1-matrix metalloproteinase is essential to express collagenolytic activity on the cell surface (2005) (0)
Palmitoylation of MT1-MMP at cysteine 574 in the cytoplasmic tail facilitates its internalisation and modulate cell migration (2004) (0)
[Prevention of tumour invasion]. (2012) (0)
Development of transgenic mice overexpressing MT1-MMP in mammary gland tissue (2000) (0)
[Outline of tumor invasion and metastasis]. (1999) (0)
P4-025 Characterization of primary secretase-like cleavages of alcadein (2006) (0)
Solution structure of the PDZ domain of Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma) (2008) (0)
VIP36 protein is a target of ectodomain shedding and regulates phagocytosis in macrophage raw 264.7 cells. (2014) (0)
151 Unexpected cooperation between uPA and TIMP-2 during myogenic differentiation in vitro (1997) (0)
[Cell adhesion and tumor metastasis]. (1997) (0)
The role of MT1_MMP in renal development (2006) (0)
REGULATION OF MT1-MMP ON CELL SURFACE (2001) (0)
Homophilic complex formation is prerequisite for MT1‐MMP to degrade type‐I collagen on the cell surface (2004) (0)
Function and regulation of MT1-MMP during cell migration (2001) (0)
Studies on the trophoblastic invasion of the endometrium by using cultured mouse blastocysts as a model (1996) (0)
Comparison of Cleavage Site on Oxidized Insulin B-Chain and Synthetic Peptide originating from MMP-2 by the Metalloproteinase purified from Joro Spider, Nephila clavata (1998) (0)
Collagenase-3 (MMP-13) is a recently identified member of the human matrix metalloproteinase gene family that is expressed in breast carcino (2006) (0)
The protease MT4-MMP is essential for maintenance of vascular smooth muscle cell phenotype and vessel homeostasis in vivo (2012) (0)
Solution structure of the first PDZ domain of amyloid beta A4 precursor protein-binding family A, member 1 (2005) (0)
Hepatocyte growth factor activator inhibitor type 1 ( Hai-1 / Spint 1 ) is a suppressor of intestinal tumorigenesis (2013) (0)
ThymicAtrophy Characteristic inTransgenic MiceThatHarborpX GenesofHumanT-Cell Leukemia VirusTypeI (1989) (0)
Advances in Brief Tyrosine Phosphorylation Mediates ConA-induced Membrane Type 1-Matrix Metalloproteinase Expression and Matrix Metalloproteinase-2 Activation in MDA-MB-231 Human Breast Carcinoma Cells 1 (2006) (0)
EXPRESSION OF MT1-MMP AND GELATINASE A (MMP-2) DURING COHORT MIGRATION OF CARCINOMA CELLS. (2001) (0)
Tissue Inhibitor of Metalloproteinase 1 Is a Negative Regulator of the Metastatic Ability of a Human Gastric Cancer Cell Line , KKLS , in the Chick Embryo 1 (1993) (0)
Induction and Enhancement of Lymphokine Gene Expression in Human T Cell Clones Transfected with HTLV-I pX cDNA (1988) (0)
Ancorinosides B-D, Inhibitors of Membrane Type 1 Matrix Metalloproteinase (MT1-MMP), from the Marine Sponge Penares sollasi Thiele (2001) (0)
Lawrence Berkeley National Laboratory Recent Work Title New insight into the role of MMP 14 in metabolic balance Permalink (2016) (0)
The role of MT4_MMP in renal development (2006) (0)
Elucidation of Protein-Protein Interaction Between Mint3, an Intrinsically-disordered Protein, and FIH-1 (2017) (0)
application for classification and diagnosis of T cell malignancy The detection of human T cell leukemia virus proviral DNA and its (2011) (0)
Role of MT1-MMP in Tumor-Stromal Interaction (2009) (0)
Role of cell surface matrix metalloproteinases (2001) (0)
MT1-MMP Regulates Hematopoiesis Through HIF-Mediated Chemo-/Cytokine Release From the Bone Marrow Niche, (2011) (0)
Mint3 depletion-mediated glycolytic and oxidative alterations promote pyroptosis and prevent the spread of Listeria monocytogenes infection in macrophages (2021) (0)
Distinct roles of the hemopexin and the transmembrane domains as dimer interfaces of MT1-MMP on the cell surface (2007) (0)
Regulation of innate immunity through HIF-1 activating factor Mint3 in influenza virus infection (2017) (0)
Role of the HIF activator Mint3 in cancer and inflammatory diseases (2016) (0)
Abstract C65: Membrane type-1 matrix metalloproteinase (MT1-MMP) is a potent regulator of cancer malignant progression through the heparin-binding EGF-like growth factor activation (2013) (0)
MT-MMP and MMP-2 activation by vimentin-positive human breast cancer cell lines indicative of an EMT-like transition. (1996) (0)
139 – Membrane-type matrix metalloproteinase 3 (2004) (0)
Serum Monomeric Laminin-Î"2 as a Novel Biomarker for Hepatocellular Carcinoma (2017) (0)
Tokuda Akihiro Tomida Shinya Toyokuni Hitoshi Tsuda Shoichiro Tsugane Tatsuhiko Tsunoda Heiichiro Udono Koji Ueda Yoshimasa Uehara Hiroo Ueno Kazuo Umezawa Toshikazu Ushijima Toshihiko Wakabayashi Kenji Wakai Tetsuro Watabe (2016) (0)
Adenocarcinoma in Transgenic Mice Gene Induces Mammary Gland Abnormalities and Matrix Metalloproteinase-1 Membrane-type Overexpression of Updated Version (2001) (0)
MT1-MMP Plays a Critical Role In the Modulation of Hematopoiesis. (2010) (0)
, Takeharu Motility ZF 21 Protein Regulates Cell Adhesion and Cell (2010) (0)
天然変性蛋白質Mint3とFIH‐1の相互作用解析におけるH/D交換質量分析法の適用 (2017) (0)
Study on Peptides Inhibiting the Activation of Gelatinase A (MMP-2) (2002) (0)
Regulation of Colkzgenase-3 Expression in Human Breast Carcinomas Is Mediated by Stromal-Epithelial Cell Interactions 1 (2006) (0)
Comparison of Substrate Specificity of Matrix Metalloproteinases by Using Fragment Peptides Originating from MMP-2 (2000) (0)
New metalloprotease and coding dna for (1994) (0)
[Regulation of HTLV-1 gene expression and its relevance to proliferation of the infected cells]. (1989) (0)
Knockout Mice of Matrix Metalloproteinase Genes (2003) (0)
[Expression of matrix metalloproteinases in tumor cells]. (1993) (0)
Development of a fully automated chemiluminescence immunoassay for urine monomeric laminin-γ2 as a promising diagnostic tool of non-muscle invasive bladder cancer (2017) (0)
The molecular biology of human T cell leukemia virus and its roles in leukemogenesis of adult T cell leukemia. (1985) (0)
Identification of New Ca^ Binding Site on Membrane Type Matrix Metalloproteinases by Using Synthetic Fragment Peptides (2002) (0)
Binding mechanism underlying FIH-1 suppression caused by the N-terminal disordered region of Mint3 (2021) (0)
Patterns of Expression of MT-MMP-1 in Cultured Mouse Mammary Gland Epithelial Cell Line, HC11 (1996) (0)
Homology Cancer Metastasis , Contains a Novel Disassembly of Focal Adhesions and ZF 21 Protein , a Regulator of the Molecular Bases of Disease (2011) (0)
Involvement of Human Retrovirus in Specific T-Cell Leukemia (1987) (0)
EXOSC9 depletion attenuates P-body formation, stress resistance, and tumorigenicity of cancer cells (2020) (0)
repeat.leukemia virus type 1 long terminal promoter and the R-U5 segment of human composed of the simian virus 40 early mammalian cDNA expression system SR alpha promoter: an efficient and versatile (2013) (0)
Successful Conclusion of the 8th PPCTSS (2009) (0)
Abstract 399: Deletion of the Mint3 gene in mice abrogates macrophage functions and increases resistance to cancer metastasis (2012) (0)
Membrane-type 1 matrix metalloproteinase modulates focal adhension stability and cell migration (2009) (0)
VIP36 protein is a target of ectodomain shedding and regulates phagocytosis in macrophage Raw 264.7 cells. (2012) (0)
Investigation of mechanism of Membrane-Type 1 Matrix Metalloprotease (MT1-MMP) (1998) (0)
SerumResponse Factor HasFunctional RolesbothinIndirect Binding totheCArGBoxandintheTranscriptional Activation Function of HumanT-Cell Leukemia Virus TypeITax (1994) (0)
p 27 XIII and p 21 x-" " ' , proteins encoded by the pX sequence of human T-cell leukemia virus type I ( pX gene products / overlapping gene / nuclear localization / transactivation ) (0)
MT1-MMP in human rheumatoid arthritis (2009) (0)
IMPAIRED BONE AND TENDON FORMATION IN MICE LACKING MEMBRANETYPE MATRIX METALLOPROTEINASE 1 (MT1-MMP) (2001) (0)
Preface: Membrane-associated proteases (2003) (0)

This paper list is powered by the following services:

What Schools Are Affiliated With Motoharu Seiki?

Motoharu Seiki is affiliated with the following schools:

Motoharu Seiki's Academic­Influence.com Rankings