Nancy Hall Colburn
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Biology
Nancy Hall Colburn's Degrees
- PhD Molecular Biology University of California, Berkeley
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(Suggest an Edit or Addition)Nancy Hall Colburn's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer (2008) (1830)
- MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene (2008) (699)
- S6K1- and ßTRCP-Mediated Degradation of PDCD4 Promotes Protein Translation and Cell Growth (2006) (592)
- The Transformation Suppressor Pdcd4 Is a Novel Eukaryotic Translation Initiation Factor 4A Binding Protein That Inhibits Translation (2003) (467)
- Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion. (1999) (404)
- Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells. (1994) (398)
- S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth. (2006) (343)
- Tumour promoter induces anchorage independence irreversibly (1979) (295)
- Phorbol esters stimulate DNA synthesis and ornithine decarboxylase activity in mouse epidermal cell cultures (1976) (263)
- Correlation of anchorage-independent growth with tumorigenicity of chemically transformed mouse epidermal cells. (1978) (262)
- Differentially expressed protein Pdcd4 inhibits tumor promoter-induced neoplastic transformation. (1999) (258)
- Activator protein 1 (AP-1)– and nuclear factor κB (NF-κB)–dependent transcriptional events in carcinogenesis (2000) (241)
- p53 translocation to mitochondria precedes its nuclear translocation and targets mitochondrial oxidative defense protein-manganese superoxide dismutase. (2005) (239)
- Inhibitors of both nuclear factor-kappaB and activator protein-1 activation block the neoplastic transformation response. (1997) (228)
- p130/pRb2 has growth suppressive properties similar to yet distinctive from those of retinoblastoma family members pRb and p107. (1994) (228)
- AP1/jun function is differentially induced in promotion-sensitive and resistant JB6 cells. (1989) (217)
- Epidermal expression of the translation inhibitor programmed cell death 4 suppresses tumorigenesis. (2005) (216)
- Shortage of mitogen-activated protein kinase is responsible for resistance to AP-1 transactivation and transformation in mouse JB6 cells. (1998) (215)
- TIMP-3 induces cell death by stabilizing TNF-alpha receptors on the surface of human colon carcinoma cells. (1997) (210)
- Anthocyanidins inhibit activator protein 1 activity and cell transformation: structure-activity relationship and molecular mechanisms. (2003) (205)
- A Novel Function of the MA-3 Domains in Transformation and Translation Suppressor Pdcd4 Is Essential for Its Binding to Eukaryotic Translation Initiation Factor 4A (2004) (199)
- Loss of programmed cell death 4 expression marks adenoma‐carcinoma transition, correlates inversely with phosphorylated protein kinase B, and is an independent prognostic factor in resected colorectal cancer (2007) (197)
- Tumorigenesis Suppressor Pdcd4 Down-Regulates Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 Expression To Suppress Colon Carcinoma Cell Invasion (2006) (196)
- A novel transformation suppressor, Pdcd4, inhibits AP-1 transactivation but not NF-κB or ODC transactivation (2001) (193)
- Dissociation of mitogenesis and late-stage promotion of tumor cell phenotype by phorbol esters: mitogen-resistant variants are sensitive to promotion. (1981) (181)
- The role of AP-1, NF-κB and ROS/NOS in skin carcinogenesis: The JB6 model is predictive (2004) (173)
- Inhibition of tumor promoter-induced transformation by retinoids that transrepress AP-1 without transactivating retinoic acid response element. (1996) (167)
- Pdcd4 suppresses tumor phenotype in JB6 cells by inhibiting AP-1 transactivation (2003) (166)
- An infrequent point mutation of the p53 gene in human nasopharyngeal carcinoma. (1992) (162)
- Tumor suppressor Pdcd4 inhibits invasion/intravasation and regulates urokinase receptor (u-PAR) gene expression via Sp-transcription factors (2007) (162)
- Suppression of in vivo tumor growth and induction of suspension cell death by tissue inhibitor of metalloproteinases (TIMP)-3. (1996) (160)
- Downregulation of Pdcd4 by mir-21 facilitates glioblastoma proliferation in vivo. (2011) (159)
- Translation inhibitor Pdcd4 is targeted for degradation during tumor promotion. (2008) (148)
- Promising molecular targets for cancer prevention: AP-1, NF-κB and Pdcd4 (2003) (148)
- AP-1 a target for cancer prevention. (2007) (141)
- Role of reactive oxygen in tumor promotion: implication of superoxide anion in promotion of neoplastic transformation in JB-6 cells by TPA. (1985) (135)
- Characterization of programmed cell death 4 in multiple human cancers reveals a novel enhancer of drug sensitivity. (2004) (132)
- Molecular cloning of five messenger RNAs differentially expressed in preneoplastic or neoplastic JB6 mouse epidermal cells: one is homologous to human tissue inhibitor of metalloproteinases-3. (1994) (132)
- Expression of dominant negative Jun inhibits elevated AP-1 and NF-κB transactivation and suppresses anchorage independent growth of HPV immortalized human keratinocytes (1998) (131)
- Fra-1 a target for cancer prevention or intervention. (2006) (130)
- Insufficient p65 phosphorylation at S536 specifically contributes to the lack of NF-kappaB activation and transformation in resistant JB6 cells. (2004) (126)
- Expression of dominant negative Erk2 inhibits AP-1 transactivation and neoplastic transformation (1998) (126)
- Transactivation of Fra-1 and Consequent Activation of AP-1 Occur Extracellular Signal-Regulated Kinase Dependently (2002) (124)
- A dominant negative mutant of jun blocking 12‐O‐tetradecanoylphorbol‐13‐acetate–induced invasion in mouse keratinocytes (1997) (122)
- Activator protein 1 (AP-1)- and nuclear factor kappaB (NF-kappaB)-dependent transcriptional events in carcinogenesis. (2000) (122)
- Inhibition of AP‐1 and NF‐κB by manganese‐containing superoxide dismutase in human breast cancer cells (1998) (117)
- Comparison of two-stage epidermal carcinogenesis initiated by 7,12-dimethylbenz(a)anthracene or N-methyl-N'-nitro-N-nitrosoguanidine in newborn and adult SENCAR and BALB/c mice. (1981) (114)
- Bioactive Food Components, Inflammatory Targets, and Cancer Prevention (2009) (110)
- Sulfiredoxin–Peroxiredoxin IV axis promotes human lung cancer progression through modulation of specific phosphokinase signaling (2011) (101)
- Expression of dominant negative c-jun inhibits ultraviolet B-induced squamous cell carcinoma number and size in an SKH-1 hairless mouse model. (2003) (98)
- Fluorescence endoscopic detection of murine colitis-associated colon cancer by topically applied enzymatically rapid-activatable probe (2012) (96)
- Resveratrol prevents tumorigenesis in mouse model of Kras activated sporadic colorectal cancer by suppressing oncogenic Kras expression. (2014) (95)
- Early superoxide dismutase-sensitive event promotes neoplastic transformation in mouse epidermal JB6 cells. (1988) (94)
- Vanadate-induced activation of activator protein-1: role of reactive oxygen species. (1999) (94)
- Consumption of a legume-enriched, low-glycemic index diet is associated with biomarkers of insulin resistance and inflammation among men at risk for colorectal cancer. (2010) (90)
- Histone Deacetylase Inhibition Down-Regulates Cyclin D1 Transcription by Inhibiting Nuclear Factor-κB/p65 DNA Binding (2005) (90)
- An integrated understanding of the physiological response to elevated extracellular phosphate (2013) (89)
- Programmed Cell Death-4 Tumor Suppressor Protein Contributes to Retinoic Acid–Induced Terminal Granulocytic Differentiation of Human Myeloid Leukemia Cells (2007) (88)
- Induced expression of dominant‐negative c‐jun downregulates NFκB and AP‐1 target genes and suppresses tumor phenotype in human keratinocytes (2000) (87)
- Aerosol delivery of urocanic acid–modified chitosan/programmed cell death 4 complex regulated apoptosis, cell cycle, and angiogenesis in lungs of K-ras null mice (2006) (86)
- Berberine regulates AMP‐activated protein kinase signaling pathways and inhibits colon tumorigenesis in mice (2015) (86)
- Transformation reversion induced in JB6 RT101 cells by AP-1 inhibitors. (1995) (85)
- Programmed Cell Death 4 inhibits breast cancer cell invasion by increasing Tissue Inhibitor of Metalloproteinases-2 expression (2009) (85)
- Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress. (2005) (80)
- Chemopreventive activity of plant flavonoid isorhamnetin in colorectal cancer is mediated by oncogenic Src and β-catenin. (2013) (76)
- Sulfiredoxin is an AP-1 target gene that is required for transformation and shows elevated expression in human skin malignancies (2008) (76)
- Structural Basis for Inhibition of Translation by the Tumor Suppressor Pdcd4 (2006) (75)
- Elevated Phosphate Activates N-ras and Promotes Cell Transformation and Skin Tumorigenesis (2010) (71)
- A family of mitogen-activated protein kinase-related proteins interacts in vivo with activator protein-1 transcription factor. (1994) (68)
- Maspin gene expression in tumor suppression induced by overexpressing manganese-containing superoxide dismutase cDNA in human breast cancer cells. (1998) (67)
- Interleukin-6 as a Potential Indicator for Prevention of High-Risk Adenoma Recurrence by Dietary Flavonols in the Polyp Prevention Trial (2010) (67)
- Nasopharyngeal carcinoma shows no detectable retinoblastoma susceptibility gene alterations. (1993) (66)
- Depression of catalase gene expression after immortalization and transformation of mouse liver cells. (1993) (65)
- Pdcd4 repression of lysyl oxidase inhibits hypoxia-induced breast cancer cell invasion (2010) (64)
- STAT2 Contributes to Promotion of Colorectal and Skin Carcinogenesis (2010) (63)
- Progressive elevation of ap-1 activity during preneoplastic-to-neoplastic progression as modeled in mouse jb6 cell variants. (1995) (62)
- Cryptotanshinone, a Stat3 inhibitor, suppresses colorectal cancer proliferation and growth in vitro (2015) (61)
- Promising molecular targets for cancer prevention: AP-1, NF-kappa B and Pdcd4. (2003) (60)
- A High Legume Low Glycemic Index Diet Improves Serum Lipid Profiles in Men (2010) (60)
- Molecular Cloning of Mouse Tissue Inhibitor of Metalloproteinases-3 and Its Promoter (1995) (60)
- AP-1, NF-kappa-B, and ERK activation thresholds for promotion of neoplastic transformation in the mouse epidermal JB6 model. (2002) (59)
- The binding of beta-propiolactone to mouse skin DNA in vivo; its correlation with tumor-initiating activity. (1966) (58)
- Involvement of Ras/Raf/AP-1 in BMP-4 signaling during Xenopus embryonic development. (1996) (58)
- Nitric oxide prodrug JS-K inhibits ubiquitin E1 and kills tumor cells retaining wild-type p53 (2009) (57)
- Cancer stem cells: potential target for bioactive food components. (2012) (57)
- Aerosol Delivery of Glucosylated Polyethylenimine/Phosphatase and Tensin Homologue Deleted on Chromosome 10 Complex Suppresses Akt Downstream Pathways in the Lung of K-ras Null Mice (2004) (56)
- Dietary Cooked Navy Beans and Their Fractions Attenuate Colon Carcinogenesis in Azoxymethane-Induced Ob/Ob Mice (2008) (56)
- Mutational analysis of the DEAD-box RNA helicase eIF4AII characterizes its interaction with transformation suppressor Pdcd4 and eIF4GI. (2005) (56)
- Genes and Signal Transduction in Multistage Carcinogenesis (1989) (54)
- Have tumor suppressor PDCD4 and its counteragent oncogenic miR-21 gone rogue? (2010) (54)
- A dominant negative c-jun specifically blocks okadaic acid-induced skin tumor promotion. (2002) (53)
- Diallyl Disulfide (DADS), a Constituent of Garlic, Inactivates NF-κB and Prevents Colitis-Induced Colorectal Cancer by Inhibiting GSK-3β (2016) (53)
- Dominant-negative c-Jun (TAM67) target genes: HMGA1 is required for tumor promoter-induced transformation (2004) (52)
- Dosage‐dependent dominance over wild‐type p53 of a mutant p53 isolated from nasopharyngeal carcinoma 1 (1993) (52)
- A cell culture assay for tumor-promoter-dependent progression toward neoplastic phenotype: detection of tumor promoters and promotion inhibitors. (1980) (52)
- Progression toward tumor cell phenotype is enhanced by overexpression of a mutant p53 tumor-suppressor gene isolated from nasopharyngeal carcinoma. (1993) (52)
- Responses of Preneoplastic Epidermal Cells to Tumor Promoters and Growth Factors: Use of Promoter‐Resistant Variants for Mechanism Studies (1982) (52)
- Elevated inorganic phosphate stimulates Akt-ERK1/2-Mnk1 signaling in human lung cells. (2006) (51)
- No point mutation of ha‐ras or p53 genes expressed in preneoplastic‐to‐neoplastic progression as modeled in mouse JB6 cell variants (1993) (50)
- The in Vivo Binding of β-Propiolactone to Mouse Skin DNA, RNA, and Protein (1968) (48)
- PCR-direct sequencing of a GC-rich region by inclusion of 10% DMSO: application to mouse c-jun. (1993) (48)
- AP-1/Jun Is Required for Early Xenopus Development and Mediates Mesoderm Induction by Fibroblast Growth Factor but Not by Activin (*) (1996) (47)
- Effect of ceramide on intracellular glutathione determines apoptotic or necrotic cell death of JB6 tumor cells. (2000) (47)
- Nitric oxide does not mediate but inhibits transformation and tumor phenotype. (2003) (47)
- The role of AP-1, NF-кB and ROS/ NOS in skin carcinogenesis: The JB6 model is predictive (2002) (47)
- Inhibition by actinomycin D of DNA and RNA synthesis and of skin carcinogenesis initiated by 7,12-dimethylbenz[a]anthracene or beta-propiolactone. (1968) (47)
- IN VIVO REACTIONS OF β‐PROPIOLACTONE (1969) (47)
- Acquisition of a growth-inhibitory response to phorbol ester involves DNA damage. (1992) (47)
- Does telomere shortening drive selection for p53 mutation in human cancer? (1995) (47)
- Tumor suppressor PDCD4 inhibits NF-κB-dependent transcription in human glioblastoma cells by direct interaction with p65. (2014) (46)
- Role of cytoskeleton changes and expression of the H-ras oncogene during promotion of neoplastic transformation in mouse epidermal JB6 cells. (1986) (46)
- STAT3 activation is required for interleukin-6 induced transformation in tumor-promotion sensitive mouse skin epithelial cells (2002) (46)
- Cyclic AMP-elevating agents inhibit proliferation of keratinizing guinea pig epidermal cells. (1974) (45)
- Decrease of epidermal histidase activity by tumor-promoting phorbol esters. (1975) (44)
- Plasma Cytokines as Potential Response Indicators to Dietary Freeze-Dried Black Raspberries in Colorectal Cancer Patients (2012) (44)
- Transformation nonresponsive cells owe their resistance to lack of p65/nuclear factor-kappaB activation. (2001) (44)
- JNK/AP-1 pathway is involved in tumor necrosis factor-alpha induced expression of vascular endothelial growth factor in MCF7 cells. (2009) (44)
- Dominant-negative activator protein 1 (TAM67) targets cyclooxygenase-2 and osteopontin under conditions in which it specifically inhibits tumorigenesis. (2007) (43)
- Aerosol-delivered programmed cell death 4 enhanced apoptosis, controlled cell cycle and suppressed AP-1 activity in the lungs of AP-1 luciferase reporter mice (2007) (43)
- Tumor suppressor Pdcd4attenuates Sin1 translation to inhibit invasion in colon carcinoma (2017) (43)
- Transcriptional Regulation of CRD-BP by c-myc: Implications for c-myc Functions. (2010) (42)
- The binding of beta-propiolactone and some related alkylating agents to DNA, RNA, and protein of mouse skin; relation between tumor-initiating power of alkylating agents and their binding to DNA. (1968) (41)
- Cryptocaryols A-H, α-pyrone-containing 1,3-polyols from Cryptocarya sp. implicated in stabilizing the tumor suppressor Pdcd4. (2011) (41)
- Phorbol diester and epidermal growth factor receptors in 12-O-tetradecanoylphorbol-13-acetate-resistant and -sensitive mouse epidermal cells. (1982) (41)
- Lack of suppression of tumor cell phenotype by overexpression of TIMP-3 in mouse JB6 tumor cells identification of a transfectant with increased tumorigenicity and invasiveness. (1996) (40)
- Protection against human papillomavirus type 16‐E7 oncogene‐induced tumorigenesis by in vivo expression of dominant‐negative c‐jun † (2002) (39)
- The AP-1 transcription factor regulates postnatal mammary gland development. (2006) (39)
- Monitoring of tumor promotion and progression in a mouse model of inflammation-induced colon cancer with magnetic resonance colonography. (2009) (38)
- RETINOIDS INHIBIT PROMOTER‐DEPENDENT PRENEOPLASTIC PROGRESSION IN MOUSE EPIDERMAL CELL LINES (1981) (38)
- Conformationally constrained analogues of diacylglycerol. 29. Cells sort diacylglycerol-lactone chemical zip codes to produce diverse and selective biological activities. (2008) (37)
- Actinopolysporins A-C and tubercidin as a Pdcd4 stabilizer from the halophilic actinomycete Actinopolyspora erythraea YIM 90600. (2011) (37)
- Inflammation-induced loss of Pdcd4 is mediated by phosphorylation-dependent degradation. (2011) (37)
- Tumor-promoting effects of di(2-ethylhexyl)phthalate in JB6 mouse epidermal cells and mouse skin. (1985) (37)
- Erioflorin Stabilizes the Tumor Suppressor Pdcd4 by Inhibiting Its Interaction with the E3-ligase β-TrCP1 (2012) (37)
- Tumor promoter produces anchorage independence in mouse epidermal cells by an induction mechanism. (1980) (36)
- Tumor promoter induces high mobility group HMG-Y protein expression in transformation-sensitive but not -resistant cells (1998) (36)
- c‐jun and multistage carcinogenesis: Association of overexpression of introduced c‐jun with progression toward a neoplastic endpoint in mouse JB6 cells sensitive to tumor promoter‐induced transformation (1995) (34)
- Inflammation-Associated Serum and Colon Markers as Indicators of Dietary Attenuation of Colon Carcinogenesis in ob/ob Mice (2009) (33)
- AP-1 transrepressing retinoic acid does not deplete coactivators or AP-1 monomers but may target specific Jun or Fos containing dimers (2002) (33)
- Phorbol ester-induced anchorage independence and its antagonism by retinoic acid correlates with altered expression of specific glycoproteins. (1981) (32)
- The heavy metal cadmium induces valosin-containing protein (VCP)-mediated aggresome formation. (2008) (31)
- Quassinoid inhibition of AP-1 function does not correlate with cytotoxicity or protein synthesis inhibition. (2009) (31)
- Transfer of Sensitivity to Tumor Promoters by Transfection of DNA from Sensitive into Insensitive Mouse JB6 Epidermal Cells (1983) (31)
- C-JUN/AP-1 as possible mediators of tumor necrosis factor-alpha-induced apoptotic response in mouse JB6 tumor cells. (1995) (31)
- Identification and monitoring of metabolite markers of dry bean consumption in parallel human and mouse studies. (2015) (29)
- Noninvasive Detection of Candidate Molecular Biomarkers in Subjects with a History of Insulin Resistance and Colorectal Adenomas (2009) (29)
- Studies of the reaction of β-propiolactone with deoxyguanosine and related compounds☆ (1965) (28)
- Differential transformation efficiency but not AP-1 induction under anchorage-dependent and -independent conditions. (1994) (28)
- Specific binding of transforming growth factor correlates with promotion of anchorage independence in EGF receptorless mouse JB6 cells. (1981) (28)
- Tumor-promoting phorbol esters inhibit procollagen synthesis at a pretranslational level in JB-6 mouse epidermal cells (1983) (28)
- Benzoyl peroxide promotion of transformation of JB6 mouse epidermal cells: inhibition by ganglioside GT but not retinoic acid. (1985) (28)
- Growth factors, tumor promoters and cancer genes (1988) (28)
- Protein kinase C and its substrates in tumor promoter-sensitive and -resistant cells. (1988) (27)
- Tumor promoter-induced sulfiredoxin is required for mouse skin tumorigenesis. (2014) (27)
- Differential expression of an 80-kDa protein kinase C substrate in preneoplastic and neoplastic mouse JB6 cells. (1989) (26)
- Ganglioside changes induced by tumor promoters in promotable JB6 mouse epidermal cells: antagonism by an antipromoter. (1982) (26)
- The Untapped Potential of Genetically Engineered Mouse Models in Chemoprevention Research: Opportunities and Challenges (2008) (26)
- Microwave-based reaction screening: tandem retro-Diels-Alder/Diels-Alder cycloadditions of o-quinol dimers. (2011) (26)
- Targeting of Noncanonical Wnt5a Signaling by AP-1 Blocker Dominant-Negative Jun When It Inhibits Skin Carcinogenesis. (2012) (25)
- Differential functional significance of AP-1 binding sites in the promoter of the gene encoding mouse tissue inhibitor of metalloproteinases-3. (1997) (24)
- Role of 3′UTRs in the Translation of mRNAs Regulated by Oncogenic eIF4E—A Computational Inference (2009) (24)
- Loss of sulfiredoxin renders mice resistant to azoxymethane/dextran sulfate sodium-induced colon carcinogenesis. (2013) (24)
- Gene regulation and genetic susceptibility to neoplastic transformation: AP-1 and p80 expression in JB6 cells. (1991) (23)
- Targeting the Activator Protein 1 Transcription Factor for the Prevention of Estrogen Receptor–Negative Mammary Tumors (2008) (23)
- Specific methylation events contribute to the transcriptional repression of the mouse tissue inhibitor of metalloproteinases-3 gene in neoplastic cells. (1999) (23)
- A paracrine signal mediates the cell transformation response to low dose gamma radiation in JB6 cells (2005) (22)
- Linoleic acid metabolite suppresses skin inflammation and tumor promotion in mice: possible roles of programmed cell death 4 induction. (2009) (21)
- Serum cytokine concentrations, flavonol intake and colorectal adenoma recurrence in the Polyp Prevention Trial (2010) (21)
- Grassypeptolides F and G, cyanobacterial peptides from Lyngbya majuscula. (2011) (21)
- Impact of dietary components on NK and Treg cell function for cancer prevention (2015) (21)
- Tumor-promoter-resistant cells lack trisialoganglioside response. (1982) (21)
- A High-Throughput Cell-Based Assay to Identify Specific Inhibitors of Transcription Factor AP-1 (2007) (21)
- A selective small-molecule nuclear factor-κB inhibitor from a high-throughput cell-based assay for “activator protein-1 hits” (2009) (21)
- Suppression of p65 phosphorylation coincides with inhibition of IkappaBalpha polyubiquitination and degradation. (2005) (20)
- Genes and signal transduction in tumor promotion: conclusions from studies with promoter resistant variants of JB-6 mouse epidermal cells. (1985) (20)
- Targeting Transcription Factors for Cancer Prevention—the Case of Nrf2 (2008) (20)
- Inhibition by tumor-promoting phorbol esters of procollagen synthesis in promotable JB6 mouse epidermal cells. (1982) (19)
- Histone Deacetylase Inhibition Down-Regulates Cyclin D 1 Transcription by Inhibiting Nuclear Factor-K B / p 65 DNA Binding (2005) (19)
- Preferential oxidation of cell surface sialic acid by periodate leads to promotion of transformation in JB6 cells. (1984) (19)
- Decreased expression of manganese superoxide dismutase mRNA and protein after immortalization and transformation of mouse liver cells. (1993) (19)
- Inhibitors of the oncogenic transcription factor AP-1 from Podocarpus latifolius. (2011) (19)
- Induction of anchorage-independent growth of JB6 mouse epidermal cells by 1 alpha,25-dihydroxyvitamin D3. (1986) (18)
- Extracellular calcium requirement for promotion of transformation in JB6 cells. (1986) (18)
- Tumor promoter benzoyl peroxide induces sulfhydryl oxidation in protein kinase C: its reversibility is related to the cellular resistance to peroxide-induced cytotoxicity. (1999) (17)
- A high-legume low-glycemic index diet reduces fasting plasma leptin in middle-aged insulin-resistant and -sensitive men (2011) (16)
- Discrimination between nonmalignant and malignant cells by combinations of IFN-gamma and IFN-alpha/beta. (1984) (15)
- Development of a High-Throughput Cell-Based Reporter Assay to Identify Stabilizers of Tumor Suppressor Pdcd4 (2010) (15)
- Tricyclic Guanidine Alkaloids from the Marine Sponge Acanthella cavernosa that Stabilize the Tumor Suppressor PDCD4 (2014) (15)
- Programmed cell death 4 (PDCD4): a novel player in ethanol-mediated suppression of protein translation in primary cortical neurons and developing cerebral cortex. (2013) (15)
- Tumor promoter-induced ornithine decarboxylase gene expression occurs independently of AP-1 activation (1999) (15)
- Nucleocytoplasmic shuttling of valosin-containing protein (VCP/p97) regulated by its N domain and C-terminal region. (2015) (14)
- DNA sequences in human nasopharyngeal carcinoma cells that specify susceptibility to tumor promoter-induced neoplastic transformation. (1987) (14)
- Four-day duration of tumor promoter exposure required to transform JB6 promotion-sensitive cells to anchorage independence. (1988) (14)
- Characterization of pomiferin triacetate as a novel mTOR and translation inhibitor. (2014) (14)
- Synergistic inhibition of phorbol ester-induced transformation of JB6 cells by transforming growth factor-beta and retinoic acid. (1991) (14)
- A transforming activity not detected by DNA transfer to NIH 3T3 cells is detected by JB6 mouse epidermal cells (1985) (13)
- A Dominant-Negative c-jun Mutant Inhibits Lung Carcinogenesis in Mice (2010) (13)
- cDNA cloning and mapping of mouse pleckstrin (Plek), a gene upregulated in transformation-resistant cells. (2000) (12)
- Transfer by pro gene transfection of tumor promoter-sensitive phenotype to promotion-insensitive JB6 cells. (1988) (12)
- Tumor promotion and preneoplastic progression. (1980) (12)
- Use of Mouse JB6 Cells to Identify Molecular Targets and Novel Agents for Prevention of Carcinogenesis (1997) (12)
- Possible involvement of a lanthanide-sensitive protein kinase C substrate in lanthanide promotion of neoplastic transformation. (1986) (12)
- Power frequency magnetic fields do not contribute to transformation of JB6 cells. (1997) (11)
- Phosphorylation status and function of P53 are inversely related to protein kinase C activation. (2000) (10)
- Grafting assay distinguishes promotion sensitive from promotion resistant JB6 cells. (1997) (10)
- PDCD4 regulates axonal growth by translational repression of neurite growth-related genes and is modulated during nerve injury responses (2020) (10)
- Activation of NF-κB Is Required for PDGF-B Chain to Transform NIH3T3 Cells (2002) (10)
- Do interleukin polymorphisms play a role in the prevention of colorectal adenoma recurrence by dietary flavonols? (2011) (9)
- Comparison of mouse pro-1 and pro-2 transfectants for responses to tumor promoters and antipromoters. (1988) (9)
- Molecular Targets for Cancer Prevention (2002) (9)
- A simple method using PCR for direct sequencing of genomic DNA from frozen tumor tissue embedded in optimal cutting temperature compound. (1992) (9)
- The in vivo binding of beta-propiolactone to mouse skin DNA, RNA, and protein. (1968) (9)
- Hexose uptake as an indicator of JB6 mouse epidermal cell resistance to the mitogenic activity of TPA (1983) (8)
- US National Cancer Institute-China Collaborative Studies on Chinese Medicine and Cancer. (2017) (8)
- Diaryl Disulfides as Novel Stabilizers of Tumor Suppressor Pdcd4 (2016) (7)
- The role of mitogenic stimulation and specific glycoprotein changes in the mechanism of late-stage promotion in JB-6 epidermal cell lines. (1982) (7)
- Activation of NF-kappaB is required for PDGF-B chain to transform NIH3T3 cells. (2002) (7)
- Sequence of manganese superoxide dismutase-encoding cDNAs from multiple mouse organs. (1993) (6)
- The small molecule NSC676914A is cytotoxic and differentially affects NFκB signaling in ovarian cancer cells and HEK293 cells (2014) (6)
- Drug-induced reversion of progression phenotype is accompanied by reversion of AP-1 phenotype in JB6 cells (1996) (6)
- American Cancer Society workshop on tumor promotion and antipromotion. (1987) (6)
- Nothospondin, a new AP-1 inhibitory quassinoid from the Cameroonian plant Nothospondias staudtii. (2011) (6)
- Chemical transformation of mouse epidermal cell cultures. Abstr. (1976) (5)
- Sequence and localization of a novel FK506-binding protein to mouse chromosome 11. (1993) (5)
- Status of the mdm-2 and waf-1 genes in mouse epidermal jb6 variants harboring wild-type p53 - a p53-independent induction of waf-1. (1995) (5)
- Membrane and genetic events in tumor promotion: studies with promoter resistant variants of JB6 cells. (1983) (5)
- Molecular targets for cancer prevention: a meeting review of the third American Cancer Society-Schilling Research Conference. (2002) (5)
- Differential expression of TIMP-3 during neoplastic progression in the mouse JB6 model system. (1997) (4)
- Protein-Manganese Superoxide Dismutase Translocation and Targets Mitochondrial Oxidative Defense p 53 Translocation to Mitochondria Precedes Its Nuclear (2005) (4)
- Inhibition of tumor promoter induced transformation by retinoids that transrepress AP-1 without transactivating RARE (1996) (4)
- Cryptotanshinone, a Stat3 inhibitor, suppresses colorectal cancer proliferation and growth in vitro (2015) (3)
- A legume enriched diet facilitates weight loss and improves biomarkers of insulin resistance and inflammation (2010) (3)
- Reduced trisialoganglioside synthesis in chemically but not mos-transformed mouse epidermal cells. (1984) (3)
- Studies of the reaction of beta-propiolactone with deoxyguanosine and related compounds. (1965) (3)
- Comparison of P+ ‐active and ‐inactive pro‐1 homologues from human nasopharyngeal carcinoma cells (1988) (3)
- The role of phorbol ester receptor binding in responses to promoters by mouse and human cells. (1983) (3)
- Reduced Energy Intake and Weight Loss on a Legume-Enriched Diet Lead to Improvements in Biomarkers Related to Chronic Disease (2011) (3)
- Differential induction of 15 and 16 kDa nuclear proteins in promotion sensitive and promotion resistant mouse JB6 cells. (1992) (3)
- Transfer of phorbol ester promotability by transfection of DNA from promotable into nonpromotable cells. (1983) (3)
- Lack of p 65 / Nuclear Factor-Transformation Nonresponsive Cells Owe Their Resistance to Updated (2001) (3)
- Role of specific membrane and genetic changes in the mechanism of tumour promotion. Studies with promoter-resistant variants. (1984) (3)
- Inhibition of tumor promoter induced transformation by expression of the small GTP-binding protein Rac in JB6 cells. (1997) (2)
- Pdcd4 targets eIF4A to inhibit translation, transcription, tumorigenesis, and invasion (2006) (2)
- Phorbol ester-induced anchorage independence and its antagonism by retinoic acid correlates with altered synthesis of procollagen (1981) (2)
- Abstract A27: STAT2 contributes to promotion of colorectal and skin carcinogenesis (2010) (2)
- Diallyl Disul fi de ( DADS ) , a Constituent of Garlic , Inactivates NFk B and Prevents Colitis-Induced Colorectal Cancer by Inhibiting GSK-3 b (2016) (2)
- The presence in a mouse T cell line of a 97-kDa protein kinase C (PKC) with characteristics similar to known members of the novel PKC subgroup and its possible role in lymphocyte gene expression. (1992) (2)
- Evidence that mouse promotion-sensitivity gene pro1 is transcribed by RNA polymerase III. (1988) (2)
- Cyclic AMP elevating drugs inhibit proliferation of keratinizing epidermal cells (1974) (1)
- Genes and membrane signals involved in neoplastic transformation. (1985) (1)
- A selective small molecule NF-kB inhibitor from a high-throughput cell based assay for “AP-1 hits” (2007) (1)
- Stuart H. Yuspa receives the clowes cward (1993) (1)
- Transfer ofSensitivity toTumorPromoters byTransfection of DNA fromSensitive into Insensitive MouseJB6Epidermal Cells (1983) (1)
- Abstract A65: Identification of inflammation-associated plasma markers as response indicators in human colorectal cancer patients consuming freeze-dried black raspberries (2008) (1)
- Anthocyanidins inhibit (2003) (1)
- All- trans -Retinoic acid (ATRA) and Arsenic Trioxide-Induced Expression and Regulation of Programmed Cell Death 4 (PDCD4) in Acute Promyelocytic Leukemia. (2004) (1)
- Abstract 1481: Srx-Prx IV axis is required for human lung cancer cell maintenance, migration, and invasion (2010) (1)
- MicroRNA-29 Stabilizes IFN-{gamma} mRNA by inhibiting GW182 (2012) (1)
- Title: Diallyl Disulfide (DADS), a constituent of garlic, inactivates NFκB and prevents colitis-induced colorectal cancer by inhibiting GSK-3β Running Title: Diallyl Disulfide (DADS) prevents colorectal cancer in mice (2016) (0)
- Microwave-Based Reaction Screening: Tandem Retro-Diels—Alder/Diels—Alder Cycloadditions of o-Quinol Dimers. (2012) (0)
- Working hypothesis (2020) (0)
- Abstract B59: Magnetic resonance imaging monitoring of tumor promotion and tumor progression in mouse model of inflammation-promoted colon cancer (2008) (0)
- Abstract 2578: Berberine suppress the colon cancer proliferation through activating AMPK. (2013) (0)
- Tumor-promoter-resistant cells lack trisialoganglioside response ( tumor-promotion mechanism / mouse JB 6 cell / phorbol ester / glycolipid ) (0)
- Novel tumor suppressor protein programmed cell death 4 (PDCD4) suppresses activity of PI3K/Akt pathway and regulates expression of p27 (Kip1), c-myc, DAP5 and Willm’s tumor (WT1) in acute myeloid leukemia cells (2007) (0)
- Mouse Epidermal Cells-Tetradecanoylphorbol-13-acetate-resistant and-sensitive O Phorbol Diester and Epidermal Growth Factor Receptors in 12-Updated Version (2006) (0)
- MicroRNA-29 Stabilizes IFN-γ mRNA by inhibiting GW182 (174.5) (2012) (0)
- Identification of inflammation-associated serum and colon markers as indicators of nutritional attenuation of colon carcinogenesis in AOM-induced ob/ob mice consuming dietary navy beans and their fractions (2007) (0)
- Abstract A54: Changes in fatty acid profile indicate a chemo-preventive response to navy bean extract in an inflammation-associated colorectal cancer mouse model (2016) (0)
- For Peer Review Loss of Sulfiredoxin Renders Mice Resistance to Azoxymethane/Dextran Sulfate Sodium Induced Colon Carcinogenesis (2013) (0)
- Correction: Role of 3′UTRs in the Translation of mRNAs Regulated by Oncogenic eIF4E—A Computational Inference (2009) (0)
- The Binding of ß-Propiolactoneand Some Related Alkylating Agents to DNA, RNA, and Protein of Mouse Skin; Relation between Tumor-initiating Power of Alkylating Agents and Their Binding to DNA1 (2006) (0)
- Abstract 4118: To dine with red wine: Systems approach to studying resveratrol's protection against inflammatory colorectal cancer (2014) (0)
- Abstract A112: Flavonol intake may modify the association between interleukin genetic polymorphisms and colorectal adenoma recurrence in the polyp prevention trial (2010) (0)
- Gene Regulation and Genetic Susceptibility to Neoplastic Transformation : AP-1 and p 80 Expression in JB 6 Cells by Lori (2006) (0)
- Abstract 2727: Sulfiredoxin is required for AOM/DSS induced mouse colon carcinogenesis and invasiveness of human colon cancer cells. (2013) (0)
- Abstract A15: Inflammation-dependent deregulation of the tumor suppressor Pdcd4 (2011) (0)
- Abstract B73: Increased serum fatty acyl carnitine levels may indicate development of advanced colorectal adenoma (2016) (0)
- The in Vivo Binding of ß-Propiolactone to Mouse Skin DNA, RNA, and Protein1 (2006) (0)
- TGF-β Is a Critical Target Linked to Diet and the Risk of Cancer (2009) (0)
- 216 STAT2 Contributes to inflammation-induced colorectal cancer (2008) (0)
- Expression of a dominant negative c-jun under constitutive or inducing conditions inhibits ap-1 and nfkb, and reverses tumor phenotype in transformed human keratinocvtes (1998) (0)
- PI3K/Akt/mTOR pathway constitutively suppresses expression of programmed cell death 4 (PDCD4) tumor suppressor protein in acute myeloid leukemia and breast cancer cells (2007) (0)
- The Legume Inflammation Feeding Experiment (LIFE): Effects of Gut Hormone Levels (2009) (0)
- Colorectal Cancer Is Mediated by Oncogenic Src and Chemopreventive Activity of Plant Flavonoid Isorhamnetin in (2013) (0)
- John A. Milner: In Memoriam (1947–2013) (2014) (0)
- Abstract A19: The Srx-Prx IV axis promotes human lung cancer progression through modulation of specific phosphokinase signaling (2010) (0)
- Abstract ED03-03: Dietary interventions to prevent colon cancer and discover biomarkers in mice and humans (2012) (0)
- which It Specifically Inhibits Tumorigenesis Cyclooxygenase-2 and Osteopontin under Conditions in Dominant-Negative Activator Protein 1 ( TAM 67 ) Targets (2007) (0)
- Abstract B83: Sulfiredoxin is an AP-1 target gene that is required for transformation and shows elevated expression in human skin tumors (2008) (0)
- Identification of translational targets of tumor suppressor Pdcd4 through analysis of polysomal mRNA recruitment (2007) (0)
- Association between Serum Cytokine Concentrations, Flavonol Intake and Colorectal Adenoma Recurrence in the Polyp Prevention Trial (PPT) (2010) (0)
- Inflammation-associated genes as potential molecular targets for dietary prevention of colon carcinogenesis in an AOM-DSS mouse model (2007) (0)
- Endoscopic Optical Biopsy of Experimental Colitis Associated Cancer Using a Gamma-Glutamyltransferase Activatable Fluorescence Imaging Probe (2011) (0)
- Studies on the molecular mechanism of carcinogenesis by beta-propiolactone. (1969) (0)
- Differential expression of an 80-kDa protein kinase C substrate in preneoplastic and neoplastic mouse JB 6 cells ( phosphoprotein / tumor promotion / p 8 O antibody / tumor phenotype ) (2004) (0)
- Abstract 1986: Tumor suppressor PDCD4 inhibits NFκB dependent transcription in human glioblastoma cells by direct interaction with p65. (2013) (0)
- Genetic mechanisms of tumor promotion (1984) (0)
- Linking Molecular Events to Cellular Responses at Low Dose Exposures (2000) (0)
- Abstract 3079: Identification of the translational targets of tumor suppressor Pdcd4 (2011) (0)
- Genes and Signals Involved in Tumor Promoter-Induced Transformation (2020) (0)
- Growth factors, tumor promoters and cancer genes : proceedings of a Triton Biosciences-UCLA Symposium held in Steamboat Springs, Colorado, April 6-13, 1986 (1988) (0)
- Identification of dominant negative AP-1 (TAM67) target genes important for inhibition of tumorigenesis but not cell proliferation or survival. (2006) (0)
- Abstract 957: Dietary flavonols protect against colorectal carcinogenesis in an AOM-DSS mouse model for colorectal cancer (2010) (0)
- P5. Evidence of Pdcd 4 as a novel marker for tumor diagnosis and progression in resected colorectal carcinomas (2006) (0)
- p38 MAPK Signaling Mediates Retinoic Acid-Induced Expression of a Novel Tumor Suppressor Protein Programmed Cell Death 4 (PDCD4) in Acute Promyelocytic Leukemia Cells. (2006) (0)
- The small molecule NSC676914A is cytotoxic and differentially affects NFκB signaling in ovarian cancer cells and HEK293 cells (2014) (0)
- VCP functions in aggresome formation (2006) (0)
- Abstract A76: Diet versus drug paradigm for the prevention of colorectal cancer: Isorhamnetin and resveratrol versus sulindac and DFMO (2012) (0)
- Ozone Inhalation with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone and/or Dibutyl Phthalate Induced Cell Cycle Alterations via Wild-type p53 Instability in B6C3F1 Mice (2004) (0)
- Isolation and Characterization of a Transformation-Associated Gene from Human Nasopharyngeal Carcinoma Cells (1991) (0)
- Programmed cell death 4 (pdcd4) tumor suppressor protein is constitutively repressed by PI3K/Akt/mTOR pathway, NF-kb and c-myc in acute myeloid leukemia cells (2008) (0)
- A Transforming Activity NotDetected byDNA Transfer toNIH 3T3Cells IsDetected byJB6MouseEpidermal Cells (1985) (0)
- AP-1 blockade in vivo suppresses development of mammary tumor im MMTV- erbB2 mice (2006) (0)
- TPA-inducible proteins may account for sensitivity to promotion of transformation (1986) (0)
- The Legume Inflammation Feeding Experiment (LIFE): Weight Loss Effects (2009) (0)
- Role of TNF in colon carcinogenesis (2008) (0)
- [Effect of increase of cyclic AMP on the growth of cultures of guinea pig keratinocytes of the epidermis and fibroblasts of the dermis]. (1974) (0)
- P4. Tumor suppressor Pdcd4 inhibits invasion and regulates urokinase-receptor (u-PAR) gene expression via Sp-transcription factors (2006) (0)
- Abstract 198: Resveratrol's Metabolomic biomarkers of efficacy: the missing link to chemoprevention. (2013) (0)
- Interaction domains of the tumor suppressor Pdcd4 and translation initiation factors eIF4A and eIF4G (2004) (0)
- ominant-Negative c-jun Mutant Inhibits Lung Pr R cinogenesis in Mice (2010) (0)
- A tricyclic sesquiterpene from Eriophyllum lanatum stabilizes the tumor suppressor protein Pdcd4 by Inhibiting the E3-Ligase β-TrCP1 (2012) (0)
- The Binding of ß-Propiolactone to Mouse Skin DNA in Vivo; Its Correlation with Tumor-initiating Activity1 (2006) (0)
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