Nathan J. Zvaifler

Nathan J. Zvaifler's AcademicInfluence.com Rankings

Nathan J. Zvaifler

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Philosophy

Nathan J. Zvaifler's Degrees

Doctorate Medicine University of California, San Francisco

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Nathan J. Zvaifler's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The American College of Rheumatology 1990 criteria for the classification of polyarteritis nodosa. (2010) (969)
Blood-derived nurse-like cells protect chronic lymphocytic leukemia B cells from spontaneous apoptosis through stromal cell-derived factor-1. (2000) (774)
Mesenchymal precursor cells in the blood of normal individuals (2000) (763)
How important are T cells in chronic rheumatoid synovitis? (1990) (577)
The immunopathology of joint inflammation in rheumatoid arthritis. (1973) (559)
Apoptosis in rheumatoid arthritis synovium. (1995) (400)
Plasma-cell dyscrasia with polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes: the POEMS syndrome. Distinctive radiographic abnormalities. (1980) (395)
Somatic mutations in the p53 tumor suppressor gene in rheumatoid arthritis synovium. (1997) (379)
Antiphospholipid antibodies are directed against epitopes of oxidized phospholipids. Recognition of cardiolipin by monoclonal antibodies to epitopes of oxidized low density lipoprotein. (1996) (367)
Plasma Cell Dyscrasia with Polyneuropathy, Organomegaly, Endocrinopathy, M Protein, and Skin Changes: The POEMS Syndrome REPORT ON TWO CASES AND A REVIEW OF THE LITERATURE (1980) (341)
Nurselike cells express BAFF and APRIL, which can promote survival of chronic lymphocytic leukemia cells via a paracrine pathway distinct from that of SDF-1alpha. (2005) (335)
Rheumatoid arthritis and p53: how oxidative stress might alter the course of inflammatory diseases. (2000) (279)
Distinctive features of "nurselike" cells that differentiate in the context of chronic lymphocytic leukemia. (2002) (265)
Cytokines in chronic inflammatory arthritis. I. Failure to detect T cell lymphokines (interleukin 2 and interleukin 3) and presence of macrophage colony-stimulating factor (CSF-1) and a novel mast cell growth factor in rheumatoid synovitis (1988) (254)
Cytokines in chronic inflammatory arthritis. II. Granulocyte-macrophage colony-stimulating factor in rheumatoid synovial effusions. (1989) (245)
HEMOLYTIC COMPLEMENT IN SYNOVIAL FLUID. (1964) (232)
Fibroblast-Like Synoviocytes of Mesenchymal Origin Express Functional B Cell-Activating Factor of the TNF Family in Response to Proinflammatory Cytokines1 (2005) (224)
How important are T cells in chronic rheumatoid synovitis?: II. T cell-independent mechanisms from beginning to end. (2002) (223)
Cytokines in chronic inflammatory arthritis. V. Mutual antagonism between interferon-gamma and tumor necrosis factor-alpha on HLA-DR expression, proliferation, collagenase production, and granulocyte macrophage colony-stimulating factor production by rheumatoid arthritis synoviocytes. (1990) (217)
Synovial interleukin-1 receptor antagonist and interleukin-1 balance in rheumatoid arthritis. (1994) (216)
Regional analysis of p53 mutations in rheumatoid arthritis synovium (2002) (215)
Pannus and pannocytes (1994) (205)
Cytokines in chronic inflammatory arthritis. VI. Analysis of the synovial cells involved in granulocyte-macrophage colony-stimulating factor production and gene expression in rheumatoid arthritis and its regulation by IL-1 and tumor necrosis factor-alpha. (1991) (199)
Brain-reactive lymphocytotoxic antibodies in the serum of patients with systemic lupus erythematosus. (1976) (190)
Apoptosis in rheumatoid arthritis: p53 overexpression in rheumatoid arthritis synovium. (1996) (189)
Alpha 4/beta 1 integrin (VLA-4) ligands in arthritis. Vascular cell adhesion molecule-1 expression in synovium and on fibroblast-like synoviocytes. (1992) (188)
Peripheral blood and synovial fluid monocyte activation in inflammatory arthritis. II. Low levels of synovial fluid and synovial tissue interferon suggest that gamma-interferon is not the primary macrophage activating factor. (1987) (178)
Fibroblast-like synoviocytes support B-cell pseudoemperipolesis via a stromal cell-derived factor-1- and CD106 (VCAM-1)-dependent mechanism. (2001) (176)
Cytokines in chronic inflammatory arthritis. IV. Granulocyte/macrophage colony-stimulating factor-mediated induction of class II MHC antigen on human monocytes: a possible role in rheumatoid arthritis (1989) (166)
Complement-derived leukotactic factors in inflammatory synovial fluids of humans. (1971) (166)
Regulation of joint destruction and inflammation by p53 in collagen-induced arthritis. (2002) (145)
Inflammation is preceded by tumor necrosis factor-dependent infiltration of mesenchymal cells in experimental arthritis. (2002) (144)
Regulation of synoviocyte proliferation, apoptosis, and invasion by the p53 tumor suppressor gene. (1998) (141)
Analysis of the defects responsible for the impaired regulation of Epstein-Barr virus-induced B cell proliferation by rheumatoid arthritis lymphocytes. I. Diminished gamma interferon production in response to autologous stimulation (1983) (133)
Mouth and genital ulcers with inflamed cartilage: MAGIC syndrome. Five patients with features of relapsing polychondritis and Behçet's disease. (1985) (129)
Identification of immunostimulatory dendritic cells in the synovial effusions of patients with rheumatoid arthritis. (1985) (127)
Rheumatoid knee: role of gadopentetate-enhanced MR imaging. (1990) (127)
IL-1 receptor antagonist protein production and gene expression in rheumatoid arthritis and osteoarthritis synovium. (1992) (121)
Fcγ receptor type IIIA polymorphisms influence treatment outcomes in patients with inflammatory arthritis treated with tumor necrosis factor α–blocking agents (2005) (114)
CYTOKINES IN CHRONIC INFLAMMATORY ARTHRITIS (104)
Elevated salivary and synovial fluid beta2-microglobulin in Sjogren's syndrome and rheumatoid arthritis. (1975) (104)
Rheumatoid synovitis. An extravascular immune complex disease. (1974) (103)
Pannus and pannocytes. Alternative models of joint destruction in rheumatoid arthritis. (1994) (101)
Analysis of the defects responsible for the impaired regulation of EBV-induced B cell proliferation by rheumatoid arthritis lymphocytes. II. Role of monocytes and the increased sensitivity of rheumatoid arthritis lymphocytes to prostaglandin E. (1983) (101)
Mesenchymal cells expressing bone morphogenetic protein receptors are present in the rheumatoid arthritis joint. (2000) (101)
Update in rheumatology—focus on hydroxychloroquine (1988) (100)
The pathogenesis of central nervous system manifestations of systemic lupus erythematosus. (1982) (99)
Cryoimmunoglobulinemia in rheumatoid arthritis. Significance in serum of patients with rheumatoid vasculitis. (1975) (99)
p53 overexpression in synovial tissue from patients with early and longstanding rheumatoid arthritis compared with patients with reactive arthritis and osteoarthritis. (1999) (97)
Impaired regulation of Epstein-Barr virus-induced lymphocyte proliferation in rheumatoid arthritis is due to a T cell defect. (1981) (95)
Breakdown products of C 3 in human synovial fluids. (1969) (88)
Altered regulation of Epstein-Barr virus induced lymphoblast proliferation in rheumatoid arthritis lymphoid cells. (1980) (85)
Anticytokine therapy in rheumatoid arthritis. (1997) (81)
Decreased synthesis of the third component of complement (C3) in hypocomplementemic systemic lupus erythematosus. (1972) (79)
Articular manifestations in primary hyperparathyroidism (1962) (78)
Transforming growth factor-beta 1 selectively inhibits IL-3-dependent mast cell proliferation without affecting mast cell function or differentiation. (1989) (78)
Lupus cystitis: primary bladder manifestations of systemic lupus erythematosus. (1983) (76)
Fcgamma receptor type IIIA polymorphisms influence treatment outcomes in patients with inflammatory arthritis treated with tumor necrosis factor alpha-blocking agents. (2005) (76)
Elevated autoantibody content in rheumatoid arthritis synovia with lymphoid aggregates and the effect of rituximab (2008) (72)
Epstein‐barr virus (1981) (70)
A SPECULATION ON THE PATHOGENESIS OF JOINT INFLAMMATION IN RHEUMATOID ARTHRITIS. (1965) (68)
Antigen Induced Histamine Release from Platelets of Rabbits Producing Homologous PGA Antibody. (1966) (68)
Reactions of aggregated mercaptoethanol treated gamma globulin with rheumatoid factor--precipitin and complement fixation studies. (1968) (64)
Deficient Fas ligand expression by synovial lymphocytes from patients with rheumatoid arthritis. (1997) (64)
RABBIT ANAPHYLACTIC ANTIBODY (1966) (60)
Relevance of the stroma and epithelial-mesenchymal transition (EMT) for the rheumatic diseases (2006) (60)
Pannocytes: distinctive cells found in rheumatoid arthritis articular cartilage erosions. (1997) (59)
Studies of rheumatoid synovial fluid lymphocytes. II. A comparison of their behavior with blood mononuclear cells in the autologous mixed lymphocyte reaction and response to TCGF. (1983) (57)
Down regulation of human monocyte differentiation antigens by interferon gamma. (1987) (56)
LYMPHOCYTE ALTERATION BY PROCAINAMIDE: RELATION TO DRUG-INDUCED LUPUS ERYTHEMATOSUS SYNDROME (1979) (55)
Characterization of the killer cell generated in the autologous mixed leukocyte reaction (1983) (52)
Echocardiographic assessment of cardiac structure and function in patients with rheumatoid arthritis. (1977) (49)
Peripheral blood and synovial fluid monocyte activation in inflammatory arthritis. I. A cytofluorographic study of monocyte differentiation antigens and class II antigens and their regulation by gamma-interferon. (1987) (49)
Wrist arthropathy in calcium pyrophosphate dihydrate deposition disease. (1975) (47)
Chronic Postrheumatic-Fever (Jaccoud's) Arthritis (1962) (45)
Early synovitis--synoviocytes and mononuclear cells. (1994) (45)
Synovial fluid findings in systemic lupus erythematosus (SLE) (1970) (41)
Quantitative phagocytosis by neutrophils. I. A new method with immune complexes. (1973) (40)
Rabbit homocytotropic antibody. A unique rabbit immunoglobulin analogous to human IgE. (1969) (40)
Studies of rheumatoid synovial fluid lymphocytes. I. Evidence for activated natural killer- (NK) like cells. (1982) (40)
Unusual synovial fluid findings in Reiter's syndrome. (1967) (40)
Idiopathic regional osteoporosis: a clinical spectrum. (1985) (39)
Immunologic effects of cyclophosphamide treatment in rheumatoid arthritis. (1970) (37)
Mesenchymal precursor cells (2002) (37)
Native DNA binding in rheumatoid arthritis. (1974) (35)
Pathogenesis of the joint disease of rheumatoid arthritis. (1983) (35)
Hemarthrosis associated with sodium warfarin therapy. (1976) (33)
Characterization of the natural killer-like lymphocytes in rheumatoid synovial fluid. (1985) (33)
Spondylitis in chronic ulcerative colitis. (1960) (33)
Hypocomplementemia in procainamide-associated systemic lupus erythematosus. (1976) (32)
Quantitative phagocytosis by neutrophils. II. Release of the C5-cleaving enzyme and inhibition of phagocytosis by rheumatoid factor. (1973) (32)
Cellular immunity in the joints of patients with rheumatoid arthritis and other forms of chronic synovitis. (1987) (32)
Concurrent intrathoracic Hodgkin's disease and hypertrophic osteoarthropathy. (1973) (32)
Regulation of the growth of Epstein-Barr virus-infected B cells. I. Growth regression by E rosetting cells from VCA-positive donors is a combined effect of autologous mixed leukocyte reaction and activation of T8+ memory cells. (1985) (31)
Epstein-Barr virus. Its relationship to the pathogenesis of rheumatoid arthritis. (1981) (31)
Interrelationship of rheumatoid arthritis, folic acid, and aspirin. (1971) (31)
Procainamide-lymphocyte reactions. A possible explanation for drug-induced autoimmunity. (1981) (29)
Significance of urate crystals in synovial fluids. (1963) (28)
Immunopathogenesis of rheumatoid arthritis. (1991) (28)
Axial bone density in rheumatoid arthritis: comparison of dual-energy projection radiography and dual-photon absorptiometry. (1989) (28)
Rheumatoid Arthritis: Etiology, Diagnosis, Management (1985) (27)
New perspectives on the pathogenesis of rheumatoid arthritis (1988) (27)
Calcium pyrophosphate dihydrate deposition disease without chondrocalcinosis. (1975) (27)
Immunoreactants in rheumatoid synovial effusions. (1971) (26)
Antibodies reactive with central nervous system antigens. (1983) (25)
Granulomatous angiitis of the nervous system: case report and review of the literature. (1982) (25)
Antimalarial treatment of rheumatoid arthritis. (1968) (25)
Macrophages and the synovial lining. (1995) (25)
Lymphocytotoxic antibody activity in cryoprecipitates from serum of patients with SLE. (1976) (25)
High percentage of CD8+, Leu-7+ cells in rheumatoid arthritis synovial fluid. (1992) (24)
An epidemiologic study of households exposed to canine systemic lupus erythematosus. (1980) (22)
Dendritic cell-lymphocyte clusters that form spontaneously in rheumatoid arthritis synovial effusions differ from clusters formed in human mixed leukocyte reactions. (1988) (22)
Cytology of synovial fluid in rheumatoid arthritis. (1967) (22)
Rosuvastatin: an independent analysis of risks and benefits. (2006) (22)
The removal of aggregated and nonaggregated autologous gamma globulin from rheumatoid joints. (1969) (22)
The pathogenesis of rheumatoid arthritis. A critical assessment of the role of autologous stimulation in the perpetuation of rheumatoid synovitis. (1987) (21)
Mutual antagonism between interferon-gamma and tumor necrosis factor-alpha on fibroblast-like synoviocytes: Paradoxical induction of IFN-gamma and TNF-alpha receptor expression (1993) (20)
Cryoimmunoglobulinemia in Felty's syndrome. (1976) (20)
Cytokine-induced differentiation of cultured nonadherent macrophages. (1992) (19)
Accelerated Cutaneous Nodulosis Associated with Aromatase Inhibitor Therapy in a Patient with Rheumatoid Arthritis (2009) (19)
Antibodies to nonhistone nuclear antigens and antilymphocyte antibodies among children and adults with systemic lupus erythematosus and their relatives. (1984) (19)
The association of antinuclear antibodies, antilymphocyte antibodies, and C4 activation among the relatives of children with systemic lupus erythematosus. (1982) (19)
Demonstration of a homologous anaphylactic antibody in rabbits infected with Schistosoma mansoni. (1967) (18)
Antinuclear factors and chronic articular inflammation. (1971) (18)
Generation of human cytomegalovirus-specific cytotoxic T-lymphocytes in a short-term culture. (1988) (17)
In vivo synthesis of IgG by rheumatoid synovium. (1970) (17)
RHEUMATOID FACTOR AND THE FIXATION OF COMPLEMENT * (1969) (17)
Serologic studies in a family with heterozygous C2 deficiency. (1981) (16)
Impaired killer cell generation in the autologous mixed leukocyte reaction by rheumatoid arthritis lymphocytes. (1985) (15)
Fractionated total lymphoid irradiation: a promising new treatment for rheumatoid arthritis? Yes, no, maybe. (1987) (15)
Further speculation on the pathogenesis of joint inflammation in rheumatoid arthritis. (1970) (14)
The clinical significance of deoxyribonucleic acid particles in synovial fluid. (1966) (13)
Antinuclear antibodies and nuclear antigens in rheumatoid synovial fluids. (1973) (13)
Cytokines in chronic inflammatory synovitis. (1988) (12)
Selective production of human antigen specific helper factor from normal volunteers: implications for human Ir genes. (1979) (12)
C3 metabolism in a patient with deficiency of the second component of complement (C2) and discoid lupus erythematosus. (1976) (12)
A review of the antiarthritic efficacy and safety of etodolac (1989) (11)
Lymphocyte reactivity of antisera to cryoproteins in systemic lupus erythematosus. (1979) (11)
Cytokines in chronic inflammatory arthritis. III. Rheumatoid arthritis monocytes are not unusually sensitive to γ‐interferon, but have defective γ‐interferon–mediated HLA–DQ and HLA–DR induction (1989) (11)
Differences in responses of normal and rheumatoid arthritis peripheral blood T cells to synovial fluid and peripheral blood dendritic cells in allogeneic mixed leukocyte reactions. (1989) (11)
Low prevalence of HIV-1 proviral DNA in peripheral blood monocytes and dendritic cells from HIV-1-infected individuals. (1995) (11)
Cryoglobulins in rheumatoid arthritis. (1975) (10)
Alteration of rabbit PCA reaction by drugs known to influence intracellular cyclic AMP. (1974) (10)
Gold therapy in patients with systemic lupus erythematosus. (1983) (9)
The role of T cells in rheumatoid arthritis. (1993) (9)
Rheumatoid arthritis. The multiple pathways to chronic synovitis. (1995) (9)
Vacuoles in synovial fluid leukocytes. (1966) (8)
The role of xenoantigen in the human autologous mixed lymphocyte reaction: ability to respond in the absence of exposure to xenoantigen depends on the method of T-cell preparation. (1985) (8)
Oropharyngeal Epstein-Barr virus excretion in rheumatoid arthritis. (1982) (7)
Chromic Acid Poisoning resulting from Inhalation of Mist developed from Five per cent. Chromic Acid Solution. I. Medical Aspects of Chromic Acid Poisoning. (1944) (7)
Complement-Derived Leukotactic Factors in Human Synovial Fluids (1971) (7)
Cellular Immune Events in the Joints of Patients with Rheumatoid Arthritis (1985) (7)
Antibody-mediated suppression of antibody-dependent cytotoxic effector cell function. (1979) (7)
Characterization of the precursors of the NK-like cytotoxic cells generated in the autologous mixed leukocyte reaction and by interleukin 2 activation. (1986) (7)
The Demonstration of Anaphylactic Antibody in the Primary Response of Rabbits (1967) (7)
Regulation of the growth of Epstein-Barr virus-infected B cells: temporal profile of the in vitro development of three distinct cytotoxic cells. (1986) (6)
Deforming arthritis of the hands: an unusual manifestation of polymyositis. (1981) (6)
HEMOLYTIC COMPLEMENT IN SYNOVIAL FLUID Materials and Methods (5)
Factors influencing the production of early, heat labile, rabbit anaphylactic antibody. (1969) (5)
Dendritic cells in health and disease. (1989) (5)
Nuclear antigens and antinuclear antibodies-their role in joint inflammation. (1975) (5)
Comparison of five assays for immune complexes in the rheumatic diseases. An Assessment of their validity for rheumatoid arthritis (1982) (5)
Langerhans cells in connective tissue diseases. (1987) (4)
An introduction to rheumatoid arthritis. (1989) (4)
IgE immunoglobulin in the rabbit. The histopathology of the homologous passive cutaneous anaphylaxis reaction. (1972) (4)
Characterization of a rabbit homocytotropic antibody responsible for passive cutaneous anaphylactic reactions with a short (4-hour) latent period. (1974) (3)
In vivo synthesis of immuno globulin g by the rheumatoid synovium (1969) (3)
CHAPTER 15 – Autoimmune Arthropathy: Rheumatoid Synovitis (1992) (3)
Synovial dendritic cells and T cells in rheumatoid arthritis. (1988) (3)
An office technique for identifying crystal in synovial fluid. (1975) (2)
CHAPTER 13 – HUMAN ANTIGEN SPECIFIC HELPER T CELL FACTORS IN B CELL RESPONSES (1979) (2)
Cytokines in chronic inflammatory arthritis. III. Rheumatoid arthritis monocytes are not unusually sensitive to gamma-interferon, but have defective gamma-interferon-mediated HLA-DQ and HLA-DR induction. (1989) (2)
Quantitative Phagocytosis by Neutrophils (1973) (2)
BAFF Support Survival of Chronic Lymphocytic Leukemia B Cells by a Pathway Independent of Stromal Derived Factor-1α. (2004) (1)
Nurse-like cells that support survival of chronic lymphocytic leukemia cells are derived from blood monocytes (2000) (1)
Human and mouse specific T-cell helper factors assayed in vivo and in vitro: implications for human Ir genes. (1979) (1)
From the editor: Memorable knee effusions (1982) (1)
Rheumatoid arthritis: Editorial overview (1990) (1)
Response to Proinflammatory Cytokines Cell-Activating Factor of the TNF Family in Mesenchymal Origin Express Functional B Fibroblast-Like Synoviocytes of (2004) (0)
What We Knew and What We Know : The Anticarcinogenic Action of Selenium (2004) (0)
Jarvis Edwin Seegmiller, MD, 1920–2006 (2006) (0)
1122 THE AMERICAN COLLEGE OF RHEUMATOLOGY 1990 CRITERIA FOR THE CLASSIFICATION OF GIANT CELL ARTERITIS (2010) (0)
RABBIT HOMOCYTOTROPIC ANTIBODY (1969) (0)
Nurselike Cells in Chronic Lymphocytic Leukemia (CLL) Express Both BAFF and APRIL that Protect CLL B Cells from Spontaneous Apoptosis by Paracrine Manner. (2004) (0)
Immunobiology of rheumatoid arthritis. (1976) (0)
Nurse-like cells that support leukemic B cell survival are highly effective antigen presenting cells (2000) (0)
A COMPARISON OF ANTIBODIES TO NUCLEAR AND CYTOPLASMIC ANTIGENS AMONG CHILDREN AND ADULTS WITH SLE AND THEIR FIRST DEGREE RELATIVES (1984) (0)
A retrospective analysis of the pathogenesis of rheumatoid arthritis. (1996) (0)
IMMUNOREACTANTS IN RHEUMATOID SYNOVIAL EFFUSIONS (1971) (0)
New causes of disease. (2008) (0)
Clinical Value of Systematic Examination of Synovial Fluid. (1967) (0)
184 IMPAIRED REGULATION OF EPSTEIN-BARR VIRUS OUTGROWTH (2003) (0)
Studies on hemolytic complement in synovial fluids. (1968) (0)
Simultaneous occurrence of polyarteritis nodosa and leukocytoclastic vasculitis. (1984) (0)
Nurselike Cells in Chronic Lymphocytic Leukemia Have Gene Expression Profiles and Functional Characteristics That Are Distinct from Those of Monocytes or Dendritic Cells. (2005) (0)
Possible Regulation of Autologous Mixed Lymphocyte Reaction by OKM1+ NK Cells (1988) (0)
SP0087 Tissue engineering and stem cell biology: development of bones, joints and synovium (2001) (0)
Proceedings: DNA binding in rheumatoid arthritis (RA). (1974) (0)
Joint inflammation in experimental arthritis is preceded by TNFa-dependent infiltration of the synovium by mesenchymal cells. (2001) (0)
ANTI‐LYMPHOCYTE ANTIBODIES: THEIR SIGNIFICANCE IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) (1978) (0)
Quantitative Biomarker Analysis of Anti-CCP, Rheumatoid Factor (RF) and Immunoglobulin Levels in Synovial Biopsies Indicate Enrichment and Local Production in Rheumatoid Arthritis (RA) (2007) (0)
Proceedings: DNA-binding in rheumatoid arthritis. (1974) (0)
Reactive arthritis. (1987) (0)
Rheumatology's other Nobel laureate. (2011) (0)
Grand rounds: rheumatoid arthritis. (1962) (0)

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