Norio Taira
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Norio Taira's Degrees
- PhD Pharmacology University of Tokyo
- Doctorate Medicine University of Tokyo
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(Suggest an Edit or Addition)Norio Taira's Published Works
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Published Works
- Nicorandil as a hybrid between nitrates and potassium channel activators. (1989) (317)
- Positive inotropic effect of amrinone in relation to cyclic nucleotide metabolism in the canine ventricular muscle. (1982) (193)
- Effects of new inotropic agents on cyclic nucleotide metabolism and calcium transients in canine ventricular muscle. (1986) (183)
- The autonomic pharmacology of the bladder. (1972) (135)
- PHARMACOLOGICAL PROFILE OF A NEW CORONARY VASODILATOR DRUG, 2‐NICOTINAMIDOETHYL NITRATE (SG‐75) (1979) (113)
- Similarity and Dissimilarity in the Mode and Mechanism of Action Between Nicorandil and Classical Nitrates: An Overview (1987) (112)
- Simultaneous assessment of effects of coronary vasodilators on the coronary blood flow and the myocardial contractility by using the blood-perfused canine papillary muscle. (1976) (111)
- Differences in cardiovascular profile among calcium antagonists. (1987) (103)
- Effect of reticular stimulation upon synaptic transmission in cat's lateral geniculate body. (1961) (95)
- Membrane current changes responsible for the positive inotropic effect of OPC-8212, a new positive inotropic agent, in single ventricular cells of the guinea pig heart. (1987) (91)
- Cytoplasmic calcium and the relaxation of canine coronary arterial smooth muscle produced by cromakalim, pinacidil and nicorandil (1990) (72)
- Nitroglycerin relaxes canine coronary arterial smooth muscle without reducing intracellular Ca2+ concentrations measured with fura‐2 (1989) (68)
- ASSESSMENT OF THE EFFECTS OF VASOACTIVE INTESTINAL PEPTIDE (VIP) ON BLOOD FLOW THROUGH AND SALIVATION OF THE DOG SALIVARY GLAND IN COMPARISON WITH THOSE OF SECRETIN, GLUCAGON AND ACETYLCHOLINE (1979) (65)
- Hypertensive episodes and circadian fluctuations of blood pressure in patients with phaeochromocytoma: studies by long-term blood pressure monitoring based on a volume-oscillometric method. (1988) (63)
- MECHANISMS UNDERLYING THE CARDIOVASCULAR ACTION OF A NEW DIHYDROPYRIDINE VASODILATOR, YC‐93 (1980) (62)
- Mode and mechanism of action of 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)- quinolinone (OPC-8212), a novel positive inotropic drug, on the dog heart. (1984) (61)
- Cardiohemodynamic effects of BAY a 1040 in the dog. (1972) (60)
- Coronary Vasodilator and Cardiac Effects of Optical Isomers of Verapamil in the Dog (1980) (59)
- Circumstantial evidence for increased potassium conductance of membrane of cardiac muscle by 2-nicotinamidoethyl nitrate (SG-75). (1979) (57)
- Is staurosporine a specific inhibitor of protein kinase C in intact porcine coronary arteries? (1991) (53)
- DIFFERENTIAL EFFECTS OF THE CALCIUM‐ANTAGONISTIC VASODILATORS, NIFEDIPINE AND VERAPAMIL, ON THE TRACHEAL MUSCULATURE AND VASCULATURE OF THE DOG (1980) (52)
- Modification by Islet‐Activating Protein of Direct and Indirect Inhibitory Actions of Adenosine on Rat Atrial Contraction in Relation to Cyclic Nucleotide Metabolism (1983) (51)
- Role of the Peripheral Vasculature in Changes in Venous Return Caused by Isoproterenol, Norepinephrine, and Methoxamine in Anesthetized Dogs (1978) (50)
- Separation of the Coronary Vasodilator from the Cardiac Effects of PN 200–110, a New Dihydropyridine Calcium Antagonist, in the Dog Heart (1985) (47)
- Does the positive inotropic action of a novel cardiotonic agent, MCI-154, involve mechanisms other than cyclic AMP? (1987) (47)
- PROFILE OF β‐ADRENOCEPTORS IN FEMORAL, SUPERIOR MESENTERIC AND RENAL VASCULAR BEDS OF DOGS (1977) (46)
- Spectral responses of single units in the primate visual cortex. (1962) (45)
- Differential effects of sulmazole (AR-L 115 BS) on contractile force and cyclic AMP levels in canine ventricular muscle: comparison with MDL 17,043. (1985) (44)
- Cloning and functional expression of a cardiac inward rectifier K+ channel (1994) (43)
- Comparison of the effects of the novel vasodilator FK409 with those of nitroglycerin in isolated coronary artery of the dog (1991) (42)
- The isolated and cross-circulated AV node preparation of the dog. (1972) (41)
- Vocalization response of puppies to intra-arterial administration of bradykinin and other algesic agents, and mode of actions of blocking agents. (1968) (41)
- The pharmacological behavior of the urinary bladder and its vasculature of the dog. (1968) (39)
- Is the Cardiovascular Profile of BRL 34915 Characteristic of Potassium Channel Activators? (1988) (38)
- Antiarrhythmic and bradycardic drugs inhibit currents of cloned K+ channels, KV1.2 and KV1.4. (1995) (35)
- The negative inotropic effect of nicorandil is independent of cyclic GMP changes: a comparison with pinacidil and cromakalim in canine atrial muscle (1988) (35)
- A Mammalian Transient Type K+ Channel, Rat Kv1.4, Has Two Potential Domains That Could Produce Rapid Inactivation* (1997) (34)
- Cardiovascular Profile of Ro 40–5967, a New Nondihydropyridine Calcium Antagonist, Delineated in Isolated, Blood‐Perfused Dog Hearts (1993) (34)
- Differential effects of nitroglycerin, trimetazidine, verapamil and SK&F 24260 on venous return as revealed by the open-loop method in the dog. (1980) (33)
- Details of Mode and Mechanism of Action of Denopamine, a New Orally Active Cardiotonic Agent with Affinity for β1‐Receptors (1988) (33)
- An analysis of the nitrate‐like and K channel opening actions of KRN2391 in canine coronary arterial smooth muscle (1991) (32)
- A METHOD FOR RECORDING SMOOTH MUSCLE AND VASCULAR RESPONSES OF THE BLOOD‐PERFUSED DOG TRACHEA In situ (1976) (32)
- Sensory transmission in visual pathway in various arousal states of cat. (1962) (32)
- Activation of phospholipase C by the agonist U46619 is inhibited by cromakalim-induced hyperpolarization in porcine coronary artery. (1992) (32)
- Calcitonin gene-related peptide relaxes porcine coronary arteries via cyclic AMP-dependent mechanisms, but not activation of ATP-sensitive potassium channels. (1993) (30)
- Pinacidil increases the background potassium current in single ventricular cells. (1987) (30)
- Opening of ATP-sensitive K+ channels responsible for adenosine A2 receptor-mediated vasodepression does not involve a pertussis toxin-sensitive G protein. (1993) (29)
- Excitation of autonomic nerves by 4-aminopyridine in the isolated, blood-perfused sino-atrial node preparation of the dog. (1978) (29)
- Effect of 2-nicotinamidethyl nitrate (SG-75) on membrane potentials of canine Purkinje fibers. (1981) (29)
- Mode of actions of prostaglandin F2α on the urinary bladder and its arterial bed in the dog (1974) (29)
- Effects of Neurotransmitters Injected into the Posterior and the Anterior Septal Artery on the Automaticity of the Atrioventricular Junctional Area of the Dog Heart (1975) (29)
- Relaxant mechanisms of cyclic AMP-increasing agents in porcine coronary artery. (1994) (29)
- The mode of hypotensive action of newly synthesized sydnonimine derivatives. (1971) (29)
- Interaction of potassium channel openers and blockers in canine atrial muscle (1989) (28)
- ASSESSMENT OF THE SELECTIVITY OF OPC‐2009, A NEW β2‐ADRENOCEPTOR STIMULANT, BY THE USE OF THE BLOOD‐PERFUSED TRACHEA in situ AND OF THE ISOLATED BLOOD‐PERFUSED PAPILLARY MUSCLE OF THE DOG (1977) (28)
- Increase in the slow inward current by intracellularly applied nifedipine and nicardipine in single ventricular cells of the guinea-pig heart. (1984) (28)
- Experimental Pharmacological Investigations of Effects of Nifedipine on Atrioventricular Conduction in Comparison with Those of Other Coronary Vasodilators (1975) (28)
- Dual effects of a new coronary vasodilator, diltiazem, on the contractile force of the blood-perfused papillary muscle of the dog. (1975) (27)
- VASCULAR REFLEX RESPONSES INDUCED BY AN INTRAARTERIAL INJECTION OF AZAAZEPINOPHENOTHIAZINE, ANDROMEDOTOXIN, VERATRIDINE, BRADYKININ AND KALLIKREIN AND BLOCKING ACTION OF SODIUM SALICYLATE. (1964) (27)
- Cardiohemodynamic effects of SK&F 24260, D 600, diltiazem, dilazep, and trimetazidine in the dog. (1977) (27)
- Vasodepressor mechanisms of 2-(1-octynyl)-adenosine (YT-146), a selective adenosine A2 receptor agonist, involve the opening of glibenclamide-sensitive K+ channels. (1992) (27)
- Effects on atrio-ventricular conduction of calcium-antagonistic coronary vasodilators, local anaesthetics and quinidine injected into the posterior and the anterior septal artery of the atrio-ventricular node preparation of the dog (1976) (25)
- K+ channel openers, cromakalim and Ki4032, inhibit agonist-induced Ca2+ release in canine coronary artery (1992) (25)
- The voltage‐dependent K+ channel (Kv1.5) cloned from rabbit heart and facilitation of inactivation of the delayed rectifier current by the rat β subunit (1995) (24)
- Involvement of ATP-sensitive K+ channels in the sustained coronary vasodilator response to adenosine in dogs. (1993) (23)
- Cloning and modulation by endothelin-1 of rat cardiac K channel. (1992) (23)
- Chronotropic effects of coronary vasodilators as assessed in the isolated, blood-perfused sino-atrial node preparation of the dog. (1977) (22)
- E4080 has a dual action, as a K+ channel opener and a Ca2+ channel blocker, in canine coronary artery smooth muscle. (1992) (22)
- Spasmolytic Action of Nicorandil in Canine Conductive Coronary Arteries In Vivo Is Not Modified by Glibenclamide (1992) (22)
- Histamine increases vascular tone and intracellular calcium level using both intracellular and extracellular calcium in porcine coronary arteries. (1990) (22)
- Excitation of the parasympathetic ganglia of the canine urinary bladder through a muscarinic mechanism. (1971) (21)
- Ca2+ influx induced by the agonist U46619 is inhibited by hyperpolarization induced by the K+ channel opener cromakalim in canine coronary artery. (1992) (21)
- Modification by manganese ions and verapamil of the responses of the atrioventricular node to norepinephrine. (1976) (21)
- Cardiovascular profile of Bay k 8644, a presumed calcium channel activator, in the dog (1985) (20)
- Differential coupling to positive inotropic responses of cyclic AMP produced by stimulation of beta 1- and beta 2-adrenergic receptors. (1989) (20)
- Effect of DHP‐218, a Novel Dihydropyridine Phosphonate, on Atrioventricular Nodal Conductivity Compared with Its Vascular Effect in Dogs (1987) (19)
- Sustained Coronary Constriction and Its Antagonism by Calcium‐Blocking Agents in Monkeys and Baboons (1983) (19)
- Effect of 2-nicotinamidethyl nitrate (SG-75) on the membrane potential of left atrial muscle fibres of the dog (1980) (19)
- Effects of Antiarrhythmic Drugs on AV Nodal and Intraventricular Conduction as Assessed in the Isolated, Blood‐Perfused AV Node Preparation of the Dog (1981) (19)
- Involvement of cyclic AMP in the positive inotropic effect of OPC-8212, a new cardiotonic agent, on the canine ventricular muscle. (1984) (19)
- Differential antagonism by Bay k 8644, a dihydropyridine calcium agonist, of the negative inotropic effects of nifedipine, verapamil, diltiazem and manganese ions in canine ventricular muscle (1985) (19)
- Modulation of transient type K channel cloned from rat heart. (1992) (19)
- Calcium channel-blocking drugs: a novel intervention for the treatment of cardiac disease. Introduction. (1983) (18)
- Cardiohemodynamic effects of nitroglycerin and several vasodilators. (1974) (17)
- KCl-depolarization potentiates the Ca2+ sensitization by endothelin-1 in canine coronary artery. (1992) (17)
- Specific but differential antagonism by glibenclamide of the vasodepressor effects of cromakalim and nicorandil in spinally‐anaesthetized dogs (1990) (17)
- Profile of Coronary Vasodilator and Cardiac Actions of Bepridil Revealed by Use of Isolated, Blood‐Perfused Heart Preparations of the Dog (1983) (17)
- Nicorandil increases coronary blood flow predominantly by K-channel opening mechanism (1990) (17)
- BRL 38227 (levcromakalim)-induced hyperpolarization reduces the sensitivity to Ca2+ of contractile elements in canine coronary artery (1993) (17)
- Cardiac and Coronary Vasodilator Effects of the Novel Cardiotonic Agent, MCI‐154, Assessed in Isolated, Blood‐Perfused Dog Heart Preparations (1987) (16)
- Specific antagonism by glibenclamide of negative inotropic effects of potassium channel openers in canine atrial muscle. (1990) (16)
- Differential antagonism by glibenclamide of the relaxant effects of cromakalim, pinacidil and nicorandil on canine large coronary arteries (2004) (16)
- Cloning of a swelling-induced chloride current related protein from rabbit heart. (1995) (16)
- PHARMACOLOGICAL ANALYSIS OF SALIVARY AND BLOOD FLOW RESPONSES TO HISTAMINE OF THE SUBMANDIBULAR GLAND OF THE DOG (1980) (15)
- Effects of 2-nicotinamidethyl nitrate (SG-75), a new antianginal drug, on the cyclic AMP phosphodiesterase activity. (1980) (15)
- 5-Hydroxytryptamine as a sensitizer of somatic nociceptors for pain-producing substances. (1976) (15)
- Undifferentiated effects of calcium antagonists on pressor responses to selective alpha-1 and alpha-2 adrenoceptor agonists in anesthetized, spinal dogs. (1985) (15)
- Relationship between relaxation and cyclic GMP formation caused by nicorandil in canine mesenteric artery (1983) (15)
- Cardiovascular actions of the dihydropyridine calcium antagonist nimodipine in the dog. (1984) (15)
- Inhibition of calmodulin function by CV-159, a novel dihydropyridine compound. (1988) (14)
- Differential effects of tetrodotoxin on the sialogenous and vasodilator actions of prostaglandin E2 in the dog salivary gland. (1974) (14)
- Differential sensitivity of Kv1.4, Kv1.2, and their tandem channel to acidic pH: involvement of a histidine residue in high sensitivity to acidic pH. (2001) (14)
- Prostaglandin F2α as a potent excitant of the parasympathetic postganglionic neurons of the dog salivary gland (1973) (14)
- Comparative studies on pseudaffective responses to different algesic substances in conscious dogs. The effect of sodium salicylate. (1966) (13)
- Characterization of beta-adrenoceptors in the dog saphenous vein. (1981) (13)
- Dissociation of cyclic AMP and contractile responses to isoprenaline: effects of a dihydropyridine derivative, nicardipine (YC-93), on canine ventricular muscle. (1980) (13)
- Antitachycardiac Effect of OPC‐8212, a Novel Cardiotonic Agent, on Tachycardiac Responses of Guinea Pig Isolated Right Atria to Isoproterenol and Histamine (1987) (13)
- Spectral response curves and receptive fields of pre- and postgeniculate fibres of the cat. (1960) (13)
- An analysis of direct cortical response. (1959) (12)
- Phorbol 12,13-dibutyrate increases vascular tone but has a dual action on intracellular calcium levels in porcine coronary arteries (1990) (12)
- The improvement of cardiac performance by amrinone, a new cardiotonic drug, in an experimental failing heart preparation of the dog. (1982) (12)
- Comparison of the Responses of the Simian and Canine Coronary Circulations to Autonomic Drugs (1982) (12)
- BRL 38227 (levcromakalim)-induced hyperpolarization reduces the sensitivity to Ca2+ of contractile elements in canine coronary artery (2004) (12)
- INHIBITION OF EXCITATION‐CONTRACTION COUPLING IN THE VENTRICULAR MYOCARDIUM OF THE DOG BY SKF 24260 (1976) (12)
- Pharmacological features of peripheral vascular beds of beagles. (1974) (12)
- Cardiac Versus Coronary Vasodilator Actions of KB‐944, a New Calcium Antagonist, Assessed in Isolated, Blood‐Perfused Heart Preparations of Dogs (1983) (12)
- The Mechanism Underlying the Vasodilator Action of Bunitrolol: Contribution of α1-Adrenoceptor Blocking Action (1985) (12)
- Differential modulation by beta adrenoceptors of inward calcium and delayed rectifier potassium current in single ventricular cells of guinea pig heart. (1990) (12)
- Cardiac Effects of Amiloride in the Dog (1981) (12)
- Hybrid potassium channels by tandem linkage of inactivating and non-inactivating subunits. (1994) (11)
- PORCINE CORONARY ARTERY (1992) (11)
- Differences Between Dihydropyridine and Non-Dihydropyridine Calcium Antagonists in Inotropic, Chronotropic, Dromotropic and Vascular Effects: Differences in Underlying Mechanism (1985) (11)
- Differential block by 1-hyoscyamine of the salivary and vascular responses of the dog mandibular gland to prostaglandin F2alpha. (1975) (11)
- Antihypertensive effect of nifedipine on conscious renal-hypertensive dogs. (1979) (11)
- ELECTRICAL STIMULATION OF ON- AND OFF-UNITS IN CAT'S RETINA. (1965) (11)
- Changes in the Inactivation of Rat Kv1.4 K+ Channels Induced by Varying the Number of Inactivation Particles* (2000) (11)
- Effects of amrinone on the tracheal musculature and vasculature of the dog. (1981) (11)
- Effects of nifedipine, a potent calcium-antagonistic coronary vasodilator, on atrioventricular conduction and blood flow in the isolated atrioventricular node preparation of the dog (2004) (11)
- EFFECTS OF QUINIDINE ON BLOOD FLOW RATE AND DEVELOPED TENSION IN BLOOD‐PERFUSED CANINE PAPILLARY MUSCLE (1976) (11)
- Coronary Vasodilator Compared to Cardiac Effects of PY 108–068, a New Dihydropyridine Vasodilator, on Isolated, Blood‐Perfused Dog‐Heart Preparations (1984) (11)
- Receptor-mediated modulation of rat KV1.2 in Xenopus oocytes. (1994) (11)
- PHARMACOLOGICAL ANALYSIS OF HISTAMINE RECEPTORS IN MUSCULATURE AND VASCULATURE OF THE DOG TRACHEA in situ (1978) (10)
- Selective suppression of neural excitation by tetrodotoxin injected into the canine atrioventricular node artery. (1974) (10)
- Comparison of the cardiovascular and biochemical profiles of a new positive inotropic drug, AR-L 115 BS, with those of theophylline. (1984) (10)
- A further study on antihypertensive action of beta-adrenoceptor blocking agents in conscious, renal hypertensive dogs. (1979) (10)
- Comparative study of cardiovascular profiles of milrinone and amrinone by use of isolated, blood-perfused dog heart preparations (2005) (10)
- Nicotinic acetylcholine receptors subserving nociception in the dog hindlimb. (1970) (10)
- Effects of nicorandil and its congeners on musculature and vasculature of the dog trachea in situ. (1982) (10)
- Regional difference of the direct cortical response. (1958) (9)
- Similarity and dissimilarity of the vasoconstrictor effects of Bay K 8644 on coronary, femoral, mesenteric and renal circulations of dogs (1986) (9)
- Beta 2-adrenoceptor-mediated increase in the slow inward calcium current in atrial cells. (1989) (9)
- Analyses of the cardiac action of the bradycardic agent, AQ-A 39, by use of isolated, blood-perfused dog-heart preparations. (1984) (9)
- Spectral response curves of postgeniculate neurons in the cat. (1962) (9)
- Dromotropic effects of optical isomers of beta blockers on the cross-circulated canine-atrioventricular node preparation. (1973) (9)
- Antihypertensive effect of Niludipine (Bay a 7168) on conscious renal-hypertensive dogs. (1979) (9)
- Are the cardiovascular effects of gentamicin similar to those of calcium antagonists? (1988) (9)
- Effects of semotiadil fumarate, a novel Ca2+ antagonist, on cytosolic Ca2+ level and force of contraction in porcine coronary arteries (1995) (9)
- Improvement of cardiac performance by AR-L 115 BS, a new cardiotonic drug, in the experimental failing dog heart. (1984) (8)
- Mechanism of cardiovascular action of trapidil. (1980) (8)
- Comparison of vasodilator effects of DN-9693, a selective inhibitor of cyclic AMP phosphodiesterase, and isobutylmethylxanthine, a non-selective one, in dogs. (1987) (8)
- Cardiohemodynamic effects of nipradilol (K-351) in the dog: comparison with propranolol, nadolol and prazosin. (1986) (8)
- Changes in membrane potentials and currents of ventricular cells of the guinea pig heart by a new cardiotonic drug, MCI-154. (1987) (8)
- COMPARISON OF EFFECTS OF GLUCAGON AND ISOPRENALINE ON ATRIO‐VENTRICULAR CONDUCTION AND SINO‐ATRIAL RATE IN THE DOG HEART (1974) (8)
- Inotropic Versus Chronotropic, Dromotropic, and Coronary Vasodilator Actions of DPI 201–106, a Novel Positive Inotropic Agent, in the Dog Heart (1987) (8)
- K+ channel-opening action and KRN2391-induced reduction of Ca2+ sensitivity of arterial smooth muscle. (1993) (8)
- Simultaneous assessment of the effects of trimetazidine on the myocardium and coronary vasculature of the dog. (1979) (7)
- Unitary current through the inward rectifier K+ channel cloned from rabbit heart--comparison with the native K+ channel. (1996) (7)
- A possibility that the ATP-sensitive potassium channel in coronary artery has a high-affinity internal binding site for tetraalkylammonium. (1994) (7)
- Abolition of spontaneous rhythmic contractions of isolated monkey coronary arteries by diltiazem, nifedipine, verapamil and nicorandil but not by nitroglycerin. (1985) (7)
- VASODILATATION BY PROSTAGLANDIN F2α IN THE CANINE TONGUE THROUGH A PARASYMPATHETIC MECHANISM (1978) (7)
- Coronary Vasodilator Versus Cardiac Effects of MCI‐176, a Novel Quinazolinone Calcium Antagonist, in the Dog Heart (1987) (7)
- Improvement of pentobarbital-induced heart failure by MCI-154, a novel and potent cardiotonic agent, in the dog heart-lung preparation. (1988) (7)
- Positive inotropic effect of 4-aminopyridine on dog ventricular muscle (1979) (7)
- Selectivity of alinidine, a bradycardic agent, for SA nodal automaticity versus other cardiac activities in isolated, blood-perfused dog-heart preparations. (1984) (7)
- Differential antagonism of the negative inotropic effect of gentamicin by calcium ions, Bay K 8644 and isoprenaline in canine ventricular muscle: comparison with cobalt ions (1989) (7)
- Bay K 8644, a dihydropyridine calcium agonist, augments vasoconstrictor responses to endogenous and exogenous noradrenaline in the peripheral vasculature of the dog (1985) (7)
- Differential effects of isoproterenol on the canine atrial action potential in the presence of carbachol or nicorandil. (1987) (6)
- Effect of tetrodotoxin on the bladder response to pelvic nerve stimulation and intra-arterial 1,1-dimethyl-4-phenylpiperazinium and acetylcholine in the dog. (1969) (6)
- Cardiovascular Profile of Nisoldipine as Compared to Nifedipine in Dogs (1987) (6)
- Is intra-arterial 5-hydroxytryptamine a potent algogenic substance in the dog? (1974) (6)
- Selective β1-Receptor Full Agonists, T‐0509 and T‐1583, Increase the Force Monophasically and Cyclic AMP Biphasically in Canine Ventricular Muscle (1990) (6)
- Effects on atrioventricular conduction and blood flow of enantiomers of verapamil and of tetrodotoxin injected into the posterior and the anterior septal artery of the atrioventricular node preparation of the dog (1979) (6)
- Absence of effects of class III antiarrhythmic agents on cloned cardiac K channels. (1993) (6)
- Differential effects of D 600 on release of catecholamines by acetylcholine, histamine, tyramine and by cyclic AMP from canine adrenal medulla. (1978) (6)
- Alpha-adrenergic blocking action of norephedrinetheophylline (NET) observed in the renal vascular response. (1969) (6)
- Positive dromotropic effect of dibutyryl cyclic adenosine 3',5'-monophosphate on the atrioventricular node. (1977) (6)
- An Explanation of Bell‐Shaped, Dose‐Positive Inotropic Effect Curves for Denopamine in Canine Right Ventricular Muscle (1989) (6)
- [Nifedipine: a novel vasodilator]. (2006) (6)
- Comparative study of MDL 17043 and MDL 19205, new positive inotropic agents, by use of isolated, blood-perfused dog-heart preparations (2005) (6)
- Cardiovascular actions of niludipine (BAY a 7168), a new dihydropyridine vasodilator, in the dog. (1979) (6)
- Responses of the canine saphenous vascular bed to various biogenic and foreign substances. (1970) (5)
- Improvement by trapidil of cardiac function of the dog heart-lung preparation depressed by pentobarbital. (1983) (5)
- Nicorandil as a nitrate, and cromakalim as a potassium channel opener, dilate isolated porcine large coronary arteries in an agonist-nonselective manner (1993) (5)
- Relaxation of airway smooth muscle induced by potassium in the presence of Ca-antagonists. (1989) (5)
- Cardiac versus coronary vasodilator actions of isobutylmethylxanthine in dogs: comparison with theophylline. (1986) (5)
- Effects of manganese ions and diltiazem on the spontaneous action potential of the canine atrio-ventricular node cell. (1983) (5)
- Excitation of the parasympathetic ganglia of the canine urinary bladder by a muscarinic ganglionic stimulant, 4-(m-chlorophenyl-carbamoyloxy)-2-butynyltrimethyl-ammonium chloride (McN-A-343). (1968) (5)
- Differential effects of Bay k 8644, a presumed calcium channel activator, on sinoatrial nodal and ventricular automaticity of the dog heart (1984) (5)
- The mechanism of centrally mediated cardiovascular actions of the three structurally different calcium antagonists, verapamil, diltiazem and nicardipine, in rats. (1987) (5)
- Action of oxytocin antagonists on electrical and mechanical activity of the uterus. (1967) (5)
- α-ADRENERGIC BLOCKING ACTION OF NOREPHEDRINE-THEOPHYLLINE (NET) OBSERVED IN THE RENAL VASCULAR RESPONSE (1969) (5)
- POSITIVE INOTROPIC ACTION OF GLYCERYL TRINITRATE AS OBSERVED IN THE BLOOD‐PEWUSED PAPILLARY MUSCLE PREPARATION OF THE DOG HEART (1977) (5)
- Is antagonism by Bay k 8644 of the negative dromotropic effect of nifedipine pharmacological? (1985) (5)
- Effects of calcium-antagonistic coronary vasodilators, nifedipine and verapamil, on ventricular automaticity of the dog (1978) (4)
- Potentiation of the algogenic action of bradykinin by an inhibitor of angiotensin I converting enzyme, captopril (SQ 14,225). (1979) (4)
- Effects on atrio-ventricular conduction of propranolol, pindolol and carteolol in the dog heart in situ as assessed by automated devices. (1978) (4)
- Nicorandil releases acetylcholine-induced sustained coronary arterial constriction in monkeys and baboons. (1984) (4)
- The group at C2 of N-ethylnicotinamide determines the vasodilator potencies and mechanisms of action of nicorandil and its congeners in canine coronary arteries (1991) (4)
- Amelioration of heart failure by MDL 17043 and MDL 19205, novel positive inotropic drugs, in dog heart-lung preparations. (1985) (4)
- Comparative study of coronary vasodilator and cardiac effects of nitrendipine by use of isolated, blood-perfused dog heart preparations. (1986) (4)
- Cholinergic intervention in intracardiac autonomic nerves in atrioventricular junctional area. (1980) (4)
- Modification by nicorandil and carbachol of the inward calcium current in single cells of the guinea-pig heart. (1986) (4)
- ATP-sensitive K+ channels are gradually recruited in the vasodepressor response to adenosine in spinally-anesthetized dogs. (1992) (4)
- A device for automatic plotting of the atrioventricular conduction time. (1971) (4)
- Cardiac and coronary vasodilator profile of pimobendan, a new cardiotonic drug, revealed by use of isolated, blood-perfused dog heart preparations (2005) (4)
- Improvement of cardiac performance by pimobendan, a new cardiotonic drug, in the experimental failing dog heart. (1993) (4)
- ASSESSMENT OF THE CORONARY VASODILATOR ACTION OF SK&F 24260 IN THE DOG (1978) (3)
- α-adrenoceptors mediating the positive inotropic effect of phenylephrine in the right ventricular muscle of the monkey (Macaca fuscata) (1982) (3)
- Improvement by denopamine (TA-064) of pentobarbital-induced cardiac failure in the dog heart-lung preparation (1985) (3)
- Comparison of β-adrenergic blocking activity of eight blockers in the excised and blood-perfused canine sino-atrial node preparation (1972) (3)
- Comparison of newβ-adrenergic blockers, C-3, Kö1366, Y-6124 and YB-2, with pindolol and propranolol in the blood perfused canine papillary muscle preparation (1972) (3)
- Differential effects of organic slow inward current inhibitors, verapamil and nifedipine, on rate of atrioventricular rhythm and supraventricular tachycardia in the canine isolated, blood-perfused AV node preparation (2004) (3)
- Effects of trapidil on musculature and vasculature of the dog trachea in situ. (1981) (3)
- Cardiovascular profiles of the calcium antagonists nisoldipine and nifedipine in the blood-perfused dog heart. (1986) (3)
- Behavioural and vegetative effects of dibutyryl cyclic amp on conscious dogs (1976) (3)
- Absence of blocking effect of tetrodotoxin on the action of tyramine in the saphenous vascular bed of the dog. (1969) (3)
- Voltage- and use-dependent block of the inward calcium current by MCI-176, a new non-dihydropyridine calcium antagonist, in canine ventricular muscles and single ventricular cells of the guinea-pig. (1988) (3)
- Cardiohemodynamic effects of cromakalim and pinacidil, potassium-channel openers, in the dog, special reference to venous return (1989) (3)
- Effects of semotiadil (SD-3211), a benzothiazine calcium antagonist, on blood pressure and atrioventricular conductivity in anesthetized dogs. (1992) (3)
- Cardiovascular profile of AN-132, a new diamine derivative antiarrhythmic agent, revealed in the isolated, blood-perfused dog heart. (1988) (2)
- General pharmacology of the novel angiotensin converting enzyme inhibitor alacepril. 1st communication: Effects on cardiovascular, visceral and renal functions and on blood. (1986) (2)
- REACTIVE HYPEREMIA OF HINDLIMB AFTER THE TREATMENT OF IAc, FAc AND DNP (1966) (2)
- Similarity and dissimilarity in mode and mechanism of action between YT-146, a selective adenosine receptor A2 agonist, and adenosine in isolated canine hearts. (1999) (2)
- Cardiohemodynamic effect of 5-methyl-7-diethyl-amino-s-triazolo-(1,5a)pyrimidine (trapymin). (1974) (2)
- Comparison ofβ-Adrenergic blocking activity of DCI, H56/28, ICI50172, LB46, methoxamine, MJ 1999 and propranolol in the blood perfused canine papillary muscle preparation (2005) (2)
- The Effect of Calcium-Antagonists on Atrioventricular Conduction (1980) (2)
- Potentiation of norepinephrine and adenosine in the renal circulation by 2,6-bis (diethanolamino)-4,8-dipiperidino-pyrimido (5,4-d) pyrimidine (dipyridamole) treatment (preliminary report). (1968) (2)
- Absence of a neurally-mediated process in salivation and vasodilation caused by McN-A-343 in the dog submaxillary gland. (1973) (2)
- EFFECTS OF GLYCERYL TRINITRATE AND SIN‐1A ON MUSCULATURE AND VASCULATURE OF THE DOG TRACHEA in situ (1981) (2)
- Mechanisms of beta-adrenoceptor mediated increase in delayed rectifier potassium current. (1989) (2)
- Effects of Ouabain on atrioventricular conduction: simultaneous observation in the isolated AV node preparation and the in situ heart of the dog. (1980) (2)
- Effects of a new calcium entry blocking agent, KB-944, on the membrane potential and currents of mammalian ventricular muscle cells. (1985) (2)
- Cholinergic mechanism for intestinal hypermotility caused by arterial occlusion. (1970) (2)
- Beta-adrenergic blocking effect of dichloroisoprenaline (DCI), (H 56/28, I.C.I. 50172, LB 46), methoxamine (MJ 1999) and propranolol on the sinus node activity of the dog heart (1969) (2)
- Effects of 4-Aminopyridine on Cardiac Muscle (1982) (2)
- An analysis of the nitrate-like and potassium channel opening actions of KRN2391 in canine coronary arterial smooth muscle. (1992) (1)
- 355 - MODE OF ACTIONS OF PROSTAGLANDINS E 2 , F la AND F 2a IN THE DOG SALIVARY GLAND (1977) (1)
- Coronary vasodilator and cardiac effects of NKY-722, a novel hydrophilic 1,4-dihydropyridine derivative, in the blood-perfused dog heart (2005) (1)
- Electrophysiological effects of the new antiarrhythmic drug 3-(diisopropylaminoethylamino)-2',6'-dimethylpropionanilide++ + on dog cardiac muscle. (1989) (1)
- Cardiohemodynamic effect of FK409, a novel highly potent nitrovasodilator, in anesthetized dogs. (1991) (1)
- Absence of the pain-producing activity of otherwise biologically active synthetic fragments of bradykinin. (1973) (1)
- 1413 – β1-ADRENOCEPTOR-MEDIATED VASODILATATION AND SALIVATION IN THE SUBMANDIBULAR GLAND OF THE DOG (1978) (1)
- Isolated dog hearts prepared in cold tyrode solution and reperfused with arterial blood are functionally and ultrastructurally normal. (1988) (1)
- Biphasic antagonisms by beta-blockers against positive inotropic response through beta1-adrenoceptors in isolated canine right ventricular muscles: possible involvement of two beta 1-adrenoceptor subtypes. (1996) (1)
- Comparison of Β-Adrenergic blocking activity of dichloroisoprenaline (H 56/28, I.C.I. 50172, LB46), methoxamine (MJ 1999) and propranolol in the canine femoral vascular bed (1969) (1)
- ICI 147,798 Causes Insurmountable Antagonism Against T‐0509, a Selective β1-Adrenoceptor Agonist, but Surmountable Antagonism Against Isoproterenol (1993) (1)
- Is staurosporine (ST) a specific inhibitor of protein kinase C (PKC) in intact porcine coronary arteries? (1992) (1)
- Vasodilator mechanisms of action of amrinone do not involve the opening of either ATP-sensitive or Ca(2+)-activated K+ channels. (1994) (1)
- Effects of anisotropine methylbromide (Valpin) and its mixture with sulpyrine on vocalization response and spasm of intestine induced by acetylcholine in dogs. (1972) (1)
- Release of noradrenaline proposed as a mechanism for the positive inotropic action of dipyridamole (1976) (1)
- Nicotinic property of acetylcholine receptors subserving nociception in the puppy hindlimb as revealed by the activity of cholinergic agonists administered into the femoral artery. (1968) (1)
- Differential involvement of β1- and β2-receptors in positive inotropy and cAMP levels in canine ventricular muscle (1987) (1)
- Comparison of beta-adrenergic blocking effect of DCI, methoxamine, propranolol, MJ 1999, H 56-28, LB 46 and I.C.I. 50 172 on the chronotropic response to isoprenaline. (1970) (1)
- Mode of actions of prostaglandin F2 alpha on the urinary bladder and its arterial bed in the dog. (1974) (1)
- Characterization of neuronal and vascular histamine receptors mediating the salivary and vasodilator responses to histamine of the dog submandibular gland. (1981) (1)
- Calcium antagonists — New aspects and problems unsolved (1983) (1)
- Origin of hippocampal seizure. (1961) (1)
- Determination of KA values by controlled receptor expression in Xenopus oocytes (1995) (1)
- A further study of the vasodilator and negative inotropic mechanisms of action of nicorandil and its congeners in the canine heart (1994) (1)
- The role of $beta;-receptors subtypes in cardiac contractility (1992) (0)
- Effect of ivory shell toxin on the parasympathetic ganglia of the dog urinary bladder. (1972) (0)
- Cardiac and coronary effects of the new cardiotonic drug, pimobendan (1988) (0)
- Proceedings: Contractile force, the cardiac function most susceptible to tetrodotoxin. (1974) (0)
- Differential antagonism ofthenegative inotropic effect ofgentamicin bycalcium ions, BayK 8644and isoprenaline incanine ventricular muscle: comparison withcobalt ions (1989) (0)
- Cardiac effects of a new cardiotonic drug, AR-L 115 BS. (1983) (0)
- [Influences of agents which affect ionic conductance on the tachycardiac effect of catecholamines: antitachycardiac effect]. (1986) (0)
- KCl-depolarization potentiates the Ca2+ sensitization by agonists in canine coronary artery. (1993) (0)
- Absence of relation between the vocalization response and the intestinal motility induced by intraarterial administration of aza-azepinophenothiazine (RPP-201) into the mesenteric artery of the dog. (1972) (0)
- INTRODUCTION (1983) (0)
- Specific binding sites of NKY-722, a hydrophilic 1,4-dihydropyridine derivative (DHP), in the canine microsomal fractions: comparison with PN 200-110 binding (1990) (0)
- Characterization of cardiovascular actions of CS-611, a new coronary dilator, in the dog. (1981) (0)
- Mechanisms of action of nicorandil and its derivatives differ depending upon their substitution of groups in large coronary arteries. (1991) (0)
- Inactivation mechanisms in chimera K+channels (1995) (0)
- Antispasomodic and spasmolytic effects of cromakalim (BRL 34915), nicorandil, and diltiazem (1989) (0)
- [A correlation between k-complex and auditory evoked potential (ARP) during the slow wave sleep (stage 3) in man (author's transl)]. (1980) (0)
- Cardiac versus coronary dilator effects of SD-3211, a new nondihydropyridine calcium antagonist, in isolated, blood-perfused dog hearts (1990) (0)
- [Anti-arrhythmia agents and their effects on atrioventricular conduction]. (1982) (0)
- Changes in membrane ionic currents under the adrenergic-cholinergic interaction in single cells of the guinea-pig heart (1986) (0)
- Undifferentiated potentiation by Bay k 8644 of vasoconstrictor responses to endogenous and exogenous noradrenaline in the dog saphenous arterial bed. (1985) (0)
- Aspects of Potassium Channel Modulation (1995) (0)
- Increase in the slow inward current by intracellulary applied calcium-antagonists in single ventricular cells of the guinea-pig (1984) (0)
- Modification by islet activating protein of adrenergic cholinergic interaction on the rate and force of isolated rat heart preparations (1981) (0)
- Mechanisms of receptor-mediated modulation of a cardiac K channel clone. (1993) (0)
- Potassium channel openers decrease the calcium sensitivity of contractile elements in canine coronary arterial smooth muscle (1992) (0)
- Cardiovascular pharmacology — Now and future. (1993) (0)
- Selective β1-receptor full agonist, T-1583, increases cardiac contractility with less increase in myocardial oxygen consumption than isoproterenol in heart rate-controlled isolated canine heart preparations. (1989) (0)
- Nicardipine releases sustained coronary arterial constriction induced by acetylcholine in the rhesus monkey (1985) (0)
- Effects of 4-aminopyridine (4-AP) on salivary and blood flow responses of the dog submandibular gland (1979) (0)
- Nicorandil releases coronary spasm by nitroglycerin-like action in the dog. An angiographic study (1990) (0)
- The vasodepressor mechanism of action of 2-(l-octynyl)-adenosine, a novel adenosine A2 receptor agonist, does not involve inhibitory G protein in rats (1992) (0)
- IS THE INCREASED K CONDUCTANCE IN CELL MEMBRANE RESPONSIBLE FOR THE INHIBITORY EFFECT OF ACETYLCHOLINE ON ATRIOVENTRICULAR CONDUCTION? : Antiarrhythmic Drugs : IV Auditorium : PROCEEDINGS OF THE 44th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY (1980) (0)
- Influences of verapamil and nifedipine on AV junctional rhythm (1980) (0)
- Cardiovascular effects of UL-FS 49, a novel bradycardic agent, in the isolated, blood-perfused dog heart. (1991) (0)
- Effects of a new calcium-antagonist, KB-944, on membrane electrical activities in mammalian heart cells (1984) (0)
- Further evidence for postganglionic actions of prostaglandin F2 alpha and histamine in the submandibular gland of the dog. (1982) (0)
- [Determination of blood estradiol levels using an estradiol-immunoassay-kit (CIS) - its application to menopausal patients in the outpatient clinic]. (1975) (0)
- Selective Stimulation of High-Affinity β1-Receptors: Its Implication in the Treatment of Mild Heart Failure (1991) (0)
- T-1583 and forskolin are similar in their cardiac effects and dissimilar in their vascular effects (1988) (0)
- Participation of the anterior hypothalamic dopaminergic mechanism in the baroreceptor reflex in the dog. (1983) (0)
- isoproterenol, norepinephrine, and methoxamine in anesthetized dogs Role of the peripheral vasculature in changes in venous return caused by (2011) (0)
- Negative dromotropic response to phenylephrine blocked by phenoxybenzamine. (1971) (0)
- Effects of trapidil on electrical activities of canine ventricular muscle. (1980) (0)
- Effects of selective adenosine A1 and A2 agonists on KCl- or endothelin-1 induced contractions in porcine small coronary artery. (1993) (0)
- 0314 SINGLE CHANNEL CHARACTERISTICS OF THE INWARD RECTIFIER K CHANNEL CLONED FROM VENTRICULAR CELLS (1996) (0)
- EFFECTS OF T-1583 AND ISOPROTERENOL ON MYOCARDIAL CONTRACTILITY AND OXYGEN CONSUMPTION IN ISOLATED BLOOD-PERFUSED CANINE WHOLE HEART PREPARATIONS : Cardiovascular Drugs : 53 Annual Scientific Meeting, Japanese Circulation Society (1989) (0)
- 262 – EFFECTS OF CYCLIC 3′,5′-AMP AND ITS DERIVATIVES ON SINUS RATE AND CONTRACTILE FORCE OF THE CANINE HEART (1977) (0)
- Proceedings: Potentiation by 5-hydroxytryptamine of the nociceptive response of the dog to various algogenic substances injected into the femoral artery. (1974) (0)
- Inhibitory mechanisms of action of K+ channel openers on contraction induced by an agonist in canine coronary arterial smooth muscle. (1992) (0)
- Analysis of the inotropic effect of a novel, water-soluble dihydropyridine calcium antagonist, NKY-722, in isolated canine ventricular muscle. (1989) (0)
- Abolition by nicorandil of spontaneous action potentials of the small atrio-ventricular node preparation of the dog. (1985) (0)
- [Formation of secondary focus in amygdala Kindling phenomenon of the rabbit: a study by the coherence method]. (1982) (0)
- Modulation of calcium currents by NKY-722, a novel hydrophilic dihydropyrldine calcium antagonist, in single ventricular cells of the dog (1990) (0)
- Inhibitory mechanism of action of potassium channel openers on the contracture by an agonist in coronary artery. (1991) (0)
- Does forskolin actually act on the cytoplasiic side of the cell plasma membrane (1990) (0)
- Discussion : PANEL DISCUSSION ON OPINIONS OF CARDIOTONIC DRUGS : 49th Annual Scientific Session of the Japanese Circulation Society (1986) (0)
- [Proceedings: 94. Origin of automaticity of the blood-perfused canine A-V node preparation by cross-circulation]. (1973) (0)
- Mechanisms of Action (2002) (0)
- Differential antagonism by Bay K 8644 of vasodilator effects of nifedipine, diltiazem, nicorandil and nitroglycerin in dog femoral circulation (1988) (0)
- Proceedings: Pharmacological analyses of action of DBc-AMP on the central nervous system of conscious dogs. (1974) (0)
- An overview with particular reference to agents influencing excitation-contraction coupling (1990) (0)
- Effects of methylguanidine on the electrical activity of single pacemaker fibers in the sinus node of the rabbit. (1967) (0)
- Artificial Modulation of Potassium Channels (1996) (0)
- Antagonism by the S enantiomer of the dihydropyridine derivative 202-791 of the negative inotropic effects of its R enantiomer and organic calcium antagonists (1987) (0)
- Effects on A-V conduction of tetrodotoxin selectively injected into the A-V node artery of the dog. (1972) (0)
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