Nagahiro Minato
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Computer Science
Nagahiro Minato's Degrees
- PhD Computer Science University of Tokyo
- Masters Computer Science University of Tokyo
- Bachelors Computer Science University of Tokyo
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(Suggest an Edit or Addition)Nagahiro Minato's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade (2002) (2526)
- Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. (1999) (2422)
- Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice. (2001) (1639)
- Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer (2007) (1279)
- Autoantibodies against cardiac troponin I are responsible for dilated cardiomyopathy in PD-1-deficient mice (2003) (590)
- Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex. (1999) (500)
- Aberrant PD-L1 expression through 3′-UTR disruption in multiple cancers (2016) (489)
- Immunological studies on PD-1 deficient mice: implication of PD-1 as a negative regulator for B cell responses. (1998) (479)
- Rap1 Is a Potent Activation Signal for Leukocyte Function-Associated Antigen 1 Distinct from Protein Kinase C and Phosphatidylinositol-3-OH Kinase (2000) (351)
- TCGF (IL 2)-receptor inducing factor(s). I. Regulation of IL 2 receptor on a natural killer-like cell line (YT cells). (1985) (338)
- The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors (2008) (334)
- Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: implications for degradation of oxidized proteins. (1998) (295)
- Differential expression of PD-L1 and PD-L2, ligands for an inhibitory receptor PD-1, in the cells of lymphohematopoietic tissues. (2002) (278)
- Analyses of Peripheral Blood Mononuclear Cells in Operational Tolerance After Pediatric Living Donor Liver Transplantation (2004) (270)
- SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion (2007) (265)
- Pivotal Role of CXCR3 in Melanoma Cell Metastasis to Lymph Nodes (2004) (262)
- The 4F2hc/LAT1 complex transports l-DOPA across the blood–brain barrier (2000) (245)
- The bHLH gene Hes1 is essential for expansion of early T cell precursors. (1999) (239)
- Developmentally regulated expression of the PD-1 protein on the surface of double-negative (CD4-CD8-) thymocytes. (1996) (237)
- 4F2 (CD98) Heavy Chain Is Associated Covalently with an Amino Acid Transporter and Controls Intracellular Trafficking and Membrane Topology of 4F2 Heterodimer* (1999) (231)
- Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin (2007) (216)
- Safety profile and anti-tumor effects of adoptive immunotherapy using gamma-delta T cells against advanced renal cell carcinoma: a pilot study (2007) (216)
- Hes1 Directly Controls Cell Proliferation through the Transcriptional Repression of p27Kip1 (2005) (207)
- Pyramidal neurons of upper cortical layers generated by NEX-positive progenitor cells in the subventricular zone. (2005) (198)
- Mode of regulation of natural killer cell activity by interferon (1980) (197)
- Rap1 GTPase-activating Protein SPA-1 Negatively Regulates Cell Adhesion* (1999) (183)
- Rap1 GTPase: functions, regulation, and malignancy. (2003) (181)
- Rap1 Functions as a Key Regulator of T-Cell and Antigen-Presenting Cell Interactions and Modulates T-Cell Responses (2002) (180)
- Facilitation of β Selection and Modification of Positive Selection in the Thymus of Pd-1–Deficient Mice (2000) (177)
- On the heterogeneity of murine natural killer cells (1981) (175)
- Identification of the ubiquitin–protein ligase that recognizes oxidized IRP2 (2003) (175)
- Clinical, immunological, and pathological aspects of operational tolerance after pediatric living-donor liver transplantation. (2007) (175)
- Essential Requirement of Antigen Presentation by Monocyte Lineage Cells for the Activation of Primary Human γδ T Cells by Aminobisphosphonate Antigen1 (2001) (174)
- Obesity accelerates T cell senescence in murine visceral adipose tissue. (2016) (174)
- The von Hippel-Lindau Tumor Suppressor Protein Mediates Ubiquitination of Activated Atypical Protein Kinase C* (2001) (169)
- Mechanisms of lymphocyte adhesion to human vascular endothelial cells in culture. T lymphocyte adhesion to endothelial cells through endothelial HLA-DR antigens induced by gamma interferon. (1986) (162)
- Phase I/II study of adoptive transfer of γδ T cells in combination with zoledronic acid and IL-2 to patients with advanced renal cell carcinoma (2011) (157)
- Mechanism of rejection of virus persistently infected tumor cells by athymic nude mice (1979) (152)
- Targeting of Tumor Cells for Human γδ T Cells by Nonpeptide Antigens1 (2001) (145)
- Impaired T lymphocyte trafficking in mice deficient in an actin-nucleating protein, mDia1 (2007) (139)
- Myeloproliferative stem cell disorders by deregulated Rap1 activation in SPA-1-deficient mice. (2003) (138)
- Human SPA-1 Gene Product Selectively Expressed in Lymphoid Tissues Is a Specific GTPase-activating Protein for Rap1 and Rap2 (1997) (135)
- Expression and function of PD‐1 in human γδ T cells that recognize phosphoantigens (2011) (126)
- γδ T Cells and Their Potential for Immunotherapy (2014) (122)
- Influence of anti-mouse interferon serum on the growth and metastasis of tumor cells persistently infected with virus and of human prostatic tumors in athymic nude mice. (1981) (117)
- PD-1+ memory phenotype CD4+ T cells expressing C/EBPα underlie T cell immunodepression in senescence and leukemia (2009) (116)
- IL-7 promotes thymocyte proliferation and maintains immunocompetent thymocytes bearing alpha beta or gamma delta T-cell receptors in vitro: synergism with IL-2. (1989) (110)
- Myeloid cells. (2004) (108)
- Medullary thymic epithelial stem cells maintain a functional thymus to ensure lifelong central T cell tolerance. (2014) (108)
- Aquaporin‐2 trafficking is regulated by PDZ‐domain containing protein SPA‐1 (2004) (96)
- AF-6 Controls Integrin-mediated Cell Adhesion by Regulating Rap1 Activation through the Specific Recruitment of Rap1GTP and SPA-1* (2003) (93)
- Molecular cloning of a novel mitogen-inducible nuclear protein with a Ran GTPase-activating domain that affects cell cycle progression (1995) (90)
- Requirement of Species-Specific Interactions for the Activation of Human γδ T Cells by Pamidronate1 (2003) (87)
- Anti-Programmed Cell Death 1 Antibody Reduces CD4+PD-1+ T Cells and Relieves the Lupus-Like Nephritis of NZB/W F1 Mice (2010) (86)
- Essential Contribution of Germline-Encoded Lysine Residues in Jγ1.2 Segment to the Recognition of Nonpeptide Antigens by Human γδ T Cells1 (2001) (81)
- A CD153+CD4+ T Follicular Cell Population with Cell-Senescence Features Plays a Crucial Role in Lupus Pathogenesis via Osteopontin Production (2015) (81)
- In vitro potentiation of human natural killer cell activity by a streptococcal preparation, OK-432: interferon and interleukin-2 participation in the stimulation with OK-432. (1982) (78)
- Prethymic T‐cell development defined by the expression of paired immunoglobulin‐like receptors (2005) (77)
- T/NK Bipotent Progenitors in the Thymus Retain the Potential to Generate Dendritic Cells1 (2003) (77)
- Rap1 signal controls B cell receptor repertoire and generation of self-reactive B1a cells. (2006) (76)
- CD98 induces LFA‐1‐mediated cell adhesion in lymphoid cells via activation of Rap1 (2001) (75)
- Heterogeneous fibroblasts underlie age-dependent tertiary lymphoid tissues in the kidney. (2016) (75)
- Enhanced expression of programmed death-1 (PD-1)/PD-L1 in salivary glands of patients with Sjögren's syndrome. (2005) (74)
- Essential requirement of antigen presentation by monocyte lineage cells for the activation of primary human gamma delta T cells by aminobisphosphonate antigen. (2001) (74)
- Bromodomain Protein Brd4 Binds to GTPase-Activating SPA-1, Modulating Its Activity and Subcellular Localization (2004) (74)
- T Cell Lineage Determination Precedes the Initiation of TCRβ Gene Rearrangement1 (2007) (73)
- Thymic Anlage Is Colonized by Progenitors Restricted to T, NK, and Dendritic Cell Lineages1 (2005) (72)
- Adult Thymic Medullary Epithelium Is Maintained and Regenerated by Lineage-Restricted Cells Rather Than Bipotent Progenitors. (2015) (68)
- Identification of the earliest prethymic T-cell progenitors in murine fetal blood. (2004) (68)
- Complete Remission of Lung Metastasis Following Adoptive Immunotherapy Using Activated Autologous γδ T-cells in a Patient with Renal Cell Carcinoma (2010) (68)
- The impact of senescence-associated T cells on immunosenescence and age-related disorders (2018) (66)
- Claudin-4 Deficiency Results in Urothelial Hyperplasia and Lethal Hydronephrosis (2012) (63)
- BCR/ABL and IL-3 activate Rap1 to stimulate the B-Raf/MEK/Erk and Akt signaling pathways and to regulate proliferation, apoptosis, and adhesion (2006) (59)
- Requirement of species-specific interactions for the activation of human gamma delta T cells by pamidronate. (2003) (59)
- Gene Expression Profiling of Neural Stem Cells and Identification of Regulators of Neural Differentiation During Cortical Development (2011) (55)
- Rap 1 Is a Potent Activation Signal for Leukocyte Function-Associated Antigen 1 Distinct from Protein Kinase C and Phosphatidylinositol-3OH Kinase (2000) (53)
- Involvement of CD166 in the Activation of Human γδT Cells by Tumor Cells Sensitized with Nonpeptide Antigens1 (2006) (52)
- Targeting of tumor cells for human gammadelta T cells by nonpeptide antigens. (2001) (51)
- Zoledronic acid-induced expansion of γδ T cells from early-stage breast cancer patients: effect of IL-18 on helper NK cells (2013) (51)
- Expansion of natural killer cells but not T cells in human interleukin 2/interleukin 2 receptor (Tac) transgenic mice (1989) (51)
- Recognition mechanism of non‐peptide antigens by human γδ T cells (2003) (51)
- Rap1 and SPA-1 in hematologic malignancy. (2004) (51)
- Medullary thymic epithelial stem cells: role in thymic epithelial cell maintenance and thymic involution (2016) (50)
- Complete remission of lung metastasis following adoptive immunotherapy using activated autologous gammadelta T-cells in a patient with renal cell carcinoma. (2010) (49)
- C8/119S Mutation of Major Mite Allergen Derf-2 Leads to Degenerate Secondary Structure and Molecular Polymerization and Induces Potent and Exclusive Th1 Cell Differentiation1 (2000) (49)
- Antigen-driven T cell anergy and defective memory T cell response via deregulated Rap1 activation in SPA-1-deficient mice (2003) (48)
- Physiology and pathology of T-cell aging (2020) (46)
- Stabilization of iron regulatory protein 2, IRP2, by aluminum (1999) (46)
- Anti-Tumor Activity and Immunotherapeutic Potential of a Bisphosphonate Prodrug (2017) (43)
- Studies of the function of natural killer-interferon system in patients with Sjögren syndrome. (1982) (42)
- Effects of the deregulated expression of human interleukin-2 in transgenic mice. (1989) (40)
- T cell lineage determination precedes the initiation of TCR beta gene rearrangement. (2007) (40)
- Comparison of γδ T cell responses and farnesyl diphosphate synthase inhibition in tumor cells pretreated with zoledronic acid (2013) (39)
- Spa‐1 (Sipa1) and Rap signaling in leukemia and cancer metastasis (2009) (39)
- Regulation of immune responses and hematopoiesis by the Rap1 signal. (2007) (38)
- Natural killer‐interferon system in patients with preleukaemic states (1984) (38)
- Regulation of the growth and functions of cloned murine large granular lymphocyte lines by resident macrophages (1985) (38)
- CD3+4-8- alpha beta T cell population with biased T cell receptor V gene usage. Presence in bone marrow and possible involvement of IL-3 for their extrathymic development. (1992) (37)
- Nuclear SIPA1 activates integrin β1 promoter and promotes invasion of breast cancer cells (2014) (37)
- Interleukin 7 preferentially supports the growth of γδ T cell receptor-bearing T cells from fetal thymocytes in vitro (1991) (36)
- Development of Notch-dependent T-cell leukemia by deregulated Rap1 signaling. (2008) (34)
- Physiologic Thymic Involution Underlies Age-Dependent Accumulation of Senescence-Associated CD4+ T Cells (2017) (34)
- Targeting Cancer Cells with a Bisphosphonate Prodrug (2016) (34)
- Rapid αβ TCR-mediated responses in γδ T cells transduced with cancer-specific TCR genes (2009) (34)
- Osteopontin in Spontaneous Germinal Centers Inhibits Apoptotic Cell Engulfment and Promotes Anti-Nuclear Antibody Production in Lupus-Prone Mice (2016) (33)
- Identification and gene cloning of a new phosphatidylinositol-linked antigen expressed on mature lymphocytes. Down-regulation by lymphocyte activation. (1990) (33)
- Enteroendocrine Cells Are Specifically Marked by Cell Surface Expression of Claudin-4 in Mouse Small Intestine (2014) (33)
- Isolation of ON bipolar cell genes via hrGFP-coupled cell enrichment using the mGluR6 promoter. (2009) (32)
- Tangential migration and proliferation of intermediate progenitors of GABAergic neurons in the mouse telencephalon (2011) (31)
- Notch activation in thymic epithelial cells induces development of thymic microenvironments. (2009) (31)
- Essential contribution of germline-encoded lysine residues in Jgamma1.2 segment to the recognition of nonpeptide antigens by human gammadelta T cells. (2001) (31)
- E2A and CBP/p300 Act in Synergy To Promote Chromatin Accessibility of the Immunoglobulin κ Locus (2012) (30)
- Taurodeoxycholate Increases the Number of Myeloid-Derived Suppressor Cells That Ameliorate Sepsis in Mice (2018) (30)
- Involvement of CD166 in the activation of human gamma delta T cells by tumor cells sensitized with nonpeptide antigens. (2006) (30)
- Expansion of human γδ T cells for adoptive immunotherapy using a bisphosphonate prodrug (2018) (27)
- Sipa1 deficiency-induced bone marrow niche alterations lead to the initiation of myeloproliferative neoplasm. (2018) (27)
- Isolation and expression of the full-length cDNA encoding CD59 antigen of human lymphocytes. (1990) (27)
- Analytical performance of a new automated chemiluminescent magnetic immunoassays for soluble PD-1, PD-L1, and CTLA-4 in human plasma (2019) (25)
- Role of SPA-1 in phenotypes of chronic myelogenous leukemia induced by BCR-ABL-expressing hematopoietic progenitors in a mouse model. (2006) (25)
- Rap G protein signal in normal and disordered lymphohematopoiesis. (2013) (25)
- Involvement of activation-induced cytidine deaminase in skin cancer development. (2016) (25)
- Frontline Science: IL‐18 primes murine NK cells for proliferation by promoting protein synthesis, survival, and autophagy (2018) (24)
- NK 1+ CD4- CD8- alphabeta T cells in the peritoneal cavity: specific T cell receptor-mediated cytotoxicity and selective IFN-gamma production against B cell leukemia and myeloma cells. (1996) (24)
- Hassall’s corpuscles with cellular-senescence features maintain IFNα production through neutrophils and pDC activation in the thymus (2018) (23)
- Expression and rearrangement of the alpha, beta, and gamma chain genes of the T cell receptor in cloned murine large granular lymphocyte lines. No correlation with the cytotoxic spectrum (1986) (23)
- In vivo distribution of recombinant interleukin-2-activated autologous lymphocytes administered by intra-arterial infusion in patients with renal cell carcinoma. (1987) (23)
- SPA‐1 controls the invasion and metastasis of human prostate cancer (2011) (23)
- Claudin-4 induction by E-protein activity in later stages of CD4/8 double-positive thymocytes to increase positive selection efficiency (2011) (23)
- Distribution of the 4F2 light chain, LAT1, in the mouse brain (2000) (23)
- Specific recruitment of SPA-1 to the immunological synapse: involvement of actin-bundling protein actinin. (2004) (21)
- Recognition mechanism of non-peptide antigens by human gammadelta T cells. (2003) (21)
- Mitogen-inducible SIPA1 is mapped to the conserved syntenic groups of chromosome 19 in mouse and chromosome 11q13.3 centromeric to BCL1 in human. (1997) (20)
- GABAB receptor promotes its own surface expression by recruiting a Rap1-dependent signaling cascade (2015) (20)
- INTERFERON AND NK CELLS IN RESISTANCE TO PERSISTENTLY VIRUS-INFECTED CELLS AND TUMORS (1980) (19)
- The PD-1 / PD-L 1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors (2008) (19)
- Involvement of NK1+ CD4- CD8- alphabeta T cells and endogenous IL-4 in non-MHC-restricted rejection of embryonal carcinoma in genetically resistant mice. (1997) (19)
- Generation of continuous large granular lymphocyte lines by interleukin 2 from the spleen cells of mice infected with Moloney leukemia virus. Involvement of interleukin 3 (1987) (18)
- Microbiota - an amplifier of autoimmunity. (2018) (18)
- The 4 F 2 hc / LAT 1 complex transports L-DOPA across the blood – brain barrier (2000) (18)
- Classification of human liver transplant recipients by their preoperative CD8+ T cell subpopulation and its relation to outcome (2006) (17)
- Synthesis of pyrophosphate-containing compounds that stimulate Vgamma2Vdelta2 T cells: application to cancer immunotherapy. (2007) (17)
- CD153/CD30 signaling promotes age-dependent tertiary lymphoid tissue expansion and kidney injury (2021) (17)
- A recombinant murine granulocyte/macrophage (GM) colony-stimulating factor derived from an inducer T cell line (IH5.5). Functional restriction to GM progenitor cells (1986) (17)
- Crystal structure and some properties of a major house dust mite allergen, Derf 2. (2006) (17)
- A decrease in Leu-11a negative lymphocytes in relation to natural killer cell activity in chromate workers. (1991) (16)
- Cytoprotective effect of CD59 antigen on xenotransplantation immunity. (1992) (16)
- Decreases of CD4- and CD8-positive T lymphocytes in retired chromate workers. (1995) (15)
- Impaired T-cell differentiation in the thymus at the early stages of acute pathogenic chimeric simian-human immunodeficiency virus (SHIV) infection in contrast to less pathogenic SHIV infection. (2006) (14)
- Expression of murine IL-2 receptor beta-chain on thymic and splenic lymphocyte subpopulations as revealed by the IL-2-induced proliferative response in human IL-2 receptor alpha-chain transgenic mice. (1990) (14)
- INTERFERON, NK CELLS AND PERSISTENT VIRUS INFECTION * (1980) (14)
- Virus-replicating T cells in the immune response of mice. I. Virus plaque assay of the lymphocytes reactive to sheep erythrocytes (1977) (14)
- Bone Marrow Endothelial Cells Induce Immature and Mature B Cell Egress in Response to Erythropoietin. (2017) (13)
- A New Indicator of Favorable Prognosis in Locally Advanced Renal Cell Carcinomas: γδ T-Cells in Peripheral Blood (2011) (13)
- Virus-replicating T cells in the immune response of mice. II. Characterization of T cells capable of replicating vesicular stomatitis virus (1978) (13)
- Essential role of Rap signal in pre-TCR-mediated beta-selection checkpoint in alphabeta T-cell development. (2008) (13)
- Analysis of natural killer activity and natural killer cell subsets in patients with bladder cancer (2005) (13)
- Involvement of Rap-1 activation and early termination of immune synapse in CTLA-4-mediated negative signal (2009) (13)
- Inhibition of MMP-2-Mediated Mast Cell Invasion by NF-κB Inhibitor DHMEQ in Mast Cells (2015) (13)
- The potential role of Osteopontin in the maintenance of commensal bacteria homeostasis in the intestine (2017) (13)
- Developmental regulation of the extrathymic differentiation potential of the progenitor cells for T cell lineage. (1989) (12)
- Differentiation in vitro of T3+ large granular lymphocytes with characteristic cytotoxic activity from an isolated hematopoietic progenitor colony (1988) (12)
- Complementary DNA sequence and deduced peptide sequence for CD59/MEM-43 antigen, the human homologue of murine lymphocyte antigen Ly-6C. (1989) (12)
- Selective expression of claudin-5 in thymic endothelial cells regulates the blood–thymus barrier and T-cell export (2020) (12)
- Two types of antibodies inhibiting interleukin-2 production by normal lymphocytes in patients with systemic lupus erythematosus. (1989) (11)
- A new indicator of favorable prognosis in locally advanced renal cell carcinomas: gamma delta T-cells in peripheral blood. (2011) (11)
- Virus-replicating T cells in the immune response of mice. III. Role of vesicular stomatitis virus-replicating T cells in the antibody response (1978) (11)
- Intrathymic Effect of Acute Pathogenic SHIV Infection on T‐Lineage Cells in Newborn Macaques (2005) (11)
- Diverting Glycolysis to Combat Oxidative Stress -- Innovative Medicine: Basic Research and Development (2015) (11)
- Specific and high-affinity binding of tetramerized PD-L1 extracellular domain to PD-1-expressing cells: possible application to enhance T cell function. (2007) (11)
- Natural killer cell activity in workers exposed to benzidine and beta-naphthylamine. (1990) (11)
- Mutational Analysis of Superantigen Activity Responsible for the Induction of Skin Erythema by Streptococcal Pyrogenic Exotoxin C (1998) (11)
- Adult Still's disease with Sjögren's syndrome successfully treated with intravenous pulse methylprednisolone and oral cyclophosphamide. (1993) (11)
- CXCR3high CD8+ T cells with naïve phenotype and high capacity for IFN‐γ production are generated during homeostatic T‐cell proliferation (2018) (11)
- [A case of primary Sjögren's syndrome presenting as osteomalacia secondary to renal tubular acidosis]. (1991) (11)
- Regulation of TCR Vγ2 gene rearrangement by the helix-loop-helix protein, E2A. (2011) (10)
- Analysis of mechanism for human gammadelta T cell recognition of nonpeptide antigens. (2005) (10)
- Activation of CEA‐CAM‐1‐mediated cell adhesion via CD98: involvement of PKCδ (2003) (10)
- Selective impairment of alpha-interferon-mediated natural killer augmentation in Sjögren's syndrome: differential effects of alpha-interferon, gamma-interferon, and interleukin 2 on cytolytic activity. (1987) (10)
- Trypanosoma cruzi: correlation of resistance and susceptibility in infected bred mice with the in vivo primary antibody response to sheep red blood cells. (1981) (10)
- Bone marrow pre-B expansion by SL/Kh-Bomb1 locus: not sufficient for lymphomagenesis. (2008) (10)
- Crucial role of the Rap G protein signal in Notch activation and leukemogenicity of T-cell acute lymphoblastic leukemia (2015) (10)
- Innovative Medicine (2015) (10)
- Rap signaling is crucial for the competence of IL-7 response and the development of B-lineage cells. (2009) (9)
- SIPA1 enhances SMAD2/3 expression to maintain stem cell features in breast cancer cells. (2020) (9)
- Decrease of CD4-positive T lymphocytes in workers exposed to benzidine and beta-naphthylamine. (1993) (9)
- Pulmonary hypertension in systemic lupus erythematosus: a report of an autopsied case. (1994) (8)
- Human gammadelta T cells modulate the mite allergen-specific T-helper type 2-skewed immunity. (2007) (8)
- Increased c‐Myc activity and DNA damage in hematopoietic progenitors precede myeloproliferative disease in Spa‐1‐deficiency (2011) (7)
- Modification of Gene Expression, Proliferation, and Function of OP9 Stroma Cells by Bcr-Abl-Expressing Leukemia Cells (2015) (7)
- High-molecular-weight Ly-5 isoforms expressed on T cells: activation-dependent expression. (1991) (7)
- Sipa1 deficiency unleashes a host-immune mechanism eradicating chronic myelogenous leukemia-initiating cells (2018) (7)
- VIRAL MUTATION IN PERSISTENT INFECTION (1980) (7)
- Interleukin 7 preferentially supports the growth of gamma delta T cell receptor-bearing T cells from fetal thymocytes in vitro. (1991) (6)
- Selective expression and function of granzyme D in lymphohematopoietic stromal cells. (1999) (6)
- A human PSMB11 variant affects thymoproteasome processing and CD8+ T cell production. (2017) (6)
- [A case report--pulmonary cryptococcosis associated with systemic lupus erythematosus and review of 44 cases in Japan]. (1993) (6)
- Involvement of 4F2 antigen expressed on the MHC-negative target cells in the recognition of murine CD3 + CD4 − CD8 − αβ (V α 4/V β 2) T cells (1994) (6)
- Evaluation of lymphocyte subpopulations in patients with bladder cancer: a study with monoclonal antibodies. (1987) (5)
- Effects of zoledronic acid and the association between its efficacy and γδT cells in postmenopausal women with breast cancer treated with preoperative hormonal therapy: a study protocol (2014) (5)
- Rap1 signal modulators control the maintenance of hematopoietic progenitors in bone marrow and adult long‐term hematopoiesis (2019) (5)
- Activated Atypical Protein Kinase C (2001) (4)
- Combined effects of neoadjuvant letrozole and zoledronic acid on γδT cells in postmenopausal women with early-stage breast cancer. (2018) (4)
- Human Recognition of Nonpeptide Antigens by 1.2 Segment to the g Lysine Residues in J Essential Contribution of Germline-Encoded (2001) (4)
- T Cell Senescence and Autoimmunity (2015) (4)
- Thymic Development of a Unique Bone Marrow–Resident Innate-like T Cell Subset with a Potent Innate Immune Function (2019) (4)
- A circulating subset of iNKT cells mediates antitumor and antiviral immunity (2022) (4)
- A novel nuclear localization region in SIPA1 determines protein nuclear distribution and epirubicin-sensitivity of breast cancer cells. (2021) (4)
- Augmentation of delayed-type hypersensitivity by vesicular stomatitis virus infection in mice. (1980) (4)
- A murine cell line (2E10.4.13) produces five hemopoietic stimulators, and interleukin-2 and interleukin-3. (1985) (4)
- [Giant cell arteritis and polymyalgia rheumatica presenting as subclavian artery obstruction]. (1993) (4)
- cis interaction of CD153 with TCR/CD3 is crucial for the pathogenic activation of senescence-associated T cells. (2022) (3)
- Role of virus-replicating T cells in the suppression of delayed-type hypersensitivity. (1981) (3)
- Augmentation of delayed-type hypersensitivity to serum proteins by vesicular stomatitis virus infection in mice: virus-suppressor cell interactions. (1982) (3)
- Metabolic Regulation by Nuclear Receptors -- Innovative Medicine: Basic Research and Development (2015) (2)
- [An anti-T3 autoantibody in a case of chronic thyroiditis associated with Sjögren syndrome and systemic lupus erythematosus]. (1984) (2)
- Facilitation of b Selection and Modification of Positive Selection in the Thymus of PD-1–deficient Mice (2000) (2)
- Anti–PD-1 Antibody Reduces CD4PD-1 T Cells and Relieves the Lupus-Like Nephritis of NZB/W F1 Mice (2010) (2)
- Immune dysfunctions and activation of natural killer cells in human IL-2 and IL-2/IL-2 receptor L-chain transgenic mice. (1989) (2)
- Toward a new stage of PD-1 blockade cancer immunotherapy (2020) (2)
- [A case of mixed connective tissue disease exacerbated by griseofulvin complicating aseptic meningo-encephalitis and disseminated intravascular coagulation]. (1990) (2)
- Innate CD8αα+ cells promote ILC1-like intraepithelial lymphocyte homeostasis and intestinal inflammation (2019) (2)
- ANALYSIS OF PERIPHERAL BLOOD MONONUCLEAR CELLS IN OPERATIONAL TOLERANCE AFTER PEDIATRIC LIVING DONOR LIVER TRANSPLANTATION (LDLT) (2004) (2)
- Recognition and Function of HumanγδT Cells: Application for Tumor Immunotherapy (2005) (2)
- Enumeration of antigen reactive T cells against sheep erythrocytes by the virus plaque assay. (1976) (2)
- INTERACTIONS BETWEEN INTERFERON AND CELLS OF THE IMMUNE SYSTEM (1982) (2)
- VCP, a Major ATPase in the Cells, as a Novel Drug Target for Currently Incurable Disorders -- Innovative Medicine: Basic Research and Development (2015) (2)
- The impact of senescence-associated T cells on immunosenescence and age-related disorders (2018) (2)
- [Pulmonary involvement in mixed connective tissue disease]. (1988) (2)
- TIM-3 Is a Novel Therapeutic Target for Eradicating Acute Myelogenous Leukemia Stem Cells -- Innovative Medicine: Basic Research and Development (2015) (1)
- [T cell development and selection in extrathymic environments]. (1994) (1)
- Bone Marrow Endothelial Cells Take Up Blood-Borne Immune Complexes via Fcγ Receptor IIb2 in an Erythropoietin-Dependent Manner (2020) (1)
- OR.94. Human γδ T Cells: Application to Cancer Immunotherapy (2009) (1)
- Analysis of peripheral blood mononuclear cells in operational tolerance after living F-donor liver transplantation (LDLT). (2004) (1)
- TRP Channels: Their Function and Potentiality as Drug Targets -- Innovative Medicine: Basic Research and Development (2015) (1)
- Differentiation Induces Potent and Exclusive Th 1 Cell Structure and Molecular Polymerization and Derf-2 Leads to Degenerate Secondary C 8 / 119 S Mutation of Major Mite Allergen (2000) (1)
- Crystal Structure of the PD-L1 (2008) (1)
- Synaptic and Axonal Plasticity Induction in the Human Cerebral Cortex -- Innovative Medicine: Basic Research and Development (2015) (1)
- Genetic rearrangements (VDJ/CSR/SHM) (PP-080) (2010) (1)
- Fighting Fire with Fire in Cancer -- Innovative Medicine: Basic Research and Development (2015) (1)
- [Regulatory mechanisms of lymphocyte proliferation: roles of Spa-1 gene]. (1996) (1)
- Crystal Structure of the PD-1/PD-L1 Complex (2008) (1)
- An improved clonogenic culture method for thymic epithelial cells. (2019) (1)
- Involvement of 4F2 antigen expressed on the MHC-negative target cells in the recognition of murine CD3+CD4-CD8- alpha beta (V alpha 4/V beta 2) T cells. (1994) (1)
- [Immunosenescence and diseases: follicular T cell response in germinal center]. (2012) (1)
- [T-cell senescence and autoimmune diseases]. (2015) (0)
- Proceedings of the Uehara Memorial Foundation. Innovative Medicine: Basic Research and Development. Cardiac Reprogramming for Heart Repair -- Innovative Medicine: Basic Research and Development (2015) (0)
- [Evaluation of the routes of administration of a streptococcal preparation, OK-432--with special reference to augmentation of the natural killer cell activity]. (1982) (0)
- Sipa1 deficiency unleashes a host-immune mechanism eradicating chronic myelogenous leukemia-initiating cells (2018) (0)
- SLE and other connective tissue diseases (animal models) (WS-017) Chairpersons: Takayuki Sumida, Sachiko Hirose (2010) (0)
- Proliferative responsiveness of B cells from autoimmune NZB mice to anti-immunoglobulin and interleukin-4. (1989) (0)
- Cancer treating agent (2017) (0)
- Title Crucial role of the Rap G protein signal in Notch activation and leukemogenicity of T-cell acute lymphoblastic leukemia (2017) (0)
- T Cell Senescence and Autoimmunity -- Innovative Medicine: Basic Research and Development (2015) (0)
- Clarity and Challenges in Tissue Fibrosis -- Innovative Medicine: Basic Research and Development (2015) (0)
- ERRATUM (2018) (0)
- CellsRetain the Potential to Generate Dendritic T/NK Bipotent Progenitors in the Thymus (2003) (0)
- Cover Picture: Targeting Cancer Cells with a Bisphosphonate Prodrug (ChemMedChem 24/2016) (2016) (0)
- This information is current as Production in Lupus-Prone Mice and Promotes Anti-Nuclear Antibody Centers Inhibits Apoptotic Cell Engulfment Osteopontin in Spontaneous Germinal (2016) (0)
- Natural killer cell activity inworkers exposed to benzidine andf-naphthylamine (1990) (0)
- Tumor immunity and immunosurveillance (PP-093) (2010) (0)
- IL-6: A New Era for the Treatment of Autoimmune Inflammatory Diseases -- Innovative Medicine: Basic Research and Development (2015) (0)
- Natural killer cell activity in workers exposed to benzidine and f-naphthylamine (0)
- Innate CD8αα+ cells and osteopontin promote ILC1-like intraepithelial lymphocyte homeostasis and intestinal inflammation (2019) (0)
- Tumour Activity or Liver Damage (1990) (0)
- signaling Development of Notch-dependent T-cell leukemia by deregulated Rap1 (2014) (0)
- Immunopotentiating compositions containing an anti-PD-L1 antibody (2003) (0)
- PD-1 Immune Checkpoint Inhibitors and Cancer Immunotherapy (2019) (0)
- Cell-Based Regenerative Therapy for Liver Disease -- Innovative Medicine: Basic Research and Development (2015) (0)
- recognition and its disorders (2009) (0)
- TGF-β LAP Degradation Products, a Novel Biomarker and Promising Therapeutic Target for Liver Fibrogenesis -- Innovative Medicine: Basic Research and Development (2015) (0)
- Title Osteopontin in Spontaneous Germinal Centers Inhibits Apoptotic Cell Engulfment and Promotes Anti-Nuclear Antibody Production in Lupus-Prone Mice (2018) (0)
- Rigaud and Schmincke Types of Lymphoepithelioma (2011) (0)
- Unexpected Biological Effects of the Deregulated IL-2/IL-2 Receptor System on the Lymphocyte Development (1989) (0)
- Cancer Immunotherapy by Checkpoint Blockade (2016) (0)
- Crystal structure of a major house dust mite allergen, Derf 2 (2005) (0)
- Innovative Medicine: Basic Research and Development (2015) (0)
- Excerpts from the 1st international NTNU symposium on current and future clinical biomarkers of cancer: innovation and implementation, June 16th and 17th 2016, Trondheim, Norway (2016) (0)
- [PD-1 expressing T cells in leukemia]. (2012) (0)
- HETEROGENEITY AND REGULATION OF THE NATURAL KILLER CELL SYSTEM (1982) (0)
- Propagation of a unique V delta 1-bearing gamma delta T cells clone within graft infiltrates of human liver transplantation tolerance-immumoprivileged liver specific? (2007) (0)
- Effects of zoledronic acid and the association between its efficacy and γδT cells in postmenopausal women with breast cancer treated with preoperative hormonal therapy: a study protocol (2014) (0)
- Roles of E-cadherin in Hepatocarcinogenesis -- Innovative Medicine: Basic Research and Development (2015) (0)
- P1-01-04: Immunological Effects of Bisphosphonates on gdT Cells in Breast Cancer. (2011) (0)
- PROPAGATION OF A UNIQUE V 1-BEARING T CELLS CLONE WITHIN GRAFT INFILTRATES OF HUMAN LIVER TRANSPLANTATION TOLERANCE-IMMUNOPRIVILEGED LIVER SPECIFIC ?-: 1481 (2008) (0)
- Development of a New In Vivo Optical Probe for Biological Diagnosis and Therapy -- Innovative Medicine: Basic Research and Development (2015) (0)
- Immunological abnormalities in human interleukin-2 or interleukin-2/interleukin-2 receptor L chain transgenic mice. (1988) (0)
- Immunopotentiating compositions comprising anti-PD-L1 (2003) (0)
- 004 Analysis of the site for T cell mitogenic activity in the amino-terminal region of superantigen streptococcal pyrogenic exotoxin C (1997) (0)
- Activation by zoledoronic acid and IL-18 of γδ T cells from early-stage breast cancer patients in the context of helper NK cells. (2012) (0)
- Title Anti-Tumor Activity and Immunotherapeutic Potential of aBisphosphonate Prodrug (2018) (0)
- the Lupus-Like Nephritis of NZB/W F1 Mice T Cells and Relieves + PD-1+ Reduces CD4 Anti-Programmed Cell Death 1 Antibody (2010) (0)
- The Hippo Signaling Pathway: A Candidate New Drug Target for Malignant Tumors -- Innovative Medicine: Basic Research and Development (2015) (0)
- A Case of Systemic Lupus Erythematosus with Cutaneous Leukocytoclastic Vasculitis (1984) (0)
- 962 Potentiation of immunogenicity and modulation of lymphokine profile in house dust mite (Derf2) specific T cells by genetically modified allergen (2000) (0)
- ACase of Systemic Lupus Erythemat 0 sus with Cutamous Leukocytoclastic Vasculitis (2008) (0)
- Senescence-Associated CD 4 Age-Dependent Accumulation of Physiologic Thymic Involution Underlies (2017) (0)
- Title The potential role of Osteopontin in the maintenance ofcommensal bacteria homeostasis in the intestine (2018) (0)
- [Synthesis and analysis of multi-dimentional immune organ network]. (2012) (0)
- Intragraft immunoregulation-differential mechanisms of tolerance between human liver transplantation and intestinal transplantation (2007) (0)
- Analytical performance of a new automated chemiluminescent magnetic immunoassays for soluble PD-1, PD-L1, and CTLA-4 in human plasma (2019) (0)
- [Characterization of human peripheral blood lymphocytes cultured with recombinant interleukin 2]. (1988) (0)
- Excerpts from the 1st international NTNU symposium on current and future clinical biomarkers of cancer: innovation and implementation, June 16th and 17th 2016, Trondheim, Norway (2016) (0)
- Production Crucial Role in Lupus Pathogenesis via with Cell-Senescence Features Plays a T Follicular Cell Population + CD4+ A CD153 (2015) (0)
- Linear Polyubiquitination: A Crucial Regulator of NF-κB Activation -- Innovative Medicine: Basic Research and Development (2015) (0)
- The role of autoantibodies against cardiac troponin I in autoimmune dilated cardiomyopathy (2004) (0)
- PD-1 regulates self-tolerance to prevent tissue destruction (1998) (0)
- Immunoglobulin Promote Chromatin Accessibility of the E 2 A and CBP / p 300 Act in Synergy To Murre and (2012) (0)
- Autophagic Cell Death and Cancer Chemotherapeutics -- Innovative Medicine: Basic Research and Development (2015) (0)
- NAGAHIRO MINATO AND (2003) (0)
- Depressed Natural Killer Cell Activity against Measles Persistently Infected Tumor Cells in Patients with Subacute Sclerosing Panencephalitis (1983) (0)
- Anti-Tumor Activity and Immunotherapeutic Potential of a Bisphosphonate Prodrug (2017) (0)
- LineagesRestricted to T, NK, and Dendritic Cell Thymic Anlage Is Colonized by Progenitors (2005) (0)
- Rap Signaling in Normal Lymphocyte Development and Leukemia Genesis (2009) (0)
- [Interleukin 1 in host anti-tumor mechanisms]. (1987) (0)
- OJ-507 Autoantibodies against Cardiac Troponin I are the Critical Role for Autoimmune Dilated Cardiomyopathy(Cardiomyopathy, Basic (M) : OJ62)(Oral Presentation (Japanese)) (2004) (0)
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