Nahum Sonenberg

Q: What Schools Are Affiliated With Nahum Sonenberg

Nahum Sonenberg is affiliated with the following schools: McGill University, Weizmann Institute of Science, Rutgers University, University of Oxford, University of Minnesota, Victoria University of Wellington, University of Eastern Piedmont, Tel Aviv University, University of Toronto, University of Bern

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Nahum Sonenberg

Biology

#547

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#964

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Microbiology

#23

World Rank

#36

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Biology

Why Is Nahum Sonenberg Influential?

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According to Wikipedia, Nahum Sonenberg, is an Israeli Canadian microbiologist and biochemist. He is a James McGill professor of biochemistry at McGill University in Montreal, Quebec, Canada. He was an HHMI international research scholar from 1997 to 2011 and is now a senior international research scholar. He is best known for his seminal contributions to our understanding of translation, and notable for the discovery of the mRNA 5' cap-binding protein, eIF4E, the rate-limiting component of the eukaryotic translation apparatus.

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Nahum Sonenberg's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? (2008) (5037)
Upstream and downstream of mTOR. (2004) (4165)
Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets (2009) (2923)
Regulation of mRNA translation and stability by microRNAs. (2010) (2757)
eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation. (1999) (2198)
Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA (1988) (1851)
Regulation of translation initiation by FRAP/mTOR. (2001) (1574)
Translational control in stress and apoptosis (2005) (1350)
Translational control of gene expression (2000) (1317)
Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function (1994) (1312)
Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism. (1999) (1253)
Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells. (2006) (1058)
Regulation of cap-dependent translation by eIF4E inhibitory proteins (2005) (986)
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation. (2004) (962)
Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap (1990) (941)
4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway. (1998) (909)
Hierarchical phosphorylation of the translation inhibitor 4E-BP1. (2001) (886)
Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells. (2007) (876)
Translational Control of Long-Lasting Synaptic Plasticity and Memory (2009) (831)
The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC (2012) (817)
Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus (2000) (812)
The mRNA 5' cap-binding protein eIF4E and control of cell growth. (1998) (763)
Rapamycin blocks the phosphorylation of 4E‐BP1 and inhibits cap‐dependent initiation of translation. (1996) (723)
RAS/ERK Signaling Promotes Site-specific Ribosomal Protein S6 Phosphorylation via RSK and Stimulates Cap-dependent Translation* (2007) (721)
PHAS-I as a link between mitogen-activated protein kinase and translation initiation. (1994) (708)
A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampus (2001) (707)
The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the translational repressors 4E-binding proteins (1995) (696)
Translational control by 5′-untranslated regions of eukaryotic mRNAs (2016) (694)
mTORC1-Mediated Cell Proliferation, But Not Cell Growth, Controlled by the 4E-BPs (2010) (678)
Cocrystal Structure of the Messenger RNA 5′ Cap-Binding Protein (eIF4E) Bound to 7-methyl-GDP (1997) (673)
Fragile X syndrome (2017) (670)
Human eukaryotic translation initiation factor 4G (eIF4G) recruits Mnk1 to phosphorylate eIF4E (1999) (652)
The target of rapamycin (TOR) proteins (2001) (638)
Repression of cap‐dependent translation by 4E‐binding protein 1: competition with p220 for binding to eukaryotic initiation factor‐4E. (1995) (629)
Translational Repression Mediates Activation of Nuclear Factor Kappa B by Phosphorylated Translation Initiation Factor 2 (2004) (619)
Mutational analysis of a DEAD box RNA helicase: the mammalian translation initiation factor eIF‐4A. (1992) (617)
mTOR, translation initiation and cancer (2006) (612)
Bidirectional RNA helicase activity of eucaryotic translation initiation factors 4A and 4F (1990) (610)
mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation. (2013) (606)
MicroRNA Inhibition of Translation Initiation in Vitro by Targeting the Cap-Binding Complex eIF4F (2007) (604)
Targeting the translation machinery in cancer (2015) (595)
A newly identified N‐terminal amino acid sequence of human eIF4G binds poly(A)‐binding protein and functions in poly(A)‐dependent translation (1998) (593)
Inhibition of HeLa cell protein synthesis following poliovirus infection correlates with the proteolysis of a 220,000-dalton polypeptide associated with eucaryotic initiation factor 3 and a cap binding protein complex. (1982) (551)
Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase. (1992) (543)
The Fragile X Syndrome Protein Represses Activity-Dependent Translation through CYFIP1, a New 4E-BP (2008) (541)
Structural basis for 5′-nucleotide base-specific recognition of guide RNA by human AGO2 (2010) (536)
Insertion mutagenesis to increase secondary structure within the 5′ noncoding region of a eukaryotic mRNA reduces translational efficiency (1985) (532)
Akt Activates the Mammalian Target of Rapamycin by Regulating Cellular ATP Level and AMPK Activity* (2005) (530)
Regulation of Protein Synthesis by Hypoxia via Activation of the Endoplasmic Reticulum Kinase PERK and Phosphorylation of the Translation Initiation Factor eIF2α (2002) (530)
The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity (2006) (526)
La autoantigen enhances and corrects aberrant translation of poliovirus RNA in reticulocyte lysate (1993) (502)
Recognition of Polyadenylate RNA by the Poly(A)-Binding Protein (1999) (497)
Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G. (1999) (496)
Mammalian poly(A)-binding protein is a eukaryotic translation initiation factor, which acts via multiple mechanisms. (2005) (485)
Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases (2004) (479)
Pharmacological brake-release of mRNA translation enhances cognitive memory (2013) (479)
Translational control in biology and medicine (2007) (475)
The Transformation Suppressor Pdcd4 Is a Novel Eukaryotic Translation Initiation Factor 4A Binding Protein That Inhibits Translation (2003) (467)
Double-Stranded RNA-Dependent Protein Kinase Links Pathogen Sensing with Stress and Metabolic Homeostasis (2010) (465)
eIF4E – from translation to transformation (2004) (462)
eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression (2010) (459)
Autism-related deficits via dysregulated eIF4E-dependent translational control (2012) (459)
Dissecting the role of mTOR: lessons from mTOR inhibitors. (2010) (440)
The requirement for eukaryotic initiation factor 4A (elF4A) in translation is in direct proportion to the degree of mRNA 5' secondary structure. (2001) (440)
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation. (2009) (431)
Tumstatin, an Endothelial Cell-Specific Inhibitor of Protein Synthesis (2002) (425)
mRNAs containing extensive secondary structure in their 5′ non‐coding region translate efficiently in cells overexpressing initiation factor eIF‐4E. (1992) (425)
Folding of an intrinsically disordered protein by phosphorylation as a regulatory switch (2014) (423)
Interaction of polyadenylate-binding protein with the eIF4G homologue PAIP enhances translation (1998) (410)
Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E. (1996) (409)
eIF2α Phosphorylation Bidirectionally Regulates the Switch from Short- to Long-Term Synaptic Plasticity and Memory (2007) (406)
Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1 (2001) (401)
Dominant negative mutants of mammalian translation initiation factor eIF‐4A define a critical role for eIF‐4F in cap‐dependent and cap‐independent initiation of translation. (1994) (400)
Atrophy of S6K1−/− skeletal muscle cells reveals distinct mTOR effectors for cell cycle and size control (2005) (393)
Structure of translation factor elF4E bound to m7GDP and interaction with 4E-binding protein (1997) (378)
Translational control of hippocampal synaptic plasticity and memory by the eIF2α kinase GCN2 (2005) (370)
Proteolysis of human eukaryotic translation initiation factor eIF4GII, but not eIF4GI, coincides with the shutoff of host protein synthesis after poliovirus infection. (1998) (366)
A bulge structure in HIV-1 TAR RNA is required for Tat binding and Tat-mediated trans-activation. (1990) (355)
Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control (2006) (351)
Activation of translation complex eIF4F is essential for the genesis and maintenance of the malignant phenotype in human mammary epithelial cells. (2004) (346)
Cap and cap‐binding proteins in the control of gene expression (2011) (343)
Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2. (2007) (340)
Biophysical studies of eIF4E cap-binding protein: recognition of mRNA 5' cap structure and synthetic fragments of eIF4G and 4E-BP1 proteins. (2002) (339)
Eukaryotic translation initiation factors and regulators. (2003) (333)
miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4–NOT (2011) (332)
A Novel Functional Human Eukaryotic Translation Initiation Factor 4G (1998) (331)
Human eukaryotic translation initiation factor 4G (eIF4G) possesses two separate and independent binding sites for eIF4A (1997) (316)
Principles of translational control: an overview. (2012) (315)
Translational control of the innate immune response through IRF-7 (2008) (314)
A polypeptide in eukaryotic initiation factors that crosslinks specifically to the 5'-terminal cap in mRNA. (1978) (313)
4E-BP3, a New Member of the Eukaryotic Initiation Factor 4E-binding Protein Family* (1998) (312)
A Mechanism for Translationally Coupled mRNA Turnover Interaction between the Poly(A) Tail and a c-fos RNA Coding Determinant via a Protein Complex (2000) (306)
mRNA helicases: the tacticians of translational control (2011) (302)
Serum‐stimulated, rapamycin‐sensitive phosphorylation sites in the eukaryotic translation initiation factor 4GI (2000) (298)
Cap-independent translation of poliovirus mRNA is conferred by sequence elements within the 5' noncoding region (1988) (294)
The Effects of Adiponectin and Metformin on Prostate and Colon Neoplasia Involve Activation of AMP-Activated Protein Kinase (2008) (294)
Elevated levels of cyclin D1 protein in response to increased expression of eukaryotic initiation factor 4E (1993) (294)
Abrogation of translation initiation factor eIF‐2 phosphorylation causes malignant transformation of NIH 3T3 cells. (1995) (293)
MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice. (2010) (293)
The HRIGRXXR region of the DEAD box RNA helicase eukaryotic translation initiation factor 4A is required for RNA binding and ATP hydrolysis (1993) (292)
Translation initiator EIF4G1 mutations in familial Parkinson disease. (2011) (290)
The Translation Repressor 4E-BP2 Is Critical for eIF4F Complex Formation, Synaptic Plasticity, and Memory in the Hippocampus (2005) (288)
Insulin signalling and insulin actions in the muscles and livers of insulin-resistant, insulin receptor substrate 1-deficient mice (1996) (286)
mTOR signaling to translation. (2004) (285)
RNA-protein interactions in regulation of picornavirus RNA translation. (1996) (284)
A cell cycle-dependent internal ribosome entry site. (2000) (283)
Activation of GCN2 in UV-Irradiated Cells Inhibits Translation (2002) (281)
Eukaryotic Translation Initiation Factor 4E Regulates Expression of Cyclin D1 at Transcriptional and Post-transcriptional Levels (*) (1995) (278)
eIF4AIII binds spliced mRNA in the exon junction complex and is essential for nonsense-mediated decay (2004) (275)
A New Paradigm for Translational Control: Inhibition via 5′-3′ mRNA Tethering by Bicoid and the eIF4E Cognate 4EHP (2005) (266)
Targeting the eIF4F translation initiation complex: a critical nexus for cancer development. (2015) (265)
The major mRNA‐associated protein YB‐1 is a potent 5′ cap‐dependent mRNA stabilizer (2001) (264)
A cellular protein that binds to the 5'-noncoding region of poliovirus RNA: implications for internal translation initiation. (1989) (263)
Akt-Mediated YB-1 Phosphorylation Activates Translation of Silent mRNA Species (2006) (259)
mTORC1 mediated translational elongation limits intestinal tumour initiation and growth (2014) (258)
Remote Control of Gene Function by Local Translation (2014) (257)
Internal ribosome initiation of translation and the control of cell death. (2000) (256)
NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer (2016) (256)
eIF4G Dramatically Enhances the Binding of eIF4E to the mRNA 5′-Cap Structure* (1997) (255)
Regulation of Eukaryotic Initiation Factor 4E by Converging Signaling Pathways during Metabotropic Glutamate Receptor-Dependent Long-Term Depression (2006) (251)
The insulin-induced signalling pathway leading to S6 and initiation factor 4E binding protein 1 phosphorylation bifurcates at a rapamycin-sensitive point immediately upstream of p70s6k (1997) (247)
4E-BP1 phosphorylation is mediated by the FRAP-p70s6k pathway and is independent of mitogen-activated protein kinase. (1996) (246)
Activation of the translational suppressor 4E-BP1 following infection with encephalomyocarditis virus and poliovirus. (1996) (245)
Characterization of Transgenic Mice with Targeted Disruption of the Catalytic Domain of the Double-stranded RNA-dependent Protein Kinase, PKR* (1999) (243)
A role for the eIF4E-binding protein 4E-T in P-body formation and mRNA decay (2005) (239)
The eIF4E-binding proteins 1 and 2 are negative regulators of cell growth. (1996) (238)
Suppression of cap-dependent translation in mitosis. (2001) (236)
A Novel Role of the Mammalian GSPT/eRF3 Associating with Poly(A)-binding Protein in Cap/Poly(A)-dependent Translation* (2002) (235)
Epigenetic Activation of a Subset of mRNAs by eIF4E Explains Its Effects on Cell Proliferation (2007) (232)
Cap-binding proteins of eukaryotic messenger RNA: functions in initiation and control of translation. (1988) (229)
Translational repression by a novel partner of human poly(A) binding protein, Paip2. (2001) (227)
Topology and Regulation of the Human eIF4A/4G/4H Helicase Complex in Translation Initiation (2009) (226)
Eukaryotic mRNA cap binding protein: purification by affinity chromatography on sepharose-coupled m7GDP. (1979) (226)
New modes of translational control in development, behavior, and disease. (2007) (225)
Dendritic BC1 RNA: Functional Role in Regulation of Translation Initiation (2002) (224)
The dynamics of mammalian P body transport, assembly, and disassembly in vivo. (2008) (223)
Eukaryotic Translation Initiation Factor 4E (eIF4E) Binding Site and the Middle One-Third of eIF4GI Constitute the Core Domain for Cap-Dependent Translation, and the C-Terminal One-Third Functions as a Modulatory Region (2000) (223)
A conserved HEAT domain within eIF4G directs assembly of the translation initiation machinery. (2001) (222)
Structural basis for the recruitment of the human CCR4–NOT deadenylase complex by Tristetraprolin (2013) (221)
The translational inhibitor 4E-BP is an effector of PI(3)K/Akt signalling and cell growth in Drosophila (2001) (220)
Phosphorylation of eIF4E promotes EMT and metastasis via translational control of SNAIL and MMP-3 (2014) (218)
The Murine Double-Stranded RNA-Dependent Protein Kinase PKR Is Required for Resistance to Vesicular Stomatitis Virus (2000) (211)
A new translational regulator with homology to eukaryotic translation initiation factor 4G (1997) (208)
mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1. (2017) (207)
Stimulation of mammalian translation initiation factor eIF4A activity by a small molecule inhibitor of eukaryotic translation. (2005) (205)
Hepatitis C therapeutics: current status and emerging strategies (2002) (203)
A novel shuttling protein, 4E‐T, mediates the nuclear import of the mRNA 5′ cap‐binding protein, eIF4E (2000) (203)
μ-Opioid Receptor Activates Signaling Pathways Implicated in Cell Survival and Translational Control* (1998) (201)
The Leader of Human Immunodeficiency Virus Type 1 Genomic RNA Harbors an Internal Ribosome Entry Segment That Is Active during the G2/M Phase of the Cell Cycle (2003) (201)
A Novel Function of the MA-3 Domains in Transformation and Translation Suppressor Pdcd4 Is Essential for Its Binding to Eukaryotic Translation Initiation Factor 4A (2004) (199)
The mRNA closed-loop model: the function of PABP and PABP-interacting proteins in mRNA translation. (2001) (198)
miRNA-132 orchestrates chromatin remodeling and translational control of the circadian clock. (2011) (198)
14-3-3σ controls mitotic translation to facilitate cytokinesis (2007) (198)
eIF4E, the mRNA cap-binding protein: from basic discovery to translational research. (2008) (197)
Involvement of the 24-kDa cap-binding protein in regulation of protein synthesis in mitosis. (1987) (195)
Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain (2011) (194)
A Novel, Evolutionarily Conserved Protein Phosphatase Complex Involved in Cisplatin Sensitivity*S (2005) (193)
The Akt of translational control (2005) (192)
A fraction of the mRNA 5' cap-binding protein, eukaryotic initiation factor 4E, localizes to the nucleus. (1992) (192)
Antiviral effect of the mammalian translation initiation factor 2α kinase GCN2 against RNA viruses (2006) (189)
S6K1 plays a critical role in early adipocyte differentiation. (2010) (189)
Phosphoregulated FMRP phase separation models activity-dependent translation through bidirectional control of mRNA granule formation (2019) (188)
A nuclear translation-like factor eIF4AIII is recruited to the mRNA during splicing and functions in nonsense-mediated decay (2004) (187)
TIF4631 and TIF4632: two yeast genes encoding the high-molecular-weight subunits of the cap-binding protein complex (eukaryotic initiation factor 4F) contain an RNA recognition motif-like sequence and carry out an essential function (1993) (187)
mRNA translation: influence of the 5' and 3' untranslated regions. (1994) (187)
Reconstitution reveals the functional core of mammalian eIF3 (2007) (187)
General RNA binding proteins render translation cap dependent. (1996) (187)
Distinct perturbation of the translatome by the antidiabetic drug metformin (2012) (186)
A region rich in aspartic acid, arginine, tyrosine, and glycine (DRYG) mediates eukaryotic initiation factor 4B (eIF4B) self-association and interaction with eIF3 (1996) (185)
1 Origins and Principles of Translational Control (2007) (185)
Structural and functional analysis of the ribosome landing pad of poliovirus type 2: in vivo translation studies (1991) (184)
Starvation and oxidative stress resistance in Drosophila are mediated through the eIF4E-binding protein, d4E-BP. (2005) (183)
Translational control of immune responses: from transcripts to translatomes (2014) (183)
The mRNA 5' cap-binding protein, eIF-4E, cooperates with v-myc or E1A in the transformation of primary rodent fibroblasts (1992) (182)
HuR protein attenuates miRNA-mediated repression by promoting miRISC dissociation from the target RNA (2012) (181)
Phosphorylation of Eukaryotic Translation Initiation Factor 4E Is Critical for Growth (2002) (181)
Double-stranded-RNA-dependent protein kinase and TAR RNA-binding protein form homo- and heterodimers in vivo. (1995) (180)
Signaling control of mRNA translation in cancer pathogenesis (2004) (180)
Therapeutic inhibition of MAP kinase interacting kinase blocks eukaryotic initiation factor 4E phosphorylation and suppresses outgrowth of experimental lung metastases. (2011) (179)
mTOR signaling: implications for cancer and anticancer therapy (2005) (177)
Phospho-dependent phase separation of FMRP and CAPRIN1 recapitulates regulation of translation and deadenylation (2019) (177)
Activation of double-stranded RNA-dependent kinase (dsl) by the TAR region of HIV-1 mRNA: A novel translational control mechanism (1989) (176)
La Autoantigen Is Necessary for Optimal Function of the Poliovirus and Hepatitis C Virus Internal Ribosome Entry Site In Vivo and In Vitro (2004) (176)
Translational Control in Cancer. (2018) (173)
ATF4-mediated induction of 4E-BP1 contributes to pancreatic beta cell survival under endoplasmic reticulum stress. (2008) (173)
FRAP/mTOR is required for proliferation and patterning during embryonic development in the mouse (2001) (171)
Signalling to eIF4E in cancer (2015) (169)
The eIF4G-eIF4E complex is the target for direct cleavage by the rhinovirus 2A proteinase (1996) (168)
Constitutive mTOR activation in TSC mutants sensitizes cells to energy starvation and genomic damage via p53 (2007) (167)
Involvement of eukaryotic initiation factor 4A in the cap recognition process. (1983) (167)
Leishmania repression of host translation through mTOR cleavage is required for parasite survival and infection. (2011) (166)
Translational control of programmed cell death: eukaryotic translation initiation factor 4E blocks apoptosis in growth-factor-restricted fibroblasts with physiologically expressed or deregulated Myc (1996) (164)
Dual Interactions of the Translational Repressor Paip2 with Poly(A) Binding Protein (2001) (162)
Translational homeostasis via the mRNA cap-binding protein, eIF4E. (2012) (160)
La autoantigen alleviates translational repression by the 5' leader sequence of the human immunodeficiency virus type 1 mRNA (1994) (160)
Opposite Translational Control of GLUT1 and GLUT4 Glucose Transporter mRNAs in Response to Insulin (1999) (159)
Mutational analysis of the 5′ non‐coding region of human immunodeficiency virus type 1: effects of secondary structure on translation. (1988) (158)
Eukaryotic Translation Initiation Factor 4AIII (eIF4AIII) Is Functionally Distinct from eIF4AI and eIF4AII (1999) (158)
Pharmacogenetic Inhibition of eIF4E-Dependent Mmp9 mRNA Translation Reverses Fragile X Syndrome-like Phenotypes (2014) (158)
Control of the interferon-induced 68-kilodalton protein kinase by the HIV-1 tat gene product. (1990) (158)
Cell-cycle-dependent translational control. (2001) (158)
Internal translation initiation on poliovirus RNA: further characterization of La function in poliovirus translation in vitro (1994) (157)
Poliovirus mutant that does not selectively inhibit host cell protein synthesis (1985) (155)
Poly(A)-binding protein interaction with elF4G stimulates picornavirus IRES-dependent translation. (2001) (155)
Cap-Dependent Translational Inhibition Establishes Two Opposing Morphogen Gradients in Drosophila Embryos (2006) (154)
A Novel 4EHP-GIGYF2 Translational Repressor Complex Is Essential for Mammalian Development (2012) (152)
UNR, a new partner of poly(A)-binding protein, plays a key role in translationally coupled mRNA turnover mediated by the c-fos major coding-region determinant. (2004) (151)
Eukaryotic Initiation Factor 4GII (eIF4GII), but Not eIF4GI, Cleavage Correlates with Inhibition of Host Cell Protein Synthesis after Human Rhinovirus Infection (1999) (150)
Metformin ameliorates core deficits in a mouse model of fragile X syndrome (2017) (149)
Poly(A)-Binding Protein-Interacting Protein 1 Binds to Eukaryotic Translation Initiation Factor 3 To Stimulate Translation (2008) (148)
Ras mediates translation initiation factor 4E-induced malignant transformation. (1992) (147)
eIF4E/4E-BP ratio predicts the efficacy of mTOR targeted therapies. (2012) (147)
Phosphoproteomic Analysis Identifies Grb10 as an mTORC1 Substrate That Negatively Regulates Insulin Signaling (2011) (146)
The Organizing Principles of Eukaryotic Ribosome Recruitment. (2019) (145)
Paip1 Interacts with Poly(A) Binding Protein through Two Independent Binding Motifs (2002) (145)
Poliovirus 2A Protease Induces Apoptotic Cell Death (2000) (144)
6 Regulation of Ribosomal Recruitment in Eukaryotes (2000) (144)
Structure-Activity Analysis of Niclosamide Reveals Potential Role for Cytoplasmic pH in Control of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling* (2012) (143)
14-3-3sigma controls mitotic translation to facilitate cytokinesis. (2007) (143)
The E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAs (2017) (141)
Translational control of tumor immune escape via the eIF4F–STAT1–PD-L1 axis in melanoma (2018) (140)
Activation of the p70 S6 Kinase and Phosphorylation of the 4E-BP1 Repressor of mRNA Translation by Type I Interferons* (2003) (139)
Interaction of eIF4G with poly(A)-binding protein stimulates translation and is critical for Xenopus oocyte maturation (2000) (138)
Eukaryotic Translation Initiation Factor 4EAvailability Controls the Switch between Cap-Dependent andInternal Ribosomal Entry Site-MediatedTranslation (2005) (138)
Signaling from Akt to FRAP/TOR Targets both 4E-BP andS6K in Drosophilamelanogaster (2003) (134)
Host Translation at the Nexus of Infection and Immunity (2012) (133)
Cloning and Characterization of 4EHP, a Novel Mammalian eIF4E-related Cap-binding Protein* (1998) (133)
Regulation of translation by poliovirus. (1987) (133)
Eap1p, a Novel Eukaryotic Translation Initiation Factor 4E-Associated Protein in Saccharomyces cerevisiae (2000) (133)
Nuclear Eukaryotic Initiation Factor 4e (Eif4e) Colocalizes with Splicing Factors in Speckles (2000) (132)
Picornavirus RNA translation: roles for cellular proteins. (2000) (130)
Control of Cell Survival and Proliferation by Mammalian Eukaryotic Initiation Factor 4B (2010) (130)
Regulation of translation and cell growth by eIF-4E. (1994) (129)
Phosphorylation of eIF4E attenuates its interaction with mRNA 5' cap analogs by electrostatic repulsion: intein-mediated protein ligation strategy to obtain phosphorylated protein. (2003) (129)
Translation deregulation in human disease (2018) (129)
N1-methyl-pseudouridine in mRNA enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density (2017) (129)
Translation factors as effectors of cell growth and tumorigenesis. (1993) (128)
Vesicular stomatitis virus oncolysis is potentiated by impairing mTORC1-dependent type I IFN production (2010) (127)
eIF4B controls survival and proliferation and is regulated by proto-oncogenic signaling pathways (2010) (126)
Regulation of poly(A)-binding protein through PABP-interacting proteins. (2006) (126)
Internal binding of eucaryotic ribosomes on poliovirus RNA: translation in HeLa cell extracts (1989) (126)
MicroRNAs trigger dissociation of eIF4AI and eIF4AII from target mRNAs in humans. (2014) (126)
Decoying the cap- mRNA degradation system by a double-stranded RNA virus and poly(A)- mRNA surveillance by a yeast antiviral system (1995) (125)
The p46 subunit of eukaryotic initiation factor (eIF)-4F exchanges with eIF-4A. (1993) (125)
IRF-1 induced cell growth inhibition and interferon induction requires the activity of the protein kinase PKR. (1995) (125)
Structural requirements for trans activation of human immunodeficiency virus type 1 long terminal repeat-directed gene expression by tat: importance of base pairing, loop sequence, and bulges in the tat-responsive sequence (1990) (124)
Expression of a translationally regulated, dominant-negative CCAAT/enhancer-binding protein beta isoform and up-regulation of the eukaryotic translation initiation factor 2alpha are correlated with neoplastic transformation of mammary epithelial cells. (1996) (123)
Regulatory Effects of Mammalian Target of Rapamycin-activated Pathways in Type I and II Interferon Signaling* (2007) (122)
Translational Control of Entrainment and Synchrony of the Suprachiasmatic Circadian Clock by mTOR/4E-BP1 Signaling (2013) (121)
Cap-dependent RNA splicing in a HeLa nuclear extract. (1985) (120)
Proteolysis of the p220 component of the cap-binding protein complex is not sufficient for complete inhibition of host cell protein synthesis after poliovirus infection (1987) (119)
Translational control of the activation of transcription factor NF-κB and production of type I interferon by phosphorylation of the translation factor eIF4E (2012) (119)
Control of eIF4E cellular localization by eIF4E-binding proteins, 4E-BPs. (2008) (118)
Mutational analysis of upstream AUG codons of poliovirus RNA (1988) (117)
p53-dependent translational control of senescence and transformation via 4E-BPs. (2009) (116)
Purification of a factor that restores translation of vesicular stomatitis virus mRNA in extracts from poliovirus-infected HeLa cells. (1980) (116)
4E binding proteins inhibit the translation factor eIF4E without folded structure. (1998) (116)
Novel Translational Control in Arc-dependent Long Term Potentiation Consolidation in Vivo* (2009) (116)
The translation initiation factor eIF-4B contains an RNA-binding region that is distinct and independent from its ribonucleoprotein consensus sequence. (1994) (115)
Translational Control of the Antiapoptotic Function of Ras* (2000) (115)
Structural basis of ligand recognition by PABC, a highly specific peptide‐binding domain found in poly(A)‐binding protein and a HECT ubiquitin ligase (2004) (114)
Sequence of reovirus haemagglutinin predicts a coiled-coil structure (1985) (113)
Human DDX6 effects miRNA-mediated gene silencing via direct binding to CNOT1 (2014) (112)
Translational Homeostasis: Eukaryotic Translation Initiation Factor 4E Control of 4E-Binding Protein 1 and p70 S6 Kinase Activities (1999) (112)
An efficient mammalian cell-free translation system supplemented with translation factors. (2006) (111)
ATP/Mg++-dependent cross-linking of cap binding proteins to the 5' end of eukaryotic mRNA. (1981) (111)
Mechanism of Translation Initiation in Eukaryotes (2013) (111)
A mechanism of translational repression by competition of Paip2 with eIF4G for poly(A) binding protein (PABP) binding. (2006) (109)
Translation in mammalian cells of a gene linked to the poliovirus 5' noncoding region. (1988) (109)
Structural insights into the human GW182-PABC interaction in microRNA-mediated deadenylation (2010) (109)
The protein kinase PKR: a molecular clock that sequentially activates survival and death programs (2004) (108)
Poly(A) binding protein (PABP) homeostasis is mediated by the stability of its inhibitor, Paip2 (2006) (108)
The helicase protein DHX29 promotes translation initiation, cell proliferation, and tumorigenesis (2009) (108)
Dual regulation of translation initiation and peptide chain elongation during BDNF‐induced LTP in vivo: evidence for compartment‐specific translation control (2006) (108)
Control of translation by the target of rapamycin proteins. (2001) (107)
Molecular and genetic crosstalks between mTOR and ERRα are key determinants of rapamycin-induced nonalcoholic fatty liver. (2013) (106)
ERK and mTOR Signaling Couple β-Adrenergic Receptors to Translation Initiation Machinery to Gate Induction of Protein Synthesis-dependent Long-term Potentiation* (2007) (106)
In vitro mutational analysis of cis-acting RNA translational elements within the poliovirus type 2 5' untranslated region (1991) (106)
Translational Control of Cell Fate: Availability of Phosphorylation Sites on Translational Repressor 4E-BP1 Governs Its Proapoptotic Potency (2002) (106)
Phosphorylation of eIF-4E on Serine 209 by Protein Kinase C Is Inhibited by the Translational Repressors, 4E-binding Proteins (*) (1996) (105)
Pervasive and cooperative deadenylation of 3'UTRs by embryonic microRNA families. (2010) (105)
RNA unwinding in translation: assembly of helicase complex intermediates comprising eukaryotic initiation factors eIF-4F and eIF-4B (1991) (105)
Requirement of RNA Binding of Mammalian Eukaryotic Translation Initiation Factor 4GI (eIF4GI) for Efficient Interaction of eIF4E with the mRNA Cap (2008) (104)
The mTOR pathway in hepatic malignancies (2013) (104)
Effect of viral infection on host protein synthesis and mRNA association with the cytoplasmic cytoskeletal structure (1985) (104)
New Ways of Initiating Translation in Eukaryotes? (2001) (104)
G3BP1 promotes stress-induced RNA granule interactions to preserve polyadenylated mRNA (2015) (102)
1 Origins and Targets of Translational Control (1996) (101)
The ELAV protein HuD stimulates cap-dependent translation in a Poly(A)- and eIF4A-dependent manner. (2009) (99)
Loss of mTORC1 signalling impairs β-cell homeostasis and insulin processing (2017) (99)
Inhibition of Myc-dependent apoptosis by eukaryotic translation initiation factor 4E requires cyclin D1 (2000) (99)
A mammalian translation initiation factor can substitute for its yeast homologue in vivo. (1989) (98)
Principles of Translational Control. (2018) (97)
The Saccharomyces cerevisiae translation initiation factor Tif3 and its mammalian homologue, eIF‐4B, have RNA annealing activity. (1995) (97)
The integrity of the stem structure of human immunodeficiency virus type 1 Tat-responsive sequence of RNA is required for interaction with the interferon-induced 68,000-Mr protein kinase (1991) (97)
Translation is actively regulated during the differentiation of CD8+ effector T cells (2017) (96)
Differential stimulation of capped mRNA translation in vitro by cap binding protein (1980) (96)
UHRF 1 Plays a Role in Maintaining DNA Methylation in Mammalian Cells (96)
Phosphorylation of eukaryotic translation initiation factor 4E is increased in Src-transformed cell lines (1991) (94)
Cleavage of Eukaryotic Translation Initiation Factor 4GII within Foot-and-Mouth Disease Virus-Infected Cells: Identification of the L-Protease Cleavage Site In Vitro (2004) (94)
8 mRNA 5′ Cap-binding Protein elF4E and Control of Cell Growth (1996) (94)
Protein analysis by mass spectrometry and sequence database searching: Tools for cancer research in the post‐genomic era (1999) (93)
The La autoantigen contains a dimerization domain that is essential for enhancing translation (1997) (93)
The Fragile X Syndrome Protein Represses Activity-Dependent Translation through CYFIP 1 , a New 4 EBP (2008) (93)
Translation in Saccharomyces cerevisiae: initiation factor 4E-dependent cell-free system (1989) (92)
The MNK–eIF4E Signaling Axis Contributes to Injury-Induced Nociceptive Plasticity and the Development of Chronic Pain (2017) (92)
Unique translation initiation of mRNAs-containing TISU element (2011) (91)
Behavioral alterations in mice lacking the translation repressor 4E-BP2 (2007) (91)
Resistance to Vesicular Stomatitis Virus Infection Requires a Functional Cross Talk between the Eukaryotic Translation Initiation Factor 2α Kinases PERK and PKR (2004) (91)
TOR Is Required for the Retrograde Regulation of Synaptic Homeostasis at the Drosophila Neuromuscular Junction (2012) (90)
Phosphorylation of translation initiation factor eIF-4E is induced in a ras-dependent manner during nerve growth factor-mediated PC12 cell differentiation (1992) (87)
When translation meets metabolism: multiple links to diabetes. (2003) (87)
Influenza Virus mRNA Translation Revisited: Is the eIF4E Cap-Binding Factor Required for Viral mRNA Translation? (2007) (87)
Differential efficiencies of in vitro translation of mouse c-myc transcripts differing in the 5' untranslated region. (1985) (86)
An efficient strategy to isolate full-length cDNAs based on an mRNA cap retention procedure (CAPture) (1995) (86)
Inactivation of cap-binding proteins accompanies the shut-off of host protein synthesis by poliovirus. (1982) (86)
Synthetic analogue of rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and caspase-12. (2009) (86)
Photochemical cross-linking of cap binding proteins to eucaryotic mRNAs: effect of mRNA 5' secondary structure (1985) (85)
Insulin regulation of protein translation repressor 4E-BP1, an eIF4E-binding protein, in renal epithelial cells. (2001) (85)
Requirement for Akt (Protein Kinase B) in Insulin-induced Activation of Glycogen Synthase and Phosphorylation of 4E-BP1 (PHAS-1)* (1999) (85)
Mechanisms governing the control of mRNA translation (2010) (84)
In vitro RNA selection identifies RNA ligands that specifically bind to eukaryotic translation initiation factor 4B: the role of the RNA remotif. (1996) (84)
RNA aptamers to initiation factor 4A helicase hinder cap-dependent translation by blocking ATP hydrolysis. (2003) (84)
The involvement of mRNA secondary structure in protein synthesis. (1987) (84)
High-level synthesis in Escherichia coli of functional cap-binding eukaryotic initiation factor eIF-4E and affinity purification using a simplified cap-analog resin. (1988) (84)
mTOR signaling: implications for cancer and anticancer therapy. (2007) (84)
Synergistic effects between analogs of DNA and RNA improve the potency of siRNA-mediated gene silencing (2010) (83)
Translation initiation factors induce DNA synthesis and transform NIH 3T3 cells. (1990) (83)
Identification of differential translation in genome wide studies (2010) (81)
Cleavage of eukaryotic translation initiation factor 4GII correlates with translation inhibition during apoptosis (2000) (81)
mRNA translation and energy metabolism in cancer: the role of the MAPK and mTORC1 pathways. (2011) (80)
Regulatable expression of the interferon-induced double-stranded RNA dependent protein kinase PKR induces apoptosis and fas receptor expression. (1999) (80)
Arabidopsis Argonaute MID domains use their nucleotide specificity loop to sort small RNAs (2012) (80)
mTORC1 inhibition induces pain via IRS-1-dependent feedback activation of ERK (2013) (79)
A lysine substitution in the ATP-binding site of eucaryotic initiation factor 4A abrogates nucleotide-binding activity (1989) (79)
X-ray structure of the human hyperplastic discs protein: An ortholog of the C-terminal domain of poly(A)-binding protein (2001) (79)
Regulation of SOCS-1 Expression by Translational Repression* (2000) (79)
An efficient system for cap- and poly(A)-dependent translation in vitro. (2004) (79)
5'-Conformation of capped alfalfa mosaic virus ribonucleic acid 4 may reflect its independence of the cap structure or of cap-binding protein for efficient translation. (1983) (78)
DAP5 associates with eIF2β and eIF4AI to promote Internal Ribosome Entry Site driven translation (2015) (78)
Postnatal deamidation of 4E-BP2 in brain enhances its association with raptor and alters kinetics of excitatory synaptic transmission. (2010) (78)
ATP hydrolysis by initiation factor 4A is required for translation initiation in Saccharomyces cerevisiae. (1992) (78)
cis-acting translational effects of the 5' noncoding region of c-myc mRNA (1988) (77)
Probing the function of the eucaryotic 5′ cap structure by using a monoclonal antibody directed against cap-binding proteins (1981) (77)
Interaction of the eukaryotic initiation factor 4E with 4E-BP2 at a dynamic bipartite interface. (2013) (76)
Reovirus mRNA can be covalently crosslinked via the 5' cap to proteins in initiation complexes. (1977) (76)
Translational tolerance of mitochondrial genes to metabolic energy stress involves TISU and eIF1-eIF4GI cooperation in start codon selection. (2015) (75)
Expression of the protein kinase PKR in modulated by IRF-1 and is reduced in 5q- associated leukemias. (1996) (74)
Anota: Analysis of Differential Translation in Genome-wide Studies (2011) (73)
Double-stranded RNA-dependent Protein Kinase Mediates c-Myc Suppression Induced by Type I Interferons* (1996) (73)
Understanding how miRNAs post-transcriptionally regulate gene expression. (2010) (73)
General RNA‐binding proteins have a function in poly(A)‐binding protein‐dependent translation (2009) (73)
Translational Control Mechanisms in Long-lasting Synaptic Plasticity and Memory* (2010) (72)
Analysis of terminal structures of RNA from potato virus X. (1978) (72)
The poly(A)-binding protein partner Paip2a controls translation during late spermiogenesis in mice. (2010) (72)
A cell cycle-dependent internal ribosome entry site (2000) (70)
Cap-binding protein 4EHP effects translation silencing by microRNAs (2017) (70)
Nociceptor Translational Profiling Reveals the Ragulator-Rag GTPase Complex as a Critical Generator of Neuropathic Pain (2018) (69)
Epiregulin and EGFR interactions are involved in pain processing. (2017) (69)
Eukaryotic Translation Initiation Factor 4E Availability Controls the Switch between Cap-Dependent and Internal Ribosomal Entry Site-Mediated Translation† (2005) (69)
Translational efficiency of poliovirus mRNA: mapping inhibitory cis-acting elements within the 5' noncoding region (1988) (68)
Seasonal and state-dependent changes of eIF4E and 4E-BP1 during mammalian hibernation: implications for the control of translation during torpor. (2004) (67)
Adenovirus infection inactivates the translational inhibitors 4E-BP1 and 4E-BP2. (1997) (67)
Distinct Translational Control in CD4+ T Cell Subsets (2013) (67)
The Human Homologue of the Yeast Prt1 Protein Is an Integral Part of the Eukaryotic Initiation Factor 3 Complex and Interacts with p170* (1997) (67)
Regulation of the Rapamycin and FKBP-Target 1/Mammalian Target of Rapamycin and Cap-dependent Initiation of Translation by the c-Abl Protein-tyrosine Kinase* (2000) (67)
The number of positively charged amino acids in the basic domain of Tat is critical for trans-activation and complex formation with TAR RNA. (1991) (66)
The rate of protein synthesis in hematopoietic stem cells is limited partly by 4E-BPs (2016) (66)
Control of Synaptic Plasticity and Memory via Suppression of Poly(A)-Binding Protein (2013) (66)
Translational Silencing of Ceruloplasmin Requires the Essential Elements of mRNA Circularization: Poly(A) Tail, Poly(A)-Binding Protein, and Eukaryotic Translation Initiation Factor 4G (2001) (66)
Positive heat capacity change upon specific binding of translation initiation factor eIF4E to mRNA 5' cap. (2002) (66)
Internal initiation of picornavirus RNA translation (1993) (66)
The effect of poliovirus proteinase 2Apro expression on cellular metabolism. Inhibition of DNA replication, RNA polymerase II transcription, and translation. (1991) (66)
Demonstration in vitro that eucaryotic initiation factor 3 is active but that a cap-binding protein complex is inactive in poliovirus-infected HeLa cells (1984) (65)
Inactivation of the mTORC1-Eukaryotic Translation Initiation Factor 4E Pathway Alters Stress Granule Formation (2013) (65)
Tissue distribution, genomic structure, and chromosome mapping of mouse and human eukaryotic initiation factor 4E-binding proteins 1 and 2. (1996) (64)
A translational rheostat for RFLAT-1 regulates RANTES expression in T lymphocytes. (2002) (63)
Shared protein components of SINE RNPs. (2002) (63)
Translational control in the tumor microenvironment promotes lung metastasis: Phosphorylation of eIF4E in neutrophils (2018) (63)
Identification of a new polypeptide coded by reovirus gene S1 (1985) (63)
Light-regulated translational control of circadian behavior by eIF4E phosphorylation (2015) (63)
Weak binding affinity of human 4EHP for mRNA cap analogs. (2007) (62)
Purification and characterization of protein synthesis initiation factor eIF-4E from the yeast Saccharomyces cerevisiae. (1985) (62)
Regulation of translation initiation factor gene expression during human T cell activation. (1992) (61)
Two structurally atypical HEAT domains in the C-terminal portion of human eIF4G support binding to eIF4A and Mnk1. (2006) (61)
Disruption of I kappa B alpha regulation by antisense RNA expression leads to malignant transformation. (1994) (61)
Conserved tertiary structural elements in the 5' nontranslated region of cardiovirus, aphthovirus and hepatitis A virus RNAs. (1993) (60)
Translational control of ornithine aminotransferase. Modulation by initiation factor eIF-4E. (1991) (60)
Mapping of Escherichia coli ribosomal components involved in peptidyl transferase activity. (1973) (60)
Translational Control in Stem Cells (2019) (60)
Conserved nucleotides in the TAR RNA stem of human immunodeficiency virus type 1 are critical for Tat binding and trans activation: model for TAR RNA tertiary structure (1992) (59)
Conserved tertiary structure elements in the 5′ untranslated region of human enteroviruses and rhinoviruses (1992) (59)
Identification and characterization of cap-binding proteins from yeast. (1989) (58)
Akt phosphorylation of La regulates specific mRNA translation in glial progenitors (2009) (58)
S6K-STING interaction regulates cytosolic DNA–mediated activation of the transcription factor IRF3 (2016) (58)
Translational control of gene expression: a molecular switch for memory storage. (2008) (58)
Overexpression of initiation factor eIF-4E does not relieve the translational repression of ribosomal protein mRNAs in quiescent cells. (1995) (58)
Blocking the eIF2α Kinase (PKR) Enhances Positive and Negative Forms of Cortex-Dependent Taste Memory (2013) (58)
Gene Fusion and Overlapping Reading Frames in the Mammalian Genes for 4E-BP3 and MASK* (2003) (57)
Degradation of Newly Synthesized Polypeptides by Ribosome-Associated RACK1/c-Jun N-Terminal Kinase/Eukaryotic Elongation Factor 1A2 Complex (2013) (57)
Toward a genome-wide landscape of translational control. (2013) (56)
Translational control and the cancer cell response to stress. (2017) (56)
Cap-dependent translation and control of the cell cycle. (2003) (55)
Rapamycin stimulates viral protein synthesis and augments the shutoff of host protein synthesis upon picornavirus infection (1996) (55)
Helicases and RNA unwinding in translation (1993) (55)
eIF4E/4E-BP dissociation and 4E-BP degradation in the first mitotic division of the sea urchin embryo. (2003) (55)
Remarks on the mechanism of ribosome binding to eukaryotic mRNAs. (1993) (55)
Differential Inhibition of Protein Translation Machinery by Curcumin in Normal, Immortalized, and Malignant Oral Epithelial Cells (2010) (54)
Critical chemical features in trans-acting-responsive RNA are required for interaction with human immunodeficiency virus type 1 Tat protein (1991) (54)
Site-directed mutagenesis of the tryptophan residues in yeast eukaryotic initiation factor 4E. Effects on cap binding activity. (1988) (54)
Altered biochemical properties of actin in normal skin fibroblasts from individuals predisposed to dominantly inherited cancers. (1986) (53)
Signal transduction and regulation of translation initiation. (1992) (53)
Functional characterization of eukaryotic mRNA cap binding protein complex: effects on translation of capped and naturally uncapped RNAs. (1984) (53)
A Potential Role for Extracellular Signal-regulated Kinases in Prostaglandin F2α-induced Protein Synthesis in Smooth Muscle Cells* (1999) (53)
Regulation of poly(A) binding protein function in translation: Characterization of the Paip2 homolog, Paip2B. (2006) (52)
Control of embryonic stem cell self-renewal and differentiation via coordinated alternative splicing and translation of YY2 (2016) (52)
Isolation and structural characterization of cap-binding proteins from poliovirus-infected HeLa cells (1985) (51)
Capped mRNAs with Reduced Secondary Structure Can Function in Extracts from Poliovirus-Infected Cells (1982) (51)
Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E (2018) (51)
The 4E-BP–eIF4E axis promotes rapamycin-sensitive growth and proliferation in lymphocytes (2016) (51)
Poliovirus translation. (1990) (51)
His-154 is involved in the linkage of the Saccharomyces cerevisiae L-A double-stranded RNA virus Gag protein to the cap structure of mRNAs and is essential for M1 satellite virus expression (1994) (51)
Rheb (Ras Homologue Enriched in Brain)-dependent Mammalian Target of Rapamycin Complex 1 (mTORC1) Activation Becomes Indispensable for Cardiac Hypertrophic Growth after Early Postnatal Period* (2013) (50)
Regulation of Gene Expression in Animal Viruses (1993) (50)
eIF4E association with 4E-BP decreases rapidly following fertilization in sea urchin. (2001) (50)
Rapamycin and Wortmannin Enhance Replication of a Defective Encephalomyocarditis Virus (1998) (50)
Current Status and Challenges Associated with Targeting mTOR for Cancer Therapy (2012) (49)
Cell-Free Synthesis of Encephalomyocarditis Virus (2003) (49)
The Kinase Insert Domain of Interferon-induced Protein Kinase PKR Is Required for Activity but Not for Interaction with the Pseudosubstrate K3L* (1996) (49)
IL-15 Can Signal via IL-15Rα, JNK, and NF-κB To Drive RANTES Production by Myeloid Cells (2012) (49)
mRNA secondary structure as a determinant in cap recognition and initiation complex formation. ATP-Mg2+ independent cross-linking of cap binding proteins to m7I-capped inosine-substituted reovirus mRNA. (1983) (49)
Transdominant mutants of I kappa B alpha block Tat-tumor necrosis factor synergistic activation of human immunodeficiency virus type 1 gene expression and virus multiplication (1996) (49)
Autism-Misregulated eIF4G Microexons Control Synaptic Translation and Higher Order Cognitive Functions. (2020) (49)
Metformin inhibits RAN translation through PKR pathway and mitigates disease in C9orf72 ALS/FTD mice (2020) (49)
Translational regulation of the mammalian growth-related protein P23: involvement of eIF-4E. (1994) (49)
Selective Modification of Eukaryotic Initiation Factor 4F (eIF4F) at the Onset of Cell Differentiation: Recruitment of eIF4GII and Long-Lasting Phosphorylation of eIF4E (2004) (48)
Inhibition of eukaryotic translation by nucleoside 5'-monophosphate analogues of mRNA 5'-cap: changes in N7 substituent affect analogue activity. (1989) (48)
Multiple mRNAs encode the murine translation initiation factor eIF-4E. (1991) (47)
The Interferon-inducible Protein Kinase PKR Modulates the Transcriptional Activation of Immunoglobulin κ Gene (*) (1995) (47)
Measures and countermeasures in the modulation of initiation factor activities by viruses. (1990) (47)
Metformin for Treatment of Fragile X Syndrome and Other Neurological Disorders. (2019) (47)
Tat-dependent adenosine-to-inosine modification of wild-type transactivation response RNA. (1991) (47)
Persistent Transcription- and Translation-Dependent Long-Term Potentiation Induced by mGluR1 in Hippocampal Interneurons (2009) (46)
The coat protein of the yeast double-stranded RNA virus L-A attaches covalently to the cap structure of eukaryotic mRNA (1992) (46)
Phenethyl isothiocyanate, a cancer chemopreventive constituent of cruciferous vegetables, inhibits cap-dependent translation by regulating the level and phosphorylation of 4E-BP1. (2007) (45)
Control of Translation and miRNA-Dependent Repression by a Novel Poly(A) Binding Protein, hnRNP-Q (2013) (45)
Selective Regulation of GluA Subunit Synthesis and AMPA Receptor-Mediated Synaptic Function and Plasticity by the Translation Repressor 4E-BP2 in Hippocampal Pyramidal Cells (2013) (45)
Differential regulation of 4E-BP1 and 4E-BP2, two repressors of translation initiation, during human myeloid cell differentiation. (1999) (45)
RAPping production of type I interferon in pDCs through mTOR (2008) (44)
Cap binding complexes and cellular growth control. (1995) (44)
Unusual folding regions and ribosome landing pad within hepatitis C virus and pestivirus RNAs. (1995) (44)
Multifaceted regulation of somatic cell reprogramming by mRNA translational control. (2014) (44)
RNA aptamers to mammalian initiation factor 4G inhibit cap-dependent translation by blocking the formation of initiation factor complexes. (2006) (44)
The Drosophila Poly(A) Binding Protein-Interacting Protein, dPaip2, Is a Novel Effector of Cell Growth (2004) (44)
15 Translational Control in Cancer Development and Progression (2007) (44)
Microtubule disruption synergizes with oncolytic virotherapy by inhibiting interferon translation and potentiating bystander killing (2015) (44)
eIF2α controls memory consolidation via excitatory and somatostatin neurons (2020) (43)
Translation is actively regulated during effector CD8+ T cell differentiation (2017) (43)
Introduction to Translation (2013) (43)
Regulation of protein synthesis by IGF-I in proximal tubular epithelial cells. (2002) (43)
Antidepressant actions of ketamine engage cell-specific translation via eIF4E (2020) (43)
Norepinephrine triggers metaplasticity of LTP by increasing translation of specific mRNAs (2015) (43)
The role of the La autoantigen in internal initiation. (1995) (42)
Picornavirus RNA translation continues to surprise. (1991) (42)
High affinity RNA for mammalian initiation factor 4E interferes with mRNA-cap binding and inhibits translation. (2005) (41)
Parallel measurement of dynamic changes in translation rates in single cells (2013) (41)
Ablation of 4E-BP1/2 Prevents Hyperglycemia-Mediated Induction of VEGF Expression in the Rodent Retina and in Müller Cells in Culture (2010) (41)
A threonyl-tRNA synthetase-mediated translation initiation machinery (2019) (41)
Single-molecule kinetics of the eukaryotic initiation factor 4AI upon RNA unwinding. (2014) (41)
Neuronal Regulation of eIF2α Function in Health and Neurological Disorders. (2018) (41)
Circular dichroism and fluorescence studies on protein synthesis initiation factor eIF-4E and two mutant forms from the yeast Saccharomyces cerevisiae. (1988) (41)
Poly(A)-Binding Protein Binds to A-Rich Sequences via RNA-Binding Domains 1+2 and 3+4 (2006) (41)
Evidence for a tumor promoting effect of high-fat diet independent of insulin resistance in HER2/Neu mammary carcinogenesis (2010) (41)
Regulation of eukaryotic translation initiation factor expression during T-cell activation. (1993) (40)
Phosphorylation of Mnk1 by Caspase-activated Pak2/γ-PAK Inhibits Phosphorylation and Interaction of eIF4G with Mnk* (2004) (40)
Translational regulatory mechanisms in synaptic plasticity and memory storage. (2009) (40)
4E-BP1 Is a Tumor Suppressor Protein Reactivated by mTOR Inhibition in Head and Neck Cancer. (2019) (40)
Prokaryotic and eukaryotic translation factors (1996) (40)
Structural analysis of 5′‐mRNA–cap interactions with the human AGO2 MID domain (2011) (40)
Vesicular Stomatitis Virus Oncolysis of T Lymphocytes Requires Cell Cycle Entry and Translation Initiation (2008) (39)
The eukaryotic initiation factor eIF4H facilitates loop-binding, repetitive RNA unwinding by the eIF4A DEAD-box helicase (2012) (39)
Interaction of a limited set of proteins with different mRNAs and protection of 5'-caps against pyrophosphatase digestion in initiation complexes (1979) (39)
Alternatively Spliced Transcripts from the Drosophila eIF4E Gene Produce Two Different Cap-binding Proteins* (1996) (39)
Fibronectin controls cap-dependent translation through beta1 integrin and eukaryotic initiation factors 4 and 2 coordinated pathways. (2005) (39)
Preferential stimulation of rabbit α globin mRNA translation by a cap-binding protein complex (1984) (39)
Angiotensin II Stimulates Phosphorylation of the Translational Repressor 4E-binding Protein 1 by a Mitogen-activated Protein Kinase-independent Mechanism* (1997) (38)
Inhibition of Group I Metabotropic Glutamate Receptors Reverses Autistic-Like Phenotypes Caused by Deficiency of the Translation Repressor eIF4E Binding Protein 2 (2015) (38)
Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic β cells (2014) (37)
LRRK2 regulates retrograde synaptic compensation at the Drosophila neuromuscular junction (2016) (36)
Angiotensin II induces phosphorylation of eukaryotic protein synthesis initiation factor 4E in vascular smooth muscle cells. (1994) (36)
Inducible costimulator facilitates T-dependent B cell activation by augmenting IL-4 translation. (2014) (36)
Translation initiation factors that function as RNA helicases from mammals, plants and yeast. (1990) (36)
Phosphorylation Screening Identifies Translational Initiation Factor 4GII as an Intracellular Target of Ca2+/Calmodulin-dependent Protein Kinase I* (2003) (36)
Human Rhinovirus 2A Proteinase Cleavage Sites in Eukaryotic Initiation Factors (eIF) 4GI and eIF4GII Are Different (2003) (36)
Eukaryotic initiation factor 4E-3 is essential for meiotic chromosome segregation, cytokinesis and male fertility in Drosophila (2012) (36)
Translation initiation factor-dependent extracts from Saccharomyces cerevisiae. (1990) (36)
Phosphorylation of eIF4E Confers Resistance to Cellular Stress and DNA-Damaging Agents through an Interaction with 4E-T: A Rationale for Novel Therapeutic Approaches (2015) (35)
Translational control of ERK signaling through miRNA/4EHP-directed silencing (2018) (35)
Modulation of 4E-BP1 Function as a Critical Determinant of Enzastaurin-Induced Apoptosis (2010) (35)
Distinct Structural Elements and Internal Entry of Ribosomes in mRNA3 Encoded by Infectious Bronchitis Virus (1994) (35)
Beyond molecular tumor heterogeneity: protein synthesis takes control (2018) (35)
Interactions of the eIF-4F subunits in the yeast Saccharomyces cerevisiae. (1992) (34)
Photoaffinity labeling of the cap-binding protein complex with ATP/dATP. Differential labeling of free eukaryotic initiation factor 4A and the eukaryotic initiation factor 4A component of the cap-binding protein complex with [alpha-32P]ATP/dATP. (1985) (34)
Differential regulation of translation and eIF4E phosphorylation during human thymocyte maturation. (1998) (34)
mTOR kinase is needed for the development and stabilization of dendritic arbors in newly born olfactory bulb neurons (2016) (34)
Poliovirus translation: A paradigm for a novel initiation mechanism (1989) (34)
Translation control during prolonged mTORC1 inhibition mediated by 4E-BP3 (2016) (34)
Identification of nuclear cap specific proteins in HeLa cells. (1987) (34)
Structural analysis of the DAP5 MIF4G domain and its interaction with eIF4A. (2013) (33)
Embryonic-stage-dependent changes in the level of eIF4E-binding proteins during early development of sea urchin embryos (2005) (32)
mTOR signaling in VIP neurons regulates circadian clock synchrony and olfaction (2018) (32)
eIF2α phosphorylation controls thermal nociception (2016) (32)
Translational Control by the Eukaryotic Ribosome (2011) (32)
Gastrin induces phosphorylation of eIF4E binding protein 1 and translation initiation of ornithine decarboxylase mRNA (1998) (32)
Inhibitory interneurons mediate autism-associated behaviors via 4E-BP2 (2019) (32)
Protein Synthesis and Oncogenesis Meet Again (2006) (32)
Deficiency in mTORC1-controlled C/EBPβ-mRNA translation improves metabolic health in mice (2015) (32)
The eIF2α Kinase GCN2 Modulates Period and Rhythmicity of the Circadian Clock by Translational Control of Atf4 (2019) (32)
Control of Paip1-Eukayrotic Translation Initiation Factor 3 Interaction by Amino Acids through S6 Kinase (2014) (30)
Regulation of translation via TOR signaling: insights from Drosophila melanogaster. (2001) (30)
Lysergic acid diethylamide (LSD) promotes social behavior through mTORC1 in the excitatory neurotransmission (2021) (30)
Largen: a molecular regulator of mammalian cell size control. (2014) (29)
Signal transduction. Protein synthesis and oncogenesis meet again. (2006) (29)
Acute Fasting Regulates Retrograde Synaptic Enhancement through a 4E-BP-Dependent Mechanism (2016) (29)
Suppression of a temperature-sensitive cdc33 mutation of yeast by a multicopy plasmid expressing a Drosophila ribosomal protein. (1994) (29)
Translation of poliovirus mRNA. (1990) (29)
Translational control of nociception via 4E-binding protein 1 (2015) (28)
Nanopore detachment kinetics of poly(A) binding proteins from RNA molecules reveals the critical role of C-terminus interactions. (2012) (28)
Cell cycle-dependent translational control (2000) (27)
The eIF4E-binding proteins are modifiers of cytoplasmic eIF4E relocalization during the heat shock response. (2009) (27)
Role of Eukaryotic Messenger RNA Cap-Binding Protein in Regulation of Translation (1987) (27)
mTOR inhibitor efficacy is determined by the eIF4E/4E-BP ratio (2012) (26)
Poliovirus protease 3C (P3-7c) does not cleave P220 of the eucaryotic mRNA cap-binding protein complex (1985) (26)
Dependent Translation Initiation in Breast Cancer Cells − Metformin Inhibits Mammalian Target of Rapamycin (2007) (26)
Stimulation of picornavirus replication by the poly(A) tail in a cell-free extract is largely independent of the poly(A) binding protein (PABP). (2007) (26)
Ischemia-induced calpain activation causes eukaryotic (translation) initiation factor 4G1 (eIF4GI) degradation, protein synthesis inhibition, and neuronal death (2011) (26)
Identification of a region in 23S rRNA located at the peptidyl transferase center. (1975) (25)
Correction (1995) (25)
Metformin requires 4E-BPs to induce apoptosis and repress translation of Mcl-1 in hepatocellular carcinoma cells (2016) (25)
Proposing a mechanism of action for ataluren (2016) (25)
MNK inhibition sensitizes KRAS-mutant colorectal cancer to mTORC1 inhibition by reducing eIF4E phosphorylation and c-MYC expression. (2020) (24)
Nonspecific effect of m7GMP on protein-RNA interactions. (1978) (24)
Alternative splicing facilitates internal ribosome entry on the ornithine decarboxylase mRNA (2005) (24)
Role of 3′UTRs in the Translation of mRNAs Regulated by Oncogenic eIF4E—A Computational Inference (2009) (24)
Isolation of a yeast gene encoding a protein homologous to the human Tat-binding protein TBP-1. (1992) (24)
Granzyme B Inhibits Vaccinia Virus Production through Proteolytic Cleavage of Eukaryotic Initiation Factor 4 Gamma 3 (2011) (23)
In vitro translation in reovirus- and poliovirus-infected cell extracts. Effects of anti-cap binding protein monoclonal antibody. (1981) (23)
Regulation of Neuronal mRNA Translation by CaM-Kinase I Phosphorylation of eIF4GII (2012) (23)
Human eukaryotic translation initiation factor 4 G ( eIF 4 G ) recruits Mnk 1 to phosphorylate eIF 4 E (2013) (23)
Akt‐dependent Skp2 mRNA translation is required for exiting contact inhibition, oncogenesis, and adipogenesis (2012) (23)
Mextli Is a Novel Eukaryotic Translation Initiation Factor 4E-Binding Protein That Promotes Translation in Drosophila melanogaster (2013) (22)
X-ray studies of the messenger RNA 5' cap-binding protein (eIF4E) bound to 7-methyl-GDP. (1997) (22)
Association between LRRK2 and 4E-BP1 protein levels in normal and malignant cells. (2011) (22)
Prostate Cancer Progression (2010) (22)
The mTOR Targets 4E-BP1/2 Restrain Tumor Growth and Promote Hypoxia Tolerance in PTEN-driven Prostate Cancer (2018) (22)
Induction of CD4 expression and human immunodeficiency virus type 1 replication by mutants of the interferon-inducible protein kinase PKR (1997) (22)
Macrophage Inflammatory Protein-1α and Interferon-Inducible Protein 10 Inhibit Synergistically Induced Growth Factor Stimulation of MAP Kinase Activity and Suppress Phosphorylation of Eukaryotic Initiation Factor 4E and 4E Binding Protein 1 (1997) (22)
The intra-tumor heterogeneity of cell signaling factors in breast cancer: p4E-BP1 and peIF4E are diffusely expressed and are real potential targets (2014) (22)
A collection of caged compounds for probing roles of local translation in neurobiology. (2010) (22)
eIF4A inhibition circumvents uncontrolled DNA replication mediated by 4E-BP1 loss in pancreatic cancer. (2019) (21)
Characterization of rabbit reticulocyte factor(s) that stimulates the translation of mRNAs lacking 5'-terminal 7-methylguanosine. (1979) (21)
Constitutive Interferon Attenuates RIPK1/3-Mediated Cytokine Translation (2020) (21)
The ShcA adaptor activates AKT signaling to potentiate breast tumor angiogenesis by stimulating VEGF mRNA translation in a 4E-BP-dependent manner (2014) (21)
HGF-induced migration depends on the PI(3,4,5)P3-binding microexon-spliced variant of the Arf6 exchange factor cytohesin-1 (2018) (21)
Translational control of long-term synaptic plasticity and memory storage by eIF2alpha. (2006) (21)
Inhibitory properties of nucleic acid‐binding ligands on protein synthesis (2005) (21)
Translational control and autism-like behaviors (2013) (21)
Higher order structures of the 5'-proximal region decrease the efficiency of translation of the porcine pro-opiomelanocortin mRNA. (1988) (20)
Hepatic posttranscriptional network comprised of CCR4–NOT deadenylase and FGF21 maintains systemic metabolic homeostasis (2019) (20)
The Perks of Balancing Glucose (2001) (19)
The long unfinished march towards understanding microRNA-mediated repression (2015) (19)
A photo-induced reaction of chloramphenicol with E. coli ribosomes: covalent binding of the antibiotic and inactivation of peptidyl transferase. (1974) (19)
5' UTR of hepatitis A virus RNA: mutations in the 5'-most pyrimidine-rich tract reduce its ability to direct internal initiation of translation. (1995) (19)
Functional and direct interaction between the RNA binding protein HuD and active Akt1 (2011) (19)
A continuum of mRNP complexes in embryonic microRNA-mediated silencing (2016) (19)
Repair of Isoaspartate Formation Modulates the Interaction of Deamidated 4E-BP2 with mTORC1 in Brain* (2010) (19)
PABP Interacting Protein 2A (PAIP2A) Regulates Specific Key Proteins During Spermiogenesis in the Mouse1 (2012) (19)
Nuclear assortment of eIF4E coincides with shut-off of host protein synthesis upon poliovirus infection. (2010) (19)
Inhibiting the MNK1/2-eIF4E axis impairs melanoma phenotype switching and potentiates anti-tumor immune responses. (2021) (18)
Mapping of the gene for interferon‐inducible dsRNA‐dependent protein kinase to chromosome region 2p21‐22: A site of rearrangements in myeloproliferative disorders (1993) (18)
Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis (2018) (18)
Distinctive tRNA Repertoires in Proliferating versus Differentiating Cells (2014) (17)
Targeting mtor-dependent tumours with specific inhibitors: a model for personalized medicine based on molecular diagnoses (2009) (17)
Aminoacylation of Proteins: New Targets for the Old ARSenal. (2018) (17)
microRNA-mediated translation repression through GYF-1 and IFE-4 in C. elegans development (2021) (17)
A wheat germ cap-site factor functional in protein chain initiation. (1986) (16)
A bulge structure in HIV-1 TAR RNA is required for Tat binding and Tat-mediated trans-activation. (1990) (16)
A chemical genetic screen for mTOR pathway inhibitors based on 4E-BP-dependent nuclear accumulation of eIF4E. (2009) (16)
eIF-4E Phosphorylation and the Regulation of Protein Synthesis (1993) (16)
Deficiency in mTORC 1-controlled C / EBP beta-mRNA translation improves metabolic health in mice (2015) (16)
Antiviral Effects of Interferon-β are Enhanced in the Absence of the Translational Suppressor 4E-BP1 in Myocarditis Induced by Coxsackievirus B3 (2011) (16)
Mitochondrial Threonyl-tRNA Synthetase TARS2 Is Required for Threonine-Sensitive mTORC1 Activation. (2020) (16)
Complete Translation of the Hepatitis C Virus Genome In Vitro: Membranes Play a Critical Role in the Maturation of All Virus Proteins except for NS3 (2005) (16)
The eukaryotic translation initiation factor 4E is not modified during the course of vaccinia virus replication. (1992) (15)
Translational control by the poly(A) binding protein: A check for mRNA integrity (2006) (15)
Identification and characterization of hippuristanol-resistant mutants reveals eIF4A1 dependencies within mRNA 5′ leader regions (2020) (15)
Modulation of the mitogenic activity of eukaryotic translation initiation factor-4E by protein kinase C. (1991) (15)
Social propinquity in rodents as measured by tube cooccupancy differs between inbred and outbred genotypes (2017) (15)
The translational landscape of ground state pluripotency (2020) (14)
Assays for eukaryotic translation factors that bind mRNA. (1997) (14)
Contrasting mechanisms of regulating translation of specific Drosophila germline mRNAs at the level of 5'-cap structure binding. (2005) (14)
Protein Synthesis and Translational Control: A Historical Perspective. (2018) (14)
Impaired myelopoiesis in mice lacking the repressors of translation initiation, 4E‐BP1 and 4E‐BP2 (2009) (14)
Developmental regulation of translation by the 5' noncoding region of murine c-myc mRNA in Xenopus laevis. (1988) (14)
microRNA-induced translational control of antiviral immunity by the cap-binding protein 4EHP. (2021) (14)
Restricted initiation of protein synthesis on the potentially polycistronic Sindbis virus 42 S RNA. (1980) (14)
The multifaceted eukaryotic cap structure (2020) (14)
Construction of a fused LuxAB gene by site-directed mutagenesis. (1989) (13)
Insulin stimulates IGFBP-2 expression in 3T3-L1 adipocytes through the PI3K/mTOR pathway (2012) (13)
The Distribution of eIF4E-Family Members across Insecta (2012) (13)
Cocrystal Structure of the Messenger RNA 5' Cap-binding Protein (eIF4E) bound to 7-methylGpppG (2002) (13)
Probing the function of the eukaryotic 5'-cap structure using monoclonal antibodies to cap-binding proteins. (1982) (12)
Cancer genomics: the post-transcriptional era. (2013) (12)
Burn Out or Fade Away? (2010) (12)
Dynamic interaction of poly(A)-binding protein with the ribosome (2018) (12)
SARS-CoV-2 impairs interferon production via NSP2-induced repression of mRNA translation (2022) (12)
Coordinated transcriptional and translational control in metabolic homeostasis in flies. (2007) (11)
eIF4E S209 phosphorylation licenses myc- and stress-driven oncogenesis (2020) (11)
4E‐BP1 and 4E‐BP2 double knockout mice are protected from aging‐associated sarcopenia (2019) (11)
A highly efficient and robust in vitro translation system for expression of picornavirus and hepatitis C virus RNA genomes. (2007) (11)
4E-BP2/SH2B1/IRS2 Are Part of a Novel Feedback Loop That Controls β-Cell Mass (2016) (11)
Non-cooperative 4E-BP2 folding with exchange between eIF4E-binding and binding-incompatible states tunes cap-dependent translation inhibition (2020) (11)
Aster‐C coordinates with COP I vesicles to regulate lysosomal trafficking and activation of mTORC1 (2020) (11)
Mapping of 23-S rRNA at the ribosomal peptidyl-transferase center by photo-affinity labeling. (1977) (10)
Unorthodox mechanisms to initiate translation open novel paths for gene expression. (2020) (10)
Eukaryotic initiation factor 4F-sidestepping resistance mechanisms arising from expression heterogeneity. (2018) (10)
Translation and cancer. (2015) (10)
Design and preparation of affinity columns for the purification of eukaryotic messenger ribonucleic acid cap binding protein. (1981) (9)
Poliovirus MutantThatDoesNotSelectively Inhibit HostCell Protein Synthesis (1985) (9)
Expression of Reovirus Type 3 (Dearing) σ1 and σs Polypeptides in Escherichia coli (1987) (9)
4E-BP–Dependent Translational Control of Irf8 Mediates Adipose Tissue Macrophage Inflammatory Response (2020) (9)
Muscle metabolic alterations induced by genetic ablation of 4E-BP1 and 4E-BP2 in response to diet-induced obesity. (2017) (9)
Polysome Profiling Analysis (2013) (9)
Identification of a protein that binds specifically to RNA from the first exon of c-myc. (1989) (9)
Translational Control Mechanisms in Synaptic Plasticity and Memory (2008) (8)
V-ATPase-associated prorenin receptor is upregulated in prostate cancer after PTEN loss (2019) (8)
4E-BP2–dependent translation in parvalbumin neurons controls epileptic seizure threshold (2021) (7)
Removing 4E-BP Enables Synapses to Refine without Postsynaptic Activity. (2018) (7)
Protein synthesis. The perks of balancing glucose. (2001) (7)
Gimme phospho-serine five! Capping enzyme guanylyltransferase recognition of the RNA polymerase II CTD. (2011) (7)
R mRNA surveillance by a yeast antiviral system . by a double-stranded RNA virus and poly ( A )-Decoying the cap-mRNA degradation system (1995) (7)
mRNA translation is a therapeutic vulnerability necessary for bladder epithelial transformation (2021) (7)
Rotational symmetry in ribonucleotide strand requirements for binding of HIV-1 Tat protein to TAR RNA (1993) (7)
Dysregulated translational control in brain disorders: from genes to behavior. (2020) (7)
P2.206 EIF4G1 mutations in familial parkinsonism (2009) (7)
Problems with Co-Funding in Canada (2005) (7)
An efficient system for let-7 microRNA and GW182 protein-mediated deadenylation in vitro. (2011) (6)
Identification of the 80-kDa protein that crosslinks to the cap structure of eukaryotic mRNAs as initiation factor eIF-4B. (1988) (6)
Association of cap binding protein‐related polypeptides with cytoplasmic RNP particles of chick embryonic muscle (1982) (6)
Assessing eukaryotic initiation factor 4F subunit essentiality by CRISPR-induced gene ablation in the mouse (2021) (6)
The eIF4E homolog 4EHP (eIF4E2) regulates hippocampal long-term depression and impacts social behavior (2020) (6)
Eukaryotic mRNA cap binding protein : Purification by affinity chromatography on Sepharose-coupled m 7 GDP ( 7-methylguanosine / eukaryotic initiation factors / protein synthesis ) (6)
Structural Dynamics of the GW182 Silencing Domain Including its RNA Recognition motif (RRM) Revealed by Hydrogen-Deuterium Exchange Mass Spectrometry (2017) (6)
Rheb1-Independent Activation of mTORC1 in Mammary Tumors Occurs through Activating Mutations in mTOR. (2020) (6)
Photo-affinity labeling of 23 S rRNA by an analog of fMet-tRNAMet-f. (1976) (6)
Lab-On-A-Chip for the Development of Pro-/Anti-Angiogenic Nanomedicines to Treat Brain Diseases (2019) (6)
Chromosomal assignment of one of the mammalian translation initiation factor eIF-4E genes. (1991) (6)
Elevated V–ATPase Activity Following PTEN Loss Is Required for Enhanced Oncogenic Signaling in Breast Cancer (2020) (5)
Membrane-dependent relief of translation elongation arrest on pseudouridine- and N1-methyl-pseudouridine-modified mRNAs (2021) (5)
Role of Translational Attenuation in Inherited Retinal Degeneration (2019) (5)
Circular dichroism and fluorescence studies on five mutant forms of protein synthesis initiation factor eIF‐4E, from the yeast Saccharomyces cerevisiae (1989) (5)
Protein Synthesis and Translational Control (2012) (5)
The Eukaroyotic mRNA Cap Binding Protein (eIF-4E): Phosphorylation and Regulation of Cell Growth (1990) (5)
Crystallization and preliminary X-ray diffraction analysis of the MIF4G domain of DAP5. (2010) (4)
Internal Ribosome Entry Site-Mediated Translation (2016) (4)
High-risk human papillomavirus-18 uses an mRNA sequence to synthesize oncoprotein E6 in tumors (2021) (4)
eIF4E and Its Binding Proteins (2014) (4)
Diverse cap-binding properties of Drosophila eIF4E isoforms. (2016) (4)
RNA-protein interactions in regulation of picornavirus RNA translation (1996) (4)
Towards development of an in vitro translation test for poliovirus neurovirulence. (1993) (4)
Preferential stimulation of rabbit alpha globin mRNA translation by a cap-binding protein complex. (1984) (4)
Initiation factors elF4A and C1 from wheat germ and the formation of mRNA · ribosome complexes (1985) (4)
Lesch-Nyhan disease causes impaired energy metabolism and reduced developmental potential in midbrain dopaminergic cells (2021) (4)
The Effect of Poliovirus Proteinase 2 APr 0 Expression on Cellular Metabolism (2001) (3)
mRNA Translation in Diabetic Nephropathy (2006) (3)
The Leader of Human Immunodeﬁciency Virus Type 1 Genomic RNA Harbors an Internal Ribosome Entry Segment That Is Active during the G 2 /M Phase of the Cell Cycle (2003) (3)
Translation inSaccharomyces cerevisiae: Initiation Factor 4E-Dependent Cell-Free System (1989) (3)
Transcriptional induction of 4E-BP3 prolongs translation repression (2016) (3)
Nociceptor translational profiling reveals the RagA-mTORC1 network as a critical generator of neuropathic pain (2018) (3)
Macrophage inflammatory protein-1alpha and interferon-inducible protein 10 inhibit synergistically induced growth factor stimulation of MAP kinase activity and suppress phosphorylation of eukaryotic initiation factor 4E and 4E binding protein 1. (1997) (3)
Protein Synthesis Initiation in Eukaryotes: IRES‐mediated Internal Initiation (2015) (3)
Wakefulness/sleep architecture and electroencephalographic activity in mice lacking the translational repressor 4E-BP1 or 4E-BP2. (2019) (3)
Studies on the Mechanism of Internal Initiation of Translation on Poliovirus RNA (1993) (3)
On board. (2003) (3)
BAD regulates mammary gland morphogenesis by 4E-BP1-mediated control of localized translation in mouse and human models (2021) (3)
TPL2 kinase expression is regulated by the p38γ/p38δ-dependent association of aconitase-1 with TPL2 mRNA (2022) (3)
Crystallization and preliminary X-ray diffraction analysis of the middle domain of Paip1. (2009) (2)
Abstract LB-302: eIF4E phosphorylation is Mnk-dependent but does not require assembly of the eIF4F translation initiation complex (2014) (2)
UBR4/POE facilitates secretory trafficking to maintain circadian clock synchrony (2022) (2)
The amino acid sensor GCN2 controls red blood cell clearance and iron metabolism through regulation of liver macrophages (2022) (2)
Protein Synthesis in Eukaryotes: IRES‐mediated Internal Initiation (2006) (2)
4E-BP2-dependent translation in cerebellar Purkinje cells controls spatial memory but not autism-like behaviors. (2021) (2)
Association of an Mr 50,000 cap binding protein with the cytoskeleton in BHK cells. (1982) (2)
Translational Control Through the EIF4E Binding Proteins in the Brain (2018) (2)
MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice (Journal of Clinical Investigation (2010) 120, 8, (2805-2816) DOI: 10.1172/JCI43008) (2010) (2)
Protein synthesis and translational control : a subject collection from Cold Spring Harbor perspectives in biology (2012) (2)
Initiation of protein synthesis. (2006) (2)
Author response: Pharmacological brake-release of mRNA translation enhances cognitive memory (2013) (2)
PABP Interacting Protein 2 (Paip2) Is a Major Translational Regulator Involved in the Maturation of Male Germ Cells and Male Fertility. (2009) (2)
Myeloid Cells B To Drive RANTES Production by κ , JNK, and NF- α IL-15 Can Signal via IL-15R (2012) (2)
A continuum of mRNP complexes in embryonic microRNA-mediated silencing. (2016) (2)
Abstract 5349: Vesicular stomatitis virus oncolysis is potentiated by impairing mTORC1-dependent type-I IFN production (2010) (2)
Initiation factors eIF4A and C1 from wheat germ and the formation of mRNA X ribosome complexes. (1985) (2)
Abstract PR03: NRF2 promotes tumor maintenance by modulating mRNA translation in pancreatic cancer (2017) (2)
Murine p53 inhibits the function but not the formation of SV40 T antigen hexamers and stimulates T antigen RNA helicase activity (2006) (2)
hydrolysis.required for RNA binding and ATP helicase eukaryotic translation initiation factor The HRIGRXXR region of the DEAD box RNA (2013) (2)
Research on mRNA translation into protein. (1997) (1)
The translation initiation factor eIF-4B contains an RNA-binding region that is distinct and independent from its ribonucleoprotein consensus sequence (1994) (1)
5′-TERMINAL CAPS IN EUKARYOTIC mRNAS (1979) (1)
Translational Control of Synaptic Plasticity and Memory (2012) (1)
TheCoatProtein oftheYeastDouble-Stranded RNA Virus L-AAttaches Covalently totheCapStructure of Eukaryotic mRNA (1992) (1)
Involvement of epiregulin and epidermal growth factor receptor in pain (2017) (1)
Evolution of naturally arising SARS-CoV-2 defective interfering particles (2022) (1)
10 Translation Initiation and Cell Growth Control (2004) (1)
CHAPTER 322 – Signaling Pathways That Mediate Translational Control of Ribosome Recruitment to mRNA (2003) (1)
PWE-021 Mtorc1 Mediated Translational Elongation Is Limiting For Intestinal Tumour Initiation And Growth (2014) (1)
Actions of Insulin As a Survival and Growth Factor: Akt, mTOR, and Regulation of Translation (2011) (1)
Association between LRRK 2 and 4 EBP 1 protein levels in normal and malignant cells (2011) (1)
Aaron Shatkin (1934–2012) (2012) (1)
A homologous series of photoreactive peptidyl-tRNAs for probing the ribosomal peptidyltransferase center. (1977) (1)
Downstream of mTOR: Translational Control of Cancer (2009) (1)
Mechanism of action of miRNA (2012) (1)
Alexander Spirin (1931–2020): A visionary scientist, a teacher, a colleague, a friend (2021) (1)
4E‐BPs at the crossroads of oncogenic MAPK and AKT signaling (2010) (1)
The rate of protein synthesis in hematopoietic stem cells is limited partly by 4 E-BPs Citation Signer (2016) (1)
Pancreatic Neuroendocrine Tumors (2014) (1)
Key-1 Translational control of innate immunity via IRF-7 (2008) (0)
Demonstration InVitro thatEucaryotic Initiation Factor 3IsActive butthat a Cap-Binding Protein ComplexIsInactive inPoliovirus- Infected HeLaCells (1984) (0)
Alternative splicing facilitates internal binding of ribosomes to the ornithine decarboxylase mRNA in pancreatic tumoral cells (2008) (0)
Crystal structure of human CNOT1 MIF4G domain in complex with a TTP peptide (2013) (0)
p38γ and p38δ modulate innate immune response by regulating MEF2D activation (2022) (0)
PSEUDO-HALF-KNOT RNA FORMATION BY HYBRIDIZATION OF ANTISENSE OLIGONUCLEOTIDES TO TARGET RNA ’ S SECONDARY STRUCTURE PSEUDO-HALBKNOTEN AUSBILDENDE RNA (2004) (0)
IDENTIFICATION OF POTENTIAL ANTI‐ONCOGENIC PROPERTIES OF elF‐4E BINDING PROTEINS 1 AND 2 (1996) (0)
Granzyme B inhibits translation of viral proteins and viral replication through proteolytic cleavage of the eukaryotic initiation factor 4 gamma 3 (154.35) (2011) (0)
Evidence for a Tumor Promoting Effect of High Fat Diet in the Absence of Hyperinsulinemia in HER2/Neu Mammary Carcinogenesis (2008) (0)
Correction: A role for the eIF4E-binding protein 4E-T in P-body formation and mRNA decay (2005) (0)
A study of mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1. Morita et al. (2017) (0)
PS2-77 IFN-mediated regulation of protein translation and its role in an antiviral immune response (2009) (0)
Linking depression, mRNA translation, and serotonin (2021) (0)
Metformin mediated AMPK activation inhibits translation initiation in breast cancer cells (2007) (0)
Preface/Front Matter (1971) (0)
Abstract 321: Deletion Of The Translational Repressors Eukaryotic Translation Initiation Factor 4e Binding Proteins 1 And 2 Protects Against Pressure Overload Induced Heart Failure (2013) (0)
Explorer G 3 BP 1 promotes stress-induced RNA granule interactions to preserve polyadenylated mRNA (2017) (0)
Abstract CT521: Phase 1b trial of the MNK1/2 inhibitor tomivosertib combined with paclitaxel in patients with metastatic breast cancer (2022) (0)
- Claude Activities 4 E-Binding Protein 1 and p 70 S 6 Kinase Translation Initiation Factor 4 E Control of Translational Homeostasis : Eukaryotic (1999) (0)
Inhibit Synergistically Induced Growth Factor Stimulation of MAP Kinase Activity and Suppress Phosphorylation of Eukaryotic Initiation Factor 4E and 4E Binding Protein 1 (1997) (0)
Novel Cytoplasmic Cap Binding Proteins in Yeast (1993) (0)
COCRYSTAL STRUCTURE OF EIF4E/4E-BP1 PEPTIDE (2000) (0)
miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4–NOT (2012) (0)
Differentiation Initiation , During Human Myeloid Cell 4 EBP 2 , Two Repressors of Translation Differential Regulation of 4 EBP 1 and and (1999) (0)
Symposium S7: Regulation of Translation in Synaptic Plasticity & Memory (2004) (0)
Intermolecular Interactions of Proteins Involved in the Control of Gene Expression (1999) (0)
Decision letter: An mRNA-binding channel in the ES6S region of the translation 48S-PIC promotes RNA unwinding and scanning (2019) (0)
Inhibiteurs de la replication du vih a base de peptides (1991) (0)
The role of eukaryotic translation initation factor 4E (eIF4E)regulation during viral infection (2010) (0)
213 Cell cycle and translational requirements for VSV oncolysis in primary CD4+ T-Lymphocytes (2008) (0)
Crystal structure of MID domain from hAGO2 (2010) (0)
Proceedings: Study of the peptidyl-transferase center of Escherichia coli ribosomes by photo-affinity labeling. (1975) (0)
Abstract 4329: Lipid droplets and associated proteins in hepatocellular carcinoma tumour cells (2014) (0)
NRF 2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer Graphical (0)
Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E (2018) (0)
Inhibition of eIF4E Phosphorylation Regulates Plaque Composition Without Affecting Atherosclerosis Development (2018) (0)
Translational regulation of cancer metabolism by the mTOR signaling pathway (2016) (0)
A threonyl-tRNA synthetase-mediated translation initiation machinery (2019) (0)
p 38 mitogen-activated protein kinase ( MAPK ) / MAPK-activated protein kinase 2 ( MK 2 ) signaling cascade in oligodendrocyte differentiation (2009) (0)
The MNK1/2-eIF4E axis drives melanoma plasticity, progression, and resistance to immunotherapy (2020) (0)
Control Of Translation From The mRNA 3′ End (2007) (0)
5′-CAPPING AND EUKARYOTIC mRNA FUNCTION (1979) (0)
Cell-type-specific translational control of spatial working memory by the cap-binding protein 4EHP (2023) (0)
in cisplatin sensitivity (2005) (0)
PABP Interacting Protein 2 (Paip2) Regulates the Translation of Key Proteins Involved inSpermiogenesis. (2010) (0)
SARS-CoV-2 protein NSP2 enhances microRNA-mediated translational repression (2023) (0)
Editorial Board (2009) (0)
Capped mRNAswithReduced Secondary Structure Can Function inExtracts fromPoliovirus-Infec ted Cells (1982) (0)
Package 'anota' (0)
Peptidase inhibitors of the hi-virusreplikation (1993) (0)
Abstract 2417: eIF4E phosphorylation licenses Myc-driven metabolic and stress reprogramming (2018) (0)
Translational control of DNA replication by 4E-BP1 in pancreatic cancer (2018) (0)
Loss of 4E-BP1-mediated translational control favors DNA replication in pancreatic cancer. (2017) (0)
Crystal structure of Arabidopsis AGO1 in complex with AMP (2012) (0)
Title: Nociceptor translational profiling reveals the RagA-mTORC1 network as a critical generator of neuropathic pain Short Title: Nociceptor translational profiling (2018) (0)
Translational regulation of exocrine cell function and survival by ATF4-dependent expression of 4E-BP1 (2015) (0)
Messenger RNA Translation Defects in Neurodegenerative Diseases. (2023) (0)
Abstract IA09: Translational control of the tumor microenvironment (2017) (0)
MIF4G domain of DAP5 (2013) (0)
Single-Molecule Studies of the Effects of Small Compounds on the Activity of Translation Initiation Factor eIF4A (2011) (0)
Attenuation of translational repression rescues memory impairment in Alzheimer`s disease mice (2022) (0)
Signaling Pathways that Mediate Translational Control of Ribosome Recruitment to mRNA (2010) (0)
Abstract PR04: Nrf2 promotes mRNA translation in pancreatic cancer (2016) (0)
Immunity to protozoan parasite infection (WS-002) Chairpersons: Hiroki Yoshida, Alioune Dieye (2010) (0)
Non-cooperative 4E-BP2 folding with exchange between eIF4E-binding and binding-incompatible states tunes cap-dependent translation inhibition (2020) (0)
CAP BINDING PROTEIN RELATED POLYPEPTIDES IN CYTOPLASMIC RIBONUCLEOPROTEIN PARTICLES OF CHICK EMBRYONIC MUSCLE (1982) (0)
Protein Synthesis in Eukaryotes: Internal Initiation (2001) (0)
Author response: Translational control of nociception via 4E-binding protein 1 (2015) (0)
Translational Control of Autism and Fragile-X Syndrome (2014) (0)
193 IFN-mediated inactivation of the 4E-BP1 repressor of mRNA translation influences an antiviral response (2008) (0)
Crystal structure of MID domain from hAGO2 in complex with AMP (2010) (0)
Crystal structure of Arabidopsis thaliana AGO1 MID domain in complex with CMP (2012) (0)
Structural dynamics of proteins involved in miRNA mediated gene silencing (2016) (0)
, melanogaster Promotes Translation in Drosophila Initiation Factor 4 E-Binding Protein That Mextli Is a Novel Eukaryotic Translation (2013) (0)
Nucleic Acids Research MATERIALS AND METHODS Preparation of RNAs . PVX RNA (2005) (0)
Retraction. Macrophage inflammatory protein-1alpha and interferon-inducible protein 10 inhibit synergistically induced growth factor stimulation of MAP kinase activity and suppress phosphorylation of eukaryotic initiation factor 4E and 4E binding protein 1. (2006) (0)
Therapeutic Discovery Modulation of 4 EBP 1 Function as a Critical Determinant of Enzastaurin-Induced Apoptosis (2010) (0)
, M multiplication . type 1 gene expression and virus activation of human immunodeficiency virus block Tat-tumor necrosis factor synergistic Transdominant mutants of I kappa B alpha (1996) (0)
, R receptor substrate 1-deficient mice . muscles and livers of insulin-resistant , insulin Insulin signalling and insulin actions in the (1996) (0)
Expression of reovirus type 3 (Dearing) sigma 1 and sigma s polypeptides in Escherichia coli. (1987) (0)
Graphical contents list (2010) (0)
Peptidic inhibitors of HIV replication (1991) (0)
Protein Repressor Paip2 with Poly(A) Binding Dual Interactions of the Translational (2014) (0)
Abstracts of papers presented at the 1989 Meeting on Translational Control, September 13-September 17, 1989 (1989) (0)
Crystal structure of Arabidopsis thaliana AGO2 MID domain (2012) (0)
Analogs of chloramphenicol and their application to labeling ribosomes. (1977) (0)
NMR structure of Phosphorylated 4E-BP2 (2015) (0)
THE mRNA CAP-BINDING PROTEIN EIF4E: WHY DO MANY VIRUSES DISLIKE THIS FACTOR? (2019) (0)
Involvement of the AU‐Rich Elements in the Translational Control of the Human IL‐3 mRNA. (2006) (0)
Nahum Sonenberg and In Vitro Virus Internal Ribosome Entry Site In Vivo Function of the Poliovirus and Hepatitis C La Autoantigen Is Necessary for Optimal (2004) (0)
eIF4E interacts with a shuttling protein (1999) (0)
Cap-Binding-Protein Related Polypeptides in Cytoplasmic RNP Particles of Chick Embryonic Mscle (1982) (0)
EIF4E/EIF4G PEPTIDE/7-METHYL-GDP (2000) (0)
Microfluidic Wound-Healing Assay for ECM and Microenvironment Properties on Microglia BV2 Cells Migration (2023) (0)
Functional and Structural Characteristics of Eucaryotic mRNA Cap-Binding-Protein Complex (1983) (0)
Loss of 4E-BP Converts Cerebellar Long-Term Depression to Long-Term Potentiation (2021) (0)
Inhibitors of HIV replication peptide-based virus. (1991) (0)
Translational Control by 4E-BP1/2 Suppressor Proteins Regulates Mitochondrial Biosynthesis and Function during CD8+ T Cell Proliferation (2022) (0)
Translational control of tumor immune escape via the eIF4F–STAT1–PD-L1 axis in melanoma (2018) (0)
ANalysis Of Translational Activity ( anota ) (2013) (0)
Profile of Michael N. Hall, 2017 Albert Lasker Basic Medical Research Awardee: Target of rapamycin, cell growth, and translational control (2017) (0)
Role of La in internal initiation (1995) (0)
Cover Image (2021) (0)
RNA Helicase Activity in Translation Initiation in Eukaryotes (1993) (0)
MNK/eIF4E Ser209 Deletion Confers Protection in Murine Bleomycin Induced Lung Fibrosis Model (2020) (0)
ATP-Mi’+ INDEPENDENT CROSS-LINKING OF CAP BINDING PROTEINS TO m71-CAPPED INOSINE- SUBSTITUTED REOVIRUS mRNA* (2001) (0)
Crystal structure of the PABC-TNRC6C complex (2010) (0)
CS08-2. Ifn regulation of metabolism contributes to an antiviral response (2011) (0)
Therapeutic targeting of eukaryotic initiation factor (eIF) 4E. (2023) (0)
Post-transcriptional regulation via the mRNA poly(A) tail during spermatogenesis (2017) (0)
Crystal structure of Arabidopsis thaliana AGO5 MID domain (2012) (0)
melanogasterTranslation in Drosophila Initiation Factor 4E-Binding Protein That Mextli Is a Novel Eukaryotic Translation (2013) (0)
Crystal Structure of Arabidopsis thaliana AGO1 MID domain (2012) (0)
Abstract B06: Translational control of mitochondria through mTORC1/4E-BP signaling pathway (2017) (0)
Correction: Role of 3′UTRs in the Translation of mRNAs Regulated by Oncogenic eIF4E—A Computational Inference (2009) (0)
Nucleic Acids Research (2011) (0)
Decision letter: GTPBP1 resolves paused ribosomes to maintain neuronal homeostasis (2020) (0)
Excitatory neuron-specific suppression of the integrated stress response pathway contributes to autism-related phenotypes in a mouse model of fragile X syndrome (2023) (0)
TRANSLATION INITIATION FACTOR EIF4E IN COMPLEX WITH M7GDP, NMR, 20 STRUCTURES (1998) (0)
RNA chiropractics (1998) (0)
MAPKAP Kinase-2 phosphorylation of PABPC1 controls its interaction with 14-3-3 proteins after DNA damage: A combined kinase and protein array approach (2023) (0)
The translational landscape of ground state pluripotency (2020) (0)
X-RAY CRYSTAL STRUCTURE OF THE POLY(A)-BINDING PROTEIN IN COMPLEX WITH POLYADENYLATE RNA (1999) (0)
Eleven Thematic Meetings within the National Meeting Every Day (2003) (0)
423 POSTER Metformin is an AMP-kinase dependent growth inhibitor for breast cancer cells (2006) (0)
CAP FUNCTION AND REGULATION OF TRANSLATION DURING POLIOVIRUS INFECTION (1982) (0)
The low rate of protein synthesis in hematopoietic stem cells is determined partly by hypophosphorylation of 4E-BPS (2016) (0)
Translational control of memory CD8 T cell differentiation (LYM4P.752) (2014) (0)
Translation deregulation in human disease (2018) (0)
A POLYPEPTIDE IN INITIATION FACTOR PREPARATIONS THAT RECOGNIZES THE 5′-TERMINAL CAP IN EUKARYOTIC mRNA (1979) (0)
MIDDLE DOMAIN OF HUMAN EIF4GII (2001) (0)
Decision letter: EDF1 coordinates cellular responses to ribosome collisions (2020) (0)
Study of Incinerated Nanodiamonds and Their Effect on Microglial Cells (2020) (0)
Abstract IA7: Translational control of cancer via eIF4E/4E-BPs (2013) (0)
Dynamic interaction of poly(A)-binding protein with the ribosome (2018) (0)
Role of the MAPK and mTORC1 Pathways mRNA Translation and Energy Metabolism in Cancer: The (2011) (0)
mTOR Controls Mitochond rial Dynamics and Cell Survival via MTFP 1 Graphical Abstract Highlights (2017) (0)
Author response: eIF4E S209 phosphorylation licenses myc- and stress-driven oncogenesis (2020) (0)
Some correlations between ribosomal proteins and ribosomal activities. (1974) (0)
Corrections (2008) (0)
Edinburgh Research Explorer Control of embryonic stem cells self-renewal and differentiation via coordinated splicing and translation of YY2 (2016) (0)
Correction (2005) (0)
Richard Jackson (1940-2020) - A towering presence in translation. (2021) (0)
C-terminal portion of human eIF4GI (2005) (0)
Loss of 4E-BP converts cerebellar long-term depression to long-term potentiation. (2022) (0)

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