Nancy Papalopulu
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Professor of Developmental Neuroscience
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Why Is Nancy Papalopulu Influential?
(Suggest an Edit or Addition)According to Wikipedia, Athanasia Papalopulu is a Wellcome Trust senior research fellow and Professor of Developmental Neuroscience in the School of Biological Sciences, University of Manchester. Education After completing her undergraduate degree in Pharmacy at the Aristotle University of Thessaloniki, Greece, Nancy Papalopulu moved to London in 1986 to do a PhD at the National Institute for Medical Research, where she became one of Robb Krumlauf's first graduate students. There she studied the role of Hox genes in patterning the nervous system. She completed her PhD in 1991.
Nancy Papalopulu's Published Works
Published Works
- The murine and Drosophila homeobox gene complexes have common features of organization and expression (1989) (975)
- Downregulation of Par3 and aPKC function directs cells towards the ICM in the preimplantation mouse embryo (2005) (251)
- Retinoic acid causes abnormal development and segmental patterning of the anterior hindbrain in Xenopus embryos. (1991) (244)
- An essential role for retinoid signaling in anteroposterior neural patterning. (1997) (244)
- microRNA-9 regulates axon extension and branching by targeting Map1b in mouse cortical neurons (2012) (241)
- Techniques and probes for the study of Xenopus tropicalis development (2002) (228)
- Xenopus Distal-less related homeobox genes are expressed in the developing forebrain and are induced by planar signals. (1993) (227)
- Expression of Pax-3 in the lateral neural plate is dependent on a Wnt-mediated signal from posterior nonaxial mesoderm. (1999) (205)
- Expression of Pax-3 is initiated in the early neural plate by posteriorizing signals produced by the organizer and by posterior non-axial mesoderm. (1997) (191)
- MicroRNA-9 Modulates Hes1 Ultradian Oscillations by Forming a Double-Negative Feedback Loop (2012) (182)
- XBF-1, a winged helix transcription factor with dual activity, has a role in positioning neurogenesis in Xenopus competent ectoderm. (1998) (181)
- Xiro3 encodes a Xenopus homolog of the Drosophila Iroquois genes and functions in neural specification (1998) (180)
- A posteriorising factor, retinoic acid, reveals that anteroposterior patterning controls the timing of neuronal differentiation in Xenopus neuroectoderm. (1996) (167)
- MicroRNA-9 Reveals Regional Diversity of Neural Progenitors along the Anterior-Posterior Axis (2011) (157)
- Integration of telencephalic Wnt and hedgehog signaling center activities by Foxg1. (2009) (152)
- aPKC, Crumbs3 and Lgl2 control apicobasal polarity in early vertebrate development (2005) (140)
- Characterization of a murine homeo box gene, Hox-2.6, related to the Drosophila Deformed gene. (1988) (138)
- Distinct effects of XBF-1 in regulating the cell cycle inhibitor p27(XIC1) and imparting a neural fate. (2000) (137)
- tinman, a Drosophila homeobox gene required for heart and visceral mesoderm specification, may be represented by a family of genes in vertebrates: XNkx-2.3, a second vertebrate homologue of tinman. (1995) (134)
- Analysis of the murine Hox‐2.7 gene: conserved alternative transcripts with differential distributions in the nervous system and the potential for shared regulatory regions. (1992) (127)
- The expression of murine Hox-2 genes is dependent on the differentiation pathway and displays a collinear sensitivity to retinoic acid in F9 cells and Xenopus embryos. (1991) (127)
- Defining a large set of full-length clones from a Xenopus tropicalis EST project. (2004) (125)
- Oriented cell divisions asymmetrically segregate aPKC and generate cell fate diversity in the early Xenopus embryo (2003) (124)
- A Xenopus gene, Xbr-1, defines a novel class of homeobox genes and is expressed in the dorsal ciliary margin of the eye. (1996) (111)
- The neural progenitor-specifying activity of FoxG1 is antagonistically regulated by CKI and FGF (2007) (100)
- Intrinsic differences between the superficial and deep layers of the Xenopus ectoderm control primary neuronal differentiation. (2002) (91)
- Transgenic Xenopus embryos reveal that anterior neural development requires continued suppression of BMP signaling after gastrulation. (2001) (85)
- FGF-8 stimulates neuronal differentiation through FGFR-4a and interferes with mesoderm induction in Xenopus embryos (2000) (83)
- Embryonic frog epidermis: a model for the study of cell-cell interactions in the development of mucociliary disease (2011) (82)
- A secretory cell type develops alongside multiciliated cells, ionocytes and goblet cells, and provides a protective, anti-infective function in the frog embryonic mucociliary epidermis (2014) (76)
- Depletion of the cell-cycle inhibitor p27Xic1 impairs neuronal differentiation and increases the number of ElrC+ progenitor cells in Xenopus tropicalis (2003) (73)
- FoxG1 and TLE2 act cooperatively to regulate ventral telencephalon formation (2010) (72)
- Temporal and spatial expression of FGF ligands and receptors during Xenopus development (2009) (68)
- Atypical protein kinase C couples cell sorting with primitive endoderm maturation in the mouse blastocyst (2013) (68)
- Spindle Position in Symmetric Cell Divisions during Epiboly Is Controlled by Opposing and Dynamic Apicobasal Forces (2012) (67)
- pTransgenesis: a cross-species, modular transgenesis resource (2011) (61)
- microRNA input into a neural ultradian oscillator controls emergence and timing of alternative cell states (2014) (60)
- Pilot morpholino screen in Xenopus tropicalis identifies a novel gene involved in head development (2004) (56)
- The oncogenic potential of the high mobility group box protein Sox3. (2000) (50)
- The apicobasal polarity kinase aPKC functions as a nuclear determinant and regulates cell proliferation and fate during Xenopus primary neurogenesis (2009) (50)
- Grainyhead-like 3, a transcription factor identified in a microarray screen, promotes the specification of the superficial layer of the embryonic epidermis (2006) (49)
- Rab32 Regulates Melanosome Transport in Xenopus Melanophores by Protein Kinase A Recruitment (2007) (46)
- A default mechanism of spindle orientation based on cell shape is sufficient to generate cell fate diversity in polarised Xenopus blastomeres (2006) (45)
- A yeast artificial chromosome containing the mouse homeobox cluster Hox-2. (1990) (40)
- Stochasticity in the miR-9/Hes1 oscillatory network can account for clonal heterogeneity in the timing of differentiation (2016) (39)
- A Xenopus tropicalis oligonucleotide microarray works across species using RNA from Xenopus laevis (2005) (38)
- Characterisation of a new regulator of BDNF signalling, Sprouty3, involved in axonal morphogenesis in vivo (2010) (37)
- Inositol kinase and its product accelerate wound healing by modulating calcium levels, Rho GTPases, and F-actin assembly (2013) (36)
- Quantitative single-cell live imaging links HES5 dynamics with cell-state and fate in murine neurogenesis (2018) (34)
- Dynein light intermediate chains maintain spindle bipolarity by functioning in centriole cohesion (2014) (33)
- Spatiotemporal lipid profiling during early embryo development of Xenopus laevis using dynamic ToF-SIMS imaging (2014) (33)
- Molecular components of the endoderm specification pathway in Xenopus tropicalis (2003) (32)
- Identification of novel genes affecting mesoderm formation and morphogenesis through an enhanced large scale functional screen in Xenopus (2005) (32)
- Expression cloning screening of a unique and full-length set of cDNA clones is an efficient method for identifying genes involved in Xenopus neurogenesis (2005) (31)
- Identifying stochastic oscillations in single-cell live imaging time series using Gaussian processes (2016) (26)
- Analysis of neural progenitors from embryogenesis to juvenile adult in Xenopus laevis reveals biphasic neurogenesis and continuous lengthening of the cell cycle (2015) (24)
- A dominant-negative form of the E3 ubiquitin ligase Cullin-1 disrupts the correct allocation of cell fate in the neural crest lineage (2006) (23)
- aPKC Phosphorylates p27Xic1, Providing a Mechanistic Link between Apicobasal Polarity and Cell-Cycle Control (2014) (22)
- Dynamic properties of noise and Her6 levels are optimized by miR‐9, allowing the decoding of the Her6 oscillator (2020) (18)
- Multicolor fluorescent in situ mRNA hybridization (FISH) on whole mounts and sections. (2012) (17)
- Evading the annotation bottleneck: using sequence similarity to search non-sequence gene data (2008) (14)
- Regionalization of the forebrain from neural plate to neural tube. (1995) (13)
- Hox-2 homeobox genes and retinoic acid: potential roles in patterning the vertebrate nervous system (1990) (13)
- Dynamical gene regulatory networks are tuned by transcriptional autoregulation with microRNA feedback (2020) (12)
- Induction and patterning of the neural plate (1992) (12)
- Apicobasal polarity and cell proliferation during development. (2012) (9)
- Molecular genetics of neurulation. (2007) (9)
- Retinoic acid and the Xenopus hindbrain (1991) (9)
- HES1 protein oscillations are necessary for neural stem cells to exit from quiescence (2021) (9)
- A bromodeoxyuridine (BrdU) based protocol for characterizing proliferating progenitors in Xenopus embryos. (2012) (8)
- A dynamic, spatially periodic, micro‐pattern of HES5 underlies neurogenesis in the mouse spinal cord (2021) (7)
- Antibody development and use in chromogenic and fluorescent immunostaining. (2012) (7)
- Expression of Pax-3, a marker for dorsal and posterior neural tube, is initiated by posteriorizing signals produced by the organizer and by non-axial mesoderm (1997) (6)
- Methods to analyze microRNA expression and function during Xenopus development. (2012) (5)
- Differential phase register of Hes1 oscillations with mitoses underlies cell-cycle heterogeneity in ER+ breast cancer cells (2021) (5)
- Structure, expression and evolutionary relationships of murine homeobox genes in the Hox 2 cluster (1989) (4)
- Quantitative, real-time, single cell analysis in tissue reveals expression dynamics of neurogenesis (2018) (4)
- A dynamic, spatially periodic, micro-pattern of HES5 underlies neurogenesis in the mouse spinal cord (2020) (4)
- Inferring kinetic parameters of oscillatory gene regulation from single cell time-series data (2021) (3)
- Hox genes: a molecular code for patterning regional diversity in the nervous system and branchial structures. (1993) (3)
- Following the fate of neural progenitors by homotopic/homochronic grafts in Xenopus embryos. (2012) (1)
- Dynamic switching of lateral inhibition spatial patterns (2022) (1)
- Timing of neurogenesis through sequential accumulation of miR-9 due to additive expression of multiple alleles (2022) (1)
- OscoNet: inferring oscillatory gene networks (2019) (1)
- Hox-2: Gene regulation and segmental patterning in the vertebrate head (1991) (1)
- 16-P027 The role of ionocytes in Xenopus epidermal development (2009) (0)
- Bilateral Feedback in Oscillator Model Is Required to Explain the Coupling Dynamics of Hes1 with the Cell Cycle (2022) (0)
- 21-P020 The apical–basal polarity kinase aPKC functions as a nuclear determinant and regulates cell proliferation and fate during Xenopus neurogenesis (2009) (0)
- Document S1. Figures S1–S5 and Supplemental Experimental Procedures (2013) (0)
- 21-P019 The role of Sprouty3, a new signalling regulator, in Xenopus development (2009) (0)
- Editorial Board (2006) (0)
- 03-P114 Investigating the origin of long-term dividing neural progenitors during Xenopus development (2009) (0)
- Faculty Opinions recommendation of Dynamic ligand discrimination in the notch signaling pathway. (2018) (0)
- Sequential onset and concurrent expression of miR-9 genomic loci in single cells contributes to the temporal increase of mature miR-9 in zebrafish neurogenesis (2020) (0)
- XBF-1 is an anterior neural plate-specific, winged helix transcription factor that affects neural development in a concentration-dependent manner. A high concentration of XBF-1 results in suppression of endogenous neuronal differentiation and an expansion of undifferentiated neuroectoderm. Here we i (2000) (0)
- Quantitative single-cell live imaging links HES5 dynamics with cell-state and fate in murine neurogenesis (2019) (0)
- A dynamic and spatially periodic micro-pattern of HES5 expression underlies the probability of neuronal differentiation in the mouse spinal cord (2020) (0)
- 03-P049 Control of mitotic spindle orientation and position during epiboly (2009) (0)
- 03-P100 Timing of neuronal differentiation in the vertebrate telencephalon by the transcription factor FoxG1 and the co-repressor Xgrg-3 (2009) (0)
- Cell coupling compensates for changes in single-cell Her6 dynamics and provides phenotypic robustness (2022) (0)
- Publisher's Note (2019) (0)
- miR-9 mediated noise optimization of the her6 oscillator is needed for cell state progression in the Zebrafish hindbrain (2019) (0)
- Feedback motifs tuned by microRNAs in human transcriptional networks (2020) (0)
- 21-P050 The role of Alsin, a guanine exchange factor for Rab5 GTPase, in early Xenopus development (2009) (0)
- reabsorptionemerging role of pendrin in renal chloride (2011) (0)
- Primary neuronal differentiation and orientated cell division in Xenopus (2001) (0)
- Modeling the Hes 1 Oscillator in Neural Progenitor Maintenance (0)
- Sequential and additive expression of miR-9 precursors control timing of neurogenesis (2022) (0)
- Editorial Board (2006) (0)
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