Naomi Wray
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Australian statistical geneticist and researcher
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Why Is Naomi Wray Influential?
(Suggest an Edit or Addition)According to Wikipedia, Naomi Ruth Wray is an Australian statistical geneticist at the University of Queensland, where she is a Professorial Research Fellow at the Institute for Molecular Bioscience and an Affiliate Professor in the Queensland Brain Institute. She is also a National Health and Medical Research Council Principal Research Fellow and, along with Peter Visscher and Jian Yang, is one of the three executive team members of the NHMRC-funded Program in Complex Trait Genomics. Naomi pioneered the use of polygenic scores in human genetics, and has made significant contributions to both the development of methods and their clinical use.
Naomi Wray's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Biological Insights From 108 Schizophrenia-Associated Genetic Loci (2014) (6445)
- Common polygenic variation contributes to risk of schizophrenia and bipolar disorder (2009) (4437)
- 10 Years of GWAS Discovery: Biology, Function, and Translation. (2017) (2346)
- Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs (2013) (2011)
- Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression (2018) (1816)
- Heritability in the genomics era — concepts and misconceptions (2008) (1679)
- Genome-wide Association Analysis Identifies 14 New Risk Loci for Schizophrenia (2013) (1455)
- Analysis of shared heritability in common disorders of the brain (2016) (1385)
- Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets (2016) (1316)
- A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects: CNV Analysis Group and the Schizophrenia Working Group of the Psychiatric Genomics Consortium (2016) (1125)
- Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection (2018) (1124)
- Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions (2018) (1090)
- Genome-wide association study identifies 30 Loci Associated with Bipolar Disorder (2017) (998)
- A mega-analysis of genome-wide association studies for major depressive disorder (2013) (979)
- Estimating missing heritability for disease from genome-wide association studies. (2011) (978)
- Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies (2019) (871)
- DNA methylation age of blood predicts all-cause mortality in later life (2015) (871)
- A versatile gene-based test for genome-wide association studies. (2010) (816)
- Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects (2016) (736)
- Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders (2019) (724)
- DNA methylation-based measures of biological age: meta-analysis predicting time to death (2016) (699)
- Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways (2015) (676)
- Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index (2015) (666)
- Prediction of individual genetic risk to disease from genome-wide association studies. (2007) (613)
- Pitfalls of predicting complex traits from SNPs (2013) (612)
- Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs (2012) (599)
- Research review: Polygenic methods and their application to psychiatric traits. (2014) (580)
- Epigenetic Signatures of Cigarette Smoking (2016) (574)
- Estimation of pleiotropy between complex diseases using single-nucleotide polymorphism-derived genomic relationships and restricted maximum likelihood (2012) (547)
- Causal associations between risk factors and common diseases inferred from GWAS summary data (2017) (543)
- Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes (2017) (517)
- Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases. (2014) (510)
- Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned (2010) (430)
- Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis (2016) (424)
- The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936 (2015) (416)
- Genomewide Association for Major Depressive Disorder: A possible role for the presynaptic protein Piccolo (2008) (410)
- Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance components analysis (2015) (397)
- Mapping genomic loci implicates genes and synaptic biology in schizophrenia (2022) (361)
- GWAS on family history of Alzheimer’s disease (2018) (357)
- Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics (ConLiGen) Report (2013) (340)
- Large-scale genomics unveils the genetic architecture of psychiatric disorders (2014) (321)
- Statistical Power to Detect Genetic (Co)Variance of Complex Traits Using SNP Data in Unrelated Samples (2014) (315)
- Simultaneous Discovery, Estimation and Prediction Analysis of Complex Traits Using a Bayesian Mixture Model (2015) (312)
- The Genetic Interpretation of Area under the ROC Curve in Genomic Profiling (2010) (308)
- Harnessing the information contained within genome-wide association studies to improve individual prediction of complex disease risk. (2009) (308)
- Concepts, estimation and interpretation of SNP-based heritability (2017) (303)
- Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling (2015) (293)
- A Comparative Study of Techniques for Differential Expression Analysis on RNA-Seq Data (2014) (283)
- Partitioning the Heritability of Tourette Syndrome and Obsessive Compulsive Disorder Reveals Differences in Genetic Architecture (2013) (280)
- Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study (2016) (258)
- Signatures of negative selection in the genetic architecture of human complex traits (2018) (243)
- Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology (2021) (240)
- Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood (2018) (228)
- Improved polygenic prediction by Bayesian multiple regression on summary statistics (2019) (224)
- Polygenic Risk Score, Parental Socioeconomic Status, Family History of Psychiatric Disorders, and the Risk for Schizophrenia: A Danish Population-Based Study and Meta-analysis. (2015) (224)
- Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach (2017) (221)
- A resource-efficient tool for mixed model association analysis of large-scale data (2019) (220)
- A Better Coefficient of Determination for Genetic Profile Analysis (2012) (218)
- Joint Analysis of Psychiatric Disorders Increases Accuracy of Risk Prediction for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder (2015) (206)
- Joint Analysis of Psychiatric Disorders Increases Accuracy of Risk Prediction for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder (2015) (206)
- The epigenetic clock and telomere length are independently associated with chronological age and mortality (2016) (194)
- Common Disease Is More Complex Than Implied by the Core Gene Omnigenic Model (2018) (191)
- Using Summary Data from the Danish National Registers to Estimate Heritabilities for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder (2012) (190)
- Estimation and partitioning of polygenic variation captured by common SNPs for Alzheimer's disease, multiple sclerosis and endometriosis (2012) (190)
- Association between the TRAX/DISC locus and both bipolar disorder and schizophrenia in the Scottish population (2005) (188)
- Estimating Trait Heritability (2008) (185)
- Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium☆ (2017) (183)
- Integrative analysis of omics summary data reveals putative mechanisms underlying complex traits (2018) (182)
- A whole genome association study of neuroticism using DNA pooling (2008) (181)
- Genetic predisposition to schizophrenia associated with increased use of cannabis (2014) (181)
- Genes, Environment and Psychopathology: Understanding the Causes of Psychiatric and Substance Use Disorders (2007) (181)
- Genetic correlations of polygenic disease traits: from theory to practice (2019) (178)
- Prediction of individual genetic risk of complex disease. (2008) (176)
- Synthetic Associations Created by Rare Variants Do Not Explain Most GWAS Results (2011) (173)
- Polygenic transmission and complex neuro developmental network for attention deficit hyperactivity disorder: Genome‐wide association study of both common and rare variants (2013) (172)
- A direct test of the diathesis–stress model for depression (2017) (172)
- A genome-wide association study of Cloninger's temperament scales: Implications for the evolutionary genetics of personality (2010) (163)
- Cohort Profile Update: The Mater-University of Queensland Study of Pregnancy (MUSP). (2005) (160)
- Estimation and partition of heritability in human populations using whole-genome analysis methods. (2013) (156)
- Genetic Studies of Major Depressive Disorder: Why Are There No Genome-wide Association Study Findings and What Can We Do About It? (2014) (156)
- Prediction of rates of inbreeding in selected populations. (1990) (156)
- Estimating Effects and Making Predictions from Genome-Wide Marker Data (2010) (155)
- Genetic and environmental exposures constrain epigenetic drift over the human life course (2014) (152)
- Translation elongation factor eEF1A2 is a potential oncoprotein that is overexpressed in two-thirds of breast tumours (2005) (152)
- Genetic correlates of social stratification in Great Britain (2019) (148)
- Explaining additional genetic variation in complex traits. (2014) (147)
- Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations (2017) (146)
- Evidence-based psychiatric genetics, AKA the false dichotomy between common and rare variant hypotheses (2012) (146)
- GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores. (2019) (144)
- The contribution of genetic variants to disease depends on the ruler (2014) (144)
- A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment (2019) (138)
- A Genetic Investigation of Sex Bias in the Prevalence of Attention-Deficit/Hyperactivity Disorder (2017) (136)
- Hypermetabolism in ALS is associated with greater functional decline and shorter survival (2018) (135)
- GWAS of epigenetic aging rates in blood reveals a critical role for TERT (2017) (132)
- Identification of 55,000 Replicated DNA Methylation QTL (2017) (131)
- Genetic signatures of high-altitude adaptation in Tibetans (2017) (129)
- Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing (2019) (127)
- Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation (2020) (125)
- From Basic Science to Clinical Application of Polygenic Risk Scores: A Primer. (2020) (125)
- Epigenetic prediction of complex traits and death (2018) (123)
- Improving Phenotypic Prediction by Combining Genetic and Epigenetic Associations (2015) (120)
- Improving genetic prediction by leveraging genetic correlations among human diseases and traits (2018) (118)
- Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration (2019) (116)
- Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia (2011) (114)
- Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness (2017) (113)
- Narrowing the Boundaries of the Genetic Architecture of Schizophrenia (2009) (112)
- The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data (2011) (111)
- ASYMPTOTIC RATES OF RESPONSE FROM INDEX SELECTION (1989) (110)
- Accurate, Large-Scale Genotyping of 5HTTLPR and Flanking Single Nucleotide Polymorphisms in an Association Study of Depression, Anxiety, and Personality Measures (2009) (110)
- Could Polygenic Risk Scores Be Useful in Psychiatry?: A Review. (2020) (109)
- A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales (2012) (108)
- Sex-specific association between bipolar affective disorder in women and GPR50, an X-linked orphan G protein-coupled receptor (2005) (108)
- Genetic correlation between amyotrophic lateral sclerosis and schizophrenia (2017) (107)
- Shared Temperament Risk Factors for Anorexia Nervosa: A Twin Study (2008) (106)
- Allele frequencies and the r2 measure of linkage disequilibrium: impact on design and interpretation of association studies. (2005) (105)
- A genome‐wide association study of sleep habits and insomnia (2013) (105)
- Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology (2021) (104)
- Genome-wide association study of medication-use and associated disease in the UK Biobank (2019) (104)
- Monozygotic twins affected with major depressive disorder have greater variance in methylation than their unaffected co-twin (2013) (103)
- Sporadic cases are the norm for complex disease (2010) (102)
- Estimation of genetic correlation using linkage disequilibrium score regression and genomic restricted maximum likelihood (2017) (100)
- The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls (2018) (99)
- Estimation and partitioning of (co)heritability of inflammatory bowel disease from GWAS and immunochip data. (2014) (99)
- Autism-related dietary preferences mediate autism-gut microbiome associations (2021) (98)
- Project MinE: study design and pilot analyses of a large-scale whole-genome sequencing study in amyotrophic lateral sclerosis (2017) (97)
- Evidence of CNIH3 involvement in opioid dependence (2015) (96)
- Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders (2015) (95)
- Estimation of SNP heritability from dense genotype data. (2013) (94)
- Comparison of Genotypic and Phenotypic Correlations: Cheverud’s Conjecture in Humans (2018) (93)
- Genetic and environmental influences on the co‐morbidity between depression, panic disorder, agoraphobia, and social phobia: a twin study (2009) (92)
- Complement genes contribute sex-biased vulnerability in diverse illnesses (2020) (92)
- Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank (2019) (90)
- Risk of psychiatric illness from advanced paternal age is not predominantly from de novo mutations (2016) (89)
- Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium (2017) (87)
- Research review: the role of cytokines in depression in adolescents: a systematic review. (2013) (86)
- Hypermethylation in the ZBTB20 gene is associated with major depressive disorder (2014) (86)
- Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architecture (2020) (86)
- Predicting gene targets from integrative analyses of summary data from GWAS and eQTL studies for 28 human complex traits (2016) (85)
- Unraveling the Genetic Etiology of Adult Antisocial Behavior: A Genome-Wide Association Study (2012) (84)
- Multi-locus genome-wide association analysis supports the role of glutamatergic synaptic transmission in the etiology of major depressive disorder (2012) (82)
- Genetic and Phenotypic Stability of Measures of Neuroticism Over 22 Years (2007) (82)
- Genetic co-morbidity between neuroticism, anxiety/depression and somatic distress in a population sample of adolescent and young adult twins (2011) (81)
- DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons: Meta-analysis of Multiethnic Epigenome-wide Studies (2018) (79)
- Comparing apples and oranges: equating the power of case‐control and quantitative trait association studies (2009) (78)
- Multi-locus models of genetic risk of disease (2010) (77)
- Interpreting the role of de novo protein-coding mutations in neuropsychiatric disease (2013) (76)
- Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis (2017) (75)
- Additive genetic variation in schizophrenia risk is shared by populations of African and European descent. (2013) (74)
- Imprint of assortative mating on the human genome (2018) (74)
- Impact of diagnostic misclassification on estimation of genetic correlations using genome-wide genotypes (2012) (73)
- Prediction of asymptotic rates of response from selection on multiple traits using univariate and multivariate best linear unbiased predictors. (1993) (73)
- Where GWAS and epidemiology meet: opportunities for the simultaneous study of genetic and environmental risk factors in schizophrenia. (2013) (73)
- Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank (2019) (72)
- Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank (2019) (72)
- Complex Trait Prediction from Genome Data: Contrasting EBV in Livestock to PRS in Humans (2019) (70)
- Applying polygenic risk scores to postpartum depression (2014) (70)
- Association of OPRD1 polymorphisms with heroin dependence in a large case‐control series (2014) (67)
- Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors (2020) (66)
- NFIB-Mediated Repression of the Epigenetic Factor Ezh2 Regulates Cortical Development (2014) (66)
- Embracing polygenicity: a review of methods and tools for psychiatric genetics research (2017) (66)
- OSCA: a tool for omic-data-based complex trait analysis (2018) (66)
- Genetic Basis of Complex Genetic Disease: The Contribution of Disease Heterogeneity to Missing Heritability (2014) (64)
- Prediction of long-term contributions and inbreeding in populations undergoing mass selection (1993) (64)
- Underestimated Effect Sizes in GWAS: Fundamental Limitations of Single SNP Analysis for Dichotomous Phenotypes (2011) (61)
- Association study of candidate variants of COMT with neuroticism, anxiety and depression (2008) (60)
- A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts (2020) (60)
- The association between neonatal vitamin D status and risk of schizophrenia (2018) (60)
- ANKK1, TTC12, and NCAM1 polymorphisms and heroin dependence: importance of considering drug exposure. (2013) (59)
- A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases (2016) (59)
- Do 5HTTLPR and stress interact in risk for depression and suicidality? Item response analyses of a large sample (2009) (59)
- Evidence of causal effect of major depression on alcohol dependence: Findings from the Psychiatric Genomics Consortium (2018) (59)
- High loading of polygenic risk in cases with chronic schizophrenia (2016) (58)
- New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis. (2015) (58)
- DNA Modification Study of Major Depressive Disorder: Beyond Locus-by-Locus Comparisons (2015) (56)
- Anxiety and comorbid measures associated with PLXNA2. (2007) (55)
- The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25 000 subjects (2015) (55)
- Estimation of non-additive genetic variance in human complex traits from a large sample of unrelated individuals (2020) (54)
- GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression (2021) (54)
- CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits (2017) (52)
- Association of Mental Disorder in Childhood and Adolescence With Subsequent Educational Achievement. (2020) (52)
- C9orf72 hexanucleotide repeat expansions in Chinese sporadic amyotrophic lateral sclerosis (2015) (52)
- Overlap of expression Quantitative Trait Loci (eQTL) in human brain and blood (2014) (52)
- Dissection of genetic variation and evidence for pleiotropy in male pattern baldness (2018) (51)
- Assigning pedigree beef performance records to contemporary groups taking account of within-herd calving patterns (1997) (51)
- Purification of Neural Precursor Cells Reveals the Presence of Distinct, Stimulus-Specific Subpopulations of Quiescent Precursors in the Adult Mouse Hippocampus (2015) (50)
- Analysis of DNA methylation associates the cystine–glutamate antiporter SLC7A11 with risk of Parkinson’s disease (2020) (50)
- Common schizophrenia alleles are enriched in mutation-intolerant genes and maintained by background selection (2016) (50)
- Exploring Boundaries for the Genetic Consequences of Assortative Mating for Psychiatric Traits. (2016) (49)
- Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depressive disorder (2017) (47)
- 3GENOME-WIDE META-ANALYSIS OF DEPRESSION (2019) (47)
- Allele Frequencies and the r2 Measure of Linkage Disequilibrium: Impact on Design and Interpretation of Association Studies (2005) (46)
- A 3p26-3p25 genetic linkage finding for DSM-IV major depression in heavy smoking families. (2011) (46)
- Genome‐wide gene‐environment interaction in depression: A systematic evaluation of candidate genes (2018) (46)
- Evidence for Genetic Overlap Between Schizophrenia and Age at First Birth in Women. (2016) (45)
- Discovery and implications of polygenicity of common diseases (2021) (43)
- Genetic Differences between Five European Populations (2010) (43)
- Expression of eEF1A2 is associated with clear cell histology in ovarian carcinomas: overexpression of the gene is not dependent on modifications at the EEF1A2 locus (2007) (42)
- Association analysis of the chromosome 4p15–p16 candidate region for bipolar disorder and schizophrenia (2007) (42)
- Genome-wide linkage analysis of multiple measures of neuroticism of 2 large cohorts from Australia and the Netherlands. (2008) (41)
- Genome-wide meta-analysis of depression in 807,553 individuals identifies 102 independent variants with replication in a further 1,507,153 individuals (2018) (40)
- GCTA-GREML accounts for linkage disequilibrium when estimating genetic variance from genome-wide SNPs (2016) (40)
- Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs (2012) (40)
- Disease and Polygenic Architecture: Avoid Trio Design and Appropriately Account for Unscreened Control Subjects for Common Disease. (2016) (40)
- Accounting for Mutation Effects in the Additive Genetic Variance-Covariance Matrix and Its Inverse (1990) (39)
- Risk in Relatives, Heritability, SNP-Based Heritability, and Genetic Correlations in Psychiatric Disorders: A Review (2020) (39)
- Association of Schizophrenia Risk With Disordered Niacin Metabolism in an Indian Genome-wide Association Study. (2019) (37)
- Genetic Overlap Between Diagnostic Subtypes of Ischemic Stroke (2015) (37)
- Bayesian reassessment of the epigenetic architecture of complex traits (2018) (37)
- Testing the role of circadian genes in conferring risk for psychiatric disorders (2014) (37)
- Detection and quantification of inbreeding depression for complex traits from SNP data (2017) (37)
- Association of polygenic score for major depression with response to lithium in patients with bipolar disorder (2020) (37)
- Widespread signatures of natural selection across human complex traits and functional genomic categories (2021) (37)
- Using information of relatives in genomic prediction to apply effective stratified medicine (2017) (35)
- Genome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 1936 (2019) (35)
- Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders (2020) (35)
- Novel Genetic Analysis for Case-Control Genome-Wide Association Studies: Quantification of Power and Genomic Prediction Accuracy (2013) (34)
- Investigating Shared Genetic Basis Across Tourette Syndrome and Comorbid Neurodevelopmental Disorders Along the Impulsivity-Compulsivity Spectrum (2021) (33)
- Examining Sex-Differentiated Genetic Effects Across Neuropsychiatric and Behavioral Traits (2020) (33)
- Genome-wide analyses of behavioural traits are subject to bias by misreports and longitudinal changes (2021) (33)
- Genome-wide gene-environment analyses of depression and reported lifetime traumatic experiences in UK Biobank (2018) (32)
- Genome‐wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness (2016) (32)
- OSCA: a tool for omic-data-based complex trait analysis (2019) (32)
- A polygenic resilience score moderates the genetic risk for schizophrenia (2019) (31)
- Genome-wide Meta-analysis Finds the ACSL5-ZDHHC6 Locus Is Associated with ALS and Links Weight Loss to the Disease Genetics (2020) (30)
- Genome-wide Regional Heritability Mapping Identifies a Locus Within the TOX2 Gene Associated With Major Depressive Disorder (2017) (30)
- A Combined Pathway and Regional Heritability Analysis Indicates NETRIN1 Pathway Is Associated With Major Depressive Disorder (2017) (29)
- Genotype effects contribute to variation in longitudinal methylome patterns in older people (2018) (29)
- Suggestive linkage on chromosome 2, 8, and 17 for lifetime major depression (2009) (29)
- Meta-analyses of genome-wide linkage scans of anxiety-related phenotypes (2012) (29)
- Seasonality shows evidence for polygenic architecture and genetic correlation with schizophrenia and bipolar disorder. (2015) (28)
- Cohort profile: the Australian genetics of depression study (2020) (28)
- Rare DNA variants in the brain-derived neurotrophic factor gene increase risk for attention-deficit hyperactivity disorder: a next-generation sequencing study (2017) (28)
- Comorbid Chronic Pain and Depression: Shared Risk Factors and Differential Antidepressant Effectiveness (2020) (27)
- Methods for predicting rates of inbreeding in selected populations (2004) (27)
- Indivisible by Two: Lives of Extraordinary Twins (2005) (27)
- Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology (2021) (26)
- Gut microbiota in ALS: possible role in pathogenesis? (2019) (26)
- Quantifying between‐cohort and between‐sex genetic heterogeneity in major depressive disorder (2019) (26)
- Performance of risk prediction for inflammatory bowel disease based on genotyping platform and genomic risk score method (2017) (26)
- Association analysis of the chromosome 4p-located G protein-coupled receptor 78 (GPR78) gene in bipolar affective disorder and schizophrenia (2006) (25)
- Genotype–covariate correlation and interaction disentangled by a whole-genome multivariate reaction norm model (2018) (25)
- Complement genes contribute sex-biased vulnerability in diverse disorders (2020) (25)
- Commentary on “Limitations of GCTA as a solution to the missing heritability problem” (2016) (25)
- Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection (2018) (25)
- Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder (2018) (24)
- Sex differences in symptoms of depression in unrelated individuals and opposite-sex twin and sibling pairs. (2006) (24)
- Genetic Consequences of Social Stratification in Great Britain (2018) (24)
- 43 GENOME-WIDE ASSOCIATION ANALYSES IDENTIFY 44 RISK VARIANTS AND REFINE THE GENETIC ARCHITECTURE OF MAJOR DEPRESSIVE DISORDER (2019) (24)
- Extreme inbreeding in a European ancestry sample from the contemporary UK population (2019) (23)
- Consequences of selection in finite populations with particular reference to closed nucleus herds of pigs (1989) (23)
- Haplotypes of common SNPs can explain missing heritability of complex diseases (2015) (23)
- Identification of tag haplotypes for 5HTTLPR for different genome-wide SNP platforms (2011) (23)
- Use of monozygotic twins to investigate the relationship between 5HTTLPR genotype, depression and stressful life events: an application of Item Response Theory. (2008) (23)
- Appraisals of Stressful Life Events as a Genetically-Linked Mechanism in the Stress–Depression Relationship (2012) (23)
- Haplotype Analysis and a Novel Allele-Sharing Method Refines a Chromosome 4p Locus Linked to Bipolar Affective Disorder (2007) (23)
- Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell profiles and epigenetic ageing (2018) (23)
- Genome-wide association study identifies 30 loci associated with bipolar disorder (2019) (22)
- Corrigendum: The epigenetic clock and telomere length are independently associated with chronological age and mortality [Int J Epidemiol., 45, 2, (424-432)(2016)] DOI: 10.1093/ije/dyw041 (2016) (22)
- Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders (2021) (22)
- Rare Variant Burden Analysis within Enhancers Identifies CAV1 as an ALS Risk Gene (2020) (22)
- The epigenetic clock and telomere length are independently associated with chronological age and mortality (2017) (22)
- Regulatory variants explain much more heritability than coding variants across 11 common diseases (2014) (22)
- Concepts and Misconceptions about the Polygenic Additive Model Applied to Disease (2016) (21)
- Extra-motor abnormalities in amyotrophic lateral sclerosis: another layer of heterogeneity (2017) (21)
- Genome-wide association study of dietary intake in the UK biobank study and its associations with schizophrenia and other traits (2020) (21)
- Association study of candidate variants from brain-derived neurotrophic factor and dystrobrevin-binding protein 1 with neuroticism, anxiety, and depression (2008) (21)
- A recessive genetic model and runs of homozygosity in major depressive disorder (2014) (20)
- Familiality of Psychiatric Disorders and Risk of Postpartum Psychiatric Episodes: A Population-Based Cohort Study. (2018) (20)
- Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression (2020) (20)
- Genetic risk scores for major psychiatric disorders and the risk of postpartum psychiatric disorders (2019) (19)
- Is Schizophrenia a Risk Factor for Breast Cancer?-Evidence From Genetic Data. (2018) (19)
- Whole-exome sequencing in amyotrophic lateral sclerosis suggests NEK1 is a risk gene in Chinese (2017) (19)
- Identifying the Common Genetic Basis of Antidepressant Response (2021) (19)
- Progression and survival of patients with motor neuron disease relative to their fecal microbiota (2020) (19)
- Across-cohort QC analyses of GWAS summary statistics from complex traits (2016) (18)
- Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS (2022) (18)
- Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank (2019) (18)
- A comprehensive evaluation of polygenic score methods across cohorts in psychiatric disorders (2020) (18)
- Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults (2020) (18)
- Trajectories of maternal depression: a 27-year population-based prospective study (2016) (18)
- Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS (2022) (18)
- Genotype–covariate correlation and interaction disentangled by a whole-genome multivariate reaction norm model (2019) (18)
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- Author and Subject Index (2016) (0)
- Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection (2019) (0)
- Author Correction: From Mendel to quantitative genetics in the genome era: the scientific legacy of W. G. Hill (2022) (0)
- Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank Working of the Psychiatric Genomics Consortium (2019) (0)
- Genome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 1936 (2019) (0)
- VKučinskas-2001-2016 (2016) (0)
- The genetic and phenotypic correlates of neonatal Complement Component 3 and 4 protein concentrations with a focus on psychiatric and autoimmune disorders (2022) (0)
- Genetic control of temperament traits across species: association of autism spectrum disorder risk genes with cattle temperament (2020) (0)
- Genetic and epigenetic architectures of neurological protein biomarkers in the Lothian Birth Cohort 1936 (2019) (0)
- Genome-wide association study in an Indian population reveals genetic overlap for schizophrenia with Europeans (2017) (0)
- A Family With Multiple Cases of Schizophrenia and Mild Intellectual Impairment Also Associated With Retinitis Pigmentosa and / or Progressive Hearing Loss (2013) (0)
- The association between neonatal vitamin D status and risk of schizophrenia (2018) (0)
- Characterizing an inverse axis between orthogonal sources of genetic risk (2015) (0)
- Overlap of expression Quantitative Trait Loci (eQTL) in human brain and blood (2014) (0)
- Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder (2018) (0)
- Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions (2019) (0)
- Epigenetic prediction of complex traits and death (2018) (0)
- Interactions between the lipidome and genetic and environmental factors in autism (2023) (0)
- Genetic association study of childhood aggression across raters, instruments, and age. (2021) (0)
- GWAS of epigenetic aging rates in blood reveals a critical role for TERT (2018) (0)
- A Combined Pathway and Regional Heritability Analysis Indicates NETRIN 1 Pathway is Associated with Major Depressive Disorder Short title : pathway and regional heritability analyses in MDD (2016) (0)
- Timing of Antidepressant Discontinuation During Pregnancy and Postpartum Psychiatric Outcomes in Denmark and Norway (2023) (0)
- THEME 12A SCIENTIFIC WORK IN PROGRESS SW1 WHOLE EXOME SEQUENCING OF ALS CASES AND CONTROL: A PILOT STUDY (2014) (0)
- Fine-mapping reveals complex genetic architecture underlying DNA methylation (2018) (0)
- 30ENVIRONMENTAL FACTORS ARE OFTEN HERITABLE: DOES THIS BIAS POLYGENIC GENE-BY-ENVIRONMENT INTERACTION ANALYSES? (2019) (0)
- Trans-eQTLs identified in whole blood have limited influence on complex disease biology (2018) (0)
- Author Correction: Misestimation of heritability and prediction accuracy of male-pattern baldness (2018) (0)
- A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment (2019) (0)
- Genome-wide association analyses identify 44 risk variants and refine the genetic architecture ofmajor depressive disorder (2018) (0)
- Author Correction: Misestimation of heritability and prediction accuracy of male-pattern baldness (2018) (0)
- A resource-efficient tool for mixed model association analysis of large-scale data (2019) (0)
- GWAS of major depressive disorder (2011) (0)
- 19 INVESTIGATING CAUSAL RELATIONSHIPS BETWEEN MAJOR DEPRESSIVE DISORDER AND GENETICALLY CORRELATED TRAITS USING MENDELIAN RANDOMISATION (2019) (0)
- Author's response to reviews Title:Overlap of Expression Quantitative Trait Loci (eQTL) in Human Brain and Blood Authors: (0)
- 18 VALIDATING GWA ASSOCIATIONS IN PSYCHIATRIC DISORDERS WITH FUNCTIONAL GENOMIC DATA (2019) (0)
- Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology (2022) (0)
- RNA-seq analysis of skeletal muscle in motor neurone disease cases and controls (2023) (0)
- Polygenic burden could explain high rates of affective disorders in a community with restricted founder population (2021) (0)
- Author's response to reviews Title:Overlap of Expression Quantitative Trait Loci (eQTL) in Human Brain and Blood Authors: (0)
- Students', colleagues' and research partners' experience about work and accomplishments from collaborating with Robin Thompson. (2019) (0)
- Association between DISC1 polymorphisms and major mental illness in the Scottish population (2004) (0)
- A study of genetic influence on SPHERE (somatic and psychological health report) measures collected in adolescents and young adults (2010) (0)
- Using C-Reactive Protein Genetic Profile Scores to Predict Risk of Anxiety (2015) (0)
- Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson’s disease heritability (2019) (0)
- Genome-wide analyses of behavioural traits are subject to bias by misreports and longitudinal changes (2021) (0)
- Misestimation of heritability and prediction accuracy of male-pattern baldness (2018) (0)
- Investigating the potential effect of antihypertensive medication on psychiatric disorders: a mendelian randomisation study (2020) (0)
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