Naoyuki Takahashi
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Biology
Naoyuki Takahashi's Degrees
- PhD Pharmaceutical Sciences University of Tokyo
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(Suggest an Edit or Addition)Naoyuki Takahashi's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. (1998) (4178)
- Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. (1999) (2258)
- IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. (1999) (1734)
- Tumor Necrosis Factor α Stimulates Osteoclast Differentiation by a Mechanism Independent of the Odf/Rankl–Rank Interaction (2000) (1254)
- Modulation of osteoclast differentiation. (1992) (1067)
- Origin of osteoclasts: mature monocytes and macrophages are capable of differentiating into osteoclasts under a suitable microenvironment prepared by bone marrow-derived stromal cells. (1990) (991)
- Osteoblastic cells are involved in osteoclast formation. (1988) (945)
- Soluble interleukin-6 receptor triggers osteoclast formation by interleukin 6. (1993) (832)
- Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage [published erratum appears in J Cell Biol 1995 Feb;128(4):following 713] (1994) (801)
- Osteoclast-like cell formation and its regulation by osteotropic hormones in mouse bone marrow cultures. (1988) (779)
- Bone Morphogenetic Protein-2 Converts the Differentiation Pathway of C2C12 Myoblasts into the Osteoblast Lineage (2002) (669)
- Regulatory mechanisms of osteoblast and osteoclast differentiation. (2002) (609)
- Macrophage colony-stimulating factor is indispensable for both proliferation and differentiation of osteoclast progenitors. (1993) (566)
- Interleukin‐6 and soluble interleukin‐6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast‐like cell formation (1996) (546)
- The bone marrow-derived stromal cell lines MC3T3-G2/PA6 and ST2 support osteoclast-like cell differentiation in cocultures with mouse spleen cells. (1989) (485)
- Activated human T cells directly induce osteoclastogenesis from human monocytes: possible role of T cells in bone destruction in rheumatoid arthritis patients. (2001) (445)
- Regulation of Osteoclast Function (1997) (433)
- Osteoblasts/stromal cells stimulate osteoclast activation through expression of osteoclast differentiation factor/RANKL but not macrophage colony-stimulating factor: receptor activator of NF-kappa B ligand. (1999) (430)
- Osteoclast differentiation factor acts as a multifunctional regulator in murine osteoclast differentiation and function. (1999) (425)
- Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis (2012) (412)
- Osteoprotegerin produced by osteoblasts is an important regulator in osteoclast development and function. (2000) (397)
- Interleukin (IL)-6 induction of osteoclast differentiation depends on IL-6 receptors expressed on osteoblastic cells but not on osteoclast progenitors (1995) (371)
- Osteoclast differentiation factor (ODF) induces osteoclast-like cell formation in human peripheral blood mononuclear cell cultures. (1998) (357)
- Interleukin 1 induces multinucleation and bone-resorbing activity of osteoclasts in the absence of osteoblasts/stromal cells. (1999) (349)
- Modulation of osteoclast differentiation by local factors. (1995) (338)
- Transforming Growth Factor β Affects Osteoclast Differentiation via Direct and Indirect Actions (2001) (283)
- p38 MAPK-mediated signals are required for inducing osteoclast differentiation but not for osteoclast function. (2002) (274)
- A novel molecular mechanism modulating osteoclast differentiation and function. (1999) (264)
- Role of prostaglandins in interleukin‐1‐induced bone resorption in mice in vitro (1991) (259)
- The murine glucagon-like peptide-1 receptor is essential for control of bone resorption. (2008) (258)
- Identification of a BMP‐responsive element in Id1, the gene for inhibition of myogenesis (2002) (258)
- Bone Morphogenetic Protein 2 Stimulates Osteoclast Differentiation and Survival Supported by Receptor Activator of Nuclear Factor-κB Ligand. (2001) (229)
- A possible mechanism of the specific action of bisphosphonates on osteoclasts: tiludronate preferentially affects polarized osteoclasts having ruffled borders. (1995) (226)
- Central control of fever and female body temperature by RANKL/RANK (2009) (219)
- Activation of NF-κB Is Involved in the Survival of Osteoclasts Promoted by Interleukin-1* (1998) (195)
- Prostaglandins promote osteoclastlike cell formation by a mechanism involving cyclic adenosine 3′,5′‐monophosphate in mouse bone marrow cell cultures (1989) (193)
- Recombinant human interferon-gamma inhibits formation of human osteoclast-like cells. (1986) (187)
- Gastric inhibitory polypeptide as an endogenous factor promoting new bone formation after food ingestion. (2006) (186)
- Osteoprotegerin regulates bone formation through a coupling mechanism with bone resorption. (2003) (185)
- Role of colony‐stimulating factors in osteoclast development (1991) (184)
- Role of 1 alpha,25-dihydroxyvitamin D3 in osteoclast differentiation and function. (1997) (181)
- Induction of calcitonin receptors by 1 alpha, 25-dihydroxyvitamin D3 in osteoclast-like multinucleated cells formed from mouse bone marrow cells. (1988) (180)
- Lipopolysaccharide Promotes the Survival of Osteoclasts Via Toll-Like Receptor 4, but Cytokine Production of Osteoclasts in Response to Lipopolysaccharide Is Different from That of Macrophages 1 (2003) (180)
- The small GTP-binding protein, rho p21, is involved in bone resorption by regulating cytoskeletal organization in osteoclasts. (1995) (179)
- Fibroblastic cells derived from bovine periodontal ligaments have the phenotypes of osteoblasts. (1990) (178)
- Osteoclast function is activated by osteoblastic cells through a mechanism involving cell-to-cell contact. (1996) (169)
- Action of RANKL and OPG for osteoclastogenesis. (2009) (164)
- A critical role for interleukin-6 family-mediated Stat3 activation in osteoblast differentiation and bone formation. (2006) (164)
- Formation of multinucleated cells that respond to osteotropic hormones in long term human bone marrow cultures. (1987) (161)
- Deficiency of osteoclasts in osteopetrotic mice is due to a defect in the local microenvironment provided by osteoblastic cells. (1991) (160)
- Suppression of Osteoprotegerin Expression by Prostaglandin E2 Is Crucially Involved in Lipopolysaccharide-Induced Osteoclast Formation1 (2004) (157)
- Preparation and characterization of a mouse osteoclast‐like multinucleated cell population (1992) (157)
- Identification of cell cycle–arrested quiescent osteoclast precursors in vivo (2009) (155)
- Wortmannin, a specific inhibitor of phosphatidylinositol‐3 kinase, blocks osteoclastic bone resorption (1995) (149)
- Regulation of bone metabolism by Wnt signals. (2016) (142)
- Effect of a continuously applied compressive pressure on mouse osteoblast‐like cells (MC3T3‐E1) in vitro (1990) (142)
- Parathyroid hormone regulates osteoblast differentiation positively or negatively depending on the differentiation stages (1996) (142)
- Noncanonical Wnt5a enhances Wnt/β-catenin signaling during osteoblastogenesis (2014) (136)
- MyD88 But Not TRIF Is Essential for Osteoclastogenesis Induced by Lipopolysaccharide, Diacyl Lipopeptide, and IL-1α (2004) (133)
- The molecular mechanism of osteoclastogenesis in rheumatoid arthritis (2002) (131)
- Vitamin D endocrine system and osteoclasts (2014) (129)
- The molecular basis of osteoclast differentiation and activation. (2001) (128)
- Prostaglandin E2 Enhances Osteoclastic Differentiation of Precursor Cells through Protein Kinase A-dependent Phosphorylation of TAK1* (2005) (128)
- Tyrosine Phosphorylation of p130Cas Is Involved in Actin Organization in Osteoclasts* (1998) (123)
- Recombinant human transforming growth factor-alpha stimulates the formation of osteoclast-like cells in long-term human marrow cultures. (1986) (121)
- Regulatory mechanism of osteoclastogenesis by RANKL and Wnt signals. (2011) (115)
- Chemical and physical properties of the extracellular matrix are required for the actin ring formation in osteoclasts (1996) (112)
- IL-34 and CSF-1: similarities and differences (2013) (108)
- Parathyroid hormone (PTH)-related protein is a potent stimulator of osteoclast-like multinucleated cell formation to the same extent as PTH in mouse marrow cultures. (1989) (105)
- Roles of macrophage-colony stimulating factor and osteoclast differentiation factor in osteoclastogenesis (2000) (102)
- Bone morphogenetic protein 2 stimulates osteoclast differentiation and survival supported by receptor activator of nuclear factor-kappaB ligand. (2001) (101)
- Osteoclasts express high levels of p60c‐src , preferentially on ruffled border membranes (1992) (94)
- Fos plays an essential role in the upregulation of RANK expression in osteoclast precursors within the bone microenvironment (2012) (94)
- New resorption assay with mouse osteoclast‐like multinucleated cells formed in vitro (1993) (93)
- p38 Mitogen-activated protein kinase is crucially involved in osteoclast differentiation but not in cytokine production, phagocytosis, or dendritic cell differentiation of bone marrow macrophages. (2003) (92)
- Cloning of an osteoblastic cell line involved in the formation of osteoclast‐like cells (1990) (91)
- Roles of Wnt signals in bone resorption during physiological and pathological states (2012) (91)
- Intracellular Calcium and Protein Kinase C Mediate Expression of Receptor Activator of Nuclear Factor-κB Ligand and Osteoprotegerin in Osteoblasts. (2000) (88)
- Lineage‐committed osteoclast precursors circulate in blood and settle down into bone (2011) (87)
- Interleukin-1 Activates an NF-B-like Factor in Osteoclast-like Cells (*) (1996) (87)
- Cells of Bone (2002) (87)
- Role of vitamin D in bone resorption (1992) (86)
- Prostaglandin E2 strongly inhibits human osteoclast formation. (2005) (84)
- New roles of osteoblasts involved in osteoclast differentiation. (2012) (77)
- Importance of Membrane‐ or Matrix‐Associated Forms of M‐CSF and RANKL/ODF in Osteoclastogenesis Supported by SaOS‐4/3 Cells Expressing Recombinant PTH/PTHrP Receptors (2000) (76)
- Regulation of osteoclast polarization (2007) (76)
- Daily administration of eldecalcitol (ED‐71), an active vitamin D analog, increases bone mineral density by suppressing RANKL expression in mouse trabecular bone (2012) (76)
- Osteoclast-like cells form in long-term human bone marrow but not in peripheral blood cultures. (1989) (74)
- Multiwalled carbon nanotubes specifically inhibit osteoclast differentiation and function. (2009) (73)
- Tiludronate inhibits protein tyrosine phosphatase activity in osteoclasts. (1997) (73)
- Generating murine osteoclasts from bone marrow. (2003) (73)
- Muramyl Dipeptide Enhances Osteoclast Formation Induced by Lipopolysaccharide, IL-1α, and TNF-α through Nucleotide-Binding Oligomerization Domain 2-Mediated Signaling in Osteoblasts1 (2005) (69)
- Mouse primary osteoblasts express vitamin D3 25-hydroxylase mRNA and convert 1α-hydroxyvitamin D3 into 1α,25-dihydroxyvitamin D3 (1995) (69)
- Extremely high circulating levels of 1 alpha,25-dihydroxyvitamin D3 in the marmoset, a new world monkey. (1983) (68)
- A Jak1/2 inhibitor, baricitinib, inhibits osteoclastogenesis by suppressing RANKL expression in osteoblasts in vitro (2017) (67)
- Phosphatidylinositol‐3 kinase is involved in ruffled border formation in osteoclasts (1997) (67)
- Spleen serves as a reservoir of osteoclast precursors through vitamin D-induced IL-34 expression in osteopetrotic op/op mice (2012) (66)
- Generation of osteoclasts in vitro, and assay of osteoclast activity. (2007) (64)
- A differentiation‐inducing factor produced by the osteoblastic cell line MC3T3‐E1 stimulates bone resorption by promoting osteoclast formation (1988) (62)
- Osteoblasts provide a suitable microenvironment for the action of receptor activator of nuclear factor-kappaB ligand. (2006) (59)
- Lack of vacuolar proton ATPase association with the cytoskeleton in osteoclasts of osteosclerotic (oc/oc) mice (1997) (59)
- Chondromodulin I Is a Bone Remodeling Factor (2003) (57)
- Multinucleated cells formed on calcified dentine from mouse bone marrow cells treated with 1α,25‐dihydroxyvitamin D3 have ruffled borders and resorb dentine (1989) (56)
- Bone effects of vitamin D - Discrepancies between in vivo and in vitro studies. (2012) (56)
- Continuously applied compressive pressure induces bone resorption by a mechanism involving prostaglandin E2 synthesis (1990) (56)
- Erratum: Osteoclast function is activated by osteoblastic cells through a mechanism involving cell-to-cell contact (Endocrinology 137 (2187-2190)) (1996) (55)
- Human osteoclast-like cells are formed from peripheral blood mononuclear cells in a coculture with SaOS-2 cells transfected with the parathyroid hormone (PTH)/PTH-related protein receptor gene. (1999) (54)
- Prostaglandins promote osteoclast-like cell formation by a mechanism involving cyclic adenosine 3',5'-monophosphate in mouse bone marrow cell cultures. (1989) (53)
- Bone Formation Is Coupled to Resorption Via Suppression of Sclerostin Expression by Osteoclasts (2017) (53)
- Carbon Nanotubes Induce Bone Calcification by Bidirectional Interaction with Osteoblasts (2012) (53)
- The regulation of osteoclast differentiation by Wnt signals. (2013) (52)
- Protein kinase N3 promotes bone resorption by osteoclasts in response to Wnt5a-Ror2 signaling (2017) (52)
- Osteoclastic bone resorption induced by innate immune responses. (2010) (52)
- Intracellular calcium and protein kinase C mediate expression of receptor activator of nuclear factor-kappaB ligand and osteoprotegerin in osteoblasts. (2000) (49)
- Induction of spermidine N1-acetyltransferase by 1 alpha,25-dihydroxyvitamin D3 as an early common event in the target tissues of vitamin D. (1985) (49)
- Roles of Wnt signaling in bone formation and resorption (2008) (48)
- Osteoprotegerin Reduces the Serum Level of Receptor Activator of NF-κB Ligand Derived from Osteoblasts1 (2007) (48)
- Salmon calcitonin-induced stimulation of 1 alpha,25-dihydroxycholecalciferol synthesis in rats involving a mechanism independent of adenosine 3':5'-cyclic monophosphate. (1979) (47)
- Osteoprotegerin-deficient male mice as a model for severe alveolar bone loss: comparison with RANKL-overexpressing transgenic male mice. (2013) (47)
- Function of OPG as a traffic regulator for RANKL is crucial for controlled osteoclastogenesis (2010) (45)
- Prolonged decrease of serum calcium concentration by murine gamma-interferon in hypercalcemic, human tumor (EC-GI)-bearing nude mice. (1992) (45)
- Possible involvement of focal adhesion kinase, p125FAK, in osteoclastic bone resorption (1995) (44)
- VDR in Osteoblast‐Lineage Cells Primarily Mediates Vitamin D Treatment‐Induced Increase in Bone Mass by Suppressing Bone Resorption (2017) (44)
- Increased bone mass in mice after single injection of anti-receptor activator of nuclear factor-kappaB ligand-neutralizing antibody: evidence for bone anabolic effect of parathyroid hormone in mice with few osteoclasts. (2011) (44)
- Osteoclast function is activated by osteoblastic cells through a mechanism involving cell-to-cell contact. (1996) (43)
- Coordination of microtubules and the actin cytoskeleton is important in osteoclast function, but calcitonin disrupts sealing zones without affecting microtubule networks. (2006) (41)
- Regulation of osteoclast function (2012) (41)
- Alisol-B, a novel phyto-steroid, suppresses the RANKL-induced osteoclast formation and prevents bone loss in mice. (2010) (41)
- Increased Bone Mass in Mice after Single Injection of Anti-receptor Activator of Nuclear Factor-κB Ligand-neutralizing Antibody (2011) (40)
- The mechanism of end-organ resistance to 1 alpha,25-dihydroxycholecalciferol in the common marmoset. (1985) (39)
- Wnt16 regulates osteoclast differentiation in conjunction with Wnt5a. (2015) (39)
- Prostaglandin E2 Receptors EP2 and EP4 Are Down-regulated during Differentiation of Mouse Osteoclasts from Their Precursors* (2005) (38)
- Tetracyclines Convert the Osteoclastic-Differentiation Pathway of Progenitor Cells To Produce Dendritic Cell-like Cells (2012) (37)
- Diphenylhydantoin Inhibits Osteoclast Differentiation and Function Through Suppression of NFATc1 Signaling (2009) (35)
- Destruxins, cyclodepsipeptides, block the formation of actin rings and prominent clear zones and ruffled borders in osteoclasts. (2003) (34)
- Involvement of vacuolar H+ -ATPase in incorporation of risedronate into osteoclasts. (2003) (34)
- Muramyl dipeptide enhances osteoclast formation induced by lipopolysaccharide, IL-1 alpha, and TNF-alpha through nucleotide-binding oligomerization domain 2-mediated signaling in osteoblasts. (2005) (33)
- Ornithine decarboxylase activity in chick duodenum induced by 1 alpha, 25-dihydroxycholecalciferol. (1981) (33)
- Mechanisms involved in bone resorption regulated by vitamin D (2017) (33)
- Treatment of OPG-deficient mice with WP9QY, a RANKL-binding peptide, recovers alveolar bone loss by suppressing osteoclastogenesis and enhancing osteoblastogenesis (2017) (33)
- Osteogenic Factor Runx2 Marks a Subset of Leptin Receptor-Positive Cells that Sit Atop the Bone Marrow Stromal Cell Hierarchy (2017) (33)
- Roles of cathelicidins in inflammation and bone loss (2014) (29)
- Osteoclast‐like cell formation in fetal and newborn long‐term baboon marrow cultures is more sensitive to 1,25‐dihydroxyvitamin D3 than adult long‐term marrow cultures (1987) (29)
- New 19-nor-(20S)-1alpha,25-dihydroxyvitamin D3 analogs strongly stimulate osteoclast formation both in vivo and in vitro. (2007) (29)
- Isolation and characterization of osteoclast precursors that differentiate into osteoclasts on calvarial cells within a short period of time (1998) (28)
- CHAPTER 38 – Vitamin D and Osteoclastogenesis (1997) (28)
- Roles of cathelicidin‐related antimicrobial peptide in murine osteoclastogenesis (2013) (28)
- Bone in the marmoset: A resemblance to vitamin D-dependent rickets, type II (1986) (28)
- Stability of mRNA influences osteoporotic bone mass via CNOT3 (2014) (27)
- A rapid and sensitive in vitro assay of 25-hydroxyvitamin D3-1 alpha-hydroxylase and 24-hydroxylase using rat kidney homogenates. (1984) (27)
- Glucocorticoid regulation of calcitonin receptor in mouse osteoclast‐like multinucleated cells (1994) (26)
- The possible role of calcium-binding protein induced by 1 alpha,25-dihydroxyvitamin D3 in the intestinal calcium transport mechanism. (1982) (26)
- Lack of bone resorption in osteosclerotic (oc/oc) mice is due to a defect in osteoclast progenitors rather than the local microenvironment provided by osteoblastic cells. (1992) (25)
- Interleukin-1 alpha activates an NF-kappaB-like factor in osteoclast-like cells. (1996) (25)
- Mouse primary osteoblasts express vitamin D3 25-hydroxylase mRNA and convert 1 alpha-hydroxyvitamin D3 into 1 alpha,25-dihydroxyvitamin D3. (1995) (24)
- c-Fms Signaling Mediates Neurofibromatosis Type-1 Osteoclast Gain-In-Functions (2012) (24)
- Parathyroid Hormone Shifts Cell Fate of a Leptin Receptor‐Marked Stromal Population from Adipogenic to Osteoblastic Lineage (2019) (24)
- Ca2+-ATPase inhibitors and Ca2+-ionophore induce osteoclast-like cell formation in the cocultures of mouse bone marrow cells and calvarial cells. (1997) (24)
- Transcytosis of calcium from bone by osteoclast-like cells evidenced by direct visualization of calcium in cells. (2005) (23)
- Polarized osteoclasts put marks of tartrate-resistant acid phosphatase on dentin slices--a simple method for identifying polarized osteoclasts. (2011) (23)
- The site of 1α,25-dihydroxyvitamin D3 production in pregnancy (1979) (23)
- Stimulatory effect of prostaglandin E2 on 1 alpha,25-dihydroxyvitamin D3 synthesis in rats. (1983) (22)
- MKK6-p38 MAPK signaling pathway enhances survival but not bone-resorbing activity of osteoclasts. (2008) (22)
- The relationship between calcium accumulation in osteoclast mitochondrial granules and bone resorption. (2009) (21)
- An Ultrastructural Study of Cell-Cell Contact between Mouse Spleen Cells and Calvaria-Derived Osteoblastic Cells in a Co-Culture System for Osteoclast Formation (1997) (21)
- Hypergravity suppresses bone resorption in ovariectomized rats (2011) (20)
- A high-affinity cytosol binding protein for 1 alpha,25-dihydroxycholecalciferol in the uterus of Japanese quail. (1980) (20)
- Mechanism of inhibitory action of Eldecalcitol, an active vitamin D analog, on bone resorption in vivo (2013) (18)
- Dolomite supplementation improves bone metabolism through modulation of calcium-regulating hormone secretion in ovariectomized rats (2004) (17)
- Luman is involved in osteoclastogenesis through the regulation of DC-STAMP expression, stability and localization (2015) (17)
- Cells of BoneOsteoclast Generation (2002) (16)
- Establishment of primary cultures for mouse ameloblasts as a model of their lifetime. (2006) (14)
- 1α,25‐Dihydroxyvitamin D3 modulation in lipid metabolism in established bone marrow‐derived stromal cells, MC3T3‐G2/PA6 (1992) (14)
- Murine osteoclasts secrete serine protease HtrA1 capable of degrading osteoprotegerin in the bone microenvironment (2019) (13)
- Membrane-associated interleukin-1 promotes osteoclast-like cell formation in vitro. (1994) (12)
- [Control of bone resorption by RANKL-RANK system]. (2011) (12)
- Isolation and identificaton of 25-hydroxy-24-oxocholecalciferol: a metabolite of 25-hydroxycholecalciferol. (1980) (12)
- The common marmoset as an animal model for vitamin D-dependent rickets, type II. (1986) (12)
- Expression of mouse osteocalcin transcripts, OG1 and OG2, is differently regulated in bone tissues and osteoblast cultures (2001) (12)
- 1 alpha,25-dihydroxyvitamin D3 receptors and their action in embryonic chick chondrocytes. (1985) (11)
- Arctigenin Inhibits Osteoclast Differentiation and Function by Suppressing Both Calcineurin-Dependent and Osteoblastic Cell-Dependent NFATc1 Pathways (2014) (11)
- Nurse-like cells from patients with rheumatoid arthritis support the survival of osteoclast precursors via macrophage colony-stimulating factor production. (2005) (11)
- Distribution of ornithine decarboxylase activity induced by 1 alpha,25-dihydroxyvitamin D3 in chick duodenal villus mucosa. (1982) (11)
- The dynamin inhibitor dynasore inhibits bone resorption by rapidly disrupting actin rings of osteoclasts (2016) (10)
- Sclerostin expression in trabecular bone is downregulated by osteoclasts (2020) (10)
- 1α,25-Dihydroxyvitamin D3 receptors and their action in embryonic chick chondrocytes (2007) (10)
- Macrophage colon-stimulating factor (M-CSF) is essential for differentiation rather than proliferation of osteoclast progenitors (2005) (10)
- A stable analogue of thromboxane A2, 9,11-epithio-11,12-methanothromboxane A2, stimulates bone resorption in vitro and osteoclast-like cell formation in mouse marrow culture. (1991) (10)
- Docetaxel inhibits bone resorption through suppression of osteoclast formation and function in different manners (2009) (10)
- The role of vitamin D in the medullary bone formation in egg-laying japanese quail and in immature male chicks treated with sex hormones (1983) (9)
- Effects of calcitonin on the function of human osteoclast-like cells formed from CD14-positive monocytes. (2006) (8)
- The Vitamin D Receptor in Osteoblast-Lineage Cells Is Essential for the Proresorptive Activity of 1α,25(OH)2D3 In Vivo (2020) (8)
- Identification of cell cycle-arrested quiescent osteoclast precursors in vivo. (2010) (8)
- Minocycline to be used a potential anti-bone resorption agents due to the suppression of osteoclastic bone resorption (2013) (6)
- [A new treatment for osteoporosis using fully human monoclonal antibody to RANKL, AMG 162]. (2005) (6)
- Contributions to osteoclast biology from Japan. (2008) (6)
- The role of vitamin D metabolites in the treatment of osteoporosis (1995) (6)
- Chapter 9 – Osteoclast Generation (2008) (5)
- Protein kinase N 3 promotes bone resorption by osteoclasts in response to Wnt 5 a-Ror 2 signaling (2017) (4)
- Osteoblastic cells are prerequisite for inducing not only osteoclast differentiation but also function (1995) (4)
- The molecular mechanism of osteoclastogenesis: ODF/RANKL-dependent and independent pathways (2001) (4)
- Osteoclastogenesis and Vitamin D (2018) (3)
- Ror2 signaling enhances osteoclast formation in physiological and pathological conditions (2009) (3)
- Polarization of osteoclasts on dental implant materials is similar to that observed on bone (2014) (3)
- [Bone destruction caused by osteoclasts]. (2006) (3)
- Osteogenic Factor Runx2 Marks a Subset of Leptin Receptor-Positive Cells that Sit Atop the Bone Marrow Stromal Cell Hierarchy (2017) (3)
- [Regulatory mechanism of bone resorption: roles of bone remodeling-regulatory cytokines 'osteokines' in osteoclast differentiation and function]. (2003) (3)
- Bacterial components and bone resorption (2005) (3)
- Regulation and its refractoriness of 25-hydroxyvitamin D3 metabolism in vitamin D deficiency. (1981) (2)
- The Mechanism of Coupling between Bone Resorption and Formation (2006) (2)
- Osteoblasts Play Important Roles in Osteoclastogenesis through Offering the Critical Microenvironment for the Action of RANKL (2007) (2)
- [Origin of osteoclasts and the role of osteoblasts in osteoclast differentiation]. (1991) (2)
- Ornithine decarboxylase activity in chick duodenum induced by 1 a,25-dihydroxycholecalciferol (2005) (2)
- Regulatory mechanism of osteoclastogenesis by Wnt signaling (2011) (2)
- [Bone and bone related biochemical examinations. Bone and collagen related metabolites. Regulatory mechanisms of osteoclast differentiation and function]. (2006) (2)
- Osteoclasts (2020) (2)
- The site of 1 alpha,25-dihydroxyvitamin D3 production in pregnancy. (1979) (2)
- [Possible role of receptor activator of NF-kappa B ligand(RANKL) in osteoclast differentiation and function]. (2002) (1)
- [The pathophysiology of osteoporosis/osteopenia in gene mutant mice]. (2006) (1)
- [Role of osteoclast differentiation factor, the new member of the TNF ligand family, in osteoclast differentiation and function]. (1999) (1)
- Interleukin-lα activates NF-KB in osteoclasts (1995) (1)
- Roles of cathelicidins in inflammation and bone loss (2014) (1)
- Formation of osteoclast-like multinucleated cells is human long-term marrow cultures in controlled by osteotropic hormones (1986) (1)
- [Genomic approaches to bone and joint diseases. Mutations of RANK, OPG and RANKL genes found in humans]. (2008) (1)
- The failure of bone resorption in osteosclerotic () mice is due to a defect in osteoclast progenitors but not in local microenvironment (1992) (1)
- The Molecular Mechanism of Osteoclast Differentiation and Activation (2000) (1)
- Study of risedronate therapy in osteoporotic patients using both electronic monitoring of patient adherence and bone marker data (2009) (1)
- [Origin of osteoclasts and mechanism of the formation]. (1991) (1)
- Prolonged Decrease of Serum Calcium Concentration by Murine 7-Interferon in Hypercalcémie,Human Tumor (EC-GI)-bearing Nude Mice1 (2006) (1)
- RANKL is a therapeutic target of bone destruction in rheumatoid arthritis (2019) (1)
- [Current Topics on Vitamin D. The role of active forms of vitamin D in regulation of bone remodeling]. (2015) (1)
- bone tissue as systemic organ supporting a life - Correlation between periodontitis and osteoporosis : bric-garn-0021 (2014) (0)
- The new mechanism of osteoclast differentiation (2014) (0)
- Osteoclast Cell Lineage (2014) (0)
- from That of Macrophages Response to Lipopolysaccharide Is Different Cytokine Production of Osteoclasts in Osteoclasts Via Toll-Like Receptor 4, but Lipopolysaccharide Promotes the Survival of (2003) (0)
- [Possible role of RANKL in bone resorption]. (2004) (0)
- [Possible roles of TNF family cytokines in bone destruction of rheumatoid arthritis]. (2002) (0)
- Roles of Wnt signals in bone resorption during physiological and pathological states (2012) (0)
- Formation Lipopolysaccharide-Induced Osteoclast Is Crucially Involved in 2 by Prostaglandin E Suppression of Osteoprotegerin Expression (2004) (0)
- Role of p38 MAPK-mediated Signals in Osteoclast Differentiation and Function (アジア地域招聘研究受領報告) (2002) (0)
- The molecular mechanism of inflammatory bone resorption (2000) (0)
- [Mechanism of action of bisphosphonate]. (2003) (0)
- The TREM-2-{beta}-catenin axis is critical to regulate macrophage colony-stimulating factor proliferation and bone homeostasis (2011) (0)
- Platypus and opossum calcitonins exhibit strong activities, even though they belong to mammals. (2017) (0)
- MECHANISMS OF CELL FUSION INDUCED BY 1α,25-DIHYDROXYVITAMIN D3 (1988) (0)
- Recombinant HumanTransforming GrowthFactor-Alpha Stimulates the Formation ofOsteoclast-like Cells inLong-term HumanMarrowCultures (1986) (0)
- Clinical pharmacology of drug for treatment of osteoporosis. Bone resorption depressant. Action mechanism of bis-phosphonate and calcitonin. (1996) (0)
- Osteoclast survival is enhanced by p38 MAPK signaling(Oral Session,The 16th Annual Meeting of the Society for Hard Tissue Regenerative Biology in Matsumoto Dental University) (2007) (0)
- [Regulatory mechanism of osteoclast differentiation and function]. (2004) (0)
- Vitamin D in The Regulation of Osteoclasts (2020) (0)
- Interleukin ( IL )-6 Induc t ion o f Osteoclast Dif ferent iat (2003) (0)
- Control mechanism of bone formation and resorption. (1989) (0)
- [Frontiers in vitamin D; basic research and clinical application. Inhibitory effects of eldecalcitol, an active vitamin D derivative, on bone resorption in vivo]. (2011) (0)
- Isolation and characterization of osteoclast precursors in vivo (2010) (0)
- Effects of muramyl dipeptide on osteoclast formation induced by LPS, IL-1 and TNF-α in mouse culture system (2005) (0)
- Identification of osteoclasts in culture. (2011) (0)
- Cell-like Cells Progenitor Cells To Produce Dendritic Osteoclastic-Differentiation Pathway of Tetracyclines Convert the (0)
- Osteoclast Differentiation and Function Multifunctional Regulator in Murine Osteoclast Differentiation Factor Acts as a (1999) (0)
- The mechanism of action, metabolism and distribution of 1α-hydroxycholecalciferol in bone (1992) (0)
- Local production of 1α, 25-dihydroxyvitamin D3 from 1α-hydroxyvitamin D3 in bone (1992) (0)
- Murine osteoclasts secrete serine protease HtrA1 capable of degrading osteoprotegerin in the bone microenvironment (2019) (0)
- This information is current as from Osteoblasts B Ligand Derived κ Receptor Activator of NF-Osteoprotegerin Reduces the Serum Level of Penninger and Naoyuki Takahashi (2006) (0)
- How Does Vitamin D Regulate Osteoclastic Bone Resorption (2019) (0)
- Cell Cycle-Arrested Osteoclast Precursors (2010) (0)
- The TREM-2-β-catenin axis is critical to regulate macrophage colony-stimulating factor proliferation and bone homeostasis (153.29) (2011) (0)
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What Schools Are Affiliated With Naoyuki Takahashi?
Naoyuki Takahashi is affiliated with the following schools:
