Nathan O. Kaplan

Q: What Schools Are Affiliated With Nathan O. Kaplan

Nathan O. Kaplan is affiliated with the following schools: Washington University in St. Louis, University of California, Berkeley, University of California, San Diego, Wayne State University, University of California, Los Angeles, Stanford University, Johns Hopkins University, University of Illinois Urbana-Champaign, Brandeis University

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Nathan O. Kaplan

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According to Wikipedia, Nathan Oram Kaplan was an American biochemist who studied enzymology and chemotherapy. Biography After completing a B.A. in chemistry at UCLA in 1939, Kaplan studied carbohydrate metabolism in the liver under David M. Greenberg at the University of California, Berkeley medical school. He earned his Ph.D. in 1943. From 1942 to 1944, Kaplan participated in the Manhattan Project, and then spent a year as an instructor at Wayne State University. From 1945 to 1949, Kaplan worked with Fritz Lipmann, G. David Novelli, and Beverly Guirard to study coenzyme A. Kaplan went to the University of Illinois College of Medicine as an assistant professor in 1949, and from 1950 to 1957 he worked at the McCollum-Pratt Institute of Johns Hopkins University. In 1957, he was recruited to head a new graduate program in biochemistry at Brandeis University. In 1968, Kaplan moved to the University of California, San Diego, where he studied the role of lactate dehydrogenase in cancer. He also founded a colony of nude mice, a strain of laboratory mice useful in the study of cancer and other diseases. In 1981, Kaplan became a founding member of the World Cultural Council.

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Nathan O. Kaplan's Published Works

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Published Works

Methods in Enzymology , Vol (1966) (26110)
Nature and Development of Lactic Dehydrogenases: The two major types of this enzyme form molecular hybrids which change in makeup during development. (1962) (836)
Lactic Dehydrogenases: Functions of the Two Types (1964) (489)
LACTIC DEHYDROGENASE IN HUMAN NEOPLASTIC TISSUES. (1964) (368)
THE COMPARATIVE ENZYMOLOGY OF LACTIC DEHYDROGENASES. I. PROPERTIES OF THE CRYSTALLINE BEEF AND CHICKEN ENZYMES. (1964) (310)
The comparative enzymology of creatine kinases. I. Isolation and characterization from chicken and rabbit tissues. (1967) (269)
The reaction of pyridine nucleotide with cyanide and its analytical use. (1951) (268)
The comparative enzymology of lactic dehydrogenases. 3. Properties of the H4 and M4 enzymes from a number of vertebrates. (1967) (228)
Developmental Changes of Mammalian Lactic Dehydrogenases (1963) (228)
Molecular heterogeneity and evolution of enzymes. (1960) (219)
Creatine kinase: evidence for a dimeric structure. (1965) (192)
Hydrogen evolution by a chloroplast-ferredoxin-hydrogenase system. (1973) (192)
Structure-function relationships in lactate dehydrogenase. (1973) (184)
Inhibition of spleen diphosphopyridine nucleotidase by nicotinamide, an exchange reaction. (1953) (175)
Functions of the Two Forms of Lactic Dehydrogenase in the Breast Muscle of Birds (1963) (170)
Reaction of pyridine nucleotide analogues with dehydrogenases. (1956) (165)
EVOLUTION AND DIFFERENTIATION OF DEHYDROGENASES * (1961) (165)
Kinetics of Escherichia coli B D-lactate dehydrogenase and evidence for pyruvate-controlled change in conformation. (1968) (165)
THE COMPARATIVE ENZYMOLOGY OF TRIOSEPHOSPHATE DEHYDROGENASE. (1964) (163)
Starch-gel electrophoresis of malate dehydrogenase. (1963) (158)
Pyridine nucleotide transhydrogenase. III. Animal tissue transhydrogenases. (1953) (153)
Pyridine nucleotide synthesis in the mouse. (1956) (153)
Effect of alkali on diphosphopyridine nucleotide. (1951) (147)
Purification and Properties of Chicken Heart Mitochondrial and Supernatant Malic Dehydrogenases (1966) (143)
SIGNIFICANCE OF SUBSTRATE INHIBITION OF DEHYDROGENASES * (1968) (142)
Chemical characterization of D-lactate dehydrogenase from Escherichia coli B. (1968) (135)
The comparative enzymology of creatine kinases. II. Physical and chemical properties. (1967) (135)
Chemistry and properties of the 3-acetylpyridine analogue of diphosphopyridine nucleotide. (1956) (131)
Coenzyme for acetylation, a pantothenic acid derivative. (1947) (130)
Fluorescence of Pyridine Nucleotides in Mitochondria (1962) (129)
Monoclonal antibody and an antibody-toxin conjugate to a cell surface proteoglycan of melanoma cells suppress in vivo tumor growth. (1983) (118)
D- and L-lactic acid dehydrogenases in Lactobacillus plantarum. (1960) (116)
EVOLUTION OF LACTIC DEHYDROGENASES. (1964) (116)
Neurospora diphosphopyridine nucleotidase. (1951) (114)
An acid phosphatase in the plasma membranes of human astrocytoma showing marked specificity toward phosphotyrosine protein. (1982) (113)
Methods in enzymology (1955) (111)
Antineoplastic activity of poly(L-lysine) with some ascites tumor cells. (1979) (108)
Enzymatically active conformers of mitochondrial malate dehydrogenase. (1966) (108)
NATURE OF MULTIPLE MOLECULAR FORMS OF ENZYMES * (1968) (108)
[128] Procedures for determination of pyridine nucleotides (1957) (103)
Effect of isonicotinic acid hydrazide on diphosphopyridine nucleotidases. (1954) (102)
Pyridine nucleotide transhydrogenase. I. Indirect evidence for the reaction and purification of the enzyme. (1952) (101)
Malate dehydrogenases. I. A survey of molecular size measured by gel filtration. (1967) (100)
Changes in enzymatic constitution in zinc-deficient Neurospora. (1951) (99)
Physicochemical properties of pig and horse heart mitochondrial malate dehydrogenase. (1963) (98)
Reversible inactivation of dehydrogenases. (1966) (93)
The isolation and properties of the isonicotinic acid hydrazide analogue of diphosphopyridine nucleotide. (1954) (92)
Immobilization of hydrogenase on glass beads. (1976) (92)
Pyridine nucleotide transhydrogenase. VII. Determination of the reactions with coenzyme analogues in mammalian tissues. (1959) (91)
Enzymatic studies with analogues of diphosphopyridine nucleotide. (1959) (90)
D-Lactate Specific Pyridine Nucleotide Lactate Dehydrogenase in Animals (1968) (90)
Malate dehydrogenases. II. Purification and properties of Bacillus subtilis, Bacillus stearothermophilus, and Escherichia coli malate dehydrogenases. (1967) (89)
Studies on the Mechanism of Hybridization of Lactic Dehydrogenases in Vitro (1965) (88)
Control of synthesis of lactic acid dehydrogenases. (1966) (87)
EFFECTS OF HORMONE ADMINISTRATION ON LACTIC DEHYDROGENASE. (1964) (84)
EFFECTS OF FREEZING ON ENZYMES. (1965) (83)
PHOSPHORYLATIVE AND NONPHOSPHORYLATIVE PATHWAYS OF ELECTRON TRANSFER IN RAT LIVER MITOCHONDRIA. (1956) (83)
Enzyme stereospecificities for nicotinamide nucleotides (1978) (82)
The comparative enzymology of lactic dehydrogenases. IV. Function of sulfhydryl groups in lactic dehydrogenases and the sequence around the essential group. (1965) (82)
A specific b nucleotidase. (1953) (81)
8-(6-Aminohexyl)-amino-adenine nucleotide derivatives for affinity chromatography. (1974) (80)
Kinases for the synthesis of coenzyme A and triphosphopyridine nucleotide. (1954) (79)
Lactic dehydrogenases and muscular dystrophy in the chicken. (1962) (79)
Significance of Enzymatically Catalyzed Exchange Reactions in Chemotherapy (1954) (77)
Inhibition of dehydrogenase reactions by a substance formed from reduced diphosphopyridine nucleotide. (1961) (77)
THE COMPARATIVE ENZYMOLOGY OF LACTIC DEHYDROGENASES. II. PROPERTIES OF THE CRYSTALLINE HM3 HYBRID FROM CHICKEN MUSCLE AND OF H2M2 HYBRID AND H4 ENZYME FROM CHICKEN LIVER. (1964) (77)
Determination of the hydride transfer stereospecificity of nicotinamide adenine dinucleotide linked oxidoreductases by proton magnetic resonance. (1976) (76)
Addition products of diphosphopyridine nucleotides with substrates of pyridine nucleotide-linked dehydrogenases (1971) (76)
Pyridine nucleotide transhydrogenase. II. Direct evidence for and mechanism of the transhydrogenase reaction. (1952) (74)
Purification and properties of two types of diphosphopyridine nucleotide-linked glycerol 3-phosphate dehydrogenases from chicken breast muscle and chicken liver. (1969) (74)
The activity of the acidic phosphoproteins from the 80 S rat liver ribosome. (1982) (73)
PHOSPHOROLYSIS AND SYNTHESIS OF SUCROSE WITH A BACTERIAL PREPARATION (1943) (73)
Lactate dehydrogenase of lobster (Homarus americanus) tail muscle. I. Physical and chemical properties. (1969) (73)
Characteristics of 8-substituted adenine nucleotide derivatives utilized in affinity chromatography. (1975) (71)
A COMMON FACTOR IN THE ENZYMATIC ACETYLATION OF SULFANILAMIDE AND OF CHOLINE (1946) (70)
The liberation of pantothenic acid from coenzyme A. (1949) (70)
Comparison of diphosphopyridine nucleotide with its deaminated derivative in various enzyme systems. (1952) (69)
The formation of ternary complexes by diphosphopyridine nucleotide-dependent dehydrogenases. (1971) (68)
A structure of pyridine nucleotides in solution. (1971) (68)
STRUCTURAL AND FUNCTIONAL PROPERTIES OF THE H AND M SUBUNITS OF LACTIC DEHYDROGENASES * (1965) (67)
The preparation and properties of N-hydroxyethyl derivatives of adenosine, adenosine triphosphate, and nicotinamide adenine dinucleotide. (1961) (67)
Purification and kinetic characteristics of dogfish liver glutamate dehydrogenase. (1967) (67)
New doxorubicin analogs active against doxorubicin-resistant colon tumor xenografts in the nude mouse. (1980) (66)
Effects of oxygen, iron, and molybdenum on routes of electron transfer in Pseudomonas fluorescens. (1956) (66)
Chemical properties of 3-substituted pyridine analogues of diphosphopyridine nucleotide. (1959) (65)
A lactate dehydeogenase specific to the liver of gadoid fish. (1972) (65)
Investigations of inter- and intramolecular interations in flavin--adenine dinucleotide by proton magnetic resonance. (1968) (64)
31P nuclear magnetic resonance studies of HeLa cells. (1977) (64)
Enzymatic deamination of adenosine derivatives. (1952) (63)
DISTRIBUTION OF ENZYMES CLEAVING PYRIDINE NUCLEOTIDES IN ANIMAL TISSUES (1957) (63)
LACTIC DEHYDROGENASES: FUNCTIONS OF THE TWO TYPES RATES OF SYNTHESIS OF THE TWO MAJOR FORMS CAN BE CORRELATED WITH METABOLIC DIFFERENTIATION. (1964) (63)
Evolution of Creatine Kinase (1967) (62)
Structure of the primary acid rearrangement product of reduced nicotinamide adenine dinucleotide (NADH). (1974) (62)
Isolation of coenzyme A. (1950) (61)
Association by hydrogen bonding of mononucleotides in aqueous solution. (1972) (59)
Characteristics of arthropod arginine kinases. (1968) (59)
Role of the two types of lactic dehydrogenase. (1964) (59)
Investigation of the conformation of beta-diphosphopyridine nucleotide (beta-nicotinamide-adenine dinucleotide) and pyridine dinucleotide analogs by proton magnetic resonance. (1968) (59)
[69] Specific adenosine deaminase from intestine (1955) (57)
On the tissue specificity and biological significance of aldolase C in the chicken. (1967) (56)
HEXITOL DEHYDROGENASES OF BACILLUS SUBTILIS. (1964) (56)
A Cytochrome Peroxidase from Pseudomonas fluorescens (1953) (55)
EVIDENCE FOR TWO FORMS OF M-TYPE LACTATE DEHYDROGENASE IN THE MOUSE. (1963) (54)
Significance of heat-activated enzymes. (1956) (54)
THE DENATURATION OF LACTIC DEHYDROGENASES. I. THE EFFECT OF SODIUM DODECYL SULFATE. (1964) (53)
FACTORS INFLUENCING THE CONCENTRATION OF ENZYMES IN VARIOUS MUSCLES. (1965) (53)
D-Mannitol 1-phosphate dehydrogenase and D-sorbitol 6-phosphate dehydrogenase in Aerobacter aerogenes. (1962) (53)
Biologically active catecholamines covalentyly bound to glass beads. (1972) (53)
Physiological Concentrations of Lactate Dehydrogenases and Substrate Inhibition (1970) (52)
[113] Animal tissue DPNase (pyridine transglycosidase) (1955) (52)
THE 3-ACETYLPYRIDINE ANALOG OF DPN1 (1954) (50)
Structural characteristics of dehydrogenases. (1962) (50)
Diphosphopyridine nucleotide-linked D-lactate dehydrogenases from the horseshoe crab, Limulus polyphemus and the seaworm, Nereis virens. I. Physical and chemical properties. (1973) (49)
I. MULTIPLE FORMS OF ENZYMES (1963) (49)
The enzyme-coenzyme-substrate complexes of pyridine nucleotide dependent dehydrogenases. (1958) (49)
Hybridization of Lactic Dehydrogenase in vivo and in vitro (1965) (49)
Creatine kinase isozymes in human tumors. (1981) (48)
IMMUNOLOGICAL CHARACTERISTICS OF DEHYDROGENASES (1963) (47)
ISOLATION OF A DPN ISOMER CONTAINING NICOTINAMIDE RIBOSIDE IN THE α LINKAGE1 (1955) (47)
Yeast Alcohol Dehydrogenase. III. Relation of Alcohol Structure to Activity1 (1957) (47)
3-Acetylpyridine: Effects in vitro Related to Teratogenic Activity in Chicken Embryos (1968) (47)
Formation of the nicotinic acid analogue of diphosphopyridine nucleotide after nicotinamide administration. (1959) (46)
Pyridine nucleotide transhydrogenase. IV. Effect of adenylic acid a on the bacterial transhydrogenases. (1953) (46)
The effect of pantothenic acid deficiency upon the coenzyme A content and pyruvate utilization of rat and duck tissues. (1948) (46)
Purification and properties of the pyridine nucleotide transhydrogenase from Pseudomonas aeruginosa. (1970) (46)
Yeasl alcohol dehydrogenase. I. The effect of pyridine derivatives on the reaction. (1957) (46)
Glyceraldehyde-3-phosphate dehydrogenase catalyzed hydration of the 5-6 double bond of reduced beta-nicotinamide adenine dinucleotide (betaNADH). Formation of beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide. (1974) (46)
THE ROLE OF THE SULFHYDRYL GROUPS OF LACTIC DEHYDROGENASES. (1963) (45)
LACTATE DEHYDROGENASE--STRUCTURE AND FUNCTION. (1964) (44)
MECHANISMS OF ACTION AND BIOLOGICAL FUNCTIONS OF VARIOUS DEHYDROGENASE ISOZYMES (1975) (44)
Lectins from chicken tissues are mitogenic for Thy-1 negative murine spleen cells. (1980) (44)
SUBSTITUTED NICOTINAMIDE ANALOGUES OF NICOTINAMIDE ADENINE DINUCLEOTIDE. (1963) (43)
The nicotinic acid analogue of diphosphopyridine nucleotide. (1958) (43)
The involvement of pyridine nucleotide transhydrogenase in ATP-linked TPN reduction by DPNH (1964) (43)
8-Alkylaminoadenyl nucleotides as probes of dehydrogenase interactions with nucleotide analogs of different glycosyl conformation. (1976) (43)
The reaction of pyridine nucleotides with carbonyl compounds. (1954) (43)
Factors affecting the reversible dissociation of dehydrogenases. (1965) (43)
The disulfide bond connecting the chains of ricin. (1978) (42)
Chicken heart soluble aspartate aminotransferase. Purification and properties. (1968) (42)
Therapeutic response of human tumor xenografts in athymic mice to doxorubicin. (1981) (42)
Effect of adenine nucleotides on reactions involving triphosphopyridine nucleotide. (1955) (42)
Identification of lactate dehydrogenase isoenzymes by rapid kinetics. (1972) (42)
IMMUNOLOGY AND RATES OF ENZYME EVOLUTION IN THE AMPHIBIA IN RELATION TO THE ORIGINS OF CERTAIN TAXA (1966) (41)
A reduced pyridine nucleotide pyrophosphatase. (1957) (41)
The reaction of reduced pyridine nucleotides with acid. (1963) (41)
The antileukemic action of two thiadiazole derivatives. (1960) (41)
Diphosphopyridine nucleotide-linked D-lactate dehydrogenases from the horseshoe crab, Limulus polyphemus, and the seaworm, Nereis virens. II. Catalytic properties. (1973) (41)
Purification and separation of pyridine nucleotide-linked dehydrogenases by affinity chromatography techniques. (1974) (40)
Purification and properties of a DPNH-TPNH diaphorase from Clostridium kluyverii. (1969) (40)
HEXITOL METABOLISM IN ESCHERICHIA COLI (1956) (39)
Immobilized enzymes: the catalytic properties of lactate dehydrogenase convalently attached to glass beads. (1973) (39)
Evolution of Dehydrogenases (1965) (39)
Stereospecificity of the intramolecular association of reduced pyridine coenzymes. (1978) (38)
The structure of the abortive diphosphopyridine nucleotide-pyruvate-lactate dehydrogenase ternary complex as determined by proton magnetic resonance analysis. (1974) (38)
Flavin adenine dinucleotide synthesis in animal tissues. (1958) (38)
Induction of sarcomas in athymic mice. (1982) (38)
Pyridine nucleotide transhydrogenase. VIII. Properties of the transhydrogenase reactions of an enzyme complex isolated from beef heart mitochondria. (1961) (37)
Pyridine nucleotide transhydrogenase. VI. Mechanism and stereospecificity of the reaction in Pseudomonas fluorescens. (1955) (37)
A rationale for stabilization of oxygen-labile enzymes: application to a clostridial hydrogenase. (1978) (37)
Kinetics of protein synthesis inactivation in human T-lymphocytes by selective monoclonal antibody-ricin conjugates. (1985) (37)
Kinetic studies of dogfish liver glutamate dehydrogenase with diphosphopyridine nucleotide and the effect of added salts. (1967) (37)
High frequency nuclear magnetic resonance study of the M and P helices of reduced pyridine dinucleotides. (1970) (36)
Purification, properties, and kinetic mechanism of coenzyme A-linked aldehyde dehydrogenase from Clostridium kluyveri. (1980) (36)
Direct evidence for a diphosphopyridine nucleotide-hydroxylamine complex with horse liver alcohol dehydrogenase. (1954) (35)
A DPN SPECIFIC GLYCEROL DEHYDROGENASE FROM AEROBACTER AEROGENES1 (1953) (35)
Solubilization and comparative properties of some mammalian diphosphopyridine nucleosidases. (1967) (35)
Measurements of Enzymes in the Diagnosis of Acute Myocardial Infarction (1961) (35)
Allosteric effect of 2'-adenylic acid on the Pseudomonas pyridine nucleotide transhydrogenase. (1972) (35)
Regulatory characteristics of lactate dehydrogenases. (1972) (34)
The alpha beta epimerization of reduced nicotinamide adenine dinucleotide. (1975) (34)
[57] Beef heart TPNH-DPN pyridine nucleotide transhydrogenases (1967) (34)
A specific spectrophotometric assay for flavin adenine dinucleotide. (1956) (34)
Multiple forms of mitochondrial malate dehydrogenases. (1966) (34)
Purification of arginine kinase from lobster and a study of some factors affecting its reactivation. (1967) (34)
[45] Enzymatic determination of ethanol (1957) (33)
Mechanism of depletion of mitochondrial pyridine nucleotides. (1960) (33)
Chemotherapy of human colorectal tumor xenografts in athymic mice with clinically active drugs: 5‐fluorouracile and 1‐3‐bis‐(‐2‐chloroethyl)‐1‐nitrosourea (bcnu). Comparison with doxorubicin derivatives: 4′deoxydoxorubicin and 4′‐0‐methyldoxorubicin (1981) (32)
A heat-activated diphosphopyridine nucleotide pyrophosphatase from Proteus vulgaris. (1958) (32)
Preparation and properties of some nicotinamide adenine dinucleotide analogues with pentose and purine modifications. (1962) (31)
Effect of reserpine and promazine on diphosphopyridine nucleotide synthesis in liver. (1958) (31)
Solubilization and purification of diphosphopyridine nucleotidase from pig brain. (1962) (31)
Studies on malate dehydrogenases and aspartate aminotransferases from Neurospora crassa. (1967) (30)
Relationship of Structure to Properties of Diphosphopyridine Nucleotide and Other Pyridinium Compounds1 (1957) (30)
Preparation of pyridine nucleotide analogs by the carbonyl addition reaction. (1957) (30)
The reaction of diphosphopyridine nucleotide and related pyridinium salts with alkali. (1963) (30)
THE SULFHYDRYL CONTENT OF SOME LACTATE DEHYDROGENASES. (1963) (30)
Stereospecificity of hydrogen transfer reactions of the Pseudomonas aeruginosa pyridine nucleotide transhydrogenase. (1970) (29)
Competitive inhibition of hydroxylamine on alcohol dehydrogenase. (1953) (29)
Malate dehydrogenases. I. (1967) (29)
High frequency nuclear magnetic resonance investigation of the backbone of oxidized and reduced pyridine nucleotides. (1970) (29)
STUDIES OF PROTEIN AND BOUND COENZYME FLUORESCENCE OF LACTATE DEHYDROGENASES. (1964) (29)
The reduction of inorganic iron and cytochrome c by flavin enzymes. (1956) (29)
Fluorescence studies of coenzyme-binding to beef heart lactic dehydrogenase. (1959) (29)
Metabolites of nicotinamide in mouse urine. Effects of azaserine. (1961) (28)
Aminoacid sequence of dogfish M4 lactate dehydrogenase. (1973) (27)
Physical and chemical properties of lactate dehydrogenase in Homarus americanus. (1977) (27)
Mitochondrial malate dehydrogenase: further studies on multiple electrophoretic forms. (1970) (27)
HYBRIDIZATION OF LACTIC DEHYDROGENASES IN VITRO BY CONCENTRATED SODIUM CHLORIDE AND BY REVERSIBLE INACTIVATION IN UREA. (1964) (27)
Yeast alcohol dehydrogenase. IV. Coenzyme binding sites. (1958) (27)
The subunits of dogfish M4 lactic dehydrogenase. (1969) (27)
Induction of lymphoma in antigenically stimulated athymic mice. (1982) (27)
Effect of hormones and environmental factors on lactic dehydrogenases. (1965) (26)
[129] Preparation of DPN derivatives and analogs (1957) (26)
Yeast alcohol dehydrogenase. II. Properties of the catalytically active site. (1957) (26)
Studies on the conformations of the multiple forms of chicken heart aspartate aminotransferase. (1970) (26)
Studies on the mitochondrial energy-linked pyridine nucleotide transhydrogenase. (1973) (26)
Induction of T- and B-lymphocyte responses in antigenically stimulated athymic mice. (1981) (26)
Immobilized catecholamine and cocaine effects on contractility of cardiac muscle. (1973) (26)
Streptozotocin-induced Diabetes in Athymic and Conventional BALB/c MICE (1980) (26)
Effect of 4'-doxorubicin analogs on heterotransplantation of human tumors in congenitally athymic mice. (1981) (26)
STUDIES WITH RADIOACTIVE PHOSPHORUS OF THE CHANGES IN THE ACID-SOLUBLE PHOSPHATES IN THE LIVER COINCIDENT TO ALTERATIONS IN CARBOHYDRATE METABOLISM II. THE EFFECT OF GLUCOSE, INSULIN, AND OF CERTAIN METABOLIC INHIBITORS (1944) (26)
Induction of lymphoma in athymic mice: a model for study of the human disease. (1980) (25)
The monoester phosphate grouping of coenzyme A. (1954) (25)
Pyridine precursors of mouse liver diphosphopyridine nucleotide. (1957) (25)
D-Mannitol 1-phosphate dehydrogenase from Escherichia coli. (1956) (25)
Purification of kinases by general ligand affinity chromatography. (1977) (25)
Pyridine nucleotide transhydrogenase in normal human and leukemic leukocytes. (1966) (25)
Purification and characterization of diphosphopyridine nucleosidase from pig brain. (1967) (25)
The reactivity of the bound DPN of muscle triose phosphate dehydrogenase. (1957) (25)
Physical and chemical properties of reversibly inactivated lactate dehydrogenases. (1971) (25)
Biological activity of catecholamines covalently linked to synthetic polymers: proof of immobilized drug theory. (1976) (24)
Nicotinamide riboside phosphorylase from human erythrocytes. II. Nicotinamide sensitivity. (1958) (24)
Effect of azaserine on the biosynthesis of diphosphopyridine nucleotide in mouse. (1961) (24)
Purification and properties of malate dehydrogenase from Pseudomonas testosteroni (1975) (24)
STRUCTURAL AND CATALYTIC ALTERATIONS OF DEHYDROGENASES AFTER PHOTOOXIDATION. (1963) (24)
Studies on the interaction of diphosphopyridine nucleotide analogs with dehydrogenases. (1957) (24)
Intramolecular hydrogen bonding in flavin adenine dinucleotide. (1974) (23)
Effect of Azaserine (o-Diazoacetyl-L- serine) on the Pyridine Nucleotide Levels of Mouse Liver (1959) (23)
Catalytic properties of lactate dehydrogenase in Homarus americanus. (1977) (22)
Lactate dehydrogenase of lobster (Homarus americanus) tail muscle. II. Kinetics and regulatory properties. (1969) (22)
Structure of Dihydrodiphosphopyridine Nucleotide (1959) (22)
Investigation of the configuration and conformation of N-methyl-N-ethylnicotinamide-adenine dinucleotide by nuclear magnetic resonance spectroscopy. (1970) (22)
Purification and substrate specificities of bacterial hydroxysteroid dehydrogenases. (1969) (22)
220 MHz nuclear magnetic resonance spectra of oxidized and reduced pyridine dinucleotides. (1969) (22)
Pyridine nucleotide transhydrogenase. V. Exchange reactions studied with C14. (1953) (22)
Kinetic characteristics of the pyridine nucleotide transhydrogenase from Pseudomonas aeruginosa. (1970) (22)
THE DENATURATION OF LACTIC DEHYDROGENASES. II. THE EFFECT OF UREA AND SALTS. (1965) (22)
Pyridine nucleotide transhydrogenases. (1971) (22)
FORMATION OF THE ISONICOTINIC ACID HYDRAZIDE ANALOG OF DPN1 (1953) (21)
Proton magnetic resonance study of the intramolecular association and conformation of the alpha and beta pyridine mononucleotides and nucleosides. (1976) (21)
Interacting binding sites of L-specific lactic dehydrogenase of Escherichia coli. (1965) (21)
Flavoprotein-catalyzed pyridine nucleotide transfer reactions. (1957) (21)
220 MHz proton nuclear magnetic resonance study of the geometric disposition of the base pairs in the oxidized and reduced pyridine nucleotides. (1969) (21)
Lack of detectable change in cyclic AMP during the cardiac inotropic response to isoproterenol immobilized on glass beads. (1975) (21)
Pyridine nucleotide transhydrogenase from Pseudomonas aeruginosa: purification by affinity chromatography and physicochemical properties. (1976) (21)
The stereospecificity of bacterial external flavoprotein monooxygenases for nicotinamide adenine dinucleotide. (1977) (20)
Isolation and characterization of plasma membranes from transplantable human astrocytoma, oat cell carcinoma, and melanomas. (1981) (20)
A chemical reaction of hydroxylamine with diphospyridine nucleotide. (1954) (20)
ALTERATIONS OF TISSUE LACTATE DEHYDROGENASE IN HUMAN NEOPLASMS. (1963) (20)
The role of pyridine nucleotides in regulating cellular metabolism. (1985) (20)
THE action of ricin A-chain on ribosomes. (1982) (20)
Probing the sensitivity of 31P NMR chemical shifts to hydrogen bonding and to stereochemistry (1979) (19)
The pyridine nucleosidases from Bacillus subtilis and Neurospora crassa. Isolation and structural properties. (1975) (19)
General Ligand Affinity Chromatography in Enzyme Purification Ligands, Affinity Chromatography, Enzyme Purification (1976) (19)
Ternary Systems. XXII. Formation of Solid Solutions from Alums (1938) (19)
Enzymatic preparation of triphosphopyridine nucleotide from diphosphopyridine nucleotide. (1954) (19)
Highly efficient induction of type C retroviruses by a human tumor in athymic mice. (1980) (19)
Determination of the activity and concentration of immobilized and soluble enzymes by microcalorimetry. (1976) (19)
Further studies of nutritional conditions affecting enzymatic constitution in Neurospora. (1953) (19)
PASSIVE TRANSFER OF LYMPHOCYTES FROM DIABETIC MAN TO ATHYMIC MOUSE (1979) (18)
A Mechanism for Pyridine-Nucleotide-Dependent Dehydrogenases (1958) (18)
LACTIC ACID RACEMIZATION * † (1965) (18)
Heterogeneity of the lactic dehydrogenases of new-born and adult rat heart as determined with coenzyme analogs. (1961) (18)
METABOLISM IN DIABETIC COMA PRODUCED BY ALLOXAN (1945) (18)
Intermediary Metabolism of Phosphorus Compounds (1949) (18)
Radioactive phosphate as an indicator of the relationship between the phosphate changes of blood, muscle and liver, following the administration of insulin. (1944) (17)
[14] Enzymatic determination of free sugars (1957) (17)
NATURE OF MONOESTER PHOSPHATE GROUP IN COENZYME A1 (1952) (17)
Salt-induced alteration of D(-) lactate dehydrogenase from Polyspondylium pallidum. (1967) (17)
Significance of Induced In Vivo Synthesis of Diphosphopyridine Nucleotide (1958) (17)
Affinity isolation of cultured tumor cells by means of drugs and hormones covalently bound to glass and Sepharose beads. (1976) (17)
LACTIC ACID RACEMIZATION IN CLOSTRIDIUM BUTYLICUM. (1963) (17)
Characteristics of microbial diphosphopyridine nucleotidases containing exceptionally large amounts of polysaccharides. (1968) (17)
The formation of a ternary complex between diphtheria toxin, aminoacyltransferase II, and diphosphopyridine nucleotide. (1970) (17)
Nicotinamide riboside phosphorylase from human erythrocytes. I. Phosphorolytic activity. (1958) (17)
[34] Preparation and analysis of labeled coenzymes (1957) (16)
Incorporation of Isotopically Labeled Precursors into the Pyridine Nucleotide Coenzymes (1961) (16)
The conversion of pyridine hydroxamic acids to amides by mouse liver mitochondria. (1961) (16)
A possible role for glass bead immobilized enzymes as therapeutic agents (immobilized uricase as enzyme therapy for hyperuricemia). (1975) (16)
Demonstration of separate phosphotyrosyl- and phosphoseryl- histone phosphatase activities in the plasma membranes of a human astrocytoma. (1985) (16)
The action of hydroxylamine and cyanide on alcohol dehydrogenase of horse liver. (1954) (16)
Toxicity and antileukemic effectiveness of pyridine derivatives and 1,3,4-thiadiazole derivatives in mice. Relationship to nicotinamide antagonism. (1962) (15)
The preparation and properties of 3'-triphosphopyridine nucleotide. (1955) (15)
Malate dehydrogenases. 3. Alteration of catalytic properties during purification of Bacillus subtilis malate dehydrogenases. (1967) (15)
[119] Pyridine nucleotide transhydrogenase: (1955) (15)
Chelating agents protect hydrogenase against oxygen inactivation. (1979) (15)
Determination of the absolute stereospecificity of the enzymatic reduction of NAD+ analogs by means of the primary acid cyclization reaction (1974) (15)
Immobilized enzymes in biochemical analysis. (1979) (15)
Thermal stabilities of membrane-bound, solubilized, and artificially immobilized hydrogenase from Chromatium vinosum. (1980) (15)
The role of ethanol extractable proteins from the 80S rat liver ribosome. (1980) (15)
EFFECT OF TETRATHIONATE ON THE STABILITY AND IMMUNOLOGICAL PROPERTIES OF MUSCLE TRIOSEPHOSPHATE DEHYDROGENASES. (1964) (14)
The effect of proteolysis and urea treatment on coenzyme binding to beef-heart lactic dehydrogenase (1961) (14)
Immobilized Lactate Dehydrogenases (1974) (14)
The acetyl precursor in pyruvate synthesis in Escherichia coli. (1948) (14)
Pig-spleen pyridine transglycosidase. I. Purification and properties. (1962) (14)
Mechanism of flavoprotein-catalyzed pyridine nucleotide transfer reactions. (1957) (14)
Current aspects of biochemical energetics : Fritz Lipmann dedicatory volume (1966) (14)
Oxidative phosphorylation and ATPase activities of human tumor mitochondria. (1980) (14)
Reduced nicotinamide 8-(alkylamino)adenine dinucleotides: enzyme-coenzyme interactions with different adenyl glycosyl bond conformations. (1980) (14)
Interleukin 2 is mitogenic for nu/nu and nu/+ murine spleen cells. (1981) (14)
On the role of the covalent carbohydrate in the action of ricin. (1980) (14)
New instrument for rapid determination of activities of lactate dehydrogenase isoenzymes. (1975) (13)
The reaction of pyridine nucleotides with trifluoroacetic acid anhydride. (1955) (13)
Methods In Enzymology Vol-IV (1957) (13)
Large scale synthesis and purification of flavin adenine dinucleotide. (1956) (13)
An apparatus for the determination of kinetic parameters associated with immobilized enzymes. (1973) (13)
Enzymatic degradation and resynthesis of coenzyme A. (1954) (12)
Interaction of 13C-enriched folate with dihydrofolate reductase studies by carbon magnetic resonance spectroscopy. (1976) (12)
The function of inorganic iron in the reduction of cytochrome C. (1954) (12)
Isoenzymes in Clinical Diagnosis (1965) (12)
Studies with radioactive phosphorus of the changes in the acid-soluble phosphates in the liver coincident to alterations in carbohydrate metabolism. 1. Separation and nature of the organic acid-soluble phosphates of liver. (1944) (12)
Chromatium hydrogenase. (1977) (12)
[86] 3′-Nucleotidase from rye grass: Nucleoside3′P+H2O→ Nucleoside+P (1955) (12)
The diaphorases of rat-liver mitochondria. (1958) (11)
The Influence of Antibody on the Interaction between Nucleotides and Glutamic Dehydrogenase (1965) (11)
Proton nuclear magnetic resonance study of the conformation and configuration of the cyclized pyridine nucleotide adducts. (1979) (11)
The structure and quantitation of catecholamines covalently bound to glass beads. (1975) (11)
Proton magnetic resonance study of 8-(6-aminohexyl)-aminoadenosine 5′-monophosphate (1978) (10)
[70] Nonspecific adenosine deaminase from takadiastase: Adenosine compound H2→Inosine compound+NH3 (1955) (10)
Reaction of thiol compounds with pyridine nucleotides. (1957) (10)
Pyridine coenzymes of subcellular tissue fractions. (1957) (10)
COMPLEXES OF PYRIDINE NUCLEOTIDES AND THEIR FUNCTION (1972) (10)
220 MHz proton nuclear magnetic resonance study of the interaction between chicken M4 lactate dehydrogenase and reduced diphosphopyridine nucleotide. (1970) (10)
The amino acid sequence of the tryptic peptides isolated from dogfish M4 lactate dehydrogenase. (1975) (10)
Variable ATPase composition of human tumor plasma membranes. (1981) (10)
In vitro responses of nude mouse-xenografted human colon carcinomas exposed to doxorubicin derivatives in tissue culture and in the mouse. (1982) (10)
Stability of Catecholamines Immobilized on Glass Beads (1974) (10)
Investigations into the relationship between structure and function of diphtheria toxin. (1977) (10)
Advances in Enzymology and Related Subjects of Biochemistry. (1958) (10)
Chemistry and distribution of the coenzyme for acetylation (coenzyme A). (1947) (10)
Conformations of diphosphopyridine coenzymes upon binding to dehydrogenases. (1973) (10)
From cyclotrons to cytochromes : essays in molecular biology and chemistry (1982) (9)
Revertants of Escherichia coli mutants defective in the cyclic AMP system. (1975) (9)
Symposium on electron transport in the metabolism of microorganisms. (1955) (9)
Accumulation of oxidized diphosphopyridine nucleotide in mouse liver after administration of reduced diphosphopyridine nucleotide. (1970) (9)
Effect of pyridine derivatives on animal tissue diphosphopyridine nucleotidases. (1959) (9)
Pseudomonas aeruginosa transhydrogenase: affinity of substrates for the regulatory site and possible hysteretic behavior. (1977) (9)
A POSSIBLE ENZYMATIC ROLE OF ERGOTHIONEINE1 (1956) (9)
Observations with P32 of the changes in the acid-soluble phosphates in the liver coincident to alterations in carbohydrate metabolism. (1943) (9)
The pyridine nucleosidase from Bacillus subtilis. Kinetic properties and enzyme-inhibitor interactions. (1975) (9)
Regulation of pyridine nucleotide coenzymes. (1968) (8)
Effects of substrates on the swelling and loss of pyridine/nucleotides from rat-liver mitochondria. (1959) (8)
Regulation of lactate dehydrogenase synthesis in Bacillus subtilis. (1978) (8)
Differentiation and activation of nu/nu splenic T cell precursors by mature peripheral T cells in the absence of thymus. (1982) (8)
[123] Preparation of deaminated adenine derivatives (1957) (8)
Diphtheria toxin effects on human cells in tissue culture. (1976) (8)
The action of insulin on the phosphate cycle. (1944) (7)
Enzymatic Identification of Fish Products (1967) (7)
[64] Immobilization of lactic dehydrogenase (1976) (7)
The addition of sulfhydryl compounds to diphosphopyridine nucleotide and its analogues. (1957) (7)
Mechanism of lactic acid oxidation catalyzed by lactate dehydrogenase from the tail muscle of Homarus americanus. (1978) (7)
Studies with radioactive phosphorus of the changes in the acid-soluble phosphates in the liver coincident to alterations in carbohydrate metabolism. 3. The effect of fasting and of high fat, high carbohydrate, and high protein diets. (1944) (7)
Pyridine nucleotide analogs and the sulfhydryl nature of some FAD enzymes. (1956) (7)
[135] Cytochrome c and cytochrome c peroxidase from Pseudomonas fluorescens (1955) (7)
Conformational changes induced in dihydrofolate reductase by folates, pyridine nucleotide coenzymes, and methotrexate. (1974) (7)
Regulation of lactate hydrogen synthesis in Bacillus subtilis (1978) (7)
The synthesis of 8-(6-aminohexyl)-amino-GMP and its applications as a general ligand in affinity chromatography. (1978) (7)
Activation Effect of 2′-Adenylic Acid on Bacterial Transhydrogenases (1970) (6)
Pyridine nucleotides in normal and nicotinamide depleted adrenal tumor cell cultures. (1972) (6)
The hydroxyethylation and subsequent hydrolysis of deoxyguanosine at pH 7 and 25 degree. (1962) (6)
On the mechanism of the transhydrogenase reaction catalyzed by a beef heart flavoprotein (1960) (6)
Plasma membrane-associated phosphatase activities hydrolyzing [32P]phosphotyrosyl histones and [32P]phosphatidylinositol phosphate. (1987) (6)
Screening of new doxorubicin (dx) analogs with activity against human colon carcinoma xenografts. Abstr. (1980) (6)
A comparison of some vicglycol dehydrogenase systems found in Aerobacter aerogenes. (1960) (6)
Enzymic properties of chemically prepared diphosphopyridine nucleotide analogs. (1957) (6)
Studies of bovine liver glutamate dehydrogenase by analytical affinity chromatography on immobilized AMP analogs. (1979) (6)
The effect of electron carriers and other ligands on oxygen stability of clostridial hydrogenase. (1981) (6)
Proton relaxation studies of diphosphopyridine coenzymes. (1974) (6)
Ternary Systems. XXI. Lead Nitrate, Ammonium Nitrate and Water at 25° (1936) (5)
FLUORESCENCE STUDIES OF COENZYME BINDING TO DEHYDROGENASES. (1958) (5)
Report on a coenzyme for acetylation. (1946) (5)
[50] Antiproliferative assay for human interferons (1981) (5)
Characterization of catecholamine-polypeptide conjugates (1983) (5)
The action of nicotinamide and isonicotinic acid hydrazide on diphosphopyridine nucleotidases; a preliminary note. (1952) (5)
Regulatory properties of the pyridine nucleotide transhydrogenase from Pseudomonas aeruginosa. Kinetic studies and fluorescence titration. (1976) (5)
Experiences in Biochemistry (1986) (5)
The isolation and characterization of a 1,2-propanediol oxidoreductase from Neisseria gonorrhoeae. (1980) (5)
Aerobic phosphorylations in tissue slices. (1945) (5)
Iodination of muscle fructose diphosphate aldolase. (1968) (4)
Interaction of nicotinamide with reserpine and chlorpromazine. III. Some effects on the diphosphopyridine nucleotide content in liver. (1960) (4)
UPTAKE OF P32 IN RESTING CELLS OF CLOSTRIDIUM PERFRINGENS (1959) (4)
A cytochrome peroxidase from Pseudomonas fluorescens. (1956) (4)
Agar gel electrophoretic demonstration of charge alteration in mutant bacterial proteins. (1969) (4)
Reactions between acetate, acetyl phosphate and the adenylic acid system in tissue and bacterial extracts. (1948) (4)
Purification of phosphotransacetylase by affinity chromatography. (1979) (4)
Relationship of 3α-Hydroxysteroid Dehydrogenase to Pyridine Nucleotide Transhydrogenases (1959) (4)
[46] Hexose phosphate and hexose reductase: A. d-mannitol-1-phosphate dehydrogenase from E. coli F-6-P + DPNH + H+ ⇄ Mannitol-l-P + DPN+ (1955) (4)
Spurious DNA blot hybridization resulting from bacterial contamination of primary tissue preparations. (1987) (4)
Regulatory properties of the pyridine nucleotide transhydrogenase from Pseudomonas aeruginosa. Active enzyme ultracentrifugation studies. (1976) (4)
The Structure of Pyridine Coenzymes as Related to Binding (1970) (4)
Structural factors in the succinate-induced reduction of mitochondrial pyridine nucleotides. (1963) (3)
Methods in enzymology. Volume V. Preparation and assay of enzymes. (1962) (3)
NEW CONCEPTS OF THE USE OF INHIBITORS IN CHEMOTHERAPY. (1964) (3)
The Use of Athymic Mice in the Screening of New Anthracycline Derivatives (1984) (3)
Mechanisms of electron transport in pyridine nucleotide and flavin systems. (1955) (3)
The role of the reduced diphosphopyridine nucleotide in the reactivation of dogfish muscle lactate dehydrogenase. (1971) (3)
Adaptive formation of a vicglycol dehydrogenase in Aerobacter aerogenes. (1960) (3)
Purification of Dehydrogenases and Kinases by Affinity Chromatography (1978) (2)
Metabolism in diabetic coma produced by alloxan. (1945) (2)
Immobilization of lactic dehydrogenase. (1976) (2)
HISTORICAL PERSPECTIVES OF PURIFICATION OF BIOMOLECULES (1983) (2)
A partial purification of the beta-adrenergic receptor adenylate cyclase complex by affinity chromatography to glass bead-immobilized isoproterenol. (1974) (2)
Sidney P. Colowick. (1985) (2)
Letter: Stability of catecholamines immobilized on glass beads. (1974) (2)
Methods in enzymology. Volume VI. Preparation and assay of enzymes (continued). Preparation and assay of substrates. Special techniques. (1963) (2)
Effect of Starvation and Ageing on the Acid-Soluble Phosphate Components of the Liver (1944) (2)
Preface to volumes V and VI (1962) (2)
Amplification of the murine leukemia virus Mr 70,000 glycoprotein gene product by human xenografts in athymic mice. (1983) (2)
Approaches to stabilization of hydrogenase and nitrogenase against oxygen inactivation (1980) (2)
Therapeutic synergism of 5-fu and 4'deoxydoxorubicin (deodx) com- bination chemotherapy in human colorectal tumors xenografted into athymic mice. Abstr. (1981) (1)
Development of transplantable human tumors in nude mice. Abstr. (1977) (1)
Antiproliferative assay for human interferons. (1981) (1)
Discussion: Part IV (1984) (1)
LACTIC DEHYDROGENASE IN CANCER. (1964) (1)
The mechanism of enzymatic acetylation. (1947) (1)
A leukemia virus-related protein in the murine pancreas. (1984) (1)
The synthesis of 8-(6-aminohexyl)-amino-GTP and -GDP and their application as ligands in affinity chromatography. (1979) (1)
Methods in enzymology. Volume IV. Special techniques for the enzymologist. (1957) (1)
Isomerization of the binary complex of reduced acetylpyridine adenine dinucleotide and chicken H4 lactate dehydrogenase (1977) (1)
Increase in metabolic turnover of phosphatidic acid in brain slices caused by potassium (1961) (0)
Analysis of the mulv gp70s associated with lymphomagenesis induced in athymic mice by chronic antigenic stimulation. Abstr. (1983) (0)
Discussion: Part V (1984) (0)
PHOSPHOR YLA TIVE AND NONPHOSPHOR YLA TIVE PATHWAYS OF ELECTRON TRANSFER IN RAT LIVER MITOCHONDRIA * (0)
ANTICELLULAR ACTIVITY OF HUMAN INTERFERONS (1981) (0)
Guanosine Nucleotide Analogues as General Ligands in Affinity Chromatography (1978) (0)
Antibody studies with the multiple enzymes of horse liver alcohol dehydrogenase. II. (1968) (0)
Relationship of 3 alpha-hydroxysteroid dehydrogenase to pyridine nucleotide transhydrogenases. (1959) (0)
Stanford Moore issue: Dedication (1984) (0)
Discussion of Part III (1965) (0)
Chemical and Biological Aspects of Peptide Catecholamine Conjugates (1979) (0)
<a comparative study of the evolution of enzymes and nucleic acids< semi-annual status report, nov. 1, 1964 - apr. 30, 1965 (1965) (0)
Autobiography and Essays: Wanderings of a Biochemist . Fritz Lipmann. Wiley-Interscience, New York, 1971. x, 230 pp., illus. $8.95 (1971) (0)
Phosphorus metabolism in human diabetic acidosis. (1945) (0)
A comparative study of the evolution of enzymes and nucleic acids Semiannual progress report, 1 May - 30 Nov. 1967 (1967) (0)
An appreciation of Samuel P. Bessman (1985) (0)
Carbohydrate metabolism. (1951) (0)
[A mechanism for pyridine-nucleotide-dependent dependent dehydrogenases]. (1958) (0)
HEXITOL METABOLISM IN E . COLI mannitol points to the desirability of growing (0)
SYMPOSIUM ON ELECTRON TRANSPORT IN THE METABOLISM OF MICROORGANISMS (1955) (0)
Tissue distribution of doxorubicin (dx) and 4'deoxydoxorubicin (4'-deoxydx) in nude and conventional mice bearing colon tumors. Abstr. (1981) (0)
BIOLOGICAL FUNCTIONS OF LACTATE DEHYDROGENASE (1982) (0)
Biologically Active Catecholamines Covalently Bound to Glass Beads ( cyclic AMP / tissue culture / immobilized catecholamines / canine hearts ) (0)
Proliferation of t lymphocytes in athymic mice infected with pinworms. Abstr. (1980) (0)
Corrections - Studies on the Conformation of the Multiple Forms of Chicken Heart Aspartate Aminotransferase (1970) (0)
Separate physiological roles for two isozymes of pyridine nucleotide-linked glycerol-3-phosphate dehydrogenase in chickens. (1971) (0)
ENDOGENOUS MULV GP70 STIMULATION OF LYMPHOCYTES IN THE ATHYMIC MOUSE (1981) (0)
Passive transfer of lymphocytes from diabetic man to athymic mouse. (1979) (0)
8 – THE USE OF IMMOBILIZED DRUGS (1977) (0)
THE CHEMISTRY AND PHARMACOLOGY OF CATECHOLAMINES AND OTHER LOW MOLECULAR WEIGHT LIGANDS CONJUGATED TO CARRIERS (1979) (0)
Corrections - Developmental Changes of Mammalian Lactic Dehydrogenases (1964) (0)
Transforming growth factor production by a human hepatoma xenograft in athymic mice. Abstr. (1983) (0)

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