Neal S. Young
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Philosophy
Neal S. Young's Degrees
- Masters Medicine University of Pennsylvania
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(Suggest an Edit or Addition)Neal S. Young's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Regression of metastatic renal-cell carcinoma after nonmyeloablative allogeneic peripheral-blood stem-cell transplantation. (2000) (1016)
- The complement inhibitor eculizumab in paroxysmal nocturnal hemoglobinuria. (2006) (868)
- Erythrocyte P antigen: cellular receptor for B19 parvovirus. (1993) (798)
- Diagnosis and management of paroxysmal nocturnal hemoglobinuria. (2005) (705)
- Mutations in TERT, the gene for telomerase reverse transcriptase, in aplastic anemia. (2005) (693)
- Engraftment kinetics after nonmyeloablative allogeneic peripheral blood stem cell transplantation: full donor T-cell chimerism precedes alloimmune responses. (1999) (558)
- Multicenter phase 3 study of the complement inhibitor eculizumab for the treatment of patients with paroxysmal nocturnal hemoglobinuria. (2008) (550)
- Current concepts in the pathophysiology and treatment of aplastic anemia. (2006) (523)
- The pathophysiology of acquired aplastic anemia. (1997) (523)
- Fas antigen expression on CD34+ human marrow cells is induced by interferon gamma and tumor necrosis factor alpha and potentiates cytokine-mediated hematopoietic suppression in vitro. (1995) (513)
- Effect of the complement inhibitor eculizumab on thromboembolism in patients with paroxysmal nocturnal hemoglobinuria. (2007) (506)
- Chronic bone marrow failure due to persistent B19 parvovirus infection. (1987) (448)
- Why Current Publication Practices May Distort Science (2008) (442)
- Human thrombopoietin levels are high when thrombocytopenia is due to megakaryocyte deficiency and low when due to increased platelet destruction. (1996) (440)
- Current concepts in the pathophysiology and treatment of aplastic anemia. (2013) (415)
- Pure red-cell aplasia of 10 years' duration due to persistent parvovirus B19 infection and its cure with immunoglobulin therapy. (1989) (412)
- Horse versus rabbit antithymocyte globulin in acquired aplastic anemia. (2011) (387)
- Antithymocyte globulin and cyclosporine for severe aplastic anemia: association between hematologic response and long-term outcome. (2003) (354)
- Ibrutinib for previously untreated and relapsed or refractory chronic lymphocytic leukaemia with TP53 aberrations: a phase 2, single-arm trial. (2015) (354)
- Interferon is a mediator of hematopoietic suppression in aplastic anemia in vitro and possibly in vivo. (1985) (346)
- Circulating activated suppressor T lymphocytes in aplastic anemia. (1985) (341)
- Global Analyses of Human Immune Variation Reveal Baseline Predictors of Postvaccination Responses (2014) (337)
- Eltrombopag Added to Standard Immunosuppression for Aplastic Anemia (2017) (332)
- Resistance to parvovirus B19 infection due to lack of virus receptor (erythrocyte P antigen). (1994) (327)
- Replication of the B19 parvovirus in human bone marrow cell cultures. (1986) (319)
- Immune response to B19 parvovirus and an antibody defect in persistent viral infection. (1989) (318)
- Eltrombopag restores trilineage hematopoiesis in refractory severe aplastic anemia that can be sustained on discontinuation of drug. (2014) (315)
- Intensive immunosuppression with antithymocyte globulin and cyclosporine as treatment for severe acquired aplastic anemia. (1995) (306)
- Somatic Mutations in UBA1 and Severe Adult-Onset Autoinflammatory Disease. (2020) (303)
- Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells. (2009) (302)
- Mutations of the human telomerase RNA gene (TERC) in aplastic anemia and myelodysplastic syndrome. (2003) (298)
- A human parvovirus-like virus inhibits haematopoietic colony formation in vitro (1983) (290)
- Paroxysmal Nocturnal Hemoglobinuria Cells in Patients with Bone Marrow Failure Syndromes (1999) (288)
- Hepatic iron stores and plasma ferritin concentration in patients with sickle cell anemia and thalassemia major (1993) (280)
- How I treat acquired aplastic anemia. (2012) (278)
- Increased expression of Fas antigen on bone marrow CD34+ cells of patients with aplastic anaemia (1995) (270)
- PERSISTENT B19 PARVOVIRUS INFECTION AS A CAUSE OF SEVERE CHRONIC ANAEMIA IN CHILDREN WITH ACUTE LYMPHOCYTIC LEUKAEMIA (1988) (267)
- Antithymocyte globulin for patients with myelodysplastic syndrome (1997) (264)
- HLA-DR15 (DR2) is overrepresented in myelodysplastic syndrome and aplastic anemia and predicts a response to immunosuppression in myelodysplastic syndrome. (2002) (258)
- Late presentation of dyskeratosis congenita as apparently acquired aplastic anaemia due to mutations in telomerase RNA (2003) (255)
- Hematopoietic-specific microRNA expression in human cells. (2006) (254)
- Somatic Mutations and Clonal Hematopoiesis in Aplastic Anemia. (2015) (253)
- The problem of clonality in aplastic anemia: Dr Dameshek's riddle, restated. (1992) (252)
- Novel transcription map for the B19 (human) pathogenic parvovirus (1987) (248)
- Telomere diseases. (2009) (247)
- Factors affecting response and survival in patients with myelodysplasia treated with immunosuppressive therapy. (2008) (245)
- Acquired Aplastic Anemia (2002) (239)
- In-vivo dominant immune responses in aplastic anaemia: molecular tracking of putatively pathogenetic T-cell clones by TCR β-CDR3 sequencing (2004) (235)
- Distinct clinical outcomes for cytogenetic abnormalities evolving from aplastic anemia. (2002) (234)
- Rabbit ATG but not horse ATG promotes expansion of functional CD4+CD25highFOXP3+ regulatory T cells in vitro. (2007) (234)
- Interferon-gamma constitutively expressed in the stromal microenvironment of human marrow cultures mediates potent hematopoietic inhibition. (1996) (228)
- Self-assembled B19 parvovirus capsids, produced in a baculovirus system, are antigenically and immunogenically similar to native virions. (1991) (227)
- Pharmacologic doses of granulocyte colony-stimulating factor affect cytokine production by lymphocytes in vitro and in vivo. (2000) (226)
- Antithymocyte Globulin for Treatment of the Bone Marrow Failure Associated with Myelodysplastic Syndromes (2002) (226)
- Nitric oxide suppression of human hematopoiesis in vitro. Contribution to inhibitory action of interferon-gamma and tumor necrosis factor-alpha. (1995) (225)
- Bone marrow failure and the telomeropathies. (2014) (223)
- The gene encoding the nonstructural protein of B19 (human) parvovirus may be lethal in transfected cells (1988) (216)
- Telomere maintenance and human bone marrow failure. (2008) (215)
- Telomere length in leukocyte subpopulations of patients with aplastic anemia. (2001) (215)
- A Spectrum of Severe Familial Liver Disorders Associate with Telomerase Mutations (2009) (211)
- Infection of hematopoietic progenitor cells by human cytomegalovirus. (1992) (210)
- Eltrombopag and improved hematopoiesis in refractory aplastic anemia. (2012) (208)
- Hepatitis-associated aplastic anemia. (1997) (205)
- Studies of interferon as a regulator of hematopoietic cell proliferation. (1985) (204)
- Interferon is the suppressor of hematopoiesis generated by stimulated lymphocytes in vitro. (1984) (197)
- Regulated high level expression of a human gamma-globin gene introduced into erythroid cells by an adeno-associated virus vector. (1992) (195)
- An invertebrate coagulation system activated by endotoxin: evidence for enzymatic mediation. (1972) (195)
- Human parvovirus B19-induced epidemic acute red cell aplasia in patients with hereditary hemolytic anemia. (1986) (193)
- Hematologic and hematopoietic consequences of B19 parvovirus infection. (1988) (188)
- Predicting response to immunosuppressive therapy and survival in severe aplastic anaemia (2009) (186)
- Association of telomere length of peripheral blood leukocytes with hematopoietic relapse, malignant transformation, and survival in severe aplastic anemia. (2010) (182)
- Preferential suppression of trisomy 8 compared with normal hematopoietic cell growth by autologous lymphocytes in patients with trisomy 8 myelodysplastic syndrome. (2003) (181)
- Deficient CD4+ CD25+ FOXP3+ T regulatory cells in acquired aplastic anemia. (2007) (181)
- The treatment of severe acquired aplastic anemia. (1995) (179)
- Intracellular interferon-γ in circulating and marrow T cells detected by flow cytometry and the response to immunosuppressive therapy in patients with aplastic anemia (2002) (178)
- A prospective clinical and immunologic analysis of patients with serum sickness. (1984) (178)
- Constitutional hypomorphic telomerase mutations in patients with acute myeloid leukemia (2009) (176)
- The epidemiology of aplastic anemia in Thailand. (1999) (175)
- Human immunodeficiency virus type 1 protease inhibitor modulates activation of peripheral blood CD4(+) T cells and decreases their susceptibility to apoptosis in vitro and in vivo. (1999) (164)
- Hematologic effects of immunotherapy with lymphokine-activated killer cells and recombinant interleukin-2 in cancer patients. (1987) (164)
- Nucleotide sequencing and generation of an infectious clone of adeno-associated virus 3. (1996) (163)
- Distinctive gene expression profiles of CD34 cells from patients with myelodysplastic syndrome characterized by specific chromosomal abnormalities. (2004) (162)
- A severe and consistent deficit in marrow and circulating primitive hematopoietic cells (long-term culture-initiating cells) in acquired aplastic anemia. (1996) (161)
- Hematopoietic cell destruction by immune mechanisms in acquired aplastic anemia. (2000) (160)
- Involvement of Fas-mediated apoptosis in the inhibitory effects of interferon-alpha in chronic myelogenous leukemia. (1997) (160)
- Danazol Treatment for Telomere Diseases. (2016) (159)
- Drugs in the aetiology of agranulocytosis and aplastic anaemia (1996) (158)
- The epidemiology of acquired aplastic anemia (2008) (158)
- Role of Fas ligand and receptor in the mechanism of T-cell depletion in acquired immunodeficiency syndrome: effect on CD4+ lymphocyte depletion and human immunodeficiency virus replication. (1997) (158)
- Generation of Neutralizing Human Monoclonal Antibodies against Parvovirus B19 Proteins (1999) (156)
- Increased frequency of HLA-DR2 in patients with paroxysmal nocturnal hemoglobinuria and the PNH/aplastic anemia syndrome. (2001) (152)
- Retreatment with rabbit anti‐thymocyte globulin and ciclosporin for patients with relapsed or refractory severe aplastic anaemia (2006) (152)
- Constitutional telomerase mutations are genetic risk factors for cirrhosis (2011) (151)
- Congenital anaemia after transplacental B19 parvovirus infection (1994) (150)
- Aplastic Anemia: Acquired and Inherited (1994) (148)
- Th17 immune responses contribute to the pathophysiology of aplastic anemia. (2010) (148)
- Engraftment of hematopoietic progenitor cells transduced with the Fanconi anemia group C gene (FANCC). (1999) (144)
- Phenotypic correction of Fanconi anemia in human hematopoietic cells with a recombinant adeno-associated virus vector. (1994) (144)
- Treatment of severe aplastic anaemia with combined immunosuppression: anti‐thymocyte globulin, ciclosporin and mycophenolate mofetil (2006) (140)
- Treatment of severe aplastic anemia with a combination of horse antithymocyte globulin and cyclosporine, with or without sirolimus: a prospective randomized study (2009) (140)
- Neutralizing linear epitopes of B19 parvovirus cluster in the VP1 unique and VP1-VP2 junction regions (1993) (138)
- Relationship between bone marrow failure syndromes and the presence of glycophosphatidyl inositol‐anchored protein‐deficient clones (2001) (137)
- T-bet, a Th1 transcription factor, is up-regulated in T cells from patients with aplastic anemia. (2006) (136)
- Elevated circulating endothelial membrane microparticles in paroxysmal nocturnal haemoglobinuria (2004) (135)
- High-dose cyclophosphamide in severe aplastic anaemia: a randomised trial (2000) (135)
- Characterization of a virus that causes transient aplastic crisis. (1984) (133)
- Patterns of Infection in Patients with Aplastic Anemia and the Emergence of Aspergillus As a Major Cause of Death (1992) (133)
- Alemtuzumab treatment of intermediate-1 myelodysplasia patients is associated with sustained improvement in blood counts and cytogenetic remissions. (2009) (132)
- Recombinant adeno-associated virus-mediated gene transfer into hematopoietic progenitor cells. (1994) (126)
- Gamma-Interferon Gene Expression in the Bone Marrow of Patients with Aplastic Anemia (1994) (126)
- Danazol Treatment for Telomere Diseases. (2016) (125)
- A block in full-length transcript maturation in cells nonpermissive for B19 parvovirus (1992) (125)
- Oligoclonal and polyclonal CD4 and CD8 lymphocytes in aplastic anemia and paroxysmal nocturnal hemoglobinuria measured by V beta CDR3 spectratyping and flow cytometry. (2002) (123)
- Molecular, cellular and clinical aspects of parvovirus B19 infection. (1994) (121)
- Distinct EBV and CMV reactivation patterns following antibody-based immunosuppressive regimens in patients with severe aplastic anemia. (2006) (121)
- Effects of Systemically Administered Hydrocortisone on the Human Immunome (2016) (121)
- The structure of human parvovirus B19 at 8 A resolution. (1994) (121)
- GATA2 deficiency-associated bone marrow disorder differs from idiopathic aplastic anemia. (2015) (119)
- Interferon-gamma-induced gene expression in CD34 cells: identification of pathologic cytokine-specific signature profiles. (2006) (119)
- Parvovirus B19: implications for transfusion medicine. Summary of a workshop (2001) (118)
- Granulocyte colony-stimulating factor preferentially stimulates proliferation of monosomy 7 cells bearing the isoform IV receptor (2006) (115)
- Cytokine signature profiles in acquired aplastic anemia and myelodysplastic syndromes (2011) (114)
- Long-term outcome of pediatric patients with severe aplastic anemia treated with antithymocyte globulin and cyclosporine. (2008) (112)
- First continuous propagation of B19 parvovirus in a cell line. (1992) (111)
- Hematopoiesis in 3 dimensions: human and murine bone marrow architecture visualized by confocal microscopy. (2010) (111)
- New Insights into the Pathophysiology of Acquired Cytopenias. (2000) (110)
- Cryo-electron microscopy studies of empty capsids of human parvovirus B19 complexed with its cellular receptor. (1996) (108)
- Increased cytotoxic T cells with effector phenotype in aplastic anemia and myelodysplasia. (2001) (108)
- Functional characterization of natural telomerase mutations found in patients with hematologic disorders. (2007) (108)
- Impaired hematopoiesis in paroxysmal nocturnal hemoglobinuria/aplastic anemia is not associated with a selective proliferative defect in the glycosylphosphatidylinositol-anchored protein-deficient clone. (1997) (108)
- Enrichment of hematopoietic stem cells with SLAM and LSK markers for the detection of hematopoietic stem cell function in normal and Trp53 null mice. (2008) (107)
- Phenotypic and functional analysis of bone marrow progenitor cell compartment in bone marrow failure (1994) (107)
- Safety and immunogenicity of a recombinant parvovirus B19 vaccine formulated with MF59C.1. (2003) (106)
- Deep phenotyping of Tregs identifies an immune signature for idiopathic aplastic anemia and predicts response to treatment. (2016) (106)
- Unique region of the minor capsid protein of human parvovirus B19 is exposed on the virion surface. (1992) (106)
- Parvovirus B19 infection and hematopoiesis. (1995) (105)
- Adeno-associated virus type 2 binds to a 150-kilodalton cell membrane glycoprotein. (1996) (104)
- Limited heterogeneity of T cell receptor BV usage in aplastic anemia. (2001) (104)
- Bone marrow and peripheral blood lymphocyte phenotype in patients with bone marrow failure. (1994) (103)
- Coincident myelodysplastic syndrome and T‐cell large granular lymphocytic disease: clinical and pathophysiological features (2001) (103)
- Aplastic anemia and viral hepatitis. Non-A, Non-B, Non-C? (1992) (102)
- A knock-out model of paroxysmal nocturnal hemoglobinuria: Pig-a(-) hematopoiesis is reconstituted following intercellular transfer of GPI-anchored proteins. (1996) (102)
- Intracellular interferon-gamma in circulating and marrow T cells detected by flow cytometry and the response to immunosuppressive therapy in patients with aplastic anemia. (2002) (101)
- Aplastic anemia: pathophysiology and treatment. (2010) (101)
- A mouse model of lymphocyte infusion-induced bone marrow failure. (2004) (101)
- Short telomeres result in chromosomal instability in hematopoietic cells and precede malignant evolution in human aplastic anemia (2012) (99)
- Activity of alemtuzumab monotherapy in treatment-naive, relapsed, and refractory severe acquired aplastic anemia. (2012) (99)
- Overcoming graft rejection in heavily transfused and allo‐immunised patients with bone marrow failure syndromes using fludarabine‐based haematopoietic cell transplantation (2006) (99)
- Recombinant adeno-associated virus (rAAV)-mediated expression of a human gamma-globin gene in human progenitor-derived erythroid cells. (1994) (97)
- High-dose cyclophosphamide with autologous lymphocyte-depleted peripheral blood stem cell (PBSC) support for treatment of refractory chronic autoimmune thrombocytopenia. (2003) (96)
- Paroxysmal nocturnal hemoglobinuria clones in severe aplastic anemia patients treated with horse anti-thymocyte globulin plus cyclosporine (2010) (95)
- Human Parvoviruses (2016) (95)
- Genetic defects underlying paroxysmal nocturnal hemoglobinuria that arises out of aplastic anemia. (1995) (95)
- Ex Vivo-Generated CD36+ Erythroid Progenitors Are Highly Permissive to Human Parvovirus B19 Replication (2007) (95)
- Fas-mediated apoptosis is important in regulating cell replication and death in trisomy 8 hematopoietic cells but not in cells with other cytogenetic abnormalities. (2002) (95)
- Ultra-low dose interleukin-2 promotes immune-modulating function of regulatory T cells and natural killer cells in healthy volunteers. (2014) (95)
- CD34 cells from patients with trisomy 8 myelodysplastic syndrome (MDS) express early apoptotic markers but avoid programmed cell death by up-regulation of antiapoptotic proteins. (2006) (95)
- Functional characterization of telomerase RNA variants found in patients with hematologic disorders. (2005) (94)
- Infections in patients with aplastic anemia. (2009) (94)
- Lymphokine abnormalities in aplastic anemia: implications for the mechanism of action of antithymocyte globulin (1985) (94)
- Analysis of T-cell repertoire in hepatitis-associated aplastic anemia. (2004) (94)
- Human Serum Sickness: A Prospective Analysis of 35 Patients Treated with Equine Anti‐Thymocyte Globulin for Bone Marrow Failure (1988) (93)
- A putative nucleoside triphosphate-binding domain in the nonstructural protein of B19 parvovirus is required for cytotoxicity (1994) (92)
- Decreased infection-related mortality and improved survival in severe aplastic anemia in the past two decades. (2011) (92)
- Genetic and environmental effects in paroxysmal nocturnal hemoglobinuria: this little PIG-A goes "Why? Why? Why?". (2000) (92)
- Epstein-Barr virus in the bone marrow of patients with aplastic anemia. (1988) (91)
- A genetically engineered cell line that produces empty capsids of B19 (human) parvovirus. (1989) (91)
- A multicenter trial of antithymocyte globulin in aplastic anemia and related diseases (1988) (90)
- Gene expression profiling in CD34 cells to identify differences between aplastic anemia patients and healthy volunteers. (2004) (89)
- Intracellular expression of antibody fragments directed against HIV reverse transcriptase prevents HIV infection in vitro (1995) (89)
- Telomere Length Dynamics in Normal Individuals and in Patients with Hematopoietic Stem Cell‐Associated Disorders (2001) (89)
- Prevalence of parvovirus B19 in liver tissue: no association with fulminant hepatitis or hepatitis-associated aplastic anemia. (2003) (88)
- Inhibition of interferon regulatory factor-1 expression results in predominance of cell growth stimulatory effects of interferon-gamma due to phosphorylation of Stat1 and Stat3. (1997) (88)
- Dengue virus, a flavivirus, propagates in human bone marrow progenitors and hematopoietic cell lines. (1989) (87)
- Granulocyte transfusions in severe aplastic anemia: an eleven-year experience (2009) (86)
- HIV-1 suppression of hematopoiesis in vitro mediated by envelope glycoprotein and TNF-alpha. (1994) (86)
- Cyclosporine therapy of aplastic anaemia, congenital and acquired red cell aplasia (1989) (86)
- Bystander destruction of hematopoietic progenitor and stem cells in a mouse model of infusion-induced bone marrow failure. (2004) (86)
- Analysis of lymphocyte subsets in patients with aplastic anaemia (1984) (83)
- Parvoviruses and Bone Marrow Failure (1996) (82)
- Identification of a novel simian parvovirus in cynomolgus monkeys with severe anemia. A paradigm of human B19 parvovirus infection. (1994) (81)
- Parvovirus B19 as a cause of acquired chronic pure red cell aplasia (1994) (80)
- APLASTIC ANAEMIA IN THE ORIENT (1986) (79)
- Pathophysiologic mechanisms in acquired aplastic anemia. (2006) (79)
- Persistent parvovirus B19 infections in humans. (1989) (79)
- Nonisotopic detection of microRNA using digoxigenin labeled RNA probes. (2006) (79)
- T-cell immune responses to Wilms tumor 1 protein in myelodysplasia responsive to immunosuppressive therapy. (2011) (78)
- Effect of anticoagulants on multiplexed measurement of cytokine/chemokines in healthy subjects. (2012) (78)
- Mitochondrial DNA mutations in patients with myelodysplastic syndromes. (2003) (78)
- Telomere length is inherited with resetting of the telomere set-point (2010) (77)
- Aplastic anemia (2008) (75)
- Myelodysplastic syndromes. (2013) (75)
- A pilot study of the recombinant soluble human tumour necrosis factor receptor (p75)‐Fc fusion protein in patients with myelodysplastic syndrome (2002) (74)
- Minor Antigen H60-Mediated Aplastic Anemia Is Ameliorated by Immunosuppression and the Infusion of Regulatory T Cells (2007) (72)
- Expression and modulation of cellular receptors for interferon‐γ, tumour necrosis factor, and Fas on human bone marrow CD34+ cells (1997) (72)
- Human parvovirus B19 causes cell cycle arrest of human erythroid progenitors via deregulation of the E2F family of transcription factors. (2010) (70)
- Molecular Analysis of TCR Clonotypes in LGL: A Clonal Model for Polyclonal Responses1 (2004) (70)
- Neither human immunodeficiency virus-1 (HIV-1) nor HIV-2 infects most-primitive human hematopoietic stem cells as assessed in long-term bone marrow cultures. (1998) (69)
- Peptides derived from the unique region of B19 parvovirus minor capsid protein elicit neutralizing antibodies in rabbits. (1995) (68)
- Prevalence of the newly described human circovirus, TTV, in United States blood donors (2000) (68)
- Clonality in context: hematopoietic clones in their marrow environment. (2017) (68)
- Viruses and bone marrow failure. (1984) (68)
- Goose parvovirus--an autonomous member of the dependovirus genus? (1995) (68)
- Telomere attrition and candidate gene mutations preceding monosomy 7 in aplastic anemia. (2015) (67)
- Eltrombopag maintains human hematopoietic stem and progenitor cells under inflammatory conditions mediated by IFN-γ. (2019) (67)
- Infection of mononucleated phagocytes with human cytomegalovirus. (1993) (67)
- IFN-γ-mediated hematopoietic cell destruction in murine models of immune-mediated bone marrow failure. (2015) (67)
- Incidence of aplastic anemia in Bangkok. The Aplastic Anemia Study Group. (1991) (67)
- Defective telomere elongation and hematopoiesis from telomerase-mutant aplastic anemia iPSCs. (2013) (66)
- Lymphokine abnormalities in aplastic anemia: implications for the mechanism of action of antithymocyte globulin. (1985) (66)
- Large granular lymphocyte (LGL)-like clonal expansions in paroxysmal nocturnal hemoglobinuria (PNH) patients (2005) (66)
- Transcript profile of CD4+ and CD8+ T cells from the bone marrow of acquired aplastic anemia patients. (2004) (66)
- Somatic Mutations in "Benign" Disease. (2021) (66)
- Mutations in the SBDS gene in acquired aplastic anemia. (2007) (65)
- Transplant dose of CD34+ and CD3+ cells predicts outcome in patients with haematological malignancies undergoing T cell‐depleted peripheral blood stem cell transplants with delayed donor lymphocyte add‐back (2001) (65)
- Reactivation of hepatitis B with reappearance of hepatitis B surface antigen after chemotherapy and immunosuppression. (2009) (64)
- Changes in T-cell receptor VB repertoire in aplastic anemia: effects of different immunosuppressive regimens. (2002) (64)
- Investigation of SEN virus infection in patients with cryptogenic acute liver failure, hepatitis-associated aplastic anemia, or acute and chronic non-A-E hepatitis. (2003) (64)
- Safety and immunogenicity of a candidate parvovirus B19 vaccine. (2011) (64)
- Parvovirus B19 in human disease. (1997) (63)
- B19 parvovirus replicates in circulating cells of acutely infected patients. (1988) (63)
- Treatment optimization and genomic outcomes in refractory severe aplastic anemia treated with eltrombopag. (2019) (62)
- Memory Stem T Cells in Autoimmune Disease: High Frequency of Circulating CD8+ Memory Stem Cells in Acquired Aplastic Anemia (2016) (62)
- Agranulocytosis in Bangkok, Thailand: a predominantly drug-induced disease with an unusually low incidence. Aplastic Anemia Study Group. (1999) (61)
- Biological and immunological characterization of ATG and ALG (1986) (61)
- Dyskeratosis congenita: The first NIH clinical research workshop (2009) (61)
- A second neutralizing epitope of B19 parvovirus implicates the spike region in the immune response (1991) (61)
- HLA‐DR4 predicts haematological response to cyclosporine in T‐large granular lymphocyte lymphoproliferative disorders (2003) (60)
- Late complications following treatment for severe aplastic anemia (SAA) with high-dose cyclophosphamide (Cy): follow-up of a randomized trial. (2002) (59)
- Somatic Mutations in UBA1 Define a Distinct Subset of Relapsing Polychondritis Patients With VEXAS (2021) (59)
- Correction of the PNH defect by GPI-anchored protein transfer. (1998) (58)
- Telomere biology and telomere diseases: implications for practice and research. (2010) (58)
- Low drug attributability of aplastic anemia in Thailand. The Aplastic Anemia Study Group. (1997) (58)
- The relationship of aplastic anemia and PNH (2002) (58)
- Parvovirus infection and its treatment (1996) (57)
- In vitro and in vivo evidence of PNH cell sensitivity to immune attack after nonmyeloablative allogeneic hematopoietic cell transplantation. (2004) (56)
- Hematopoietic inhibition by interferon-gamma is partially mediated through interferon regulatory factor-1. (1995) (56)
- Eculizumab, a terminal complement inhibitor, improves anaemia in patients with paroxysmal nocturnal haemoglobinuria (2008) (56)
- Mitochondrial DNA sequence variation in single cells from leukemia patients. (2006) (55)
- Induction of nitric oxide synthase is involved in the mechanism of Fas‐mediated apoptosis in haemopoietic cells (1997) (55)
- Benign and malignant hematologic manifestations in patients with VEXAS syndrome due to somatic mutations in UBA1. (2021) (54)
- A functionally active retrovirus vector for gene therapy in Fanconi anemia group C (1994) (54)
- Most of the VP1 unique region of B19 parvovirus is on the capsid surface. (1995) (53)
- Decay-accelerating factor is present on paroxysmal nocturnal hemoglobinuria erythroid progenitors and lost during erythropoiesis in vitro (1985) (53)
- Aplastic anemia in rural Thailand: its association with grain farming and agricultural pesticide exposure. Aplastic Anemia Study Group. (1997) (53)
- Treatment of Diamond‐Blackfan anaemia with haematopoietic growth factors, granulocyte‐macrophage colony stimulating factor and interleukin 3: sustained remissions following IL‐3 (1991) (52)
- Rosuvastatin Alters the Proteome of High Density Lipoproteins: Generation of alpha-1-antitrypsin Enriched Particles with Anti-inflammatory Properties* (2015) (51)
- Neutrophil count in African Americans: lowering the target cutoff to initiate or resume chemotherapy? (2010) (51)
- AS03-adjuvanted H5N1 vaccine promotes antibody diversity and affinity maturation, NAI titers, cross-clade H5N1 neutralization, but not H1N1 cross-subtype neutralization (2018) (51)
- Hybrid DNA virus in Chinese patients with seronegative hepatitis discovered by deep sequencing (2013) (50)
- Recombinant humanized anti-IL-2 receptor antibody (daclizumab) produces responses in patients with moderate aplastic anemia. (2003) (50)
- Perforin gene mutations in patients with acquired aplastic anemia. (2006) (50)
- Bone Marrow Failure Syndromes (2000) (49)
- Superior growth of glycophosphatidy linositol-anchored protein-deficient progenitor cells in vitro is due to the higher apoptotic rate of progenitors with normal phenotype in vivo. (2002) (49)
- Increased soluble urokinase plasminogen activator receptor (suPAR) is associated with thrombosis and inhibition of plasmin generation in paroxysmal nocturnal hemoglobinuria (PNH) patients. (2008) (49)
- Single-cell RNA-seq reveals a distinct transcriptome signature of aneuploid hematopoietic cells. (2017) (48)
- Experimental infection of cynomolgus monkeys with simian parvovirus (1997) (48)
- VP1u phospholipase activity is critical for infectivity of full-length parvovirus B19 genomic clones. (2008) (48)
- Deep sequencing and flow cytometric characterization of expanded effector memory CD8+CD57+ T cells frequently reveals T-cell receptor Vβ oligoclonality and CDR3 homology in acquired aplastic anemia (2018) (47)
- Directed therapy for patients with myelodysplastic syndromes (MDS) by suppression of cyclin D1 with ON 01910.Na. (2012) (47)
- Genetic variation in telomeric repeat binding factors 1 and 2 in aplastic anemia. (2006) (47)
- Gene marking and gene therapy directed at primary hematopoietic cells (1996) (46)
- Indiscriminate activity from the B19 parvovirus p6 promoter in nonpermissive cells. (1991) (46)
- Translational regulation of B19 parvovirus capsid protein production by multiple upstream AUG triplets. (1988) (45)
- Relative incidence of agranulocytosis and aplastic anemia (2006) (45)
- A trial of recombinant human interleukin‐1 in patients with severe refractory aplastic anaemia (1992) (45)
- A functionally active retrovirus vector for gene therapy in Fanconi anemia group C. (1994) (45)
- The graft-versus-leukemia effect of nonmyeloablative stem cell allografts may not be sufficient to cure chronic myelogenous leukemia (2003) (45)
- Marked mitochondrial DNA sequence heterogeneity in single CD34+ cell clones from normal adult bone marrow. (2004) (44)
- Differential gene expression in hematopoietic progenitors from paroxysmal nocturnal hemoglobinuria patients reveals an apoptosis/immune response in ‘normal’ phenotype cells (2005) (44)
- Transfer of glycosylphosphatidylinositol-anchored proteins to deficient cells after erythrocyte transfusion in paroxysmal nocturnal hemoglobinuria. (2004) (44)
- Natural history of pulmonary fibrosis in two subjects with the same telomerase mutation. (2011) (44)
- Aplastic anaemia (1995) (44)
- Decreased interleukin 1 production in aplastic anaemia (1989) (43)
- Decreased susceptibility of leukemic cells with PIG-A mutation to natural killer cells in vitro. (2002) (43)
- Retroviral mediated gene transfer of the Fanconi anemia complementation group C gene to hematopoietic progenitors of group C patients. (1997) (43)
- Clinical utility of gene panel-based testing for hereditary myelodysplastic syndrome/acute leukemia predisposition syndromes (2017) (43)
- Selective reduction of natural killer T cells in the bone marrow of aplastic anaemia (2002) (42)
- 4 Viruses and bone marrow failure (1989) (41)
- Characterization of the hematopoietic defect in paroxysmal nocturnal hemoglobinuria. (1986) (41)
- Moderate-dose cyclophosphamide for severe aplastic anemia has significant toxicity and does not prevent relapse and clonal evolution. (2014) (41)
- Prevalence of GBV‐C/HGV, a novel ‘hepatitis’ virus, in patients with aplastic anaemia (1997) (40)
- The transcriptional regulator YY1 binds to the 5'-terminal region of B19 parvovirus and regulates P6 promoter activity (1994) (40)
- A multicenter trial of antithymocyte globulin in aplastic anemia and related diseases. (1988) (40)
- Mitochondrial DNA sequence heterogeneity in circulating normal human CD34 cells and granulocytes. (2004) (40)
- Parvovirus particles as platforms for protein presentation. (1994) (40)
- Analysis of natural killer cells in patients with aplastic anemia. (1986) (40)
- Activated platelets of patients with paroxysmal nocturnal hemoglobinuria express cellular prion protein. (2002) (39)
- Sustained long‐term hematologic recovery despite a marked quantitative defect in the stem cell compartment of patients with aplastic anemia after immunosuppressive therapy (2000) (39)
- VEXAS syndrome (2021) (39)
- Donor-derived MDS/AML in families with germline GATA2 mutation. (2018) (39)
- Analysis of the expression of glycosylphosphatidylinositol anchored proteins on platelets from patients with paroxysmal nocturnal hemoglobinuria. (1996) (39)
- Decreased plasma cytokines are associated with low platelet counts in aplastic anemia and immune thrombocytopenic purpura (2012) (39)
- Cytokine gene polymorphisms in acquired bone marrow failure (2007) (38)
- Telomere length and telomerase complex mutations in pediatric acute myeloid leukemia (2012) (37)
- Multiple Layers of Chimerism in a Single-Stranded DNA Virus Discovered by Deep Sequencing (2015) (37)
- Biological and immunological characterization of ATG and ALG. (1986) (37)
- Cyclosporine is required to prevent severe acute GVHD following T-cell-depleted peripheral blood stem cell transplantation (2003) (36)
- Lymphocyte phenotype and lymphokines following anti‐thymocyte globulin therapy in patients with aplastic anaemia (1987) (36)
- Bone marrow skeletal stem/progenitor cell defects in dyskeratosis congenita and telomere biology disorders. (2015) (36)
- Aging and Hematopoiesis. (2019) (36)
- Macrophage TNF-α licenses donor T cells in murine bone marrow failure and can be implicated in human aplastic anemia. (2018) (36)
- Regional patterns in the incidence of aplastic anemia in Thailand (1999) (36)
- Autoimmunity and Its Treatment in Aplastic Anemia (1997) (35)
- Optimization of therapy for severe aplastic anemia based on clinical, biologic, and treatment response parameters: conclusions of an international working group on severe aplastic anemia convened by the Blood and Marrow Transplant Clinical Trials Network, March 2010. (2011) (35)
- In vivo effects of horse and rabbit antithymocyte globulin in patients with severe aplastic anemia (2014) (34)
- Acquired aplastic anemia. (1999) (34)
- An association of aplastic anaemia in Thailand with low socioeconomic status (1995) (34)
- Rapamycin is highly effective in murine models of immune-mediated bone marrow failure (2017) (34)
- Acquired somatic mutations in PNH reveal long-term maintenance of adaptive NK cells independent of HSPCs. (2017) (34)
- Reducing Health Inequities in the U.S.: Recommendations From the NHLBI's Health Inequities Think Tank Meeting. (2016) (34)
- Codon Optimization of Human Parvovirus B19 Capsid Genes Greatly Increases Their Expression in Nonpermissive Cells (2010) (34)
- Cloning and sequencing of the simian parvovirus genome. (1995) (34)
- Age-dependent accumulation of mtDNA mutations in murine hematopoietic stem cells is modulated by the nuclear genetic background. (2007) (33)
- Early and late gene expression in UT-7 cells infected with B19 parvovirus. (1993) (33)
- Flaviviruses and bone marrow failure. (1990) (33)
- Pulmonary arteriovenous malformations: an uncharacterised phenotype of dyskeratosis congenita and related telomere biology disorders (2017) (33)
- The role of the Th1 transcription factor T-bet in a mouse model of immune-mediated bone-marrow failure. (2010) (33)
- Expression of interferon-gamma by stromal cells inhibits murine long-term repopulating hematopoietic stem cell activity. (1999) (32)
- The role of interleukin-converting enzyme in Fas-mediated apoptosis in HIV-1 infection. (1998) (32)
- Oral manifestations in patients with aplastic anemia. (2001) (32)
- Prolonged cyclosporine administration after antithymocyte globulin delays but does not prevent relapse in severe aplastic anemia (2014) (31)
- Pathogenic TERT promoter variants in telomere diseases (2018) (31)
- Human telomere disease due to disruption of the CCAAT box of the TERC promoter. (2011) (31)
- Pathophysiology and management of thrombocytopenia in bone marrow failure: possible clinical applications of TPO receptor agonists in aplastic anemia and myelodysplastic syndromes (2013) (31)
- Parvovirus B19 empty capsids as antigen carriers for presentation of antigenic determinants of dengue 2 virus. (2006) (31)
- Antithymocyte globulin hypersensitivity in bone marrow failure patients. (1988) (30)
- Secondary colony formation after long‐term bone marrow culture using peripheral blood and bone marrow of HIV‐infected patients (1997) (30)
- The management of paroxysmal nocturnal hemoglobinuria: recent advances in diagnosis and treatment and new hope for patients. (2009) (30)
- Cutaneous manifestations of serum sickness in patients receiving antithymocyte globulin. (1985) (30)
- The Simian Parvoviruses (1997) (29)
- Bethesda Handbook of Clinical Hematology (2008) (29)
- Human Parvovirus B19: Pathogenesis of Disease (1997) (29)
- Bone marrow failure and the new telomere diseases: practice and research (2012) (29)
- Circulating exosomal microRNAs in acquired aplastic anemia and myelodysplastic syndromes (2018) (29)
- Alemtuzumab in T-cell large granular lymphocytic leukaemia: interim results from a single-arm, open-label, phase 2 study. (2016) (29)
- Long noncoding RNAs of single hematopoietic stem and progenitor cells in healthy and dysplastic human bone marrow (2018) (28)
- Lymphocytes with Aberrant Expression of Fas or Fas Ligand Attenuate Immune Bone Marrow Failure in a Mouse Model1 (2009) (28)
- Age-adjusted recipient pretransplantation telomere length and treatment-related mortality after hematopoietic stem cell transplantation. (2011) (28)
- Successful surgical management of neutropenic enterocolitis in two patients with severe aplastic anemia. Case reports and review of the literature. (1993) (28)
- Should irradiated blood products be given routinely to all patients with aplastic anaemia undergoing immunosuppressive therapy with antithymocyte globulin (ATG)? A survey from the European Group for Blood and Marrow Transplantation Severe Aplastic Anaemia Working Party (2010) (27)
- Mitochondrial DNA mutations in single human blood cells. (2015) (27)
- Lymphocytes and lymphokines in aplastic anemia: pathogenic role and implications for pathogenesis. (1987) (27)
- Somatic mutations in lymphocytes in patients with immune-mediated aplastic anemia (2021) (27)
- Multiple antigenic peptides as vaccine platform for the induction of humoral responses against dengue-2 virus. (2007) (26)
- Defective stromal cell function in a mouse model of infusion-induced bone marrow failure. (2005) (26)
- Eltrombopag mobilizes iron in patients with aplastic anemia. (2018) (25)
- Immune pathophysiology of acquired aplastic anaemia (1996) (25)
- Epigenetic landscape of the TERT promoter: a potential biomarker for high risk AML/MDS (2016) (25)
- The Spectrum of Hepatic Involvement in Patients With Telomere Disease (2019) (25)
- Serum sickness and haematopoietic recovery with antithymocyte globulin in bone marrow failure patients (1986) (25)
- Hemoglobin switching in sheep: Only the γ gene is in the active conformation in fetal liver but all the β and γ genes are in the active conformation in bone marrow (1978) (25)
- Eltrombopag monotherapy can improve hematopoiesis in patients with low to intermediate risk-1 myelodysplastic syndrome. (2020) (25)
- Clinical and epidemiological features of simian parvovirus infection in cynomolgus macaques with severe anemia. (1996) (25)
- Paroxysmal nocturnal hemoglobinuria and myelodysplastic sydromes: clonal expansion of PIG-A-mutant hematopoietic cells in bone marrow failure (2009) (25)
- External Contamination in Single Cell mtDNA Analysis (2007) (24)
- Use of household pesticides and the risk of aplastic anaemia in Thailand. The Aplastic Anemia Study Group. (1997) (24)
- Extensive latent retroviral infection in bone marrow of patients with HTLV-I-associated neurologic disease. (1997) (24)
- Eltrombopag for patients with moderate aplastic anemia or uni-lineage cytopenias. (2020) (23)
- Formation of empty B19 parvovirus capsids by the truncated minor capsid protein (1994) (23)
- Identification of novel microRNA signatures linked to acquired aplastic anemia (2015) (23)
- Long-term follow-up of patients with moderate aplastic anemia and pure red cell aplasia treated with daclizumab (2010) (23)
- Anti-K562 cell monoclonal antibodies recognize hematopoietic progenitors. (1981) (23)
- Shared and individual specificities of immunodominant cytotoxic T-cell clones in paroxysmal nocturnal hemoglobinuria as determined by molecular analysis. (2004) (23)
- Increased risk for aplastic anemia and myelodysplastic syndrome in individuals lacking glutathione S‐transferase genes (2004) (23)
- Cytogenetic abnormalities in paroxysmal nocturnal haemoglobinuria usually occur in haematopoietic cells that are glycosylphosphatidylinositol‐anchored protein (GPI‐AP) positive (2003) (23)
- Upstream sequences within the terminal hairpin positively regulate the P6 promoter of B19 parvovirus. (1991) (23)
- T-bet , a Th 1 transcription factor , is up-regulated in T cells from patients with aplastic anemia (2006) (23)
- Horse antithymocyte globulin as salvage therapy after rabbit antithymocyte globulin for severe aplastic anemia (2014) (22)
- Preliminary X-ray crystallographic investigation of human parvovirus B19. (1991) (22)
- Global Analyses of Human Immune Variation Reveal Baseline Predictors of Postvaccination Responses (2014) (22)
- Accumulation of mtDNA variations in human single CD34+ cells from maternally related individuals: effects of aging and family genetic background. (2013) (21)
- Circulating S100A8 and S100A9 protein levels in plasma of patients with acquired aplastic anemia and myelodysplastic syndromes (2019) (21)
- Expansion of haematopoietic stem cells from normal donors and bone marrow failure patients by recombinant hoxb4 (2009) (21)
- Eltrombopag Added to Standard Immunosuppression for Aplastic Anemia Accelerates Count Recovery and Increases Response Rates (2015) (21)
- A study of human serum sickness. (1985) (21)
- Paroxysmal nocturnal hemoglobinuria: current issues in pathophysiology and treatment. (2005) (21)
- Functional mapping of the genome of the B19 (human) parvovirus by in vitro translation after negative hybrid selection (1988) (21)
- High prevalence of hepatitis C viremia among aplastic anemia patients and controls from Thailand. (1992) (20)
- Heterozygous RTEL1 variants in bone marrow failure and myeloid neoplasms. (2018) (20)
- Long-term outcome of fludarabine-based reduced-intensity allogeneic hematopoietic cell transplantation for debilitating paroxysmal nocturnal hemoglobinuria. (2014) (20)
- Mitochondrial DNA spectra of single human CD34+ cells, T cells, B cells, and granulocytes. (2005) (20)
- Long-term outcomes in severe aplastic anemia patients treated with immunosuppression and eltrombopag: a phase 2 study. (2021) (20)
- Modest truncation of the major capsid protein abrogates B19 parvovirus capsid formation (1995) (20)
- Hemoglobin switching in sheep. (1980) (20)
- The Third Consensus Conference on the treatment of aplastic anemia (2011) (19)
- Expression of stem cell inhibitor (SCI) gene in patients with bone marrow failure. (1992) (19)
- Inhibition of interleukin-1beta-converting enzyme in human hematopoietic progenitor cells results in blockade of cytokine-mediated apoptosis and expansion of their proliferative potential. (1998) (19)
- Thrombotic Complications in PNH (2000) (19)
- Isolation of antibodies specific to sickle hemoglobin by affinity chromatography using a synthetic peptide. (1975) (19)
- A mutation in the H/ACA box of telomerase RNA component gene (TERC) in a young patient with myelodysplastic syndrome (2014) (18)
- Heterozygous RTEL1 variants in bone marrow failure and myeloid neoplasms. (2018) (18)
- Eltrombopag added to immunosuppression for children with treatment‐naïve severe aplastic anaemia (2021) (18)
- Telomerase Variant A279T Induces Telomere Dysfunction and Inhibits Non-Canonical Telomerase Activity in Esophageal Carcinomas (2014) (18)
- Genomic instability in bone marrow failure syndromes (2004) (18)
- Long-term adaptation to hypoxia preserves hematopoietic stem cell function. (2016) (18)
- Parvovirus B19 infection and bone marrow transplantation (2005) (18)
- Immunosuppressive Treatment of Acquired Aplastic Anemia and Immune-Mediated Bone Marrow Failure Syndromes (2002) (18)
- A trial of immunotherapy in aplastic anemia and pure red cell aplasia (1983) (17)
- Establishment of an erythroid cell line from primary CD36+ erythroid progenitor cells. (2010) (17)
- Recombinant viral-like particles of parvovirus B19 as antigen carriers of anthrax protective antigen. (2006) (17)
- Graft-versus-host disease: role of inflammation in the development of chromosomal abnormalities of keratinocytes. (2010) (17)
- A plasma microRNA signature as a biomarker for acquired aplastic anemia (2016) (17)
- Decreased TCR ζ‐chain expression in T cells from patients with acquired aplastic anaemia (2007) (17)
- 2 B19 parvovirus (1995) (17)
- Myelodysplasia and Bone Marrow Manifestations of Somatic UBA1 Mutated Autoinflammatory Disease (2020) (17)
- Feline parvovirus propagates in cat bone marrow cultures and inhibits hematopoietic colony formation in vitro (1989) (16)
- Centrosome amplification and aneuploidy in bone marrow failure patients (2004) (16)
- Effects of rosuvastatin on the immune system in healthy volunteers with normal serum cholesterol. (2019) (16)
- Association of seropositivity for hepatitis viruses and aplastic anemia in Thailand (1997) (16)
- Etiologic mechanisms of hematopoietic failure. (1990) (15)
- B19 parvovirus. (1995) (15)
- Subunit interaction in B19 parvovirus empty capsids (2005) (15)
- Telomere Length Recovery: A Strong Predictor of Overall Survival in Acute Promyelocytic Leukemia (2016) (15)
- Immune-mediated bone marrow failure in C57BL/6 mice. (2015) (15)
- Deficient CD 4 CD 25 FOXP 3 T regulatory cells in acquired aplastic anemia (2007) (15)
- Telomere length and associations with somatic mutations and clinical outcomes in acute myeloid leukemia. (2016) (15)
- A trial of recombinant human superoxide dismutase in patients with Fanconi anaemia (1993) (15)
- Monoclonal gammopathy‐associated pure red cell aplasia (2016) (14)
- Brief Communication: Successful Treatment of Pure Red-Cell Aplasia with an AntiInterleukin-2 Receptor Antibody (Daclizumab) (2006) (14)
- Antibodies to an NH2-terminal fragment of betaS globin. II. Specificity and isolation of antibodies for the sickle mutation. (1976) (14)
- Telomerase enzyme deficiency promotes metabolic dysfunction in murine hepatocytes upon dietary stress (2018) (14)
- The Immune System as Mediator of Virus‐Associated Bone Marrow Failure: B19 Parvovirus and Epstein‐Barr Virus (1989) (14)
- Interleukin-23 receptor (IL-23R) gene polymorphisms in acquired aplastic anemia (2009) (14)
- A Randomized Trial of Horse Versus Rabbit Antithymocyte Globulin In Severe Acquired Aplastic Anemia (2010) (14)
- LACK OF EVIDENCE FOR PARVOVIRUS B19 VIRAEMIA IN CHILDREN WITH CHRONIC NEUTROPENIA (1994) (14)
- Predicting response of severe aplastic anemia to immunosuppression combined with eltrombopag (2021) (14)
- Regulatory Mutations in GATA2 Associated with Aplastic Anemia (2012) (14)
- Different haematopoietic growth factors have different capacity in overcoming the in vitro interferon gamma‐induced suppression of bone marrow progenitor cells (1990) (13)
- Immunologic effects on the haematopoietic stem cell in marrow failure. (2021) (13)
- CD34+ cells from paroxysmal nocturnal hemoglobinuria (PNH) patients are deficient in surface expression of cellular prion protein (PrPc). (2003) (13)
- Saccharomyces cerevisiae-derived virus-like particle parvovirus B19 vaccine elicits binding and neutralizing antibodies in a mouse model for sickle cell disease. (2017) (13)
- Human parvovirus B19 can infect cynomolgus monkey marrow cells in tissue culture (1995) (13)
- Anemia of Central Origin. (2015) (12)
- Parvovirus B19 integration into human CD36+ erythroid progenitor cells. (2017) (12)
- Aptamer-based proteomics of serum and plasma in acquired aplastic anemia. (2018) (12)
- PPARγ antagonist attenuates mouse immune-mediated bone marrow failure by inhibition of T cell function (2016) (12)
- Research directions in paroxysmal nocturnal hemoglobinuria. (1999) (12)
- Role of perforin-mediated cell apoptosis in murine models of infusion-induced bone marrow failure. (2009) (11)
- Optimization and standardization of fluorescent cell barcoding for multiplexed flow cytometric phenotyping (2017) (11)
- Analysis of Deficiency of Adenosine Deaminase 2 Pathogenesis Based on Single Cell RNA Sequencing of Monocytes (2019) (11)
- Reply to Naccache et al: Viral sequences of NIH-CQV virus, a contamination of DNA extraction method (2014) (11)
- Outcomes in Pediatric Patients with Severe Aplastic Anemia Treated with Standard Immunosuppression and Eltrombopag (2019) (10)
- Persistent elevation of plasma thrombopoietin levels after treatment in severe aplastic anemia. (2017) (10)
- Deficit of circulating CD19+CD24hiCD38hi regulatory B cells in severe aplastic anaemia (2020) (10)
- Eltrombopag for Refractory Severe Aplastic Anemia: Dosing Regimens, Long-Term Follow-up, Clonal Evolution and Somatic Mutation Profiling (2017) (10)
- Effects of granulocyte–colony‐stimulating factor on Monosomy 7 aneuploidy in healthy hematopoietic stem cell and granulocyte donors (2012) (10)
- Erratum: A pilot study of the recombinant soluble human tumour necrosis factor receptor (p75)-Fc fusion protein in patients with myelodysplastic syndrome (British Journal of Haematology 117 (119-126)) (2002) (10)
- Mobilization, collection, and immunomagnetic selection of peripheral blood CD34 cells in recovered aplastic anemia patients (2007) (10)
- Perspectives from NHLBI Global Health Think Tank Meeting for Late Stage (T4) Translation Research. (2017) (10)
- Telomere content measurement in human hematopoietic cells: Comparative analysis of qPCR and Flow‐FISH techniques (2016) (10)
- Human parvovirus B19 infections in infants and children. (1997) (10)
- A new syndrome of familial aplastic anemia and chronic liver disease. (1997) (10)
- Sequencing of RNA in single cells reveals a distinct transcriptome signature of hematopoiesis in GATA2 deficiency. (2020) (9)
- Pancytopenia secondary to parvovirus B19 infection in a child with acute lymphoblastic leukemia, mimicking leukemic relapse (1995) (9)
- The Etiology of Acquired Aplastic Anemia (2000) (9)
- Acquired sideroblastic anaemia following progesterone therapy (1994) (9)
- CRISPR/Cas9-mediated ASXL1 mutations in U937 cells disrupt myeloid differentiation (2018) (9)
- Mouse medicine and human biology. (2013) (9)
- Phenotypic and functional characterization of a mouse model of targeted Pig-a deletion in hematopoietic cells (2010) (9)
- Determining which patients with myelodysplastic syndrome will respond to immunosuppressive treatment. (2006) (9)
- Patients with bone marrow failure demonstrate decreased cutaneous reactivity to human C5a. (1987) (9)
- Feline parvovirus propagates in cat bone marrow cultures and inhibits hematopoietic colony formation in vitro. (1989) (9)
- Mitochondrial DNA Sequence Heterogeneity of Single CD34+ Cells After Nonmyeloablative Allogeneic Stem Cell Transplantation (2007) (8)
- Neutropenia associated with large granular lymphocytes responsive to corticosteroids in vitro and in vivo (1987) (8)
- Prevalence of somatic mutations in patients with aplastic anemia using peripheral blood cfDNA as compared with BM (2017) (8)
- Frequent HPRT mutations in paroxysmal nocturnal haemoglobinuria reflect T cell clonal expansion, not genomic instability (2004) (8)
- Somatic mosaicism in inherited bone marrow failure syndromes. (2021) (8)
- Telomere Length of Peripheral Blood Leukocytes Predicts Relapse and Clonal Evolution after Immunosuppressive Therapy in Severe Aplastic Anemia (2008) (8)
- Comprehensive network modeling from single cell RNA sequencing of human and mouse reveals well conserved transcription regulation of hematopoiesis (2020) (8)
- MHC class II upregulation and colocalization with Fas in experimental models of immune-mediated bone marrow failure. (2011) (8)
- Safety and Efficacy of the Terminal Complement Inhibitor Eculizumab in Patients with Paroxysmal Nocturnal Hemoglobinuria: Interim Shepherd Phase III Clinical Study. (2006) (8)
- COVID‐19 infection in patients with severe aplastic anaemia (2021) (8)
- Persistent parvovirus B19 infection (1995) (8)
- The function of lymphocytes in normal and suppressed hematopoiesis (2004) (8)
- Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing. (2018) (8)
- Analysis of deficiency of adenosine deaminase 2 pathogenesis based on single‐cell RNA sequencing of monocytes (2021) (7)
- The Terminal Complement Inhibitor Eculizumab Reduces Thrombosis in Patients with Paroxysmal Nocturnal Hemoglobinuria. (2006) (7)
- Is there a direct effect of antithymocyte globulin on hematopoiesis? (2004) (7)
- Alemtuzumab in T-cell large granular lymphocytic leukaemia: a phase 2 study (2015) (7)
- Immune pathophysiology of aplastic anemia (2002) (7)
- The NH2-terminal region of the sickle hemoglobin beta chain. II. Characterization of monospecific antibodies. (1976) (7)
- High throughput pSTAT signaling profiling by fluorescent cell barcoding and computational analysis. (2019) (7)
- Blood consult: paroxysmal nocturnal hemoglobinuria and its complications. (2013) (7)
- Suppression of Cyclin D1 by on 01910.Na Is Associated with Decreased Survival of Trisomy 8 Myelodyplastic Bone Marrow Progenitors: A Potential Targetted Therapy. (2007) (7)
- Peromyscus leucopus mice: a potential animal model for haematological studies (2014) (7)
- T Cell Transcriptomes from Paroxysmal Nocturnal Hemoglobinuria Patients Reveal Novel Signaling Pathways (2016) (7)
- Apparent mtDNA sequence heterogeneity in single human blood CD34+ cells is markedly affected by storage and transport. (2013) (7)
- Introduction: acquired aplastic anemia. (2000) (7)
- Interferon-γ Perturbs Key Signaling Pathways Induced By Thrombopoietin, but Not Eltrombopag, in Human Hematopoietic Stem/Progenitor Cells (2016) (7)
- Gene expression profiling in CD 34 cells to identify differences between aplastic anemia patients and healthy volunteers (2003) (6)
- Human parvovirus B 19 causes cell cycle arrest of human erythroid progenitors via deregulation of the E 2 F family of transcription factors (2010) (6)
- Viruses and bone marrow : basic research and clinical practice (1993) (6)
- Constitutional Loss-of-Function Mutations in Telomerase Are Genetic Risk Factors for Acute Myeloid Leukemia. (2007) (6)
- G-CSF and monosomy 7 in marrow failure patients (2002) (6)
- Telomere Length Is Associated with Specific Mutations and Mutation Classes in Patients with Acute Myeloid Leukemia (2014) (6)
- Drugs and chemicals as agents of bone marrow failure (1988) (6)
- Interleukin-18 plays a dispensable role in murine and likely also human bone marrow failure. (2019) (6)
- Immunosuppressive Treatment Is Associated with Durable Responses and a Survival Advantage in Younger Patients with int-1 Myelodysplastic Syndrome. (2005) (6)
- Treatment with the Terminal Complement Inhibitor Eculizumab Improves Anemia in Patients with Paroxysmal Nocturnal Hemoglobinuria: Phase III Triumph Study Results. (2006) (6)
- Chronological Analysis of Clonal Evolution in Acquired Aplastic Anemia (2014) (6)
- Hematopoietic lineage skewing and intestinal epithelia degeneration in aged mice with telomerase RNA component deletion (2015) (6)
- Soluble Urokinase Plasminogen Activator Receptor Is Increased in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) and Thrombosis and Inhibits Plasmin Generation In Vitro and Promotes Thrombosis in the Mouse Model. (2006) (6)
- Detectable mutations precede late myeloid neoplasia in aplastic anemia (2020) (6)
- Even “Moderate” Dose Cyclophosphamide for Severe Aplastic Anemia Is Associated with Significant Toxicities and Does Not Prevent Relapse and Clonal Evolution (2012) (6)
- Rapid donor T‐cell engraftment increases the risk of chronic graft‐versus‐host disease following salvage allogeneic peripheral blood hematopoietic cell transplantation for bone marrow failure syndromes (2013) (5)
- Conventional Co-Housing Modulates Murine Gut Microbiota and Hematopoietic Gene Expression (2020) (5)
- No impact of lentiviral transduction on hematopoietic stem/progenitor cell telomere length or gene expression in the rhesus macaque model. (2014) (5)
- Monosomy 7 Detected by FISH at Disease Presentation Is a Marker for Non-Response to Immunosuppression. (2007) (5)
- Hematologic manifestations and diagnosis of parvovirus B19 infections. (2006) (5)
- Oligoclonal T-cell expansion in a patient with bone marrow failure after CD19 CAR-T therapy for Richter-transformed DLBCL (2022) (5)
- Distinguishing constitutional from acquired bone marrow failure in the hematology clinic. (2021) (5)
- Tumor Necrosis Factor-Alpha and Interleukin-6 Promoter Gene Polymorphisms in Acquired Bone Marrow Failure Syndromes. (2004) (5)
- Eltrombopag Can Stimulate Trilineage Hematopoiesis with Transfusion Independence in Patients with Refractory Severe Aplastic Anemia: Results From a Phase II Trial (2011) (5)
- Long-term outcomes in myelodysplastic syndrome patients treated with alemtuzumab. (2019) (5)
- Functional Characterization of Telomerase RNA Variants Found in Patients with Hematological Disorders. (2004) (5)
- Attenuation of immune‐mediated bone marrow damage in conventionally housed mice (2020) (5)
- Corrigendum: Effects of Systemically Administered Hydrocortisone on the Human Immunome (2016) (5)
- Sex Hormones Up-Regulate Telomerase Activity of Normal Human Hematopoietic Cells and Restore Telomerase Activity in Carriers of Telomerase Complex Mutations. (2005) (5)
- Damage control and its costs: BM failure in Fanconi anemia stems from overactive p53/p21. (2012) (5)
- Treatment of Severe Aplastic Anemia with Combined Immunosuppression: Antithymocyte Globulin (ATG), Cyclosporine A (CSA), and Mycophenolate Mofetil (MMF). (2005) (5)
- Regulation of human globin gene expression in mouse erythroleukemia × human fibroblast hybrid cells (1982) (5)
- Telomere length in paroxysmal nocturnal hemoglobinuria correlates with clone size. (2007) (5)
- Alemtuzumab (Campath) Monotherapy for Severe Aplastic Anemia. (2010) (5)
- Paroxysmal nocturnal hemoglobinuria with copy number‐neutral 6pLOH in GPI (+) but not in GPI (−) granulocytes (2014) (5)
- Myelodysplasia with Trisomy 8 Is Associated with a Cytotoxic CD8 T Cell Immune Response to Wilms Tumor-1 Protein (WT1). (2004) (5)
- Autoimmune aspects of aplastic anemia. (1988) (5)
- Drug-related blood dyscrasias. Introduction. (1996) (4)
- Viruses and the blood. (1992) (4)
- Telomere Length of peripheral leukocytes is shortened in Ocular Sarcoidosis patients (2013) (4)
- Parvovirus B19 Infection (1997) (4)
- Faculty Opinions recommendation of Association between telomere length in blood and mortality in people aged 60 years or older. (2012) (4)
- Erratum: Recombinant adeno-associated virus (rAAV)-mediated expression of a human γ-globin gene in human progenitor-derived erythroid cells (Proceedings of the National Academy of Science of the United States of America (October 1, 1994) 91:21 (10183-10187)) (1995) (4)
- SARS-CoV-2 infection associated with aplastic anemia and pure red cell aplasia (2022) (4)
- Suppression of Cyclin D 1 (CD1) by on 01910.Na Is Associated with Decreased Survival or Trisomy 8 Myelodysplastic Bone Marrow: A Potential Targetted Therapy for Trisomy 8 MDS. (2008) (4)
- FOXP3-Positive Regulatory T-Cells in Acquired Aplastic Anemia. (2006) (4)
- A novel homozygous RTEL1 variant in a consanguineous Lebanese family: phenotypic heterogeneity and disease anticipation (2019) (4)
- Very Short Telomeres of Peripheral Blood Leukocytes Precede Clinical Progression to Myelodysplasia with Monosomy 7 in Aplastic Anemia Patients (2012) (4)
- The Enigma of the Aplastic Anemia/PNH Syndrome (2003) (4)
- Evidence for T-Cell Oligoclonal Expansion in Aplastic Anemia Associated with Telomerase Complex Mutations: Pathophysiological and Clinical Implications. (2005) (4)
- Allogeneic transplantation using CD34+ selected peripheral blood progenitor cells combined with non‐mobilized donor T cells for refractory severe aplastic anaemia (2017) (4)
- Absence of SBDS mutations in sporadic paediatric acute myeloid leukaemia (2013) (4)
- Whole transcriptome sequencing identifies increased CXCR2 expression in PNH granulocytes (2017) (4)
- PTPN22 620W allele is not associated with aplastic anemia (2007) (4)
- Utility of plasma cell-free DNA for de novo detection and quantification of clonal hematopoiesis (2021) (4)
- A Pilot Study Of Rituximab In Patients With Moderate Aplastic Anemia, Diamond-Blackfan Anemia and Pure Red Cell Aplasia (2013) (4)
- Clonal Evolution In Aplastic Anemia Is Driven By Chromosomal Instability Rather Than Mutations In Myeloid Malignancy Candidate Gene (2013) (4)
- Interphase Chromosome Flow-FISH. (2012) (4)
- Cyclosporine Taper Does Not Prevent Relapse in Severe Aplastic Anemia (2011) (4)
- Clinical and Genetic Heterogeneity of Telomere Diseases. (2012) (4)
- Granulocyte Colony Stimulating Factor Preferentially Causes Proliferation of Pre-Existing Monosomy 7 Cells in Aplastic Anemia and Myelodysplastic Syndrome Because of Abnormal Truncated GCSF-Receptors on These Cells. (2004) (3)
- Comparative Transcriptomic Analysis of the Hematopoietic System between Human and Mouse by Single Cell RNA Sequencing (2021) (3)
- The Thrombopoietin Receptor Agonist Eltrombopag Has DNA Repair Activity in Human Hematopoietic Stem and Progenitor Cells (2015) (3)
- 50 Years of Seminars in Hematology (2013) (3)
- OP04 Safety and efficacy of the terminal complement inhibitor eculizumab in patients with paroxysmal nocturnal hemoglobinuria: Shepherd Phase III clinical study results (2007) (3)
- Prospects for a human B19 parvovirus vaccine (1994) (3)
- Circulating Cytokine Profiles of Patients with Acquired Aplastic Anemia and Myelodysplastic Syndrome (2008) (3)
- Fluorescent Cell Barcoding As New Flow Cytometric Technique for Multiplexed Phenotyping and Signaling Profiling in Hematologic Patients (2016) (3)
- 5-AZACYTIDINE FOR BETA-THALASSAEMIA? (1983) (3)
- High Frequency of Circulating CD8+ Memory Stem T Cells in Acquired Aplastic Anemia (2015) (3)
- Genetic and transcriptional analysis of spindle checkpoint genes in bone marrow failure patients. (2003) (3)
- Dnmt3a-null hematopoietic progenitor stem cells expand after busulfan treatment. (2020) (3)
- Pathogenesis of Parvovirus-induced Disease in Humans (1986) (3)
- 56 ELTROMBOPAG FOR LOW TO INTERMEDIATE-2 RISK MYELODYSPLASTIC SYNDROME (2015) (3)
- Bone Marrow as a Source of Cells for Paroxysmal Nocturnal Hemoglobinuria Detection (2018) (3)
- Significant Disease Burden in Paroxysmal Nocturnal Hemoglobinuria Patients with Lower Levels of Hemolysis, Mild Anemia and Minimal Transfusion: Clinical Improvement with Eculizumab Therapy. (2007) (3)
- PD-1 deficiency augments bone marrow failure in a minor-histocompatibility antigen mismatch lymphocyte infusion model. (2018) (3)
- Sex Hormones Modulate the Length of Telomeres of Normal and Telomerase-Mutant Leukocytes through the Estrogen Receptor Pathway. (2006) (3)
- Paroxysmal nocturnal hemoglobinuria: new insights from murine Pig-a-deficient hematopoiesis. (1997) (3)
- A Murine Model of Bone Marrow Failure Mediated by Disparity in Minor Histocompatibility Antigens. (2005) (3)
- RMRP mutations in hematological disorders (2007) (3)
- Marked Improvement in Short- and Long-Term Survival in Severe Aplastic Anemia Patients Treated with Immunosuppression in the Past 18 Years. (2007) (3)
- Successful Treatment of a Diamond-Blackfan Anemia (DBA) Patient with Eltrombopag (2016) (3)
- Sequencing and characterization of A-2 plaque virus: A new member of the Picornaviridae family. (2000) (3)
- High Resolution Mass Cytometry (CyTOF) in Aplastic Anaemia (AA) Can Identify an Aberrant Treg Subset with Pro-Inflammatory Properties, Predicting Poor Response to Immunosuppressive Therapy (2014) (3)
- Minimal role of interleukin 6 and toll-like receptor 2 and 4 in murine models of immune-mediated bone marrow failure (2021) (2)
- Durable Engraftment and Long-Term Survival Following Fludarabine-Based Nonmyeloablative Hematopoietic Cell Transplantation (HCT) in Patients with ATG-Refractory Severe Aplastic Anemia (SAA) and Other Nonmalignant Hematological Disorders. (2004) (2)
- Eltrombopag Improves Hematopoiesis in Patients with Low to Intermediate-2 Risk Myelodysplastic Syndrome (MDS) (2018) (2)
- High-dose cyclophosphamide for treatment of aplastic anemia. (2002) (2)
- Telomere Shortening and Genomic Instability: Primary Cells from Patients with Telomere Repair Complex Mutations Are Susceptible to End-to-End Chromosome Fusion and Aneuploidy. (2006) (2)
- A Large Mennonite Family with a Novel K570N TERT Gene Mutation: Association with a Clinical Spectrum of Bone Marrow Failure, Acute Myeloid Leukemia, and Acute Liver Failure. (2006) (2)
- Low Morbidity but Prolonged Viral Shedding Characterize Parainfluenza Virus 3 Infections in Allogeneic Peripheral Stem Cell Transplant Recipients. (2004) (2)
- Epidemiology and pathology of erythroviruses. (2000) (2)
- [Hypoproliferative disorders of stem cells]. (1997) (2)
- Epstein-Barr Virus and Risk of Multiple Sclerosis—Reply (2003) (2)
- Purification of functional recombinant YY1 expressed in Sf9 insect cells. (1995) (2)
- Predicting Response and Survival for Severe Aplastic Anemia Patients Treated with Immunosuppression. (2007) (2)
- Aplastic anemia : stem cell biology and advances in treatment : proceedings of the Third International Conference on Aplastic Anemia, held in Airlie, Virginia, June 26-28, 1983 (1984) (2)
- Vaccine Design Informed by Virus-Induced Immunity. (2020) (2)
- JAK2 Inhibition with TG101348 Inhibits Monosomy 7 Myelodysplastic Syndromes (MDS) Bone Marrow Cells In Vitro: a Potential Targeted Therapy for Monosomy 7 MDS (2010) (2)
- 13. Acquired Aplastic Anaemia (2010) (2)
- Does a Chronic Inflammatory Process Underlie Clonal Progression In Aplastic Anemia?- In Vitro and In Vivo Evidence That Inflammation Produces Aneuploidy for Chromosomes 7 and 8 In Replicating Cells (2010) (2)
- VIRUS VIRULENCE AND PATHOGENICITY (1960) (2)
- Message from the new editors (2000) (2)
- Why Current Publication May Distort Science (2008) (2)
- Spectrum Of Genetic Alterations In Acquired Aplastic Anemia (2013) (2)
- Excellent Outcomes of Combined Haploidentical and Cord-Blood (Haplo-Cord) Transplantation and HLA-Matched Sibling (Matched-Sib) Donor Transplantation for High-Risk Patients with Severe Aplastic Anemia (SAA) Refractory to Immunosuppressive Therapy (2016) (2)
- Sirolimus augments hematopoietic stem and progenitor cell regeneration following hematopoietic insults (2020) (2)
- Acquired Aplastic Anemia: New Genetics, New Genomics (2014) (2)
- Androgen Treatment Mitigates Hematopoietic Cell Telomere Attrition In Vivo (2012) (2)
- T Cell Landscape of Immune Aplastic Anemia Reveals a Convergent Antigen-Specific Signature (2019) (2)
- Characterization of autoreactive T-cells in aplastic anemia (2000) (2)
- Human Parvovirus B19 (Preliminary Pages) (1997) (2)
- Long Term Outcome of Pediatric Patients with Severe Aplastic Anemia Treated with Anti-Thymocyte Globulin and Cyclosporine. (2007) (2)
- 1 Viruses, virulence and pathogenicity (1995) (2)
- Novel Surrogate Neutralizing Assay Supports Parvovirus B19 Vaccine Development for Children with Sickle Cell Disease (2021) (2)
- Cytotoxic CD8 T Cell Immune Responses to Wilms Tumor Protein (WT-1) Characterizes Immunosuppression-Responsive Myelodysplasia (MDS). (2006) (1)
- Review in translational hematology Diagnosis and management of paroxysmal nocturnal hemoglobinuria (2005) (1)
- Myelodysplasia in the setting of paroxysmal nocturnal hemoglobinuria: Interpretation of blast percentage in a marrow with erythroid hyperplasia (2020) (1)
- Mitochondrial DNA (mtDNA) Sequence Heterogeneity among and within Single Human CD34 Cells, T Cells, B Cells and Granulocytes. (2004) (1)
- Faculty Opinions recommendation of [Principle of marginotomy in template synthesis of polynucleotides]. (2012) (1)
- The human parvovirus and in vitro hematopoietic colony formation. (1984) (1)
- Viruses as Agents of Haematological Disease (1995) (1)
- Different In Vivo Effects of Horse and Rabbit Antithymocyte Globulin in Patients with Severe Aplastic Anemia (2011) (1)
- Myelodysplastic Syndromes: Immunologic mechanisms and treatment of myelodysplastic syndromes (2005) (1)
- Daclizumab-Associated Erythroderma Is Associated with Rebound Increases in CD25-Positive CD4 Cells Following Treatment of Aplastic Anemia and Pure Red Cell Aplasia. (2005) (1)
- Mutations in the Telomerase Reverse Transcriptase Gene Predisposes to Myelodysplastic Syndromes. (2009) (1)
- Crispr/Cas9-Induced DNMT3A Mutations in the K562 Human Leukemic Cell Line As a Model of DNMT3A-Mutated Leukemogenesis (2016) (1)
- human primary hematopoietic cells gene, increase telomerase activity in TERT Sex hormones, acting on the (2012) (1)
- Seminars Bids Adieu and αντίο to Photis Beris. (2015) (1)
- Spectrum and Clinical Significance of HLA Class I Alleles and Their Somatic Mutations in Immune Aplastic Anemia (2019) (1)
- Comprehensive analysis of single-cell RNA sequencing data from healthy human marrow hematopoietic cells (2020) (1)
- Somatic Mutations in "Benign" Disease. Reply. (2021) (1)
- T-bet Over-Expression in T Cells from Patients with Aplastic Anemia. (2005) (1)
- mouse model of infusion-induced bone marrow failure Bystander destruction of hematopoietic progenitor and stem cells in a (2012) (1)
- Telomere Elongation and Hematologic Improvement in Humans Treated with Androgens: A Prospective Clinical Trial of Danazol in Telomeropathies (2014) (1)
- the treatment of patients with paroxysmal nocturnal hemoglobinuria Multicenter phase 3 study of the complement inhibitor eculizumab for (2008) (1)
- patients with hematological disorders Functional characterization of natural telomerase mutations found in (2013) (1)
- Myeloid Neoplasm Gene Somatic Mutations in Patients with Severe Aplastic Anemia Treated with Eltrombopag and Standard Immunosuppression (2016) (1)
- Paroxysmal nocturnal hemoglobinuria and the glycosylphosphatidylinositol-linkted proteins (2000) (1)
- Ultra-Low Dose IL-2 Safely Expands Regulatory T Cells and CD56bright NK Cells in Healthy Volunteers: Towards Safer Stem Cell Donors? (2012) (1)
- Persistent Elevation of Plasma Thrombopoietin Levels in Severe Aplastic Anemia, Even with Hematologic Recovery (2015) (1)
- Crispr/Cas9-Mediated ASXL1knockout in U937 Human Leukemic Cells Perturbs Myeloid Differentiation (2016) (1)
- Altered microRNAs in T Cells from Patients with Acquired Aplastic Anemia (2014) (1)
- Somatic Mutations in a Single Residue of UBA1 Cause Vexas, a Severe Adult-Onset Rheumatic Disease Associated with Myeloid Dysplasia (2020) (1)
- PARVOVIRUS B19 INFECTION AND HEMATOPOISIS (1995) (1)
- Decreased TCR ζ-Chain Expression in T Cells from Patients with Aplastic Anemia. (2005) (1)
- Human serum sickness. (1984) (1)
- Safety and efficacy of eculizumab with concomitant erythropoietin therapy in patients with paroxysmal nocturnal hemoglobinuria (PNH) (2007) (1)
- Telomere Shortening Promotes Chromosomal Instability and Predicts Malignant Clonal Evolution in Aplastic Anemia. (2009) (1)
- Immunosuppressive Treatment for Patients with Myelodysplastic Syndromes: A Review of 358 Patients (2011) (1)
- Human Immunodeficiency Virus Type 1 Protease Inhibitor Modulates Activation of Peripheral Blood CD 4 1 T Cells and Decreases Their Susceptibility to Apoptosis In Vitro and In Vivo (1999) (1)
- Response: EBV reactivation in the immunosuppressed: to treat or not to treat? (2007) (1)
- Induction of nitric oxide synthase in Fas-mediated apoptosis in hematopoietic cells (1996) (1)
- Higher Mutation Rate in Patients with Aplastic Anemia Using Peripheral Blood cfDNA As Compared with Bone Marrow Cells (2016) (1)
- Mutations in TERT, the Gene Encoding Telomerase Reverse Transcriptase, in “Acquired” Aplastic Anemia Inhibit Enzymatic Function by a Dominant Negative Mechanism of Action. (2004) (1)
- Hemoglobin switching in sheep: only the gamma gene is in the active conformation in fetal liver but all the beta and gamma genes are in the active conformation in bone marrow. (1978) (1)
- Viruses and bone marrow failure. (1991) (1)
- TTV Viremia Is Common in Healthy American and Vietnamese Children (1999) (1)
- Clonally-Restricted T-Lymphocytes in PigA Mutant Mice. (2008) (1)
- Single-Cell RNA-Seq Reveals the Differentiation Hierarchy of Normal Human Bone Marrow and a Distinct Transcriptome Signature of Monosomy 7 Cells (2016) (1)
- Cloning and molecular characterization of telomerase reverse transcriptase (TERT) and telomere length analysis of Peromyscus leucopus. (2015) (1)
- Somatic Mutations and Clonal Hematopoiesis in Aplastic Anemia. (2015) (1)
- Bone marrow skeletal stem / progenitor cell defects in patients with dyskeratosis congenita and telomere biology disorders (2014) (1)
- Alemtuzumab Is Safe and Associated With High Response Rates In Selected Patients With Myelodysplastic Syndrome (2013) (1)
- Heterozygous RTEL1 variants in Patients with Bone Marrow Failure Associate with Telomere Dysfunction in the Absence of Telomere Shortening (2016) (1)
- Lin−CD117+ Hematopoietic Cells Preferentially Home to Spleen and Their Migration Is Affected by Selectins. (2005) (1)
- Regulatory T Cells Immunosuppression and the Infusion of Anemia Is Ameliorated by Minor Antigen H 60-Mediated Aplastic (2007) (1)
- Towards Improved Decision-Making Based on Genomics in Bone Marrow Failure (2018) (1)
- 18 CANDIDATE GENE MUTATIONS IN ACQUIRED APLASTIC ANEMIA CORRELATION WITH SURVIVAL AND CLONAL EVOLUTION TO MYELODYSPLASTIC SYNDROME (2015) (0)
- Absence of Graft Failure and Excellent Long Term Survival Following Fludarabine-Based Reduced Intensity Hematopoietic Stem Cell Transplantation In Heavily Transfused Patients with ATG-Refractory Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes (2010) (0)
- Telomere Length Recovery Strongly Predicts Overall Survival in Acute Promyelocytic Leukemia (2014) (0)
- Aplastic Anaemia (1971) (0)
- 6 The immune pathophysiology of bone marrow failure and the emergence of clonal hematologic diseases (2007) (0)
- Critical Role of the Th1 Transcription Factor T-Bet in An Animal Model of Immune-Mediated Bone Marrow Failure (2008) (0)
- Faculty Opinions recommendation of Telomere length predicts survival independent of genetic influences. (2012) (0)
- Increased Expression of the Signaling Lymphocyte-Activation Molecule (mSLAM) in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH). (2006) (0)
- Inflammation Caused by Allogeneic Lymphocytes Results in Aneuploidy in Bone Marrow Mononuclear Cells (BMMNC) (2008) (0)
- 62 Selectively depleting host-reactive T cells from peripheral blood stem cell allografts — preliminary results of a feasibility study (2003) (0)
- T Cells Response and Autoantibodies to Human Heat Shock Proteins in Aplastic Anemia Patients. (2005) (0)
- Erosion of Telomeric Single-Stranded Overhang in Patients with Aplastic Anemia Carrying Telomerase Mutations. (2009) (0)
- What Causes Aplastic Anaemia: Results of Transplants from Genetically-Identical Twins (2023) (0)
- Evaluation of risk for development of myeloproliferative disorders, myelodysplastic syndromes, or acute leukemias with long-term eculizumab therapy in paroxysmal nocturnal hemoglobinuria (PNH) patients (2007) (0)
- Pathophysiology of Acquired Bone Marrow Failure (2017) (0)
- Bone Marrow Aspirate Samples Are Equal to Peripheral Blood for the Detection of Paroxysmal Nocturnal Hemoglobinuria (PNH) (2017) (0)
- TO WILMS TUMOR PROTEIN ( WT 1 ) IN MYELODYSPLASIA RESPONSIVE TO IMMUNOSUPPRESSIVE THERAPY ( IST ) (2010) (0)
- The Post-Transplant Day 30 Lymphocyte Count Strongly Correlates with Transplanted Cd34 Dose and Is Predictive for Minimal Residual Disease and Mortality in Patients with Cml Undergoing Allogeneic Stem Cell Transplants from Matched Siblings. (2004) (0)
- Acute and chronic parvovirus infection (2021) (0)
- Expression of cellular receptors for interferon-gamma, tumor necrosis factor-alpha and Fas on BM CD34(+) cells (1995) (0)
- Is there a specific effect of antithymocyte globulin on hematopoiesis (2000) (0)
- promoter TERC Human telomere disease due to disruption of the CCAAT box of the (2012) (0)
- Genetic Variation in TERF1 but Not TERF2 Is Associated with Aplastic Anemia Risk. (2005) (0)
- BONE MARROW FAILURE Bone marrow failure and the telomeropathies (2014) (0)
- The epidemiology of aplastic anemia in Thailand. Commentary (2006) (0)
- Identification and Functional Characterization of Novel Telomerase Variant Alleles in Patients with Bone-Marrow Failure Syndromes (2008) (0)
- Characterization of Novel Natural Mutations in Telomere Binding Protein Factor (TIN2) Identified in Patients with Bone-Marrow Failure Syndromes (2008) (0)
- Effects of Granulocyte Colony Stimulating Factor (G-CSF) On Monosomy 7 Aneuploidy and T Cell Subsets in Healthy Donors. (2009) (0)
- Greenpeace Apology (1996) (0)
- Clinical Infectious Disease: Acute and Chronic Parvovirus Infection (2008) (0)
- This information is current as Anemia Memory Stem Cells in Acquired Aplastic + Disease : High Frequency of Circulating CD 8 Memory Stem T Cells in Autoimmune (2016) (0)
- Long-Term Eltrombopag for Bone Marrow Failure Depletes Total Body Iron (2020) (0)
- Hematological Abnormalities in Aged Telomerase RNA Component Deficient Mice Are Associated with Intestinal Epithelial Degeneration and Bone Marrow Stromal Dysfunction (2012) (0)
- Glycosylphosphatidylinositol-Anchored Protein-Deficient Clone Anemia Is Not Associated With a Selective Proliferative Defect in the Impaired Hematopoiesis in Paroxysmal Nocturnal Hemoglobinuria/Aplastic (2013) (0)
- Plasma Cytokines Associated with Low Platelet Counts in Aplastic Anemia and Immune Thrombocytopenia. (2009) (0)
- Content Vol. 136, 2016 (2016) (0)
- FAS ANTIGEN EXPRESSION ON CD34+ CELLS IS INDUCED BY INTERFERON-GAMMA AND TUMOR-NECROSIS-FACTOR-ALPHA AND POTENTIATES CYTOKINE SUPPRESSION OF HEMATOPOIESIS IN-VITRO. (1994) (0)
- FAS antigen expression on normal and aplastic CD34+ cells. (1996) (0)
- and granulocytes cells, T cells, B cells, + Mitochondrial DNA spectra of single human CD34 (2011) (0)
- Safety and efficacy of eculizumab in paroxysmal nocturnal hemoglobinuria evolving from patients with myelodysplastic syndrome and aplastic anemia (2007) (0)
- anemia Telomere length in leukocyte subpopulations of patients with aplastic (2012) (0)
- Lack of correlation of eculizumab therapy in paroxysmal nocturnal hemoglobinuria (PNH) patients with myeloproliferative disorders, myelodysplastic syndromes, acute leukemias or aplastic anemia with long-term treatment (2008) (0)
- Aplastic Anemia: Pathophysiology and Treatment of immune-mediated (2012) (0)
- Experimental induction of hydrops fetalis with simian parvovirus (1998) (0)
- Utlilizing Mutant Mice To Dissect Immune Bone Marrow Failure: Markedly Reduced Cytotoxicity of Lymphocytes from Fas- and Fas Ligand-Deficient Mice in Lymph Node Cell-Mediated Aplastic Anemia. (2007) (0)
- hemoglobinuria cells after erythrocyte transfusion in paroxysmal nocturnal Transfer of glycosylphosphatidylinositol-anchored proteins to deficient (2004) (0)
- Faculty Opinions recommendation of Sequence variants at the TERT-CLPTM1L locus associate with many cancer types. (2012) (0)
- Single-Cell RNA Sequencing of Healthy Human Marrow Hematopoietic Cells (2019) (0)
- Reduced Regulatory T Cell to Activated T Cell Ratio in a Mouse Model of Immune-Mediated Bone Marrow Failure and Prevention of Aplastic Anemia by Infusion of T Regulatory Cells. (2006) (0)
- A pig-a knock-out model of pnh: rescue of hematopoiesis follows transfer of gpi-anchored proteins (1996) (0)
- Clonal T-cell populations attacking the haematopoietic tissue are responsible for immune-mediated aplastic anemia and pathogenically related marrow failure syndromes (2005) (0)
- Contributors (2012) (0)
- B cell response to parvovirus B19 despite abnormal splenic architecture and cytokine/chemokine profiles in patients and animal models with sickle cell disease (SCD) (2017) (0)
- Plasma cytokines associated with low platelet counts in aplastic anemia and immune thrombocytopenia (2010) (0)
- High-dose cyclophosphamide in aplastic anaemia (2001) (0)
- 1 Diagnosis and Management of Paroxysmal Nocturnal Hemoglobinuria : (2005) (0)
- Sustained long-term quantitative defect in the stem cell compartment despite hematologic recovery in patients with aplastic anemia. (1998) (0)
- Supplementary Material for: Telomere Length Recovery: A Strong Predictor of Overall Survival in Acute Promyelocytic Leukemia (2016) (0)
- The Graft-vs-Host Hematopoietic Effect Generated after Nonmyeloablative Allogeneic Stem Cell Transplantation (NST) Cures Patients with Severe PNH. (2004) (0)
- Excellent Engraftment and Reduced Acute and Chronic Graft Versus Host Disease (GVHD) in ATG-Refractory Severe Aplastic Anemia (SAA) Following Transplantation of a PBSC Allograft Containing CD34+ Selected Cells Combined with Non-Mobilized Donor T-Cells (2014) (0)
- Prospects for the Treatment of Aplastic Anemia (1990) (0)
- No association of specific genotypes of CMV and HHV6 in hepatic tissues of patients with hepatitis-associated aplastic anemia (2001) (0)
- Single-Cell RNA Sequencing Reveals a Distinct Transcriptome Signature of Hematopoiesis in GATA2 Deficiency (2019) (0)
- Fas- and Fas Ligand Rather Than Perforin-Mediated Apoptosis Has a Dominant Role in Target Cell Death in Murine Models of Immune- Mediated Bone Marrow Failure (2008) (0)
- Telomere Biology and Disease (2017) (0)
- Studies of the B19 Virus in Bone Marrow Cell Culture (2018) (0)
- Hematopoiesis in Three-Dimensions: Tissue Architecture of Murine and Human Bone Marrow Visualized to a Depth of 100 Micron by Confocal Microscopy (2008) (0)
- Single Cell RNA Sequencing and V(D)J Profiling of T-Cell Large Granular Lymphocytosis (2018) (0)
- Young complications consult : paroxysmal nocturnal hemoglobinuria and its Blood (2013) (0)
- High-dose cyclophosphamide for treatment of aplastic anemia. Authors' reply (2002) (0)
- Cell Therapy in a Mouse Model of Immune-Mediated Bone Marrow Failure. (2007) (0)
- Deficit of Circulating CD19+CD24hiCD38hi Regulatory B Cells in Severe Aplastic Anemia (2019) (0)
- Anti-K562 monoclonal antibodies that recognize antigens on immature hematopoietic cells. (1983) (0)
- Somatic TERT promoter Mutations in a Broad Spectrum of Telomeropathies (2018) (0)
- 104 Cutaneous manifestations of human serum sickness (1985) (0)
- High-dose cyclophosphamide for treatment of aplastic anemia [6] (multiple letters) (2002) (0)
- Alemtuzumab Achieved Durable Hematologic Response In Heavily Treated T-Large Granular Lymphocytosis Irrespective To STAT3 Mutation Or V-Beta Clone Size (2013) (0)
- Mutation Subjects With the Same Telomerase Natural History of Pulmonary Fibrosis in Two (2011) (0)
- Oligoclonal Expansion of Effector Memory CD8+CD57+ T Cells May Sustain Bone Marrow Destruction in Aplastic Anemia (2016) (0)
- 268 “BENIGN” CLONAL HEMATOPOIESIS IN APLASTIC ANEMIA (2015) (0)
- Measurement of circulating and bone marrow long term culture-initiating cells in myelodysplastic patients. (1998) (0)
- Telomeric Recombination in Lymphocytes Implicates ALT, an Alternative Mechanism for Telomere Length Maintenance, in Normal Human Hematopoietic Cells. (2007) (0)
- Reduced Hematopoietic Stem Cell Function in a Mouse Model with Conditional Pig-a Gene Deletion. (2009) (0)
- In Memoriam: Ernst Richard Jaffé (1925–2008) (2008) (0)
- Serum Sickness and Plasma Cytokine Profiles After Treatment with Antithymocyte Globulin In Severe Aplastic Anemia Patients. (2010) (0)
- Introduction (1996) (0)
- Whole Transcriptome Sequencing Identifies Novel Pathways Associated with Paroxysmal Nocturnal Hemoglobinuria- Increased CXCR2 Expression in PNH Granulocytes (2015) (0)
- Rapamycin Is Highly Effective in a Mouse Model of Immune-Mediated Bone Marrow Failure By Mechanisms Distinct from Cyclosporine (2015) (0)
- Subclinical EBV and CMV Reactivations Commonly Occur Following Antibody-Based Immunosuppressive Regimens for Patients with Severe Aplastic Anemia. (2005) (0)
- TINF2 Mutations In Patients with Aplastic Anemia Result In Low TIN2 Expression In Hematopoietic Cells and Very Short Telomeres. (2010) (0)
- Systemically Administered Hydrocortisone Exerts Differential Effects on B and T Lymphocytes and Natural Killer Cells in Healthy Donors (2011) (0)
- Regulation of hemoglobin switching in sheep: cellular and molecular aspects. (1978) (0)
- Eltrombopag Can Stimulate Trilineage Hematopoiesis In Patients with Refractory Severe Aplastic Anemia (2010) (0)
- A Role for Plasma Urokinase Plasminogen Activator Receptor (uPAR) in Thrombosis in Paroxysmal Nocturnal Hemoglobinuria (PNH). (2004) (0)
- Faculty Opinions recommendation of Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells. (2012) (0)
- Adipocytes and Aplastic Anemia: Peroxisome Proliferator-Activated Receptor-γ (PPAR- γ) Antagonists Attenuate Bone Marrow Failure in an Aplastic Anemia Mouse Model but Not in Radiation Marrow Destruction (2012) (0)
- Regulation of the individual globin genes. (1978) (0)
- Sirolimus Augments Hematopoietic Stem and Progenitor Cell Recovery from Hematopoietic Stress (2018) (0)
- Translocation (8;21) acute myeloid leukemia presenting as severe aplastic anemia (2014) (0)
- Biological and Immunological Characterization of ATG and ALG 712 Blood (2005) (0)
- Favorable Impact of T Cell Depleted PBSCT on Transplant Outcomes Despite Delayed Donor T Cell Engraftment. (2004) (0)
- Parvovirus, Infection and Immunity (1998) (0)
- Eltrombopag for Moderate Aplastic Anemia and Unilineage Cytopenias: Dosing, Long-Term Follow-up, Clonal Evolution and Somatic Mutation Profiling (2018) (0)
- Answer to “Confounding effect of cyclosporine dosing when comparing horse and rabbit antithymocyte globulin in patients with severe aplastic anemia” (2015) (0)
- Immunosuppression for Myelodysplastic Syndrome: Association between a Score Based on Presenting Features and Long-Term Survival. (2004) (0)
- A Longitudinal Analysis of the T-Cell Receptor Vβ Repertoire in Aplastic Anemia Patients at Initial Presentation, Remission, and Relapse. (2005) (0)
- 288 GATA2-ASSOCIATED MYELODYSPLASTIC SYNDROME(MDS) HAS UNIQUE IMMUNOPHENOTYPIC FEATURES THAT DIFFER FROM DE NOVO MDS (2015) (0)
- Hematopoietic growth factors: a summary of their biology in tissue culture, animals, and clinical trials. (1990) (0)
- Clinical and laboratorv studies Cutaneous manifestations of serum sickness patients receiving antithymocyte globulin (1985) (0)
- Very Short Telomeres As a Novel Mechanism Of Donor-Cell Derived Leukemia After Cord Blood Transplantation (2013) (0)
- Differential Gene Expression Profile in the T Cell Compartment Between Classic PNH and Aplastic Anemia/PNH Syndrome. (2009) (0)
- Mono clonal antibodies to k 562 cells inhibit growth of bone marrow progenitors in vitro (1981) (0)
- Immunosuppression and stem cell stimulation to treat AA: clinical and biologic implications (2019) (0)
- Analysis of Cytokine Profiling in Hepatitis-Associated Aplastic Anemia. (2005) (0)
- Acquired Aplastic Anaemia and Paroxysmal Nocturnal Haemoglobinuria (2015) (0)
- Hematopoietic Aging Biomarkers in Peromyscus leucopus Mice (2017) (0)
- Telomere Dynamics in Pluripotent Stem Cells Derived From Patients with Telomere Diseases (2011) (0)
- 46 HIGH FREQUENCY OF GATA2 MUTATIONS IN APLASTIC ANEMIA AND HYPOCELLULAR MYELODYSPLASTIC SYNDROME (2015) (0)
- 5 Telomere biology and the pathogenesis of clonal evolution from bone marrow failure (2009) (0)
- Ex Vivo-Generated CD36 (cid:1) Erythroid Progenitors Are Highly Permissive to Human Parvovirus B19 Replication (cid:1) (2008) (0)
- Determination of LTC-IC numbers in patients with myelodysplastic syndromes (1996) (0)
- Telomere length and premature ovarian insufficiency (2015) (0)
- Comparative Single Cell Transcriptomic Analysis of the Hematopoietic System between Human and Mouse (2019) (0)
- Final Results of the Thai-NHLBI Epidemiological Study of Aplastic Anemia. (2004) (0)
- 5-AZACYTIDINE FOR BETA-THALASSAEMIA? (1983) (0)
- SAP (SH2D1A), the Immunomodulator Deficient in X-Linked Lymphoproliferative Syndrome (XLP), Is Profoundly Decreased in Aplastic Anemia: An Immunologic Link between Constitutional and Acquired Bone Marrow Failure. (2006) (0)
- RabbitATG but not horseATG promotes expansion of functional CD4CD25 high FOXP3 regulatory T cells in vitro (2017) (0)
- Aplastic Anemia and Immunosuppression--Reply (2003) (0)
- Long-Term Follow-up of Reduced Intensity Allogeneic Hematopoietic Stem Cell Transplantation for Severe Paroxysmal Nocturnal Hemoglobinuria (2010) (0)
- Genes Encoding Telomere-Binding Proteins TERF1, TERF2 and TIN2 Are mutated in Patients with Acquired Aplastic Anemia. (2004) (0)
- Agranulocytosis. (1994) (0)
- Clinical Utility of Plasma Cell-Free DNA for Detection and Quantification of Clonal Hematopoiesis (2020) (0)
- Endoplasmic Reticulum Stress Is a Target for Therapy in Paroxysmal Nocturnal Hemoglobinuria. (2009) (0)
- Identification and Characterization of a Novel Parvovirus-Like Virus in Seronegative Hepatitis Patients by Next Generation Sequencing (2012) (0)
- Translocation (8;21) Presenting As Severe Aplastic Anemia (2013) (0)
- Insights into Clonal Relationships of Putative Adaptive Natural Killer Cells (NK) in Humans, Via Mapping of Somatic Piga Mutations in Patients with Paroxysmal Nocturna Hemoglobinuria (PNH) (2015) (0)
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What Schools Are Affiliated With Neal S. Young?
Neal S. Young is affiliated with the following schools:
