Neil Garg
American organic chemist
Neil Garg's AcademicInfluence.com Rankings

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Chemistry
Neil Garg's Degrees
- PhD Chemistry California Institute of Technology
- Bachelors Chemistry New York University
Why Is Neil Garg Influential?
(Suggest an Edit or Addition)According to Wikipedia, Neil K. Garg is currently a Distinguished professor of chemistry and holds the Kenneth N. Trueblood Endowed Chair at the University of California, Los Angeles. Garg's research is focused on the chemical synthesis of organic compounds, with an emphasis on the development of new strategies for the preparation of complex molecules possessing unique structural, biological, and physical properties. His group has made breakthroughs in catalysis, especially strong bond activation of esters and amides using nickel catalysts, and in the understanding and utilization of strained intermediates, such as arynes, cyclic alkynes, and cyclic allenes. His laboratory has completed the total syntheses of many natural products, including welwitindolinones, akuammilines, and tubingensin alkaloids. Garg is a co-Founder of ElectraTect, Inc.,
Neil Garg's Published Works
Published Works
- Nickel-catalyzed cross-couplings involving carbon-oxygen bonds. (2011) (995)
- Conversion of Amides to Esters by the Nickel-Catalyzed Activation of Amide C–N Bonds (2015) (362)
- Cross-coupling reactions of aryl pivalates with boronic acids. (2008) (298)
- Breaking Amides using Nickel Catalysis. (2017) (275)
- Nickel-catalysed Suzuki-Miyaura coupling of amides. (2016) (262)
- Ni- and Fe-Catalyzed Cross-Coupling Reactions of Phenol Derivatives (2013) (257)
- Suzuki-Miyaura coupling of aryl carbamates, carbonates, and sulfamates. (2009) (250)
- Suzuki-Miyaura cross-coupling of aryl carbamates and sulfamates: experimental and computational studies. (2011) (241)
- The first total synthesis of dragmacidin d. (2002) (190)
- The Role of Aryne Distortions, Steric Effects, and Charges in Regioselectivities of Aryne Reactions (2014) (189)
- Indolyne and aryne distortions and nucleophilic regioselectivites. (2010) (178)
- Indolyne experimental and computational studies: synthetic applications and origins of selectivities of nucleophilic additions. (2010) (167)
- A two-step approach to achieve secondary amide transamidation enabled by nickel catalysis (2016) (161)
- Regioselective Reactions of 3,4-Pyridynes Enabled by the Aryne Distortion Model (2012) (156)
- The total synthesis of (+)-dragmacidin F. (2004) (144)
- Total synthesis of oxidized welwitindolinones and (-)-N-methylwelwitindolinone C isonitrile. (2012) (134)
- Nickel-catalyzed amination of aryl carbamates and sequential site-selective cross-couplings. (2011) (132)
- Pyridynes and indolynes as building blocks for functionalized heterocycles and natural products. (2015) (128)
- Nickel-Catalyzed Esterification of Aliphatic Amides. (2016) (123)
- Nickel-catalyzed amination of aryl sulfamates. (2011) (119)
- Total synthesis of (±)-aspidophylline A. (2011) (117)
- Overturning indolyne regioselectivities and synthesis of indolactam V. (2011) (113)
- Total synthesis of (-)-N-methylwelwitindolinone C isothiocyanate. (2011) (112)
- Nickel-Catalyzed Alkylation of Amide Derivatives. (2016) (109)
- Nickel-catalyzed Suzuki-Miyaura couplings in green solvents. (2013) (108)
- Steric effects compete with aryne distortion to control regioselectivities of nucleophilic additions to 3-silylarynes. (2012) (107)
- Nickel-catalyzed amination of aryl sulfamates and carbamates using an air-stable precatalyst. (2012) (106)
- Nickel-Catalyzed Activation of Acyl C-O Bonds of Methyl Esters. (2016) (105)
- Cascade reactions: a driving force in akuammiline alkaloid total synthesis. (2014) (104)
- An interrupted Fischer indolization approach toward fused indoline-containing natural products. (2009) (98)
- Benchtop Delivery of Ni(cod)2 using Paraffin Capsules. (2016) (96)
- Iron-catalyzed alkylations of aryl sulfamates and carbamates. (2012) (91)
- Development of an enantiodivergent strategy for the total synthesis of (+)- and (-)-dragmacidin f from a single enantiomer of quinic Acid. (2005) (88)
- Exploration of the interrupted Fischer indolization reaction. (2010) (87)
- Total Synthesis of the Akuammiline Alkaloid Picrinine (2014) (78)
- Identification and characterization of the chaetoviridin and chaetomugilin gene cluster in Chaetomium globosum reveal dual functions of an iterative highly-reducing polyketide synthase. (2012) (78)
- Elucidation of the concise biosynthetic pathway of the communesin indole alkaloids. (2015) (74)
- Enantioselective Total Syntheses of Akuammiline Alkaloids (+)-Strictamine, (-)-2(S)-Cathafoline, and (-)-Aspidophylline A. (2016) (73)
- An efficient computational model to predict the synthetic utility of heterocyclic arynes. (2012) (73)
- Total synthesis of (-)-sarain A. (2007) (73)
- Nickel‐Catalyzed Cross‐Couplings Involving Carbon—Oxygen Bonds (2011) (71)
- Enabling the use of heterocyclic arynes in chemical synthesis. (2014) (67)
- Indolynes as electrophilic indole surrogates: fundamental reactivity and synthetic applications. (2009) (67)
- Nickel-Catalyzed Suzuki-Miyaura Coupling of Aliphatic Amides. (2018) (67)
- Discovery of Unclustered Fungal Indole Diterpene Biosynthetic Pathways through Combinatorial Pathway Reassembly in Engineered Yeast. (2015) (64)
- Mizoroki-Heck Cyclizations of Amide Derivatives for the Introduction of Quaternary Centers. (2017) (62)
- Cycloadditions of Cyclohexynes and Cyclopentyne (2014) (61)
- Nitrone Cycloadditions of 1,2-Cyclohexadiene. (2016) (61)
- Nickel-Catalyzed Reduction of Secondary and Tertiary Amides. (2017) (60)
- Nickel-catalyzed transamidation of aliphatic amide derivatives† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc01980g (2017) (59)
- EcdGHK are three tailoring iron oxygenases for amino acid building blocks of the echinocandin scaffold. (2013) (57)
- Total syntheses of the elusive welwitindolinones with bicyclo[4.3.1] cores. (2012) (56)
- Expanding the Strained Alkyne Toolbox: Generation and Utility of Oxygen-Containing Strained Alkynes. (2016) (54)
- Activation of C-O and C-N Bonds Using Non-Precious-Metal Catalysis. (2020) (53)
- Nickel-Catalyzed Amination of Aryl Chlorides and Sulfamates in 2-Methyl-THF (2014) (52)
- Cine substitution of arenes using the aryl carbamate as a removable directing group. (2012) (52)
- Concise synthesis of the bicyclic scaffold of N-methylwelwitindolinone C isothiocyanate via an indolyne cyclization. (2009) (50)
- Kinetic Modeling of the Nickel-Catalyzed Esterification of Amides (2017) (50)
- Concise Enantiospecific Total Synthesis of Tubingensin A (2014) (49)
- Efficient synthesis of 2-(trimethylsilyl)phenyl trifluoromethanesulfonate: a versatile precursor to o-benzyne. (2009) (49)
- Total syntheses of indolactam alkaloids (-)-indolactam V, (-)-pendolmycin, (-)-lyngbyatoxin A, and (-)-teleocidin A-2. (2014) (49)
- Collaborative Biosynthesis of Maleimide- and Succinimide-Containing Natural Products by Fungal Polyketide Megasynthases. (2017) (49)
- Diels–Alder cycloadditions of strained azacyclic allenes (2018) (46)
- Generation and regioselective trapping of a 3,4-piperidyne for the synthesis of functionalized heterocycles. (2015) (45)
- Computationally Assisted Mechanistic Investigation and Development of Pd-Catalyzed Asymmetric Suzuki-Miyaura and Negishi Cross-Coupling Reactions for Tetra-ortho-Substituted Biaryl Synthesis. (2018) (45)
- Fischer Indolizations as a Strategic Platform for the Total Synthesis of Picrinine. (2015) (45)
- Total synthesis of (+)-sarain A. (2006) (44)
- P450-Mediated Coupling of Indole Fragments To Forge Communesin and Unnatural Isomers. (2016) (44)
- Computational predictions of substituted benzyne and indolyne regioselectivities. (2015) (44)
- Construction of Quaternary Stereocenters by Nickel-Catalyzed Heck Cyclization Reactions. (2016) (44)
- Why do some Fischer indolizations fail? (2011) (43)
- Indole diterpenoid natural products as the inspiration for new synthetic methods and strategies (2017) (42)
- Enantioselective Nickel-Catalyzed Mizoroki-Heck Cyclizations To Generate Quaternary Stereocenters. (2017) (41)
- Total synthesis of (–)-tubingensin B enabled by the strategic use of an aryne cyclization (2017) (40)
- Expanding the structural diversity of polyketides by exploring the cofactor tolerance of an inline methyltransferase domain. (2013) (40)
- Synthetic chemistry fuels interdisciplinary approaches to the production of artemisinin. (2015) (39)
- Interrupted Fischer indolization approach toward the communesin alkaloids and perophoramidine. (2012) (39)
- A unified synthetic approach to the pyrazinone dragmacidins. (2006) (38)
- A ligand-free solid-supported system for Sonogashira couplings: applications in nucleoside chemistry. (2005) (38)
- Synthesis of (+)-phenserine using an interrupted Fischer indolization reaction. (2012) (38)
- Enantiospecific total synthesis of N-methylwelwitindolinone D isonitrile. (2013) (37)
- Total Synthesis of (−)-N-Methylwelwitindolinone B Isothiocyanate via a Chlorinative Oxabicycle Ring-Opening Strategy (2014) (34)
- Conjugated Trimeric Scaffolds Accessible from Indolyne Cyclotrimerizations: Synthesis, Structures, and Electronic Properties. (2017) (34)
- Enantioselective Total Syntheses of Methanoquinolizidine-Containing Akuammiline Alkaloids and Related Studies. (2018) (33)
- The formal total synthesis of dragmacidin B, trans-dragmacidin C, and cis- and trans-dihydrohamacanthins A (2005) (31)
- A fungal nonribosomal peptide synthetase module that can synthesize thiopyrazines. (2011) (31)
- Engineering the biocatalytic selectivity of iridoid production in Saccharomyces cerevisiae. (2017) (30)
- Quantification of the Electrophilicity of Benzyne and Related Intermediates. (2016) (29)
- Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space (2018) (29)
- Indoles and Indolizidines (2011) (29)
- Ni-Catalyzed Suzuki-Miyaura Cross-Coupling of Aliphatic Amides on the Benchtop. (2020) (28)
- Arynes and Cyclic Alkynes as Synthetic Building Blocks for Stereodefined Quaternary Centers. (2018) (28)
- Palladium-Catalyzed Acetylation of Arenes (2014) (28)
- Cycloadditions of Oxacyclic Allenes and a Catalytic Asymmetric Entryway to Enantioenriched Cyclic Allenes. (2019) (28)
- Chemoenzymatic conversion of amides to enantioenriched alcohols in aqueous medium (2019) (27)
- Nickel-Catalyzed Suzuki–Miyaura Cross-Coupling in a Green Alcohol Solvent for an Undergraduate Organic Chemistry Laboratory (2014) (27)
- Effects of a Modified Dye-Labeled Nucleotide Spacer Arm on Incorporation by Thermophilic DNA Polymerases (2006) (26)
- Synthetic studies inspired by vinigrol. (2010) (22)
- Suzuki—Miyaura Coupling of Aryl Carbamates, Carbonates, and Sulfamates. (2010) (20)
- Synthetic studies pertaining to the 2,3-pyridyne and 4,5-pyrimidyne (2016) (19)
- Treating a Global Health Crisis with a Dose of Synthetic Chemistry (2020) (19)
- Cyclic Alkyne Approach to Heteroatom-Containing Polycyclic Aromatic Hydrocarbon Scaffolds. (2019) (19)
- An enzymatic Alder-ene reaction (2020) (18)
- Enzyme-Catalyzed Intramolecular Enantioselective Hydroalkoxylation. (2017) (18)
- Understanding and ModulatingIndolyne Regioselectivities (2011) (18)
- Intercepting fleeting cyclic allenes with asymmetric nickel catalysis (2020) (17)
- Cyanoamidine Cyclization Approach to Remdesivir’s Nucleobase (2020) (17)
- Synthesis of bis(indole)-1,2,4-triazinones (2005) (15)
- Expanding the ROMP Toolbox: Synthesis of Air-Stable Benzonorbornadiene Polymers by Aryne Chemistry. (2017) (15)
- Heterogeneous reductive isomerization reaction using catalytic Pd/C and H2. (2005) (14)
- Discovery and Total Synthesis of a Bis(Cyclotryptamine) Alkaloid Bearing the Elusive Piperidinoindoline Scaffold. (2020) (14)
- Pardon the Interruption: A Modification of Fischer’s Venerable Reaction for the Synthesis of Heterocycles and Natural Products (2016) (13)
- Thioesterase-Catalyzed Aminoacylation and Thiolation of Polyketides in Fungi. (2019) (13)
- Leveraging Fleeting Strained Intermediates to Access Complex Scaffolds (2021) (12)
- Cell-Free Total Biosynthesis of Plant Terpene Natural Products using an Orthogonal Cofactor Regeneration System. (2021) (12)
- Taming Radical Pairs in the Crystalline Solid State: Discovery and Total Synthesis of Psychotriadine. (2021) (11)
- Understanding and Interrupting the Fischer Azaindolization Reaction. (2017) (11)
- Reductive Arylation of Amides via a Nickel-Catalyzed Suzuki-Miyaura Coupling and Transfer Hydrogenation Cascade. (2020) (10)
- Total Synthesis as a Vehicle for Collaboration. (2019) (10)
- Electrochemical Oxidation of Δ9-Tetrahydrocannabinol: A Simple Strategy for Marijuana Detection. (2020) (10)
- Origins of Endo Selectivity in Diels-Alder Reactions of Cyclic Allene Dienophiles. (2021) (9)
- Safety Assessment of Benzyne Generation from a Silyl Triflate Precursor. (2020) (9)
- Palladium-Catalyzed Annulations of Strained Cyclic Allenes. (2021) (9)
- Base-Mediated Meerwein-Ponndorf-Verley Reduction of Aromatic and Heterocyclic Ketones. (2019) (9)
- Dual Neutral Sphingomyelinase-2/Acetylcholinesterase Inhibitors for the treatment of Alzheimer's disease. (2020) (9)
- Suzuki—Miyaura Cross-Coupling of Aryl Carbamates and Sulfamates: Experimental and Computational Studies. (2011) (9)
- Silyl Tosylate Precursors to Cyclohexyne, 1,2-Cyclohexadiene, and 1,2-Cycloheptadiene. (2020) (9)
- Breaking Amide C-N Bonds in an Undergraduate Organic Chemistry Laboratory. (2019) (9)
- Concise Approach to Cyclohexyne and 1,2-Cyclohexadiene Precursors. (2019) (8)
- Synthesis of diphenylhexatriene by the Pd-catalyzed dimerization of cinnamyl acetate. (2013) (8)
- Nickel-Catalyzed Conversion of Amides to Carboxylic Acids. (2020) (8)
- Total Synthesis of (-)-Strictosidine and Interception of Aryne Natural Product Derivatives "Strictosidyne" and "Strictosamidyne". (2021) (7)
- Synthesis of 8-Hydroxygeraniol. (2018) (7)
- The utility of the classical and oxidative heck reactions in natural product synthesis : Studies directed toward the total synthesis of dragmacidin F (2006) (6)
- From heavy water to heavy aldehydes (2019) (6)
- Enantiospecific Total Synthesis ofN-Methylwelwitindolinone D Isonitrile (2013) (6)
- Spectroscopy 101: A Practical Introduction to Spectroscopy and Analysis for Undergraduate Organic Chemistry Laboratories (2017) (6)
- Empowering Students to Innovate: Engagement in Organic Chemistry Teaching. (2018) (4)
- How organic chemistry became one of UCLA's most popular classes (2019) (4)
- Cycloaddition Cascades of Strained Alkynes and Oxadiazinones. (2021) (4)
- Understanding and Modulating Indolyne Regioselectivities (2012) (4)
- Smart access to 3D structures (2018) (4)
- Generation and Regioselective Trapping of a 3,4‐Piperidyne for the Synthesis of Functionalized Heterocycles. (2015) (4)
- Enantiospecific Total Synthesis of N‐Methylwelwitindolinone D Isonitrile. (2014) (3)
- Cross‐Coupling Reactions of Aryl Pivalates with Boronic Acids. (2009) (3)
- Nickel‐Catalyzed Suzuki–Miyaura Coupling in t‐Amyl Alcohol for the Preparation of 5‐(Furan‐3‐yl)pyrimidine (2016) (3)
- Interception of 1,2-Cyclohexadiene with TEMPO Radical (2021) (3)
- Catalysis in Modern Drug Discovery: Insights from a Graduate Student-Taught Undergraduate Course (2022) (3)
- Total synthesis of lissodendoric acid A via stereospecific trapping of a strained cyclic allene (2023) (3)
- Organic chemistry can sizzle (2017) (2)
- Correction to "Total Synthesis of (-)-Sarain A". (2018) (2)
- Evaluation of the photodecarbonylation of crystalline ketones for the installation of reverse prenyl groups on the pyrrolidinoindoline scaffold (2020) (2)
- A platform for on-the-complex annulation reactions with transient aryne intermediates (2021) (2)
- Synthesis of Fused Indolines by Interrupted Fischer Indolization in a Microfluidic Reactor. (2019) (2)
- Effect of sodium stibogluconate on lipid peroxidation and antioxidant enzyme activity of normal and Leishmania donovani infected golden hamsters (1991) (2)
- Bis(tricyclohexylphosphine)dichloronickel (2010) (2)
- ACS Awards 2017. (2017) (2)
- An Au/Zn‐catalyzed Synthesis of N ‐Protected Indole via Annulation of N ‐Arylhydroxamic Acid and Alkyne (2019) (1)
- From glovebox to benchtop (2019) (1)
- Enabling the Use of Heterocyclic Arynes in Chemical Synthesis (2014) (1)
- Gaming stereochemistry (2022) (1)
- Expanding the Strained Alkyne Toolbox: Generation and Utility of Oxygen‐Containing Strained Alkynes. (2016) (1)
- Correction: Synthetic chemistry fuels interdisciplinary approaches to the production of artemisinin. (2015) (1)
- π-Extension of heterocycles via a Pd-catalyzed heterocyclic aryne annulation: π-extended donors for TADF emitters (2022) (1)
- Merging Metals and Strained Intermediates. (2022) (1)
- Origins of Endo Selectivity in Diels–Alder Reactions of Cyclic Allene Dienophiles (2021) (1)
- Shining a light on amine synthesis (2018) (1)
- Indoles and Indolizidines in Natural Product Synthesis (2012) (1)
- Nickel-Catalyzed Suzuki—Miyaura Coupling of Amides. (2016) (1)
- Toward an Optical and Electrochemical Method for Marijuana Detection: A Simple Electrochemical Oxidation of Δ9-THC (2019) (1)
- The total synthesis of dragmacidins D and F (2005) (1)
- Preparation of 6 H ‐Benzo[c]chromen‐6‐one (2019) (1)
- Cascade Reactions: A Driving Force in Akuammiline Alkaloid Total Synthesis (2015) (1)
- Strained intermediates and chemical education as vehicles for innovation (2020) (0)
- Title page (2017) (0)
- Cycloaddition Cascades of Strained Alkynes and Oxadiazinones (2021) (0)
- Intercepting fleeting cyclic allenes with asymmetric nickel catalysis (2020) (0)
- Total Syntheses of Indolactam Alkaloids (‐)‐Indolactam V (Ia), (‐)‐Pendolmycin (Ib), (‐)‐Lyngbyatoxin A (Ic), and (‐)‐Teleocidin A‐2 (Id). (2014) (0)
- Ni-Catalyzed Cross-Coupling of Aryl Pivalates with ArylboronicAcids (2009) (0)
- Pyridynes and Indolynes as Building Blocks for Functionalized Heterocycles and Natural Products (2015) (0)
- Synthetic Studies Pertaining to the 2,3-Pyridyne and 4,5-Pyrimidyne. (2016) (0)
- Concise Enantiospecific Total Synthesis of Tubingensin A. (2014) (0)
- Synthesis of (±)-Aspidophylline A (2011) (0)
- A symmetry-driven approach toward the total synthesis of dodecahedrane (2022) (0)
- Catalyst-Controlled Annulations of Strained Cyclic Allenes with π-Allylpalladium Complexes. (2023) (0)
- The Formal Total Synthesis of Dragmacidin B, trans‐Dragmacidin C, and cis‐ and trans‐Dihydrohamacanthins A. (2005) (0)
- Synthetic Chemistry Fuels Interdisciplinary Approaches to the Production of Artemisinin (2015) (0)
- Nickel-Catalyzed Activation of Acyl C—O Bonds of Methyl Esters. (2016) (0)
- Facile Reduction of Amides Using Nickel Catalysis: Reduction of 12‐Aminododecanolactam (2019) (0)
- Synthesis of 8‐Hydroxygeraniol (2019) (0)
- PROFILE: Early Excellence in Physical Organic Chemistry (2013) (0)
- Elucidating the molecular programming of a nonlinear nonribosomal peptide synthetase responsible for fungal siderophore biosynthesis (2022) (0)
- Modified McFadyen‐Stevens Reaction for a Versatile Synthesis of Aromatic Aldehydes (2019) (0)
- PURIFICATION AND CHARACTERIZATION OF SUBPOPULATIONS OF EXTRACELLULAR VESICLES FROM AD AND PD BRAIN AND THEIR SUPPRESSION BY NSMASE2 INHIBITORS (2019) (0)
- A Unified Synthetic Approach to the Pyrazinone Dragmacidins (2007) (0)
- Nickel‐Catalyzed Amination of Aryl Carbamates and Sequential Site‐Selective Cross‐Couplings. (2011) (0)
- id natural products as the inspiration for new synthetic methods and strategies (2017) (0)
- A Cannabinoid Fuel Cell Capable of Producing Current by Oxidizing Δ9-Tetrahydrocannabinol. (2022) (0)
- Strain-promoted reactions of 1,2,3-cyclohexatriene and its derivatives. (2023) (0)
- Nickel-Catalyzed Suzuki-Miyaura Coupling of ArylCarbamates, Carbonates, and Sulfamates (2010) (0)
- Suzuki-Miyaura Cross-Coupling of Aryl Carbamatesand Sulfamates (2011) (0)
- Synthesis of (-)-N-MethylwelwitindolinoneC Isothiocyanate (2011) (0)
- Advancing global chemical education through interactive teaching tools (2022) (0)
- Mentoring is more important than ever (2022) (0)
- Synthesis of (-)-Sarain A (2006) (0)
- N-acetyl- beta -D-glucosaminidase activity in lymphoid tissues of Mesocricetus auratus during Leishmania donovani infection (1992) (0)
- Mentoring is more important than ever. (2022) (0)
- Effect of Leishmania donovani infection on the activity of γ-glutamyl transpeptidase in lymphoid tissues of Mesocricetus auratus. (1990) (0)
- Total Synthesis of the Akuammiline Alkaloid Picrinine. (2014) (0)
- Development of an Enantiodivergent Strategy for the Total Synthesis of (+)‐ and (‐)‐Dragmacidin F from a Single Enantiomer of Quinic Acid. (2005) (0)
- Nickel-Catalyzed Cross-Coupling Reactions from Amides (2016) (0)
- Synthetic Studies Inspired by Vinigrol (2010) (0)
- Teaching the Large Lecture (2020) (0)
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