Neil Vasdev
Researcher
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Chemistry
Why Is Neil Vasdev Influential?
(Suggest an Edit or Addition)According to Wikipedia, Neil Vasdev is a Canadian and American radiochemist and expert in nuclear medicine and molecular imaging, particularly in the application of PET. Radiotracers developed by the Vasdev Lab are in preclinical use worldwide, and many have been translated for first-in-human neuroimaging studies. He is the director and chief radiochemist of the Brain Health Imaging Centre and director of the Azrieli Centre for Neuro-Radiochemistry at the Centre for Addiction and Mental Health . He is the Tier 1 Canada Research Chair in Radiochemistry and Nuclear Medicine, the endowed Azrieli Chair in Brain and Behaviour and Professor of Psychiatry at the University of Toronto. Vasdev has been featured on Global News, CTV, CNN, New York Times, Toronto Star and the Globe and Mail for his innovative research program.
Neil Vasdev's Published Works
Published Works
- Tau positron emission tomographic imaging in aging and early Alzheimer disease (2016) (737)
- Validating novel tau positron emission tomography tracer [F‐18]‐AV‐1451 (T807) on postmortem brain tissue (2015) (553)
- Association of In Vivo [18F]AV-1451 Tau PET Imaging Results With Cortical Atrophy and Symptoms in Typical and Atypical Alzheimer Disease (2017) (214)
- Spirocyclic hypervalent iodine(III)-mediated radiofluorination of non-activated and hindered aromatics (2014) (190)
- Radiosynthesis and initial evaluation of [18F]-FEPPA for PET imaging of peripheral benzodiazepine receptors. (2008) (184)
- Tau Positron Emission Tomographic Imaging in the Lewy Body Diseases. (2016) (167)
- Chemistry for Positron Emission Tomography: Recent Advances in 11 C-, 18 F-, 13 N-, and 15 O-Labeling Reactions. (2019) (160)
- Emerging PET Radiotracers and Targets for Imaging of Neuroinflammation in Neurodegenerative Diseases: Outlook Beyond TSPO (2018) (130)
- Chelate-free metal ion binding and heat-induced radiolabeling of iron oxide nanoparticles† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c4sc02778g Click here for additional data file. (2014) (100)
- Flortaucipir tau PET imaging in semantic variant primary progressive aphasia (2017) (83)
- 11CO2 fixation: a renaissance in PET radiochemistry. (2013) (78)
- Pharmacokinetic Evaluation of the Tau PET Radiotracer 18F-T807 (18F-AV-1451) in Human Subjects (2017) (77)
- Mechanistic studies and radiofluorination of structurally diverse pharmaceuticals with spirocyclic iodonium(iii) ylides (2016) (75)
- Sifting through the surfeit of neuroinflammation tracers (2017) (75)
- Kinetic Modeling of the Monoamine Oxidase B Radioligand [11C]SL25.1188 in Human Brain with High-Resolution Positron Emission Tomography (2014) (74)
- A concise radiosynthesis of the tau radiopharmaceutical, [(18) F]T807. (2013) (73)
- Synthesis and application of isocyanates radiolabeled with carbon-11. (2011) (71)
- [11C]CURB: Evaluation of a novel radiotracer for imaging fatty acid amide hydrolase by positron emission tomography. (2011) (70)
- (11)C[double bond, length as m-dash]O bonds made easily for positron emission tomography radiopharmaceuticals. (2016) (64)
- Radiosynthesis of [11C]SL25.1188 via [11C]CO2 fixation for imaging monoamine oxidase B (2011) (60)
- Monoamine Oxidase B Total Distribution Volume in the Prefrontal Cortex of Major Depressive Disorder: An [11C]SL25.1188 Positron Emission Tomography Study. (2019) (60)
- Ortho-Stabilized (18) F-Azido Click Agents and their Application in PET Imaging with Single-Stranded DNA Aptamers. (2015) (58)
- 18 F-Labeling of Sensitive Biomolecules for Positron Emission Tomography. (2017) (56)
- Iodonium Ylide–Mediated Radiofluorination of 18F-FPEB and Validation for Human Use (2015) (56)
- 18F-Labeled Single-Stranded DNA Aptamer for PET Imaging of Protein Tyrosine Kinase-7 Expression (2015) (56)
- Synthesis and ex vivo evaluation of carbon-11 labelled N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea ([11C]AR-A014418): a radiolabelled glycogen synthase kinase-3beta specific inhibitor for PET studies. (2005) (55)
- Discovery of a Highly Selective Glycogen Synthase Kinase-3 Inhibitor (PF-04802367) That Modulates Tau Phosphorylation in the Brain: Translation for PET Neuroimaging. (2016) (54)
- Radiolabeled Small Molecule Protein Kinase Inhibitors for Imaging with PET or SPECT (2010) (51)
- Direct fixation of [(11)C]-CO(2) by amines: formation of [(11)C-carbonyl]-methylcarbamates. (2010) (50)
- Recent developments on PET radiotracers for TSPO and their applications in neuroimaging (2020) (48)
- Synthesis and preliminary PET imaging of 11C and 18F isotopologues of the ROS1/ALK inhibitor lorlatinib (2017) (44)
- Synthesis and Preclinical Evaluation of Sulfonamido-based [11C-Carbonyl]-Carbamates and Ureas for Imaging Monoacylglycerol Lipase (2016) (44)
- Engineered antibodies: new possibilities for brain PET? (2019) (42)
- Enzyme-Mediated Modification of Single-Domain Antibodies for Imaging Modalities with Different Characteristics. (2016) (41)
- Synthesis of 6-acrylamido-4-(2-[18F]fluoroanilino)quinazoline: a prospective irreversible EGFR binding probe (2004) (40)
- Alternative approaches for PET radiotracer development in Alzheimer's disease: imaging beyond plaque. (2014) (39)
- Radiosynthesis and Evaluation of [11C-Carbonyl]-Labeled Carbamates as Fatty Acid Amide Hydrolase Radiotracers for Positron Emission Tomography (2012) (38)
- Novel Fluorinated 8-Hydroxyquinoline Based Metal Ionophores for Exploring the Metal Hypothesis of Alzheimer's Disease. (2015) (38)
- Development of new radiopharmaceuticals for imaging monoamine oxidase B. (2011) (38)
- Microfluidic continuous-flow radiosynthesis of [18F]FPEB suitable for human PET imaging. (2014) (37)
- Classics in Neuroimaging: Development of PET Tracers for Imaging Monoamine Oxidases. (2019) (36)
- A Facile Radiolabeling of [18F]FDPA via Spirocyclic Iodonium Ylides: Preliminary PET Imaging Studies in Preclinical Models of Neuroinflammation. (2017) (34)
- In Vitro and in Vivo Evaluation of 11C-Labeled Azetidinecarboxylates for Imaging Monoacylglycerol Lipase by PET Imaging Studies. (2018) (34)
- PET radiopharmaceuticals for probing enzymes in the brain. (2013) (34)
- Charting the mechanism and reactivity of zirconium oxalate with hydroxamate ligands using density functional theory: implications in new chelate design. (2014) (34)
- Recent Advances in 18F Radiochemistry: A Focus on B-18F, Si-18F, Al-18F, and C-18F Radiofluorination via Spirocyclic Iodonium Ylides (2017) (34)
- Utility of commercial radiosynthetic modules in captive solvent [11C]‐methylation reactions (2009) (33)
- Synthesis of [(11)C]Bexarotene by Cu-Mediated [(11)C]Carbon Dioxide Fixation and Preliminary PET Imaging. (2014) (33)
- Pharmacodynamic Imaging Guides Dosing of a Selective Estrogen Receptor Degrader (2015) (32)
- Radiosynthesis and ex vivo evaluation of [(11)C-carbonyl]carbamate- and urea-based monoacylglycerol lipase inhibitors. (2014) (31)
- Alantolactone selectively ablates acute myeloid leukemia stem and progenitor cells (2016) (31)
- Rapid microfluidic flow hydrogenation for reduction or deprotection of 18F-labeled compounds. (2013) (31)
- First Human Use of a Radiopharmaceutical Prepared by Continuous-Flow Microfluidic Radiofluorination: Proof of Concept with the Tau Imaging Agent [18F]T807 (2014) (30)
- Synthesis of (18) F-Difluoromethylarenes from Aryl (Pseudo) Halides. (2016) (29)
- Towards the preparation of radiolabeled 1-aryl-3-benzyl ureas: Radiosynthesis of [(11)C-carbonyl] AR-A014418 by [(11)C]CO(2) fixation. (2012) (29)
- Translocator Protein Distribution Volume Predicts Reduction of Symptoms During Open-Label Trial of Celecoxib in Major Depressive Disorder (2020) (29)
- Synthesis and PET imaging studies of [18F]2-fluoroquinolin-8-ol ([18F]CABS13) in transgenic mouse models of Alzheimer's disease (2012) (28)
- Synthesis and preclinical evaluation of [11C-carbonyl]PF-04457845 for neuroimaging of fatty acid amide hydrolase. (2013) (26)
- Development and characterization of a promising fluorine-18 labelled radiopharmaceutical for in vivo imaging of fatty acid amide hydrolase. (2013) (25)
- Development of new carbon-11 labelled radiotracers for imaging GABAA- and GABAB-benzodiazepine receptors. (2012) (24)
- [11C]Cyanation of arylboronic acids in aqueous solutions. (2017) (24)
- On the preparation of fluorine-18 labelled XeF(2) and chemical exchange between fluoride ion and XeF(2). (2002) (23)
- Is desire for social relationships mediated by the serotonergic system in the prefrontal cortex? An [18F]setoperone PET study (2010) (23)
- Syntheses and in vitro evaluation of fluorinated naphthoxazines as dopamine D2/D3 receptor agonists: radiosynthesis, ex vivo biodistribution and autoradiography of [(18)F]F-PHNO. (2007) (22)
- cGMP production of the radiopharmaceutical [18 F]MK-6240 for PET imaging of human neurofibrillary tangles. (2017) (22)
- C(sp³)-¹⁸F bond formation by transition-metal-based [¹⁸F]fluorination. (2014) (22)
- Design, Synthesis, and Evaluation of Reversible and Irreversible Monoacylglycerol Lipase Positron Emission Tomography (PET) Tracers Using a "Tail Switching" Strategy on a Piperazinyl Azetidine Skeleton. (2019) (22)
- Preparation, characterization, and screening of a high affinity organometallic probe for α-adrenergic receptors. (2011) (21)
- PET of Signal Transduction Pathways in Cancer (2012) (21)
- Replicating predictive serum correlates of greater translocator protein distribution volume in brain (2019) (21)
- On the consensus nomenclature rules for radiopharmaceutical chemistry - Reconsideration of radiochemical conversion. (2020) (21)
- PET neuroimaging studies of [(18)F]CABS13 in a double transgenic mouse model of Alzheimer's disease and nonhuman primates. (2015) (21)
- Total Radiosynthesis: Thinking outside "the box". (2015) (20)
- Synthesis and preliminary biological evaluations of [18F]-1-deoxy-1-fluoro-scyllo-inositol. (2009) (20)
- Evaluating the accuracy of density functional theory for calculating 1H and 13C NMR chemical shifts in drug molecules (2015) (20)
- Metabolic stability of 6,7-dialkoxy-4-(2-, 3- and 4-[18F]fluoroanilino)quinazolines, potential EGFR imaging probes. (2011) (19)
- Positron Emission Tomography Imaging of the Endocannabinoid System: Opportunities and Challenges in Radiotracer Development. (2020) (19)
- Facile 18F labeling of non-activated arenes via a spirocyclic iodonium(III) ylide method and its application in the synthesis of the mGluR5 PET radiopharmaceutical [18F]FPEB (2019) (19)
- "In-loop" [11 C]CO2 fixation: Prototype and proof of concept. (2018) (18)
- Radiosynthesis, In Vitro and In Vivo Evaluation of [18F]CBD-2115 as a First-in-Class Radiotracer for Imaging 4R-Tauopathies. (2021) (18)
- Selected PET Radioligands for Ion Channel Linked Neuroreceptor Imaging: Focus on GABA, NMDA and nACh Receptors. (2016) (18)
- Development of [18F]Maleimide-Based Glycogen Synthase Kinase-3β Ligands for Positron Emission Tomography Imaging. (2017) (17)
- PET Imaging of Fatty Acid Amide Hydrolase with [18F]DOPP in Nonhuman Primates (2014) (17)
- Improving PET Imaging Acquisition and Analysis With Machine Learning: A Narrative Review With Focus on Alzheimer's Disease and Oncology (2019) (17)
- Synthesis of 18F-Arenes from Spirocyclic Iodonium(III) Ylides via Continuous-Flow Microfluidics. (2015) (17)
- Brain Penetration of the ROS1/ALK Inhibitor Lorlatinib Confirmed by PET (2017) (17)
- An improved radiosynthesis of the muscarinic M2 radiopharmaceutical, [18F]FP-TZTP. (2009) (17)
- [18F]Fluoroamines via ring-opening of N-Cbz-2-methylaziridine with [18F]-fluoride (2009) (17)
- Radiosynthesis and ex vivo evaluation of [(18)F]-(S)-3-(6-(3-fluoropropoxy)benzo[d]isoxazol-3-yl)-5-(methoxymethyl)oxazolidin-2-one for imaging MAO-B with PET. (2015) (16)
- Radiosynthesis and preliminary PET evaluation of (18)F-labeled 2-(1-(3-fluorophenyl)-2-oxo-5-(pyrimidin-2-yl)-1,2-dihydropyridin-3-yl)benzonitrile for imaging AMPA receptors. (2016) (16)
- Regioselective ring opening of 2-methylaziridine derivatives with 18F- and 19F-fluoride (2011) (16)
- Radiochemical and NMR spectroscopic investigation of the solvent effect on the electrophilic elemental fluorination of L-DOPA: synthesis of []5-fluoro-L-DOPA (1999) (15)
- Comparisons of [18F]-1-deoxy-1-fluoro-scyllo-inositol with [18F]-FDG for PET imaging of inflammation, breast and brain cancer xenografts in athymic mice. (2011) (15)
- Discovery of PET radiopharmaceuticals at the academia-industry interface. (2017) (14)
- Structural Basis for Achieving GSK-3 Inhibition with High Potency, Selectivity and Brain Exposure for PET Imaging and Drug Discovery. (2019) (14)
- Metal-free 18F-labeling of aryl-CF2H via nucleophilic radiofluorination and oxidative C-H activation. (2016) (13)
- Positron-emission tomography imaging of the TSPO with [(18)F]FEPPA in a preclinical breast cancer model. (2013) (13)
- Synthesis and Reactivity of 18F-Labeled α,α-Difluoro-α-(aryloxy)acetic Acids. (2017) (13)
- Synthesis and preclinical evaluation of [18F]FSL25.1188, a reversible PET radioligand for monoamine oxidase-B. (2019) (13)
- NMR spectroscopic evidence for the intermediacy of XeF(3)(-) in XeF(2)/F(-) exchange, attempted syntheses and thermochemistry of XeF(3)(-) salts, and theoretical studies of the XeF(3)(-) anion. (2010) (13)
- Cognitive impairment and World Trade Centre-related exposures (2021) (12)
- Classics in Neuroimaging: Imaging the Dopaminergic Pathway with PET. (2017) (12)
- In Vitro Evaluation of [3H]CPPC as a Tool Radioligand for CSF-1R. (2021) (12)
- Synthesis and Preliminary PET Imaging Studies of a FAAH Radiotracer ([¹¹C]MPPO) Based on α-Ketoheterocyclic Scaffold. (2016) (12)
- Synthesis and Preclinical Evaluation of [18F]FCHC for Neuroimaging of Fatty Acid Amide Hydrolase (2015) (11)
- Isoflurane increases both the specific binding ratio and sensitivity to amphetamine challenge of [11C]-(+)-PHNO (2006) (10)
- The effect of aromatic fluorine substitution in l-DOPA on the in vivo behaviour of [18F]2-, [18F]5- and [18F]6-fluoro-l-DOPA in the human brain☆ (2002) (10)
- Rationally designed PKA inhibitors for positron emission tomography: Synthesis and cerebral biodistribution of N-(2-(4-bromocinnamylamino)ethyl)-N-[11C]methyl-isoquinoline-5-sulfonamide. (2008) (10)
- Radiosynthesis, ex vivo and in vivo evaluation of [11C]preclamol as a partial dopamine D2 agonist radioligand for positron emission tomography (2006) (10)
- Automation of column-switching HPLC for analysis of radiopharmaceuticals and their metabolites in plasma (2013) (9)
- Synthesis and preliminary evaluation of [18F]-fluoro-(2S)-Exaprolol for imaging cerebral β-adrenergic receptors with PET (2008) (9)
- Facile radiosynthesis of fluorine-18 labeled beta-blockers. Synthesis, radiolabeling, and ex vivo biodistribution of [18F]-(2S and 2R)-1-(1-fluoropropan-2-ylamino)-3-(m-tolyloxy)propan-2-ol. (2008) (9)
- Metal Protein-Attenuating Compound for PET Neuroimaging: Synthesis and Preclinical Evaluation of [11C]PBT2. (2018) (9)
- First Human Use of a Radiopharmaceutical Prepared by Continuous-Flow Microfluidic Radiofluorination: Proof of Concept with the Tau Imaging Agent [18F]T807. (2014) (9)
- A Workshop on Cognitive Aging and Impairment in the 9/11-Exposed Population (2021) (9)
- Imaging of astrocytes in posttraumatic stress disorder: A PET study with the monoamine oxidase B radioligand [11C]SL25.1188 (2021) (9)
- Fluorinated Adenosine A2A Receptor Antagonists Inspired by Preladenant as Potential Cancer Immunotherapeutics (2017) (9)
- Stereoselective 11C Labeling of a “Native” Tetrapeptide by Using Asymmetric Phase-Transfer Catalyzed Alkylation Reactions (2017) (9)
- Structural Basis for Achieving GSK-3 β Inhibition with High Potency, Selectivity, and Brain Exposure for Positron Emission Tomography Imaging and Drug Discovery (2019) (8)
- Preclinical Evaluation of TSPO and MAO-B PET Radiotracers in an LPS Model of Neuroinflammation. (2021) (8)
- Selectivity of elemental fluorine towards l-tyrosine and l-α-methyltyrosine in acidic media and the syntheses of their []3-fluoro and []3,5-difluoro derivatives (2001) (8)
- Repurposing 11C-PS13 for PET Imaging of Cyclooxygenase-1 in Ovarian Cancer Xenograft Mouse Models (2020) (8)
- The Assay of Enzyme Activity by Positron Emission Tomography (2012) (8)
- The Search for a Subtype-Selective PET Imaging Agent for the GABAA Receptor Complex: Evaluation of the Radiotracer [11C]ADO in Nonhuman Primates (2017) (8)
- Synthesis and in vitro evaluation of derivatives of the β₁-adrenergic receptor antagonist HX-CH 44. (2011) (7)
- Classics in Neuroimaging: Imaging the Endocannabinoid Pathway with PET. (2020) (7)
- Radiosynthesis of a Bruton's Tyrosine Kinase Inhibitor, [11 C]Tolebrutinib, via Palladium-NiXantphos-Mediated Carbonylation. (2020) (7)
- Microfluidic radiosynthesis of [18F]FEMPT, a high affinity PET radiotracer for imaging serotonin receptors (2017) (7)
- Copper(I)-Mediated 11C-Carboxylation of (Hetero)arylstannanes (2020) (7)
- Preclinical PET Neuroimaging of [11C]Bexarotene (2016) (6)
- Revisiting the Radiosynthesis of [18F]FPEB and Preliminary PET Imaging in a Mouse Model of Alzheimer’s Disease (2020) (6)
- A double-blind placebo-controlled trial of minocycline on translocator protein distribution volume in treatment-resistant major depressive disorder (2021) (6)
- Synthesis of the dopamine D2/D3 receptor agonist (+)-PHNO via supercritical fluid chromatography: preliminary PET imaging study with [3-11C]-(+)PHNO (2014) (6)
- Syntheses of [18F]5-fluoro-3-nitro-l-tyrosine (2003) (6)
- Radiosynthesis and in vivo tumor uptake of 2-deoxy-2-[(18)F]fluoro-myo-inositol. (2012) (6)
- Fluorine-18 labelled Ruppert-Prakash reagent ([18F]Me3SiCF3) for the synthesis of 18F-trifluoromethylated compounds. (2021) (6)
- TAU PET USING F18-T807: INITIAL EXPERIENCE IN NORMAL ELDERLY AND AD DEMENTIA (2014) (6)
- In Vitro and In Vivo Evaluation of GSK-3 Radioligands in Alzheimer's Disease: Preliminary Evidence of Sex Differences. (2021) (6)
- The Binding of BF-227-Like Benzoxazoles to Human α-Synuclein and Amyloid β Peptide Fibrils (2018) (5)
- 18F-Labeling of Sensitive Biomolecules for Positron Emission Tomography (2017) (5)
- Radiofluorination of oxazole-carboxamides for preclinical PET neuroimaging of GSK-3. (2021) (5)
- Towards the development of new subtype-specific muscarinic receptor radiopharmaceuticals — Radiosynthesis and ex vivo biodistribution of [18F]3-(4-(2-(2-(2-fluoroethoxy)ethoxy)ethylthio)-1,2,5-thiadiazol-3-yl)-1-methyl-1,2,5,6-tetrahydropyridine (2010) (5)
- "In-loop" 18 F-fluorination: A proof-of-concept study. (2019) (5)
- Training the next generation of radiopharmaceutical scientists. (2020) (5)
- Synthesis, in vitro and in vivo evaluation of 11C-O-methylated arylpiperazines as potential serotonin 1A (5-HT1A) receptor antagonist radiotracers (2020) (5)
- Classics in Neuroimaging: Development of Positron Emission Tomography Tracers for Imaging the GABAergic Pathway. (2020) (5)
- Novel PET Radiotracers with Potential Clinical Applications. (2017) (5)
- Recent applications of a single quadrupole mass spectrometer in 11C, 18F and radiometal chemistry. (2018) (5)
- Synthesis and preliminary evaluation of a 11C-labeled piperidin-4-yl azetidine diamide for imaging monoacylglycerol lipase (2016) (5)
- Design and Prototype of an Automated Column-Switching HPLC System for Radiometabolite Analysis (2016) (4)
- PRODUCTION OF THE P-GLYCOPROTEIN MARKER, [C-11]LOPERAMIDE, IN CLINICALLY USEFUL QUANTITIES (2005) (4)
- Fluorine-18: an untapped resource in inorganic chemistry. (2018) (4)
- Leveraging Open Science Drug Development for PET: Preliminary Neuroimaging of 11C-Labeled ALK2 Inhibitors (2021) (4)
- Radiosynthesis of [11C]Ibrutinib via Pd-Mediated [11C]CO Carbonylation: Preliminary PET Imaging in Experimental Autoimmune Encephalomyelitis Mice (2021) (4)
- Artificial intelligence for molecular neuroimaging (2021) (3)
- Molecular Imaging Studies of Second Messenger Pathways: Looking Deeper than the Membrane (2012) (3)
- Preliminary Evaluations of [11C]Verubulin: Implications for Microtubule Imaging With PET (2021) (3)
- Tau PET imaging in the Lewy body diseases (2017) (3)
- First human use of the tau radiopharmaceutical [18F]T807 by microfluidic flow chemistry (2014) (3)
- N‐(4‐Methoxybenzyl)‐N′‐(5‐nitro‐1,3‐thiazol‐2‐yl)urea (AR‐A014418) (2007) (3)
- A rapid one-step radiosynthesis of [11C]-d-threo-methylphenidate (2011) (3)
- Protein Tyrosine Kinase-7 Expression (2015) (3)
- Target receptor identification and subsequent treatment of resected brain tumors with encapsulated and engineered allogeneic stem cells (2022) (3)
- N-Isopropylbenzamide (2008) (3)
- Ring-opening of non-activated aziridines with [11C]CO2via novel ionic liquids (2022) (2)
- Polyamine based solid CO2 adsorbents for [11C]CO2 purification and radiosynthesis (2022) (2)
- Frontispiece: 18F‐Labeling of Sensitive Biomolecules for Positron Emission Tomography (2017) (2)
- Practical Radiosynthesis and Preclinical Neuroimaging of [11C]isradipine, a Calcium Channel Antagonist (2015) (2)
- Discovery of [11C]PF-367 for neuroimaging of glycogen synthase kinase 3 (2015) (2)
- Radionuclide Imaging for Neuroscience: Current Opinion and Future Directions (2020) (2)
- Pharmacokinetic evaluation of the tau radiotracer [18F]T807 and cerebral binding in a subject with traumatic brain injury (2014) (2)
- N-(4-Methoxyphenyl)-N′-(5-nitro-1,3-thiazol-2-yl)urea (2010) (2)
- Selectivity of Elemental Fluorine Towards L-Tyrosine and L-α-Methyltyrosine in Acidic Media and the Syntheses of Their [18F]3-Fluoro and [18F]3,5-Difluoro Derivatives. (2010) (2)
- (E)-2-(2-Methylcyclohexylidene)hydrazinecarbothioamide (2011) (1)
- Synthetic Approaches Towards a Radiofluorinated Agent for Imaging Alzheimer ’ s Disease (2015) (1)
- Evaluation of a small library of carbamates and ureas, including PF-04457845, as potential imaging agents for fatty acid amide hydrolase (FAAH) (2012) (1)
- Exploratory Assessment of K-means Clustering to Classify 18F-Flutemetamol Brain PET as Positive or Negative (2021) (1)
- Syntheses of Fluorine-18 Labelled Compounds and Radiopharmaceuticals by Electrophilic Fluorination (2003) (1)
- [11C]-URB694 for FAAH PET imaging: A novel radiotracer for a new target (2010) (1)
- PET imaging of Alzheimer’s disease (AD) transgenic mice with a F-18 labeled hydroxy quinoline derivative (2010) (1)
- 18F-Fluoroestradiol PET guides dosing of selective estrogen receptor degraders (2014) (1)
- Evaluation of Tau Radiotracers in Chronic Traumatic Encephalopathy (2022) (1)
- Head-to-Head Comparison of Tau-PET Radioligands for Imaging TDP-43 in Post-Mortem ALS Brain. (2022) (1)
- Characterization of neuroinflammatory positron emission tomography biomarkers in chronic traumatic encephalopathy (2022) (1)
- Recent Developments in Carbon-11 Chemistry and Applications for First-In-Human PET Studies (2023) (1)
- PET imaging of glycogen synthase kinase-3 in pancreatic cancer xenograft mouse models. (2022) (1)
- Ortho -stabilized 18 F-azido click agents and application in PET imaging of single-stranded DNA aptamer (2016) (1)
- Pharmacokinetic analysis of the novel glycogen synthase kinase-3 radioligand [11C]PF367 in non-human primates (2016) (1)
- A one-step radiosynthesis of [11C]methylphenidate (2010) (1)
- Cardiac Sympathetic Positron Emission Tomography Imaging with Meta-[18F]Fluorobenzylguanidine is Sensitive to Uptake-1 in Rats. (2021) (1)
- A New F-18 Labeled PET Agent For Imaging Alzheimer's Plaques (2011) (1)
- PET imaging of early stages of Alzheimer's disease (AD) in transgenic mice with F-18 hydroxy quinoline (2011) (1)
- PET imaging of Alzheimer's disease (AD) transgenic mice with F-18 labeled 8-hydroxy quinoline (2010) (1)
- Classics in Neuroimaging: Development of PET Tracers for Imaging the GABAergic pathway. (2021) (1)
- Assessment of disease progression in Alzheimer's transgenic mice by PET imaging with F-18 quinoline (2012) (0)
- Strategies for designing novel PET radiotracers to cross the blood brain barrier. (2023) (0)
- Development of [ F]Maleimide-Based Glycogen Synthase Kinase-3ß Ligands for Positron Emission Tomography Imaging. (2017) (0)
- A comparative study of the in vivo behaviour of [18F] 2‐, 5‐ and 6‐fluoro‐L‐dopa in the human brain (2001) (0)
- Facile 18F labeling of non-activated arenes via a spirocyclic iodonium(III) ylide method and its application in the synthesis of the mGluR5 PET radiopharmaceutical [18F]FPEB (2019) (0)
- Evaluation of neuroinflammatory radiotracers in chronic traumatic encephalopathy (2022) (0)
- Meet the editors: Neil Vasdev. (2021) (0)
- Application of ionic liquids for ring-opening of non-activated aziridines with [11C]CO2 (2022) (0)
- Synthesis of 3‐[18F]Fluoro‐5‐(2‐Pyridinylethynyl)Benzonitrile ([18F]FPEB) (2015) (0)
- Solid polyamine adsorbents for [11C]CO2 capture, purification, and radiosynthesis (2022) (0)
- PET imaging of AD transgenic mice at an early age with 18F-labeled hydroxyquinoline (2012) (0)
- Radiosynthesis and preclinical evaluation of PBT2 for probing the metal hypothesis of Alzheimer’s disease (2018) (0)
- Classics in Neuroimaging: Development of PET Imaging Agents for Imaging Monoamine Oxidases (2020) (0)
- PET imaging of Alzheimer’s transgenic mice at an early age with F-18 quinoline (2011) (0)
- Synthesis of [11C]bexarotene by [11C]CO2 fixation: Preliminary preclinical imaging in nonhuman primate (2014) (0)
- Synthesis and in vivo evaluation of [18F]CHC for neuroimaging fatty acid amide hydrolase (2014) (0)
- TEMPORAL NEOCORTICAL TAU DEPOSITION MEASURED WITH PET IS ASSOCIATED WITH LONGITUDINAL DECLINE IN MEMORY PERFORMANCE AMONG CLINICALLY NORMAL ELDERLY (2014) (0)
- In Vivo Imaging and Kinetic Modeling of Novel Glycogen Synthase Kinase-3 Radiotracers [11C]OCM-44 and [18F]OCM-50 in Non-Human Primates (2023) (0)
- A simplified radiosynthesis of [18F]FMPEP for imaging CB1 receptors (2022) (0)
- PET/CT imaging of macrophage infiltration in myocardial infarct with 89Zr-Ferumoxytol (2014) (0)
- Aryl-18F Bond Formation from Nucleophilic [18F]fluoride (2020) (0)
- Radiofluorination of Ruppert-Prakash reagent (Me3SiC[18F]F3) for syntheses of 18F-trifluoromethylated compounds (2021) (0)
- Synthesis and preliminary pet imaging of 11C- and 18F-isotopologues of the ROS1/ALK inhibitor PF-06463922 in nonhuman primates (2016) (0)
- Translation of New Chemical Methods and Radiopharmaceuticals for Neuroimaging (2022) (0)
- Repurposing [11C]MC1 for PET Imaging of Cyclooxygenase-2 in Colorectal Cancer Xenograft Mouse Models (2021) (0)
- Preclinical PET imaging of GSK-3 in pancreatic cancer (2022) (0)
- Synthesis of a novel 18F-labeled radioligand for monoamine oxidase-B and preliminary PET imaging in non-human primate (2018) (0)
- EXTH-49. THERAPEUTIC EFFICACY OF ENGINEERED, HYDROGEL ENCAPSULATED BIMODAL MSC IN GLIOBLASTOMA STRATIFIED ON CELL SURFACE RECEPTOR EXPRESSION (2019) (0)
- New detection configuration for low activity levels of PET tracers during the analysis of plasma samples. (2019) (0)
- Imaging tau pathology in vivo in ftld with [18F] T807 PET (2015) (0)
- Efficient synthesis of [18F]-{beta}-blockers: [18F]-S-fluoro-toliprolol and exaprolol (2008) (0)
- PET imaging of 11C-labeled cyclooxygenase-1 (COX-1) and COX-2 radioligands in ovarian, breast, and pancreatic cancer xenograft mouse models. (2020) (0)
- Correction to: Alantolactone selectively ablates acute myeloid leukemia stem and progenitor cells (2021) (0)
- Revisiting [18F]FHMP for imaging MAO-B (2010) (0)
- Multicomponent Reactions in 11 C / 12 C Chemistry – Targeting the Angiotensin II Subtype 2 Receptor (2016) (0)
- Heat-induced, chelate-free radiolabeling of iron-oxide nanoparticles (2014) (0)
- Fluorine-18 labeled hydroxy quinoline derivatives as PET tracers for amyloid plaque imaging (2009) (0)
- Recent advances towards imaging cerebral β-adrenergic receptors with PET (2008) (0)
- Radiopharmaceutical Discovery with 11CO2-Fixation Methods Inspired by Green Chemistry (2021) (0)
- Correction to Preparation, Characterization, and Screening of a High Affinity Organometallic Probe for α-Adrenergic Receptors (2011) (0)
- 4-Bromo-8-methoxyquinoline (2008) (0)
- PET imaging of Alzheimer's transgenic mice at an early age with F-18 quinoline (2011) (0)
- Development of New PET radiopharmaceuticals for imaging monoamine oxidase-B (2010) (0)
- Imaging tau pathology in vivo in FTLD spectrum tauopathies with [18F] T807 PET (I11-5E) (2015) (0)
- Production of Medically Important Radionuclides 52Mn and 90Nb (2019) (0)
- Microfluidic 2-step radiosynthesis of [18F]FEMPT, a high affinity PET radiotracer for 5-HT1AR (2016) (0)
- PET Imaging of Fructose Metabolism in a Rodent Model of Neuroinflammation with 6-[18F]fluoro-6-deoxy-D-fructose (2022) (0)
- Serum amyloid P component (SAP) modulates antidepressant effects through promoting membrane insertion of the serotonin transporter (2022) (0)
- Preclinical evaluation of 11C-JNJ55511118 and 11C-JNJ56022486 for imaging subtype-selective AMPA receptor (2018) (0)
- Radiosynthesis, in vitro and in vivo evaluations of [3H]/[18F]CBD-2115 as first in class radiotracers for imaging 4R-tauopathies (2021) (0)
- Comparison of the tumor and inflammation uptake of [18F]-deoxy-1-fluoro-scyllo-inositol and [18F]-FDG in athymic mice bearing human breast cancer xenografts (2010) (0)
- Editorial: Positron Emission Tomography (PET) Imaging of Brain Biochemistry: Beyond High-Affinity Radioligands (2022) (0)
- Leveraging an open science approach for PET radiotracer discovery: radiolabelling and preliminary neuroimaging of 11C-labelled activin receptor-like kinase 2 inhibitors (2021) (0)
- Catalytic Asymmetric 11C-Labeling of Native Tetrapeptide D-[11C]-Phe-D-Trp-L-Lys-L-Thr-OH as the Essential Pharmacophore for Somatostatin Imaging (2016) (0)
- Synthesis of fluorine-18 labeled glycogen synthase kinase-3 inhibitors and preliminary PET neuroimaging in rodent and non-human primate (2021) (0)
- Selectivity of [18F]F2 towards L‐α‐methyltyrosine and L‐tyrosine: A radiochemical and NMR spectroscopic study (2001) (0)
- New classes of fluorine-18 labelled radiotracers for imaging dementia (2009) (0)
- Practical Synthesis of 18F-Difluoromethylarenes from Aryl Halides (2016) (0)
- Development of [18F]FEMPT, a high affinity PET tracer for 5-HT1AR. (2015) (0)
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