Nenad Sestan
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Why Is Nenad Sestan Influential?
(Suggest an Edit or Addition)According to Wikipedia, Nenad Šestan is Harvey and Kate Cushing Professor of Neuroscience and professor of comparative medicine, genetics and psychiatry at the Yale School of Medicine. He received his MD from the School of Medicine, University of Zagreb in 1995 and his PhD from Yale School of Medicine in 1999.
Nenad Sestan's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- De novo mutations revealed by whole-exome sequencing are strongly associated with autism (2012) (1893)
- Spatiotemporal transcriptome of the human brain (2011) (1683)
- Transcriptional Landscape of the Prenatal Human Brain (2014) (1059)
- Sequence Variants in SLITRK1 Are Associated with Tourette's Syndrome (2005) (959)
- Microarray analysis of microRNA expression in the developing mammalian brain (2004) (806)
- Coexpression Networks Implicate Human Midfetal Deep Cortical Projection Neurons in the Pathogenesis of Autism (2013) (765)
- Satb2 Is a Postmitotic Determinant for Upper-Layer Neuron Specification in the Neocortex (2008) (597)
- Contact-dependent inhibition of cortical neurite growth mediated by notch signaling. (1999) (582)
- Comprehensive functional genomic resource and integrative model for the human brain (2018) (575)
- Functional and Evolutionary Insights into Human Brain Development through Global Transcriptome Analysis (2009) (562)
- Prolonged myelination in human neocortical evolution (2012) (508)
- Whole exome sequencing identifies recessive WDR62 mutations in severe brain malformations (2010) (492)
- Integrative functional genomic analysis of human brain development and neuropsychiatric risks (2018) (464)
- Processing of the notch ligand delta by the metalloprotease Kuzbanian. (1999) (437)
- The Cellular and Molecular Landscapes of the Developing Human Central Nervous System (2016) (424)
- Notch regulates cell fate and dendrite morphology of newborn neurons in the postnatal dentate gyrus (2007) (383)
- Transcriptional co-regulation of neuronal migration and laminar identity in the neocortex (2012) (327)
- Adolescent mental health—Opportunity and obligation (2014) (320)
- Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors (2007) (314)
- The PsychENCODE project (2015) (303)
- The autism-associated chromatin modifier CHD8 regulates other autism risk genes during human neurodevelopment (2015) (289)
- Zfp312 is required for subcortical axonal projections and dendritic morphology of deep-layer pyramidal neurons of the cerebral cortex. (2005) (252)
- Comprehensive cellular‐resolution atlas of the adult human brain (2016) (250)
- SOX5 postmitotically regulates migration, postmigratory differentiation, and projections of subplate and deep-layer neocortical neurons (2008) (240)
- Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia. (2016) (236)
- Evolution of the Human Nervous System Function, Structure, and Development (2017) (232)
- Postnatal Deletion of Numb/Numblike Reveals Repair and Remodeling Capacity in the Subventricular Neurogenic Niche (2006) (215)
- Spatiotemporal transcriptomic divergence across human and macaque brain development (2018) (214)
- Neuregulin 1–erbB2 signaling is required for the establishment of radial glia and their transformation into astrocytes in cerebral cortex (2003) (206)
- Interaction between Reelin and Notch Signaling Regulates Neuronal Migration in the Cerebral Cortex (2008) (202)
- The BRAIN Initiative Cell Census Consortium: Lessons Learned toward Generating a Comprehensive Brain Cell Atlas (2017) (196)
- Genome-wide de novo risk score implicates promoter variation in autism spectrum disorder (2018) (196)
- An analytical framework for whole-genome sequence association studies and its implications for autism spectrum disorder (2018) (194)
- Molecular topography of an entire nervous system (2020) (193)
- Temporal Specification and Bilaterality of Human Neocortical Topographic Gene Expression (2014) (192)
- Transcriptome and epigenome landscape of human cortical development modeled in organoids (2018) (192)
- Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network (2017) (190)
- Early emergence of cortical interneuron diversity in the mouse embryo (2018) (188)
- The γ-secretase-generated intracellular domain of β-amyloid precursor protein binds Numb and inhibits Notch signaling (2002) (188)
- Different mutational rates and mechanisms in human cells at pregastrulation and neurogenesis (2018) (185)
- Mammalian 5′-Capped MicroRNA Precursors that Generate a Single MicroRNA (2013) (183)
- TBR1 directly represses Fezf2 to control the laminar origin and development of the corticospinal tract (2011) (181)
- Evolutionarily Dynamic Alternative Splicing of GPR56 Regulates Regional Cerebral Cortical Patterning (2014) (177)
- Cis-regulatory control of corticospinal system development and evolution (2012) (170)
- Down Syndrome Developmental Brain Transcriptome Reveals Defective Oligodendrocyte Differentiation and Myelination (2016) (164)
- Molecular and cellular reorganization of neural circuits in the human lineage (2017) (162)
- New insights into the development of the human cerebral cortex (2019) (155)
- The Emerging Biology of Autism Spectrum Disorders (2012) (153)
- Midline radial glia translocation and corpus callosum formation require FGF signaling (2006) (150)
- Restoration of brain circulation and cellular functions hours post-mortem (2019) (142)
- Transcriptome Analysis of the Human Striatum in Tourette Syndrome (2016) (137)
- DAWN: a framework to identify autism genes and subnetworks using gene expression and genetics (2014) (125)
- Laminar and Columnar Development of Barrel Cortex Relies on Thalamocortical Neurotransmission (2013) (124)
- Species-Dependent Posttranscriptional Regulation of NOS1 by FMRP in the Developing Cerebral Cortex (2012) (120)
- Targeted DNA Sequencing from Autism Spectrum Disorder Brains Implicates Multiple Genetic Mechanisms (2015) (114)
- Neocortical Networks Entrain Neuronal Circuits in Cerebellar Cortex (2009) (112)
- Spatially Heterogeneous Choroid Plexus Transcriptomes Encode Positional Identity and Contribute to Regional CSF Production (2015) (111)
- The ethics of experimenting with human brain tissue (2018) (110)
- Recessive LAMC3 mutations cause malformations of occipital cortical development (2011) (108)
- The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling. (2002) (103)
- Selective depletion of molecularly defined cortical interneurons in human holoprosencephaly with severe striatal hypoplasia. (2009) (103)
- The developmental transcriptome of the human brain: implications for neurodevelopmental disorders. (2014) (99)
- A Multiregional Proteomic Survey of the Postnatal Human Brain (2017) (97)
- cAMP-PKA phosphorylation of tau confers risk for degeneration in aging association cortex (2014) (96)
- Evolution of Osteocrin as an activity-regulated factor in the primate brain (2016) (91)
- Mutations in LAMB1 cause cobblestone brain malformation without muscular or ocular abnormalities. (2013) (91)
- Independent parcellation of the embryonic visual cortex and thalamus revealed by combinatorial Eph/ephrin gene expression (2001) (85)
- Mutations in KATNB1 Cause Complex Cerebral Malformations by Disrupting Asymmetrically Dividing Neural Progenitors (2014) (85)
- Post-transcriptional regulation of mouse neurogenesis by Pumilio proteins (2017) (83)
- Developmentally regulated and evolutionarily conserved expression of SLITRK1 in brain circuits implicated in Tourette syndrome (2009) (83)
- Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells (2021) (80)
- Lost in Translation: Traversing the Complex Path from Genomics to Therapeutics in Autism Spectrum Disorder (2018) (79)
- A Genomic Perspective (2019) (78)
- Control of species-dependent cortico-motoneuronal connections underlying manual dexterity (2017) (77)
- Nitrinergic neurons in the developing and adult human telencephalon: Transient and permanent patterns of expression in comparison to other mammals (1999) (70)
- Neuronal carbonic anhydrase VII provides GABAergic excitatory drive to exacerbate febrile seizures (2013) (70)
- Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates (2013) (68)
- Whole-Genome and RNA Sequencing Reveal Variation and Transcriptomic Coordination in the Developing Human Prefrontal Cortex (2019) (66)
- Homozygous loss of DIAPH1 is a novel cause of microcephaly in humans (2014) (64)
- The CeNGEN Project: The Complete Gene Expression Map of an Entire Nervous System (2018) (62)
- Coupling diffusion imaging with histological and gene expression analysis to examine the dynamics of cortical areas across the fetal period of human brain development. (2013) (61)
- TSHZ3 deletion causes an autism syndrome and defects in cortical projection neurons (2016) (58)
- Expression profiling of the mature C. elegans nervous system by single-cell RNA-Sequencing (2019) (53)
- Axonal ribosomes and mRNAs associate with fragile X granules in adult rodent and human brains (2017) (52)
- The DGCR5 long noncoding RNA may regulate expression of several schizophrenia-related genes (2018) (52)
- Laminar and temporal expression dynamics of coding and noncoding RNAs in the mouse neocortex. (2014) (51)
- Shared and derived features of cellular diversity in the human cerebral cortex (2019) (51)
- The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing (2021) (50)
- Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus (2020) (50)
- Spatial and cell-type transcriptional landscape of human cerebellar development (2021) (49)
- From trans to cis: transcriptional regulatory networks in neocortical development. (2015) (47)
- The neural EGF family member CALEB/NGC mediates dendritic tree and spine complexity (2007) (43)
- Human neuroepithelial stem cell regional specificity enables spinal cord repair through a relay circuit (2018) (41)
- Rewiring of human neurodevelopmental gene regulatory programs by human accelerated regions (2021) (40)
- Brain malformations associated with Knobloch syndrome--review of literature, expanding clinical spectrum, and identification of novel mutations. (2014) (38)
- Simultaneous dimension reduction and adjustment for confounding variation (2016) (37)
- Revealing the brain's molecular architecture. (2018) (37)
- Regulation of prefrontal patterning and connectivity by retinoic acid (2021) (34)
- EphB receptor forward signaling regulates area-specific reciprocal thalamic and cortical axon pathfinding (2014) (34)
- Population-averaged macaque brain atlas with high-resolution ex vivo DTI integrated into in vivo space (2017) (34)
- The 7q11.23 Protein DNAJC30 Interacts with ATP Synthase and Links Mitochondria to Brain Development (2018) (34)
- Disruptions in asymmetric centrosome inheritance and WDR62-Aurora kinase B interactions in primary microcephaly (2017) (32)
- Spatial mapping of structural and connectional imaging data for the developing human brain with diffusion tensor imaging. (2015) (31)
- Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders (2021) (28)
- Transcriptional priming as a conserved mechanism of lineage diversification in the developing mouse and human neocortex (2020) (26)
- Functional Synergy between Cholecystokinin Receptors CCKAR and CCKBR in Mammalian Brain Development (2015) (25)
- Brain vulnerability and viability after ischaemia (2021) (24)
- The evolution of the human brain and disease susceptibility. (2020) (23)
- Schizophrenia and a high-resolution map of the three-dimensional chromatin interactome of adult and fetal cortex (2018) (23)
- Histochemical localization of nitric oxide synthase in the CNS (1994) (23)
- Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus (2022) (23)
- XSAnno: a framework for building ortholog models in cross-species transcriptome comparisons (2014) (23)
- Modeling the Evolution of Human Brain Development Using Organoids (2019) (22)
- Rare deleterious mutations of the gene EFR3A in autism spectrum disorders (2014) (21)
- Hominini-specific regulation of CBLN2 increases prefrontal spinogenesis (2021) (20)
- Isoform-Level Interpretation of High-Throughput Proteomics Data Enabled by Deep Integration with RNA-seq. (2018) (20)
- Cortical Projection Neurons: Sprung from the Same Root (2013) (19)
- Reciprocal Connections Between Cortex and Thalamus Contribute to Retinal Axon Targeting to Dorsal Lateral Geniculate Nucleus (2018) (19)
- Cellular recovery after prolonged warm ischaemia of the whole body (2022) (19)
- Machine learning reveals bilateral distribution of somatic L1 insertions in human neurons and glia (2019) (17)
- Limited contribution of rare, noncoding variation to autism spectrum disorder from sequencing of 2,076 genomes in quartet families (2017) (16)
- Variation of Human Neural Stem Cells Generating Organizer States In Vitro before Committing to Cortical Excitatory or Inhibitory Neuronal Fates (2019) (16)
- Comprehensive cellular‐resolution atlas of the adult human brain (2017) (16)
- A MARKOV RANDOM FIELD-BASED APPROACH TO CHARACTERIZING HUMAN BRAIN DEVELOPMENT USING SPATIAL-TEMPORAL TRANSCRIPTOME DATA. (2015) (15)
- Evolution and Ontogenetic Development of Cortical Structures (2019) (14)
- Brain ventricles as windows into brain development and disease (2022) (13)
- Compartmentalization of NADPH-diaphorase staining in the developing human striatum (1992) (13)
- RNA-seq analysis of developing olfactory bulb projection neurons (2016) (13)
- Molecular and cellular evolution of the primate dorsolateral prefrontal cortex (2022) (12)
- Dynamic and Cell-Specific DACH1 Expression in Human Neocortical and Striatal Development. (2019) (12)
- Molecular Diversity Among Adult Human Hippocampal and Entorhinal Cells (2020) (12)
- Global and Regional Development of the Human Cerebral Cortex: Molecular Architecture and Occupational Aptitudes. (2020) (11)
- Neural Stem Cells Direct Axon Guidance via Their Radial Fiber Scaffold (2020) (11)
- Differential Gene Expression in the Human Brain Is Associated with Conserved, but Not Accelerated, Noncoding Sequences (2017) (10)
- In silico analysis of the transcriptional regulatory logic of neuronal identity specification throughout the C. elegans nervous system (2021) (10)
- Developmental Dynamics of RNA Translation in the Human Brain (2021) (10)
- Transcriptional repression by FEZF2 restricts alternative identities of cortical projection neurons (2021) (10)
- Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability (2022) (10)
- Regulation of Prefrontal Patterning, Connectivity and Synaptogenesis by Retinoic Acid (2019) (8)
- Disruption of NEUROD2 causes a neurodevelopmental syndrome with autistic features via cell-autonomous defects in forebrain glutamatergic neurons (2021) (7)
- Mutations in KATNB1 Cause Complex Cerebral Malformations by Disrupting Asymmetrically Dividing Neural Progenitors (2015) (7)
- A Markov random field-based approach for joint estimation of differentially expressed genes in mouse transcriptome data (2016) (6)
- Spatial and single-cell transcriptional landscape of human cerebellar development (2020) (6)
- Developmental dynamics of voltage-gated sodium channel isoform expression in the human and mouse brain (2021) (6)
- Disruption of the transcription factor NEUROD2 causes an autism syndrome via cell-autonomous defects in cortical projection neurons (2020) (6)
- Neurobiology: Building a bigger brain (2014) (5)
- Neuronal and glial 3D chromatin architecture illustrates cellular etiology of brain disorders (2020) (5)
- Cux2 expression regulated by Lhx2 in the upper layer neurons of the developing cortex. (2019) (5)
- Zika Virus Disrupts Phosp ho-TBK 1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia Graphical Abstract Highlights (2016) (4)
- A neural stem cell paradigm of pediatric hydrocephalus. (2022) (4)
- Notch Signaling in the Brain: More than Just a Developmental Story (2002) (4)
- Primate-specific response of astrocytes to stroke limits peripheral macrophage infiltration (2020) (4)
- Hominini-Specific Regulation of CBLN2 Increases Prefrontal Synaptogenesis (2019) (3)
- Planar cell polarity pathway and development of the human visual cortex (2018) (2)
- Comprehensive multi-omic profiling of somatic mutations in malformations of cortical development (2023) (2)
- Developmental dynamics of voltage-gated sodium channel isoform expression in the human and mouse neocortex (2020) (2)
- Spatiotemporal and genetic regulation of A-to-I editing throughout human brain development (2022) (2)
- Precursors that Generate aS ingle MicroRNA (2013) (2)
- A cross-species proteomic map of synapse development reveals neoteny during human postsynaptic density maturation (2022) (1)
- XSAnno: a framework for building ortholog models in cross-species transcriptome comparisons (2014) (1)
- Molecular programs of regional specification and neural stem cell fate progression in developing macaque telencephalon (2022) (1)
- NogoA-expressing astrocytes limit peripheral macrophage infiltration after ischemic brain injury in primates (2021) (1)
- A screen of brain organoids to study neurodevelopmental disease (2020) (1)
- Expansion of RNA sequence diversity and RNA editing rates throughout human cortical development (2021) (1)
- A multiregional proteomic survey of the postnatal human brain (2017) (1)
- The Molecular Landscape of the Developing Human Central Nervous System (2016) (1)
- Correction: Disruption of NEUROD2 causes a neurodevelopmental syndrome with autistic features via cell-autonomous defects in forebrain glutamatergic neurons (2021) (1)
- 29 BRAINVAR DATA SET: WHOLE-GENOME AND RNA SEQUENCING REVEAL VARIATION AND TRANSCRIPTOMIC COORDINATION IN THE DEVELOPING HUMAN PREFRONTAL CORTEX (2019) (1)
- TRIM71 Mutations Cause Human and Murine Congenital Hydrocephalus by Impairing Prenatal Neural Stem Cell Regulation (2020) (0)
- The ethics of experimenting with human brain tissue (2018) (0)
- Decision letter: Cortical RORβ is required for layer 4 transcriptional identity and barrel integrity (2019) (0)
- Population-averaged macaque brain atlas with high-resolution ex vivo DTI integrated into in vivo space (2017) (0)
- Single Cell Genomic Analysis Reveals Cell Type-Specific Molecular Signatures in the Human PTSD Prefrontal Cortex (2023) (0)
- INSIGHTS INTO THE CONTRIBUTION OF RARE NONCODING VARIATION IN AUTISM SPECTRUM DISORDER THROUGH FAMILY-BASED WHOLE-GENOME SEQUENCING (2019) (0)
- Developmental dynamics of voltage-gated sodium channel isoform expression in the human and mouse brain (2021) (0)
- Cross-ancestry, cell-type-informed atlas of gene, isoform, and splicing regulation in the developing human brain (2023) (0)
- AC-PCA adjusts for confounding variation in transcriptome data and recovers the anatomical structure of neocortex (2016) (0)
- Author response: In silico analysis of the transcriptional regulatory logic of neuronal identity specification throughout the C. elegans nervous system (2021) (0)
- Author Correction: The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing (2021) (0)
- Human-specific features and developmental dynamics of the brain N-glycome (2023) (0)
- 78 Healthcare workers and bloodborne pathogen exposure incidents (2018) (0)
- The Role of In Utero Disruption of Prefrontal Corticothalamic Circuitry in the Etiology of Schizophrenia (2021) (0)
- Experimentsin Hippocampal Neurons: Theory and Geometry of Dendritic Spines Affects Calcium (2015) (0)
- Expression bias in retinoic acid responsive genes defines variations in neural differentiation of human pluripotent stem cells (2022) (0)
- Link to record in KAR (2013) (0)
- 25.2 REGULATION OF PREFRONTAL CORTEX CONNECTIVITY AND PATTERNING BY RETINOIC ACID (2020) (0)
- An analytical framework for whole-genome sequence association studies and its implications for autism spectrum disorder (2018) (0)
- in Rat Medullary Neurons In Situ GABA- and Glycine-Mediated Fall of Intracellular pH (2015) (0)
- Integrative Genomics Implicates Genetic Disruption of Prenatal Neurogenesis in Congenital Hydrocephalus (2020) (0)
- Comparative transcriptome and gene regulation in human iPSC-derived organoids and donor-identical brain tissue (2017) (0)
- AgRP neurons control structure and function of the medial prefrontal cortex (2022) (0)
- A novel SMARCC1-mutant BAFopathy implicates epigenetic dysregulation of neural progenitors in hydrocephalus (2023) (0)
- Building the Human Brain: Molecular Logic of Neural Circuit Development and Evolution (2021) (0)
- Rat Awake Somatic Sensory (SI) Barrel Field Cortex of the Direct Inhibition Evoked by Whisker Stimulation in (2015) (0)
- AC-PCA: simultaneous dimension reduction and adjustment for confounding variation (2016) (0)
- Human cortical neural stem cells generate regional organizer states in vitro before committing to excitatory neuronal fates (2019) (0)
- Modeling Species Specific Gene Expression Across Multiple Regions in the Brain (2020) (0)
- Erratum for Lun et al., Spatially Heterogeneous Choroid Plexus Transcriptomes Encode Positional Identity and Contribute to Regional CSF Production (2015) (0)
- Multi-hit autism genomic architecture evidenced from consanguineous families with involvement of FEZF2 and mutations in high-risk genes (2019) (0)
- Decision letter: Mapping the transcriptional diversity of genetically and anatomically defined cell populations in the mouse brain (2018) (0)
- Notch signaling regulates postnatal neurogenesis in vivo (2007) (0)
- Human neuroepithelial stem cell regional specificity enables spinal cord repair through a relay circuit (2018) (0)
- Restoration of brain circulation and cellular functions hours post-mortem (2019) (0)
- Molecular and cellular mechanisms of human cortical connectivity (2023) (0)
- Mapping origins of variation in neural trajectories of human pluripotent stem cells (2021) (0)
- Histological Relationship with High-Resolution Diffusion Kurtosis Imaging in the Cerebral Cortex (2013) (0)
- A screen of brain organoids to study neurodevelopmental disease (2020) (0)
- Notch signaling regulates the generation of neurons from glial stem cells in the postnatal SEZ (2009) (0)
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