Nevan Krogan
#61,304
Most Influential Person Now
Canadian molecular biologist
Nevan Krogan's AcademicInfluence.com Rankings
Nevan Kroganbiology Degrees
Biology
#2762
World Rank
#4340
Historical Rank
Computational Biology
#116
World Rank
#116
Historical Rank
Molecular Biology
#353
World Rank
#360
Historical Rank
Download Badge
Biology
Why Is Nevan Krogan Influential?
(Suggest an Edit or Addition)According to Wikipedia, Nevan J. Krogan is a Canadian molecular and systems biologist. He is a professor and the Director of the Quantitative Biosciences Institute at the University of California San Francisco , as well as a senior investigator at the J. David Gladstone Institutes.
Nevan Krogan's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A SARS-CoV-2 Protein Interaction Map Reveals Targets for Drug-Repurposing (2020) (3012)
- Global landscape of protein complexes in the yeast Saccharomyces cerevisiae (2006) (2968)
- Global Mapping of the Yeast Genetic Interaction Network (2004) (2113)
- Signals and systems (2006) (1544)
- A Bayesian Networks Approach for Predicting Protein-Protein Interactions from Genomic Data (2003) (1355)
- Interaction network containing conserved and essential protein complexes in Escherichia coli (2005) (1146)
- Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map (2007) (908)
- Exploration of the Function and Organization of the Yeast Early Secretory Pathway through an Epistatic Miniarray Profile (2005) (889)
- Cotranscriptional Set2 Methylation of Histone H3 Lysine 36 Recruits a Repressive Rpd3 Complex (2005) (821)
- Navigating the Chaperone Network: An Integrative Map of Physical and Genetic Interactions Mediated by the Hsp90 Chaperone (2005) (801)
- Toward a Comprehensive Atlas of the Physical Interactome of Saccharomyces cerevisiae*S (2007) (799)
- Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding. (2015) (773)
- The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation. (2003) (762)
- Differential network biology (2012) (716)
- Methylation of Histone H3 by Set2 in Saccharomyces cerevisiae Is Linked to Transcriptional Elongation by RNA Polymerase II (2003) (707)
- The Global Phosphorylation Landscape of SARS-CoV-2 Infection (2020) (651)
- Global landscape of HIV–human protein complexes (2011) (645)
- A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1. (2003) (627)
- Exploration of Essential Gene Functions via Titratable Promoter Alleles (2004) (619)
- Phenotypic Landscape of a Bacterial Cell (2011) (616)
- COMPASS: A complex of proteins associated with a trithorax-related SET domain protein (2001) (594)
- RNA Polymerase II Elongation Factors of Saccharomyces cerevisiae: a Targeted Proteomics Approach (2002) (537)
- The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II (2004) (527)
- INO80 and γ-H2AX Interaction Links ATP-Dependent Chromatin Remodeling to DNA Damage Repair (2004) (526)
- Bre1, an E3 ubiquitin ligase required for recruitment and substrate selection of Rad6 at a promoter. (2003) (524)
- Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation (2013) (523)
- A comprehensive strategy enabling high-resolution functional analysis of the yeast genome (2008) (515)
- A phosphatase complex that dephosphorylates γH2AX regulates DNA damage checkpoint recovery (2006) (481)
- HIV Nef is Secreted in Exosomes and Triggers Apoptosis in Bystander CD4+ T Cells (2010) (481)
- Host Cell Factors in HIV Replication: Meta-Analysis of Genome-Wide Studies (2009) (462)
- Rewiring of Genetic Networks in Response to DNA Damage (2010) (458)
- A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing (2020) (456)
- IFI16 DNA Sensor Is Required for Death of Lymphoid CD4 T Cells Abortively Infected with HIV (2014) (451)
- Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms (2020) (444)
- How many human proteoforms are there? (2018) (440)
- COMPASS, a Histone H3 (Lysine 4) Methyltransferase Required for Telomeric Silencing of Gene Expression* (2002) (426)
- SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signaling receptors (2011) (416)
- Functional Targeting of DNA Damage to a Nuclear Pore-Associated SUMO-Dependent Ubiquitin Ligase (2008) (403)
- High-definition macromolecular composition of yeast RNA-processing complexes. (2004) (392)
- CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs. (2016) (377)
- Inhibition of CRISPR-Cas9 with Bacteriophage Proteins (2017) (367)
- Systematic Functional Prioritization of Protein Posttranslational Modifications (2012) (364)
- Critical Role of Acetylation in Tau-Mediated Neurodegeneration and Cognitive Deficits (2014) (357)
- Conservation and Rewiring of Functional Modules Revealed by an Epistasis Map in Fission Yeast (2008) (356)
- INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair. (2004) (355)
- A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers (2010) (350)
- Histone H2B Ubiquitylation Is Associated with Elongating RNA Polymerase II (2005) (346)
- HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription. (2010) (346)
- The functional landscape of mouse gene expression (2004) (341)
- SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling (2020) (328)
- Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection (2011) (327)
- A strategy for extracting and analyzing large-scale quantitative epistatic interaction data (2006) (327)
- Transitions in RNA polymerase II elongation complexes at the 3′ ends of genes (2004) (315)
- Regulation of chromosome stability by the histone H2A variant Htz1, the Swr1 chromatin remodeling complex, and the histone acetyltransferase NuA4. (2004) (292)
- Functional Organization of the S. cerevisiae Phosphorylation Network (2009) (271)
- Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions (2017) (270)
- A Panoramic View of Yeast Noncoding RNA Processing (2003) (269)
- Test performance evaluation of SARS-CoV-2 serological assays (2020) (266)
- A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing. (2008) (266)
- Evolution and functional cross‐talk of protein post‐translational modifications (2013) (265)
- An Approach to Spatiotemporally Resolve Protein Interaction Networks in Living Cells (2017) (263)
- A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors (2016) (260)
- The Saccharomyces cerevisiae histone H2A variant Htz1 is acetylated by NuA4. (2006) (257)
- An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike (2020) (249)
- Genetic Screens Identify Host Factors for SARS-CoV-2 and Common Cold Coronaviruses (2020) (237)
- H2B ubiquitylation acts as a barrier to Ctk1 nucleosomal recruitment prior to removal by Ubp8 within a SAGA-related complex. (2007) (234)
- An atlas of chaperone–protein interactions in Saccharomyces cerevisiae: implications to protein folding pathways in the cell (2009) (231)
- Proteasome involvement in the repair of DNA double-strand breaks. (2004) (226)
- Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models (2012) (207)
- Learning a Prior on Regulatory Potential from eQTL Data (2009) (206)
- Comparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis (2018) (205)
- Evolution of Phosphoregulation: Comparison of Phosphorylation Patterns across Yeast Species (2009) (204)
- Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response (2015) (202)
- Maintenance of low histone ubiquitylation by Ubp10 correlates with telomere-proximal Sir2 association and gene silencing. (2005) (198)
- Hierarchical modularity and the evolution of genetic interactomes across species. (2012) (198)
- Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A (2021) (197)
- Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation. (2010) (196)
- GammaH2AX and its role in DNA double-strand break repair. (2006) (194)
- A tool-kit for high-throughput, quantitative analyses of genetic interactions in E. coli (2008) (192)
- Chaperone Control of the Activity and Specificity of the Histone H3 Acetyltransferase Rtt109 (2008) (191)
- A gene ontology inferred from molecular networks (2012) (184)
- BUR Kinase Selectively Regulates H3 K4 Trimethylation and H2B Ubiquitylation through Recruitment of the PAF Elongation Complex (2005) (184)
- A Genome-Wide Screen Identifies the Evolutionarily Conserved KEOPS Complex as a Telomere Regulator (2006) (184)
- PIPE: a protein-protein interaction prediction engine based on the re-occurring short polypeptide sequences between known interacting protein pairs (2006) (181)
- Characterization of a Six-Subunit Holo-Elongator Complex Required for the Regulated Expression of a Group of Genes in Saccharomyces cerevisiae (2001) (174)
- Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast (2007) (166)
- Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes. (2015) (157)
- Global Mapping of the Inc-Human Interactome Reveals that Retromer Restricts Chlamydia Infection. (2015) (156)
- Functional Maps of Protein Complexes from Quantitative Genetic Interaction Data (2008) (153)
- High-throughput genetic interaction mapping in the fission yeast Schizosaccharomyces pombe (2007) (151)
- Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action (2010) (149)
- The mTOR Complex Controls HIV Latency. (2016) (148)
- Backup without redundancy: genetic interactions reveal the cost of duplicate gene loss (2007) (146)
- NF-κB-activating complex engaged in response to EGFR oncogene inhibition drives tumor cell survival and residual disease in lung cancer. (2015) (146)
- H2B Ubiquitin Protease Ubp8 and Sgf11 Constitute a Discrete Functional Module within the Saccharomyces cerevisiae SAGA Complex (2005) (145)
- Evolution of enhanced innate immune evasion by SARS-CoV-2 (2021) (144)
- Quantitative Genetic Interactions Reveal Biological Modularity (2010) (142)
- The ctf13-30/CTF13 Genomic Haploinsufficiency Modifier Screen Identifies the Yeast Chromatin Remodeling Complex RSC, Which Is Required for the Establishment of Sister Chromatid Cohesion (2004) (139)
- Mec1/Tel1 Phosphorylation of the INO80 Chromatin Remodeling Complex Influences DNA Damage Checkpoint Responses (2007) (134)
- A Cas9 Ribonucleoprotein Platform for Functional Genetic Studies of HIV-Host Interactions in Primary Human T Cells. (2016) (133)
- Genetic interaction mapping in mammalian cells using CRISPR interference (2017) (132)
- Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment (2008) (132)
- Functional Overlap and Regulatory Links Shape Genetic Interactions between Signaling Pathways (2010) (131)
- The Dengue Virus NS5 Protein Intrudes in the Cellular Spliceosome and Modulates Splicing (2016) (130)
- From Structure to Systems: High-Resolution, Quantitative Genetic Analysis of RNA Polymerase II (2013) (126)
- Evaluation of SARS-CoV-2 serology assays reveals a range of test performance (2020) (125)
- A lipid E-MAP identifies Ubx2 as a critical regulator of lipid saturation and lipid bilayer stress. (2013) (124)
- Cotranscriptional Set 2 Methylation of Histone H 3 Lysine 36 Recruits a Repressive Rpd 3 Complex (2005) (124)
- The Shwachman-Bodian-Diamond Syndrome Protein Family Is Involved in RNA Metabolism* (2005) (119)
- A combined proteomics/genomics approach links hepatitis C virus infection with nonsense-mediated mRNA decay. (2015) (116)
- First-in-class small molecule inhibitors of the single-strand DNA cytosine deaminase APOBEC3G. (2012) (113)
- Host Cell Interactome of HIV-1 Rev Includes RNA Helicases Involved in Multiple Facets of Virus Production* (2011) (113)
- Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication (2015) (112)
- Quantitative genetic-interaction mapping in mammalian cells (2013) (112)
- A single SR-like protein, Npl3, promotes pre-mRNA splicing in budding yeast. (2008) (111)
- Polycomb-Like 3 Promotes Polycomb Repressive Complex 2 Binding to CpG Islands and Embryonic Stem Cell Self-Renewal (2012) (111)
- Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2 (2021) (109)
- Histone H 2 B Ubiquitylation Is Associated with Elongating RNA Polymerase II (2004) (107)
- Eisosome proteins assemble into a membrane scaffold (2011) (106)
- The cancer cell map initiative: defining the hallmark networks of cancer. (2015) (105)
- A plasma-membrane E-MAP reveals links of the eisosome with sphingolipid metabolism and endosomal trafficking (2010) (105)
- CBFβ stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression. (2013) (103)
- Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection. (2016) (103)
- CCR4/NOT complex associates with the proteasome and regulates histone methylation (2007) (101)
- The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders (2018) (101)
- Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome (2021) (100)
- Microcephaly Proteins Wdr62 and Aspm Define a Mother Centriole Complex Regulating Centriole Biogenesis, Apical Complex, and Cell Fate (2016) (100)
- Ensemble non-negative matrix factorization methods for clustering protein-protein interactions (2008) (96)
- The H3K36me2 Methyltransferase Nsd1 Demarcates PRC2-Mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells. (2018) (95)
- A Complex-based Reconstruction of the Saccharomyces cerevisiae Interactome *S⃞ (2009) (94)
- Quantitative genetic analysis in Saccharomyces cerevisiae using epistatic miniarray profiles (E-MAPs) and its application to chromatin functions. (2006) (94)
- Quantitative genetic interaction mapping using the E-MAP approach. (2010) (92)
- Protein Interaction Mapping Identifies RBBP6 as a Negative Regulator of Ebola Virus Replication (2018) (92)
- Dissection of DNA damage responses using multiconditional genetic interaction maps. (2013) (92)
- Evolution of enhanced innate immune evasion by the SARS-CoV-2 B.1.1.7 UK variant (2021) (91)
- An acetylated form of histone H2A.Z regulates chromosome architecture in Schizosaccharomyces pombe (2009) (85)
- High-resolution network biology: connecting sequence with function (2013) (84)
- SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy (2018) (82)
- Test performance evaluation of SARS-CoV-2 serological assays (2020) (80)
- HIV-1 Tat recruits transcription elongation factors dispersed along a flexible AFF4 scaffold (2012) (80)
- Metabolic reprogramming of human CD8+ memory T cells through loss of SIRT1 (2018) (79)
- CRISPR–Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV–host factor interactions (2018) (76)
- Anti-CRISPR-Associated Proteins Are Crucial Repressors of Anti-CRISPR Transcription (2019) (75)
- A Snf 2 Family ATPase Complex Required for Recruitment of the Histone H 2 A Variant Htz (2003) (74)
- Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. (2011) (74)
- A BAG3 chaperone complex maintains cardiomyocyte function during proteotoxic stress. (2017) (73)
- Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission (2022) (73)
- Large dataset enables prediction of repair after CRISPR–Cas9 editing in primary T cells (2019) (72)
- Evolutionary Proteomics Uncovers Ancient Associations of Cilia with Signaling Pathways. (2017) (72)
- The RNA Polymerase II Kinase Ctk1 Regulates Positioning of a 5′ Histone Methylation Boundary along Genes (2006) (71)
- AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation (2013) (70)
- An Mtb-Human Protein-Protein Interaction Map Identifies a Switch between Host Antiviral and Antibacterial Responses. (2018) (70)
- SMYD2-Mediated Histone Methylation Contributes to HIV-1 Latency. (2017) (69)
- Translation of Genotype to Phenotype by a Hierarchy of Cell Subsystems (2016) (68)
- Genome-Wide Association Data Reveal a Global Map of Genetic Interactions among Protein Complexes (2009) (68)
- The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat (2013) (67)
- Identification and Characterization of Elf1, a Conserved Transcription Elongation Factor in Saccharomyces cerevisiae (2005) (67)
- Cullin E3 Ligases and Their Rewiring by Viral Factors (2014) (65)
- GPS-Prot: A web-based visualization platform for integrating host-pathogen interaction data (2011) (64)
- Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3G (2012) (62)
- Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2 (2020) (62)
- Epistatic relationships reveal the functional organization of yeast transcription factors (2010) (61)
- Acetylome Profiling Reveals Overlap in the Regulation of Diverse Processes by Sirtuins, Gcn5, and Esa1* (2014) (61)
- Purification and characterization of HIV–human protein complexes (2010) (61)
- A scaffold protein connects type IV pili with the Chp chemosensory system to mediate activation of virulence signaling in Pseudomonas aeruginosa (2016) (60)
- Multiple Routes to Oncogenesis Are Promoted by the Human Papillomavirus-Host Protein Network. (2018) (60)
- The Cellular NMD Pathway Restricts Zika Virus Infection and Is Targeted by the Viral Capsid Protein (2018) (59)
- A systems approach to infectious disease (2020) (59)
- A Chaperone-Assisted Degradation Pathway Targets Kinetochore Proteins to Ensure Genome Stability (2014) (58)
- Unc93b1 recruits Syntenin-1 to dampen TLR7 signaling and prevent autoimmunity (2018) (58)
- Mutations in ANKLE2, a ZIKA Virus Target, Disrupt an Asymmetric Cell Division Pathway in Drosophila Neuroblasts to Cause Microcephaly. (2019) (58)
- RNA Polymerase II Carboxyl-terminal Domain Phosphorylation Regulates Protein Stability of the Set2 Methyltransferase and Histone H3 Di- and Trimethylation at Lysine 36* (2011) (57)
- Mutations in the X-linked ATP6AP2 cause a glycosylation disorder with autophagic defects (2017) (56)
- Linking tumor mutations to drug responses via a quantitative chemical-genetic interaction map. (2015) (55)
- The Yeast SR-Like Protein Npl3 Links Chromatin Modification to mRNA Processing (2012) (55)
- The Host E3-Ubiquitin Ligase TRIM6 Ubiquitinates the Ebola Virus VP35 Protein and Promotes Virus Replication (2017) (54)
- Chlamydia interfere with an interaction between the mannose-6-phosphate receptor and sorting nexins to counteract host restriction (2017) (54)
- Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration (2022) (53)
- Correction: Evolution of Phosphoregulation: Comparison of Phosphorylation Patterns across Yeast Species (2009) (53)
- SARS-CoV-2 ORF9c Is a Membrane-Associated Protein that Suppresses Antiviral Responses in Cells (2020) (52)
- Interaction of Fcp1 Phosphatase with Elongating RNA Polymerase II Holoenzyme, Enzymatic Mechanism of Action, and Genetic Interaction with Elongator* (2005) (52)
- Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the viral Core (2019) (51)
- Systems-level analyses identify extensive coupling among gene expression machines (2006) (50)
- Scoring Large‐Scale Affinity Purification Mass Spectrometry Datasets with MiST (2015) (50)
- The AMBRA1 E3 ligase adaptor regulates the stability of cyclin D (2021) (49)
- Association with the origin recognition complex suggests a novel role for histone acetyltransferase Hat1p/Hat2p (2007) (49)
- Differential genetic interactions of yeast stress response MAPK pathways (2015) (48)
- Cyclin-Dependent Kinase 12 Increases 3′ End Processing of Growth Factor-Induced c-FOS Transcripts (2014) (48)
- The Prefoldin Complex Regulates Chromatin Dynamics during Transcription Elongation (2013) (47)
- Regulation of Sufu activity by p66β and Mycbp provides new insight into vertebrate Hedgehog signaling (2014) (46)
- Lineage-Specific Viral Hijacking of Non-canonical E3 Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC3 Activity. (2015) (45)
- Identification of Antiviral Roles for the Exon-Junction Complex and Nonsense-Mediated Decay in Flaviviral Infection (2019) (45)
- CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes. (2021) (45)
- Mass spectrometry‐based protein–protein interaction networks for the study of human diseases (2021) (44)
- A SARS-CoV-2 protein interaction map reveals targets for drug repurposing (2020) (43)
- The RNA Exosome Syncs IAV-RNAPII Transcription to Promote Viral Ribogenesis and Infectivity (2017) (43)
- CDK11 in TREX/THOC Regulates HIV mRNA 3' End Processing. (2015) (42)
- Systematic Identification of Host Cell Regulators of Legionella pneumophila Pathogenesis Using a Genome-wide CRISPR Screen. (2019) (41)
- Unbiased Proteomic Profiling Uncovers a Targetable GNAS/PKA/PP2A Axis in Small Cell Lung Cancer Stem Cells. (2020) (41)
- Suppression of C9orf72 RNA repeat-induced neurotoxicity by the ALS-associated RNA-binding protein Zfp106 (2016) (40)
- The Landscape of Human Cancer Proteins Targeted by SARS-CoV-2 (2020) (40)
- Systematic triple-mutant analysis uncovers functional connectivity between pathways involved in chromosome regulation. (2013) (40)
- Neuronal Apolipoprotein E4 Expression Results in Proteome-Wide Alterations and Compromises Bioenergetic Capacity by Disrupting Mitochondrial Function (2019) (40)
- Thioredoxin-related Protein 32 Is an Arsenite-regulated Thiol Reductase of the Proteasome 19 S Particle* (2009) (39)
- Envelope protein ubiquitination drives entry and pathogenesis of Zika virus (2020) (38)
- Bromodomain Factor 1 (Bdf1) Is Phosphorylated by Protein Kinase CK2 (2004) (37)
- Enterovirus Pathogenesis Requires the Host Methyltransferase SETD3 (2019) (37)
- Key Functional Regions in the Histone Variant H2A.Z C-Terminal Docking Domain (2011) (37)
- Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities (2022) (37)
- From systems to structure: bridging networks and mechanism. (2013) (37)
- Replication Fork Collapse and Genome Instability in a Deoxycytidylate Deaminase Mutant (2012) (37)
- Systematic characterization of the protein interaction network and protein complexes in Saccharomyces cerevisiae using tandem affinity purification and mass spectrometry. (2009) (36)
- Esf2p, a U3-Associated Factor Required for Small-Subunit Processome Assembly and Compaction (2005) (36)
- A systematic characterization of Cwc21, the yeast ortholog of the human spliceosomal protein SRm300. (2009) (35)
- Influenza virus infection causes global RNAPII termination defects (2018) (35)
- Individual Lysine Acetylations on the N Terminus of Saccharomyces cerevisiae H2A.Z Are Highly but Not Differentially Regulated* (2010) (34)
- All or Nothing: Protein Complexes Flip Essentiality between Distantly Related Eukaryotes (2013) (34)
- Discovery and functional characterization of a neomorphic PTEN mutation (2015) (34)
- Structural Basis of CD4 Downregulation by HIV-1 Nef (2020) (34)
- The Tyrosine Kinase Inhibitor Gefitinib Restricts Mycobacterium tuberculosis Growth through Increased Lysosomal Biogenesis and Modulation of Cytokine Signaling. (2017) (33)
- A Herpesvirus Protein Selectively Inhibits Cellular mRNA Nuclear Export. (2016) (33)
- An Rtt109-Independent Role for Vps75 in Transcription-Associated Nucleosome Dynamics (2009) (32)
- A Pil1–Sle1–Syj1–Tax4 functional pathway links eisosomes with PI(4,5)P2 regulation (2014) (32)
- Chemical genetics of rapamycin-insensitive TORC2 in S. cerevisiae. (2013) (32)
- Adventures in time and space (2014) (32)
- Non-degradative Ubiquitination of Protein Kinases (2016) (32)
- Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer. (2018) (31)
- Comparative mapping of host-pathogen protein-protein interactions. (2015) (31)
- Proteome Imbalance of Mitochondrial Electron Transport Chain in Brown Adipocytes Leads to Metabolic Benefits. (2018) (31)
- Moloney Leukemia Virus Type 10 Inhibits Reverse Transcription and Retrotransposition of Intracisternal A Particles (2012) (30)
- ARIH2 Is a Vif-Dependent Regulator of CUL5-Mediated APOBEC3G Degradation in HIV Infection. (2019) (30)
- Set5 and Set1 cooperate to repress gene expression at telomeres and retrotransposons (2014) (30)
- Adhesion-mediated mechanosignaling forces mitohormesis (2020) (30)
- A Chemical-Genomic Screen of Neglected Antibiotics Reveals Illicit Transport of Kasugamycin and Blasticidin S (2016) (30)
- Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunits (2020) (29)
- EpCAM homo-oligomerization is not the basis for its role in cell-cell adhesion (2018) (29)
- An ultra-high affinity synthetic nanobody blocks SARS-CoV-2 infection by locking Spike 1 into an inactive conformation 2 (2020) (29)
- Combined Action of Histone Reader Modules Regulates NuA4 Local Acetyltransferase Function but Not Its Recruitment on the Genome (2016) (29)
- Conflicting and ambiguous names of overlapping ORFs in the SARS-CoV-2 genome: A homology-based resolution (2021) (29)
- An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation (2020) (29)
- SUMO is a pervasive regulator of meiosis (2021) (29)
- A protein interaction landscape of breast cancer (2021) (28)
- Genetic Interaction Mapping Reveals a Role for the SWI/SNF Nucleosome Remodeler in Spliceosome Activation in Fission Yeast (2015) (27)
- Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B.1.1.7 variant (2021) (26)
- Site-specific acetylation mark on an essential chromatin-remodeling complex promotes resistance to replication stress (2011) (26)
- Dynamic post-translational modification profiling of Mycobacterium tuberculosis-infected primary macrophages (2020) (26)
- SIRT3 controls brown fat thermogenesis by deacetylation regulation of pathways upstream of UCP1 (2019) (26)
- Chaperone-mediated reflux of secretory proteins to the cytosol during endoplasmic reticulum stress (2019) (25)
- Functional genomic screens identify human host factors for SARS-CoV-2 and common cold coronaviruses (2020) (25)
- The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation (2018) (24)
- Proteasome lid bridges mitochondrial stress with Cdc53/Cullin1 NEDDylation status (2018) (24)
- Dynamic BAF chromatin remodeling complex subunit inclusion promotes temporally distinct gene expression programs in cardiogenesis (2019) (24)
- G Protein–Coupled Receptor Endocytosis Confers Uniformity in Responses to Chemically Distinct Ligands (2017) (24)
- Proteomic Approaches to Study SARS-CoV-2 Biology and COVID-19 Pathology (2021) (23)
- PJA2 ubiquitinates the HIV-1 Tat protein with atypical chain linkages to activate viral transcription (2017) (23)
- Systems-based Analysis of RIG-I-dependent Signaling Identifies KHSRP as an Inhibitor of RIG-I Receptor Activation (2017) (23)
- Sympathetic inputs regulate adaptive thermogenesis in brown adipose tissue through cAMP-Salt inducible kinase axis (2018) (23)
- Towards accurate imputation of quantitative genetic interactions (2009) (23)
- Two Accessory Proteins Govern MmpL3 Mycolic Acid Transport in Mycobacteria (2019) (22)
- A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity (2021) (22)
- Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection (2020) (21)
- The histone variant H2A.Z promotes splicing of weak introns (2017) (21)
- Corrigendum: A phosphatase complex that dephosphorylates γH2AX regulates DNA damage checkpoint recovery (2006) (21)
- High-Throughput Genetic and Gene Expression Analysis of the RNAPII-CTD Reveals Unexpected Connections to SRB10/CDK8 (2013) (20)
- A ciliopathy complex builds distal appendages to initiate ciliogenesis (2021) (20)
- Investigating the in vivo activity of the DeaD protein using protein–protein interactions and the translational activity of structured chloramphenicol acetyltransferase mRNAs (2007) (20)
- Preclinical and randomized phase I studies of plitidepsin in adults hospitalized with COVID-19 (2022) (19)
- Spindle Checkpoint Factors Bub1 and Bub2 Promote DNA Double-Strand Break Repair by Nonhomologous End Joining (2015) (19)
- Heart failure drug proscillaridin A targets MYC overexpressing leukemia through global loss of lysine acetylation (2019) (19)
- Dispersed sites of HIV Vif-dependent polyubiquitination in the DNA deaminase APOBEC3F. (2013) (19)
- Protein Moonlighting Revealed by Noncatalytic Phenotypes of Yeast Enzymes (2017) (19)
- Envelope Protein Ubiquitination Drives Zika Virus Entry and Pathogenesis (2020) (18)
- Efficient generation of isogenic primary human myeloid cells using CRISPR-Cas9 ribonucleoproteins (2020) (18)
- Fab-based inhibitors reveal ubiquitin independent functions for HIV Vif neutralization of APOBEC3 restriction factors (2018) (17)
- ESF1 is required for 18S rRNA synthesis in Saccharomyces cerevisiae. (2004) (17)
- Quantitative analysis of triple-mutant genetic interactions (2014) (17)
- The next frontier of systems biology: higher-order and interspecies interactions (2010) (17)
- The Yeast DNA Damage Checkpoint Kinase Rad53 Targets the Exoribonuclease, Xrn1 (2018) (16)
- PEAK3/C19orf35 pseudokinase, a new NFK3 kinase family member, inhibits CrkII through dimerization (2019) (16)
- Crosstalk between RNA Pol II C-Terminal Domain Acetylation and Phosphorylation via RPRD Proteins. (2019) (15)
- Virus-Like Vesicles of Kaposi's Sarcoma-Associated Herpesvirus Activate Lytic Replication by Triggering Differentiation Signaling (2017) (15)
- From information to knowledge: new technologies for defining gene function (2009) (15)
- Mycobacterial Mutagenesis and Drug Resistance Are Controlled by Phosphorylation- and Cardiolipin-Mediated Inhibition of the RecA Coprotease. (2018) (15)
- Restriction factor compendium for influenza A virus reveals a mechanism for evasion of autophagy (2021) (15)
- SARS-CoV-2 variants of concern have acquired mutations associated with an increased spike cleavage (2021) (15)
- Bringing it all together: big data and HIV research. (2013) (15)
- Mapping genetic interactions in cancer: a road to rational combination therapies (2019) (15)
- Genetic interaction mapping informs integrative structure determination of protein complexes (2020) (15)
- Nonsense-mediated decay regulates key components of homologous recombination (2016) (15)
- A functional map of HIV-host interactions in primary human T cells (2022) (14)
- Endosomal cAMP production broadly impacts the cellular phosphoproteome (2021) (14)
- Determinants for degradation of SAMHD1, Mus81 and induction of G2 arrest in HIV-1 Vpr and SIVagm Vpr. (2015) (14)
- Systems Analyses Reveal Shared and Diverse Attributes of Oct4 Regulation in Pluripotent Cells. (2015) (14)
- Mapping the protein-protein and genetic interactions of cancer to guide precision medicine. (2019) (14)
- Quantitative Yeast Genetic Interaction Profiling of Bacterial Effector Proteins Uncovers a Role for the Human Retromer in Salmonella Infection. (2018) (13)
- A Quantitative Genetic Interaction Map of HIV Infection. (2020) (13)
- Yeast X‐chromosome‐associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts (2014) (13)
- Comparative interaction networks: bridging genotype to phenotype. (2012) (12)
- Optimal stepwise experimental design for pairwise functional interaction studies (2008) (12)
- Conditional Genetic Interactions of RTT107, SLX4, and HRQ1 Reveal Dynamic Networks upon DNA Damage in S. cerevisiae (2014) (12)
- Interpretation of cancer mutations using a multiscale map of protein systems (2021) (12)
- CRL4AMBRA1 targets Elongin C for ubiquitination and degradation to modulate CRL5 signaling (2018) (12)
- SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses (2018) (12)
- Prediction of Functionally Important Phospho-Regulatory Events in Xenopus laevis Oocytes (2015) (11)
- Virus and host interactions critical for filoviral RNA synthesis as therapeutic targets (2019) (11)
- Identification of a BET family bromodomain/casein kinase II/TAF-containing complex as a regulator of mitotic condensin function. (2014) (11)
- Evolutionarily conserved genetic interactions with budding and fission yeast MutS identify orthologous relationships in mismatch repair-deficient cancer cells (2014) (11)
- Genetic analysis reveals functions of atypical polyubiquitin chains (2018) (10)
- Evaluating a New Class of AKT/mTOR Activators for HIV Latency-Reversing Activity Ex Vivo and In Vivo (2021) (10)
- Genetic Interaction Landscape Reveals Critical Requirements for Schizosaccharomyces pombe Brc1 in DNA Damage Response Mutants (2015) (10)
- Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD (2022) (10)
- From systems to structure — using genetic data to model protein structures (2022) (9)
- Viral E Protein Neutralizes BET Protein-Mediated Post-Entry Antagonism of SARS-CoV-2 (2021) (9)
- Transcription factor protein interactomes reveal genetic determinants in heart disease (2022) (9)
- Functional genomics of the yeast DNA-damage response (2006) (9)
- Crosstalk between RNA Pol II C-Terminal Domain Acetylation and Phosphorylation via RPRD Proteins (2018) (9)
- Brahma safeguards canalization of cardiac mesoderm differentiation (2022) (8)
- Plitidepsin has a positive therapeutic index in adult patients with COVID-19 requiring hospitalization. (2021) (8)
- Phospholipidosis is a shared mechanism underlying the in vitro antiviral activity of many repurposed drugs against SARS-CoV-2 (2021) (8)
- Conflicting and Ambiguous Names of Overlapping ORFs in SARS-CoV-2: A Homology-Based Resolution (2020) (8)
- Synthetic essentiality of metabolic regulator PDHK1 in PTEN-deficient cells and cancers (2018) (8)
- Genetic interaction analysis of point mutations enables interrogation of gene function at a residue‐level resolution (2014) (8)
- Therapeutic implications of activating noncanonical PIK3CA mutations in head and neck squamous cell carcinoma. (2021) (8)
- SIN-fully silent: HDAC complexes in fission yeast (2007) (7)
- Global post-translational modification profiling of HIV-1-infected cells reveals mechanisms of host cellular pathway remodeling (2020) (7)
- Systems-level effects of allosteric perturbations to a model molecular switch (2021) (7)
- CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes. (2021) (7)
- SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein (2022) (7)
- A Combination of Three Mutations, dcd,pyrH, and cdd, Establishes Thymidine (Deoxyuridine) Auxotrophy in thyA+ Strains of Salmonella typhimurium (1998) (7)
- The RNA helicase DHX16 recognizes specific viral RNA to trigger RIG-I-dependent innate antiviral immunity (2022) (7)
- Regulation of Skn7-dependent, oxidative stress-induced genes by the RNA polymerase II-CTD phosphatase, Fcp1, and Mediator kinase subunit, Cdk8, in yeast (2019) (6)
- Brown adipocyte ATF4 activation improves thermoregulation and systemic metabolism. (2021) (6)
- Caveolin-1 and Sox-2 are predictive biomarkers of cetuximab response in head and neck cancer (2021) (5)
- Systematic characterization of genome editing in primary T cells reveals proximal genomic insertions and enables machine learning prediction of CRISPR-Cas9 DNA repair outcomes (2018) (5)
- BAC to the future: functional genomics in mammals (2008) (5)
- Escherichia coli mRNAs with strong Shine/Dalgarno sequences also contain 5' end sequences complementary to domain # 17 on the 16S ribosomal RNA. (2004) (5)
- IL-10 driven memory T cell survival and Tfh differentiation promote HIV persistence (2021) (5)
- The E3 Ubiquitin-Protein Ligase Cullin 3 Regulates HIV-1 Transcription (2020) (5)
- UNC93B1 recruits syntenin-1 to dampen TLR7 signalling and prevent autoimmunity (2019) (5)
- The kinase Isr1 negatively regulates hexosamine biosynthesis in S. cerevisiae (2020) (4)
- Genetic Interaction Mapping in Schizosaccharomyces pombe Using the Pombe Epistasis Mapper (PEM) System and a ROTOR HDA Colony Replicating Robot in a 1536 Array Format. (2018) (4)
- High-Throughput Quantitative Genetic Interaction Mapping in the Fission Yeast Schizosaccharomyces pombe. (2018) (4)
- Creating collaboration by breaking down scientific barriers (2021) (4)
- Distinct configurations of protein complexes and biochemical pathways revealed by epistatic interaction network motifs (2011) (4)
- Ankle2, A Target of Zika Virus, Controls Asymmetric Cell Division of Neuroblasts and Uncovers a Novel Microcephaly Pathway (2019) (4)
- The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity (2020) (4)
- Improved functional overview of protein complexes using inferred epistatic relationships (2011) (4)
- Non‐canonical proline‐tyrosine interactions with multiple host proteins regulate Ebola virus infection (2021) (4)
- Imputing and predicting quantitative genetic interactions in epistatic MAPs. (2011) (4)
- Prb1 Protease Activity Is Required for Its Recognition by the F-Box Protein Saf1. (2015) (4)
- Target Discovery for Host-Directed Antiviral Therapies: Application of Proteomics Approaches (2021) (4)
- Splicing Defects of the Profilin Gene Alter Actin Dynamics in an S. pombe SMN Mutant (2019) (4)
- Chlamydia trachomatis effector Dre1 interacts with dynactin to reposition host organelles during infection (2022) (4)
- Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis (2022) (3)
- NF-k B-Activating Complex Engaged in Response to EGFR Oncogene Inhibition Drives Tumor Cell Survival and Residual Disease in Lung Cancer Graphical (2015) (3)
- MOV10 inhibits IAP reverse transcription and retrotransposition (2012) (3)
- Large dataset enables prediction of repair after CRISPR–Cas9 editing in primary T cells (2019) (3)
- Chapter 12 The Virus–Host Interactome Knowing the Players to Understand the Game (2016) (3)
- Chemical-genetic interrogation of RNA polymerase mutants reveals structure-function relationships and physiological tradeoffs. (2021) (3)
- Transformation of Schizosaccharomyces pombe in a 96-Well Format. (2018) (3)
- Genetic Interaction Score (S-Score) Calculation, Clustering, and Visualization of Genetic Interaction Profiles for Yeast. (2018) (3)
- SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein (2022) (3)
- DLX1 and the NuRD complex cooperate in enhancer decommissioning and transcriptional repression. (2022) (3)
- Profiling the diversity of agonist-selective effects on the proximal proteome environment of G protein-coupled receptors (2022) (3)
- Reduced endosomal microautophagy activity in aging associates with enhanced exocyst‐mediated protein secretion (2022) (3)
- DNA Preparation from Schizosaccharomyces pombe. (2018) (3)
- Non-canonical proline-tyrosine interactions with multiple host proteins regulate Ebola virus infection (2020) (2)
- Protein-Protein Interactions from Genomic Data A Bayesian Networks Approach for Predicting (2006) (2)
- Dynamic proteomics profiling of Legionella pneumophila infection unveils modulation of the host mitochondrial stress response pathway (2020) (2)
- Zika Virus Infection Prevents Host mRNA Nuclear Export by Disrupting UPF1 Function (2020) (2)
- Targeting MYC Overexpressing Leukemia with Cardiac Glycoside Proscillaridin Through Downregulation of Histone Acetyltransferases (2018) (2)
- Author response: Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response (2015) (2)
- Author response: Chlamydia interfere with an interaction between the mannose-6-phosphate receptor and sorting nexins to counteract host restriction (2017) (2)
- An ancient viral epidemic involving host coronavirus interacting genes more than 20,000 years ago in East Asia (2021) (2)
- GPCR endocytosis confers uniformity in responses to chemically distinct ligands (2016) (2)
- BAF chromatin remodeling complex subunit diversity promotes temporally distinct gene expression programs in cardiogenesis (2017) (2)
- Characterization of an A3G-VifHIV-1-CRL5-CBFβ Structure Using a Cross-linking Mass Spectrometry Pipeline for Integrative Modeling of Host–Pathogen Complexes (2021) (2)
- Cardiac Cell-Derived Matrices Impart Age-Specific Functional Properties to Human Cardiomyocytes (2020) (2)
- Phosphorylation and ubiquitylation crosstalk in protein degradation (2013) (2)
- Delineation of the SUMO-Modified Proteome Reveals Regulatory Functions Throughout Meiosis (2019) (2)
- A CRISPR-Cas9 Genome Engineering Platform in Primary CD4+ T Cells for the Interrogation of HIV Host Factors (2017) (2)
- De novo protein identification in mammalian sperm using high-resolution in situ cryo-electron tomography (2022) (2)
- CCL2: a Chemokine Potentially Promoting Early Seeding of the Latent HIV Reservoir (2022) (2)
- Comparative Analysis of T-Cell Spatial Proteomics and the Influence of HIV Expression (2021) (2)
- Evaluation of SARS-CoV-2 serology assays reveals a range of test performance (2020) (2)
- mRNA display with library of even-distribution reveals cellular interactors of influenza virus NS1 (2020) (2)
- The Virus–Host Interactome (2016) (2)
- An Mtb-Human Protein-Protein Interaction Map Reveals that Bacterial LpqN Antagonizes CBL, a Host Ubiquitin Ligase that Regulates the Balance Between Anti-Viral and Anti-Bacterial Responses (2017) (2)
- A Legionella toxin mimics tRNA and glycosylates the translation machinery to trigger a ribotoxic stress response (2022) (2)
- Author response: Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication (2015) (2)
- Integration of Protein Interactome Networks with Congenital Heart Disease Variants Reveals Candidate Disease Genes (2020) (1)
- Bimodal evolution of Src and Abl kinase substrate specificity revealed using mammalian cell extract as substrate pool (2020) (1)
- Tau interactome mapping reveals dynamic processes in synapses and mitochondria associated with neurodegenerative disease (2021) (1)
- Correction: Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer. (2022) (1)
- SARS-CoV-2 variants of concern have acquired mutations associated with an 1 increased spike cleavage 2 (2021) (1)
- Functional analysis of a common BAG3 allele associated with protection from heart failure (2021) (1)
- Proteomic Organellar Mapping Reveals Modulation of Peroxisomes by HIV-1 (2021) (1)
- Oncogenic PKA signaling increases c-MYC protein expression through multiple targetable mechanisms (2023) (1)
- A whole genome CRISPR screen identifies AHR loss as a mechanism of PARP7 inhibitor resistance. (2022) (1)
- Global landscape of the host response to SARS-CoV-2 variants reveals viral evolutionary trajectories (2022) (1)
- Lineage-Specific Viral Hija cking of Non-canonical E 3 Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC 3 Activity Graphical (2015) (1)
- Oncogenic PKA signaling stabilizes MYC oncoproteins via an aurora kinase A-dependent mechanism (2021) (1)
- Comparative analysis of macrophage post-translational modifications during intracellular bacterial pathogen infection (2020) (1)
- Discovery of UFO Proteins: Human-Virus Chimeric Proteins Generated During Influenza Virus Infection (2019) (1)
- Nuclear accumulation of host transcripts during Zika Virus Infection (2023) (1)
- Erratum: COMPASS: A complex of proteins associated with a trithorax-related SET domain protein (Proceedings of the National Academy of Sciences of the United States of America (November 6, 2001) 98:23 (112902-12907)) (2001) (1)
- Type I IFN promotes pathogenic inflammatory monocyte maturation during H5N1 infection (2022) (1)
- Resource Chemical Genetics of Rapamycin-Insensitive TORC 2 in S . cerevisiae (2013) (1)
- mRNA display with library of even-distribution reveals cellular interactors of influenza virus NS1 (2020) (1)
- Viral E protein neutralizes BET protein-mediated post-entry antagonism of SARS-CoV-2 (2022) (1)
- Leveraging modeling and simulation to optimize the therapeutic window for epigenetic modifier drugs. (2022) (1)
- Resource Systematic Functional Prioritization of Protein Posttranslational Modifications (2012) (1)
- Signaling Snapshots of 5-HT 2BR Activated by the Prototypical Psychedelic LSD (2022) (1)
- A Plasma Membrane EMAP Reveals Links Between the Eisosome , Sphingolipid Metabolism and Endosomal Trafficking (2010) (1)
- Evolutionary proteomics uncovers ciliary signaling components (2017) (1)
- Hepatitis C Virus Infects and Perturbs Liver Stem Cells (2021) (1)
- Data and text mining Ensemble non-negative matrix factorization methods for clustering protein – protein interactions (2008) (0)
- PNAS Plus Significance Statements (2014) (0)
- Abstract 1381: Targeting histone acetyltransferases to reprogram high C-MYC expressing cancers (2018) (0)
- Protein Moonlighting Revealed by Non-Catalytic Phenotypes of Yeast Enzymes (2017) (0)
- Resource An Mtb-Human Protein-Pr otein Interaction Map Identifies a Switch between Host Antiviral and Antibacterial Responses Graphical (2018) (0)
- Abstract 3297: A tyrosine kinase interactome reveals network states that guide the use of targeted therapies in cancer (2018) (0)
- Genetic and Proteomic Dissection of TDP43 Toxicity in S. cerevisiae (2012) (0)
- Title All or Nothing : protein complexes flip essentiality betweendistantly related eukaryotes (2017) (0)
- Abstract IA03: Systems approaches reveal shared pathways affected in SARS-CoV-2 infection and cancer (2020) (0)
- Abstract 934: Physical and Genetic Interaction Analyses in Human Pluripotent Stem Cell-Derived Cardiomyocytes to Study Protein Quality Control Disease in the Heart (2019) (0)
- Structural insights into regulation of the PEAK3 pseudokinase scaffold by 14-3-3 (2022) (0)
- Low expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication (2022) (0)
- TCO, a Putative Transcriptional Regulator in Arabidopsis, Is a Target of the Protein Kinase CK2 (2018) (0)
- Structure-function analysis of enterovirus protease 2A in complex with its essential host factor SETD3 (2022) (0)
- Heart failure drug proscillaridin A targets MYC overexpressing leukemia through global loss of lysine acetylation (2019) (0)
- EpCAM homo-oligomerization is not the basis for its role in cell-cell adhesion (2018) (0)
- Envelope protein ubiquitination drives entry and pathogenesis of Zika virus (2020) (0)
- Abstract B016: Inhibition of KRASG12C in colon cancer illustrates a link between beta-catenin, WNK, and the GID complex (2022) (0)
- Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13 (2023) (0)
- SARS-CoV-2 Spike in complex with neutralizing nanobody mNb6 (2020) (0)
- Next-generation interaction proteomics for quantitative Jumbophage-bacteria interaction mapping (2023) (0)
- Resistance to ATR Inhibitors Is Mediated by Loss of the Nonsense-Mediated Decay Factor UPF2. (2022) (0)
- Quantitative proteomic analysis reveals apoE4-dependent phosphorylation of the actin-regulating protein VASP (2022) (0)
- Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13 (2023) (0)
- Identification of antiviral roles for the exon–junction complex and nonsense-mediated decay in flaviviral infection (2019) (0)
- A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication and pathogenesis in vivo (2023) (0)
- A vision of immuno-oncology: the Siena think tank of the Italian network for tumor biotherapy (NIBIT) foundation (2021) (0)
- CRISPR–Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV–host factor interactions (2018) (0)
- An automated proximity proteomics pipeline for subcellular proteome and protein interaction mapping (2023) (0)
- Workshop-based learning and networking: a scalable model for research capacity strengthening in low- and middle-income countries (2022) (0)
- Sympathetic inputs regulate adaptive thermogenesis in brown adipose tissue through cAMP-Salt inducible kinase axis (2018) (0)
- Microsoft Word-TRP32.Text.RLW2.5 (2009) (0)
- SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses (2018) (0)
- Regulation of HIV-1 Latency via SMYD2-Mediated Histone Methylation (2017) (0)
- Title : SARS-CoV-2 variants of concern have acquired mutations associated with an 1 increased spike cleavage 2 3 (2021) (0)
- Signaling snapshots of 5-HT 2B serotonin receptor activated by the prototypical psychedelic LSD (2022) (0)
- HBV rewires liver cancer signaling by altering PP2A complexes (2023) (0)
- Low expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication (2022) (0)
- Correction: Thioredoxin-related protein 32 is an arsenite-regulated thiol reductase of the proteasome 19 S particle. (2020) (0)
- A systems approach to infectious disease (2020) (0)
- Tat protein recruits a ligase to reorganize the 7SK snRNP for transcriptional activation. (2018) (0)
- Deficiency in Galectin-3, -8, and -9 impairs immunity to chronic Mycobacterium tuberculosis infection but not acute infection with multiple intracellular pathogens (2022) (0)
- Abstract P6-06-01: Analyzing the physical and functional protein interaction landscape of breast cancer (2019) (0)
- MerlinS13 phosphorylation controls meningioma Wnt signaling and magnetic resonance imaging features (2023) (0)
- The functional landscape of the human phosphoproteome (2019) (0)
- Abstract PR04: HER3 crosstalk with HPV16-E6E7 is a feedback resistance mechanism to PI3K-targeted therapies in head and neck cancer (2017) (0)
- Transcription Factor GATA4 Regulates Cell Type–Specific Splicing Through Direct Interaction With RNA in Human Induced Pluripotent Stem Cell–Derived Cardiac Progenitors (2022) (0)
- How can systems approaches help us understand and treat infectious disease? (2022) (0)
- Abstract 1317: Multi-scale mapping of the physical and functional architecture of the cancer cell (2018) (0)
- Supporting Online Material for Rewiring of Genetic Networks in Response to DNA Damage (2010) (0)
- Editor's Note: Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer. (2022) (0)
- BioEssays – Next Issue (2014) (0)
- Genome‐wide screens in yeast reveal that diverse cellular pathways influence the toxicity of various neurodegenerative disease‐associated misfolded proteins (2010) (0)
- Abstract A13: Identification of evolutionarily conserved genetic interactions in DNA mismatch repair (2013) (0)
- Systems approaches for understanding the HIV-host functional interface (2012) (0)
- Influenza virus infection causes global RNAPII termination defects (2018) (0)
- Abstract PR14: A multiscale map of recurrently mutated systems in cancer (2020) (0)
- Individual Lysine Acetylations on the N Terminus of Saccharomyces cerevisiaeH2A.Z Are Highly but Not (2010) (0)
- Author response: SUMO is a pervasive regulator of meiosis (2021) (0)
- Mandegar et al - Supplemental (2016) (0)
- Brown adipocyte NOSEMPE promotes nonmitochondrial thermogenesis and improves systemic metabolism through ATF4 activation (2019) (0)
- A balancing act: Interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans. (2022) (0)
- Guiding Philosophies for Running a Lab (2014) (0)
- Transcription‐linked kinases that regulate histone lysine methylation states (2006) (0)
- Author response: Genetic analysis reveals functions of atypical polyubiquitin chains (2018) (0)
- Conservation and structural analysis of the Xenopus laevis phospho-proteome (2014) (0)
- Global proteomic profiling of primary macrophages during M. tuberculosis infection identifies TAX1BP1 as a mediator of autophagy targeting (2019) (0)
- A tyrosine kinase protein interaction map reveals targetable EGFR network oncogenesis in lung cancer (2020) (0)
- Abstract B48: Identification of novel drug interactions with MYC via a quantitative chemical-genetic interaction map (2015) (0)
- Genetic Interaction mapping of essential genes in Saccharomyces cerevisiae (2007) (0)
- Physical host‐pathogen networks (2012) (0)
- Correction: Thioredoxin-related protein 32 is an arsenite-regulated thiol reductase of the proteasome 19 S particle. (2020) (0)
- A new strategy to beat Ebola virus at its own game (2019) (0)
- EPCO-01. EPIGENETIC REPROGRAMMING SHAPES THE MOLECULAR AND CELLULAR LANDSCAPE OF SCHWANNOMA (2022) (0)
- W 07 on : Integrative Dynamic Analyses of Large Biomedical Network Data List of abstracts (2014) (0)
- TITLE: An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an 1 inactive conformation 2 (2020) (0)
- Abstract 197: Transcription Factor Interactome in Human iPS-derived Cardiac Progenitors is Enriched for Proteins Associated With Congenital Heart Disease (2019) (0)
- Knowing the Players to Understand the Game (0)
- Abstract P1-05-31: Studying the interactome of breast cancer: The cancer cell map initiative (2017) (0)
- Abstract PR07: Functional analysis of diverse oncogenic driver mutations using an isogenic cell line library identifies novel drug responses and alterations in metabolism (2015) (0)
- SARS-CoV-2 Spike in complex with neutralizing nanobody Nb6 (2020) (0)
- Building a super elongation complex for HIV A better understanding of the host cell protein complex that helps HIV replicate inside cells offers the possibility of new therapeutic targets. (2013) (0)
- Systems approaches reveal shared pathways affected in SARS-CoV-2 infection and cancer (2020) (0)
- Abortively Infected with HIV IFI 16 DNA Sensor Is Required for Death of Lymphoid CD 4 T Cells (2014) (0)
- Abstract 2308: The protein interaction landscape of breast cancer (2021) (0)
- Extensive negative genetic interactions with npl3 Δ connect NPL3 to chromatin biology. (2012) (0)
- Link between histone deubiquitination and protection of telomeres (2005) (0)
- Correction: A Chemical-Genomic Screen of Neglected Antibiotics Reveals Illicit Transport of Kasugamycin and Blasticidin S (2017) (0)
- Prokaryotic Systems Biology (2015) (0)
- The Kinase Module of the Mediator regulates cell cycle re-entry and transcriptional response following DNA damage (2023) (0)
- Abstract C88: Genomics, advocacy, and emerging therapeutics to address triple-negative breast cancer (TNBC) outcome disparities. (2016) (0)
- corrigendum: The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II (2005) (0)
- Biophysical basis of cellular multi-specificity encoded in a model molecular switch (2020) (0)
- Author Correction: SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses (2018) (0)
- 2 A MULTI-CONDITIONAL GeNeTIC INTeRACTION MAP TO DISSeCT DNA DAMAGe ReSPONSe PAThwAyS (2013) (0)
- The nuclear transport machinery controls the localization of Mad 1 p and modulates its function in the spindle assembly checkpoint (2005) (0)
- Epigenetic reprogramming shapes the cellular landscape of schwannoma (2022) (0)
- Evolutionarily conserved genetic interactions with budding and fission yeast MutS identify orthologous relationships in mismatch repair-deficient cancer cells (2014) (0)
- Fate of telomere entanglements is dictated by the timing of anaphase midregion nuclear envelope breakdown (2023) (0)
- Publisher Correction: Evolution of enhanced innate immune evasion by SARS-CoV-2 (2022) (0)
- Author response: The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation (2018) (0)
- Publisher Correction: Evolution of enhanced innate immune evasion by SARS-CoV-2 (2022) (0)
- Abstract 2078: A multiscale map of DNA damage response in human cells (2021) (0)
- BIOINFORMATICS Ensemble non-negative matrix factorization methods for clustering protein–protein interactions (2008) (0)
- Mutations in yhiT enable utilization of exogenous pyrimidine intermediates in Salmonella enterica serovar Typhimurium. (2007) (0)
- Structure of anti-SARS-CoV-2 Spike nanobody mNb6 (2020) (0)
- Author Correction: SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses (2018) (0)
- Abstract B44: A systems approach combining genomics, advocacy, and emerging novel therapeutics to address triple-negative breast cancer (TNBC) outcomes disparities (2015) (0)
- The CCL2 Chemokine Promotes Early Seeding of the Latent HIV Reservoir (2021) (0)
- Abstract PR15: Functional analysis of diverse oncogenic driver mutations using an isogenic cell line library identifies novel drug responses and alterations in metabolism (2015) (0)
- Leveraging Modeling and Simulation to Optimize the Therapeutic Window for Epigenetic Modifier Drugs (2022) (0)
- Mapping genetic interactions in cancer: a road to rational combination therapies (2019) (0)
- Abstract PHB03: A hierarchical model of DNA repair inferred from omics-scale genetic interaction data reveals the dynamics of DNA damage induction (2020) (0)
- Structure snapshot: Integrative structure determination of histones H3 and H4 using genetic interactions. (2022) (0)
- Abstract B45: Studying the interactome of breast cancer: The cancer cell map initiative (2018) (0)
- Method Towards accurate imputation of quantitative genetic interactions (2010) (0)
- Assen Roguev , Revealed by an Epistasis Map in Fission Yeast Conservation and Rewiring of Functional Modules (2008) (0)
- Abstract PO017: HBV alters YAP regulation in liver cancer by remodeling PP2A complexes (2022) (0)
- Cell mapping initiatives aim to uncover hidden pathways of disease (2017) (0)
- Modeling of Protein Complex Architectures using Combinatorial Genetic Perturbations (2019) (0)
- Spindle Checkpoint Factors Promote NHEJ 1 Spindle Checkpoint Factors Bub 1 and Bub 2 Promote DNA 1 Double Strand Break Repair by Non-Homologous End Joining 2 3 (2015) (0)
- Abstract 223: Using physical, genetic and integrated cancer cell maps to investigate head and neck cancer and breast cancer (2020) (0)
- Abstract 4891: Hepatitis B virus remodels host protein interaction networks to generate distinct cellular dependencies (2020) (0)
This paper list is powered by the following services:
Other Resources About Nevan Krogan
What Schools Are Affiliated With Nevan Krogan?
Nevan Krogan is affiliated with the following schools:
