Nial J. Wheate
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Australian chemist
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Nial J. Wheatechemistry Degrees
Chemistry
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Organic Chemistry
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Chemistry
Why Is Nial J. Wheate Influential?
(Suggest an Edit or Addition)According to Wikipedia, Nial J. Wheate is an Australian pharmaceutical chemist and author at the University of Sydney. Career After completing high school at Copland College in Canberra, Australia, Wheate was appointed an officer in the Royal Australian Navy. He attended the Australian Defence Force Academy, where he studied for a Bachelor of Science degree double majoring in chemistry, graduating in 1997 with Honours Class I for his degree. After a short appointment as a Visiting Military Scholar, Wheate undertook a PhD under the supervision of Associate Professor J. Grant Collins within the School of Physical, Environmental and Mathematical Sciences, at University College, University of New South Wales, with a thesis "Platinum Anticancer Drugs" in 2001.
Nial J. Wheate's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The status of platinum anticancer drugs in the clinic and in clinical trials. (2010) (1316)
- The side effects of platinum-based chemotherapy drugs: a review for chemists. (2018) (713)
- Gold Nanoparticles for the Improved Anticancer Drug Delivery of the Active Component of Oxaliplatin (2010) (705)
- The potential of cucurbit[n]urils in drug delivery (2011) (229)
- Multi-nuclear platinum complexes as anti-cancer drugs (2003) (222)
- DNA intercalators in cancer therapy: organic and inorganic drugs and their spectroscopic tools of analysis. (2007) (205)
- The state-of-play and future of platinum drugs. (2015) (194)
- Cucurbit[n]uril binding of platinum anticancer complexes. (2006) (138)
- Improving platinum(II)-based anticancer drug delivery using cucurbit[n]urils. (2008) (126)
- Multi-nuclear platinum complexes encapsulated in cucurbit[n]uril as an approach to reduce toxicity in cancer treatment. (2004) (123)
- Cisplatin drug delivery using gold-coated iron oxide nanoparticles for enhanced tumour targeting with external magnetic fields (2012) (107)
- Novel platinum(II)-based anticancer complexes and molecular hosts as their drug delivery vehicles. (2007) (102)
- Multi-nuclear platinum drugs: a new paradigm in chemotherapy. (2005) (88)
- Cisplatin-tethered gold nanoparticles that exhibit enhanced reproducibility, drug loading, and stability: a step closer to pharmaceutical approval? (2012) (87)
- Cucurbit[7]uril encapsulated cisplatin overcomes cisplatin resistance via a pharmacokinetic effect. (2012) (86)
- Evaluation of anionic half generation 3.5-6.5 poly(amidoamine) dendrimers as delivery vehicles for the active component of the anticancer drug cisplatin. (2011) (83)
- Studies of the mechanism of action of platinum(II) complexes with potent cytotoxicity in human cancer cells. (2009) (83)
- The effect of ancillary ligand chirality and phenanthroline functional group substitution on the cytotoxicity of platinum(II)-based metallointercalators. (2007) (81)
- Encapsulation of platinum(II)-based DNA intercalators within cucurbit[6,7,8]urils (2007) (78)
- Solid state stabilisation of the orally delivered drugs atenolol, glibenclamide, memantine and paracetamol through their complexation with cucurbit[7]uril. (2010) (77)
- The ex vivo neurotoxic, myotoxic and cardiotoxic activity of cucurbituril-based macrocyclic drug delivery vehicles. (2014) (76)
- Substituted beta-cyclodextrin and calix[4]arene as encapsulatory vehicles for platinum(II)-based DNA intercalators. (2008) (71)
- Executive functions predict conceptual learning of science. (2016) (70)
- Degradation of bidentate-coordinated platinum(II)-based DNA intercalators by reduced L-glutathione. (2008) (68)
- A chemical preformulation study of a host-guest complex of cucurbit[7]uril and a multinuclear platinum agent for enhanced anticancer drug delivery. (2009) (59)
- A cisplatin slow-release hydrogel drug delivery system based on a formulation of the macrocycle cucurbit[7]uril, gelatin and polyvinyl alcohol. (2014) (55)
- Magnetised Thermo Responsive Lipid Vehicles for Targeted and Controlled Lung Drug Delivery (2012) (46)
- Synthesis, Characterisation and Biological Activity of Chiral Platinum(II) Complexes (2006) (43)
- Cucurbit[n]urils as excipients in pharmaceutical dosage forms (2016) (40)
- Host-Guest Complexes of Carboxylated Pillar[n]arenes With Drugs. (2016) (37)
- Examination of cucurbit[7]uril and its host-guest complexes by diffusion nuclear magnetic resonance. (2008) (36)
- Host–guest complexes of the antituberculosis drugs pyrazinamide and isoniazid with cucurbit[7]uril (2010) (36)
- Synthesis, cytotoxicity, cell uptake and DNA interstrand cross-linking of 4,4'-dipyrazolylmethane-linked multinuclear platinum anti-cancer complexes. (2001) (35)
- Anionic PAMAM dendrimers as drug delivery vehicles for transition metal-based anticancer drugs. (2009) (35)
- Correction: The side effects of platinum-based chemotherapy drugs: a review for chemists. (2018) (34)
- Synthesis, processing and solid state excipient interactions of cucurbit[6]uril and its formulation into tablets for oral drug delivery. (2010) (34)
- Side-on binding of p-sulphonatocalix[4]arene to the dinuclear platinum complex trans-[{PtCl(NH3)2}2mu-dpzm]2+ and its implications for anticancer drug delivery. (2009) (33)
- The Host-Guest Chemistry of Proflavine with Cucurbit[6,7,8]urils (2007) (32)
- Polyamide platinum anticancer complexes designed to target specific DNA sequences. (2006) (27)
- Potential adenine and minor groove binding platinum complexes. (2004) (26)
- Combining aspects of the platinum anticancer drugs picoplatin and BBR3464 to synthesize a new family of sterically hindered dinuclear complexes; their synthesis, binding kinetics and cytotoxicity. (2012) (25)
- DNA binding of the anti-cancer platinum complex trans-[{Pt(NH3)2Cl}2μ-dpzm]2+ (2003) (24)
- Cucurbit[n]uril: A New Molecule in Host–Guest Chemistry (2006) (23)
- Diffusion-based studies on the self-stacking and nanorod formation of platinum(II) intercalators. (2009) (22)
- A 1H NMR study of the oligonucleotide binding of [(en)Pt(mu-dpzm)2Pt(en)]Cl4. (2000) (22)
- Macrocycles as drug-enhancing excipients in pharmaceutical formulations (2021) (20)
- Evidence for a Role of Executive Functions in Learning Biology (2014) (20)
- Folding of dinuclear platinum anticancer complexes within the cavity of para-sulphonatocalix[4]arene (2012) (19)
- Microwave synthesis of cucurbit[n]urils. (2010) (16)
- Comparative macrocycle binding of the anticancer drug phenanthriplatin by cucurbit[n]urils, β-cyclodextrin and para-sulfonatocalix[4]arene: a 1H NMR and molecular modelling study (2017) (15)
- Analysis of montmorillonite clay as a vehicle in platinum anticancer drug delivery (2014) (15)
- Rationalising sequence selection by ligand assemblies in the DNA minor groove: the case for thiazotropsin A (2012) (15)
- Demonstration of In Vitro Host-Guest Complex Formation and Safety of para-Sulfonatocalix[8]arene as a Delivery Vehicle for Two Antibiotic Drugs. (2018) (13)
- Diffusion Coefficient of Cucurbit[n]urils (n = 6 or 7) at Various Concentrations, Temperatures, and pH† (2009) (13)
- Thermal Rearrangement of N-Substituted Pyrazoles to 4,4'-Dipyrazolylmethane and 1,1,2-(4,4',4''-Tripyrazolyl)ethane (2001) (13)
- DNA-based aptamer fails as a simultaneous cancer targeting agent and drug delivery vehicle for a phenanthroline-based platinum(II) complex. (2013) (12)
- Topical Cream-Based Dosage Forms of the Macrocyclic Drug Delivery Vehicle Cucurbit[6]uril (2014) (12)
- Synthesis of DNA-sequence-selective hairpin polyamide platinum complexes. (2007) (12)
- Cucurbit [7] uril encapsulated cisplatin overcomes resistance to cisplatin induced by Rab25 overexpression in an intraperitoneal ovarian cancer model (2015) (12)
- The binding of [(en)Pt(mu-dpzm)2Pt(en)]4+ to G/C-rich regions of DNA. (2001) (11)
- Synthesis, DNA binding and cytotoxicity of isohelical DNA groove binding platinum complexes. (2000) (11)
- Chemical factors affecting cucurbit[n]uril formulation into ocular dosage forms: excipient binding, solubility, corneal permeability and antibiotic encapsulation (2014) (11)
- Platinum drugs in the Australian cancer chemotherapy healthcare setting: Is it worthwhile for chemists to continue to develop platinums? (2019) (11)
- Loading of a Phenanthroline-Based Platinum(ii) Complex onto the Surface of a Carbon Nanotube via π–π Stacking (2016) (10)
- Nanoparticles: the future for platinum drugs or a research red herring? (2012) (10)
- (4,7-Dimethyl-1,10-phenanthroline)(ethylenediamine)platinum(II) dichloride tris(deuterium oxide) solvate (2006) (9)
- Patterns of platinum drug use in an acute care setting: a retrospective study (2018) (8)
- para-Sulfonatocalix[4]arene and polyamidoamine dendrimer nanocomplexes as delivery vehicles for a novel platinum anticancer agent. (2017) (8)
- Evaluation of the antidepressant therapeutic potential of isocyanine and pseudoisocyanine analogues of the organic cation decynium-22. (2017) (8)
- A chemical perspective on the clinical use of platinum-based anticancer drugs. (2022) (7)
- Demonstration of the first known 1:2 host-guest encapsulation of a platinum anticancer complex within a macrocycle (2019) (6)
- Encapsulation of cisplatin by cucurbit[7]uril decreases the neurotoxic and cardiotoxic side effects of cisplatin (2013) (6)
- Synthesis of a heterodinuclear ruthenium(II)-platinum(II) complex linked by l-cysteine methyl ester (2007) (4)
- An evaluation of garlic products available in Australian pharmacies–From the label to the laboratory (2018) (3)
- Analysis of the interaction of para-sulfonatocalix[8]arene with free amino acids and a six residue segment of β-amyloid peptide as a potential treatment for Alzheimer’s disease (2019) (3)
- Medicinal Cannabis for the Treatment of Anxiety Disorders: a Narrative Review (2022) (2)
- Determining the Ibuprofen Concentration in Liquid-Filled Gelatin Capsules To Practice Collecting and Interpreting Experimental Data, and Evaluating the Methods and Accuracy of Quality Testing (2017) (2)
- Poisonings with ADHD medication in children under the age of 5 years in Australia: a retrospective study, 2004–2019 (2022) (1)
- A review of environmental contamination and potential health impacts on aquatic life from the active chemicals in sunscreen formulations (2022) (1)
- Over-the-counter cough and cold medicines: reported poisonings of children before and after the 2012 and 2020 labelling changes in Australia. (2023) (1)
- Medicinal cannabis for patients with chronic non-cancer pain: analysis of safety and concomitant medications. (2022) (1)
- Opioid exposures in children under 5 years of age (2004–2019): A retrospective study of calls to Australia's largest poisons information centre (2021) (1)
- An Analysis for Adulteration and Contamination of Over-the-Counter Weight-Loss Products (2021) (1)
- Amide coupling reaction for the synthesis of bispyridine-based ligands and their complexation to platinum as dinuclear anticancer agents. (2014) (1)
- Comparative host–guest complex formation of the Alzheimer’s drug memantine with para-sulfonatocalix[n]arenes (n = 4 or 8) (2021) (0)
- Magnetised Thermo Responsive Lipid Vehicles for Targeted and Controlled Lung Drug Delivery (2012) (0)
- Index Abstracts (2014) (0)
- Platinum-based Chemotherapy: Are we any Closer to a Cure for Cancer? (2005) (0)
- Potential factors that can affect the performance of undergraduate pharmacy research students: a descriptive study (2023) (0)
- Pharmaceutical Drug Design, Formulation, Testing, and Use (2020) (0)
- Using Spectroscopic Techniques to Examine Drug– DNA Interactions (2011) (0)
- Medicinal cannabis for Australian patients with chronic refractory pain including arthritis (2022) (0)
- RESEARCH ARTICLE: Development of a pharmacy undergraduate laboratory class which combines compounding, natural products, and analytical chemistry (2019) (0)
- Aqueous compatibility of 15 pharmaceutical antimicrobial preservatives with the macrocycles cucurbit[7]uril and para-sulfonatocalix[4]arene (2021) (0)
- Hospitalised poisonings in Australian children: a 10-year retrospective study (2023) (0)
- PAMAM dendrimers as drug delivery vehicles for platinum anticancer drugs (2009) (0)
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