Nicholas Chiorazzi

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Nicholas Chiorazzi

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#287

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#1080

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#1108

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Nicholas Chiorazzi

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Cell Biology

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Genetics

#857

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#951

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Molecular Biology

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Engineering
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Nicholas Chiorazzi's Degrees

Masters Biochemistry Stanford University

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Nicholas Chiorazzi's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia. (1999) (2703)
Relation of Gene Expression Phenotype to Immunoglobulin Mutation Genotype in B Cell Chronic Lymphocytic Leukemia (2001) (1215)
Chronic lymphocytic leukemia. (1984) (1048)
Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors. (1998) (947)
iwCLL guidelines for diagnosis, indications for treatment, response assessment, and supportive management of CLL. (2018) (874)
In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells. (2005) (658)
The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo. (2012) (605)
High Mobility Group Box Protein 1: An Endogenous Signal for Dendritic Cell Maturation and Th1 Polarization (2004) (450)
Multiple Distinct Sets of Stereotyped Antigen Receptors Indicate a Role for Antigen in Promoting Chronic Lymphocytic Leukemia (2004) (443)
B cell chronic lymphocytic leukemia: lessons learned from studies of the B cell antigen receptor. (2003) (413)
B cell receptor signaling in chronic lymphocytic leukemia. (2013) (409)
Stereotyped B-cell receptors in one-third of chronic lymphocytic leukemia: a molecular classification with implications for targeted therapies. (2012) (376)
B-cell chronic lymphocytic leukemia cells express a surface membrane phenotype of activated, antigen-experienced B lymphocytes. (2002) (370)
Unmutated and mutated chronic lymphocytic leukemias derive from self-reactive B cell precursors despite expressing different antibody reactivity. (2005) (357)
Production of autoantibodies by CD5-expressing B lymphocytes from patients with chronic lymphocytic leukemia (1989) (311)
High mobility group box chromosomal protein 1: a novel proinflammatory mediator in synovitis. (2002) (296)
Accumulation of Clonally Related B Lymphocytes in the Cerebrospinal Fluid of Multiple Sclerosis Patients1 (2000) (269)
Cellular origin(s) of chronic lymphocytic leukemia: cautionary notes and additional considerations and possibilities. (2011) (268)
Remarkably similar antigen receptors among a subset of patients with chronic lymphocytic leukemia. (2004) (256)
Synthesis and secretion of multiple forms of beta 2-interferon/B-cell differentiation factor 2/hepatocyte-stimulating factor by human fibroblasts and monocytes. (1988) (251)
Regulation of the immune response by sex hormones. I. In vitro effects of estradiol and testosterone on pokeweed mitogen-induced human B cell differentiation. (1988) (245)
CD38 and chronic lymphocytic leukemia: a decade later. (2011) (222)
Chronic Lymphocytic Leukemia Cells Recognize Conserved Epitopes Associated with Apoptosis and Oxidation (2008) (218)
A novel adoptive transfer model of chronic lymphocytic leukemia suggests a key role for T lymphocytes in the disease. (2011) (211)
Strikingly homologous immunoglobulin gene rearrangements and poor outcome in VH3-21-using chronic lymphocytic leukemia patients independent of geographic origin and mutational status. (2005) (211)
Ia-bearing T lymphocytes in man. Their identification and role in the generation of allogeneic helper activity (1978) (210)
Telomere length and telomerase activity delineate distinctive replicative features of the B-CLL subgroups defined by immunoglobulin V gene mutations. (2004) (202)
CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB x NZW F1 mice. (2003) (196)
T cell helper defect in patients with chronic lymphocytic leukemia. (1979) (195)
Chronic lymphocytic leukemia antibodies with a common stereotypic rearrangement recognize nonmuscle myosin heavy chain IIA. (2008) (185)
Microenvironmental influences in chronic lymphocytic leukaemia: the role of antigen stimulation (2008) (181)
Induction of in vitro differentiation and immunoglobulin synthesis of human leukemic B lymphocytes (1978) (178)
B cell receptors in TCL1 transgenic mice resemble those of aggressive, treatment-resistant human chronic lymphocytic leukemia. (2006) (178)
CD38 expression labels an activated subset within chronic lymphocytic leukemia clones enriched in proliferating B cells. (2007) (177)
Clonal expansion within the CD4+CD57+ and CD8+CD57+ T cell subsets in chronic lymphocytic leukemia. (1997) (173)
Natural killer cell activity and lymphocyte subsets in parenteral heroin abusers and long-term methadone maintenance patients. (1989) (173)
Many chronic lymphocytic leukemia antibodies recognize apoptotic cells with exposed nonmuscle myosin heavy chain IIA: implications for patient outcome and cell of origin. (2010) (173)
Somatic diversification and selection of immunoglobulin heavy and light chain variable region genes in IgG+ CD5+ chronic lymphocytic leukemia B cells (1995) (152)
Anti-CD20/CD3 T cell–dependent bispecific antibody for the treatment of B cell malignancies (2015) (151)
In vivo intraclonal and interclonal kinetic heterogeneity in B-cell chronic lymphocytic leukemia. (2009) (151)
BTK inhibition results in impaired CXCR4 chemokine receptor surface expression, signaling and function in chronic lymphocytic leukemia (2015) (146)
Activation-induced cytidine deaminase in chronic lymphocytic leukemia B cells: expression as multiple forms in a dynamic, variably sized fraction of the clone. (2003) (145)
Chromosomal mapping of members of the cdc2 family of protein kinases, cdk3, cdk6, PISSLRE, and PITALRE, and a cdk inhibitor, p27Kip1, to regions involved in human cancer. (1995) (141)
Cell proliferation and death: forgotten features of chronic lymphocytic leukemia B cells. (2007) (138)
Intraclonal Complexity in Chronic Lymphocytic Leukemia: Fractions Enriched in Recently Born/Divided and Older/Quiescent Cells (2011) (138)
Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations. (2016) (133)
Evidence for a defect in "switch" T cells in patients with immunodeficiency and hyperimmunoglobulinemia M. (1986) (132)
A different ontogenesis for chronic lymphocytic leukemia cases carrying stereotyped antigen receptors: molecular and computational evidence (2010) (124)
Immunoglobulin Heavy Chain Variable Region Gene Replacement as a Mechanism for Receptor Revision in Rheumatoid Arthritis Synovial Tissue B Lymphocytes (2000) (122)
Induction of polyclonal antibody synthesis by human allogeneic and autologous helper factors (1979) (116)
Novel genomic alterations and clonal evolution in chronic lymphocytic leukemia revealed by representational oligonucleotide microarray analysis (ROMA). (2009) (113)
Clinical effect of stereotyped B-cell receptor immunoglobulins in chronic lymphocytic leukaemia: a retrospective multicentre study. (2014) (106)
Special characteristics of cellular immune function in normal individuals of the HLA-DR3 type. (1982) (105)
Hapten-specific IgE antibody responses in mice. VI. Selective enhancement of IgE antibody production by low doses of X-irradiation and by cyclophosphamide. (1976) (105)
Heterogeneity of Tonsillar Subepithelial B Lymphocytes, the Splenic Marginal Zone Equivalents1 (2000) (103)
Differentiation Capacity and Other Properties of the Leukemic Cells of Chronic Lymphocytic Leukemia * (1979) (101)
Common nonmutational NOTCH1 activation in chronic lymphocytic leukemia (2017) (100)
Identification of outcome-correlated cytokine clusters in chronic lymphocytic leukemia. (2011) (99)
Use of Epstein-Barr virus-transformed B cell lines for the generation of immunoglobulin-producing human B cell hybridomas (1982) (99)
Distinct patterns of novel gene mutations in poor-prognostic stereotyped subsets of chronic lymphocytic leukemia: the case of SF3B1 and subset #2 (2013) (98)
Hapten-specific IgE antibody responses in mice. VII. Conversion of IgE "non-responder" strains to IgE "responders" by elimination of suppressor T cell activity. (1977) (98)
Chronic Lymphocytic Leukemia B Cells Can Undergo Somatic Hypermutation and Intraclonal Immunoglobulin VHDJH Gene Diversification (2002) (96)
Immune function in systemic lupus erythematosus. Impairment of in vitro T-cell proliferation and in vivo antibody response to exogenous antigen. (1979) (95)
Direct in vivo Evidence for Increased Proliferation of CLL Cells in Lymph Nodes Compared to Bone Marrow and Peripheral Blood (2016) (90)
Stimulation of human B lymphocytes by antibodies to IgM and IgG: functional evidence for the expression of IgG on B-lymphocyte surface membranes. (1980) (89)
The pattern and distribution of immunoglobulin VH gene mutations in chronic lymphocytic leukemia B cells are consistent with the canonical somatic hypermutation process. (2004) (89)
CD5 and immunoglobulin V gene expression in B-cell lymphomas and chronic lymphocytic leukemia. (1990) (87)
Implications of new prognostic markers in chronic lymphocytic leukemia. (2012) (85)
A role for the polymorphism at position 247 of the beta2-glycoprotein I gene in the generation of anti-beta2-glycoprotein I antibodies in the antiphospholipid syndrome. (1999) (83)
Subepithelial B cells in the human palatine tonsil. I. Morphologic, cytochemical and phenotypic characterization (1996) (81)
Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia (2015) (81)
Monoclonal antibodies with specificity for hairy cell leukemia cells. (1982) (78)
Immunoglobulin V region gene use and structure suggest antigen selection in AIDS-related primary effusion lymphomas (1999) (78)
Distinct homotypic B-cell receptor interactions shape the outcome of chronic lymphocytic leukaemia (2017) (78)
B‐Cell Chronic Lymphocytic Leukemia, a Clonal Disease of B Lymphocytes with Receptors that Vary in Specificity for (Auto)antigens (2005) (77)
Leukemia cell proliferation and death in chronic lymphocytic leukemia patients on therapy with the BTK inhibitor ibrutinib. (2017) (76)
Restricted immunoglobulin VH region repertoire in chronic lymphocytic leukemia patients with autoimmune hemolytic anemia. (1996) (75)
Familial systemic lupus erythematosus in males. (1983) (72)
Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations. (2015) (71)
B lymphocytes in humans express ZAP‐70 when activated in vivo (2006) (67)
Th17 and non-Th17 interleukin-17-expressing cells in chronic lymphocytic leukemia: delineation, distribution, and clinical relevance (2012) (66)
Identification of three subgroups of B cell chronic lymphocytic leukemia based upon mutations of BCL-6 and IgV genes (2000) (66)
B Cell Chronic Lymphocytic Leukemia (2003) (65)
The global transcriptional maturation program and stimuli-specific gene expression profiles of human myeloid dendritic cells. (2003) (63)
A potential role for antigen selection in the clonal evolution of Burkitt's lymphoma. (1994) (63)
Helper factors derived from autologous mixed lymphocyte cultures. (1980) (62)
Chronic lymphocytic leukaemia: a disease of activated monoclonal B cells. (2010) (61)
FCRL2 expression predicts IGHV mutation status and clinical progression in chronic lymphocytic leukemia. (2008) (61)
B Cell Proliferation, Somatic Hypermutation, Class Switch Recombination, and Autoantibody Production in Ectopic Lymphoid Tissue in Murine Lupus1 (2009) (60)
Analysis of single nucleotide polymorphisms in the promoter region of interleukin-10 by denaturing high-performance liquid chromatography. (2005) (59)
Different spectra of recurrent gene mutations in subsets of chronic lymphocytic leukemia harboring stereotyped B-cell receptors (2016) (58)
Examples of in vivo isotype class switching in IgM+ chronic lymphocytic leukemia B cells. (1996) (58)
Induction of T cell-dependent B cell differentiation by anti-CD3 monoclonal antibodies. (1987) (57)
EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia (2017) (56)
Higher-order connections between stereotyped subsets: implications for improved patient classification in CLL. (2020) (56)
VH gene usage by family members affected with chronic lymphocytic leukaemia (1999) (55)
Dendritic cell activating peptides induce distinct cytokine profiles. (2006) (55)
Biology and treatment of chronic lymphocytic leukemia. (2003) (52)
IGHV-unmutated and IGHV-mutated chronic lymphocytic leukemia cells produce activation-induced deaminase protein with a full range of biologic functions. (2012) (52)
Determining the clinical course and outcome in chronic lymphocytic leukemia. (2003) (52)
The Human Marginal Zone B Cell (2003) (52)
An antigen characteristic of hairy cell leukemia cells is expressed on certain activated B cells. (1984) (50)
Evidence for progenitors of chronic lymphocytic leukemia B cells that undergo intraclonal differentiation and diversification. (1996) (50)
T cell antigen receptors in autoimmunity. (1988) (49)
S152 (CD27). A modulating disulfide-linked T cell activation antigen. (1988) (49)
Clonal expansion is a characteristic feature of the B-cell repertoire of patients with rheumatoid arthritis (1999) (48)
Regulation of IgE antibody production by serum molecules. I. Serum from complete Freund's adjuvant-immune donors suppresses irradiation-enhanced IgE production in low responder mouse strains. (1978) (48)
Excessive antigen reactivity may underlie the clinical aggressiveness of chronic lymphocytic leukemia stereotyped subset #8. (2015) (48)
Preparation and characterization of monoclonal antibodies recognizing three distinct differentiation antigens (BL1, BL2, BL3) on human B lymphocytes. (1984) (48)
Clonal heterogeneity in chronic lymphocytic leukemia cells: superior response to surface IgM cross-linking in CD38, ZAP-70-positive cells (2008) (48)
Chronic lymphocytic leukemia: A tale of one or two signals? (2012) (47)
TSP50, a possible protease in human testes, is activated in breast cancer epithelial cells. (2002) (45)
Characterization of structurally defined epitopes recognized by monoclonal antibodies produced by chronic lymphocytic leukemia B cells. (2009) (44)
Subepithelial B cells in the human palatine tonsil. II. Functional characterization (1996) (43)
Maintenance of B lymphocyte‐related clones in the cerebrospinal fluid of multiple sclerosis patients (2003) (43)
Expression of CD5 and CD38 by human CD5− B cells: Requirement for special stimuli (1994) (42)
TLR-9 and IL-15 Synergy Promotes the In Vitro Clonal Expansion of Chronic Lymphocytic Leukemia B Cells (2015) (41)
Lack of intraclonal diversification in Ig heavy and light chain V region genes expressed by CD5+IgM+ chronic lymphocytic leukemia B cells: a multiple time point analysis. (1998) (41)
Simultaneous flow cytometric analysis of cell surface markers and telomere length: analysis of human tonsilar B cells. (2001) (41)
Adenosine signaling mediates hypoxic responses in the chronic lymphocytic leukemia microenvironment. (2016) (40)
Alternative splicing of CD79a (Ig-alpha/mb-1) and CD79b (Ig-beta/B29) RNA transcripts in human B cells. (1995) (40)
Recent advances in the molecular biology and immunobiology of chronic lymphocytic leukemia. (2004) (40)
Autoantigen can promote progression to a more aggressive TCL1 leukemia by selecting variants with enhanced B-cell receptor signaling (2013) (39)
Evidence for differential responsiveness of human CD5+ and CD5− B cell subsets to T cell‐independent mitogens (1991) (39)
Immunological properties of conjugates of ragweed pollen antigen E with methoxypolyethylene glycol or a copolymer of D-glutamic acid and D- lysine (1979) (39)
Induction of Human Antibody Responses In Vitro with Emphasis on Allogeneic Helper Factors (1979) (38)
Evolving view of the in-vivo kinetics of chronic lymphocytic leukemia B cells. (2006) (38)
Association between B-cell receptor responsiveness and disease progression in B-cell chronic lymphocytic leukemia: results from single cell network profiling studies (2013) (37)
Psoriasis and Raynaud's phenomenon associated with autoantibodies to U1 and U2 small nuclear ribonucleoproteins. (1986) (37)
IL-4 rescues surface IgM expression in chronic lymphocytic leukemia. (2016) (37)
Temporal shifts from Sm to ribonucleoprotein reactivity in systemic lupus erythematosus. (1985) (36)
IGHV1-69 B Cell Chronic Lymphocytic Leukemia Antibodies Cross-React with HIV-1 and Hepatitis C Virus Antigens as Well as Intestinal Commensal Bacteria (2014) (36)
Isolation of malignant B cells from patients with chronic lymphocytic leukemia (CLL) for analysis of cell proliferation: validation of a simplified method suitable for multi-center clinical studies. (2010) (36)
Lifespan is prolonged in autoimmune-prone (NZB/NZW) F1 mice fed a diet supplemented with indole-3-carbinol. (2003) (35)
Stimulation of a subset of normal resting T lymphocytes by a monoclonal antibody to a crossreactive determinant of the human T cell antigen receptor (1985) (34)
T cell antiidiotypic antibodies reveal differences between two human leukemias (1984) (34)
A Systematic Search Into The Role Of IGHV Gene Replacement In Shaping The Immunoglobulin Repertoire Of Chronic Lymphocytic Leukemia (2013) (34)
IGLV3-21*01 is an inherited risk factor for CLL through the acquisition of a single-point mutation enabling autonomous BCR signaling (2020) (34)
IGF1R as druggable target mediating PI3K-δ inhibitor resistance in a murine model of chronic lymphocytic leukemia. (2019) (33)
Two human neonatal IgM antibodies encoded by different variable-region genes bind the same linear peptide: evidence for a stereotyped repertoire of epitope recognition. (1999) (33)
A Selective Novel Peroxisome Proliferator-Activated Receptor (PPAR)-α Antagonist Induces Apoptosis and Inhibits Proliferation of CLL Cells In Vitro and In Vivo (2015) (33)
Textbook of the autoimmune diseases (2000) (32)
Hapten specific IgE antibody responses in mice. V. Differential resistance of IgE and IgG B lymphocytes to X-irradiation. (1976) (32)
Serial phenotypic, cytogenetic and molecular genetic studies in Richter's syndrome: demonstration of lymphoma development from the chronic lymphocytic leukaemia cells (1993) (32)
Highly heterogeneous nature of delta-aminolevulinate dehydratase (ALAD) deficiencies in ALAD porphyria. (2001) (32)
Induction if immunological tolerance to the major antigenic determinant of penicillin: a therapeutic approach to penicillin allergy. (1976) (32)
Methicillin-resistant Staphylococcal enterocolitis. (1998) (31)
Naturally occurring antibodies reactive with sperm proteins: apparent deficiency in AIDS sera. (1985) (31)
Novel Method for High-Throughput Full-Length IGHV-D-J Sequencing of the Immune Repertoire from Bulk B-Cells with Single-Cell Resolution (2017) (30)
Biased Usage of Variable and Constant‐Region Ig Genes by IgG+, CD5+ Human Leukemic B Cells a (1992) (30)
Regulatory role of circulating monocytes in the differentiative and proliferative responses of human B lymphocytes. (1980) (29)
Genomic imbalance defines three prognostic groups for risk stratification of patients with chronic lymphocytic leukemia (2014) (28)
Constitutive and activation-inducible cyclooxygenase-2 expression enhances survival of chronic lymphocytic leukemia B cells. (2006) (28)
The human Ig-beta cDNA sequence, a homologue of murine B29, is identical in B cell and plasma cell lines producing all the human Ig isotypes. (1993) (27)
Whole-exome sequencing in relapsing chronic lymphocytic leukemia : clinical impact of recurrent RPS 15 mutations (2016) (27)
Chronic lymphocytic leukemia cells diversify and differentiate in vivo via a nonclassical Th1-dependent, Bcl-6-deficient process. (2016) (27)
Combined BTK and PI3Kδ Inhibition with Acalabrutinib and ACP-319 Improves Survival and Tumor Control in CLL Mouse Model (2017) (26)
B-Cell Chronic Lymphocytic Leukemia (B-CLL) Cells Express Antibodies Reactive with Antigenic Epitopes Expressed on the Surface of Common Bacteria. (2006) (25)
What is the CLL B-lymphocyte? (1996) (25)
Similarities and Differences Between the Light and Heavy Chain Ig Variable Region Gene Repertoires in Chronic Lymphocytic Leukemia (2006) (23)
Leukemia-cell proliferation and disease progression in patients with early stage chronic lymphocytic leukemia (2017) (23)
Chronic Lymphocytic Leukemia with Mutated IGHV4-34 Receptors: Shared and Distinct Immunogenetic Features and Clinical Outcomes (2017) (23)
Cell interactions between histoincompatible T an B lymphocytes. IX. The failure of histoincompatible cells is not due to suppression and cannot be circumvented by carrier-priming T cells with allogeneic macrophages. (1976) (22)
Igs Expressed by Chronic Lymphocytic Leukemia B Cells Show Limited Binding-Site Structure Variability (2013) (22)
mechanisms of disease Chronic Lymphocytic Leukemia (2010) (22)
CD5+ B cells with the features of subepithelial B cells found in human tonsils (2007) (22)
A Cyclooxygenase-2/Prostaglandin E2 Pathway Augments Activation-Induced Cytosine Deaminase Expression within Replicating Human B Cells (2010) (22)
SLAMF6 as a Regulator of Exhausted CD8+ T Cells in Cancer (2019) (21)
Colocalization of Antigen-Specific B and T Cells within Ectopic Lymphoid Tissue following Immunization with Exogenous Antigen1 (2008) (21)
Indole-3-carbinol improves survival in lupus-prone mice by inducing tandem B- and T-cell differentiation blockades. (2009) (21)
Diversification of the Ig Variable Region Gene Repertoire of Synovial B Lymphocytes by Nucleotide Insertion and Deletion (2003) (21)
T-cell independent, B-cell receptor-mediated induction of telomerase activity differs among IGHV mutation-based subgroups of chronic lymphocytic leukemia patients. (2012) (20)
Enhanced expression of mRNA for nuclear factor κB1 (p50) in CD34+ cells of the bone marrow in rheumatoid arthritis (2006) (20)
Immunoglobulin heavy variable (IGHV) genes and alleles: new entities, new names and implications for research and prognostication in chronic lymphocytic leukaemia (2014) (20)
CD180 functions in activation, survival and cycling of B chronic lymphocytic leukaemia cells (2011) (19)
Anti-CD23 monoclonal antibodies: comparisons of epitope specificities and modulating capacities for IgE binding and production. (1993) (19)
Murine genetically engineered and human xenograft models of chronic lymphocytic leukemia. (2014) (19)
Binding of CLL Subset 4 B Cell Receptor Immunoglobulins to Viable Human Memory B Lymphocytes Requires a Distinctive IGKV Somatic Mutation (2017) (19)
A seven-gene expression panel distinguishing clonal expansions of pre-leukemic and chronic lymphocytic leukemia B cells from normal B lymphocytes (2015) (18)
Somatic CLL mutations occur at multiple distinct hematopoietic maturation stages: documentation and cautionary note regarding cell fraction purity (2017) (18)
Apoptosis of Burkitt's lymphoma cells induced by specific interaction of surface IgM with a self-antigen: implications for lymphomagenesis in acquired immunodeficiency syndrome. (1996) (18)
Myeloid-derived suppressor cell subtypes differentially influence T-cell function, T-helper subset differentiation, and clinical course in CLL (2021) (17)
Recognition of antigen-specific B-cell receptors from chronic lymphocytic leukemia patients by synthetic antigen surrogates. (2014) (17)
Conversion of systemic lupus erythematosus to common variable hypogammaglobulinemia. (1989) (17)
No improvement in long-term survival over time for chronic lymphocytic leukemia patients in stereotyped subsets #1 and #2 treated with chemo(immuno)therapy (2017) (17)
Interaction between anti-DNA and anti-DNA-binding protein autoantibodies in cryoglobulins from sera of patients with systemic lupus erythematosus (1986) (16)
Clinical and laboratory parameters that define clinically relevant B-CLL subgroups. (2005) (16)
The CD38 Ectoenzyme Family: Advances in Basic Science and Clinical Practice (2006) (15)
Enhanced outgrowth of EBV-transformed chronic lymphocytic leukemia B cells mediated by coculture with macrophage feeder cells. (2012) (15)
In vitro stimulation of human tonsillar subepithelial B cells: requirement for interaction with activated T cells (2001) (15)
Surface Expression of Bcl-2 in Chronic Lymphocytic Leukemia and Other B-Cell Leukemias and Lymphomas Without a Breakpoint t(14;18) (2008) (14)
Torque Teno Virus 10 Isolated by Genome Amplification Techniques from a Patient with Concomitant Chronic Lymphocytic Leukemia and Polycythemia Vera (2011) (14)
The CD38 ectoenzyme family: advances in basic science and clinical practice. (2006) (14)
Identification and characterization of distinct IL-17F expression patterns and signaling pathways in chronic lymphocytic leukemia and normal B lymphocytes (2015) (13)
The involvement of microRNA in the pathogenesis of Richter syndrome (2018) (13)
Polyreactive Monoclonal Antibodies Synthesized by Some B-CLL Cells Recognize Specific Antigens on Viable and Apoptotic T Cells. (2006) (13)
Polyreactive Monoclonal Antibodies Synthesized by Some B-CLL Cells Recognize Specific Antigens on Viable and Apoptotic T Cells. (2006) (13)
Monoclonal IgM, IgG, and IgA human rheumatoid factors produced by synovial tissue-derived, EBV-transformed B cell lines. (1993) (12)
AID Overlapping and Polη Hotspots Are Key Features of Evolutionary Variation Within the Human Antibody Heavy Chain (IGHV) Genes (2020) (12)
Celebrating 20 Years of IGHV Mutation Analysis in CLL (2020) (12)
Chronic Lymphocytic Leukemia Monitoring with a Lamprey Idiotope-Specific Antibody (2013) (12)
Internal standard-based analysis of microarray data2—Analysis of functional associations between HVE-genes (2011) (12)
Long-term pulmonary blood flow alterations following relief of partial bronchial obstruction. (1974) (11)
A p53 Axis Regulates B Cell Receptor-Triggered, Innate Immune System-Driven B Cell Clonal Expansion (2012) (11)
Targeting Stereotyped B Cell Receptors from Chronic Lymphocytic Leukemia Patients with Synthetic Antigen Surrogates* (2016) (11)
Chronic lymphocytic leukemia: new concepts for future therapy. (2010) (11)
Chronic lymphocytic leukemia: a proliferation of B cells at two distinct stages of differentiation. (2000) (11)
Rewiring of sIgM-Mediated Intracellular Signaling through the CD180 Toll-like Receptor (2015) (11)
Mechanistic Insights into CpG DNA and IL-15 Synergy in Promoting B Cell Chronic Lymphocytic Leukemia Clonal Expansion (2018) (11)
Functional Evidence from Deuterated Water Labeling That the Bruton Tyrosine Kinase Inhibitor Ibrutinib Blocks Leukemia Cell Proliferation and Trafficking and Promotes Leukemia Cell Death in Patients with Chronic Lymphocytic Leukemia and small Lymphocytic Lymphoma (2014) (11)
Effects of prostaglandin E2 on p53 mRNA transcription and p53 mutagenesis during T‐cell‐independent human B‐cell clonal expansion (2014) (10)
The complete sequence of the human CD79b (lgβ/B29) gene: identification of a conserved exon/intron organization, immunoglobulin-like regulatory regions, and allelic polymorphism (2004) (10)
AID in Chronic Lymphocytic Leukemia: Induction and Action During Disease Progression (2021) (10)
CXCL13 plasma levels function as a biomarker for disease activity in patients with chronic lymphocytic leukemia (2020) (10)
Musashi 2 influences chronic lymphocytic leukemia cell survival and growth making it a potential therapeutic target (2021) (10)
Mutation Pattern of Paired Immunoglobulin Heavy and Light Variable Domains in Chronic Lymphocytic Leukemia B Cells (2011) (10)
A combination of an anti-SLAMF6 antibody and ibrutinib efficiently abrogates expansion of chronic lymphocytic leukemia cells (2016) (9)
Automated shape-based clustering of 3D immunoglobulin protein structures in chronic lymphocytic leukemia (2018) (9)
Phenotypic and Functional Characterization of Human Tonsillar Subepithelial (SE) B Cells a (1997) (9)
Chronic lymphocytic leukemia immunoglobulins display bacterial reactivity that converges and diverges from auto-/poly-reactivity and IGHV mutation status. (2016) (9)
Post-Transformation IGHV-IGHD-IGHJ Mutations in Chronic Lymphocytic Leukemia B Cells: Implications for Mutational Mechanisms and Impact on Clinical Course (2021) (9)
On Statistical Modeling of Sequencing Noise in High Depth Data to Assess Tumor Evolution (2017) (9)
Dendritic Cells from Chronic Lymphocytic Leukemia Patients Are Normal Regardless of Ig V Gene Mutation Status (2004) (8)
Biochemical characterization and purification of human B cell stimulatory factor (BSF) (1985) (8)
An IgG1-like bispecific antibody targeting CD52 and CD20 for the treatment of B-cell malignancies. (2019) (8)
Lack of deleterious somatic mutations in the CD95 gene of plasmablasts from systemic lupus erythematosus patients and autoantibody‐producing cell lines (2002) (8)
Dual Inhibition of PI3K-Delta and Gamma By Duvelisib (IPI-145) Impairs CLL B- and T-Cell Migration, Survival and Proliferation in a Murine Xenograft Model Using Primary Chronic Lymphocytic Leukemia Cells (2015) (8)
IgH and L chain variable region gene sequence analyses of twelve synovial tissue-derived B cell lines producing IgA, IgG, and IgM rheumatoid factors structure/function comparisons of antigenic specificity, V gene sequence, and Ig isotype. (1995) (8)
AID overexpression leads to aggressive murine CLL and nonimmunoglobulin mutations that mirror human neoplasms. (2021) (7)
Chromosomal localization, genomic structure, and allelic polymorphism of the human CD79a (lg-αmb-1) gene (2004) (7)
FCRL 2 expression predicts IGHV mutation status and clinical progression in chronic lymphocytic leukemia (2008) (7)
In Vivo modeling of Resistance to PI3Kδ Inhibitor Treatment Using EµTCL1-Tg Tumor Transfer Model (2016) (7)
Differential immunomodulation by anti-CD2 monoclonal antibodies of anti-CD3-induced T cell activation: dependence upon the individual anti-CD3 monoclonal antibody used for activation. (1988) (7)
An Innate Natural Antibody Is Reactive with a Cryptic Sequence of Lactoferrin Exposed on Sperm Head Surface (1997) (7)
Induction of a ragweed-specific allergic state in Ir-gene-restricted nonresponder mice (1977) (6)
Human Monoclonal Antibodies as Probes to Study Autoimmune and Allergic Disorders (1986) (6)
Peptides That Bind Specifically to an Antibody from a Chronic Lymphocytic Leukemia Clone Expressing Unmutated Immunoglobulin Variable Region Genes (2013) (6)
Roncella, S. et al. Apoptosis of Burkitt's Lymphoma cells induced by specific interaction surface IgM with a self-antigen: implications for lymphomagenesis in acquired immunodeficiency syndrome. Blood 88, 599-608 (1996) (6)
Heterogeneous p53 mutations in a Burkitt lymphoma from an AIDS patient with monoclonal c‐myc and VDJ rearrangements (1997) (6)
Anti-inflammatory curcumin inhibits AID expression within cycling human B cells (96.21) (2010) (6)
p15, A nuclear-associated protein of human sperm: Identification of four variants and their occurrence in normal and abnormal seminal cells (1983) (6)
B cell receptor isotypes differentially associate with cell signaling, kinetics, and outcome in chronic lymphocytic leukemia (2021) (6)
Dual Inhibition of PI3K-δ and PI3K-γ By Duvelisib Eliminates CLL B Cells, Impairs CLL-Supporting Cells, and Overcomes Ibrutinib Resistance in a Patient-Derived Xenograft Model (2018) (6)
Engraftment of CLL-Derived T Cells in NSG Mice Is Feasible, Can Support CLL Cell Proliferation, and Eliminates the Need for Third Party Antigen Presenting Cells (2011) (6)
Analysis of stepwise genetic changes in an AIDS‐related Burkitt's lymphoma (2000) (6)
Hapten-specific IgE antibody responses in mice. VIII. A possible new mechanism by which anti-lymphocyte serum enhances IgE antibody synthesis in vivo. (1977) (6)
Fc receptor-like 2 (FCRL2) is a novel marker of low-risk CLL and refines prognostication based on IGHV mutation status (2019) (5)
A Novel Disulfide-Linked Cell Surface Molecule Present on Resting and Activated Human T Lymphocytes (1986) (5)
In Vivo Labeling of Newly Synthesized DNA Suggests That the CD38+ Fraction Is Enriched in Proliferating Cells within a Clone of Chronic Lymphocytic Leukemia B Cells. (2006) (5)
Mechanism for IL-15–Driven B Cell Chronic Lymphocytic Leukemia Cycling: Roles for AKT and STAT5 in Modulating Cyclin D2 and DNA Damage Response Proteins (2019) (5)
Chronic Lymphocytic Leukemia Patients with IGHV Genes Carrying Only Silent Mutations Have A Longer Time From Diagnosis to Initial Therapy Than Patients Expressing B-Cell Receptors with No Somatic Mutations (2011) (5)
Cytoplasmic myosin exposed apoptotic cells appear with caspase-3 activation and enhance CLL cell viability (2015) (5)
Promiscuous Antigen Reactivity May Underlie Clinical Aggressiveness and Increased Risk for Richter's Syndrome in Chronic Lymphocytic Leukemia with Stereotyped IGHV4-39/IGKV1(D)-39 B Cell Receptors (2012) (5)
Multi-Parameter Phenotypic Analysis of Members of Chronic Lymphocytic Leukemia Clones Identifies Distinct Proliferative and Resting/Re-Entry Compartments with Discrete Gene Expression Profiles. (2009) (5)
B-cell chronic lymphocytic leukemia/lymphoma (2013) (5)
CD38 Expression Identifies an Active Subset of Proliferating Cells within the Clonal Population in Chronic Lymphocytic Leukemia Patients (In Vitro Analysis). (2006) (5)
Evidence for Allelic Exclusion of p53 within Single Sorted Human B Cells (2011) (4)
Measurement of Leukemic B-Cell Growth Kinetics in Patients with Chronic Lymphocytic Leukemia. (2018) (4)
The Composition of the B Cell Receptor Repertoire In 7428 Cases of Chronic Lymphocytic Leukemia: One Third Stereotyped, Two Thirds Heterogeneous - What Does This Mean? (2010) (4)
The Number of Overlapping AID Hotspots in Germline IGHV Genes Is Inversely Correlated with Mutation Frequency in Chronic Lymphocytic Leukemia (2017) (4)
Inhibition of reactive oxygen species limits expansion of chronic lymphocytic leukemia cells (2017) (4)
Hapten-specific IgE antibody responses in mice. IX. Suppression of IgE antibody production by passive transfer of T cells from adjuvant-primed syngeneic mice. (1979) (4)
Potential Relevance of B-cell Maturation Pathways in Defining the Cell(s) of Origin for Chronic Lymphocytic Leukemia. (2021) (4)
FcγRIIb expression in early stage chronic lymphocytic leukemia (2017) (4)
Where is the biology of CLL leading us? (2010) (4)
Aortic dissection in a patient with chronic hemodialysis. (1974) (4)
A Detailed Analysis of Parameters Supporting the Engraftment and Growth of Chronic Lymphocytic Leukemia Cells in Immune-Deficient Mice (2021) (3)
CLL intraclonal fractions exhibit established and recently acquired patterns of DNA methylation. (2020) (3)
Kinetic Measurement of Leukemia-Cell Proliferation Rate By Deuterium Labeling Predicts Time to Initial Treatment of Patients with Chronic Lymphocytic Leukemia (2014) (3)
75 GENE EXPRESSION PROFILING CAN DISTINGUISH PHYSIOLOGIC B-CELL CHRONIC LYMPHOCYTIC LEUKEMIA CLONAL EXPANSIONS FROM PRELEUKEMIC AND LEUKEMIC CLONES. (2006) (3)
AID overexpression leads to aggressive murine CLL and non-Ig mutations that mirror human neoplasms. (2021) (3)
Ibrutinib Inhibits Concomitant TLR and BCR- Driven Proliferation of Chronic Lymphocytic Leukemia Cells and Overrides the Supportive Survival-Promoting Effects of Microenvironmental Signals (2014) (3)
Murine TCL1 CLL Cells with B-Cell Receptors Specific for the Autoantigen Phosphatidylcholine Have a Selective Advantage During Adoptive Transfer (2010) (3)
Human B-cell-stimulatory-factor production by both T4+ and T8+ lymphocytes. (1984) (3)
Expression Levels of a Single Gene, Lymphoid Enhancer Binding Factor 1, Discriminates CLL B-Cells from Other B-Cell Malignancies. (2007) (3)
TSP 50 , A Possible Protease in Human Testes , Is Activated in Breast Cancer Epithelial Cells 1 (2001) (3)
A monovalent C mu 4-specific ligand enhances the activation of human B cells by membrane IgM cross-linking ligands. (1995) (3)
CLL Stereotyped IGHV-D-J Rearrangements Can Be Detected Throughout Normal B-Cell Developmental Stages in Aged People When Using Ultra-Deep, Next Generation Sequencing Techniques (2016) (3)
Description and partial characterization of a nucleolar RNA-associated autoantigen defined by a human monoclonal antibody (1987) (3)
Validating The Prognostic Significance Of FCRL2 In Predicting IGHV Mutation Status, Clinical Disease Progression, and Survival In CLL (2013) (3)
Recurrent hematuria. Occurrence in a white woman with sickle cell trait. (1974) (3)
and Treatment of Chronic Lymphocytic Leukemia (2003) (3)
Chromosomal localization, genomic structure, and allelic polymorphism of the human CD79 alpha (Ig-alpha/mb-1) gene. (1994) (3)
PGE2 Upregulates Activation-Induced Cytosine Deaminase (AID) in Human B Lymphoblasts (34.12) (2009) (2)
In Vivo Isotype Class Switching in CD5+ Chronic Lymphocytic Leukemia B Cells a (1995) (2)
CLL B Cells Develop Resistance to Ibrutinib By Reinvigorating the IL-4R - IL-4 Axis Blocked By Bruton's Tyrosine Kinase Inhibitors Including Acalabrutinib and Zanubrutinib (2019) (2)
Stimulation of lymphocytes with antibodies to surface membrane-bound antigen receptors. (1987) (2)
Identification of Distinct Cytokine and Chemokine Clusters That Correlate with Outcome In B-Cell Chronic Lymphocytic Leukemia: Implications for Disease Pathogenesis (2010) (2)
Complementation Studies in Fanconi Anemia (1989) (2)
Lenalidomide Promotes The Expansion Of CD8 T Cells With An Effector Memory Phenotype In a Murine Xenograft Model Of Chronic Lymphocytic Leukemia (2013) (2)
Evidence for B Cell Oligoclonality in the Blood and Joints of Patients with Rheumatoid Arthritisa (1997) (2)
GRN163L Inhibits Telomerase Activity in B-CLL Cells. (2005) (2)
CLL-like monoclonal B cell lymphocytosis displays an increased inflammatory signature that is reduced in early stage chronic lymphocytic leukemia. (2021) (2)
Chronic Lymphocytic Leukemia Cells Recognize Conserved Epitopes Associated with Apoptosis and Catabolic Chemical Modifications (2008) (2)
Multiplex accurate sensitive quantitation (MASQ) with application to minimal residual disease in acute myeloid leukemia (2020) (2)
Identification of HSP‐60 as the specific antigen of IgM produced by BRG‐lymphoma cells (1999) (2)
The BCRs Expressed by Leukemia Cells from TCL1 Transgenic Mice Resemble Those of Unmutated B-CLL. (2005) (2)
B lymphocytes and autoimmunity (1997) (2)
Subepithelial B cells of the human tonsil. (1997) (2)
Expression and function of cathelicidin hCAP18/LL-37 in chronic lymphocytic leukemia. (2020) (2)
In Vivo Labeling of Dividing Chronic Lymphocytic Leukemia B Cells Suggests That CXCR4 and CD5 Define the Clonal Subfraction That Recently Proliferatead and Emigrated from a Solid Tissue (2008) (2)
DNA Hypomethylation Leads to Aberrant Expression of PD-1 in Chronic Lymphocytic Leukemia (2012) (2)
Induction of Apoptosis in CLL by Peptides Binding the B-Cell Antigen Receptor in Vitro (2008) (2)
Ibrutinib Disrupts IL-4R - IL-4 Axis By Inhibiting IL-4R Signaling and Reversing Th2/Th1 Polarization through Diminished CLECL1 in CLL B Cells (2017) (2)
Somatic Hypermutation In Stereotyped Subset 4 BCRs/mAbs of CLL Patients, Expressing IGHV4-34 gene, Edit Anti-DNA Reactivity (2010) (2)
B-CLL Antibodies Comprised of Stereotypic VH1-69, D3-16, and JH3 Rearrangements Immunoprecipitate Cellular Protein(s). (2006) (2)
In Vivo Evidence That Ibrutininb Deregulates Chemokine Receptor CXCR4 Surface Membrane Expression and Signaling, Along with Inhibiting B Cell Antigen Receptor Signaling, As Causes for Defective Homing and Impaired Retention of CLL Cells in Tissues (2014) (2)
Ibrutinib Treatment Reduces Myeloid Derived Suppressor Cell Numbers and Function in Chronic Lymphocytic Leukemia (2018) (2)
Soluble Fc Receptor for IgM in Sera From Subsets of Patients With Chronic Lymphocytic Leukemia as Determined by a New Mouse Monoclonal Antibody (2022) (2)
Automated Clustering Analysis of Immunoglobulin Sequences in Chronic Lymphocytic Leukemia Based on 3D Structural Descriptors (2016) (2)
A Different Ontogenesis for CLL Cases Carrying Stereotyped Antigen Receptors: Molecular and Computational Evidence (2008) (2)
CLL-Cell Proliferation Measured by In Vivo Deuterium Labeling in Early Stage Patients and Correlation with Other Prognostic Markers. (2007) (1)
No Improvement In Long-Term Overall Survival After The Introduction Of Chemo(Immuno)Therapy For Chronic Lymphocytic Leukemia Patients Belonging To Stereotyped Subset #2 (2016) (1)
Abstract 3531: Changes in immune cell populations in relapsed/refractory CLL patients treated with a Bruton's Tyrosine Kinase (BTK) Inhibitor, Ibrutinib (PCI-32765), in combination with Bendamustine and Rituximab (BR). (2013) (1)
In CLL, Myeloid-Derived Suppressor Cells and Their Monocytic and Granulocytic Varieties Differ in T-Cell Subset Association and Polarization Induction (2016) (1)
Activated CLL cells regulate IL17F producing Th17 cells in miR155 dependent and outcome specific manners. (2022) (1)
Autologous Human T Cells and Allogeneic Antigen-Presenting Cells Permit Effective Adoptive Transfer of B-CLL Cells Into Immune Deficient Mice. (2009) (1)
Chronic Lymphocytic Leukemia Patients Exhibit Expanded Functional Granulocyte-like Myeloid Derived Suppressor Cells (2014) (1)
Expression of CD38 and High Levels of CD5 Identifies Members of CLL Clones That Have Progressed beyond G1 and Proliferated. (2007) (1)
Correlation of Leukemia-Cell Birth Rate Measured by Heavy Water Labeling with Other Prognostic Markers in Early Stage Chronic Lymphocytic Leukemia. (2009) (1)
Reappraising Immunoglobulin Repertoire Restrictions in Chronic Lymphocytic Leukemia: Focus on Major Stereotyped Subsets and Closely Related Satellites (2016) (1)
Impact of the Types and Relative Quantities of IGHV Gene Mutations in Predicting Prognosis of Patients With Chronic Lymphocytic Leukemia (2022) (1)
Evidence for Alternative Lengthening of Telomeres in Chronic Lymphocytic Leukemia Patients. (2005) (1)
11th International Congress of Immunology (2001) (1)
Highly sensitive detection of small variants in multi-sample ultra-deep tumor sequencing (2017) (1)
B Cells of the Proliferative Fraction of CLL Clones Exhibit Activated B-Cell and Myeloid-Cell Signatures Suggesting Enhanced Antigen-Presentation, Integrin Responsiveness, and IL-4 Receptiveness: Additional Targets for CLL Therapy (2016) (1)
Augmentation by Cytochalasin B of Antigen Receptor‐Mediated Activation of Normal and Malignant Human B Lymphocytes (1990) (1)
A Human Hematopoietic Environment and Autologous T-Cell Growth Support Proliferation of Chronic Lymphocytic Leukemia B Cells in Immune-Deficient Mice (2008) (1)
Single Cell Network Profiling (SCNP) Identifies Altered Signaling Between Patient Risk Groups in B-Cell Chronic Lymphocytic Leukemia (B-CLL). (2012) (1)
Possible Role of Cytokines in the Pathogenesis of Non-Organ Specific Autoimmunity (1992) (1)
2.10 Effect of Sequential Ligation of CD180/RP105 and sIgM on Downstream Signalling in CLL Cells (2011) (1)
Remarkable Differences in Cellular Activation State and Migratory and Proliferative Potential among Clonal Cells Derived from Different Tissues of Chronic Lymphocytic Leukemia Patients. (2006) (1)
CLL Sera Drive Maturation of Normal Monocytes to M2-like Macrophages By Direct and Indirect Mechanisms (2014) (1)
Essential Clinical Immunology: Chronic Lymphocytic Leukemia (2009) (1)
Expression of Angiogenin in Normal B Lymphocytes and B-CLL Cells. (2005) (1)
Association of CXCR4 with IgM and IgD BCR Isotypes: Role in B Cell Malignancies (2018) (1)
The Association for Patient‐Oriented Research (2009) (1)
Anti-CD70 Monoclonal Antibodies Show Efficacy in Preclinical Models for Chronic Lymphoblastic Leukemia (2022) (1)
Miniatures Chronic Lymphocytic Leukemia Monitoring with a Lamprey Idiotope-Speci fi c Antibody (2013) (1)
A spoonful of sugar helps lymphoma cells go up. (2015) (1)
CHAPTER 17 – GENERATION OF PLAQUE-FORMING CELLS: ALLOGENEIC EFFECT AND SIGNIFICANCE OF MONOCYTE REMOVAL1 (1979) (1)
In B-CLL, time to first treatment is dependant on the IgVH gene mutations and expression of CD38 on leukemic cells (2005) (1)
TLR-9 and B-Cell Antigen Receptor Triggering of Primary B Cells From Mantle Cell Lymphoma Induce Cell Proliferation and Telomerase Activity, (2011) (1)
FCRL2 Expression Is Predictive of IgV H Mutation Status and Clinical Progression in Chronic Lymphocytic Leukemia. (2007) (1)
IgM and IgD Differential CLL BCRs Organization and Interaction with Co-Receptors before and during Ibrutinib Therapy (2017) (1)
The Accessory Cell Function of B‐CLL B Cells a (1997) (1)
IgM and IgD Differential CLL BCRs Organization and Interaction with Co-Receptors before and during Ibrutinib Therapy (2017) (1)
C D 5 and Immunoglobulin V Gene Expression in B-Cell Lymphomas and Chronic Lymphocytic Leukemia (2003) (1)
Characterization of structurally deﬁned epitopes recognized by monoclonal antibodies produced by chronic lymphocytic leukemia B cells (2009) (1)
Elevated IL-17 Producing Cells (Th17 and Non-Th17) In Different CLL Microenvironments: Correlation with Overall Survival, Prognostic Relevance and Phenotypic Heterogenity (2010) (1)
Chronic Lymphocytic Leukemia Patients and Eµ-TCL1 Mice Share a Phenotype of Functional Granulocyte-like and Dysfunctional Monocyte-like Myeloid Derived Suppressor Cells (2015) (1)
Human CLL Intraclonal Fractions Differ in Their Abilities to Respond to, Elicit, and Suppress Pro-Engraftment and Growth Signals From Autologous T Cells in a Murine Adoptive Transfer Model (2012) (1)
Btk Inhibitor, PCI-32765, Delays CLL Progression in a TCL1 Adoptive Transfer Model by Impairing Migration and Cell Proliferation (2011) (1)
Efficacy and Safety of Hydroxychloroquine Sulphate In Chronic Lymphocytic Leukemia: Clinical Trial Experience In Untreated Patients (2010) (1)
Intraclonal Complexity Of CLL Fractions In Cell Proliferation Rates, Gene Expression Signatures, and Responses To Autologous T-Cell Help In Peripheral blood and Secondary Lymphoid Tissues (2013) (1)
IgM and IgD Differential CLL BCRs Organization and Interaction with Co-Receptors before and during Ibrutinib Therapy (2017) (1)
CLL: Different ages, dfferent antigen receptor profiles (2013) (1)
IGHV-D-J Ultra-Deep Sequencing Reveals APOBEC and AID Targeted Mutations during Clonal Evolution of CLL in a Xenograft Mouse Model (2014) (1)
The Correlation of APOBEC Gene Family Member Expression with Worse CLL Patient Outcome Suggests a Role in CLL Mutational Evolution (2015) (1)
FcγRIIb-BCR coligation inhibits B-cell receptor signaling in chronic lymphocytic leukemia (2020) (1)
TEXTBOOK OF AUTOIMMUNE DISEASE (2015) (1)
Different Expression of FcgammaRIIb in Chronic Lymphocytic Leukemia and Human Normal B Lymphocytes (2008) (1)
Correlation of IgVH somatic mutation and disease course in chronic lymphocytic leukemia (2008) (1)
73 DIFFERENTIAL INDUCTION OF LEUKEMIA CELL SURVIVAL AND TELOMERASE ACTIVITY BY T-INDEPENDENT AND T-DEPENDENT STIMULATION OF B-CELL CHRONIC LYMPHOCYTIC LEUKEMIA (B-CLL) CELLS. (2004) (0)
Reciprocal Densities of CXCR4 and CD5 Define Subfractions of Chronic Lymphocytic Leukemia Clones Differing in Phenotype and Response to Environmental Stimuli: Towards a Better Definition of Targetable Components of Leukemic Clones (2014) (0)
Crystallographic evidence of autologous recognition by a clonotypic B cell receptor in chronic lymphocytic leukemia (2015) (0)
4.14 Activation-Induced Cytidine Deaminase Expression and Function in CLL is an Independent Risk Factor for Poor Patient Outcome (2011) (0)
Fcgammariib Expression As a Prognostic Marker in Chronic Lymphocytic Leukemia (2015) (0)
4.14 Activation-Induced Cytidine Deaminase Expression and Function in CLL is an Independent Risk Factor for Poor Patient Outcome (2011) (0)
4.14 Activation-Induced Cytidine Deaminase Expression and Function in CLL is an Independent Risk Factor for Poor Patient Outcome (2011) (0)
FCRL2 expression predicts IGHVmutation status and clinical progression in chronic lymphocytic leukemia. Commentary (2008) (0)
Annals of the New York Academy of Sciences: Preface (2003) (0)
Automated shape-based clustering of 3D immunoglobulin protein structures in chronic lymphocytic leukemia (2018) (0)
Lymphocytic Leukemia B Cells Vitro Clonal Expansion of Chronic TLR-9 and IL-15 Synergy Promotes the In (2015) (0)
Recognition Stereotyped Repertoire of Epitope Bind the Same Linear Peptide : Evidence for a Encoded by Different Variable-Region Genes Two Human Neonatal IgM Antibodies (1999) (0)
Fc receptor-like 2 (FCRL2) is a novel marker of low-risk CLL and refines prognostication based on IGHV mutation status (2019) (0)
Subset-Specific Spectra of Recurrent Gene Mutations in Chronic Lymphocytic Leukemia with Stereotyped B-Cell Receptors (2014) (0)
Novel Library Method for High-Throughput Full-Length Sequencing of the Immune Repertoire from Unseparated B-Cells with Single-Cell Resolutionution (2016) (0)
Is Elevated Serum IL-10 in B-CLL Associated with IL-10 Promoter Polymorphisms?. (2005) (0)
Cesano et al. Supplementary appendix (2013) (0)
CCR4:CCL17 interaction supports clonal cell survival and complements BCR- and TLR-9- mediated cell proliferation in chronic lymphocytic leukemia (149.14) (2011) (0)
Equivalents Lymphocytes , the Splenic Marginal Zone Heterogeneity of Tonsillar Subepithelial (2000) (0)
Fate Discrimination of Normal B Cells When Cross-Linked with Anti-IgM Antibodies of Different Affinities and Valence. (2006) (0)
Provision of Human Multimeric sCD40L to Immune Deficient NSG Mice Permits Efficient and Effective Adoptive Transfer and Proliferation of CLL Cells In Vivo (2010) (0)
14 DENDRITIC CELLS GENERATED FROM CLL PATIENTS ARE PHENOTYPICALLY AND FUNCTIONALLY NORMAL AND INDUCE AN IN VITRO RECALL RESPONSE TO AUTOLOGOUS T CELLS FROM VACCINATED PATIENTS. (2004) (0)
Role for p53 in activation-induced cell death of T cell-independent B cell clones (104.16) (2011) (0)
Frequently Occurring B-CLL Antibodies Recognize Apoptotic Cells That Expose Non-Muscle Myosin Heavy Chain IIA (2008) (0)
Matched Pattern Discovery Across Paired Immunoglobulin Heavy and Light Chains in CLL Reveals Unique Subset-Defining Amino Acid Associations (2014) (0)
CLL stereotyped B-cell receptor immunoglobulin sequences are recurrent in the B-cell repertoire of healthy individuals: Apparent lack of central and early peripheral tolerance censoring (2023) (0)
IL-15-driven clonal expansion of TLR9-primed human B-CLL is characterized by activation of AKT and STAT5, downstream elevation of cyclin D2 and repression of DNA damage response mediators, ATM and TP53BP (2019) (0)
CCR4:CCL17 Interaction Influences TLR-9 Mediated Cell Survival and Proliferation In Chronic Lymphocytic Leukemia (2010) (0)
Reactive Oxygen Species and Metabolic Gene Expression Profiling Further Differentiate CXCR4/CD5 Fractions in Chronic Lymphocytic Leukemia (2017) (0)
Activation of Nucleic Acid-Sensing Toll-Like Receptors Induces Proliferation, Cytokine Production, Immunogenic Phenotype, and Plasma Cell Differentiation of CLL Cells and Immunoglobulin Production. (2007) (0)
Activation of Nucleic Acid-Sensing Toll-Like Receptors Induces Proliferation, Cytokine Production, Immunogenic Phenotype, and Plasma Cell Differentiation of CLL Cells and Immunoglobulin Production. (2007) (0)
1.16 Gene Set Enrichment Analysis of CLL Subgroups Defined by Ki-67 Expression (2011) (0)
2.12 Provision of Human Multimeric sCD40L and Interleukin-4 to Immune-Deficient NOD/SCID/γcnull Mice Permits Efficient and Effective Adoptive Transfer and T-Cell–Independent Proliferation of CLL Cells In Vivo (2011) (0)
Facets of Dendritic Cell Maturation: (2003) (0)
Concomitant, T-Independent TLR9-Mediated and BCR-Mediated Activation Provides Signals For Optimal Telomerase Induction In Chronic Lymphocytic Leukemia Cells Regardless Of IGHV Mutation Status (2013) (0)
SLAMF6 signaling in murine chronic lymphocytic leukemia cells (TUM2P.1019) (2015) (0)
Gene Set Enrichment Analysis of Ki-67 high CLL Clones Suggests Complex Interactions of B-Cell Receptor Signaling and Normal Cell Interactions in the Disease (2011) (0)
Targeted Oligonucleotide Array Assessment of Genomic Copy Number Alterations for Risk Stratification in Chronic Lymphocytic Leukemia (2011) (0)
Immune mechanisms and disease (2003) (0)
Occurrence in a White Woman With Sickle Cell Trait (2017) (0)
Th-17/IL-17 Axis in Chronic Lymphocytic Leukemia. (2009) (0)
Improved Outcome of CLL Patients with Leukemic Clones Expressing Mutated IGHV May Not Be Due to An Inability to Bind (auto)Antigen In Vivo (2010) (0)
Evaluation of IGHV Ultra-Deep Sequences for Activation-Induced Deaminase Characteristics in CLL Cells after T Cell Stimulation (2013) (0)
A cyclooxygenase-2 (COX-2) pathway promotes expression of activation-induced cytosine deaminase (AID) within replicating human B cells (84.7) (2010) (0)
Molecular analyses of VH and VL genes used by 7 cases of Primary Effusion Lymphomas (PEL) disclose the presence of somatic mutations indicative of antigen selection. (1998) (0)
rearrangement recognize nonmuscle myosin heavy chain IIA Chronic lymphocytic leukemia antibodies with a common stereotypic (2013) (0)
Preview : Published ahead of advance online publication EGR 2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia (2016) (0)
Binding of CLL B-Cell Receptors to Viable and Apoptotic Human Cells Offers Insight into the Role of Autoantigens in Leukemic Transformation. (2007) (0)
Clonal Heterogeneity in Membrane Expression of CD5 in a Patient with Chronic Lymphocytic Leukemia a (1995) (0)
Detection of Activation-Induced Cytidine Deaminase RNA In CLL Cells Correlates with Shorter Patient Survival and High Numbers of CD38 + Cells (2010) (0)
Aberrant somatic hypermutation and lymphomagenesis (2003) (0)
B cells mediated by coculture with macrophage feeder cells Enhanced outgrowth of EBV-transformed chronic lymphocytic leukemia (2012) (0)
CLL Intraclonal Fractions Defined By Time Since Cell Birth/Division Promote a Leukemia-Supportive, Immune-Tolerant Microenvironment By Distinct Mechanisms (2018) (0)
Suppression of anti-penicillin reaginic antibody responses by penicillin coupled to a "d" amino acid copolymer. Abstr. (1976) (0)
Anti-Inflammatory Curcumin Inhibits Activation-Induced Cytosine Deaminase (AID) within Cycling Normal and CLL B Lymphocytes. (2010) (0)
Musashi 2 Is Overexpressed in Poor Outcome CLL Patients and Their Proliferative Fraction and Silencing This Gene Induces Apoptosis and Increases Cell Adhesion and Movement (2018) (0)
31 GREATER IN VIVO B-CELL CHRONIC LYMPHOCYTIC LEUKEMIA CELL TURNOVER IS ASSOCIATED WITH PROGRESSIVE LEUKEMIC BURDEN. (2004) (0)
Genome Analysis of CLL by Representational Oligonucleotide Microarray Analysis (ROMA) (2006) (0)
Genome-Wide DNA Methylation Landscape Defines IGHV Mutated and Unmutated B Cell Chronic Lymphocytic Leukemias (2012) (0)
Longitudinal Analyses of CXCR4dimCD5brCD19+ Fractions of Chronic Lymphocytic Leukemia Clones Reveal Features Consistent with a Source of Clonal Heterogeneity (2011) (0)
Activated CLL B Cells Variably Modulate microRNA-155 Levels in Naïve CD4+ T Cells, and the Direction and Magnitude of microRNA-155 Change Correlates with Th17 Levels and Clinical Course (2018) (0)
APOBEC gene family expression and hallmarks in chronic lymphocytic leukemia (2017) (0)
CLECL1+ CLL Cells: A Key Subset That Drives CLL Survival and Proliferation and Shapes a Th2-Biased Tumor Microenvironment (2022) (0)
Chystallographic Evidence of Autologous Recognition By a Clonotypic B Cell Receptor in Chronic Lymphocytic Leukemia (2015) (0)
Apparent Involvement Of The Interferon, RNA Processing, and Wnt Signaling Pathways In Monoclonal B Lymphocytosis (2013) (0)
TLR-9 and IL-15-Driven Clonal Expansion of B-CLL Cells (2014) (0)
Preface (2003) (0)
Prostaglandin E2 upregulates p53 mRNA and protein within activated human B lymphocytes (45.17) (2011) (0)
69 MULTIPLE SETS OF STEREOTYPED IMMUNOGLOBULIN VARIABLE REGIONS SUGGEST A ROLE FOR ANTIGEN IN THE EVOLUTION OF B-CLL. (2004) (0)
Maturation and Th1 Polarization Endogenous Signal for Dendritic Cell High Mobility Group Box Protein 1: An (2004) (0)
Expression and function of cathelicidin hCAP18/LL-37 in chronic lymphocytic leukemia (2020) (0)
CD8+ T Cells from Patients with CLL Show Evidence of Granzyme B and Perforin Cytotoxic Capacity, Which Is Enhanced upon Exposure to Exogenous IL2 and/or IL21 (2022) (0)
Elevated Levels of IL-17, MIP-1 β, MIG and ITAC in B-Cell Chronic Lymphocytic Leukemia: Correlation with Prognostic Markers. (2006) (0)
Correction to: Intraclonal Complexity in Chronic Lymphocytic Leukemia: Fractions Enriched in Recently Born/Divided and Older/Quiescent Cells (2022) (0)
629 Chronic Lymphocytic Leukemia B Cells Can Undergo Somatic Hypermutation and Intraclonal Immunoglobulin V H DJ H Gene (2002) (0)
Activation of Human B Lymphocytes by MLR-Derived Helper Factors and Anti-Immunoglobulins (1980) (0)
Not All IGHV3-21 CLL Are Equal : Subset #2 Displays a Distinctive Clinicobiological Profile with Remarkable Similarities to Subset #169, its Close Immunogenetic Relative (2014) (0)
Patterns of Duvelisib-Induced Lymphocytosis in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Including Those with High-Risk Factors Treated in the DUO Trial (2019) (0)
deficiencies in ALAD porphyria -aminolevulinate dehydratase (ALAD) δ Highly heterogeneous nature of (2013) (0)
Extended Survival in CLL Patients Who Discontinued Idelalisib Because of Colitis Correlates with Higher Th17 Levels in Blood and Colon Tissue (2018) (0)
Clinical Impact of Stereotyped Antigen Receptors in Chronic Lymphocytic Leukemia (2014) (0)
Analyses of the Kinetics and Phenotype of Multiple Intraclonal CXCR4/CD5 B Cell Subsets Suggest Differences in Life Cycle Transitioning in CLL (2021) (0)
2.40 Paradoxical Effects of Fc Gamma Receptor IIb Engagement on the Modulation of BCR Signaling in Chronic Lymphocytic Leukemia B Cells (2011) (0)
2.11 Chronic Lymphocytic Leukemia Cells Respond to CD180 Ligation by Alternative Signalling via Akt (PKB) or P38MAPK Pathways (2011) (0)
Co-Culture of CLL Cells with MEACs (Myosin Heavy Chain IIA Exposed Apoptotic Cells) Promotes Viability of Leukemic Clones (2011) (0)
EGR2 Mutations in Chronic Lymphocytic Leukemia: A New Bad Player (2015) (0)
2.9 Pro-Survival Signalling in ‘Responder' CLL Cells After Ligation of CD180 (2011) (0)
Definition of a Prognostic Scoring System for Predicting Clinical Outcome in B-Cell Chronic Lymphocytic Leukemia. (2006) (0)
Ultra-Deep Sequencing of De Novo IGHV Mutations in Activated CLL Cells: Evidence for Activation-Induced Deaminase Function. (2012) (0)
p53 and COX-2 Inhibitors Control the Replication and Viability of Non-Transformed and CLL B Lymphocytes (2008) (0)
Natural antibodies recognize cytoplasmic myosin that is cleaved and transferred to the cell membrane during apoptosis (89.4) (2010) (0)
Chronic Lymphocytic Leukemia B Cells Variably Express Functional Activation-Induced Cytosine Deaminase Protein (2010) (0)
Duvelisib Eliminates CLL B Cells, Impairs CLL-Supporting Cells, and Overcomes Ibrutinib Resistance in a Xenograft Model. (2023) (0)
Origin and Nature of Chronic Lymphocytic Leukemia B Cells (2008) (0)
Abstract 5182: Identifying differential gene expression and splicing events in chronic lymphocytic leukemia patients through whole transcriptome profiling (2014) (0)
Generation of stable human autoantibody-secreting B cell hybridomas (1992) (0)
A cyclooxygenase-2 (COX-2) pathway promotes expression of activation-induced cytosine deaminase (AID) within replicating human B cells (2010) (0)
Identification and Characterization of Peptide Ligands for Stereotyped Subset and Non-Subset B-Cell Receptors of Patients with M- and U-CLL. (2009) (0)
Direct in Vivo Evidence of Increased Chronic Lymphocytic Leukemia Cell Proliferation in Lymph Nodes Compared to Bone Marrow and Peripheral Blood (2012) (0)
4.29 FCRL2 is a Distinct Marker of MT-CLL that Predicts Both Clinical Progression and Survival (2011) (0)
B-CLL Antibodies Encoded by Stereotypic VH1-69, D3-16, and JH3 Rearrangements Immunoprecipitate Non-Muscle Myosin Heavy Chain IIA. (2007) (0)
Over-Expression of Activation-Induced Cytidine Deaminase in TCL1 Mice Leads to the Development of IGHV-Mutated CLL Clones That Associate with More Aggressive Disease (2017) (0)
2.45 CCR4–Ligand Interactions Contribute Pro-Survival and Proliferative Signals to Chronic Lymphocytic Leukemia B Cells (2011) (0)
CLL Cells Can Diversify, Switch, and Differentiate in Response to Autologous T Cell Stimuli Present in a Murine Adoptive Transfer Model (2012) (0)
Structure Variability Binding-Site Leukemia B Cells Show Limited Igs Expressed by Chronic Lymphocytic (2013) (0)
Chronic Lymphocytic Leukemia B Cells Display IgM and IgD Isotype-Restricted Features That Affect Association with Co-Receptors, BCR Signaling, and Leukemic B-Cell Growth In Vivo (2018) (0)
Induction of immunological tolerance to the major antigenic determinant of penicillin : A therapeutic approach to penicillin allergy [ benzylpenicilloyl-poly ( DGlu , Lys ) / IgE reaginic antibodies / bone-marrow-derived lymphocytes / human allergies / immunotherapy ] (0)
Duvelisib Eliminates CLL B Cells, Impairs CLL-Supporting Cells, and Overcomes Ibrutinib Resistance in Preclinical Models (2021) (0)
Many chronic lymphocytic leukemia antibodies bind apoptotic cells with exposed non-muscle myosin heavy chain IIA in a similar manner as natural antibodies (101.13) (2010) (0)
Influence of PGE 2 on Expression of a Functionally-Relevant p53 SNP (Pro72Arg) within Heterozygous Normal Cycling B Cells, (2011) (0)
Differentiation of Leukemic B Lymphocytes in Man (1979) (0)
Hapten specific immuno globulin e antibody responses in mice part 5 differential resistance of immuno globulin e and immuno globulin g bone marrow derived lymphocytes to x irradiation (1976) (0)
PS1160 PATTERNS OF DUVELISIB-INDUCED LYMPHOCYTOSIS IN PATIENTS WITH RELAPSED/REFRACTORY CHRONIC LYMPHOCYTIC LEUKEMIA/SMALL LYMPHOCYTIC LEUKEMIA INCLUDING THOSE WITH HIGH-RISK FACTORS TREATED IN THE DUO TRIAL (2019) (0)
Ig V gene mutation status correlates well with clinical course and outcome regardless of surface membrane isotype expressed by B-CLL cells (2004) (0)
Efficiency of BCR: Anti-BCR Interaction Dictates Cellular Outcomes of Signaling in Chronic Lymphocytic Leukemia Cells (2008) (0)
Improved Prognosis of Chronic Lymphocytic Leukemia (CLL) Patients with Increased IgVH Mutations May Reflect Greater Alteration of the B-Cell Receptor (BCR) Binding Site (2008) (0)
B cell receptor stereotypy makes a clinical difference in CLL:revelations from a multi-institutional series of 4615 cases (2013) (0)
Recurrent Mutations within the Nfkbie gene: A Novel Mechanism for NF-κB Deregulation in Aggressive Chronic Lymphocytic Leukemia (2014) (0)
Immunoglobulin Heavy Chain Variable Genes and Alleles: New Entities, New Names and Implications for Research and Prognostication in CLL (2014) (0)
Preface (1997) (0)
The Response to Surface IgM and IgD Cross-Linking Defines Different Groups of B-CLL. (2005) (0)
High Cell Death Rates at Start of Ibrutinib Therapy Predict for Deeper Remissions in Patients with Chronic Lymphocytic Leukemia (CLL) (2022) (0)
5.35 Btk Inhibitor, PCI-32765, Delays CLL Progression in a TCL1 Adoptive Transfer Model by Impairing Migration and Cell Proliferation (2011) (0)
Gene Expression and Cytokine Analyses Identify Markers of Progression from CLL-like Monoclonal B-Cell Lymphocytosis to Chronic Lymphocytic Leukemia (2019) (0)
Some CLL Cells Bind Myosin-Exposed Apoptotic Cells. Exposure of Cytoplasmic Myosin Results From Transfer of Caspase-3 Dependent Cleavage Products to the Outer Cell Membrane (2010) (0)
Whole Genome Sequencing Comparison of Acute Myeloid Leukemia at Presentation and Remission Predicts Patient Outcome (2022) (0)
Prostaglandin E2 augments p53 mRNA transcription and protein expression in activated human B lymphocytes (109.12) (2012) (0)
Ig V gene mutation status correlates well with clinical course and outcome regardless of surface membrane isotype expressed by B-CLL cells. (2004) (0)
Elevated Binding of Chronic Lymphocytic Leukemia Antibody to a Subset of Apoptotic Cells with Exposed Non-Muscle Myosin Heavy Chain IIA Correlates with Poor Patient Outcome. (2009) (0)
Erratum to: A Selective Novel Peroxisome Proliferator-Activated Receptor (PPAR)-α Antagonist Induces Apoptosis and Inhibits Proliferation of CLL Cells In Vitro and In Vivo (2015) (0)
A Distributed International Patient Data Registry for Hairy Cell Leukemia (2016) (0)
IGHV Gene Replacement in B-Cell Chronic Lymphocytic Leukemia (B-CLL) Occurs at a Frequency Similar to That in Normal B Cells and May Augment Clonal Expansion by Permitting Autogenic/Microbial Clonal Stimulation. (2006) (0)
Overexpression of Activation-Induced Deaminase in TCL1 Mice Leads to the Development of IGHV -Mutated and -Unmutated CLL Clones That Resemble Unique Subsets of Human CLL (2015) (0)
Chronic Lymphocytic Leukemia B Cells Can Undergo Somatic Hypermutation and Intraclonal Immunoglobulin V H DJ H Gene Diversiﬁcation (2002) (0)
High-Resolution Array-Based Comparative Genome Hybridization (CGH) Identifies Novel and Recurrent Regions in CLL. (2008) (0)
Correction to: Intraclonal Complexity in Chronic Lymphocytic Leukemia: Fractions Enriched in Recently Born/Divided and Older/Quiescent Cells (2022) (0)
In Vivo Evidence of in Situ Cell Death Preferentially Occurring in CLL Patients with Minimal Lymphocytosis By the Diminished BCL2 and Loss of T Cell Support after Ibrutinib Treatment (2016) (0)
FcgRIIb-BCR co-ligation inhibits BCR signaling in chronic lymphocytic leukemia (2020) (0)
Synovial B Cells in Rheumatoid Arthritis: Clonal Expansion, Diversification, and Persistence (1999) (0)
System-Driven B Cell Clonal Expansion Receptor-Triggered, Innate Immune A p53 Axis Regulates B Cell (2012) (0)
Abstract 960: Mechanisms underlying primary ibrutinib sensitivity in CLL (2017) (0)
Private and Shared Idiotypic Determinants of the Human T Cell Antigen Receptor (1986) (0)
Integrin Signaling Pathway Is Crucial for the Recently Divided Fraction of CLL Cells and Facilitates Cell Migration in a Disease Progressive Manner (2022) (0)
Combining Expression of Hypervariably Expressed Genes with IGHV Mutation Status Is a More Robust Prognostic Indicator Than Mutation Status Alone in Chronic Lymphocytic Leukemia (2011) (0)
Comparative Density Analyses of B Cell Receptor-Complex Components (Membrane IgM, Membrane IgD, and Stimulatory/Inhibitory Co-Receptors) on Intraclonal Subpopulations of CLL B Cells, before and during Ibrutinib Therapy (2016) (0)
The RNA Binding Protein Musashi 2 Is up-Regulated in the Proliferative B-Cell Fraction of Chronic Lymphocytic Leukemia Clones (2015) (0)
B Cell Chronic Lymphocytic Leukemia (B CLL) Cells Unresponsive to CD180 Ligation Fail to Respond to Anti IgM Stimulation as Well (2010) (0)
Development of novel Sjogren's Syndrome susceptible mouse lines expressing floxed COX-2 within the major Aec2 disease susceptibility region in chromosome 1 (P4016) (2013) (0)
Hypoxia Influences Gene Expression and Growth Characteristics of HS-5 Stromal Cells and Its Interaction with CLL (2012) (0)
Immunoglobulin heavy variable (IGHV) genes and alleles: new entities, new names and implications for research and prognostication in chronic lymphocytic leukaemia (2014) (0)
CLL Cell Viability Promoted by Myosin Heavy Chain IIA Exposed Apoptotic Cells is BTK-dependent (2012) (0)
Chronic Lymphocytic Leukemia. (2004) (0)
CCR4: TARC Interaction Provides Supplementary Pro-Survival and Proliferative Signals to Chronic Lymphocytic Leukemia Cells. (2009) (0)
The RNA-Binding Protein Musashi 2 Is Upregulated in the Proliferative Fraction of CLL Clones, Particularly in U-CLL Patients, and Its Silencing Induces Programmed Cell Death (2016) (0)
IGHV4-34 B-Cell Receptor Immunoglobulins from CLL Stereotyped Subset 4 React with Influenza A Virus: Requirement for IGHV-D-J/Iglv-J Rearrangement and Isotype Switching to IgG (2014) (0)
Evidence for a CD38+ active subset enriched in proliferating cells, within the clonal population in chronic lymphocytic leukemia patients (2007) (0)
CLL with Mutated IGHV4-34 Antigen Receptors Is Clinically Heterogeneous : Antigen Receptor Stereotypy Makes the Difference (2015) (0)
BCRs of Mutated and Unmutated CLL Bind Peptides with Distinct Sequence Features: Evidence from Phage Display Libraries. (2007) (0)
Efficacy of Ibrutinib Monotherapy in Pre-Clinical Mouse Models of Richter Transformation: Ibrutinib Effectively Reduces the Incidence of Richter Transformation but Fails in Treating Transformed Lymphoma, Especially in Primary Lymphoid Tissue (2021) (0)
Differential Expression Genes of CLL Subgroups Defined by Ki67 Expression Level Which Correlated with Clinical Outcome (2010) (0)
3.21 Th17 and non-Th17 IL-17-Expressing Cells in CLL: Delineation, Distribution, and Clinical Relevance (2011) (0)
Molecular Analysis of FcγRIIb-BCR Colligation Signaling in Primary CLL Lymphocytes (2019) (0)
Identification and characterization of distinct IL-17F expression patterns and signaling pathways in chronic lymphocytic leukemia and normal B lymphocytes (2015) (0)
Replicating Human B Cells Cytosine Deaminase Expression within Pathway Augments Activation-Induced 2 A Cyclooxygenase-2/Prostaglandin E (2010) (0)
Remarkably similar antigen receptors in a subset of patients with IgG+ chronic lymphocytic leukemia (2004) (0)
Deletion of Micro RNA-15/16 Clusters Promotes Leukemic Initiation in AML Via the Deregulation of Hematopoietic Progenitors (2022) (0)
2.6 Anti-Inflammatory Curcumin Inhibits Activation-Induced Cytosine Deaminase (AID) within Cycling Normal and CLL B Lymphocytes (2010) (0)
Hapten specific immuno globulin e antibody responses in mice part 6 selective enhancement of immuno globulin e antibody production by low doses of x irradiation and by cyclo phosphamide (1976) (0)
PATTERNS OF DUVELISIB‐INDUCED LYMPHOCYTOSIS IN PATIENTS WITH R/R CLL OR SLL INCLUDING THOSE WITH HIGH‐RISK FACTORS TREATED IN THE DUO TRIAL (2019) (0)
Myelo- and lympho-proliferative disorders (PP-035) (2010) (0)
Next-Generation Sequencing of Human Antibody Repertoires for Exploring B-cell Landscape, Antibody Discovery and Vaccine Development (2020) (0)
Effect of Polymorphisms in p53 Pathway Proteins and B-Chronic Lymphocytic Leukemia Disease Progression, (2011) (0)
Abstract 91: Constitutive aid expression in CLL mouse model leads to disease progression, tumor proliferation and diminished survival (2015) (0)
Coordinated events following TLR-9 and CD122 signaling promote NF-kB/AKT/STAT5-dependent B-CLL clonal expansion (2018) (0)
1452 RESTING T CELL ACTIVATION BY ANTIRECEPTOR (2003) (0)
Surprising Lack of Correlation between CD38 and Time to First Treatment in Chronic Lympocytic Leukemia. (2007) (0)
mouse bladder gene regulation Neurokinin 1 receptors and neprilysin modulation of (2013) (0)
Low Affinity Interaction with CLL B-Cell Receptors Induces Apoptosis by Down-Regulating Mcl-1 and Up-Regulating BimEL. (2007) (0)
On Statistical Modeling of Sequencing Noise in High Depth Data to Assess Tumor Evolution (2017) (0)
PRODUCTION OF AUTOANTIBODIES BY C135-EXPRESSING B LYMPHOCYTES FROM PATIENTS WITH CHRONIC LYMPHOCYTEC LEUKEMIA (2003) (0)
Deciphering the CXCL9-CXCL10-CXCL11/CXCR3 Axis in CLL-like Monoclonal B-Cell Lymphocytosis and Chronic Lymphocytic Leukemia: A New Target for Immune Activation? (2019) (0)
4.20 MatBA™: A Targeted Oligonucleotide Array for the Assessment of Genomic Copy Number Alterations for Risk Stratification in Chronic Lymphocytic Leukemia (2011) (0)
Human B cell subsets in health and disease: phenotypic, functional, and genetic analyses. (1996) (0)
A seven-gene expression panel distinguishing clonal expansions of pre-leukemic and chronic lymphocytic leukemia B cells from normal B lymphocytes (2015) (0)
Identification of Three Unique Clusters of Serum Proteins with Distinctive Functionalities in IGHV-Mutated MBL (2022) (0)
Suppression of ige antibody responses by passive transfer of cfa-immune serum factors. Abstr. (1978) (0)
A novel pro-survival and proliferation-inducing role for CCR4:TARC interaction in chronic lymphocytic leukemia (CLL) B cells (133.4) (2010) (0)
PROGENITORS OF CLL B CELLS 1593 incidence of monoclonal proteins in the serum and urine of chronic lymphocytic leukemia patients (2002) (0)
Serum IgM/Fcmr Interactions Inhibit BCR Signaling and Influence the Cinical Course of CLL (2018) (0)
Serum Proteomic Analyses Suggest That the HMGB1 and Other Inflammatory Pathways Are Operational in MBL and Are Less in Overt CLL (2021) (0)
Gene Expression Profiles Document That Recently- and Previously-Divided CLL Fractions Represent a Continuum but Suggest Differing Modes of Activation for These Fractions in U-CLL and M-CLL (2012) (0)
Charting Unique Signatures of Somatic Hypermutation Amongst Chronic Lymphocytic Leukemia Patients Expressing IGHV4-34 Clonotypic B Cell Receptors (2014) (0)

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