Nicola Stonehouse
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Professor of Molecular Virology at the University of Leeds
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(Suggest an Edit or Addition)According to Wikipedia, Nicola Jane Stonehouse is a British virologist who is a professor in molecular virology at the University of Leeds. Her research investigates viral diseases and the use of RNA aptamers to study viral proteins. She has worked on the development of a novel poliovirus vaccine that makes use of virus-like particles.
Nicola Stonehouse's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Excitation Sculpting in High-Resolution Nuclear Magnetic Resonance Spectroscopy: Application to Selective NOE Experiments (1995) (550)
- Crystal structure of an RNA bacteriophage coat proteinoperator complex (1994) (331)
- The three-dimensional structures of two complexes between recombinant MS2 capsids and RNA operator fragments reveal sequence-specific protein-RNA interactions. (1997) (196)
- Ultrahigh-Quality NOE Spectra (1994) (187)
- A simple, RNA-mediated allosteric switch controls the pathway to formation of a T=3 viral capsid. (2007) (137)
- All Three Domains of the Hepatitis C Virus Nonstructural NS5A Protein Contribute to RNA Binding (2010) (126)
- Cyclophilin A Interacts with Domain II of Hepatitis C Virus NS5A and Stimulates RNA Binding in an Isomerase-Dependent Manner (2011) (123)
- Crystal structures of a series of RNA aptamers complexed to the same protein target (1998) (100)
- Tandem Fusion of Hepatitis B Core Antigen Allows Assembly of Virus-Like Particles in Bacteria and Plants with Enhanced Capacity to Accommodate Foreign Proteins (2015) (95)
- Minimizing Sensitivity Losses in Gradient-Selected 15N-1H HSQC Spectra of Proteins (1994) (90)
- More powerful virus inhibitors from structure-based analysis of HEV71 capsid-binding molecules (2014) (89)
- High-Risk Human Papillomavirus E5 Oncoprotein Displays Channel-Forming Activity Sensitive to Small-Molecule Inhibitors (2012) (86)
- Capsid Protein VP4 of Human Rhinovirus Induces Membrane Permeability by the Formation of a Size-Selective Multimeric Pore (2014) (81)
- Determining the topology of virus assembly intermediates using ion mobility spectrometry-mass spectrometry. (2010) (81)
- An upstream protein-coding region in enteroviruses modulates virus infection in gut epithelial cells (2018) (78)
- Nucleocapsid protein structures from orthobunyaviruses reveal insight into ribonucleoprotein architecture and RNA polymerization (2013) (70)
- Probing sequence-specific RNA recognition by the bacteriophage MS2 coat protein (1995) (69)
- Viral genomic single-stranded RNA directs the pathway toward a T=3 capsid. (2010) (65)
- The Sensitivity of Experiments Which Use Gradient Pulses for Coherence-Pathway Selection (1994) (65)
- Engineering thermal stability in RNA phage capsids via disulphide bonds. (2005) (62)
- The impact of viral RNA on assembly pathway selection. (2010) (60)
- The crystal structure of a high affinity RNA stem-loop complexed with the bacteriophage MS2 capsid: further challenges in the modeling of ligand-RNA interactions. (2004) (59)
- Crystal structures of MS2 coat protein mutants in complex with wild-type RNA operator fragments. (1998) (53)
- Molecular mechanism of RNA-phage morphogenesis. (1993) (50)
- Effects of amino acid substitution on the thermal stability of MS2 capsids lacking genomic RNA (1993) (48)
- Affinity of molecular interactions in the bacteriophage φ29 DNA packaging motor (2006) (48)
- Probing the kinetics of formation of the bacteriophage MS2 translational operator complex: identification of a protein conformer unable to bind RNA. (2001) (47)
- Insights into virus capsid assembly from non‐covalent mass spectrometry (2008) (47)
- Crystal structures of MS2 capsids with mutations in the subunit FG loop. (1996) (46)
- A historical overview of the Pavilion Lake Research Project-Analog science and exploration in an underwater environment (2011) (42)
- Control of crystal growth during enamel maturation. (1989) (40)
- Increasing Type 1 Poliovirus Capsid Stability by Thermal Selection (2016) (40)
- Molecular mechanism of RNA phage morphogenesis. (1994) (37)
- Structural basis of pyrimidine specificity in the MS2 RNA hairpin-coat-protein complex. (2001) (37)
- Dissecting the key recognition features of the MS2 bacteriophage translational repression complex. (1998) (36)
- Crystallographic studies of RNA hairpins in complexes with recombinant MS2 capsids: implications for binding requirements. (1999) (36)
- Evaluation of a range of mammalian and mosquito cell lines for use in Chikungunya virus research (2017) (35)
- FMDV replicons encoding green fluorescent protein are replication competent (2014) (35)
- RNA aptamers for the MS2 bacteriophage coat protein and the wild-type RNA operator have similar solution behaviour. (2000) (34)
- A convenient and accurate method for the measurement of the values of spin-spin coupling constants (1995) (33)
- Structural basis of RNA binding discrimination between bacteriophages Qbeta and MS2. (2006) (33)
- Minimisation of sensitivity losses due to the use of gradient pulses in triple-resonance NMR of proteins (1995) (33)
- Investigating the structural basis of purine specificity in the structures of MS2 coat protein RNA translational operator hairpins. (2002) (31)
- An RNA Aptamer Provides a Novel Approach for the Induction of Apoptosis by Targeting the HPV16 E7 Oncoprotein (2013) (30)
- Formation of Higher-Order Foot-and-Mouth Disease Virus 3Dpol Complexes Is Dependent on Elongation Activity (2011) (29)
- Structural and phenotypic analysis of Chikungunya virus RNA replication elements (2019) (27)
- Analysis of phage MS2 coat protein mutants expressed from a reconstituted phagemid reveals that proline 78 is essential for viral infectivity. (1997) (26)
- Photodynamic inactivation of bacteriophage MS2: The A-protein is the target of virus inactivation. (2018) (24)
- An RNA Aptamer Targets the PDZ-Binding Motif of the HPV16 E6 Oncoprotein (2014) (23)
- Extracellular processing of enamel matrix proteins and the control of crystal growth. (1990) (23)
- Production and purification of chimeric HBc virus-like particles carrying influenza virus LAH domain as vaccine candidates (2017) (23)
- Employing transposon mutagenesis to investigate foot-and-mouth disease virus replication. (2015) (23)
- Using ion mobility spectrometry-mass spectrometry to decipher the conformational and assembly characteristics of the hepatitis B capsid protein. (2013) (22)
- Effects of single nucleotide changes on the binding and activity of RNA aptamers to human papillomavirus 16 E7 oncoprotein. (2011) (21)
- Selection and characterization of RNA aptamers to the RNA-dependent RNA polymerase from foot-and-mouth disease virus. (2006) (21)
- Potent antiviral agents fail to elicit genetically-stable resistance mutations in either enterovirus 71 or Coxsackievirus A16 (2015) (20)
- Genetic economy in picornaviruses: Foot-and-mouth disease virus replication exploits alternative precursor cleavage pathways (2017) (20)
- Assembly Pathway of Hepatitis B Core Virus-like Particles from Genetically Fused Dimers* (2015) (19)
- Deletion of a single hydrogen bonding atom from the MS2 RNA operator leads to dramatic rearrangements at the RNA-coat protein interface. (2000) (19)
- The broad-spectrum antiviral drug arbidol inhibits foot-and-mouth disease virus genome replication. (2019) (19)
- Inhibition of the foot-and-mouth disease virus subgenomic replicon by RNA aptamers (2014) (19)
- The Oxysterol 25-Hydroxycholesterol Inhibits Replication of Murine Norovirus (2019) (18)
- RNA-induced conformational changes in a viral coat protein studied by hydrogen/deuterium exchange mass spectrometry. (2010) (18)
- The Subcellular Localisation of the Human Papillomavirus (HPV) 16 E7 Protein in Cervical Cancer Cells and Its Perturbation by RNA Aptamers (2015) (18)
- YIP1 family member 4 (YIPF4) is a novel cellular binding partner of the papillomavirus E5 proteins (2015) (17)
- Photodynamic inactivation of non-enveloped RNA viruses. (2018) (17)
- Both cis and trans Activities of Foot-and-Mouth Disease Virus 3D Polymerase Are Essential for Viral RNA Replication (2016) (16)
- TMPyP functionalised chitosan membrane for efficient sunlight driven water disinfection (2017) (15)
- Dynamics in the murine norovirus capsid revealed by high-resolution cryo-EM (2020) (15)
- Antimicrobial Peptide LL-37 Facilitates Intracellular Uptake of RNA Aptamer Apt 21-2 Without Inducing an Inflammatory or Interferon Response (2019) (14)
- Comparative Molecular Biology Approaches for the Production of Poliovirus Virus-Like Particles Using Pichia pastoris (2020) (13)
- RNA packing specificity and folding during assembly of the bacteriophage MS2. (2008) (12)
- Dissecting the fine details of assembly of a T=3 phage capsid (2005) (12)
- MicroRNA-106a Inhibits Autophagy Process and Antimicrobial Responses by Targeting ULK1, ATG7, and ATG16L1 During Mycobacterial Infection (2021) (12)
- Recombinant Expression of Tandem-HBc Virus-Like Particles (VLPs). (2018) (12)
- Functional advantages of triplication of the 3B coding region of the FMDV genome (2020) (9)
- IL-17A RNA aptamer: possible therapeutic potential in some cells, more than we bargained for in others? (2014) (9)
- Molecular interactions in the RNA bacteriophage MS2. (1996) (9)
- Improving solvent suppression in jump-return NOESY experiments (1994) (8)
- Probing Bunyavirus N protein oligomerisation using mass spectrometry (2014) (6)
- High-Risk Human Papillomavirus E 5 Oncoprotein Displays Channel-Forming Activity Sensitive to Small-Molecule Inhibitors (2012) (6)
- History and Potential of Hepatitis B Virus Core as a VLP Vaccine Platform (2015) (6)
- Involvement of a Nonstructural Protein in Poliovirus Capsid Assembly (2018) (6)
- YIP 1 family member 4 ( YIPF 4 ) is a novel cellular binding partner of the papillomavirus E 5 proteins (2015) (5)
- Conformational changes in the connector protein complex of the bacteriophage φ29 DNA packaging motor (2009) (5)
- Foot-and-mouth disease virus genome replication is unaffected by inhibition of type III phosphatidylinositol-4-kinases. (2016) (5)
- RNA Multimerisation in the DNA Packaging Motor of Bacteriophage φ29 (2005) (5)
- On the stereoselectivity of nitrone addition to α-diphenylphosphinoylalkenes (1994) (4)
- Generation of Antibodies against Foot-and-Mouth-Disease Virus Capsid Protein VP4 Using Hepatitis B Core VLPs as a Scaffold (2021) (4)
- Structural insight into Pichia pastoris fatty acid synthase (2021) (4)
- Higher-order structures of the foot-and-mouth disease virus RNA-dependent RNA polymerase required for genome replication (2022) (3)
- Acute gastroenteritis and the usage pattern of antibiotics and traditional herbal medications for its management in a Nigerian community (2021) (3)
- Development of an Enzyme-Linked Immunosorbent Assay for Detection of the Native Conformation of Enterovirus A71 (2022) (3)
- High-Resolution Cryo-EM Reveals Dynamics in the Murine Norovirus Capsid (2019) (2)
- Virus Assembly and Morphogenesis (1999) (2)
- The RNA pseudoknots in foot-and-mouth disease virus are dispensable for genome replication, but essential for the production of infectious virus (2020) (2)
- Thermal stabilization of enterovirus A 71 and production of antigenically stabilized empty capsids (2022) (2)
- Removing Unwanted Signals from HSQC Spectra (1996) (2)
- Structural and phenotypic analysis of Chikungunya Virus RNA structures during viral genome replication and translation (2019) (2)
- The Chikungunya virus nsP3 macro domain inhibits activation of the NF-κB pathway (2019) (2)
- Positive strand RNA viruses differ in the constraints they place on the folding of their negative strand (2022) (2)
- Higher-order structures of the foot-and-mouth disease virus RNA-dependent RNA polymerase required for dynamic inter-molecular interactions involved in viral genome replication (2020) (1)
- The broad-spectrum antiviral drug arbidol inhibits foot-and-mouth disease virus replication (2019) (1)
- A conserved glutathione binding site in poliovirus is a target for antivirals and vaccine stabilisation (2022) (1)
- Membrane Interactions and Uncoating of Aichi Virus, a Picornavirus That Lacks a VP4 (2022) (1)
- Structure-function analysis of the equine hepacivirus 5' untranslated region highlights the conservation of translational mechanisms across the hepaciviruses. (2019) (1)
- Production and Characterisation of Stabilised PV-3 Virus-like Particles Using Pichia pastoris (2022) (1)
- MS2-RNA hairpin (4one -5) complex (2000) (0)
- MS2-RNA HAIRPIN (2ONE -5) COMPLEX (2000) (0)
- Ms2-RNA Hairpin (C-10) Complex (2006) (0)
- Control Of Hepatitis E Virus Polyprotein Processing By Cellular Proteases (2022) (0)
- BACTERIOPHAGE MS2 CAPSID PROTEIN/RNA COMPLEX (1997) (0)
- STRUCTURE OF A PROTEIN CAPSID OF THE T45A MUTANT OF PHAGE MS2 (1997) (0)
- MS2-RNA HAIRPIN (5BRU -5) COMPLEX (2000) (0)
- Production of antigenically stable enterovirus A71 virus-like particles in Pichia pastoris as a vaccine candidate (2023) (0)
- stimulates RNA binding in an isomerase-dependent manner 2 (2011) (0)
- An upstream protein-coding region in enteroviruses modulates virus infection in gut epithelial cells (2018) (0)
- Targeting functional RNA structures in CHIKV and ZIKV (2019) (0)
- RNA-protein interactions in the ϕ29 molecular motor (2002) (0)
- Identification of putative packaging signals in the RNA of foot-and-mouth disease virus (FMDV) (2019) (0)
- Development of Enterovirus anti-viral agents that target the viral 2C protein (2022) (0)
- Polyprotein processing regulates FMDV replication (2023) (0)
- Crystal structure of a complex between WT bacteriophage MS2 coat protein and an F5 aptamer RNA stemloop with 2aminopurine substituted at the-10 position (2004) (0)
- Processing of the hepatitis E virus polyprotein can be mediated by a cellular protease (2022) (0)
- Functional RNA structures as targets in emerging arboviruses (2019) (0)
- Cryo-EM structure of ACP domain from Pichia pastoris fatty acid synthase (FAS) (2021) (0)
- Protease-Independent Production of Poliovirus Virus-like Particles in Pichia pastoris: Implications for Efficient Vaccine Development and Insights into Capsid Assembly (2022) (0)
- Crystal structure of human Enterovirus 71 in complex with the uncoating inhibitor GPP12 (2014) (0)
- Genetic evidence of a functional linkage between the RNA-dependent RNA polymerase and the highly structured S fragment located at the 5′ end of the genome of foot-and- mouth disease virus (2023) (0)
- MS2 (N87AE89K mutant) - RNA hairpin complex (2006) (0)
- F6 APTAMER MS2 COAT PROTEIN COMPLEX (1998) (0)
- Publisher Correction: A conserved glutathione binding site in poliovirus is a target for antivirals and vaccine stabilisation (2022) (0)
- RNA stemloop from bacteriophage Qbeta complexed with an N87S mutant MS2 Capsid (2006) (0)
- MS2-RNA HAIRPIN (2THIOURACIL-5) COMPLEX (2000) (0)
- STRUCTURE OF BACTERIOPHAGE COAT PROTEIN-LOOP RNA COMPLEX (1998) (0)
- MS2-RNA HAIRPIN (ADE-5) VIRUS COMPLEX (2000) (0)
- MS2 (N87AE89K mutant) - Qbeta RNA hairpin complex (2006) (0)
- VelcroVax: a ‘bolt-on’ vaccine platform technology improves antibody titres against a viral glycoprotein in mice (2022) (0)
- Inhibition of Chikungunya virus genome replication by targeting essential RNA structures within the virus genome. (2023) (0)
- Studies of RNA-Protein interactions and RNA structure utilising the bacteriophage MS2 capsid (2000) (0)
- MS2 PROTEIN CAPSID/RNA COMPLEX (1998) (0)
- RNA stemloop operator from bacteriophage QBETA complexed with an N87S,E89K mutant MS2 capsid (2006) (0)
- MS2 Wild-type RNA stemloop complexed with an N87S mutant MS2 capsid (2006) (0)
- STRUCTURE OF A MS2 COAT PROTEIN MUTANT IN COMPLEX WITH AN RNA OPERATOR (1997) (0)
- VelcroVax: a “Bolt-On” Vaccine Platform for Glycoprotein Display (2023) (0)
- Effect of proteins isolated from Brazilian snakes on enterovirus A71 replication cycle: An approach against hand, foot and mouth disease. (2023) (0)
- The RNA pseudoknots in foot-and-mouth disease virus are dispensable for genome replication, but essential for the production of infectious virus (2022) (0)
- MS2 (N87AE89K mutant) - Variant Qbeta RNA hairpin complex (2006) (0)
- Works for unaccompanied chorus (2002) (0)
- Evaluation of a range of mammalian and mosquito cell lines for use in Chikungunya virus research (2017) (0)
- MS2 (N87A mutant) - RNA hairpin complex (2006) (0)
- 43. Extracellular matrix processing and the control of enamel crystal growth (1991) (0)
- Amino acid substitutions in norovirus VP1 dictate cell tropism via an attachment process dependent on membrane mobility (2023) (0)
- Crystal structure of the nucleocapsid protein from Bunyamwera virus bound to RNA (2013) (0)
- Cryo-EM structure of murine norovirus (MNV-1) (2020) (0)
- Unravelling a co-nsP-iracy: the role of chikungunya virus non-structural protein 3 in replication and pathogenesis (2019) (0)
- Cryo-EM structure of fatty acid synthase (FAS) from Pichia pastoris (2021) (0)
- A highly discriminatory RNA strand-specific assay to facilitate analysis of the role of cis-acting elements in foot-and-mouth disease virus replication (2023) (0)
- Development of an ELISA to distinguish between foot-and-mouth disease virus infected and vaccinated animals utilising the viral non-structural protein 3ABC. (2022) (0)
- A novel enterovirus protein modulates infection in gut epithelial cells (2019) (0)
- Crystal structure of the nucleocapsid protein from Schmallenberg virus (2013) (0)
- High-risk human papillomavirus E 5 oncoprotein displays channel-7 forming activity sensitive to small molecule inhibitors (2012) (0)
- MS2-RNA HAIRPIN (2THIO-U -5-6) COMPLEX (2000) (0)
- RNA stemloop from bacteriophage MS2 complexed with an N87S,E89K mutant MS2 capsid (2006) (0)
- MS2-RNA HAIRPIN (2SU -5-6) COMPLEX (2006) (0)
- George Maciunas - Piano Piece #13 (Carpenter's Piece)(1962) (2006) (0)
- Stereoselectivity of Nitrone Addition to α‐ Diphenylphosphinoylalkenes. (1995) (0)
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